| Year |
Citation |
Score |
| 2024 |
Hajós M, Boasso A, Hempel E, Shpokayte M, Konisky A, Seshagiri CV, Fomenko V, Kwan K, Nicodemus-Johnson J, Hendrix S, Vaughan B, Kern R, Megerian JT, Malchano Z. Safety, tolerability, and efficacy estimate of evoked gamma oscillation in mild to moderate Alzheimer's disease. Frontiers in Neurology. 15: 1343588. PMID 38515445 DOI: 10.3389/fneur.2024.1343588 |
0.338 |
|
| 2023 |
Acker BA, Badescu VO, Berkenpas MB, Groppi VE, Hajós M, Higdon NR, Hurst RS, Jon Jacobsen E, Margolis BJ, McWhorter WW, Myers JK, Piotrowski DW, Rogers BN, Sarapa D, Vetman TN, et al. Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor: SAR Investigation Around PNU-120596. Bioorganic & Medicinal Chemistry Letters. 129433. PMID 37557923 DOI: 10.1016/j.bmcl.2023.129433 |
0.317 |
|
| 2021 |
Cimenser A, Hempel E, Travers T, Strozewski N, Martin K, Malchano Z, Hajós M. Sensory-Evoked 40-Hz Gamma Oscillation Improves Sleep and Daily Living Activities in Alzheimer's Disease Patients. Frontiers in Systems Neuroscience. 15: 746859. PMID 34630050 DOI: 10.3389/fnsys.2021.746859 |
0.308 |
|
| 2021 |
Stoiljkovic M, Gutierrez KO, Kelley C, Horvath TL, Hajós M. TREM2 Deficiency Disrupts Network Oscillations Leading to Epileptic Activity and Aggravates Amyloid-β-Related Hippocampal Pathophysiology in Mice. Journal of Alzheimer's Disease : Jad. PMID 34120899 DOI: 10.3233/JAD-210041 |
0.752 |
|
| 2021 |
Jin N, Babiloni C, Drinkenburg WH, Hajós M, Nygaard HB, Tanila H. Recommendations for Preclinical Testing of Treatments Against Alzheimer's Disease-Related Epileptiform Spikes in Transgenic Rodent Models. Journal of Alzheimer's Disease : Jad. PMID 34092642 DOI: 10.3233/JAD-210209 |
0.308 |
|
| 2020 |
Kozak R, Kiss T, Dlugolenski K, Johnson DE, Gorczyca RR, Kuszpit K, Harvey BD, Stolyar P, Sukoff Rizzo SJ, Hoffmann WE, Volfson D, Hajós M, Davoren JE, Abbott AL, Williams GV, et al. Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation. Frontiers in Pharmacology. 11: 1005. PMID 32733245 DOI: 10.3389/Fphar.2020.01005 |
0.38 |
|
| 2020 |
Tan Y, Hang F, Liu ZW, Stoiljkovic M, Wu M, Tu Y, Han W, Lee AM, Kelley C, Hajos M, Lu L, de Lecea L, de Araujo I, Picciotto M, Horvath TL, et al. Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. The Journal of Clinical Investigation. PMID 32516139 DOI: 10.1172/Jci130889 |
0.727 |
|
| 2019 |
Babiloni C, Blinowska K, Bonanni L, Cichocki A, De Haan W, Del Percio C, Dubois B, Escudero J, Fernández A, Frisoni G, Guntekin B, Hajos M, Hampel H, Ifeachor E, Kilborn K, et al. What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons. Neurobiology of Aging. 85: 58-73. PMID 31739167 DOI: 10.1016/J.Neurobiolaging.2019.09.008 |
0.427 |
|
| 2019 |
Nagy D, Martens LH, Leventhal L, Chen A, Kelley C, Stoiljkovic M, Hajós M. Age-dependent emergence of neurophysiological and behavioral abnormalities in progranulin-deficient mice. Alzheimer's Research & Therapy. 11: 88. PMID 31639062 DOI: 10.1186/S13195-019-0540-X |
0.734 |
|
| 2019 |
Harvey BD, Komorowski R, Palumbo R, Spencer KM, Budson A, Hajos M. P4-074: EARLY DETECTION OF ABNORMAL SENSORY-EVOKED EEG RESPONSES IN MICE OVER-EXPRESSING AMYLOID BETA Alzheimer's & Dementia. 15: P1302-P1303. DOI: 10.1016/J.Jalz.2019.06.3734 |
0.303 |
|
| 2019 |
