Ronald M. Lechan, M.D, Ph.D - Publications

Affiliations: 
1972 Brandeis University, Waltham, MA, United States 
 1976 University of Vermont College of Medicine, Burlington, VT, United States 
 1984 Department of Anatomy and Cellular Biology Tufts University Sackler School of Biomedical Research 
 1981- Division of Endocrinology Tufts Medical Center, Boston, MA, United States 
Area:
Hypothalamic disease, pituitary disease, disorders of the thyroid, adrenal disease, islet cell tumors
Website:
https://www.tuftsmedicalcenter.org/PhysicianDirectory/Ronald-Lechan.aspx?dpt=1c0141c2-4889-4ca1-85f2-95bd61056249

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mitra S, Basu S, Singh O, Lechan RM, Singru PS. Cocaine- and amphetamine-regulated transcript peptide- and dopamine-containing systems interact in the ventral tegmental area of the zebra finch, Taeniopygia guttata, during dynamic changes in energy status. Brain Structure & Function. PMID 34392422 DOI: 10.1007/s00429-021-02348-y  1
2021 Surbhi, Wittmann G, Low MJ, Lechan RM. Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency. Molecular Metabolism. 101312. PMID 34329773 DOI: 10.1016/j.molmet.2021.101312  1
2020 Grubbs EG, Lechan RM, Edeiken-Monroe B, Cote GJ, Trotter C, Tischler AS, Gagel RF. Early thyroidectomy in multiple endocrine neoplasia: a four decade experience. Endocrine-Related Cancer. PMID 32464600 DOI: 10.1530/Erc-20-0108  1
2020 Farkas E, Varga E, Kovács B, Szilvásy-Szabó A, Cote-Vélez A, Péterfi Z, Matziari M, Tóth M, Zelena D, Mezriczky Z, Kádár A, Kővári D, Watanabe M, Kano M, Mackie K, ... ... Lechan RM, et al. A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System. Iscience. 23: 100921. PMID 32143135 DOI: 10.1016/J.Isci.2020.100921  1
2019 Varga E, Farkas E, Zséli G, Kádár A, Venczel A, Kővári D, Németh D, Máté Z, Erdélyi F, Horváth A, Szenci O, Watanabe M, Lechan R, Gereben B, Fekete C. Thyrotropin-releasing-hormone-synthesizing neurons of the hypothalamic paraventricular nucleus are inhibited by glycinergic inputs. Thyroid : Official Journal of the American Thyroid Association. PMID 31659941 DOI: 10.1089/Thy.2019.0357  1
2019 Neumann HPH, Tsoy U, Bancos I, Amodru V, Walz MK, Tirosh A, Kaur RJ, McKenzie T, Qi X, Bandgar T, Petrov R, Yukina MY, Roslyakova A, van der Horst-Schrivers ANA, Berends AMA, ... ... Lechan RM, et al. Comparison of Pheochromocytoma-Specific Morbidity and Mortality Among Adults With Bilateral Pheochromocytomas Undergoing Total Adrenalectomy vs Cortical-Sparing Adrenalectomy. Jama Network Open. 2: e198898. PMID 31397861 DOI: 10.1001/jamanetworkopen.2019.8898  0.01
2019 Rosenblum JS, Maggio D, Pang Y, Nazari MA, Gonzales MK, Lechan RM, Smirniotopoulos JG, Zhuang Z, Pacak K, Heiss JD. Chiari Malformation Type 1 in -Associated Syndrome. International Journal of Molecular Sciences. 20. PMID 31185588 DOI: 10.3390/Ijms20112819  1
2019 Jones GL, Wittmann G, Yokosawa EB, Yu H, Mercer AJ, Lechan RM, Low MJ. Selective Restoration of Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network. Eneuro. 6. PMID 30957016 DOI: 10.1523/ENEURO.0400-18.2019  1
2019 Castillo MDD, Kung J, Lechan R. MON-329 Calcitonin-Secreting Neuroendocrine Tumor Raising Concern for Medullary Thyroid Carcinoma in a Patient with Thyroid Nodules Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-329  0.04
2018 Singh O, Pradhan DR, Nagalakashmi B, Kumar S, Mitra S, Sagarkar S, Sakharkar AJ, Lechan RM, Singru PS. Thyrotropin-releasing hormone (TRH) in the brain and pituitary of the teleost, Clarias batrachus and its role in regulation of hypophysiotropic dopamine neurons. The Journal of Comparative Neurology. PMID 30370602 DOI: 10.1002/Cne.24570  1
2018 Péterfi Z, Farkas I, Denis RGP, Farkas E, Uchigashima M, Füzesi T, Watanabe M, Lechan RM, Liposits Z, Luquet S, Fekete C. Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure. Molecular Metabolism. PMID 30274714 DOI: 10.1016/J.Molmet.2018.08.007  1
2018 Wittmann G, Lechan RM. Prss56 expression in the rodent hypothalamus: Inverse correlation with pro-opiomelanocortin suggests oscillatory gene expression in adult rat tanycytes. The Journal of Comparative Neurology. PMID 30242838 DOI: 10.1002/Cne.24504  1
2018 Anderson E, Heller RS, Lechan RM, Heilman CB. Regression of a nonfunctioning pituitary macroadenoma on the CDK4/6 inhibitor palbociclib: case report. Neurosurgical Focus. 44: E9. PMID 29852762 DOI: 10.3171/2018.2.Focus17660  0.01
2017 Mohácsik P, Erdélyi F, Baranyi M, Botz B, Szabó G, Tóth M, Haltrich I, Helyes Z, Sperlágh B, Tóth Z, Sinkó R, Lechan RM, Bianco AC, Fekete C, Gereben B. A transgenic mouse model for detection of tissue-specific thyroid hormone action. Endocrinology. PMID 29253128 DOI: 10.1210/En.2017-00582  1
2017 Péterfi Z, Farkas E, Nagyunyomi-Sényi K, Kádár A, Ottó S, Horváth A, Füzesi T, Lechan RM, Fekete C. Role of TRH/UCN3 neurons of the perifornical area/bed nucleus of stria terminalis region in the regulation of the anorexigenic POMC neurons of the arcuate nucleus in male mice and rats. Brain Structure & Function. PMID 29124350 DOI: 10.1007/S00429-017-1553-5  1
2017 Zséli G, Vida B, Szilvásy-Szabó A, Tóth M, Lechan RM, Fekete C. Neuronal connections of the central amygdalar nucleus with refeeding-activated brain areas in rats. Brain Structure & Function. PMID 28852859 DOI: 10.1007/S00429-017-1501-4  1
2017 Szilvásy-Szabó A, Varga E, Beliczai Z, Lechan RM, Fekete C. Localization of Connexin 43 Gap Junctions and Hemichannels in Tanycytes of Adult Mice. Brain Research. PMID 28803831 DOI: 10.1016/J.Brainres.2017.08.010  1
2016 Darr R, Nambuba J, Del Rivero J, Janssen I, Merino M, Todorovic M, Balint B, Jochmanova I, Prchal JT, Lechan R, Tischler AS, Popovic V, Miljic D, Adams KT, Prall FR, et al. Novel insights into the polycythemia-paraganglioma-somatostatinoma syndrome. Endocrine-Related Cancer. PMID 27679736 DOI: 10.1530/Erc-16-0231  1
