Year |
Citation |
Score |
2024 |
Ding X, Chen X, Sullivan EE, Shay TF, Gradinaru V. Fast, accurate ranking of engineered proteins by target binding propensity using structure modeling. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 38582966 DOI: 10.1016/j.ymthe.2024.04.003 |
0.701 |
|
2023 |
Coughlin GM, Borsos M, Appling N, Barcelona BH, Mayfield AMH, Mackey ED, Eser RA, Chen X, Kumar SR, Gradinaru V. Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo. Biorxiv : the Preprint Server For Biology. PMID 38187707 DOI: 10.1101/2023.12.23.573214 |
0.579 |
|
2023 |
Chuapoco MR, Flytzanis NC, Goeden N, Christopher Octeau J, Roxas KM, Chan KY, Scherrer J, Winchester J, Blackburn RJ, Campos LJ, Man KNM, Sun J, Chen X, Lefevre A, Singh VP, et al. Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain. Nature Nanotechnology. PMID 37430038 DOI: 10.1038/s41565-023-01419-x |
0.653 |
|
2023 |
Campos LJ, Arokiaraj CM, Chuapoco MR, Chen X, Goeden N, Gradinaru V, Fox AS. Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system. Current Research in Neurobiology. 4: 100086. PMID 37397806 DOI: 10.1016/j.crneur.2023.100086 |
0.607 |
|
2023 |
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Nature Communications. 14: 3345. PMID 37291094 DOI: 10.1038/s41467-023-38582-7 |
0.769 |
|
2023 |
Shay TF, Sullivan EE, Ding X, Chen X, Ravindra Kumar S, Goertsen D, Brown D, Crosby A, Vielmetter J, Borsos M, Wolfe DA, Lam AW, Gradinaru V. Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances. 9: eadg6618. PMID 37075114 DOI: 10.1126/sciadv.adg6618 |
0.758 |
|
2023 |
Chuapoco M, Flytzanis N, Goeden N, Octeau J, Roxas K, Chan K, Scherrer J, Winchester J, Blackburn R, Campos L, Man KN, Sun J, Chen X, Lefevre A, Singh V, et al. Intravenous functional gene transfer throughout the brain of non-human primates using AAV. Research Square. PMID 36789432 DOI: 10.21203/rs.3.rs-1370972/v1 |
0.652 |
|
2023 |
Chen X, Wolfe DA, Sivadasan Bindu D, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan E, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner V, Campos LJ, Mich J, Monet D, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Biorxiv : the Preprint Server For Biology. PMID 36711773 DOI: 10.1101/2023.01.12.523844 |
0.769 |
|
2023 |
Jang MJ, Coughlin GM, Jackson CR, Chen X, Chuapoco MR, Vendemiatti JL, Wang AZ, Gradinaru V. Spatial transcriptomics for profiling the tropism of viral vectors in tissues. Nature Biotechnology. PMID 36702899 DOI: 10.1038/s41587-022-01648-w |
0.619 |
|
2022 |
Chen X, Ravindra Kumar S, Adams CD, Yang D, Wang T, Wolfe DA, Arokiaraj CM, Ngo V, Campos LJ, Griffiths JA, Ichiki T, Mazmanian SK, Osborne PB, Keast JR, Miller CT, et al. Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems. Neuron. PMID 35643078 DOI: 10.1016/j.neuron.2022.05.003 |
0.6 |
|
2022 |
Challis RC, Ravindra Kumar S, Chen X, Goertsen D, Coughlin GM, Hori AM, Chuapoco MR, Otis TS, Miles TF, Gradinaru V. Adeno-Associated Virus Toolkit to Target Diverse Brain Cells. Annual Review of Neuroscience. PMID 35440143 DOI: 10.1146/annurev-neuro-111020-100834 |
0.762 |
|
2021 |
Kahan A, Greenbaum A, Jang MJ, Robinson JE, Cho JR, Chen X, Kassraian P, Wagenaar DA, Gradinaru V. Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses. Cell Reports. 36: 109744. PMID 34592157 DOI: 10.1016/j.celrep.2021.109744 |
0.554 |
|
2021 |
Cho JR, Chen X, Kahan A, Robinson JE, Wagenaar DA, Gradinaru V. Dorsal raphe dopamine neurons signal motivational salience dependent on internal state, expectation, and behavioral context. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33563725 DOI: 10.1523/JNEUROSCI.2690-20.2021 |
0.553 |
|
2020 |
Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, et al. Negative feedback control of neuronal activity by microglia. Nature. PMID 32999463 DOI: 10.1038/s41586-020-2777-8 |
0.707 |
|
2020 |
Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V. Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types. Nature Methods. PMID 32313222 DOI: 10.1038/S41592-020-0799-7 |
0.755 |
|
2019 |
Siciliano CA, Noamany H, Chang CJ, Brown AR, Chen X, Leible D, Lee JJ, Wang J, Vernon AN, Vander Weele CM, Kimchi EY, Heiman M, Tye KM. A cortical-brainstem circuit predicts and governs compulsive alcohol drinking. Science (New York, N.Y.). 366: 1008-1012. PMID 31754002 DOI: 10.1126/Science.Aay1186 |
0.588 |
|
2019 |
Siciliano C, Noamany H, Chen X, Leible D, Brown A, Chang C, Lee J, Wang J, Vernon A, Weele CV, Kimchi E, Heiman M, Tye K. S207. Cortical-Brainstem Projections Gate Compulsive Alcohol Drinking Biological Psychiatry. 85: S377. DOI: 10.1016/J.Biopsych.2019.03.958 |
0.564 |
|
2017 |
Huang J, Feng Y, Chen X, Li W, Xue L. Myc inhibits JNK-mediated cell death in vivo. Apoptosis : An International Journal On Programmed Cell Death. PMID 28150056 DOI: 10.1007/S10495-016-1340-4 |
0.487 |
|
2016 |
Wang X, Zhao Y, Hu Y, Ren P, Sun Y, Guo X, Huang X, Zhu Y, Chen X, Feng Y, Xue L. Establishment of a AD model. Journal of Biological Methods. 3: e43. PMID 31453210 DOI: 10.14440/jbm.2016.61 |
0.425 |
|
2016 |
Zhuang L, Sun Y, Hu M, Wu C, La X, Chen X, Feng Y, Wang X, Hu Y, Xue L. Or47b plays a role in Drosophila males' preference for younger mates. Open Biology. 6. PMID 27278650 DOI: 10.1098/Rsob.160086 |
0.465 |
|
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