Choi J, Czerkowicz J, Craft M, Stoiljkovic M, Leach P, Bieber V, Halftermeyer A, Marsh G, Hamann S, Plowey E, Reynolds TL, Arnold M, Hajos M, Hering H. P4-058: A Novel Transgenic Rat Model That Presents Pathophysiological Levels Of Human Tau In Csf, Axonopathy, Hippocampal Network Disruption, And Cognitive Deficits Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3718 |
0.375 |
|
| 2018 |
Stoiljkovic M, Kelley C, Horvath TL, Hajós M. Neurophysiological signals as predictive translational biomarkers for Alzheimer's disease treatment: effects of donepezil on neuronal network oscillations in TgF344-AD rats. Alzheimer's Research & Therapy. 10: 105. PMID 30301466 DOI: 10.1186/S13195-018-0433-4 |
0.775 |
|
| 2018 |
Stoiljkovic M, Kelley C, Stutz B, Horvath TL, Hajós M. Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology. Cerebral Cortex (New York, N.Y. : 1991). PMID 29920597 DOI: 10.1093/Cercor/Bhy140 |
0.772 |
|
| 2018 |
Skosnik PD, Hajós M, Cortes-Briones JA, Edwards CR, Pittman BP, Hoffmann WE, Sewell AR, D'Souza DC, Ranganathan M. Cannabinoid receptor-mediated disruption of sensory gating and neural oscillations: A translational study in rats and humans. Neuropharmacology. PMID 29604295 DOI: 10.1016/J.Neuropharm.2018.03.036 |
0.351 |
|
| 2018 |
Helal CJ, Arnold EP, Boyden TL, Chang C, Chappie TA, Fisher E, Hajós M, Harms JF, Hoffmann WE, Humphrey JM, Pandit J, Kang Z, Kleiman RJ, Kormos BL, Lee CW, et al. Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate. Journal of Medicinal Chemistry. PMID 29293004 DOI: 10.1021/Acs.Jmedchem.7B01466 |
0.302 |
|
| 2017 |
Helal CJ, Arnold EP, Boyden TL, Chang C, Chappie TA, Fennell KF, Forman MD, Hajós M, Harms JF, Hoffmann WE, Humphrey JM, Kang Z, Kleiman RJ, Kormos BL, Lee CW, et al. Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor. Journal of Medicinal Chemistry. PMID 28574706 DOI: 10.1021/Acs.Jmedchem.7B00397 |
0.304 |
|
| 2017 |
Stoiljkovic M, Kelley C, Hajos M. Abnormal cortical and hippocampal neuronal activity in TgF344-AD rats modeling Alzheimer’s disease pathology Journal of the Neurological Sciences. 381: 135-136. DOI: 10.1016/J.Jns.2017.08.405 |
0.759 |
|
| 2017 |
Skosnik P, Hajos M, Cortes-Briones J, Pittman B, Sewell A, D’Souza D, Ranganathan M. 63. Cannabinoid-Mediated Disruption of Sensory Gating and Neural Network Oscillations: A Translational Study in Humans and Rats Biological Psychiatry. 81: S26-S27. DOI: 10.1016/J.Biopsych.2017.02.074 |
0.317 |
|
| 2016 |
Stoiljkovic M, Kelley C, Nagy D, Hurst R, Hajós M. Activation of α7 nicotinic acetylcholine receptors facilitates long-term potentiation at the hippocampal-prefrontal cortex synapses in vivo. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27866776 DOI: 10.1016/J.Euroneuro.2016.11.003 |
0.753 |
|
| 2016 |
Stoiljkovic M, Kelley C, Hajós GP, Nagy D, Koenig G, Leventhal L, Hajós M. Hippocampal network dynamics in response to α7 nACh receptors activation in amyloid-β overproducing transgenic mice. Neurobiology of Aging. 45: 161-168. PMID 27459936 DOI: 10.1016/J.Neurobiolaging.2016.05.021 |
0.769 |
|
| 2016 |
Stoiljkovic M, Kelley C, Nagy D, Leventhal L, Hajós M. Selective activation of α7 nicotinic acetylcholine receptors augments hippocampal oscillations. Neuropharmacology. PMID 27422408 DOI: 10.1016/J.Neuropharm.2016.07.010 |
0.763 |
|
