Nigel Greig - Related publications

Affiliations: 
Drug Design and Development National Institute of Aging, Cabanatuan City, Central Luzon, Philippines 
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27 most relevant papers in past 60 days:
Year Citation  Score
2022 Tang JJ, Huang LF, Deng JL, Wang YM, Guo C, Peng XN, Liu Z, Gao JM. Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model. Redox Biology. 50: 102229. PMID 35026701 DOI: 10.1016/j.redox.2022.102229   
2022 Asih PR, Stefanoska K, Prikas E, Ittner A. High level forebrain expression of active tau kinase p38γ exacerbates cognitive dysfunction in aged APP-transgenic alzheimer's mice. Neuroscience. PMID 35031398 DOI: 10.1016/j.neuroscience.2022.01.005   
2022 Pons V, Rivest S. Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease. Pharmacological Reviews. 74: 1-17. PMID 34987086 DOI: 10.1124/pharmrev.121.000400   
2022 Thuraisingham RA. A kinetic scheme to examine the role of glial cells in the pathogenesis of Alzheimer's disease. Metabolic Brain Disease. PMID 35032278 DOI: 10.1007/s11011-022-00902-z   
2022 Lin L, Hua F, Salinas C, Young C, Bussiere T, Apgar JF, Burke JM, Muralidharan K, Rajagovindan R, Nestorov I. Quantitative systems pharmacology model for Alzheimer's disease to predict effect of aducanumab on brain amyloid. Cpt: Pharmacometrics & Systems Pharmacology. PMID 35029320 DOI: 10.1002/psp4.12759   
2022 Zamanian J, Khoshbin Z, Abnous K, Taghdisi SM, Hosseinzadeh H, Danesh NM. Current progress in aptamer-based sensing tools for ultra-low level monitoring of Alzheimer's disease biomarkers. Biosensors & Bioelectronics. 197: 113789. PMID 34798498 DOI: 10.1016/j.bios.2021.113789   
2022 Campos HC, Ribeiro DE, Hashiguchi D, Hukuda DY, Gimenes C, Romariz SAA, Ye Q, Tang Y, Ulrich H, Longo BM. Distinct Effects of the Hippocampal Transplantation of Neural and Mesenchymal Stem Cells in a Transgenic Model of Alzheimer's Disease. Stem Cell Reviews and Reports. PMID 34997526 DOI: 10.1007/s12015-021-10321-9   
2022 Sharma L, Sharma A, Kumar D, Asthana MK, Lalhlenmawia H, Kumar A, Bhattacharyya S, Kumar D. Promising protein biomarkers in the early diagnosis of Alzheimer's disease. Metabolic Brain Disease. PMID 35015199 DOI: 10.1007/s11011-021-00847-9   
2022 Fagan SG, Bechet S, Dev KK. Fingolimod Rescues Memory and Improves Pathological Hallmarks in the 3xTg-AD Model of Alzheimer's Disease. Molecular Neurobiology. PMID 35031916 DOI: 10.1007/s12035-021-02613-5   
2022 Frisoni GB, Altomare D, Thal DR, Ribaldi F, van der Kant R, Ossenkoppele R, Blennow K, Cummings J, van Duijn C, Nilsson PM, Dietrich PY, Scheltens P, Dubois B. The probabilistic model of Alzheimer disease: the amyloid hypothesis revised. Nature Reviews. Neuroscience. 23: 53-66. PMID 34815562 DOI: 10.1038/s41583-021-00533-w   
2022 Lee D, Park JC, Jung KS, Kim J, Jang JS, Kwon S, Byun MS, Yi D, Byeon G, Jung G, Kim YK, Lee DY, Han SH, Mook-Jung I. Application of QPLEX biomarkers in cognitively normal individuals across a broad age range and diverse regions with cerebral amyloid deposition. Experimental & Molecular Medicine. PMID 35058557 DOI: 10.1038/s12276-021-00719-3   
2022 Kamei N, Hashimoto A, Tanaka E, Murata K, Yamaguchi M, Yokoyama N, Kato M, Oki K, Saito T, Saido TC, Takeda-Morishita M. Therapeutic effects of anti-amyloid β antibody after intravenous injection and efficient nose-to-brain delivery in Alzheimer's disease mouse model. Drug Delivery and Translational Research. PMID 35015254 DOI: 10.1007/s13346-022-01117-6   
2022 Jia J, Zhang X, Xu G, Zeng X, Li L. Thioredoxin-1 inhibits amyloid-β-induced activation of NLRP1/caspase-1/GSDMD pyroptotic pathway in PC12 cells. Molecular Biology Reports. PMID 35072836 DOI: 10.1007/s11033-022-07177-8   
2022 Yu H, Shi J, Lin Y, Zhang Y, Luo Q, Huang S, Wang S, Wei J, Huang J, Li C, Ji L. Icariin Ameliorates Alzheimer's Disease Pathology by Alleviating Myelin Injury in 3 × Tg-AD Mice. Neurochemical Research. PMID 35037164 DOI: 10.1007/s11064-021-03507-7   
