Suzanne J. Baker, Ph.D. - Publications

Affiliations: 
Developmental Neurobiology St. Jude Children's Research Hospital, San Francisco, CA, United States 
 University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
PI3K-PTEN pathway, Pediatrics, Gliomas,
Website:
http://www.stjude.org/stjude/v/index.jsp?vgnextoid=a51c6f9523e70110VgnVCM1000001e0215acRCRD&cpsextcurrchannel=1

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jiao F, Li Z, He C, Xu W, Yang G, Liu T, Shen H, Cai J, Anastas JN, Mao Y, Yu Y, Lan F, Shi YG, Jones C, Xu Y, ... Baker SJ, et al. RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. Science Advances. 6: eaba2113. PMID 32832624 DOI: 10.1126/Sciadv.Aba2113  0.337
2020 Smith KS, Xu K, Mercer KS, Boop F, Klimo P, DeCupyere M, Grenet J, Robinson S, Dunphy P, Baker SJ, Ellison DW, Merchant TE, Upadayaya SA, Gajjar A, Wu G, et al. Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource. Acta Neuropathologica. PMID 32519082 DOI: 10.1007/S00401-020-02171-5  0.346
2020 Slyper M, Porter CBM, Ashenberg O, Waldman J, Drokhlyansky E, Wakiro I, Smillie C, Smith-Rosario G, Wu J, Dionne D, Vigneau S, Jané-Valbuena J, Tickle TL, Napolitano S, Su MJ, ... ... Baker SJ, et al. A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors. Nature Medicine. 26: 792-802. PMID 32405060 DOI: 10.1038/S41591-020-0844-1  0.329
2020 Chiang J, Diaz AK, Makepeace L, Li X, Han Y, Li Y, Klimo P, Boop FA, Baker SJ, Gajjar A, Merchant TE, Ellison DW, Broniscer A, Patay Z, Tinkle CL. Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG. Acta Neuropathologica Communications. 8: 57. PMID 32326973 DOI: 10.1186/S40478-020-00930-9  0.341
2020 Dunphy PS, Xu K, Gentry DT, He C, Mercer K, Zhu X, Smith K, Gudenas B, Robinson S, Zhang J, Kasper LH, Kwon C, Hover LD, Larson JD, Twarog N, ... ... Baker SJ, et al. Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors Tumor Biology. DOI: 10.1158/1538-7445.Am2020-6144  0.537
2019 Kasper LH, Baker SJ. Emerging Functions of Histone H3 Mutations in Paediatric Diffuse High-Grade Gliomas. Neuropathology and Applied Neurobiology. PMID 31859390 DOI: 10.1111/Nan.12591  0.344
2019 Wang H, Diaz AK, Shaw TI, Li Y, Niu M, Cho JH, Paugh BS, Zhang Y, Sifford J, Bai B, Wu Z, Tan H, Zhou S, Hover LD, Tillman HS, ... ... Baker SJ, et al. Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes. Nature Communications. 10: 3718. PMID 31420543 DOI: 10.1038/S41467-019-11661-4  0.414
2019 Patel YT, Davis A, Baker SJ, Campagne O, Stewart CF. CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors. Cancer Chemotherapy and Pharmacology. PMID 31079218 DOI: 10.1007/S00280-019-03864-9  0.336
2019 Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, ... ... Baker SJ, et al. H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo. Acta Neuropathologica. PMID 30770999 DOI: 10.1007/S00401-019-01975-4  0.419
2019 Larson JD, Baker SJ. Engineering Inducible Knock-In Mice to Model Oncogenic Brain Tumor Mutations from Endogenous Loci. Methods in Molecular Biology (Clifton, N.J.). 1869: 207-230. PMID 30324526 DOI: 10.1007/978-1-4939-8805-1_18  0.404
2019 Pribyl LJ, Downing SM, Camacho CV, Larson JD, Baker SJ, McKinnon PJ. Abstract LB-289: Genomic instability and the development of high-grade gliomas Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Lb-289  0.377
