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Dennis Hyong-Kyun Kim - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Immunology
Website:
https://biology.mit.edu/people/dennis_kim
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fletcher M, Tillman EJ, Butty VL, Levine SS, Kim DH. Global transcriptional regulation of innate immunity by ATF-7 in C. elegans. Plos Genetics. 15: e1007830. PMID 30789901 DOI: 10.1371/Journal.Pgen.1007830  0.411
2018 Tillman EJ, Richardson CE, Cattie DJ, Reddy KC, Lehrbach NJ, Droste R, Ruvkun G, Kim DH. Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of . Genetics. PMID 30287474 DOI: 10.1534/Genetics.118.301450  0.577
2017 Kulalert W, Sadeeshkumar H, Zhang YK, Schroeder FC, Kim DH. Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation in Caenorhabditis elegans. Genetics. PMID 28292919 DOI: 10.1534/Genetics.117.200568  0.331
2017 Fletcher M, Kim DH. Age-Dependent Neuroendocrine Signaling from Sensory Neurons Modulates the Effect of Dietary Restriction on Longevity of Caenorhabditis elegans. Plos Genetics. 13: e1006544. PMID 28107363 DOI: 10.1371/Journal.Pgen.1006544  0.334
2016 Cattie DJ, Richardson CE, Reddy KC, Ness-Cohn EM, Droste R, Thompson MK, Gilbert WV, Kim DH. Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans. Plos Genetics. 12: e1006326. PMID 27690135 DOI: 10.1371/Journal.Pgen.1006326  0.31
2015 Kim DH, Ewbank JJ. Signaling in the innate immune response. Wormbook : the Online Review of C. Elegans Biology. 1-51. PMID 26694508 DOI: 10.1895/Wormbook.1.83.2  0.389
2015 Kim DH. Signal Transduction: A Different Kind of Toll Is in the BAG. Current Biology : Cb. 25: R767-9. PMID 26325140 DOI: 10.1016/J.Cub.2015.06.057  0.318
2014 Meisel JD, Panda O, Mahanti P, Schroeder FC, Kim DH. Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegans. Cell. 159: 267-80. PMID 25303524 DOI: 10.1016/J.Cell.2014.09.011  0.381
2014 Meisel JD, Kim DH. Behavioral avoidance of pathogenic bacteria by Caenorhabditis elegans Trends in Immunology. 35: 465-470. PMID 25240986 DOI: 10.1016/J.It.2014.08.008  0.362
2013 Kulalert W, Kim DH. The unfolded protein response in a pair of sensory neurons promotes entry of C. elegans into dauer diapause. Current Biology : Cb. 23: 2540-5. PMID 24316205 DOI: 10.1016/J.Cub.2013.10.058  0.348
2013 Kim DH. Bacteria and the aging and longevity of caenorhabditis elegans Annual Review of Genetics. 47: 233-246. PMID 24274752 DOI: 10.1146/Annurev-Genet-111212-133352  0.394
2011 Richardson CE, Kinkel S, Kim DH. Physiological IRE-1-XBP-1 and PEK-1 signaling in Caenorhabditis elegans larval development and immunity. Plos Genetics. 7: e1002391. PMID 22125500 DOI: 10.1371/Journal.Pgen.1002391  0.354
2011 Chang HC, Paek J, Kim DH. Natural polymorphisms in C. elegans HECW-1 E3 ligase affect pathogen avoidance behaviour Nature. 480: 525-529. PMID 22089131 DOI: 10.1038/Nature10643  0.376
2011 Reddy KC, Hunter RC, Bhatla N, Newman DK, Kim DH. Caenorhabditis elegans NPR-1-mediated behaviors are suppressed in the presence of mucoid bacteria. Proceedings of the National Academy of Sciences of the United States of America. 108: 12887-92. PMID 21768378 DOI: 10.1073/Pnas.1108265108  0.338
2011 Youngman MJ, Rogers ZN, Kim DH. A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. Plos Genetics. 7: e1002082. PMID 21625567 DOI: 10.1371/Journal.Pgen.1002082  0.394
2010 Shivers RP, Pagano DJ, Kooistra T, Richardson CE, Reddy KC, Whitney JK, Kamanzi O, Matsumoto K, Hisamoto N, Kim DH. Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans. Plos Genetics. 6: e1000892. PMID 20369020 DOI: 10.1371/Journal.Pgen.1000892  0.409
2010 Richardson CE, Kooistra T, Kim DH. An essential role for XBP-1 in host protection against immune activation in C. elegans. Nature. 463: 1092-5. PMID 20182512 DOI: 10.1038/Nature08762  0.446
2009 Shivers RP, Kooistra T, Chu SW, Pagano DJ, Kim DH. Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans. Cell Host & Microbe. 6: 321-30. PMID 19837372 DOI: 10.1016/J.Chom.2009.09.001  0.432
