Candece Gladson, M.D. - Publications

Affiliations: 
Cancer Biology Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States 
Area:
TNF-R1, FIP200, malignant gliomas
Website:
http://www.lerner.ccf.org/cancerbio/gladson/

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Bae E, Huang P, Müller-Greven G, Hambardzumyan D, Sloan AE, Nowacki AS, Marko N, Carlin CR, Gladson CL. Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis. Nature Communications. 13: 4268. PMID 35879332 DOI: 10.1038/s41467-022-31981-2  0.666
2018 Hashemi-Sadraei N, Müller-Greven GM, Abdul-Karim FW, Ulasov I, Downs-Kelly E, Burgett ME, Lauko A, Qadan MA, Weil RJ, Ahluwalia MS, Du L, Prayson RA, Chao ST, Budd TG, Barnholtz-Sloan J, ... ... Gladson CL, et al. Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer. Journal of Neuro-Oncology. PMID 30094720 DOI: 10.1007/S11060-018-2959-5  0.749
2018 Muller-Greven G, Marin B, Carlin C, Reilly E, Lee J, Bredel M, Sarkaria J, Gladson C. CADD-57. THE EFFICACY OF THERAPY WITH ABT-414, AN EGFR-TARGETING ADC, IS POTENTIALLY ALTERED BY HETEROZYGOUS DELETION OF THE ENDOCYTIC TRAFFICKING REGULATOR RBSN Neuro-Oncology. 20: vi283-vi284. DOI: 10.1093/Neuonc/Noy148.1182  0.725
2017 Müller-Greven GM, Carlin C, Burgett ME, Ahluwalia MS, Lauko A, Nowacki AS, Herting CJ, Qadan MA, Bredel M, Toms SA, Lathia JD, Hambardzumyan D, Sarkaria JN, Hamerlik P, Gladson CL. Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28912141 DOI: 10.1158/1078-0432.Ccr-17-0249  0.774
2016 Ahluwalia MS, Bou-Anak S, Burgett ME, Sarmey N, Khosla D, Dahiya S, Weil RJ, Bae E, Huang P, McGraw M, Grove LM, Olman MA, Prayson RA, Suh JH, Gillespie GY, ... ... Gladson CL, et al. Correlation of higher levels of soluble TNF-R1 with a shorter survival, independent of age, in recurrent glioblastoma. Journal of Neuro-Oncology. PMID 27858267 DOI: 10.1007/S11060-016-2319-2  0.734
2016 Burgett ME, Lathia JD, Roth P, Nowacki AS, Galileo DS, Pugacheva E, Huang P, Vasanji A, Li M, Byzova T, Mikkelsen T, Bao S, Rich JN, Weller M, Gladson CL. Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells. Oncotarget. PMID 27270311 DOI: 10.18632/Oncotarget.9700  0.755
2016 Burgett M, Nowacki A, Lathia J, Rich J, Gladson C. TMIC-27. CONTACT-INDUCED BI-DIRECTIONAL PRO-SURVIVAL SIGNALING BETWEEN ENDOTHELIAL CELLS AND CANCER STEM-LIKE CELLS IN GLIOBLASTOMA Neuro-Oncology. 18: vi205-vi206. DOI: 10.1093/Neuonc/Now212.867  0.707
2016 Muller-Greven G, Carlin C, Toms S, Ahluwalia MS, Bredel M, Lathia J, Rich J, Hamerlik P, Gladson C. STMC-30. TRAFFICKING AND EFFECT ON SURVIVAL OF BEVACIZUMAB IN GLIOBLASTOMA Neuro-Oncology. 18: vi188-vi189. DOI: 10.1093/Neuonc/Now212.793  0.758
2015 Muller-Greven G, Carlin C, Toms S, Ahluwalia M, Bredel M, Lathia J, Rich J, Hamerlik P, Gladson CL. STEM-12FATE OF BEVACIZUMAB IN GLIOBLASTOMA Neuro-Oncology. 17: v210.4-v210. DOI: 10.1093/Neuonc/Nov234.12  0.739
2014 Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, ... ... Gladson CL, et al. Cancer stem cell-specific scavenger receptor 36 drives glioblastoma progression. Stem Cells (Dayton, Ohio). 32: 1746-58. PMID 24737733 DOI: 10.1002/Stem.1716  0.421
2014 Muller-Greven G, Carlin C, Lathia J, Rich J, Hamerlik P, Gladson C. SC-22 * GLIOMA STEM CELLS INTERNALIZE BEVACIZUMAB FOUND IN THE PERIVASCULAR NICHE AND TARGET IT FOR RECYCLING OR DEGRADATION Neuro-Oncology. 16: v201-v201. DOI: 10.1093/Neuonc/Nou275.22  0.8