2018 Larson JD, Kasper LH, Paugh BS, Jin H, Wu G, Kwon CH, Fan Y, Shaw TI, Silveira AB, Qu C, Xu R, Zhu X, Zhang J, Russell HR, Peters JL, ... ... Baker SJ, et al. Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Cancer Cell. PMID 30595505 DOI: 10.1016/J.Ccell.2018.11.015  0.566
2018 Xu K, Ding L, Chang TC, Shao Y, Chiang J, Mulder H, Wang S, Shaw TI, Wen J, Hover L, McLeod C, Wang YD, Easton J, Rusch M, Dalton J, ... ... Baker SJ, et al. Structure and evolution of double minutes in diagnosis and relapse brain tumors. Acta Neuropathologica. PMID 30267146 DOI: 10.1007/S00401-018-1912-1  0.392
2018 Larson J, Kasper L, Paugh B, Wu G, Jin H, Fan Y, Kwon C, Finkelstein D, Silveira A, Xu R, Zhu X, Zhang J, Xu B, Russell H, McKinnon P, ... ... Baker S, et al. DIPG-68. ONCOGENIC MECHANISMS OF H3.3 K27M IN A SPONTANEOUS DIPG MOUSE MODEL Neuro-Oncology. 20: i63-i63. DOI: 10.1093/Neuonc/Noy059.161  0.497
2017 Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, ... ... Baker SJ, et al. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. Cancer Cell. PMID 28966033 DOI: 10.1016/J.Ccell.2017.08.017  0.373
2017 Hover L, Diaz A, Orr B, Baker S. TMOD-07. NTRK3 GENE FUSIONS DRIVE TUMORIGENESIS IN NOVEL MODELS OF PEDIATRIC HIGH GRADE GLIOMA Neuro-Oncology. 19: iv49-iv50. DOI: 10.1093/Neuonc/Nox083.206  0.306
2016 Zhu G, Rankin SL, Larson JD, Zhu X, Chow LM, Qu C, Zhang J, Ellison DW, Baker SJ. PTEN signaling in the postnatal perivascular progenitor niche drives medulloblastoma formation. Cancer Research. PMID 27815386 DOI: 10.1158/0008-5472.Can-16-1991  0.678
2016 Jones C, Karajannis MA, Jones DT, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, et al. Pediatric high-grade glioma: biologically and clinically in need of new thinking. Neuro-Oncology. PMID 27282398 DOI: 10.1093/Neuonc/Now101  0.304
2016 Zhu G, Baker SJ. Detecting PTEN and PI3K Signaling in Brain. Methods in Molecular Biology (Clifton, N.J.). 1388: 53-62. PMID 27033070 DOI: 10.1007/978-1-4939-3299-3_5  0.642
2016 Qaddoumi I, Orisme W, Wen J, Santiago T, Gupta K, Dalton JD, Tang B, Haupfear K, Punchihewa C, Easton J, Mulder H, Boggs K, Shao Y, Rusch M, Becksfort J, ... ... Baker SJ, et al. Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology. Acta Neuropathologica. PMID 26810070 DOI: 10.1007/S00401-016-1539-Z  0.363
2016 Larson JD, Silveira AB, Kasper LH, Diaz AK, Zhu X, Baker SJ. Abstract IA15: The unique genomic and epigenomic landscape of pediatric high-grade glioma Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Ia15  0.392
2016 Larson JD, Kasper LH, Russell HR, Qu C, Zhu X, McKinnon PJ, Baker SJ. Abstract B01: Biological consequences of histone mutations in the mammalian brain Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B01  0.409
2016 Larson J, Kasper L, Wu G, Fan Y, Zhu X, Paugh B, Qu C, Russell H, McKinnon P, Ellison D, Zhang J, Baker S. HG-116ONCOGENIC ACTIVITY OF HISTONE MUTATIONS IN THE MAMMALIAN BRAIN Neuro-Oncology. 18: iii75.2-iii75. DOI: 10.1093/Neuonc/Now073.112  0.332
2015 Baker SJ, Ellison DW, Gutmann DH. Pediatric gliomas as neurodevelopmental disorders. Glia. PMID 26638183 DOI: 10.1002/Glia.22945  0.359
