Raul Gainetdinov, Ph.D. - Publications

Affiliations: 
Italian Institute of Technology, Genoa, United States 

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Adinolfi A, Zelli S, Leo D, Carbone C, Mus L, Illiano P, Alleva E, Gainetdinov RR, Adriani W. Behavioral characterization of DAT-KO rats and evidence of asocial-like phenotypes in DAT-HET rats: The potential involvement of norepinephrine system. Behavioural Brain Research. 359: 516-527. PMID 30472113 DOI: 10.1016/j.bbr.2018.11.028  0.44
2018 Leo D, Sukhanov I, Gainetdinov RR. Novel translational rat models of dopamine transporter deficiency. Neural Regeneration Research. 13: 2091-2093. PMID 30323131 DOI: 10.4103/1673-5374.241453  0.44
2018 Lam VM, Mielnik CA, Baimel C, Beerepoot P, Espinoza S, Sukhanov I, Horsfall W, Gainetdinov RR, Borgland SL, Ramsey AJ, Salahpour A. Behavioral Effects of a Potential Novel TAAR1 Antagonist. Frontiers in Pharmacology. 9: 953. PMID 30233365 DOI: 10.3389/fphar.2018.00953  0.72
2018 Espinoza S, Leo D, Sotnikova TD, Shahid M, Kääriäinen TM, Gainetdinov RR. Biochemical and Functional Characterization of the Trace Amine-Associated Receptor 1 (TAAR1) Agonist RO5263397. Frontiers in Pharmacology. 9: 645. PMID 29977204 DOI: 10.3389/fphar.2018.00645  0.76
2018 Schwartz MD, Canales JJ, Zucchi R, Espinoza S, Sukhanov I, Gainetdinov RR. Trace amine-associated receptor 1: a multimodal therapeutic target for neuropsychiatric diseases. Expert Opinion On Therapeutic Targets. PMID 29798691 DOI: 10.1080/14728222.2018.1480723  0.44
2018 Aleksandrov AA, Knyazeva VM, Volnova AB, Dmitrieva ES, Korenkova O, Espinoza S, Gerasimov A, Gainetdinov RR. Identification of TAAR5 Agonist Activity of Alpha-NETA and Its Effect on Mismatch Negativity Amplitude in Awake Rats. Neurotoxicity Research. PMID 29713997 DOI: 10.1007/s12640-018-9902-6  0.44
2018 Cinque S, Zoratto F, Poleggi A, Leo D, Cerniglia L, Cimino S, Tambelli R, Alleva E, Gainetdinov RR, Laviola G, Adriani W. Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia. Frontiers in Psychiatry. 9: 43. PMID 29520239 DOI: 10.3389/fpsyt.2018.00043  0.44
2018 Guariento S, Tonelli M, Espinoza S, Gerasimov AS, Gainetdinov RR, Cichero E. Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists. European Journal of Medicinal Chemistry. 146: 171-184. PMID 29407948 DOI: 10.1016/j.ejmech.2018.01.059  0.44
2018 Adinolfi A, Carbone C, Leo D, Gainetdinov RR, Laviola G, Adriani W. Novelty-related behavior of young and adult DAT-KO rats: implication for cognitive and emotional phenotypic patterns. Genes, Brain, and Behavior. PMID 29406596 DOI: 10.1111/gbb.12463  0.44
2018 Leo D, Sukhanov I, Zoratto F, Illiano P, Caffino L, Sanna F, Messa G, Emanuele M, Esposito A, Dorofeikova M, Budygin EA, Mus L, Efimova EE, Niello M, Espinoza S, ... ... Gainetdinov RR, et al. PRONOUNCED HYPERACTIVITY, COGNITIVE DYSFUNCTIONS AND BDNF DYSREGULATION IN DOPAMINE TRANSPORTER KNOCKOUT RATS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29348190 DOI: 10.1523/JNEUROSCI.1931-17.2018  0.76
2017 Maggi S, Balzani E, Lassi G, Garcia-Garcia C, Plano A, Espinoza S, Mus L, Tinarelli F, Nolan PM, Gainetdinov RR, Balci F, Nieus T, Tucci V. The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis. Scientific Reports. 7: 17765. PMID 29259298 DOI: 10.1038/s41598-017-18130-2  0.44
2017 Bono F, Savoia P, Guglielmi A, Gennarelli M, Piovani G, Sigala S, Leo D, Espinoza S, Gainetdinov RR, Devoto P, Spano P, Missale C, Fiorentini C. Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons. Molecular Neurobiology. PMID 28092083 DOI: 10.1007/s12035-016-0376-3  0.44
2016 Polanco MJ, Parodi S, Piol D, Stack C, Chivet M, Contestabile A, Miranda HC, Lievens PM, Espinoza S, Jochum T, Rocchi A, Grunseich C, Gainetdinov RR, Cato AC, Lieberman AP, et al. Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy. Science Translational Medicine. 8: 370ra181. PMID 28003546 DOI: 10.1126/scitranslmed.aaf9526  0.44
2016 Tonelli M, Espinoza S, Gainetdinov RR, Cichero E. Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies. European Journal of Medicinal Chemistry. PMID 27823885 DOI: 10.1016/j.ejmech.2016.10.058  0.44
2016 Chiellini G, Nesi G, Sestito S, Chiarugi S, Runfola M, Espinoza S, Sabatini M, Bellusci L, Laurino A, Cichero E, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S. Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study. Journal of Medicinal Chemistry. PMID 27731647 DOI: 10.1021/acs.jmedchem.6b01092  0.44
2016 Illiano P, Lanzo A, Leo D, Paglione M, Zampi G, Gainetdinov RR, Schiavi ED. A Caenorhabditis elegans model to study Dopamine Transporter Deficiency Syndrome. The European Journal of Neuroscience. PMID 27519790 DOI: 10.1111/ejn.13366  0.44
2016 Mikhailova MA, Bass CE, Grinevich VP, Chappell AM, Deal AL, Bonin KD, Weiner JL, Gainetdinov RR, Budygin EA. Optogenetically-induced tonic dopamine release from VTA-nucleus accumbens projections inhibits reward consummatory behaviors. Neuroscience. PMID 27421228 DOI: 10.1016/j.neuroscience.2016.07.006  1
2016 Fox ME, Mikhailova MA, Bass CE, Takmakov P, Gainetdinov RR, Budygin EA, Wightman RM. Cross-hemispheric dopamine projections have functional significance. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298371 DOI: 10.1073/pnas.1603629113  1
2016 Efimova EV, Gainetdinov RR, Budygin EA, Sotnikova TD. Dopamine transporter mutant animals: a translational perspective. Journal of Neurogenetics. 30: 5-15. PMID 27276191 DOI: 10.3109/01677063.2016.1144751  1
2016 Homberg JR, Kyzar EJ, Scattoni ML, Norton WH, Pittman J, Gaikwad S, Nguyen M, Poudel MK, Ullmann JF, Diamond DM, Kaluyeva AA, Parker MO, Brown RE, Song C, Gainetdinov RR, et al. Genetic and environmental modulation of neurodevelopmental disorders: translational insights from labs to beds. Brain Research Bulletin. PMID 27113433 DOI: 10.1016/j.brainresbull.2016.04.015  1
2016 Homberg JR, Kyzar EJ, Nguyen M, Norton WH, Pittman J, Poudel MK, Gaikwad S, Nakamura S, Koshiba M, Yamanouchi H, Scattoni ML, Ullman JF, Diamond DM, Kaluyeva AA, Parker MO, ... ... Gainetdinov RR, et al. Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models. Neuroscience and Biobehavioral Reviews. PMID 27048961 DOI: 10.1016/j.neubiorev.2016.03.013  1