2016 Liberatore A, Lechan RM. Bilateral Carotid-Cavernous Fistulas: An Uncommon Cause of Pituitary Enlargement and Hypopituitarism. Case Reports in Endocrinology. 2016: 6364203. PMID 27651959 DOI: 10.1155/2016/6364203  0.01
2016 Wittmann G, Farkas E, Szilvásy-Szabó A, Gereben B, Fekete C, Lechan RM. Variable proopiomelanocortin expression in tanycytes of the adult rat hypothalamus and pituitary stalk. The Journal of Comparative Neurology. PMID 27503597 DOI: 10.1002/Cne.24090  1
2016 Singh U, Kumar S, Shelkar GP, Yadhav M, Kokare DM, Goswami C, Lechan RM, Singru PS. Transient receptor potential vanilloid (TRPV3) in the ventral tegmental area of rat: Role in modulation of the mesolimbic-dopamine reward pathway. Neuropharmacology. PMID 27084697 DOI: 10.1016/J.Neuropharm.2016.04.012  1
2016 Singh O, Kumar S, Singh U, Kumar V, Lechan RM, Singru PS. Cocaine-and amphetamine regulated transcript peptide (CART) in the brain of zebra finch, Taeniopygia guttata: Organization, interaction with neuropeptide Y, and response to changes in energy status. The Journal of Comparative Neurology. PMID 27018984 DOI: 10.1002/Cne.24004  1
2016 Zséli G, Vida B, Martinez A, Lechan RM, Khan AM, Fekete C. Elucidation of the Anatomy of a Satiety Network: Focus on Connectivity of the Parabrachial Nucleus in the Adult Rat. The Journal of Comparative Neurology. PMID 26918800 DOI: 10.1002/Cne.23992  1
2015 Wittmann G, Mohácsik P, Balkhi MY, Gereben B, Lechan RM. Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice. Fluids and Barriers of the Cns. 12: 21. PMID 26337286 DOI: 10.1186/S12987-015-0016-8  1
2015 Martucci VL, Emaminia A, Del Rivero J, Lechan RM, Magoon BT, Galia A, Fojo T, Leung S, Lorusso R, Jimenez C, Shulkin BL, Audibert JL, Adams KT, Rosing DR, Vaidya A, et al. Succinate dehydrogenase gene mutations in cardiac paragangliomas. The American Journal of Cardiology. 115: 1753-9. PMID 25896150 DOI: 10.1016/J.Amjcard.2015.03.020  1
2015 Wittmann G, Szabon J, Mohácsik P, Nouriel SS, Gereben B, Fekete C, Lechan RM. Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents. Endocrinology. 156: 1552-64. PMID 25594699 DOI: 10.1210/En.2014-1830  1
2015 Werneck de Castro JP, Fonseca TL, Ueta CB, McAninch EA, Abdalla S, Wittmann G, Lechan RM, Gereben B, Bianco AC. Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine. The Journal of Clinical Investigation. 125: 769-81. PMID 25555216 DOI: 10.1172/Jci77588  1
2015 Turi GF, Wittmann G, Lechan RM, Losonczy A. Ambient GABA modulates septo-hippocampal inhibitory terminals via presynaptic GABAb receptors. Neuropharmacology. 88: 55-62. PMID 25446671 DOI: 10.1016/J.Neuropharm.2014.10.005  1
2014 Wittmann G, Harney JW, Singru PS, Nouriel SS, Reed Larsen P, Lechan RM. Inflammation-inducible type 2 deiodinase expression in the leptomeninges, choroid plexus, and at brain blood vessels in male rodents. Endocrinology. 155: 2009-19. PMID 24601886 DOI: 10.1210/En.2013-2154  1
2014 Fekete C, Lechan RM. Central regulation of hypothalamic-pituitary-thyroid axis under physiological and pathophysiological conditions. Endocrine Reviews. 35: 159-94. PMID 24423980 DOI: 10.1210/Er.2013-1087  1
2013 Patel FB, Khagi S, Daly KP, Lechan RM, Ummaritchot V, Saif MW. Pancreatic neuroendocrine tumor with ectopic adrenocorticotropin production: a case report and review of literature. Anticancer Research. 33: 4001-5. PMID 24023341  1
2013 Wittmann G, Hrabovszky E, Lechan RM. Distinct glutamatergic and GABAergic subsets of hypothalamic pro-opiomelanocortin neurons revealed by in situ hybridization in male rats and mice. The Journal of Comparative Neurology. 521: 3287-302. PMID 23640796 DOI: 10.1002/Cne.23350  1
2013 Fonseca TL, Correa-Medina M, Campos MP, Wittmann G, Werneck-de-Castro JP, Arrojo e Drigo R, Mora-Garzon M, Ueta CB, Caicedo A, Fekete C, Gereben B, Lechan RM, Bianco AC. Coordination of hypothalamic and pituitary T3 production regulates TSH expression. The Journal of Clinical Investigation. 123: 1492-500. PMID 23524969 DOI: 10.1172/Jci61231  1
2013 Pacak K, Jochmanova I, Prodanov T, Yang C, Merino MJ, Fojo T, Prchal JT, Tischler AS, Lechan RM, Zhuang Z. New syndrome of paraganglioma and somatostatinoma associated with polycythemia. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 1690-8. PMID 23509317 DOI: 10.1200/Jco.2012.47.1912  1
2013 Yang C, Sun MG, Matro J, Huynh TT, Rahimpour S, Prchal JT, Lechan R, Lonser R, Pacak K, Zhuang Z. Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas. Blood. 121: 2563-6. PMID 23361906 DOI: 10.1182/Blood-2012-10-460972  1
2012 Sárvári A, Farkas E, Kádár A, Zséli G, Füzesi T, Lechan RM, Fekete C. Thyrotropin-releasing hormone-containing axons innervate histaminergic neurons in the tuberomammillary nucleus. Brain Research. 1488: 72-80. PMID 23063458 DOI: 10.1016/J.Brainres.2012.10.010  1
2012 Fekete C, Zséli G, Singru PS, Kádár A, Wittmann G, Füzesi T, El-Bermani W, Lechan RM. Activation of anorexigenic pro-opiomelanocortin neurones during refeeding is independent of vagal and brainstem inputs. Journal of Neuroendocrinology. 24: 1423-31. PMID 22734660 DOI: 10.1111/J.1365-2826.2012.02354.X  1
2012 Kalló I, Mohácsik P, Vida B, Zeöld A, Bardóczi Z, Zavacki AM, Farkas E, Kádár A, Hrabovszky E, Arrojo E Drigo R, Dong L, Barna L, Palkovits M, Borsay BA, Herczeg L, ... Lechan RM, et al. A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons. Plos One. 7: e37860. PMID 22719854 DOI: 10.1371/Journal.Pone.0037860  1
2012 Singru PS, Wittmann G, Farkas E, Zséli G, Fekete C, Lechan RM. Refeeding-activated glutamatergic neurons in the hypothalamic paraventricular nucleus (PVN) mediate effects of melanocortin signaling in the nucleus tractus solitarius (NTS). Endocrinology. 153: 3804-14. PMID 22700769 DOI: 10.1210/En.2012-1235  1
2011 Marsili A, Sanchez E, Singru P, Harney JW, Zavacki AM, Lechan RM, Larsen PR. Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase. The Journal of Endocrinology. 211: 73-8. PMID 21788297 DOI: 10.1530/Joe-11-0248  1
