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Christian Dibble, PHD - Publications

Affiliations: 
Genetics and Complex Diseases Harvard School of Public Health, Boston, MA, United States 
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Manning BD, Dibble CC. Growth Signaling Networks Orchestrate Cancer Metabolic Networks. Cold Spring Harbor Perspectives in Medicine. PMID 38438221 DOI: 10.1101/cshperspect.a041543  0.621
2023 Zhang HH, Lipovsky AI, Dibble CC, Sahin M, Manning BD. S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt. Molecular Cell. 83: 3217. PMID 37683612 DOI: 10.1016/j.molcel.2023.08.003  0.394
2023 Zhang T, Xu D, Trefts E, Lv M, Inuzuka H, Song G, Liu M, Lu J, Liu J, Chu C, Wang M, Wang H, Meng H, Liu H, Zhuang Y, ... ... Dibble CC, et al. Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.). 380: 1372-1380. PMID 37384704 DOI: 10.1126/science.abn1725  0.39
2022 Dibble CC, Barritt SA, Perry GE, Lien EC, Geck RC, DuBois-Coyne SE, Bartee D, Zengeya TT, Cohen EB, Yuan M, Hopkins BD, Meier JL, Clohessy JG, Asara JM, Cantley LC, et al. PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Nature. PMID 35896750 DOI: 10.1038/s41586-022-04984-8  0.548
2022 Jouandin P, Marelja Z, Shih YH, Parkhitko AA, Dambowsky M, Asara JM, Nemazanyy I, Dibble CC, Simons M, Perrimon N. Lysosomal cystine mobilization shapes the response of TORC1 and tissue growth to fasting. Science (New York, N.Y.). 375: eabc4203. PMID 35175796 DOI: 10.1126/science.abc4203  0.369
2019 Kang YP, Torrente L, Falzone A, Elkins CM, Liu M, Asara JM, Dibble CC, DeNicola G. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. Elife. 8. PMID 31107239 DOI: 10.7554/Elife.45572  0.332
2018 Toker A, Dibble CC. PI 3-Kinase Signaling: AKTing up inside the Cell. Molecular Cell. 71: 875-876. PMID 30241602 DOI: 10.1016/J.Molcel.2018.09.006  0.636
2017 Lien EC, Dibble CC, Toker A. PI3K signaling in cancer: beyond AKT. Current Opinion in Cell Biology. 45: 62-71. PMID 28343126 DOI: 10.1016/J.Ceb.2017.02.007  0.587
2016 Ricoult SJ, Dibble CC, Asara JM, Manning BD. SREBP regulates the expression and metabolic functions of wild-type and oncogenic IDH1. Molecular and Cellular Biology. PMID 27354064 DOI: 10.1128/Mcb.00163-16  0.335
2015 Dibble CC, Cantley LC. Regulation of mTORC1 by PI3K signaling. Trends in Cell Biology. 25: 545-55. PMID 26159692 DOI: 10.1016/J.Tcb.2015.06.002  0.66
2015 Dibble CC, Cantley LC. Regulation of mTORC1 by PI3K signaling Trends in Cell Biology. DOI: 10.1016/j.tcb.2015.06.002  0.614
2014 Menon S, Dibble CC, Talbott G, Hoxhaj G, Valvezan AJ, Takahashi H, Cantley LC, Manning BD. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome. Cell. 156: 771-85. PMID 24529379 DOI: 10.1016/J.Cell.2013.11.049  0.535
2013 Dibble CC, Manning BD. Signal integration by mTORC1 coordinates nutrient input with biosynthetic output. Nature Cell Biology. 15: 555-64. PMID 23728461 DOI: 10.1038/Ncb2763  0.551
2012 Dibble CC, Elis W, Menon S, Qin W, Klekota J, Asara JM, Finan PM, Kwiatkowski DJ, Murphy LO, Manning BD. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1. Molecular Cell. 47: 535-46. PMID 22795129 DOI: 10.1016/J.Molcel.2012.06.009  0.31
2011 Tanaka K, Babic I, Nathanson D, Akhavan D, Guo D, Gini B, Dang J, Zhu S, Yang H, De Jesus J, Amzajerdi AN, Zhang Y, Dibble CC, Dan H, Rinkenbaugh A, et al. Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance. Cancer Discovery. 1: 524-38. PMID 22145100 DOI: 10.1158/2159-8290.Cd-11-0124  0.519
2010 Dibble CC, Manning BD. The TSC1-TSC2 complex. A key signal-integrating node upstream of TOR Enzymes. 28: 21-48. DOI: 10.1016/S1874-6047(10)28002-2  0.482
2009 Dibble CC, Manning BD. A molecular link between AKT regulation and chemotherapeutic response. Cancer Cell. 16: 178-80. PMID 19732717 DOI: 10.1016/J.Ccr.2009.08.011  0.456
2009 Dibble CC, Asara JM, Manning BD. Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1. Molecular and Cellular Biology. 29: 5657-70. PMID 19720745 DOI: 10.1128/Mcb.00735-09  0.522
2008 Huang J, Dibble CC, Matsuzaki M, Manning BD. The TSC1-TSC2 complex is required for proper activation of mTOR complex 2. Molecular and Cellular Biology. 28: 4104-15. PMID 18411301 DOI: 10.1128/Mcb.00289-08  0.488
2006 Zhang HH, Lipovsky AI, Dibble CC, Sahin M, Manning BD. S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt. Molecular Cell. 24: 185-97. PMID 17052453 DOI: 10.1016/J.Molcel.2006.09.019  0.572
2003 Fan L, Pepicelli CV, Dibble CC, Catbagan W, Zarycki JL, Laciak R, Lamm ML, Munoz A, Brantley Trasher J, Bushman W. Hedgehog signaling, an embryonic signaling pathway, promotes prostate xenograft tumor growth European Urology Supplements. 2: 86. DOI: 10.1016/S1569-9056(03)90447-7  0.399
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