2016 Cichero E, Espinoza S, Tonelli M, Franchini S, Gerasimov AS, Sorbi C, Gainetdinov RR, Brasili L, Fossa P. A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists Medchemcomm. 7: 353-364. DOI: 10.1039/c5md00490j  1
2015 Ilya S, Lucia C, Evgeniya EV, Stefano E, Tatiana SD, Luigi C, Fabio F, Raul GR. Increased context-dependent conditioning to amphetamine in mice lacking taar1. Pharmacological Research. PMID 26640076 DOI: 10.1016/j.phrs.2015.11.002  1
2015 Colasante G, Lignani G, Rubio A, Medrihan L, Yekhlef L, Sessa A, Massimino L, Giannelli SG, Sacchetti S, Caiazzo M, Leo D, Alexopoulou D, Dell'Anno MT, Ciabatti E, Orlando M, ... ... Gainetdinov RR, et al. Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming. Cell Stem Cell. PMID 26526726 DOI: 10.1016/j.stem.2015.09.002  1
2015 Lam VM, Espinoza S, Gerasimov AS, Gainetdinov RR, Salahpour A. In-vivo pharmacology of Trace-Amine Associated Receptor 1. European Journal of Pharmacology. PMID 26093041 DOI: 10.1016/j.ejphar.2015.06.026  1
2015 Chiellini G, Nesi G, Digiacomo M, Malvasi R, Espinoza S, Sabatini M, Frascarelli S, Laurino A, Cichero E, Macchia M, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S. Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists. Journal of Medicinal Chemistry. 58: 5096-107. PMID 26010728 DOI: 10.1021/acs.jmedchem.5b00526  1
2015 Urs NM, Bido S, Peterson SM, Daigle TL, Bass CE, Gainetdinov RR, Bezard E, Caron MG. Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: E2517-26. PMID 25918399 DOI: 10.1073/pnas.1502740112  1
2015 Cotter R, Pei Y, Mus L, Harmeier A, Gainetdinov RR, Hoener MC, Canales JJ. The trace amine-associated receptor 1 modulates methamphetamine's neurochemical and behavioral effects. Frontiers in Neuroscience. 9: 39. PMID 25762894 DOI: 10.3389/fnins.2015.00039  1
2015 Espinoza S, Lignani G, Caffino L, Maggi S, Sukhanov I, Leo D, Mus L, Emanuele M, Ronzitti G, Harmeier A, Medrihan L, Sotnikova TD, Chieregatti E, Hoener MC, Benfenati F, ... ... Gainetdinov RR, et al. TAAR1 Modulates Cortical Glutamate NMDA Receptor Function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2217-27. PMID 25749299 DOI: 10.1038/npp.2015.65  1
2015 Espinoza S, Ghisi V, Emanuele M, Leo D, Sukhanov I, Sotnikova TD, Chieregatti E, Gainetdinov RR. Postsynaptic D2 dopamine receptor supersensitivity in the striatum of mice lacking TAAR1. Neuropharmacology. 93: 308-13. PMID 25721394 DOI: 10.1016/j.neuropharm.2015.02.010  1
2015 Beaulieu JM, Espinoza S, Gainetdinov RR. Dopamine receptors - IUPHAR Review 13. British Journal of Pharmacology. 172: 1-23. PMID 25671228 DOI: 10.1111/bph.12906  1
2015 Gurevich EV, Premont RT, Gainetdinov RR. G protein-coupled receptor kinases: from molecules to diseases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 361-4. PMID 25649814 DOI: 10.1096/fj.14-263657ufm  1
2015 Masoud ST, Vecchio LM, Bergeron Y, Hossain MM, Nguyen LT, Bermejo MK, Kile B, Sotnikova TD, Siesser WB, Gainetdinov RR, Wightman RM, Caron MG, Richardson JR, Miller GW, Ramsey AJ, et al. Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits. Neurobiology of Disease. 74: 66-75. PMID 25447236 DOI: 10.1016/j.nbd.2014.10.016  1
2014 Ronzitti G, Bucci G, Emanuele M, Leo D, Sotnikova TD, Mus LV, Soubrane CH, Dallas ML, Thalhammer A, Cingolani LA, Mochida S, Gainetdinov RR, Stephens GJ, Chieregatti E. Exogenous α-synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10603-15. PMID 25100594 DOI: 10.1523/JNEUROSCI.0608-14.2014  1
2014 Dell'Anno MT, Caiazzo M, Leo D, Dvoretskova E, Medrihan L, Colasante G, Giannelli S, Theka I, Russo G, Mus L, Pezzoli G, Gainetdinov RR, Benfenati F, Taverna S, Dityatev A, et al. Remote control of induced dopaminergic neurons in parkinsonian rats. The Journal of Clinical Investigation. 124: 3215-29. PMID 24937431 DOI: 10.1172/JCI74664  1
2014 Sukhanov I, Espinoza S, Yakovlev DS, Hoener MC, Sotnikova TD, Gainetdinov RR. TAAR1-dependent effects of apomorphine in mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1683-93. PMID 24925023 DOI: 10.1017/S1461145714000509  1
2014 Cichero E, Espinoza S, Franchini S, Guariento S, Brasili L, Gainetdinov RR, Fossa P. Further insights into the pharmacology of the human trace amine-associated receptors: discovery of novel ligands for TAAR1 by a virtual screening approach. Chemical Biology & Drug Design. 84: 712-20. PMID 24894156 DOI: 10.1111/cbdd.12367  1
2014 Steinkellner T, Mus L, Eisenrauch B, Constantinescu A, Leo D, Konrad L, Rickhag M, Sørensen G, Efimova EV, Kong E, Willeit M, Sotnikova TD, Kudlacek O, Gether U, Freissmuth M, ... ... Gainetdinov RR, et al. In vivo amphetamine action is contingent on αCaMKII. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2681-93. PMID 24871545 DOI: 10.1038/npp.2014.124  1
2014 Daigle TL, Ferris MJ, Gainetdinov RR, Sotnikova TD, Urs NM, Jones SR, Caron MG. Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2450-62. PMID 24776686 DOI: 10.1038/npp.2014.97  1
2014 Ferris MJ, Milenkovic M, Liu S, Mielnik CA, Beerepoot P, John CE, España RA, Sotnikova TD, Gainetdinov RR, Borgland SL, Jones SR, Ramsey AJ. Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling. The European Journal of Neuroscience. 40: 2255-63. PMID 24754704 DOI: 10.1111/ejn.12594  1
2014 Pei Y, Lee J, Leo D, Gainetdinov RR, Hoener MC, Canales JJ. Activation of the trace amine-associated receptor 1 prevents relapse to cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2299-308. PMID 24722355 DOI: 10.1038/npp.2014.88  1
2014 Cagniard B, Sotnikova TD, Gainetdinov RR, Zhuang X. The dopamine transporter expression level differentially affects responses to cocaine and amphetamine. Journal of Neurogenetics. 28: 112-21. PMID 24673634 DOI: 10.3109/01677063.2014.908191  1
2014 Marion S, Urs NM, Peterson SM, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Dopamine D2 receptor relies upon PPM/PP2C protein phosphatases to dephosphorylate huntingtin protein. The Journal of Biological Chemistry. 289: 11715-24. PMID 24619418 DOI: 10.1074/jbc.M113.544312  1
2014 Leo D, Mus L, Espinoza S, Hoener MC, Sotnikova TD, Gainetdinov RR. Taar1-mediated modulation of presynaptic dopaminergic neurotransmission: role of D2 dopamine autoreceptors. Neuropharmacology. 81: 283-91. PMID 24565640 DOI: 10.1016/j.neuropharm.2014.02.007  1