2014 Bae E, Smith L, Muller-Greven G, Yamada R, Joshi K, Nakano-Okuno M, Feng X, Hambardzumyan D, Nakano I, Gladson CL. AI-03 * TARGETING ANGIOGENESIS WITHOUT INCREASING THE STROMAL CELL RESPONSE OR INVASION USING ABT-898, A THROMBOSPONDIN TYPE 1 REPEAT PEPTIDE Neuro-Oncology. 16: v1-v1. DOI: 10.1093/Neuonc/Nou238.3  0.792
2014 Gladson CL, Burgett ME, Lathia JD, Roth P, Huang P, Vasanji A, Li M, Bao S, Nowacki A, RIch JN, Weller M. DIRECT CELL CONTACT BETWEEN BRAIN ENDOTHELIAL CELLS AND GLIOMA STEM CELLS PROMOTES ENDOTHELIAL CELL MIGRATION Neuro-Oncology. 16: iii36-iii36. DOI: 10.1093/Neuonc/Nou208.49  0.724
2013 Liu WM, Huang P, Kar N, Burgett M, Muller-Greven G, Nowacki AS, Distelhorst CW, Lathia JD, Rich JN, Kappes JC, Gladson CL. Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy. Plos One. 8: e70804. PMID 23936469 DOI: 10.1371/Journal.Pone.0070804  0.774
2012 Lathia JD, Li M, Hall PE, Gallagher J, Hale JS, Wu Q, Venere M, Levy E, Rani MR, Huang P, Bae E, Selfridge J, Cheng L, Guvenc H, McLendon RE, ... ... Gladson CL, et al. Laminin alpha 2 enables glioblastoma stem cell growth. Annals of Neurology. 72: 766-78. PMID 23280793 DOI: 10.1002/Ana.23674  0.696
2012 Robles Irizarry L, Hambardzumyan D, Nakano I, Gladson CL, Ahluwalia MS. Therapeutic targeting of VEGF in the treatment of glioblastoma. Expert Opinion On Therapeutic Targets. 16: 973-84. PMID 22876981 DOI: 10.1517/14728222.2012.711817  0.318
2012 Huang P, Rani MR, Ahluwalia MS, Bae E, Prayson RA, Weil RJ, Nowacki AS, Hedayat H, Sloan AE, Lathia JD, Rich JN, Tipps R, Gladson CL. Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma. Cancer Research. 72: 1428-37. PMID 22396498 DOI: 10.1158/0008-5472.Can-11-2621  0.663
2012 Hashemi Sadraei N, Ulasov I, Burgett M, Nowacki AS, Prayson R, Weil RJ, Kar N, Ahluwalia MS, Muller-Greven G, Shi T, Lesniak MS, Gladson C. FIP200 and Rb1 expression in CNS metastasis from breast cancer (CNS met): Potential predictors of patient outcome. Journal of Clinical Oncology. 30: 2014-2014. DOI: 10.1200/Jco.2012.30.15_Suppl.2014  0.707
2012 Kozono D, Nitta M, Sampetrean O, Kimberly N, Kushwaha D, Merzon D, Ligon K, Zhu S, Zhu K, Kim TH, Kwon C, Becher O, Saya H, Chen CC, Donovan LK, ... ... Gladson C, ... ... Gladson C, et al. LAB-STEM CELLS Neuro-Oncology. 14: vi142-vi152. DOI: 10.1093/Neuonc/Nos239  0.626
2012 Noch E, Pina-Oviedo S, Perez-Liz G, Bookland M, Del Valle L, Gordon J, Khalili K, Juratli TA, Peitzsch M, Geiger K, Schackert G, Eisenhofer G, Krex D, Chaumeil MM, Woods SM, ... ... Gladson C, et al. LAB-METABOLIC PATHWAYS Neuro-Oncology. 14: vi53-vi55. DOI: 10.1093/Neuonc/Nos226  0.34
2012 Proescholdt MA, Merrill MJ, Stoerr E, Lohmeier A, Brawanski A, Sim H, Hu B, Pineda CA, Yoon S, Viapiano MS, Rajappa P, Cobb WS, Huang Y, Lyden DC, Bromberg J, ... ... Gladson CL, et al. LAB-ANGIOGENESIS AND INVASION Neuro-Oncology. 14: vi1-vi6. DOI: 10.1093/Neuonc/Nos219  0.735
2011 Burgett M, Hashemi Sadraei N, Ahluwalia MS, Tipps R, Khosla D, Nowacki AS, Weil R, Prayson R, Gladson C. Expression (Exp) of FIP200 and Rb in breast cancer (BreastCA) metastasis (met) to the brain and effect on survival. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e21152. PMID 28022692 DOI: 10.1200/Jco.2011.29.15_Suppl.E21152  0.722