2010 Rosene ML, Wittmann G, Arrojo e Drigo R, Singru PS, Lechan RM, Bianco AC. Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment. Endocrinology. 151: 5961-70. PMID 20926587 DOI: 10.1210/En.2010-0553  1
2010 Kádár A, Sánchez E, Wittmann G, Singru PS, Füzesi T, Marsili A, Larsen PR, Liposits Z, Lechan RM, Fekete C. Distribution of hypophysiotropic thyrotropin-releasing hormone (TRH)-synthesizing neurons in the hypothalamic paraventricular nucleus of the mouse. The Journal of Comparative Neurology. 518: 3948-61. PMID 20737594 DOI: 10.1002/Cne.22432  1
2010 Sánchez E, Singru PS, Wittmann G, Nouriel SS, Barrett P, Fekete C, Lechan RM. Contribution of TNF-alpha and nuclear factor-kappaB signaling to type 2 iodothyronine deiodinase activation in the mediobasal hypothalamus after lipopolysaccharide administration. Endocrinology. 151: 3827-35. PMID 20501675 DOI: 10.1210/En.2010-0279  1
2010 Freitas BC, Gereben B, Castillo M, Kalló I, Zeöld A, Egri P, Liposits Z, Zavacki AM, Maciel RM, Jo S, Singru P, Sanchez E, Lechan RM, Bianco AC. Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells. The Journal of Clinical Investigation. 120: 2206-17. PMID 20458138 DOI: 10.1172/Jci41977  1
2009 Wittmann G, Füzesi T, Liposits Z, Lechan RM, Fekete C. Distribution and axonal projections of neurons coexpressing thyrotropin-releasing hormone and urocortin 3 in the rat brain. The Journal of Comparative Neurology. 517: 825-40. PMID 19844978 DOI: 10.1002/Cne.22180  1
2009 Danilova OV, Tai AK, Mele DA, Beinborn M, Leiter AB, Greenberg AS, Perfield JW, Defuria J, Singru PS, Lechan RM, Huber BT. Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity. Endocrinology. 150: 5240-8. PMID 19819973 DOI: 10.1210/En.2009-0386  1
2009 Füzesi T, Wittmann G, Lechan RM, Liposits Z, Fekete C. Noradrenergic innervation of hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in rats. Brain Research. 1294: 38-44. PMID 19651110 DOI: 10.1016/J.Brainres.2009.07.094  1
2009 Wittmann G, Füzesi T, Singru PS, Liposits Z, Lechan RM, Fekete C. Efferent projections of thyrotropin-releasing hormone-synthesizing neurons residing in the anterior parvocellular subdivision of the hypothalamic paraventricular nucleus. The Journal of Comparative Neurology. 515: 313-30. PMID 19425088 DOI: 10.1002/Cne.22017  1
2009 Sánchez E, Vargas MA, Singru PS, Pascual I, Romero F, Fekete C, Charli JL, Lechan RM. Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-thyroid axis through glial-axonal associations in the median eminence. Endocrinology. 150: 2283-91. PMID 19179432 DOI: 10.1210/En.2008-1643  1
2009 Deli L, Wittmann G, Kalló I, Lechan RM, Watanabe M, Liposits Z, Fekete C. Type 1 cannabinoid receptor-containing axons innervate hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons. Endocrinology. 150: 98-103. PMID 18818298 DOI: 10.1210/En.2008-0330  1
2009 Lechan RM, Fekete C, Toni R. 39 – Thyroid Hormone in Neural Tissue Hormones, Brain and Behavior. 39: 1289-1330. DOI: 10.1016/B978-008088783-8.00039-5  1
2008 Lechan RM. The dilemma of the nonthyroidal illness syndrome. Acta Bio-Medica : Atenei Parmensis. 79: 165-71. PMID 19260375  0.01
2008 Singru PS, Mazumdar M, Barsagade V, Lechan RM, Thim L, Clausen JT, Subhedar N. Association of cocaine- and amphetamine-regulated transcript and neuropeptide Y in the forebrain and pituitary of the catfish, Clarias batrachus: a double immunofluorescent labeling study. Journal of Chemical Neuroanatomy. 36: 239-50. PMID 18675898 DOI: 10.1016/J.Jchemneu.2008.07.002  1
2008 Füzesi T, Sánchez E, Wittmann G, Singru PS, Fekete C, Lechan RM. Regulation of cocaine- and amphetamine-regulated transcript-synthesising neurons of the hypothalamic paraventricular nucleus by endotoxin; implications for lipopolysaccharide-induced regulation of energy homeostasis. Journal of Neuroendocrinology. 20: 1058-66. PMID 18624928 DOI: 10.1111/J.1365-2826.2008.01758.X  1
2008 Sánchez E, Singru PS, Acharya R, Bodria M, Fekete C, Zavacki AM, Bianco AC, Lechan RM. Differential effects of refeeding on melanocortin-responsive neurons in the hypothalamic paraventricular nucleus. Endocrinology. 149: 4329-35. PMID 18467436 DOI: 10.1210/En.2008-0411  1
2008 Sánchez E, Singru PS, Fekete C, Lechan RM. Induction of type 2 iodothyronine deiodinase in the mediobasal hypothalamus by bacterial lipopolysaccharide: role of corticosterone. Endocrinology. 149: 2484-93. PMID 18218695 DOI: 10.1210/En.2007-1697  1
2008 Singru PS, Sánchez E, Acharya R, Fekete C, Lechan RM. Mitogen-activated protein kinase contributes to lipopolysaccharide-induced activation of corticotropin-releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus. Endocrinology. 149: 2283-92. PMID 18187539 DOI: 10.1210/En.2007-1478  1
2008 Dandekar MP, Singru PS, Kokare DM, Lechan RM, Thim L, Clausen JT, Subhedar NK. Importance of cocaine- and amphetamine-regulated transcript peptide in the central nucleus of amygdala in anxiogenic responses induced by ethanol withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1127-36. PMID 17637604 DOI: 10.1038/Sj.Npp.1301516  1
2007 Füzesi T, Wittmann G, Liposits Z, Lechan RM, Fekete C. Contribution of noradrenergic and adrenergic cell groups of the brainstem and agouti-related protein-synthesizing neurons of the arcuate nucleus to neuropeptide-y innervation of corticotropin-releasing hormone neurons in hypothalamic paraventricular nucleus of the rat. Endocrinology. 148: 5442-50. PMID 17690163 DOI: 10.1210/En.2007-0732  1
2007 Fekete C, Freitas BC, Zeöld A, Wittmann G, Kádár A, Liposits Z, Christoffolete MA, Singru P, Lechan RM, Bianco AC, Gereben B. Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain. Endocrinology. 148: 4865-74. PMID 17628004 DOI: 10.1210/En.2007-0448  1
2007 Wajner SM, dos Santos Wagner M, Melo RC, Parreira GG, Chiarini-Garcia H, Bianco AC, Fekete C, Sanchez E, Lechan RM, Maia AL. Type 2 iodothyronine deiodinase is highly expressed in germ cells of adult rat testis. The Journal of Endocrinology. 194: 47-54. PMID 17592020 DOI: 10.1677/Joe-07-0106  1