2014 Lavoie J, Illiano P, Sotnikova TD, Gainetdinov RR, Beaulieu JM, Hébert M. The electroretinogram as a biomarker of central dopamine and serotonin: potential relevance to psychiatric disorders. Biological Psychiatry. 75: 479-86. PMID 23305992 DOI: 10.1016/j.biopsych.2012.11.024  1
2013 Medvedev IO, Ramsey AJ, Masoud ST, Bermejo MK, Urs N, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Salahpour A. D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18125-33. PMID 24227722 DOI: 10.1523/JNEUROSCI.2382-13.2013  1
2013 Lignani G, Ferrea E, Difato F, Amarù J, Ferroni E, Lugarà E, Espinoza S, Gainetdinov RR, Baldelli P, Benfenati F. Long-term optical stimulation of channelrhodopsin-expressing neurons to study network plasticity. Frontiers in Molecular Neuroscience. 6: 22. PMID 23970852 DOI: 10.3389/fnmol.2013.00022  1
2013 Leo D, Gainetdinov RR. Transgenic mouse models for ADHD. Cell and Tissue Research. 354: 259-71. PMID 23681253 DOI: 10.1007/s00441-013-1639-1  1
2013 Theka I, Caiazzo M, Dvoretskova E, Leo D, Ungaro F, Curreli S, Managò F, Dell'Anno MT, Pezzoli G, Gainetdinov RR, Dityatev A, Broccoli V. Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors. Stem Cells Translational Medicine. 2: 473-9. PMID 23658252 DOI: 10.5966/sctm.2012-0133  1
2013 Siesser WB, Sachs BD, Ramsey AJ, Sotnikova TD, Beaulieu JM, Zhang X, Caron MG, Gainetdinov RR. Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. Acs Chemical Neuroscience. 4: 84-8. PMID 23336047 DOI: 10.1021/cn300127h  1
2013 Espinoza S, Masri B, Salahpour A, Gainetdinov RR. BRET approaches to characterize dopamine and TAAR1 receptor pharmacology and signaling. Methods in Molecular Biology (Clifton, N.J.). 964: 107-22. PMID 23296781 DOI: 10.1007/978-1-62703-251-3_8  1
2013 Cichero E, Espinoza S, Gainetdinov RR, Brasili L, Fossa P. Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies. Chemical Biology & Drug Design. 81: 509-16. PMID 22883051 DOI: 10.1111/cbdd.12018  1
2013 Sotnikova TD, Espinoza S, Gainetdinov RR. Trace Amines and Their Receptors: New Opportunities for Modulation of Brain Dopaminergic Functions Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 92-93. DOI: 10.1016/B978-0-12-800044-1.00079-9  1
2012 Salahpour A, Espinoza S, Masri B, Lam V, Barak LS, Gainetdinov RR. BRET biosensors to study GPCR biology, pharmacology, and signal transduction. Frontiers in Endocrinology. 3: 105. PMID 22952466 DOI: 10.3389/fendo.2012.00105  1
2012 Revel FG, Moreau JL, Gainetdinov RR, Ferragud A, Velázquez-Sánchez C, Sotnikova TD, Morairty SR, Harmeier A, Groebke Zbinden K, Norcross RD, Bradaia A, Kilduff TS, Biemans B, Pouzet B, Caron MG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biological Psychiatry. 72: 934-42. PMID 22705041 DOI: 10.1016/j.biopsych.2012.05.014  1
2012 Espinoza S, Manago F, Leo D, Sotnikova TD, Gainetdinov RR. Role of catechol-O-methyltransferase (COMT)-dependent processes in Parkinson's disease and L-DOPA treatment. Cns & Neurological Disorders Drug Targets. 11: 251-63. PMID 22483291  1
2012 Managò F, Espinoza S, Salahpour A, Sotnikova TD, Caron MG, Premont RT, Gainetdinov RR. The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment. Scientific Reports. 2: 301. PMID 22393477 DOI: 10.1038/srep00301  1
2012 Meck WH, Cheng RK, MacDonald CJ, Gainetdinov RR, Caron MG, Cevik MÖ. Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice. Neuropharmacology. 62: 1221-9. PMID 21296093 DOI: 10.1016/j.neuropharm.2011.01.042  1
2011 Guzman MS, De Jaeger X, Raulic S, Souza IA, Li AX, Schmid S, Menon RS, Gainetdinov RR, Caron MG, Bartha R, Prado VF, Prado MA. Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. Plos Biology. 9: e1001194. PMID 22087075 DOI: 10.1371/journal.pbio.1001194  1
2011 Beaulieu JM, Del'guidice T, Sotnikova TD, Lemasson M, Gainetdinov RR. Beyond cAMP: The Regulation of Akt and GSK3 by Dopamine Receptors. Frontiers in Molecular Neuroscience. 4: 38. PMID 22065948 DOI: 10.3389/fnmol.2011.00038  0.76
2011 Herrmann R, Heflin SJ, Hammond T, Lee B, Wang J, Gainetdinov RR, Caron MG, Eggers ED, Frishman LJ, McCall MA, Arshavsky VY. Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA. Neuron. 72: 101-10. PMID 21982372 DOI: 10.1016/j.neuron.2011.07.030  1
2011 Caiazzo M, Dell'Anno MT, Dvoretskova E, Lazarevic D, Taverna S, Leo D, Sotnikova TD, Menegon A, Roncaglia P, Colciago G, Russo G, Carninci P, Pezzoli G, Gainetdinov RR, Gustincich S, et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature. 476: 224-7. PMID 21725324 DOI: 10.1038/nature10284  1
2011 Espinoza S, Salahpour A, Masri B, Sotnikova TD, Messa M, Barak LS, Caron MG, Gainetdinov RR. Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor. Molecular Pharmacology. 80: 416-25. PMID 21670104 DOI: 10.1124/mol.111.073304  1
2011 Revel FG, Moreau JL, Gainetdinov RR, Bradaia A, Sotnikova TD, Mory R, Durkin S, Zbinden KG, Norcross R, Meyer CA, Metzler V, Chaboz S, Ozmen L, Trube G, Pouzet B, et al. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8485-90. PMID 21525407 DOI: 10.1073/pnas.1103029108  1
2011 Beaulieu JM, Gainetdinov RR. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacological Reviews. 63: 182-217. PMID 21303898 DOI: 10.1124/pr.110.002642  1
2011 Omenetti A, Yang L, Gainetdinov RR, Guy CD, Choi SS, Chen W, Caron MG, Diehl AM. Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G303-15. PMID 21071507 DOI: 10.1152/ajpgi.00368.2010  1
2011 Zhang X, Nicholls PJ, Laje G, Sotnikova TD, Gainetdinov RR, Albert PR, Rajkowska G, Stockmeier CA, Speer MC, Steffens DC, Austin MC, McMahon FJ, Krishnan KR, Garcia-Blanco MA, Caron MG. A functional alternative splicing mutation in human tryptophan hydroxylase-2. Molecular Psychiatry. 16: 1169-76. PMID 20856248 DOI: 10.1038/mp.2010.99  1
2010 Gainetdinov RR. Strengths and limitations of genetic models of ADHD. Attention Deficit and Hyperactivity Disorders. 2: 21-30. PMID 21432587 DOI: 10.1007/s12402-010-0021-3  1
2010 Sotnikova TD, Beaulieu JM, Espinoza S, Masri B, Zhang X, Salahpour A, Barak LS, Caron MG, Gainetdinov RR. The dopamine metabolite 3-methoxytyramine is a neuromodulator. Plos One. 5: e13452. PMID 20976142 DOI: 10.1371/journal.pone.0013452  1
2010 Siesser WB, Zhang X, Jacobsen JP, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice. Neuroscience Letters. 481: 6-11. PMID 20600620 DOI: 10.1016/j.neulet.2010.06.035  1