| 2016 |
Hermes G, Nagy D, Waterson M, Zsarnovszky A, Varela L, Hajos M, Horvath TL. Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation. Molecular Metabolism. 5: 415-21. PMID 27257601 DOI: 10.1016/J.Molmet.2016.04.002 |
0.362 |
|
| 2016 |
Engin E, Smith KS, Gao Y, Nagy D, Foster RA, Tsvetkov E, Keist R, Crestani F, Fritschy JM, Bolshakov VY, Hajos M, Heldt SA, Rudolph U. Modulation of anxiety and fear via distinct intrahippocampal circuits. Elife. 5. PMID 26971710 DOI: 10.7554/Elife.14120 |
0.399 |
|
| 2015 |
Skosnik PD, Cortes-Briones JA, Hajós M. It's All in the Rhythm: The Role of Cannabinoids in Neural Oscillations and Psychosis. Biological Psychiatry. PMID 26850792 DOI: 10.1016/J.Biopsych.2015.12.011 |
0.366 |
|
| 2015 |
Scott L, Kiss T, Kawabe TT, Hajós M. Neuronal network activity in the hippocampus of tau transgenic (Tg4510) mice. Neurobiology of Aging. PMID 26610388 DOI: 10.1016/J.Neurobiolaging.2015.10.002 |
0.433 |
|
| 2015 |
Linderholm KR, Alm MT, Larsson MK, Olsson SK, Goiny M, Hajos M, Erhardt S, Engberg G. Inhibition of kynurenine aminotransferase II reduces activity of midbrain dopamine neurons. Neuropharmacology. PMID 26514401 DOI: 10.1016/J.Neuropharm.2015.10.028 |
0.376 |
|
| 2015 |
Nagy D, Stoiljkovic M, Menniti FS, Hajós M. Differential Effects of an NR2B NAM and Ketamine on Synaptic Potentiation and Gamma Synchrony: Relevance to Rapid-Onset Antidepressant Efficacy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26404843 DOI: 10.1038/Npp.2015.298 |
0.338 |
|
| 2015 |
Stoiljkovic M, Kelley C, Nagy D, Hajós M. Modulation of hippocampal neuronal network oscillations by α7 nACh receptors. Biochemical Pharmacology. 97: 445-53. PMID 26206189 DOI: 10.1016/J.Bcp.2015.06.031 |
0.771 |
|
| 2015 |
Stoiljkovic M, Leventhal L, Chen A, Chen T, Driscoll R, Flood D, Hodgdon H, Hurst R, Nagy D, Piser T, Tang C, Townsend M, Tu Z, Bertrand D, Koenig G, et al. Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays. Biochemical Pharmacology. PMID 26206187 DOI: 10.1016/J.Bcp.2015.07.006 |
0.462 |
|
| 2015 |
Shaffer CL, Patel NC, Schwarz J, Scialis RJ, Wei Y, Hou XJ, Xie L, Karki K, Bryce DK, Osgood SM, Hoffmann WE, Lazzaro JT, Chang C, McGinnis DF, Lotarski SM, et al. The Discovery and Characterization of the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Potentiator N-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242). Journal of Medicinal Chemistry. 58: 4291-308. PMID 25905800 DOI: 10.1021/Acs.Jmedchem.5B00300 |
0.322 |
|
| 2015 |
Nagy D, Tingley FD, Stoiljkovic M, Hajós M. Application of neurophysiological biomarkers for Huntington's disease: evaluating a phosphodiesterase 9A inhibitor. Experimental Neurology. 263: 122-31. PMID 25315303 DOI: 10.1016/J.Expneurol.2014.10.001 |
0.392 |
|
| 2015 |
Hajos M. Stimulation-induced neuronal oscillations: Evaluating cognitive effects of drug treatment Brain Stimulation. 8: 419. DOI: 10.1016/J.Brs.2015.01.337 |
0.359 |
|
| 2014 |
Kozak R, Campbell BM, Strick CA, Horner W, Hoffmann WE, Kiss T, Chapin DS, McGinnis D, Abbott AL, Roberts BM, Fonseca K, Guanowsky V, Young DA, Seymour PA, Dounay A, ... Hajos M, et al. Reduction of brain kynurenic acid improves cognitive function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10592-602. PMID 25100593 DOI: 10.1523/Jneurosci.1107-14.2014 |