2015 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ. Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 4. PMID 26633882 DOI: 10.7554/Elife.12703  0.377
2015 Zhai Y, Kuick R, Tipton C, Wu R, Sessine M, Wang Z, Baker SJ, Fearon ER, Cho KR. Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival. The Journal of Pathology. PMID 26279473 DOI: 10.1002/Path.4599  0.373
2015 Joshi A, Miller C, Baker SJ, Ellenson LH. Activated mutant p110α causes endometrial carcinoma in the setting of biallelic Pten deletion. The American Journal of Pathology. 185: 1104-13. PMID 25698082 DOI: 10.1016/J.Ajpath.2014.12.019  0.377
2015 Larson JD, Silveira AB, Kasper LH, Russell HR, Qu C, McKinnon PJ, Baker SJ. Abstract IA14: The unique genomic landscape of pediatric high-grade glioma Brain. 75. DOI: 10.1158/1538-7445.Brain15-Ia14  0.388
2015 Silveira AB, Zhu X, Qu C, Baker S. Abstract B06: Knock-down of H3.3 K27M mutant protein in DIPG cells delays, but does not abrogate, tumor growth in vivo Brain. 75. DOI: 10.1158/1538-7445.Brain15-B06  0.313
2015 Larson J, Kasper L, Russell H, Qu C, Zhu X, McKinnon P, Baker S. PM-13 * BIOLOGICAL CONSEQUENCES OF HISTONE MUTATIONS IN THE MAMMALIAN BRAIN Neuro-Oncology. 17: iii34-iii34. DOI: 10.1093/Neuonc/Nov061.135  0.406
2014 Jones C, Baker SJ. Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma. Nature Reviews. Cancer. 14. PMID 25230881 DOI: 10.1038/Nrc3811  0.349
2014 Diaz AK, Baker SJ. The genetic signatures of pediatric high-grade glioma: no longer a one-act play. Seminars in Radiation Oncology. 24: 240-7. PMID 25219808 DOI: 10.1016/J.Semradonc.2014.06.003  0.4
2014 Huether R, Dong L, Chen X, Wu G, Parker M, Wei L, Ma J, Edmonson MN, Hedlund EK, Rusch MC, Shurtleff SA, Mulder HL, Boggs K, Vadordaria B, Cheng J, ... ... Baker SJ, et al. The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes. Nature Communications. 5: 3630. PMID 24710217 DOI: 10.1038/Ncomms4630  0.346
2014 Wetmore C, Broniscer A, Turner D, Wright KD, Pai-Panandiker A, Kun LE, Ramachandran A, Onar-Thomas A, Huang J, Gajjar AJ, Baker S, Stewart CF. First-in-pediatrics phase I study of crenolanib besylate (CP-868,596-26) administered during and after radiation therapy (RT) in newly diagnosed diffuse intrinsic pontine glioma (DIPG) and recurrent high-grade glioma (HGG). Journal of Clinical Oncology. 32: 10064-10064. DOI: 10.1200/Jco.2014.32.15_Suppl.10064  0.307
2014 Diaz AK, Wu G, Paugh BS, Li Y, Zhu X, Rankin S, Qu C, Chen X, Zhang J, Easton J, Edmonson M, Lu C, Nagahawatte P, Hedlund E, Rusch M, ... ... Baker SJ, et al. Abstract PR03: The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Pr03  0.379
2014 Baker SJ. Abstract IA08: PTEN and PI3K signaling in brain development and disease Cancer Research. 74. DOI: 10.1158/1538-7445.Cansusc14-Ia08  0.399
2014 Misuraca K, Diaz A, Baker S, Becher O. PM-12Pax3 EXPRESSION ENHANCES PDGF-B-INDUCED BRAINSTEM GLIOMAGENESIS AND CHARACTERIZES A SUBSET OF BRAINSTEM GLIOMA Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou268.12  0.396
2013 Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nature Cell Biology. 15: 614-24. PMID 23644469 DOI: 10.1038/Ncb2735  0.321