2011 Hashemi Sadraei N, Burgett M, Ahluwalia MS, Tipps R, Khosla D, Weil R, Nowaki A, Prayson R, Shi T, Gladson C. Expression (Exp) of FIP200 and Rb in breast cancer (BreastCA) metastasis (met) to the brain. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 222. PMID 27958119 DOI: 10.1200/Jco.2011.29.27_Suppl.222  0.716
2011 Wang D, Olman MA, Stewart J, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan JL, ... Gladson CL, et al. Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity. Plos One. 6: e19629. PMID 21602932 DOI: 10.1371/Journal.Pone.0019629  0.535
2010 Ahluwalia MS, de Groot J, Liu WM, Gladson CL. Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies. Cancer Letters. 298: 139-49. PMID 20947248 DOI: 10.1016/j.canlet.2010.08.014  0.317
2010 Ahluwalia MS, Gladson CL. Progress on antiangiogenic therapy for patients with malignant glioma. Journal of Oncology. 2010: 689018. PMID 20379377 DOI: 10.1155/2010/689018  0.399
2010 Klenotic PA, Huang P, Palomo J, Kaur B, Van Meir EG, Vogelbaum MA, Febbraio M, Gladson CL, Silverstein RL. Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. The American Journal of Pathology. 176: 2039-50. PMID 20167858 DOI: 10.2353/Ajpath.2010.090782  0.508
2009 McFarland BC, Stewart J, Hamza A, Nordal R, Davidson DJ, Henkin J, Gladson CL. Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1. Cancer Research. 69: 5537-45. PMID 19549899 DOI: 10.1158/0008-5472.CAN-08-4841  0.304
2007 Anderson JC, Grammer JR, Wang W, Nabors LB, Henkin J, Stewart JE, Gladson CL. ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis. Cancer Biology & Therapy. 6: 454-62. PMID 17384534  0.344
2006 Fears CY, Gladson CL, Woods A. Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells. The Journal of Biological Chemistry. 281: 14533-6. PMID 16574663 DOI: 10.1074/Jbc.C600075200  0.333
2006 Akella NS, Ding Q, Menegazzo I, Wang W, Gillespie GY, Grammer JR, Gladson CL, Nabors LB. A novel technique to quantify glioma tumor invasion using serial microscopy sections. Journal of Neuroscience Methods. 153: 183-9. PMID 16406041 DOI: 10.1016/J.Jneumeth.2005.10.026  0.32
2006 Natarajan M, Stewart JE, Golemis EA, Pugacheva EN, Alexandropoulos K, Cox BD, Wang W, Grammer JR, Gladson CL. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene. 25: 1721-32. PMID 16288224 DOI: 10.1038/Sj.Onc.1209199  0.331
2005 Wang D, Anderson JC, Gladson CL. The role of the extracellular matrix in angiogenesis in malignant glioma tumors. Brain Pathology (Zurich, Switzerland). 15: 318-26. PMID 16389944  0.39
2005 Rege TA, Fears CY, Gladson CL. Endogenous inhibitors of angiogenesis in malignant gliomas: nature's antiangiogenic therapy. Neuro-Oncology. 7: 106-21. PMID 15831230 DOI: 10.1215/S115285170400119X  0.303
2004 Rosenthal E, McCrory A, Talbert M, Young G, Murphy-Ullrich J, Gladson C. Elevated expression of TGF-beta1 in head and neck cancer-associated fibroblasts. Molecular Carcinogenesis. 40: 116-21. PMID 15170816 DOI: 10.1002/Mc.20024  0.353
2003 Rosenthal EL, Shreenivas S, Peters GE, Grizzle WE, Desmond R, Gladson CL. Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma. The Laryngoscope. 113: 1406-10. PMID 12897567 DOI: 10.1097/00005537-200308000-00027  0.318
2003 Haskell H, Natarajan M, Hecker TP, Ding Q, Stewart J, Grammer JR, Gladson CL. Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2157-65. PMID 12796381  0.379