0.367 |
|
| 2013 |
Shaffer CL, Hurst RS, Scialis RJ, Osgood SM, Bryce DK, Hoffmann WE, Lazzaro JT, Hanks AN, Lotarski S, Weber ML, Liu J, Menniti FS, Schmidt CJ, Hajós M. Positive allosteric modulation of AMPA receptors from efficacy to toxicity: the interspecies exposure-response continuum of the novel potentiator PF-4778574. The Journal of Pharmacology and Experimental Therapeutics. 347: 212-24. PMID 23899905 DOI: 10.1124/Jpet.113.204735 |
0.374 |
|
| 2013 |
Harvey BD, Siok CJ, Kiss T, Volfson D, Grimwood S, Shaffer CL, Hajós M. Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors. Neuropharmacology. 75: 19-30. PMID 23831682 DOI: 10.1016/J.Neuropharm.2013.06.020 |
0.405 |
|
| 2013 |
Hajós M, Morozova E, Siok C, Atchison K, Nolan CE, Riddell D, Kiss T, Hajós-Korcsok E. Effects of the γ-secretase inhibitor semagacestat on hippocampal neuronal network oscillation. Frontiers in Pharmacology. 4: 72. PMID 23785331 DOI: 10.3389/Fphar.2013.00072 |
0.475 |
|
| 2013 |
Kocsis B, Brown RE, McCarley RW, Hajos M. Impact of ketamine on neuronal network dynamics: translational modeling of schizophrenia-relevant deficits. Cns Neuroscience & Therapeutics. 19: 437-47. PMID 23611295 DOI: 10.1111/Cns.12081 |
0.373 |
|
| 2013 |
Kiss T, Feng J, Hoffmann WE, Shaffer CL, Hajós M. Rhythmic theta and delta activity of cortical and hippocampal neuronal networks in genetically or pharmacologically induced N-methyl-D-aspartate receptor hypofunction under urethane anesthesia. Neuroscience. 237: 255-67. PMID 23396086 DOI: 10.1016/J.Neuroscience.2013.01.058 |
0.439 |
|
| 2013 |
Ly S, Pishdari B, Lok LL, Hajos M, Kocsis B. Activation of 5-HT6 receptors modulates sleep-wake activity and hippocampal theta oscillation. Acs Chemical Neuroscience. 4: 191-9. PMID 23336058 DOI: 10.1021/Cn300184T |
0.332 |
|
| 2012 |
Claffey MM, Helal CJ, Verhoest PR, Kang Z, Fors KS, Jung S, Zhong J, Bundesmann MW, Hou X, Lui S, Kleiman RJ, Vanase-Frawley M, Schmidt AW, Menniti F, Schmidt CJ, ... ... Hajos M, et al. Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors. Journal of Medicinal Chemistry. 55: 9055-68. PMID 23025719 DOI: 10.1021/Jm3009635 |
0.318 |
|
| 2012 |
Johnson DE, Drummond E, Grimwood S, Sawant-Basak A, Miller E, Tseng E, McDowell LL, Vanase-Frawley MA, Fisher KE, Rubitski DM, Stutzman-Engwall KJ, Nelson RT, Horner WE, Gorczyca RR, Hajos M, et al. The 5-hydroxytryptamine4 receptor agonists prucalopride and PRX-03140 increase acetylcholine and histamine levels in the rat prefrontal cortex and the power of stimulated hippocampal θ oscillations. The Journal of Pharmacology and Experimental Therapeutics. 341: 681-91. PMID 22408061 DOI: 10.1124/Jpet.112.192351 |
0.396 |
|
| 2012 |
Kleiman RJ, Chapin DS, Christoffersen C, Freeman J, Fonseca KR, Geoghegan KF, Grimwood S, Guanowsky V, Hajós M, Harms JF, Helal CJ, Hoffmann WE, Kocan GP, Majchrzak MJ, McGinnis D, et al. Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo. The Journal of Pharmacology and Experimental Therapeutics. 341: 396-409. PMID 22328573 DOI: 10.1124/Jpet.111.191353 |
0.387 |
|
| 2012 |
Scott L, Feng J, Kiss T, Needle E, Atchison K, Kawabe TT, Milici AJ, Hajós-Korcsok E, Riddell D, Hajós M. Age-dependent disruption in hippocampal θ oscillation in amyloid-β overproducing transgenic mice. Neurobiology of Aging. 33: 1481.e13-23. PMID 22227005 DOI: 10.1016/J.Neurobiolaging.2011.12.010 |