2010 Dzirasa K, Phillips HW, Sotnikova TD, Salahpour A, Kumar S, Gainetdinov RR, Caron MG, Nicolelis MA. Noradrenergic control of cortico-striato-thalamic and mesolimbic cross-structural synchrony. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6387-97. PMID 20445065 DOI: 10.1523/JNEUROSCI.0764-10.2010  1
2010 Caron MG, Gainetdinov RR. Role of Dopamine Transporters in Neuronal Homeostasis Dopamine Handbook. DOI: 10.1093/acprof:oso/9780195373035.003.0007  1
2010 Sotnikova TD, Gainetdinov RR. Octopamine and Other Monoamines in Invertebrates Encyclopedia of Neuroscience. 9-15. DOI: 10.1016/B978-008045046-9.01158-X  1
2009 Xu TX, Sotnikova TD, Liang C, Zhang J, Jung JU, Spealman RD, Gainetdinov RR, Yao WD. Hyperdopaminergic tone erodes prefrontal long-term potential via a D2 receptor-operated protein phosphatase gate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14086-99. PMID 19906957 DOI: 10.1523/JNEUROSCI.0974-09.2009  1
2009 Dzirasa K, Ramsey AJ, Takahashi DY, Stapleton J, Potes JM, Williams JK, Gainetdinov RR, Sameshima K, Caron MG, Nicolelis MA. Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8215-24. PMID 19553461 DOI: 10.1523/JNEUROSCI.1773-09.2009  1
2009 Raehal KM, Schmid CL, Medvedev IO, Gainetdinov RR, Premont RT, Bohn LM. Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6. Drug and Alcohol Dependence. 104: 187-96. PMID 19497686 DOI: 10.1016/j.drugalcdep.2009.04.011  1
2009 Sotnikova TD, Caron MG, Gainetdinov RR. Trace amine-associated receptors as emerging therapeutic targets. Molecular Pharmacology. 76: 229-35. PMID 19389919 DOI: 10.1124/mol.109.055970  1
2009 Dzirasa K, Santos LM, Ribeiro S, Stapleton J, Gainetdinov RR, Caron MG, Nicolelis MA. Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep. Plos One. 4: e5238. PMID 19381303 DOI: 10.1371/journal.pone.0005238  1
2009 Ghisi V, Ramsey AJ, Masri B, Gainetdinov RR, Caron MG, Salahpour A. Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. Cellular Signalling. 21: 87-94. PMID 18929645 DOI: 10.1016/j.cellsig.2008.09.011  1
2009 Beaulieu JM, Gainetdinov RR, Caron MG. Akt/GSK3 signaling in the action of psychotropic drugs. Annual Review of Pharmacology and Toxicology. 49: 327-47. PMID 18928402 DOI: 10.1146/annurev.pharmtox.011008.145634  1
2009 de Castro BM, Pereira GS, Magalhães V, Rossato JI, De Jaeger X, Martins-Silva C, Leles B, Lima P, Gomez MV, Gainetdinov RR, Caron MG, Izquierdo I, Cammarota M, Prado VF, Prado MA. Reduced expression of the vesicular acetylcholine transporter causes learning deficits in mice. Genes, Brain, and Behavior. 8: 23-35. PMID 18778400 DOI: 10.1111/j.1601-183X.2008.00439.x  1
2008 Vinuela A, Hallett PJ, Reske-Nielsen C, Patterson M, Sotnikova TD, Caron MG, Gainetdinov RR, Isacson O. Implanted reuptake-deficient or wild-type dopaminergic neurons improve ON L-dopa dyskinesias without OFF-dyskinesias in a rat model of Parkinson's disease. Brain : a Journal of Neurology. 131: 3361-79. PMID 18988638 DOI: 10.1093/brain/awn192  1
2008 Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu JM, Gainetdinov RR, Caron MG. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proceedings of the National Academy of Sciences of the United States of America. 105: 13656-61. PMID 18768802 DOI: 10.1073/pnas.0803522105  1
2008 Sotnikova TD, Zorina OI, Ghisi V, Caron MG, Gainetdinov RR. Trace amine associated receptor 1 and movement control. Parkinsonism & Related Disorders. 14: S99-102. PMID 18585080 DOI: 10.1016/j.parkreldis.2008.04.006  1
2008 Barak LS, Salahpour A, Zhang X, Masri B, Sotnikova TD, Ramsey AJ, Violin JD, Lefkowitz RJ, Caron MG, Gainetdinov RR. Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor. Molecular Pharmacology. 74: 585-94. PMID 18524885 DOI: 10.1124/mol.108.048884  1
2008 de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA. Food reward in the absence of taste receptor signaling. Neuron. 57: 930-41. PMID 18367093 DOI: 10.1016/j.neuron.2008.01.032  1
2008 Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 105: 4405-10. PMID 18347339 DOI: 10.1073/pnas.0707646105  1
2008 Murphy KL, Zhang X, Gainetdinov RR, Beaulieu JM, Caron MG. A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression. The Journal of Biological Chemistry. 283: 13216-24. PMID 18339632 DOI: 10.1074/jbc.M706749200  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. 105: 1333-8. PMID 18212115 DOI: 10.1073/pnas.0711496105  1
2008 Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 132: 125-36. PMID 18191226 DOI: 10.1016/j.cell.2007.11.041  1
2008 Ramsey AJ, Laakso A, Cyr M, Sotnikova TD, Salahpour A, Medvedev IO, Dykstra LA, Gainetdinov RR, Caron MG. Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2701-14. PMID 18185498 DOI: 10.1038/sj.npp.1301663  1
2008 Gainetdinov RR. Dopamine transporter mutant mice in experimental neuropharmacology. Naunyn-Schmiedeberg's Archives of Pharmacology. 377: 301-13. PMID 18057916 DOI: 10.1007/s00210-007-0216-0  1
2008 Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Wetsel WC, Gainetdinov RR, Caron MG. Reply to Belmaker et al.: GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test Proceedings of the National Academy of Sciences of the United States of America. 105: E24. DOI: 10.1073/pnas.0803026105  1
2008 de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis ML, Simon SA. Food Reward in the Absence of Taste Receptor Signaling (DOI:10.1016/j.neuron.2008.01.032) Neuron. 58: 295. DOI: 10.1016/j.neuron.2008.04.003  1
2007 Gainetdinov RR. Mesolimbic dopamine in obesity and diabetes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R601-2. PMID 17596319 DOI: 10.1152/ajpregu.00450.2007  1
2007 Beaulieu JM, Gainetdinov RR, Caron MG. The Akt-GSK-3 signaling cascade in the actions of dopamine. Trends in Pharmacological Sciences. 28: 166-72. PMID 17349698 DOI: 10.1016/j.tips.2007.02.006  1
2007 Premont RT, Gainetdinov RR. Physiological roles of G protein-coupled receptor kinases and arrestins. Annual Review of Physiology. 69: 511-34. PMID 17305472 DOI: 10.1146/annurev.physiol.69.022405.154731  1
2007 Beaulieu JM, Tirotta E, Sotnikova TD, Masri B, Salahpour A, Gainetdinov RR, Borrelli E, Caron MG. Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 881-5. PMID 17251429 DOI: 10.1523/JNEUROSCI.5074-06.2007  1