2013 Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop FA, Lu C, Kandoth C, Ding L, Lee R, ... ... Baker SJ, et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nature Genetics. 45: 602-12. PMID 23583981 DOI: 10.1038/Ng.2611  0.393
2013 Wu R, Baker SJ, Hu TC, Norman KM, Fearon ER, Cho KR. Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer. The American Journal of Pathology. 182: 1391-9. PMID 23499052 DOI: 10.1016/J.Ajpath.2012.12.031  0.373
2013 Larson JD, McEachron TA, Qu C, Zhu X, Diaz AK, Ellison DW, Orr BA, Baker SJ. Abstract A15: Variant histone H3 mutations associate with histone modification, DNA methylation, and gene expression changes in pediatric high-grade gliomas Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A15  0.363
2012 Zhu G, Chow LM, Bayazitov IT, Tong Y, Gilbertson RJ, Zakharenko SS, Solecki DJ, Baker SJ. Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects. Development (Cambridge, England). 139: 3422-31. PMID 22874917 DOI: 10.1242/Dev.083154  0.644
2012 Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, et al. Novel mutations target distinct subgroups of medulloblastoma. Nature. 488: 43-8. PMID 22722829 DOI: 10.1038/Nature11213  0.366
2012 Chow LM, Baker SJ. Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse models. Oncotarget. 3: 67-77. PMID 22287481 DOI: 10.18632/Oncotarget.425  0.331
2012 Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, Zhang J, Gajjar A, Dyer MA, Mullighan CG, Gilbertson RJ, ... ... Baker SJ, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nature Genetics. 44: 251-3. PMID 22286216 DOI: 10.1038/Ng.1102  0.334
2012 Sperow M, Berry RB, Bayazitov IT, Zhu G, Baker SJ, Zakharenko SS. Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration. The Journal of Physiology. 590: 777-92. PMID 22147265 DOI: 10.1113/Jphysiol.2011.220236  0.629
2012 Rankin SL, Zhu G, Baker SJ. Review: insights gained from modelling high-grade glioma in the mouse. Neuropathology and Applied Neurobiology. 38: 254-70. PMID 22035336 DOI: 10.1111/J.1365-2990.2011.01231.X  0.659
2011 Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, et al. Targeted therapy for BRAFV600E malignant astrocytoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7595-604. PMID 22038996 DOI: 10.1158/1078-0432.Ccr-11-1456  0.392
2011 Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, Olson JM, Geyer JR, Chi SN, da Silva NS, Onar-Thomas A, Baker JN, Gajjar A, Ellison DW, Baker SJ. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3999-4006. PMID 21931021 DOI: 10.1200/Jco.2011.35.5677  0.308
2011 Endersby R, Zhu X, Hay N, Ellison DW, Baker SJ. Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model. Cancer Research. 71: 4106-16. PMID 21507933 DOI: 10.1158/0008-5472.Can-10-3597  0.369
2011 Chow LM, Endersby R, Zhu X, Rankin S, Qu C, Zhang J, Broniscer A, Ellison DW, Baker SJ. Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain. Cancer Cell. 19: 305-16. PMID 21397855 DOI: 10.1016/J.Ccr.2011.01.039  0.427
2010 Tatevossian RG, Tang B, Dalton J, Forshew T, Lawson AR, Ma J, Neale G, Shurtleff SA, Bailey S, Gajjar A, Baker SJ, Sheer D, Ellison DW. MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta Neuropathologica. 120: 731-43. PMID 21046410 DOI: 10.1007/S00401-010-0763-1  0.387