2007 Fekete C, Lechan RM. Negative feedback regulation of hypophysiotropic thyrotropin-releasing hormone (TRH) synthesizing neurons: role of neuronal afferents and type 2 deiodinase. Frontiers in Neuroendocrinology. 28: 97-114. PMID 17588648 DOI: 10.1016/J.Yfrne.2007.04.002  1
2007 Menyhért J, Wittmann G, Lechan RM, Keller E, Liposits Z, Fekete C. Cocaine- and amphetamine-regulated transcript (CART) is colocalized with the orexigenic neuropeptide Y and agouti-related protein and absent from the anorexigenic alpha-melanocyte-stimulating hormone neurons in the infundibular nucleus of the human hypothalamus. Endocrinology. 148: 4276-81. PMID 17525122 DOI: 10.1210/En.2007-0390  1
2007 Lechan RM, Fekete C. Infundibular tanycytes as modulators of neuroendocrine function: hypothetical role in the regulation of the thyroid and gonadal axis. Acta Bio-Medica : Atenei Parmensis. 78: 84-98. PMID 17465327  1
2007 Toni R, Ghigo E, Roti E, Lechan RM. Endocrinology and art. Acromegaly and goiter in the Pre-Columbian, Mesoamerican population. Journal of Endocrinological Investigation. 30: 169-70. PMID 17392610 DOI: 10.1007/BF03347418  1
2007 Singru PS, Mazumdar M, Sakharkar AJ, Lechan RM, Thim L, Clausen JT, Subhedar NK. Immunohistochemical localization of cocaine- and amphetamine-regulated transcript peptide in the brain of the catfish, Clarias batrachus (Linn.). The Journal of Comparative Neurology. 502: 215-35. PMID 17348009 DOI: 10.1002/Cne.21295  1
2007 Neff LM, Weil M, Cole A, Hedges TR, Shucart W, Lawrence D, Zhu JJ, Tischler AS, Lechan RM. Temozolomide in the treatment of an invasive prolactinoma resistant to dopamine agonists. Pituitary. 10: 81-6. PMID 17285366 DOI: 10.1007/S11102-007-0014-1  1
2007 Sánchez E, Fekete C, Lechan RM, Joseph-Bravo P. Cocaine- and amphetamine-regulated transcript (CART) expression is differentially regulated in the hypothalamic paraventricular nucleus of lactating rats exposed to suckling or cold stimulation. Brain Research. 1132: 120-8. PMID 17174283 DOI: 10.1016/J.Brainres.2006.11.020  1
2007 Singru PS, Sánchez E, Fekete C, Lechan RM. Importance of melanocortin signaling in refeeding-induced neuronal activation and satiety. Endocrinology. 148: 638-46. PMID 17068131 DOI: 10.1210/En.2006-1233  1
2007 Fekete C, Lechan RM. Regulation of hypophysiotropic thyrotropin- and corticotrophin-releasing hormone neurons by feeding-related signals Collection of Czechoslovak Chemical Communications. 9: 43-48. DOI: 10.1135/Css200709043  1
2006 Lechan RM, Fekete C. Central mechanisms for thyroid hormone regulation. The American Journal of Psychiatry. 163: 1492. PMID 16946171 DOI: 10.1176/Ajp.2006.163.9.1492  1
2006 Lechan RM, Fekete C. The TRH neuron: a hypothalamic integrator of energy metabolism. Progress in Brain Research. 153: 209-35. PMID 16876577 DOI: 10.1016/S0079-6123(06)53012-2  1
2006 Fekete C, Lechan RM. Neuroendocrine implications for the association between cocaine- and amphetamine regulated transcript (CART) and hypophysiotropic thyrotropin-releasing hormone (TRH). Peptides. 27: 2012-8. PMID 16730860 DOI: 10.1016/J.Peptides.2005.11.029  1
2006 Christoffolete MA, Ribeiro R, Singru P, Fekete C, da Silva WS, Gordon DF, Huang SA, Crescenzi A, Harney JW, Ridgway EC, Larsen PR, Lechan RM, Bianco AC. Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism. Endocrinology. 147: 1735-43. PMID 16396983 DOI: 10.1210/En.2005-1300  1
2006 Lechan RM, Fekete C. Role of melanocortin signaling in the regulation of the hypothalamic-pituitary-thyroid (HPT) axis. Peptides. 27: 310-25. PMID 16310285 DOI: 10.1016/J.Peptides.2005.01.033  1
2006 Fekete C, Singru PS, Sanchez E, Sarkar S, Christoffolete MA, Riberio RS, Rand WM, Emerson CH, Bianco AC, Lechan RM. Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-thyroid axis and feeding-related neurons in the arcuate nucleus. Endocrinology. 147: 520-9. PMID 16210367 DOI: 10.1210/En.2005-0956  1
2005 Singru PS, Fekete C, Lechan RM. Neuroanatomical evidence for participation of the hypothalamic dorsomedial nucleus (DMN) in regulation of the hypothalamic paraventricular nucleus (PVN) by alpha-melanocyte stimulating hormone. Brain Research. 1064: 42-51. PMID 16336950 DOI: 10.1016/J.Brainres.2005.09.023  1
2005 Lechan RM, Fekete C. Role of thyroid hormone deiodination in the hypothalamus. Thyroid : Official Journal of the American Thyroid Association. 15: 883-97. PMID 16131331 DOI: 10.1089/Thy.2005.15.883  1
2005 Fekete C, Sarkar S, Christoffolete MA, Emerson CH, Bianco AC, Lechan RM. Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels. Brain Research. 1056: 97-9. PMID 16095572 DOI: 10.1016/J.Brainres.2005.07.021  1
2005 Toni R, Lechan RM, Mazzotti G. Goiter in the court of the Byzantine Empress, Theodora. Journal of Endocrinological Investigation. 28: 481. PMID 16075935 DOI: 10.1007/BF03347232  1
2005 Wittmann G, Liposits Z, Lechan RM, Fekete C. Origin of cocaine- and amphetamine-regulated transcript-containing axons innervating hypophysiotropic corticotropin-releasing hormone-synthesizing neurons in the rat. Endocrinology. 146: 2985-91. PMID 15831569 DOI: 10.1210/En.2005-0178  1
2005 Wittmann G, Lechan RM, Liposits Z, Fekete C. Glutamatergic innervation of corticotropin-releasing hormone- and thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. Brain Research. 1039: 53-62. PMID 15781046 DOI: 10.1016/J.Brainres.2005.01.090  1
2005 Fekete C, Sarkar S, Lechan RM. Relative contribution of brainstem afferents to the cocaine- and amphetamine-regulated transcript (CART) innervation of thyrotropin-releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus (PVN). Brain Research. 1032: 171-5. PMID 15680956 DOI: 10.1016/J.Brainres.2004.10.069  1