2003 Natarajan M, Hecker TP, Gladson CL. FAK signaling in anaplastic astrocytoma and glioblastoma tumors. Cancer Journal (Sudbury, Mass.). 9: 126-33. PMID 12784878 DOI: 10.1097/00130404-200303000-00008  0.335
2003 Hecker TP, Gladson CL. Focal adhesion kinase in cancer. Frontiers in Bioscience : a Journal and Virtual Library. 8: s705-14. PMID 12700131  0.357
2002 Ding Q, Stewart J, Prince CW, Chang PL, Trikha M, Han X, Grammer JR, Gladson CL. Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin versus vitronectin. Cancer Research. 62: 5336-43. PMID 12235004  0.373
2001 Wong AJ, Padarathsingh M, Louis DN, Rempel S, Ladisch S, Gladson C. New approaches to the molecular biology, classification, and therapy of nervous system tumors: a workshop of the National Institutes of Health Pathology B study section. The American Journal of Pathology. 159: 1971-4. PMID 11696458 DOI: 10.1016/S0002-9440(10)63044-1  0.411
2000 Wang D, Grammer JR, Cobbs CS, Stewart JE, Liu Z, Rhoden R, Hecker TP, Ding Q, Gladson CL. p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo. Journal of Cell Science. 113: 4221-30. PMID 11069767  0.399
1999 Jennelle R, Gladson C, Palmer C, Guthrie B, Markert J. Paradoxical labeling of radiosurgically treated quiescent tumors with Ki67, a marker of cellular proliferation. Stereotactic and Functional Neurosurgery. 72: 45-52. PMID 10681690  0.335
1999 Gladson CL. The extracellular matrix of gliomas: modulation of cell function. Journal of Neuropathology and Experimental Neurology. 58: 1029-40. PMID 10515226  0.338
1999 Mohan PM, Chintala SK, Mohanam S, Gladson CL, Kim ES, Gokaslan ZL, Lakka SS, Roth JA, Fang B, Sawaya R, Kyritsis AP, Rao JS. Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth. Cancer Research. 59: 3369-73. PMID 10416596  0.338
1999 Uhm JH, Dooley NP, Kyritsis AP, Rao JS, Gladson CL. Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 1587-94. PMID 10389948  0.359
1999 Uhm JH, Gladson CL, Rao JS. The role of integrins in the malignant phenotype of gliomas. Frontiers in Bioscience : a Journal and Virtual Library. 4: D188-99. PMID 9989953  0.332
1999 Mohanam S, Gladson CL, Rao CN, Rao JS. Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors. Frontiers in Bioscience : a Journal and Virtual Library. 4: D178-87. PMID 9989951  0.416
1995 Singh RK, Hardy RW, Wang MH, Williford J, Gladson CL, McDonald JM, Siegal GP. Stearate inhibits human tumor cell invasion. Invasion & Metastasis. 15: 144-55. PMID 8621270  0.344
1995 Gladson CL, Wilcox JN, Sanders L, Gillespie GY, Cheresh DA. Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors. Journal of Cell Science. 108: 947-56. PMID 7542670  0.314
1995 Gladson CL, Dennis C, Sampathkumar S, Hancock S. VITRONECTIN SYNTHESIS BY NEUROBLASTOMA CELLS IN VIVO IS INDEPENDENT OF TUMOR DIFFERENTIATION Journal of Neuropathology and Experimental Neurology. 54: 456. DOI: 10.1097/00005072-199505000-00195  0.339
1991 Schrappe M, Klier FG, Spiro RC, Waltz TA, Reisfeld RA, Gladson CL. Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells. Cancer Research. 51: 4986-93. PMID 1893386  0.404
1991 Gladson CL, Cheresh DA. Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. The Journal of Clinical Investigation. 88: 1924-32. PMID 1721625 DOI: 10.1172/Jci115516  0.357
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