2007 Costa RM, Gutierrez R, de Araujo IE, Coelho MR, Kloth AD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA. Dopamine levels modulate the updating of tastant values. Genes, Brain, and Behavior. 6: 314-20. PMID 16848782 DOI: 10.1111/j.1601-183X.2006.00257.x  1
2007 Salahpour A, Medvedev IO, Beaulieu JM, Gainetdinov RR, Caron MG. Local knockdown of genes in the brain using small interfering RNA: a phenotypic comparison with knockout animals. Biological Psychiatry. 61: 65-9. PMID 16712807 DOI: 10.1016/j.biopsych.2006.03.020  1
2006 Caron MG, Gainetdinov RR. Dopamine: from pharmacology to molecular biology and back. Wiener Klinische Wochenschrift. 118: 565-8. PMID 17136328 DOI: 10.1007/s00508-006-0735-6  1
2006 Cyr M, Sotnikova TD, Gainetdinov RR, Caron MG. Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2541-3. PMID 17065224 DOI: 10.1096/fj.06-6533fje  1
2006 Costa RM, Lin SC, Sotnikova TD, Cyr M, Gainetdinov RR, Caron MG, Nicolelis MA. Rapid alterations in corticostriatal ensemble coordination during acute dopamine-dependent motor dysfunction. Neuron. 52: 359-69. PMID 17046697 DOI: 10.1016/j.neuron.2006.07.030  1
2006 Dzirasa K, Ribeiro S, Costa R, Santos LM, Lin SC, Grosmark A, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA. Dopaminergic control of sleep-wake states. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10577-89. PMID 17035544 DOI: 10.1523/JNEUROSCI.1767-06.2006  1
2006 Sotnikova TD, Caron MG, Gainetdinov RR. DDD mice, a novel acute mouse model of Parkinson's disease. Neurology. 67: S12-7. PMID 17030735  1
2006 Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. The Journal of Biological Chemistry. 281: 32072-80. PMID 16954211 DOI: 10.1074/jbc.M606062200  1
2006 Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, ... ... Gainetdinov RR, et al. Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron. 51: 601-12. PMID 16950158 DOI: 10.1016/j.neuron.2006.08.005  1
2006 Sasaki A, Sotnikova TD, Gainetdinov RR, Jarvis ED. Social context-dependent singing-regulated dopamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9010-4. PMID 16943558 DOI: 10.1523/JNEUROSCI.1335-06.2006  1
2006 Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter. Cns & Neurological Disorders Drug Targets. 5: 45-56. PMID 16613553 DOI: 10.2174/187152706784111579  1
2006 Zhang X, Beaulieu JM, Gainetdinov RR, Caron MG. Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2. Cellular and Molecular Life Sciences : Cmls. 63: 6-11. PMID 16378243 DOI: 10.1007/s00018-005-5417-4  1
2006 Sotnikova TD, Gainetdinov RR. Chapter 5.1 Microdialysis in genetically altered animals Handbook of Behavioral Neuroscience. 16: 399-417. DOI: 10.1016/S1569-7339(06)16021-X  1
2005 Zhou Z, Peters EJ, Hamilton SP, McMahon F, Thomas C, McGrath PJ, Rush J, Trivedi MH, Charney DS, Roy A, Wisniewski S, Lipsky R, Goldman D, Van Den Bogaert A, De Zutter S, ... ... Gainetdinov RR, et al. Response to Zhang et al. (2005) loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16 [2] (multiple letters) Neuron. 48: 702-706. PMID 16337901 DOI: 10.1016/j.neuron.2005.11.018  1
2005 Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell. 122: 261-73. PMID 16051150 DOI: 10.1016/j.cell.2005.05.012  1
2005 Sotnikova TD, Beaulieu JM, Barak LS, Wetsel WC, Caron MG, Gainetdinov RR. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. Plos Biology. 3: e271. PMID 16050778 DOI: 10.1371/journal.pbio.0030271  1
2005 Medvedev IO, Gainetdinov RR, Sotnikova TD, Bohn LM, Caron MG, Dykstra LA. Characterization of conditioned place preference to cocaine in congenic dopamine transporter knockout female mice. Psychopharmacology. 180: 408-13. PMID 15719221 DOI: 10.1007/s00213-005-2173-y  1
2005 Kim KM, Gainetdinov RR, Laporte SA, Caron MG, Barak LS. G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. The Journal of Biological Chemistry. 280: 12774-80. PMID 15687500 DOI: 10.1074/jbc.M408901200  1
2005 Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KR, Caron MG. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron. 45: 11-6. PMID 15629698 DOI: 10.1016/j.neuron.2004.12.014  1
2004 Sotnikova TD, Budygin EA, Jones SR, Dykstra LA, Caron MG, Gainetdinov RR. Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine. Journal of Neurochemistry. 91: 362-73. PMID 15447669 DOI: 10.1111/j.1471-4159.2004.02721.x  1
2004 Zhang X, Beaulieu JM, Sotnikova TD, Gainetdinov RR, Caron MG. Tryptophan hydroxylase-2 controls brain serotonin synthesis. Science (New York, N.Y.). 305: 217. PMID 15247473 DOI: 10.1126/science.1097540  1
2004 Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG. Desensitization of G protein-coupled receptors and neuronal functions. Annual Review of Neuroscience. 27: 107-44. PMID 15217328 DOI: 10.1146/annurev.neuro.27.070203.144206  1
2004 Budygin EA, Brodie MS, Sotnikova TD, Mateo Y, John CE, Cyr M, Gainetdinov RR, Jones SR. Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine. Proceedings of the National Academy of Sciences of the United States of America. 101: 7781-6. PMID 15136721 DOI: 10.1073/pnas.0401418101  1
2004 Beaulieu JM, Sotnikova TD, Yao WD, Kockeritz L, Woodgett JR, Gainetdinov RR, Caron MG. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. 101: 5099-104. PMID 15044694 DOI: 10.1073/pnas.0307921101  1
2004 Bohn LM, Gainetdinov RR, Caron MG. G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice. Neuromolecular Medicine. 5: 41-50. PMID 15001811 DOI: 10.1385/NMM:5:1:041  1
2004 Yao WD, Gainetdinov RR, Arbuckle MI, Sotnikova TD, Cyr M, Beaulieu JM, Torres GE, Grant SG, Caron MG. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron. 41: 625-38. PMID 14980210 DOI: 10.1016/S0896-6273(04)00048-0  1
2004 Powell SB, Lehmann-Masten VD, Paulus MP, Gainetdinov RR, Caron MG, Geyer MA. MDMA "ecstasy" alters hyperactive and perseverative behaviors in dopamine transporter knockout mice. Psychopharmacology. 173: 310-7. PMID 14747902 DOI: 10.1007/s00213-003-1765-7  1
2004 Barr AM, Lehmann-Masten V, Paulus M, Gainetdinov RR, Caron MG, Geyer MA. The selective serotonin-2A receptor antagonist M100907 reverses behavioral deficits in dopamine transporter knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 221-8. PMID 14603268 DOI: 10.1038/sj.npp.1300343  1