2005 Fekete C, Singru PS, Sarkar S, Rand WM, Lechan RM. Ascending brainstem pathways are not involved in lipopolysaccharide-induced suppression of thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus. Endocrinology. 146: 1357-63. PMID 15604205 DOI: 10.1210/En.2004-1429  1
2004 Lechan RM, Fekete C. Feedback regulation of thyrotropin-releasing hormone (TRH): mechanisms for the non-thyroidal illness syndrome. Journal of Endocrinological Investigation. 27: 105-19. PMID 15481810  1
2004 Fekete C, Marks DL, Sarkar S, Emerson CH, Rand WM, Cone RD, Lechan RM. Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse. Endocrinology. 145: 4816-21. PMID 15256492 DOI: 10.1210/En.2004-0476  1
2004 Toni R, Malaguti A, Castorina S, Roti E, Lechan RM. New paradigms in neuroendocrinology: relationships between obesity, systemic inflammation and the neuroendocrine system. Journal of Endocrinological Investigation. 27: 182-6. PMID 15129816 DOI: 10.1007/Bf03346266  1
2004 Wittmann G, Liposits Z, Lechan RM, Fekete C. Medullary adrenergic neurons contribute to the cocaine- and amphetamine-regulated transcript-immunoreactive innervation of thyrotropin-releasing hormone synthesizing neurons in the hypothalamic paraventricular nucleus. Brain Research. 1006: 1-7. PMID 15047018 DOI: 10.1016/J.Brainres.2003.12.049  1
2004 Wittmann G, Sarkar S, Hrabovszky E, Liposits Z, Lechan RM, Fekete C. Galanin- but not galanin-like peptide-containing axon terminals innervate hypophysiotropic TRH-synthesizing neurons in the hypothalamic paraventricular nucleus. Brain Research. 1002: 43-50. PMID 14988032 DOI: 10.1016/J.Brainres.2003.12.022  1
2004 Sarkar S, Wittmann G, Fekete C, Lechan RM. Central administration of cocaine- and amphetamine-regulated transcript increases phosphorylation of cAMP response element binding protein in corticotropin-releasing hormone-producing neurons but not in prothyrotropin-releasing hormone-producing neurons in the hypothalamic paraventricular nucleus. Brain Research. 999: 181-92. PMID 14759497 DOI: 10.1016/J.Brainres.2003.11.062  1
2004 Fekete C, Wittmann G, Liposits Z, Lechan RM. Origin of cocaine- and amphetamine-regulated transcript (CART)-immunoreactive innervation of the hypothalamic paraventricular nucleus. The Journal of Comparative Neurology. 469: 340-50. PMID 14730586 DOI: 10.1002/Cne.10999  1
2004 Raptis S, Fekete C, Sarkar S, Rand WM, Emerson CH, Nagy GM, Lechan RM. Cocaine- and amphetamine-regulated transcript co-contained in thyrotropin-releasing hormone (TRH) neurons of the hypothalamic paraventricular nucleus modulates TRH-induced prolactin secretion. Endocrinology. 145: 1695-9. PMID 14691017 DOI: 10.1210/En.2003-1576  1
2004 Fekete C, Gereben B, Doleschall M, Harney JW, Dora JM, Bianco AC, Sarkar S, Liposits Z, Rand W, Emerson C, Kacskovics I, Larsen PR, Lechan RM. Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonthyroidal illness syndrome. Endocrinology. 145: 1649-55. PMID 14684601 DOI: 10.1210/En.2003-1439  1
2003 Schumann R, Joseph N, Zabala L, Schwaitzberg SD, Lechan RM. Hypertensive crisis inducing rhabdomyolysis during laparoscopic resection of a large pheochromocytoma: a case report. Journal of Clinical Anesthesia. 15: 540-4. PMID 14698369 DOI: 10.1016/J.Jclinane.2003.02.006  1
2003 Sarkar S, Fekete C, Légrádi G, Lechan RM. Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Brain Research. 985: 163-8. PMID 12967720 DOI: 10.1016/S0006-8993(03)03117-2  1
2003 Sarkar S, Lechan RM. Central administration of neuropeptide Y reduces alpha-melanocyte-stimulating hormone-induced cyclic adenosine 5'-monophosphate response element binding protein (CREB) phosphorylation in pro-thyrotropin-releasing hormone neurons and increases CREB phosphorylation in corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology. 144: 281-91. PMID 12488356 DOI: 10.1210/En.2002-220675  1
2002 Fekete C, Sarkar S, Rand WM, Harney JW, Emerson CH, Bianco AC, Beck-Sickinger A, Lechan RM. Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis. Endocrinology. 143: 4513-9. PMID 12446577 DOI: 10.1210/En.2002-220574  1
2002 Fekete C, Wittmann G, Liposits Z, Lechan RM. GABA-ergic innervation of thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. Brain Research. 957: 251-8. PMID 12445967 DOI: 10.1016/S0006-8993(02)03576-X  1
2002 Fekete C, Sarkar S, Rand WM, Harney JW, Emerson CH, Bianco AC, Lechan RM. Agouti-related protein (AGRP) has a central inhibitory action on the hypothalamic-pituitary-thyroid (HPT) axis; comparisons between the effect of AGRP and neuropeptide Y on energy homeostasis and the HPT axis. Endocrinology. 143: 3846-53. PMID 12239096 DOI: 10.1210/En.2002-220338  1
2002 Hahm S, Fekete C, Mizuno TM, Windsor J, Yan H, Boozer CN, Lee C, Elmquist JK, Lechan RM, Mobbs CV, Salton SR. VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6929-38. PMID 12177191 DOI: 10.1523/Jneurosci.22-16-06929.2002  1
2002 Sarkar S, Légrádi G, Lechan RM. Intracerebroventricular administration of alpha-melanocyte stimulating hormone increases phosphorylation of CREB in TRH- and CRH-producing neurons of the hypothalamic paraventricular nucleus. Brain Research. 945: 50-9. PMID 12113951 DOI: 10.1016/S0006-8993(02)02619-7  1
2002 Wittmann G, Liposits Z, Lechan RM, Fekete C. Medullary adrenergic neurons contribute to the neuropeptide Y-ergic innervation of hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in the rat. Neuroscience Letters. 324: 69-73. PMID 11983297 DOI: 10.1016/S0304-3940(02)00165-9  1
2002 Nillni EA, Lee A, Legradi G, Lechan RM. Effect of precipitated morphine withdrawal on post-translational processing of prothyrotropin releasing hormone (proTRH) in the ventrolateral column of the midbrain periaqueductal gray. Journal of Neurochemistry. 80: 874-84. PMID 11948251 DOI: 10.1046/J.0022-3042.2002.00763.X  1
2002 Mihály E, Fekete C, Lechan RM, Liposits Z. Corticotropin-releasing hormone-synthesizing neurons of the human hypothalamus receive neuropeptide Y-immunoreactive innervation from neurons residing primarily outside the infundibular nucleus. The Journal of Comparative Neurology. 446: 235-43. PMID 11932939 DOI: 10.1002/Cne.10193  1