2022 Pinky PD, Pfitzer JC, Senfeld J, Hong H, Bhattacharya S, Suppiramaniam V, Qureshi I, Reed MN. Recent Insights on Glutamatergic Dysfunction in Alzheimer's Disease and Therapeutic Implications. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10738584211069897. PMID 35073787 DOI: 10.1177/10738584211069897   
2022 Wang C, Chen JC, Xiao HH, Kong L, Zhao YM, Tian Y, Li H, Tian JM, Cui L, Wen CM, Shi YJ, Yang JX, Shang DJ. Jujuboside A promotes proliferation and neuronal differentiation of APPswe-overexpressing neural stem cells by activating Wnt/β-catenin signaling pathway. Neuroscience Letters. 136473. PMID 35077846 DOI: 10.1016/j.neulet.2022.136473   
2022 Su IJ, Hsu CY, Shen S, Chao PK, Hsu JT, Hsueh JT, Liang JJ, Hsu YT, Shie FS. The Beneficial Effects of Combining Anti-Aβ Antibody NP106 and Curcumin Analog TML-6 on the Treatment of Alzheimer's Disease in APP/PS1 Mice. International Journal of Molecular Sciences. 23. PMID 35008983 DOI: 10.3390/ijms23010556   
2022 Xu S, Yang P, Qian K, Li Y, Guo Q, Wang P, Meng R, Wu J, Cao J, Cheng Y, Xu M, Zhang Q. Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease. Bioactive Materials. 11: 300-316. PMID 34977433 DOI: 10.1016/j.bioactmat.2021.09.017   
2022 Teunissen CE, Verberk IMW, Thijssen EH, Vermunt L, Hansson O, Zetterberg H, van der Flier WM, Mielke MM, Del Campo M. Blood-based biomarkers for Alzheimer's disease: towards clinical implementation. The Lancet. Neurology. 21: 66-77. PMID 34838239 DOI: 10.1016/S1474-4422(21)00361-6   
2022 Salloway S, Chalkias S, Barkhof F, Burkett P, Barakos J, Purcell D, Suhy J, Forrestal F, Tian Y, Umans K, Wang G, Singhal P, Budd Haeberlein S, Smirnakis K. Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease. Jama Neurology. 79: 13-21. PMID 34807243 DOI: 10.1001/jamaneurol.2021.4161   
2022 Islam S, Sun Y, Gao Y, Nakamura T, Noorani AA, Li T, Wong PC, Kimura N, Matsubara E, Kasuga K, Ikeuchi T, Tomita T, Zou K, Michikawa M. Presenilin is essential for ApoE secretion, a novel role of presenilin involved in Alzheimer's disease pathogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34987110 DOI: 10.1523/JNEUROSCI.2039-21.2021   
2022 Lee PJ, Tsai CL, Liang CS, Peng GS, Lee JT, Tsai CK, Lin YK, Yang FY. Biomarkers with Plasma Amyloid β and Tau Protein Assayed by Immunomagnetic Reduction in Patients with Amnestic Mild Cognitive Impairment and Alzheimer's Disease. Acta Neurologica Taiwanica. 31: 53-60. PMID 35040113   
2022 Smit T, Ormel PR, Sluijs JA, Hulshof LA, Middeldorp J, de Witte LD, Hol EM, Donega V. Transcriptomic and functional analysis of Aβ oligomer-stimulated human monocyte-derived microglia-like cells. Brain, Behavior, and Immunity. 100: 219-230. PMID 34896594 DOI: 10.1016/j.bbi.2021.12.001   
2022 Ning H, Zhang T, Zhou X, Liu L, Shang C, Qi R, Ma T. PART1 destabilized by NOVA2 regulates blood-brain barrier permeability in endothelial cells via STAU1-mediated mRNA degradation. Gene. 146164. PMID 34990795 DOI: 10.1016/j.gene.2021.146164   
2022 You Y, Muraoka S, Jedrychowski MP, Hu J, McQuade AK, Young-Pearse T, Aslebagh R, Shaffer SA, Gygi SP, Blurton-Jones M, Poon WW, Ikezu T. Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain. Journal of Extracellular Vesicles. 11: e12183. PMID 35029059 DOI: 10.1002/jev2.12183   
2022 Ferreira CB, Marttinen M, Coelho JE, Paldanius KMA, Takalo M, Mäkinen P, Leppänen L, Miranda-Lourenço C, Fonseca-Gomes J, Tanqueiro SR, Vaz SH, Belo RF, Sebastião AM, Leinonen V, Soininen H, et al. S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5. Neurobiology of Disease. 163: 105603. PMID 34954322 DOI: 10.1016/j.nbd.2021.105603   
2022 Liu Y, Zhang H, Peng A, Cai X, Wang Y, Tang K, Wu X, Liang Y, Wang L, Li Z. PEG-PEI/siROCK2 inhibits Aβ42-induced microglial inflammation via NLRP3/caspase 1 pathway. Neuroreport. 33: 26-32. PMID 34874326 DOI: 10.1097/WNR.0000000000001752