2004 Walker JK, Gainetdinov RR, Feldman DS, McFawn PK, Caron MG, Lefkowitz RJ, Premont RT, Fisher JT. G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L312-9. PMID 14565944 DOI: 10.1152/ajplung.00255.2003  1
2003 Bohn LM, Gainetdinov RR, Sotnikova TD, Medvedev IO, Lefkowitz RJ, Dykstra LA, Caron MG. Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10265-73. PMID 14614085  1
2003 Cyr M, Beaulieu JM, Laakso A, Sotnikova TD, Yao WD, Bohn LM, Gainetdinov RR, Caron MG. Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 100: 11035-40. PMID 12958210 DOI: 10.1073/pnas.1831768100  1
2003 Miyakawa T, Leiter LM, Gerber DJ, Gainetdinov RR, Sotnikova TD, Zeng H, Caron MG, Tonegawa S. Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 100: 8987-92. PMID 12851457 DOI: 10.1073/pnas.1432926100  1
2003 Gainetdinov RR, Bohn LM, Sotnikova TD, Cyr M, Laakso A, Macrae AD, Torres GE, Kim KM, Lefkowitz RJ, Caron MG, Premont RT. Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice. Neuron. 38: 291-303. PMID 12718862 DOI: 10.1016/S0896-6273(03)00192-2  1
2003 Phillips PE, Johns JM, Lubin DA, Budygin EA, Gainetdinov RR, Lieberman JA, Wightman RM. Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine. Brain Research. 961: 63-72. PMID 12535777 DOI: 10.1016/S0006-8993(02)03840-4  1
2003 Torres GE, Gainetdinov RR, Caron MG. Plasma membrane monoamine transporters: structure, regulation and function. Nature Reviews. Neuroscience. 4: 13-25. PMID 12511858 DOI: 10.1038/nrn1008  1
2003 Gainetdinov RR, Caron MG. Monoamine transporters: from genes to behavior. Annual Review of Pharmacology and Toxicology. 43: 261-84. PMID 12359863 DOI: 10.1146/annurev.pharmtox.43.050802.112309  1
2002 Laakso A, Mohn AR, Gainetdinov RR, Caron MG. Experimental genetic approaches to addiction. Neuron. 36: 213-28. PMID 12383778 DOI: 10.1016/S0896-6273(02)00972-8  1
2002 Gainetdinov RR, Sotnikova TD, Caron MG. Monoamine transporter pharmacology and mutant mice. Trends in Pharmacological Sciences. 23: 367-73. PMID 12377578 DOI: 10.1016/S0165-6147(02)02044-8  1
2002 Joseph JD, Wang YM, Miles PR, Budygin EA, Picetti R, Gainetdinov RR, Caron MG, Wightman RM. Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors. Neuroscience. 112: 39-49. PMID 12044470 DOI: 10.1016/S0306-4522(02)00067-2  1
2002 Richfield EK, Thiruchelvam MJ, Cory-Slechta DA, Wuertzer C, Gainetdinov RR, Caron MG, Di Monte DA, Federoff HJ. Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. Experimental Neurology. 175: 35-48. PMID 12009758 DOI: 10.1006/exnr.2002.7882  1
2002 Raevskii KS, Gainetdinov RR, Budygin EA, Mannisto P, Wightman M. Dopaminergic transmission in the rat striatum in vivo in conditions of pharmacological modulation. Neuroscience and Behavioral Physiology. 32: 183-8. PMID 11942697 DOI: 10.1023/A:1013931609942  1
2001 Gerber DJ, Sotnikova TD, Gainetdinov RR, Huang SY, Caron MG, Tonegawa S. Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 15312-7. PMID 11752469 DOI: 10.1073/pnas.261583798  1
2001 Gainetdinov RR, Mohn AR, Bohn LM, Caron MG. Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 98: 11047-54. PMID 11572967 DOI: 10.1073/pnas.191353298  1
2001 Gainetdinov RR, Mohn AR, Caron MG. Genetic animal models: Focus on schizophrenia Trends in Neurosciences. 24: 527-533. PMID 11506886 DOI: 10.1016/S0166-2236(00)01886-5  1
2001 Premont RT, Gainetdinov RR, Caron MG. Following the trace of elusive amines Proceedings of the National Academy of Sciences of the United States of America. 98: 9474-9475. PMID 11504935 DOI: 10.1073/pnas.181356198  1
2001 Sotnikova TD, Gainetdinov RR, Grekhova TV, Rayevsky KS. Effects of intrastriatal infusion of D2 and D3 dopamine receptor preferring antagonists on dopamine release in rat dorsal striatum (in vivo microdialysis study) Pharmacological Research. 43: 283-290. PMID 11401421 DOI: 10.1006/phrs.2000.0773  1
2001 Gainetdinov RR, Caron MG, Lombroso PJ. Genetics of childhood disorders: XXIV. ADHD, part 8: Hyperdopaminergic mice as an animal model of ADHD Journal of the American Academy of Child and Adolescent Psychiatry. 40: 380-382. PMID 11288782  1
2001 Budygin EA, Phillips PE, Robinson DL, Kennedy AP, Gainetdinov RR, Wightman RM. Effect of acute ethanol on striatal dopamine neurotransmission in ambulatory rats. The Journal of Pharmacology and Experimental Therapeutics. 297: 27-34. PMID 11259524  1
2001 Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1982-7. PMID 11172062 DOI: 10.1073/pnas.98.4.1982  1
2000 Bohn LM, Gainetdinov RR, Lin FT, Lefkowitz RJ, Caron MG. Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature. 408: 720-3. PMID 11130073 DOI: 10.1038/35047086  1
2000 Bohn LM, Xu F, Gainetdinov RR, Caron MG. Potentiated opioid analgesia in norepinephrine transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9040-5. PMID 11124980  1
2000 Gainetdinov RR, Premont RT, Caron MG, Lefkowitz RJ. Reply: receptor specificity of G-protein-coupled receptor kinases Trends in Pharmacological Sciences. 21: 366-7. PMID 11050311 DOI: 10.1016/S0165-6147(00)01538-8  1
2000 Walker JKL, Gainetdinov RR, Mangel AW, Caron MG, Shetzline MA. Mice lacking the dopamine transporter display altered regulation of distal colonic motility American Journal of Physiology - Gastrointestinal and Liver Physiology. 279: G311-G318. PMID 10915639  1
2000 Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, Wang YM, Caron MG. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nature Neuroscience. 3: 465-71. PMID 10769386 DOI: 10.1038/74839  1
2000 Logman MJ, Budygin EA, Gainetdinov RR, Wightman RM. Quantitation of in vivo measurements with carbon fiber microelectrodes. Journal of Neuroscience Methods. 95: 95-102. PMID 10752479 DOI: 10.1016/S0165-0270(99)00155-7  1
2000 Sarkis EH, Gainetdinov RR, Wetsel WC, Caron MG. 'Model' behavior [4] (multiple letters) Science. 287: 2160-2162. PMID 10744536  1
2000 Budygin EA, Kilpatrick MR, Gainetdinov RR, Wightman RM. Correlation between behavior and extracellular dopamine levels in rat striatum: comparison of microdialysis and fast-scan cyclic voltammetry. Neuroscience Letters. 281: 9-12. PMID 10686403 DOI: 10.1016/S0304-3940(00)00813-2  1