2002 Lechan RM, Toni R. Thyroid Hormones in Neural Tissue Hormones, Brain and Behavior. 157-238. DOI: 10.1016/B978-012532104-4/50022-6  1
2001 Margiloff L, Harris SS, Lee S, Lechan R, Dawson-Hughes B. Vitamin D status of an outpatient clinic population. Calcified Tissue International. 69: 263-267. PMID 11768195 DOI: 10.1007/S002230010054  0.08
2001 Mihaly E, Legradi G, Fekete C, Lechan RM. Efferent projections of ProTRH neurons in the ventrolateral periaqueductal gray. Brain Research. 919: 185-97. PMID 11701131 DOI: 10.1016/S0006-8993(01)02962-6  1
2001 Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Molecular Endocrinology (Baltimore, Md.). 15: 1748-57. PMID 11579207 DOI: 10.1210/Mend.15.10.0706  1
2001 Luo LG, Lee SL, Lechan RM, Jackson IM. Effect of preproTRH antisense on thyrotropin-releasing hormone synthesis and viability of cultured rat diencephalic neurons. Endocrine. 15: 79-85. PMID 11577700 DOI: 10.1385/Endo:15:1:079  1
2001 Lechan RM, Tatro JB. Hypothalamic melanocortin signaling in cachexia. Endocrinology. 142: 3288-91. PMID 11459769 DOI: 10.1210/Endo.142.8.8408  1
2001 Peeters R, Fekete C, Goncalves C, Legradi G, Tu HM, Harney JW, Bianco AC, Lechan RM, Larsen PR. Regional physiological adaptation of the central nervous system deiodinases to iodine deficiency. American Journal of Physiology. Endocrinology and Metabolism. 281: E54-61. PMID 11404222 DOI: 10.1152/Ajpendo.2001.281.1.E54  1
2001 Fekete C, Kelly J, Mihály E, Sarkar S, Rand WM, Légrádi G, Emerson CH, Lechan RM. Neuropeptide Y has a central inhibitory action on the hypothalamic-pituitary-thyroid axis. Endocrinology. 142: 2606-13. PMID 11356711 DOI: 10.1210/Endo.142.6.8207  1
2001 Mihály E, Fekete C, Légrádi G, Lechan RM. Hypothalamic dorsomedial nucleus neurons innervate thyrotropin-releasing hormone-synthesizing neurons in the paraventricular nucleus. Brain Research. 891: 20-31. PMID 11164806 DOI: 10.1016/S0006-8993(00)03094-8  1
2000 Fekete C, Mihály E, Luo LG, Kelly J, Clausen JT, Mao Q, Rand WM, Moss LG, Kuhar M, Emerson CH, Jackson IM, Lechan RM. Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9224-34. PMID 11125000  1
2000 Fekete C, Légrádi G, Mihály E, Tatro JB, Rand WM, Lechan RM. alpha-Melanocyte stimulating hormone prevents fasting-induced suppression of corticotropin-releasing hormone gene expression in the rat hypothalamic paraventricular nucleus. Neuroscience Letters. 289: 152-6. PMID 10904142 DOI: 10.1016/S0304-3940(00)01256-8  1
2000 Mihály E, Fekete C, Tatro JB, Liposits Z, Stopa EG, Lechan RM. Hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in the human hypothalamus are innervated by neuropeptide Y, agouti-related protein, and alpha-melanocyte-stimulating hormone. The Journal of Clinical Endocrinology and Metabolism. 85: 2596-603. PMID 10902813 DOI: 10.1210/Jcem.85.7.6662  1
2000 Fekete C, Mihály E, Herscovici S, Salas J, Tu H, Larsen PR, Lechan RM. DARPP-32 and CREB are present in type 2 iodothyronine deiodinase-producing tanycytes: implications for the regulation of type 2 deiodinase activity. Brain Research. 862: 154-61. PMID 10799680 DOI: 10.1016/S0006-8993(00)02105-3  1
2000 Fekete C, Légrádi G, Mihály E, Huang QH, Tatro JB, Rand WM, Emerson CH, Lechan RM. alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 1550-8. PMID 10662844 DOI: 10.1523/Jneurosci.20-04-01550.2000  1
2000 Fekete C, Mihály E, Luo LG, Kelly J, Clausen JT, Mao QF, Rand WM, Moss LG, Kuhar M, Emerson CH, Jackson IMD, Lechan RM. Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. The Journal of Neuroscience. 20: 9224-9234. DOI: 10.1523/Jneurosci.20-24-09224.2000  1
1999 Légrádi G, Lechan RM. Agouti-related protein containing nerve terminals innervate thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology. 140: 3643-52. PMID 10433222 DOI: 10.1210/Endo.140.8.6935  1
1999 Tu HM, Legradi G, Bartha T, Salvatore D, Lechan RM, Larsen PR. Regional expression of the type 3 iodothyronine deiodinase messenger ribonucleic acid in the rat central nervous system and its regulation by thyroid hormone. Endocrinology. 140: 784-90. PMID 9927306 DOI: 10.1210/Endo.140.2.6486  1
1998 Légrádi G, Hannibal J, Lechan RM. Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat. Neuroscience Letters. 246: 145-8. PMID 9792613 DOI: 10.1016/S0304-3940(98)00255-9  1
1998 Legradi G, Emerson CH, Ahima RS, Rand WM, Flier JS, Lechan RM. Arcuate nucleus ablation prevents fasting-induced suppression of ProTRH mRNA in the hypothalamic paraventricular nucleus. Neuroendocrinology. 68: 89-97. PMID 9705575 DOI: 10.1159/000054354  1
1998 Légrádi G, Lechan RM. The arcuate nucleus is the major source for neuropeptide Y-innervation of thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology. 139: 3262-70. PMID 9645702 DOI: 10.1210/Endo.139.7.6113  1
1997 Légrádi G, Hannibal J, Lechan RM. Association between pituitary adenylate cyclase-activating polypeptide and thyrotropin-releasing hormone in the rat hypothalamus. Journal of Chemical Neuroanatomy. 13: 265-79. PMID 9412908 DOI: 10.1016/S0891-0618(97)10002-3  1
1997 Légrádi G, Holzer D, Kapcala LP, Lechan RM. Glucocorticoids inhibit stress-induced phosphorylation of CREB in corticotropin-releasing hormone neurons of the hypothalamic paraventricular nucleus. Neuroendocrinology. 66: 86-97. PMID 9263205 DOI: 10.1159/000127224  1
1997 Tu HM, Kim SW, Salvatore D, Bartha T, Legradi G, Larsen PR, Lechan RM. Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone. Endocrinology. 138: 3359-68. PMID 9231788 DOI: 10.1210/Endo.138.8.5318  1
1997 Chattopadhyay N, Legradi G, Bai M, Kifor O, Ye C, Vassilev PM, Brown EM, Lechan RM. Calcium-sensing receptor in the rat hippocampus: a developmental study. Brain Research. Developmental Brain Research. 100: 13-21. PMID 9174241 DOI: 10.1016/S0165-3806(97)00009-6  1