2010 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G. Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. Plos Biology. 8. PMID 20808958 DOI: 10.1371/Journal.Pbio.1000460  0.306
2010 Paugh BS, Qu C, Jones C, Liu Z, Adamowicz-Brice M, Zhang J, Bax DA, Coyle B, Barrow J, Hargrave D, Lowe J, Gajjar A, Zhao W, Broniscer A, Ellison DW, ... ... Baker SJ, et al. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 3061-8. PMID 20479398 DOI: 10.1200/Jco.2009.26.7252  0.325
2009 Westmoreland JJ, Wang Q, Bouzaffour M, Baker SJ, Sosa-Pineda B. Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells. Developmental Biology. 334: 285-98. PMID 19635472 DOI: 10.1016/J.Ydbio.2009.07.030  0.327
2009 Chalhoub N, Zhu G, Zhu X, Baker SJ. Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains. Genes & Development. 23: 1619-24. PMID 19605683 DOI: 10.1101/Gad.1799609  0.673
2009 Frappart PO, Lee Y, Russell HR, Chalhoub N, Wang YD, Orii KE, Zhao J, Kondo N, Baker SJ, McKinnon PJ. Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency. Proceedings of the National Academy of Sciences of the United States of America. 106: 1880-5. PMID 19164512 DOI: 10.1073/Pnas.0806882106  0.368
2009 Chalhoub N, Baker SJ. PTEN and the PI3-kinase pathway in cancer. Annual Review of Pathology. 4: 127-50. PMID 18767981 DOI: 10.1146/Annurev.Pathol.4.110807.092311  0.321
2008 Endersby R, Baker SJ. PTEN signaling in brain: neuropathology and tumorigenesis. Oncogene. 27: 5416-30. PMID 18794877 DOI: 10.1038/Onc.2008.239  0.439
2008 Chow LM, Zhang J, Baker SJ. Inducible Cre recombinase activity in mouse mature astrocytes and adult neural precursor cells. Transgenic Research. 17: 919-28. PMID 18483774 DOI: 10.1007/S11248-008-9185-4  0.337
2008 Weber T, Corbett MK, Chow LM, Valentine MB, Baker SJ, Zuo J. Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 781-5. PMID 18178626 DOI: 10.1073/Pnas.0708061105  0.324
2008 Fraser MM, Bayazitov IT, Zakharenko SS, Baker SJ. Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities. Neuroscience. 151: 476-88. PMID 18082964 DOI: 10.1016/J.Neuroscience.2007.10.048  0.368
2007 Torchia EC, Boyd K, Rehg JE, Qu C, Baker SJ. EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice. Molecular and Cellular Biology. 27: 7918-34. PMID 17875932 DOI: 10.1128/Mcb.00099-07  0.401
2006 Kawaguchi T, Yamashita Y, Kanamori M, Endersby R, Bankiewicz KS, Baker SJ, Bergers G, Pieper RO. The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo. Cancer Research. 66: 11331-40. PMID 17145879 DOI: 10.1158/0008-5472.Can-06-1540  0.363
2006 Hayes MP, Wang H, Espinal-Witter R, Douglas W, Solomon GJ, Baker SJ, Ellenson LH. PIK3CA and PTEN mutations in uterine endometrioid carcinoma and complex atypical hyperplasia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5932-5. PMID 17062663 DOI: 10.1158/1078-0432.Ccr-06-1375  0.326
2006 Chow LM, Tian Y, Weber T, Corbett M, Zuo J, Baker SJ. Inducible Cre recombinase activity in mouse cerebellar granule cell precursors and inner ear hair cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2991-8. PMID 16958097 DOI: 10.1002/Dvdy.20948  0.363