2000 Gainetdinov RR, Caron MG. An animal model of attention deficit hyperactivity disorder Molecular Medicine Today. 6: 43-44. PMID 10637574 DOI: 10.1016/S1357-4310(99)01616-0  1
2000 Caron MG, Mohn AR, Gainetdinov RR. Manifestation of dopamine and glutamate systems dysfunction in animal models of schizoid behavior Acta Neurologica Scandinavica, Supplement. 102: 14-15.  1
1999 Gainetdinov RR, Bohn LM, Walker JK, Laporte SA, Macrae AD, Caron MG, Lefkowitz RJ, Premont RT. Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice. Neuron. 24: 1029-36. PMID 10624964  1
1999 Bohn LM, Lefkowitz RJ, Gainetdinov RR, Peppel K, Caron MG, Lin FT. Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science (New York, N.Y.). 286: 2495-8. PMID 10617462 DOI: 10.1126/science.286.5449.2495  1
1999 Huotari M, Gainetdinov R, Männistö PT. Microdialysis studies on the action of tolcapone on pharmacologically- elevated extracellular dopamine levels in conscious rats Pharmacology and Toxicology. 85: 233-238. PMID 10608486  1
1999 Jones SR, Gainetdinov RR, Caron MG. Application of microdialysis and voltammetry to assess dopamine functions in genetically altered mice: correlation with locomotor activity. Psychopharmacology. 147: 30-2. PMID 10591864 DOI: 10.1007/s002130051137  1
1999 Budygin EA, Kilpatrick M, Ga?netdinov RR, Raevski? KS, Wightman RM. [The effect of the dopamine neuronal reuptake inhibitor GBR 12909 on the dopaminergic neurotransmission parameters in the rat striatum in vivo]. Eksperimental'Naia I Klinicheskaia Farmakologiia. 62: 3-6. PMID 10572741  1
1999 Wang YM, Xu F, Gainetdinov RR, Caron MG. Genetic approaches to studying norepinephrine function: Knockout of the mouse norepinephrine transporter gene Biological Psychiatry. 46: 1124-1130. PMID 10560019 DOI: 10.1016/S0006-3223(99)00245-0  1
1999 Gainetdinov RR, Caron MG. Delineating muscarinic receptor functions Proceedings of the National Academy of Sciences of the United States of America. 96: 12222-12223. PMID 10535900 DOI: 10.1073/pnas.96.22.12222  1
1999 Miller GW, Gainetdinov RR, Levey AI, Caron MG. Dopamine transporters and neuronal injury. Trends in Pharmacological Sciences. 20: 424-9. PMID 10498956 DOI: 10.1016/S0165-6147(99)01379-6  1
1999 Mohn AR, Gainetdinov RR, Caron MG, Koller BH. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia Cell. 98: 427-436. PMID 10481908 DOI: 10.1016/S0092-8674(00)81972-8  1
1999 Gainetdinov RR, Jones SR, Caron MG. Functional hyperdopaminergia in dopamine transporter knock-out mice. Biological Psychiatry. 46: 303-11. PMID 10435196 DOI: 10.1016/S0006-3223(99)00122-5  1
1999 Jones SR, Gainetdinov RR, Hu XT, Cooper DC, Wightman RM, White FJ, Caron MG. Loss of autoreceptor functions in mice lacking the dopamine transporter. Nature Neuroscience. 2: 649-55. PMID 10404198 DOI: 10.1038/10204  1
1999 Gainetdinov RR, Caron MG. Genetic models in pharmacology: Present status and future Pharmacological Research. 39: 403-404. PMID 10373248 DOI: 10.1006/phrs.1999.0498  1
1999 Budygin EA, Gainetdinov RR, Kilpatrick MR, Rayevsky KS, Männistö PT, Wightman RM. Effect of tolcapone, a catechol-O-methyltransferase inhibitor, on striatal dopaminergic transmission during blockade of dopamine uptake. European Journal of Pharmacology. 370: 125-31. PMID 10323260 DOI: 10.1016/S0014-2999(99)00084-9  1
1999 Fumagalli F, Gainetdinov RR, Wang YM, Valenzano KJ, Miller GW, Caron MG. Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2424-31. PMID 10087057  1
1999 Melnikova V, Orosco M, Calas A, Sapronova A, Gainetdinov R, Delhaye-Bouchaud N, Nicolaidis S, Rayevsky K, Ugrumov M. Dopamine turnover in the mediobasal hypothalamus in rat fetuses. Neuroscience. 89: 235-41. PMID 10051232 DOI: 10.1016/S0306-4522(98)00278-4  1
1999 Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (New York, N.Y.). 283: 397-401. PMID 9888856 DOI: 10.1126/science.283.5400.397  1
1999 Budygin EA, Kilpatrick M, Gainetdinov RR, Rayevsky KS, Wightman RM. The effect of the dopamine re-uptake inhibitor GBR 12909 on dopaminergic neurotransmission in rat striatum in vivo Eksperimental'Naya I Klinicheskaya Farmakologiya. 62: 5-6.  1
1998 Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, Miller GW, Caron MG. Cocaine self-administration in dopamine-transporter knockout mice. Nature Neuroscience. 1: 132-7. PMID 10195128 DOI: 10.1038/381  1
1998 Gainetdinov RR, Jones SR, Fumagalli F, Wightman RM, Caron MG. Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. Brain Research. Brain Research Reviews. 26: 148-53. PMID 9651511 DOI: 10.1016/S0165-0173(97)00063-5  1
1998 Fumagalli F, Gainetdinov RR, Valenzano KJ, Caron MG. Role of dopamine transporter in methamphetamine-induced neurotoxicity: Evidence from mice lacking the transporter Journal of Neuroscience. 18: 4861-4869. PMID 9634552  1
1998 Gainetdinov RR, Fumagalli F, Wang YM, Jones SR, Levey AI, Miller GW, Caron MG. Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. Journal of Neurochemistry. 70: 1973-8. PMID 9572281  1
1998 Budygin EA, Ga?netdinov RR, Raevski? KS, Mannisto PT. [Effect of subchronic administration of tolcapone on release of striatum dopamine and its metabolites induced by L-DOPA and carbidopa]. Biulleten' Eksperimental'Noĭ Biologii I Meditsiny. 125: 168-71. PMID 9559129  1
1998 Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 4029-34. PMID 9520487 DOI: 10.1073/pnas.95.7.4029  1
1998 Jones SR, Gainetdinov RR, Wightman RM, Caron MG. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1979-86. PMID 9482784  1
1998 Budygin EA, Gainetdinov RR, Raevskii KS, Mannisto PT. Effect of subchronic administration of tolcapone on L-DOPA- and carbidopa-induced release of striatal dopamine and its metabolites Bulletin of Experimental Biology and Medicine. 125: 145-147.  1
1997 Gainetdinov RR, Sotnikova TD, Grekhova TV, Rayevsky KS. Effects of a psychostimulant drug sydnocarb on rat brain dopaminergic transmission in vivo European Journal of Pharmacology. 340: 53-58. PMID 9527506 DOI: 10.1016/S0014-2999(97)01407-6  1
1997 Budygin EA, Ga?netdinov RR, Raevski? KS, Li IH, Mannisto PT. [Microdialysis study of tolcapone effect during blockage of neuronal dopamine reuptake caused by GBR-12909]. Eksperimental'Naia I Klinicheskaia Farmakologiia. 60: 8-10. PMID 9483396  1