1997 Légrádi G, Emerson CH, Ahima RS, Flier JS, Lechan RM. Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology. 138: 2569-76. PMID 9165050 DOI: 10.1210/Endo.138.6.5209  1
1997 Brady S, Lechan RM, Schwaitzberg SD, Dayal Y, Ziar J, Tischler AS. Composite pheochromocytoma/ganglioneuroma of the adrenal gland associated with multiple endocrine neoplasia 2A: case report with immunohistochemical analysis. The American Journal of Surgical Pathology. 21: 102-8. PMID 8990146 DOI: 10.1097/00000478-199701000-00011  1
1996 Légrádi G, Rand WM, Hitz S, Nillni EA, Jackson IM, Lechan RM. Opiate withdrawal increases ProTRH gene expression in the ventrolateral column of the midbrain periaqueductal gray. Brain Research. 729: 10-19. PMID 8874872 DOI: 10.1016/S0006-8993(96)00210-7  1
1996 Romero LI, Kakucska I, Lechan RM, Reichlin S. Interleukin-6 (IL-6) is secreted from the brain after intracerebroventricular injection of IL-1 beta in rats. The American Journal of Physiology. 270: R518-24. PMID 8780215 DOI: 10.1152/Ajpregu.1996.270.3.R518  1
1995 Sugawara A, Yen PM, Qi Y, Lechan RM, Chin WW. Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland. Endocrinology. 136: 1766-74. PMID 7895689 DOI: 10.1210/Endo.136.4.7895689  1
1995 Kakucska I, Qi Y, Lechan RM. Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone. Endocrinology. 136: 2795-802. PMID 7789304 DOI: 10.1210/Endo.136.7.7789304  1
1995 Pauker SG, Kopelman RI, Lechan RM. Clinical problem-solving. Diverted by the chief complaint. The New England Journal of Medicine. 333: 45-8. PMID 7776994 DOI: 10.1056/Nejm199507063330109  0.01
1995 Toni R, Mosca S, Ruggeri F, Valmori A, Orlandi G, Toni G, Lechan RM, Vezzadini P. Effect of hypothyroidism on vasoactive intestinal polypeptide-immunoreactive neurons in forebrain-neurohypophysial nuclei of the rat brain. Brain Research. 682: 101-15. PMID 7552300 DOI: 10.1016/0006-8993(95)00340-V  1
1994 Kakucska I, Romero LI, Clark BD, Rondeel JM, Qi Y, Alex S, Emerson CH, Lechan RM. Suppression of thyrotropin-releasing hormone gene expression by interleukin-1-beta in the rat: implications for nonthyroidal illness. Neuroendocrinology. 59: 129-37. PMID 8127401 DOI: 10.1159/000126649  1
1994 Lechan RM, Qi Y, Jackson IM, Mahdavi V. Identification of thyroid hormone receptor isoforms in thyrotropin-releasing hormone neurons of the hypothalamic paraventricular nucleus. Endocrinology. 135: 92-100. PMID 7516871 DOI: 10.1210/Endo.135.1.7516871  1
1993 Romero LI, Schettini G, Lechan RM, Dinarello CA, Reichlin S. Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1. Neuroendocrinology. 57: 892-7. PMID 8413826 DOI: 10.1159/000126450  1
1993 Kakucska I, Qi Y, Clark BD, Lechan RM. Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1. Endocrinology. 133: 815-21. PMID 8344218 DOI: 10.1210/Endo.133.2.8344218  1
1993 Toni R, Lechan RM. Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system. Journal of Endocrinological Investigation. 16: 715-53. PMID 8282969 DOI: 10.1007/Bf03348918  1
1993 Lechan RM, Qi Y, Berrodin TJ, Davis KD, Schwartz HL, Strait KA, Oppenheimer JH, Lazar MA. Immunocytochemical delineation of thyroid hormone receptor beta 2-like immunoreactivity in the rat central nervous system. Endocrinology. 132: 2461-9. PMID 7684976 DOI: 10.1210/Endo.132.6.7684976  1
1992 Cook CB, Kakucska I, Lechan RM, Koenig RJ. Expression of thyroid hormone receptor β2 in rat hypothalamus Endocrinology. 130: 1077-1079. PMID 1733708 DOI: 10.1210/Endo.130.2.1733708  1
1992 Toni R, Kakucska I, Mosca S, Marrama P, Lechan RM. Hypothyroidism increases vasoactive intestinal polypeptide (VIP) immunoreactivity and gene expression in the rat hypothalamic paraventricular nucleus. Endocrinology. 131: 976-8. PMID 1639036 DOI: 10.1210/Endo.131.2.1639036  1
1992 Kakucska I, Rand W, Lechan RM. Thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is dependent upon feedback regulation by both triiodothyronine and thyroxine. Endocrinology. 130: 2845-50. PMID 1572297 DOI: 10.1210/Endo.130.5.1572297  1
1992 Sauter NP, Atkins MB, Mier JW, Lechan RM. Transient thyrotoxicosis and persistent hypothyroidism due to acute autoimmune thyroiditis after interleukin-2 and interferon-alpha therapy for metastatic carcinoma: a case report. The American Journal of Medicine. 92: 441-4. PMID 1558092 DOI: 10.1016/0002-9343(92)90278-J  1
1992 Lechan RM, Kakucska I. Feedback regulation of thyrotropin-releasing hormone gene expression by thyroid hormone in the hypothalamic paraventricular nucleus. Ciba Foundation Symposium. 168: 144-58; discussion 1. PMID 1425022  1
1992 Lechan R. Book Review Brain Endocrinology (Comprehensive Endocrinology: Revised series.) Second edition. Edited by Marcella Motta. 482 pp., illustrated. New York, Raven Press, 1991. $145. The New England Journal of Medicine. 326: 1168-1168. DOI: 10.1056/Nejm199204233261724  0.04
1991 Van den Bergh P, Octave JN, Lechan RM. Muscle denervation increases thyrotropin-releasing hormone (TRH) biosynthesis in the rat medullary raphe. Brain Research. 566: 219-24. PMID 1814539 DOI: 10.1016/0006-8993(91)91702-3  1
1990 Lechan RM, Toni R, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Reichlin S. Immunoreactive interleukin-1β localization in the rat forebrain Brain Research. 514: 135-140. PMID 2357520 DOI: 10.1016/0006-8993(90)90445-H  1
1990 Schipper HM, Lechan RM, Reichlin S. Glial peroxidase activity in the hypothalamic arcuate nucleus: effects of estradiol valerate-induced persistent estrus. Brain Research. 507: 200-7. PMID 2337760 DOI: 10.1016/0006-8993(90)90273-E  1
1990 Koenig JI, Snow K, Clark BD, Toni R, Cannon JG, Shaw AR, Dinarello CA, Reichlin S, Lee SL, Lechan RM. Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide. Endocrinology. 126: 3053-8. PMID 2190803 DOI: 10.1210/Endo-126-6-3053  1
1990 Sauter NP, Toni R, McLaughlin CD, Dyess EM, Kritzman J, Lechan RM. Isolated adrenocorticotropin deficiency associated with an autoantibody to a corticotroph antigen that is not adrenocorticotropin or other proopiomelanocortin-derived peptides. The Journal of Clinical Endocrinology and Metabolism. 70: 1391-7. PMID 2159484 DOI: 10.1210/jcem-70-5-1391  1