2006 Chalhoub N, Kozma SC, Baker SJ. S6k1 is not required for Pten-deficient neuronal hypertrophy. Brain Research. 1100: 32-41. PMID 16777079 DOI: 10.1016/J.Brainres.2006.05.013  0.413
2006 Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/J.Neuron.2006.03.023  0.569
2006 Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/Gene.20197  0.542
2006 Chow LM, Baker SJ. PTEN function in normal and neoplastic growth. Cancer Letters. 241: 184-96. PMID 16412571 DOI: 10.1016/J.Canlet.2005.11.042  0.393
2006 Edwin F, Singh R, Endersby R, Baker SJ, Patel TB. The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation. The Journal of Biological Chemistry. 281: 4816-22. PMID 16371366 DOI: 10.1074/Jbc.M508300200  0.371
2005 Abel TW, Baker SJ, Fraser MM, Tihan T, Nelson JS, Yachnis AT, Bouffard JP, Mena H, Burger PC, Eberhart CG. Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway. Journal of Neuropathology and Experimental Neurology. 64: 341-9. PMID 15835270 DOI: 10.1093/Jnen/64.4.341  0.333
2004 Fraser MM, Zhu X, Kwon CH, Uhlmann EJ, Gutmann DH, Baker SJ. Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo. Cancer Research. 64: 7773-9. PMID 15520182 DOI: 10.1158/0008-5472.Can-04-2487  0.602
2004 Yang CH, Murti A, Baker SJ, Frangou-Lazaridis M, Vartapetian AB, Murti KG, Pfeffer LM. Interferon induces the interaction of prothymosin-alpha with STAT3 and results in the nuclear translocation of the complex. Experimental Cell Research. 298: 197-206. PMID 15242774 DOI: 10.1016/J.Yexcr.2004.04.008  0.331
2004 Baker SJ, McKinnon PJ. Tumour-suppressor function in the nervous system. Nature Reviews. Cancer. 4: 184-96. PMID 14993900 DOI: 10.1038/Nrc1297  0.348
2003 Kwon CH, Zhu X, Zhang J, Baker SJ. mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 12923-8. PMID 14534328 DOI: 10.1073/Pnas.2132711100  0.579
2003 Calhoun ES, Jones JB, Ashfaq R, Adsay V, Baker SJ, Valentine V, Hempen PM, Hilgers W, Yeo CJ, Hruban RH, Kern SE. BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets. The American Journal of Pathology. 163: 1255-60. PMID 14507635 DOI: 10.1016/S0002-9440(10)63485-2  0.355
2001 Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nature Genetics. 29: 404-11. PMID 11726927 DOI: 10.1038/Ng781  0.719
2001 Zhu X, Kwon CH, Schlosshauer PW, Ellenson LH, Baker SJ. PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells. Cancer Research. 61: 4569-75. PMID 11389092  0.497
2001 Knoop LL, Baker SJ. EWS/FLI Alters 5′-Splice Site Selection Journal of Biological Chemistry. 276: 22317-22322. PMID 11301318 DOI: 10.1074/Jbc.M008950200  0.714
2000 Knoop LL, Baker SJ. The splicing factor U1C represses EWS/FLI-mediated transactivation Journal of Biological Chemistry. 275: 24865-24871. PMID 10827180 DOI: 10.1074/Jbc.M001661200  0.713
1999 Jaishankar S, Zhang J, Roussel MF, Baker SJ. Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity Oncogene. 18: 5592-5597. PMID 10523836 DOI: 10.1038/Sj.Onc.1202940  0.372
1993 Abate C, Baker SJ, Lees-Miller SP, Anderson CW, Marshak DR, Curran T. Dimerization and DNA binding alter phosphorylation of Fos and Jun. Proceedings of the National Academy of Sciences of the United States of America. 90: 6766-70. PMID 8341696 DOI: 10.1073/Pnas.90.14.6766  0.323
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