0.433 |
|
| 2011 |
Kiss T, Hoffmann WE, Scott L, Kawabe TT, Milici AJ, Nilsen EA, Hajós M. Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity. Frontiers in Psychiatry. 2: 14. PMID 21556284 DOI: 10.3389/Fpsyt.2011.00014 |
0.423 |
|
| 2011 |
Barry RJ, Clarke AR, Hajos M, Dupuy FE, McCarthy R, Selikowitz M. EEG coherence and symptom profiles of children with Attention-Deficit/Hyperactivity Disorder. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 122: 1327-32. PMID 21310652 DOI: 10.1016/J.Clinph.2011.01.007 |
0.347 |
|
| 2011 |
Sörman E, Wang D, Hajos M, Kocsis B. Control of hippocampal theta rhythm by serotonin: role of 5-HT2c receptors. Neuropharmacology. 61: 489-94. PMID 21281651 DOI: 10.1016/J.Neuropharm.2011.01.029 |
0.413 |
|
| 2011 |
Kiss T, Hoffmann WE, Hajós M. Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 29-42. PMID 20334724 DOI: 10.1017/S1461145710000271 |
0.391 |
|
| 2011 |
Roof R, Siok C, Hajos M, Cianfrogna J, Chang C, Leung L, Duplantier A, Brodney M, McDowell L, Prior F, Vanase-Frawley M, McGinnis D, Kozak R, Seymour P, Leurent C, et al. A selective ORL1 antagonist enhances hippocampal function and reverses pharmacologically induced cognitive deficits in rodents Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2220 |
0.36 |
|
| 2011 |
Hajos M, Feng J, Scott L, Harvey B, Siok C, Kawabe T, Milici A, Needle E, Hirst W, Atchison K, Riddell D, Kiss T, Hajos-Korcsok E. Age-dependent disruption in hippocampal theta oscillation in APP/PS1 mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1661 |
0.345 |
|
| 2010 |
Hajós M. Challenges in progressing schizophrenia therapy. Frontiers in Psychiatry. 1: 9. PMID 21423421 DOI: 10.3389/Fpsyt.2010.00009 |
0.305 |
|
| 2010 |
Barry RJ, Clarke AR, Hajos M, McCarthy R, Selikowitz M, Dupuy FE. Resting-state EEG gamma activity in children with attention-deficit/hyperactivity disorder. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 121: 1871-7. PMID 20483659 DOI: 10.1016/J.Clinph.2010.04.022 |
0.336 |
|
| 2010 |
O'Donnell CJ, Rogers BN, Bronk BS, Bryce DK, Coe JW, Cook KK, Duplantier AJ, Evrard E, Hajós M, Hoffmann WE, Hurst RS, Maklad N, Mather RJ, McLean S, Nedza FM, et al. Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models. Journal of Medicinal Chemistry. 53: 1222-37. PMID 20043678 DOI: 10.1021/Jm9015075 |
0.361 |
|
| 2010 |
Hajós M, Rogers BN. Targeting alpha7 nicotinic acetylcholine receptors in the treatment of schizophrenia. Current Pharmaceutical Design. 16: 538-54. PMID 19909231 DOI: 10.2174/138161210790361434 |
0.346 |
|
| 2009 |
Barry RJ, Clarke AR, Hajos M, McCarthy R, Selikowitz M, Bruggemann JM. Acute atomoxetine effects on the EEG of children with attention-deficit/hyperactivity disorder. Neuropharmacology. 57: 702-7. PMID 19698723 DOI: 10.1016/J.Neuropharm.2009.08.003 |
0.357 |
|
| 2009 |
Rollema H, Hajós M, Seymour PA, Kozak R, Majchrzak MJ, Guanowsky V, Horner WE, Chapin DS, Hoffmann WE, Johnson DE, McLean S, Freeman J, Williams KE. Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition. Biochemical Pharmacology. 78: 813-24. PMID 19501054 DOI: 10.1016/J.Bcp.2009.05.033 |
0.361 |
|
| 2008 |