1990 Lam KS, Srivastava G, Lechan RM, Lee T, Reichlin S. Estrogen regulates the gene expression of vasoactive intestinal peptide in the anterior pituitary. Neuroendocrinology. 52: 417-21. PMID 2126350 DOI: 10.1159/000125622  1
1990 Aratan-Spire S, Scharfmann R, Lechan RM, Tashjian AH. proTRH gene expression by fetal pancreatic islets in culture. Biochemical and Biophysical Research Communications. 168: 952-8. PMID 2111993 DOI: 10.1016/0006-291X(90)91121-8  0.01
1990 Toni R, Jackson IM, Lechan RM. Neuropeptide-Y-immunoreactive innervation of thyrotropin-releasing hormone-synthesizing neurons in the rat hypothalamic paraventricular nucleus. Endocrinology. 126: 2444-53. PMID 2109687 DOI: 10.1210/Endo-126-5-2444  1
1990 Toni R, Lechan RM. 1-naphthol-pyronin B as a novel substrate for silver intensification: application to light and electron microscopic immunocytochemistry of neuroendocrine systems. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 38: 1209-14. PMID 1973180 DOI: 10.1177/38.8.1973180  1
1990 Toni R, Jackson IM, Lechan RM. Thyrotropin-releasing-hormone-immunoreactive innervation of thyrotropin-releasing-hormone-tuberoinfundibular neurons in rat hypothalamus: anatomical basis to suggest ultrashort feedback regulation. Neuroendocrinology. 52: 422-8. PMID 1704108 DOI: 10.1159/000125623  1
1990 Schipper HM, Scarborough DE, Lechan RM, Reichlin S. Gomori-positive astrocytes in primary culture: effects of in vitro age and cysteamine exposure. Brain Research. Developmental Brain Research. 54: 71-9. PMID 1694746 DOI: 10.1016/0165-3806(90)90066-8  1
1989 Lam KS, Lechan RM, Minamitani N, Segerson TP, Reichlin S. Vasoactive intestinal peptide in the anterior pituitary is increased in hypothyroidism. Endocrinology. 124: 1077-84. PMID 2912685 DOI: 10.1210/Endo-124-2-1077  1
1989 Segerson TP, Lam KS, Cacicedo L, Minamitani N, Fink JS, Lechan RM, Reichlin S. Thyroid hormone regulates vasoactive intestinal peptide (VIP) mRNA levels in the rat anterior pituitary gland. Endocrinology. 125: 2221-3. PMID 2791988 DOI: 10.1210/Endo-125-4-2221  1
1989 Munsat TL, Lechan R, Taft JM, Jackson IMD, Reichlin S. TRH and diseases of the motor system. Annals of the New York Academy of Sciences. 553: 388-398. DOI: 10.1111/J.1749-6632.1989.Tb54507.X  1
1989 Lechan RM, Segerson TP. Pro‐TRH Gene Expression and Precursor Peptides in Rat Brain: Annals of the New York Academy of Sciences. 553: 29-59. DOI: 10.1111/J.1749-6632.1989.Tb54476.X  1
1988 Van Den Bergh P, Kelly JJ, Soule N, Munsat TL, Jackson I, Lechan RM. Spinal cord TRH deficiency is associated with incomplete recovery of denervatedmuscle in the rat Neurology. 38: 452-458. PMID 3126409 DOI: 10.1212/Wnl.38.3.452  1
1987 Segerson TP, Kauer J, Wolfe HC, Mobtaker H, Wu P, Jackson IMD, Lechan RM. Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus Science. 238: 78-80. PMID 3116669 DOI: 10.1126/Science.3116669  1
1987 van Den Bergh P, Kelly JJ, Adelman L, Munsat TL, Jackson IM, Lechan RM. Effect of spinal cord TRH deficiency on lower motorneuron function in the rat Muscle and Nerve. 10: 397-405. PMID 3112570 DOI: 10.1002/Mus.880100504  1
1986 Hayes DF, Lechan RM, Posner MR, Weichselbaum RR, Miller D, Ervin TJ. The syndrome of inappropriate antidiuretic hormone secretion associated with induction chemotherapy for squamous cell carcinoma of the head and neck. Journal of Surgical Oncology. 32: 150-2. PMID 3525992 DOI: 10.1016/S0022-5347(17)44372-2  1
1986 Jackson IM, Adelman LS, Munsat TL, Forte S, Lechan RM. Amyotrophic lateral sclerosis: thyrotropin-releasing hormone and histidyl proline diketopiperazine in the spinal cord and cerebrospinal fluid. Neurology. 36: 1218-23. PMID 3092130 DOI: 10.1212/Wnl.36.9.1218  1
1986 Lechan RM, Wu P, Jackson IM, Wolf H, Cooperman S, Mandel G, Goodman RH. Thyrotropin-releasing hormone precursor: characterization in rat brain. Science (New York, N.Y.). 231: 159-61. PMID 3079917 DOI: 10.1126/Science.3079917  1
1986 Low MJ, Lechan RM, Hammer RE, Brinster RL, Habener JF, Mandel G, Goodman RH. Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. Science (New York, N.Y.). 231: 1002-4. PMID 2868526 DOI: 10.1126/Science.2868526  1
1986 Hoefler H, Childers H, Montminy MR, Lechan RM, Goodman RH, Wolfe HJ. In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes. The Histochemical Journal. 18: 597-604. PMID 2435682 DOI: 10.1007/Bf01675295  1
1983 Lechan RM, Goodman RH, Rosenblatt M, Reichlin S, Habener JF. Prosomatostatin-specific antigen in rat brain: localization by immunocytochemical staining with an antiserum to a synthetic sequence of preprosomatostatin. Proceedings of the National Academy of Sciences of the United States of America. 80: 2780-4. PMID 6133283 DOI: 10.1073/Pnas.80.9.2780  1
1983 Leccese AP, Wehrenberg WB, Ling N, Tramu G, Croix C, Pillez A, Gold MA, Heydorn WE, Creed J, Jacobowitz DM, Perkins SN, Evans WS, Thorner MO, Cronin MJ, Werner S, ... ... Lechan R, et al. Subject Index Vol. 37, 1983 Neuroendocrinology. 37: 481-482. DOI: 10.1159/000123600  1
1983 Leccese AP, Wehrenberg WB, Ling N, Tramu G, Croix C, Pillez A, Gold MA, Heydorn WE, Creed J, Jacobowitz DM, Perkins SN, Evans WS, Thorner MO, Cronin MJ, Werner S, ... ... Lechan R, et al. Contents, Vol. 37, 1983 Neuroendocrinology. 37. DOI: 10.1159/000123582  1
1983 Lechan RM. The role of peptides and amino acids as neurotransmitters. Edited by J. Barry Lombardini, Alexander D. Kenny, 232 pp, Alan R. Liss, Inc., New York, NY, 1981. $36.00 Muscle & Nerve. 6: 78-78. DOI: 10.1002/Mus.880060115  0.01
1976 Lechan RM, Alpert LC, Jackson IMD. Synthesis of luteinising hormone releasing factor and thyrotropin-releasing factor in glutamate-lesioned mice Nature. 264: 463-465. PMID 826829 DOI: 10.1038/264463A0  1
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