2009 Powell JR, Kim DH, Ausubel FM. The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 106: 2782-7. PMID 19196974 DOI: 10.1073/Pnas.0813048106  0.676
2009 Reddy KC, Andersen EC, Kruglyak L, Kim DH. A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Science (New York, N.Y.). 323: 382-4. PMID 19150845 DOI: 10.1126/Science.1166527  0.4
2008 Kim D. Studying host-pathogen interactions and innate immunity in Caenorhabditis elegans Dmm Disease Models and Mechanisms. 1: 205-208. PMID 19093025 DOI: 10.1242/Dmm.000265  0.397
2008 Shivers RP, Youngman MJ, Kim DH. Transcriptional responses to pathogens in Caenorhabditis elegans. Current Opinion in Microbiology. 11: 251-6. PMID 18567532 DOI: 10.1016/J.Mib.2008.05.014  0.406
2006 Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, Kim DH. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. Plos Genetics. 2: e183. PMID 17096597 DOI: 10.1371/Journal.Pgen.0020183  0.6
2005 Kim DH, Ausubel FM. Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Current Opinion in Immunology. 17: 4-10. PMID 15653303 DOI: 10.1016/J.Coi.2004.11.007  0.589
2004 Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM. Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 101: 10990-4. PMID 15256594 DOI: 10.1073/Pnas.0403546101  0.574
2004 Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proceedings of the National Academy of Sciences of the United States of America. 101: 6593-8. PMID 15123841 DOI: 10.1073/Pnas.0308625101  0.583
2004 Mizuno T, Hisamoto N, Terada T, Kondo T, Adachi M, Nishida E, Kim DH, Ausubel FM, Matsumoto K. The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. The Embo Journal. 23: 2226-34. PMID 15116070 DOI: 10.1038/Sj.Emboj.7600226  0.56
2003 Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science (New York, N.Y.). 300: 1921. PMID 12817143 DOI: 10.1126/Science.1080147  0.722
2002 Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM. A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science (New York, N.Y.). 297: 623-6. PMID 12142542 DOI: 10.1126/Science.1073759  0.709
1998 Skarzynski T, Kim DH, Lees WJ, Walsh CT, Duncan K. Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA. Biochemistry. 37: 2572-7. PMID 9485407 DOI: 10.1021/Bi9722608  0.667
1996 Walsh CT, Benson TE, Kim DH, Lees WJ. The versatility of phosphoenolpyruvate and its vinyl ether products in biosynthesis. Chemistry & Biology. 3: 83-91. PMID 8807832 DOI: 10.1016/S1074-5521(96)90282-3  0.635
1996 Kim DH, Lees WJ, Kempsell KE, Lane WS, Duncan K, Walsh CT. Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. Biochemistry. 35: 4923-8. PMID 8664284 DOI: 10.1021/Bi952937W  0.655
1996 Kim DH, Tucker-Kellogg GW, Lees WJ, Walsh CT. Analysis of fluoromethyl group chirality establishes a common stereochemical course for the enolpyruvyl transfers catalyzed by EPSP synthase and UDP-GlcNAc enolpyruvyl transferase. Biochemistry. 35: 5435-40. PMID 8611533 DOI: 10.1021/Bi952978S  0.657
1995 Kim DH, Lees WJ, Walsh CT. Stereochemical analysis of the tetrahedral adduct formed at the active site of UDP-GlcNAc enolpyruvyl transferase from the pseudosubstrates, (E)- and (Z)-3-fluorophosphoenolpyruvate, in D2O Journal of the American Chemical Society. 117: 6380-6381. DOI: 10.1021/Ja00128A037  0.638
1995 Kim DH, Lees WJ, Haley TM, Walsh CT. Kinetic characterization of the inactivation of UDP-GlcNAc enolpyruvyl transferase by (Z)-3-fluorophosphoenolpyruvate: Evidence for two oxocarbenium ion intermediates in enolpyruvyl transfer catalysis Journal of the American Chemical Society. 117: 1494-1502. DOI: 10.1021/Ja00110A005  0.63
1994 Kim DH, Lees WJ, Walsh CT. Formation of two enzyme-bound reaction intermediate analogs during inactivation of UDP-GlcNAc enolpyruvyl transferase by (E)- or (Z)-3-fluorophosphoenolpyruvate Journal of the American Chemical Society. 116: 6478-6479. DOI: 10.1021/Ja00093A076  0.65
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