Satta R, Maloku E, Zhubi A, Pibiri F, Hajos M, Costa E, Guidotti A. Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 16356-61. PMID 18852456 DOI: 10.1073/Pnas.0808699105 |
0.37 |
|
| 2008 |
Acker BA, Jacobsen EJ, Rogers BN, Wishka DG, Reitz SC, Piotrowski DW, Myers JK, Wolfe ML, Groppi VE, Thornburgh BA, Tinholt PM, Walters RR, Olson BA, Fitzgerald L, Staton BA, ... ... Hajos M, et al. Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity. Bioorganic & Medicinal Chemistry Letters. 18: 3611-5. PMID 18490160 DOI: 10.1016/J.Bmcl.2008.04.070 |
0.32 |
|
| 2008 |
Schmidt CJ, Chapin DS, Cianfrogna J, Corman ML, Hajos M, Harms JF, Hoffman WE, Lebel LA, McCarthy SA, Nelson FR, Proulx-LaFrance C, Majchrzak MJ, Ramirez AD, Schmidt K, Seymour PA, et al. Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. The Journal of Pharmacology and Experimental Therapeutics. 325: 681-90. PMID 18287214 DOI: 10.1124/Jpet.107.132910 |
0.3 |
|
| 2007 |
Ujfalussy B, Kiss T, Orbán G, Hoffmann WE, Erdi P, Hajós M. Pharmacological and computational analysis of alpha-subunit preferential GABA(A) positive allosteric modulators on the rat septo-hippocampal activity. Neuropharmacology. 52: 733-43. PMID 17113111 DOI: 10.1016/J.Neuropharm.2006.09.022 |
0.406 |
|
| 2006 |
Walker DP, Wishka DG, Piotrowski DW, Jia S, Reitz SC, Yates KM, Myers JK, Vetman TN, Margolis BJ, Jacobsen EJ, Acker BA, Groppi VE, Wolfe ML, Thornburgh BA, Tinholt PM, ... ... Hajos M, et al. Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists. Bioorganic & Medicinal Chemistry. 14: 8219-48. PMID 17011782 DOI: 10.1016/J.Bmc.2006.09.019 |
0.304 |
|
| 2006 |
Wishka DG, Walker DP, Yates KM, Reitz SC, Jia S, Myers JK, Olson KL, Jacobsen EJ, Wolfe ML, Groppi VE, Hanchar AJ, Thornburgh BA, Cortes-Burgos LA, Wong EH, Staton BA, ... ... Hajos M, et al. Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship. Journal of Medicinal Chemistry. 49: 4425-36. PMID 16821801 DOI: 10.1021/Jm0602413 |
0.362 |
|
| 2006 |
Hajós M. Targeting information-processing deficit in schizophrenia: a novel approach to psychotherapeutic drug discovery. Trends in Pharmacological Sciences. 27: 391-8. PMID 16766049 DOI: 10.1016/J.Tips.2006.05.005 |
0.392 |
|
| 2005 |
Bodnar AL, Cortes-Burgos LA, Cook KK, Dinh DM, Groppi VE, Hajos M, Higdon NR, Hoffmann WE, Hurst RS, Myers JK, Rogers BN, Wall TM, Wolfe ML, Wong E. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 48: 905-8. PMID 15715459 DOI: 10.1021/Jm049363Q |
0.404 |
|
| 2005 |
Hajós M, Hurst RS, Hoffmann WE, Krause M, Wall TM, Higdon NR, Groppi VE. The selective α7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats Journal of Pharmacology and Experimental Therapeutics. 312: 1213-1222. PMID 15523001 DOI: 10.1124/Jpet.104.076968 |
0.454 |
|
| 2004 |
Hajós M, Hoffmann WE, Orbán G, Kiss T, Erdi P. Modulation of septo-hippocampal Theta activity by GABAA receptors: an experimental and computational approach. Neuroscience. 126: 599-610. PMID 15183510 DOI: 10.1016/J.Neuroscience.2004.03.043 |
0.443 |
|
| 2003 |
Hajós M, Hoffmann WE, Weaver RJ. Regulation of septo-hippocampal activity by 5-hydroxytryptamine2C receptors Journal of Pharmacology and Experimental Therapeutics. 306: 605-615. PMID 12734389 DOI: 10.1124/Jpet.103.051169 |
0.449 |
|
| 2003 |