1997 Wang YM, Gainetdinov RR, Fumagalli F, Xu F, Jones SR, Bock CB, Miller GW, Wightman RM, Caron MG. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron. 19: 1285-96. PMID 9427251 DOI: 10.1016/S0896-6273(00)80419-5  1
1997 Gainetdinov RR, Fumagalli F, Jones SR, Caron MG. Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. Journal of Neurochemistry. 69: 1322-5. PMID 9282960  1
1997 Bossé R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC, Missale C, Caron MG. Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 19: 127-38. PMID 9247269 DOI: 10.1016/S0896-6273(00)80353-0  1
1997 Budygin EA, Ga?netdinov RR, Titov DA, Kovalev GI. [Effect of aspartic acid derivatives, N-acetyl-aspartate and its phosphonic analog PIR-87-6-0, on dopamine release from the rat striatum during perfusion in vitro]. Biulleten' Eksperimental'Noĭ Biologii I Meditsiny. 123: 57-60. PMID 9213460  1
1997 Budygin EA, Gainetdinov RR, Raevsky KS, Li IH, Mannisto PT. Microdialysis of the effect of tolcapone in GBR-12909-induced blockade of dopamine uptake Eksperimental'Naya I Klinicheskaya Farmakologiya. 60: 10.  1
1997 Rayevsky KS, Gainetdinov RR, Sotnikova TD. Functional heterogeneity of brain dopamine recetors and effects of old and new antipsychotics Faseb Journal. 11: A212.  1
1997 Budygin EA, Gainetdinov RR, Titov DA, Kovalev GI. Effect of the aspartic acid derivatives N-acetyl-aspartate and its phosphonic analog PIR-87-6-0 on the release of dopamine from rat striatum during in vitro perfusion Bulletin of Experimental Biology and Medicine. 123: 49-51.  1
1996 Raevskii KS, Sotnikova TD, Gainetdinov RR. The brain dopaminergic systems: receptor heterogeneity, functional role and pharmacological regulation | Dofaminergicheskie sistemy mozga: retseptornaia geterogennost', funktsional'naia rol', farmakologicheskaia reguliatsiia Uspekhi Fiziologicheskikh Nauk. 27: 3-29. PMID 9019922  1
1996 Budygin EA, Ga?netdinov RR, Titov DA, Kovalev GI. [The effect of a low dose of piracetam on the activity of the dopaminergic system in the rat striatum]. Eksperimental'Naia I Klinicheskaia Farmakologiia. 59: 6-8. PMID 8974570  1
1996 Gainetdinov RR, Sotnikova TD, Grekhova TV, Rayevsky KS. Simultaneous monitoring of dopamine, its metabolites and trans-isomer of atypical neuroleptic drug carbidine concentrations in striatal dialysates of conscious rats Progress in Neuro-Psychopharmacology and Biological Psychiatry. 20: 291-305. PMID 8861194 DOI: 10.1016/0278-5846(95)00311-8  1
1996 Gainetdinov RR, Sotnikova TD, Grekhova TV, Rayevsky KS. In vivo evidence for preferential role of dopamine D3 receptor in the presynaptic regulation of dopamine release but not synthesis European Journal of Pharmacology. 308: 261-269. PMID 8858296 DOI: 10.1016/0014-2999(96)00300-7  1
1996 Gainetdinov RR, Raevskii KS. Substances that increase the extracellular level of dopamine in the striatum prevent development of haloperidol catalepsy in rats | Veshchestva, povyshaiushchie ékstrakletochnoe soderzhanie dofamina v striatum, prepiatstvuiut razvitiiu galoperiodolvoi katalepsii u krys Biulleten' Eksperimental'Noi Biologii I Meditsiny. 121: 438-440. PMID 8829461  1
1996 Sotnikova TD, Gainetdinov RR, Grekhova TV, Raevskii KS. Dopamine autoreceptors subtype D3 predominantly regulate the liberation of dopamine in rat brain basal ganglia | Dofaminovye autoretseptory D3 podtipa preimushchestvenno reguliruiut vysvobozhdenie dofamina v bazal'nykh gangliiakh mozga krys Biulleten' Eksperimental'Noi Biologii I Meditsiny. 121: 430-434. PMID 8829459  1
1996 Budygin EA, Gainetdinov RR, Titov DA, Kovalev GI. The low-dose effect of pyracetam on the activity of the dopaminergic system of the striatum in the brain of rats Eksperimental'Naya I Klinicheskaya Farmakologiya. 59: 8.  1
1996 Gainetdinov RR, Raevskii KS. Substances increasing the extracellular content of dopamine in the striatum prevent the development of haloperidol catalepsy in rats Bulletin of Experimental Biology and Medicine. 121: 399-401.  1
1996 Sotnikova TD, Gainetdinov RR, Grekhova TV, Raevskii KS. Dopamine autoreceptors of subtype D3 regulate mainly dopamine release in the basal ganglia of rat brain Bulletin of Experimental Biology and Medicine. 121: 392-396.  1
1995 Rayevsky KS, Gainetdinov RR, Grekhova TV, Sotnikova TD. Regulation of dopamine release and metabolism in rat striatum in vivo: Effects of dopamine receptor antagonists Progress in Neuropsychopharmacology and Biological Psychiatry. 19: 1285-1303. PMID 8868210 DOI: 10.1016/0278-5846(95)00267-7  1
1995 Salimov RM, Poletaeva II, Kovalev GI, Salimova NB, Gainetdinov RR. Interstrain differences in extrapolation capacity and exploration of a cruciform maze correlate with various indices of monoamine metabolism in the brain | Mezhlineinye razlichia v sposobnosti k ékstrapoliatsii i v osvoenii krestoobraznogo labirinta korreliruiut s raznymi pokazateliami obmena monoaminov mozga Zhurnal Vysshei Nervnoi Deiatelnosti Imeni I P Pavlova. 45: 914-924. PMID 8560938  1
1995 Gainetdinov RR, Sotnikova TD, Grekhova TV, Rayevsky KS. Estimation of the interstitial free concentration of the putative dopamine D3 receptor selective agonist 7-OH-DPAT in the dorsal striatum of freely moving rats Neuroscience Letters. 193: 65-67. PMID 7566669 DOI: 10.1016/0304-3940(95)11653-E  1
1995 Grekhova TV, Gainetdinov RR, Sotnikova TD, Krasnykh LM, Kudrin VS, Sergeeva SA, Morozov IS. Effect of bromantane, a new immunostimulating agent with psychostimulating activity, on the release and metabolism of dopamine in the striatum of freely moving rats. A microdialysis study Bulletin of Experimental Biology and Medicine. 119: 294-296. DOI: 10.1007/BF02445840  1
1994 Gainetdinov RR, Grekhova TV, Sotnikova TD, Rayevsky KS. Dopamine D2 and D3 receptor preferring antagonists differentially affect striatal dopamine release and metabolism in conscious rats European Journal of Pharmacology. 261: 327-331. PMID 7813556 DOI: 10.1016/0014-2999(94)90125-2  1
1993 Kovalev GI, Budygin EA, Gainetdinov RR, Kudrin VS, Trofimov SS, Ostrovskaya RU. Use of sodium hydroxybutyrate and nooglutyl to correct dopamine release in the striatum of prenatally alcoholized rat pups Bulletin of Experimental Biology and Medicine. 116: 832-834. DOI: 10.1007/BF00786165  1
Show low-probability matches.