Hajós M, Hoffmann WE, Robinson DD, Yu JH, Hajós-Korcsok E. Norepinephrine but not serotonin reuptake inhibitors enhance theta and gamma activity of the septo-hippocampal system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 857-64. PMID 12637957 DOI: 10.1038/Sj.Npp.1300116 |
0.414 |
|
| 2003 |
Krause M, Hoffmann WE, Hajós M. Auditory sensory gating in hippocampus and reticular thalamic neurons in anesthetized rats Biological Psychiatry. 53: 244-253. PMID 12559658 DOI: 10.1016/S0006-3223(02)01463-4 |
0.376 |
|
| 2000 |
Erhardt S, Hajos M, Lindberg A, Engberg G. Nicotine-induced excitation of locus coeruleus neurons is blocked by elevated levels of endogenous kynurenic acid. Synapse. 37: 104-108. PMID 10881031 DOI: 10.1002/1098-2396(200008)37:2<104::Aid-Syn4>3.0.Co;2-L |
0.397 |
|
| 1999 |
Horvath TL, Warden CH, Hajos M, Lombardi A, Goglia F, Diano S. Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10417-27. PMID 10575039 DOI: 10.1523/Jneurosci.19-23-10417.1999 |
0.325 |
|
| 1997 |
Hajós M, Sharp T. Burst-firing activity of presumed 5-HT neurones of the rat dorsal raphe nucleus: electrophysiological analysis by antidromic stimulation. Brain Research. 740: 162-8. PMID 8973810 DOI: 10.1016/S0006-8993(96)00869-4 |
0.359 |
|
| 1997 |
Hajos M, Sharp T. A 5-hydroxytryptamine lesion markedly reduces the incidence of burst-firing dorsal raphe neurones in the rat. Neuroscience Letters. 204: 161-4. PMID 8938255 DOI: 10.1016/0304-3940(96)12333-8 |
0.337 |
|
| 1997 |
Hajós M, Sharp T, Newberry NR. Intracellular recordings from burst-firing presumed serotonergic neurones in the rat dorsal raphe nucleus in vivo. Brain Research. 737: 308-12. PMID 8930381 DOI: 10.1016/0006-8993(96)00936-5 |
0.374 |
|
| 1996 |
Hajós M, Gartside SE, Villa AE, Sharp T. Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat. Neuroscience. 69: 189-97. PMID 8637617 DOI: 10.1016/0306-4522(95)00227-A |
0.371 |
|
| 1995 |
Hajós M, Gartside SE, Sharp T. Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine. Naunyn-Schmiedeberg's Archives of Pharmacology. 351: 624-9. PMID 7675121 DOI: 10.1007/Bf00170162 |
0.366 |
|
| 1994 |
Engbergl G, Hajos M. Nicotine-induced activation of locus coeruleus neurons--an analysis of peripheral versus central induction. Naunyn-Schmiedebergs Archives of Pharmacology. 349: 443-446. PMID 8065457 DOI: 10.1007/Bf00169131 |
0.359 |
|
| 1993 |
Hajós M, Greenfield SA. Topographic heterogeneity of substantia nigra neurons: Diversity in intrinsic membrane properties and synaptic inputs Neuroscience. 55: 919-934. PMID 7901802 DOI: 10.1016/0306-4522(93)90308-3 |
0.392 |
|
| 1992 |
Hajós M, Greenfield S. Differential actions of acetylcholinesterase on the soma and dendrites of dopaminergic substantia nigra neurons in vitro Brain Research. 585: 416-420. PMID 1511329 DOI: 10.1016/0006-8993(92)91248-D |
0.361 |
|
| 1992 |
Engberg G, Hajós M. Alcohol withdrawal reaction as a result of adaptive changes of excitatory amino acid receptors. Naunyn-Schmiedebergs Archives of Pharmacology. 346: 437-441. PMID 1436128 DOI: 10.1007/Bf00171087 |
0.331 |
|
| 1992 |
Engberg G, Hajós M. Ethanol attenuates the response of locus coeruleus neurons to excitatory amino acid agonists in vivo Naunyn-Schmiedebergs Archives of Pharmacology. 345: 222-226. PMID 1314963 DOI: 10.1007/Bf00165740 |
0.316 |
|
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