Aline A. dos Santos, D.Sc. - Related publications

Affiliations: 
UFRJ, Rio de Janeiro, Rio de Janeiro, Brazil 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, Lemmon MA. Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics. Science Signaling. 13. PMID 32817373 DOI: 10.1126/scisignal.aaz5267   
2020 He Y, Wu Y, Mei B, Fang X, Cai G, Cai N, Wu Q, Huang Z, Ge C, Liang H, Zhang B, Chen X, Chu L. A small nucleolar RNA, SNORD126, promotes adipogenesis in cells and rats by activating the PI3K-AKT pathway. Journal of Cellular Physiology. PMID 32960468 DOI: 10.1002/jcp.30066   
2020 Schönholzer MT, Migliavacca J, Alvarez E, Santhana Kumar K, Neve A, Gries A, Ma M, Grotzer MA, Baumgartner M. Real-time sensing of MAPK signaling in medulloblastoma cells reveals cellular evasion mechanism counteracting dasatinib blockade of ERK activation during invasion. Neoplasia (New York, N.Y.). 22: 470-483. PMID 32818841 DOI: 10.1016/j.neo.2020.07.006   
2020 Colella B, Colardo M, Iannone G, Contadini C, Saiz-Ladera C, Fuoco C, Barilà D, Velasco G, Segatto M, Di Bartolomeo S. mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells. Cancers. 12. PMID 32823532 DOI: 10.3390/cancers12082266   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 Mittal S, Kamath A, Joseph AM, Rajala MS. PLCγ1‑dependent invasion and migration of cells expressing NSCLC‑associated EGFR mutants. International Journal of Oncology. PMID 32945365 DOI: 10.3892/ijo.2020.5112   
2020 Yang HW, Jung Y, Kim HD, Kim J. Ribosomal protein S3-derived repair domain peptides regulate UV-induced matrix metalloproteinase-1. Biochemical and Biophysical Research Communications. 530: 149-154. PMID 32828277 DOI: 10.1016/j.bbrc.2020.06.094   
2020 Zhang W, Wu Y. Mitogen- and stress-activated protein kinase-1 activation is involved in melanocortin-induced BDNF expression in Neuro2a neuronal cells. Neuroreport. 31: 1007-1014. PMID 32815825 DOI: 10.1097/WNR.0000000000001508   
2020 Matsumoto S, Yokota S, Chosa N, Kyakumoto S, Kimura H, Kamo M, Satoh K, Ishisaki A. Receptor tyrosine kinase ligands and inflammatory cytokines cooperatively suppress the fibrogenic activity in temporomandibular-joint-derived fibroblast-like synoviocytes via mitogen-activated protein kinase kinase/extracellular signal-regulated kinase. Experimental and Therapeutic Medicine. 20: 1967-1974. PMID 32782506 DOI: 10.3892/etm.2020.8944   
2020 Al-Yozbaki M, Acha-Sagredo A, George A, Liloglou T, Wilson CM. Balancing neurotrophin pathway and sortilin function: Its role in human disease. Biochimica Et Biophysica Acta. Reviews On Cancer. 188429. PMID 32956766 DOI: 10.1016/j.bbcan.2020.188429   
2020 Lacey BM, Xu Z, Chai X, Laskey J, Fradera X, Mittal P, Mishra S, Piesvaux J, Saradjian P, Shaffer L, Vassileva G, Gerdt C, Wang Y, Ferguson H, Smith DM, et al. Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors. Slas Discovery : Advancing Life Sciences R & D. 2472555220952071. PMID 32844715 DOI: 10.1177/2472555220952071   
2020 Spengler K, Zibrova D, Woods A, Langendorf CG, Scott JW, Carling D, Heller R. Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. The Biochemical Journal. PMID 32869834 DOI: 10.1042/BCJ20200555   
2020 Zhang H, Lu S, Xu R, Tang Y, Liu J, Li C, Wei J, Yao R, Zhao X, Wei Q, Ma B. Mechanisms of estradiol-induced EGF-like factor expression and oocyte maturation via G protein-coupled estrogen receptor. Endocrinology. PMID 33068422 DOI: 10.1210/endocr/bqaa190   
2020 Mitchell K, Mikwar M, Da Fonte D, Lu C, Tao B, Peng D, Udeesha Erandani WKC, Hu W, Trudeau VL. Secretoneurin is a secretogranin-2 derived hormonal peptide in vertebrate neuroendocrine systems. General and Comparative Endocrinology. 113588. PMID 32828813 DOI: 10.1016/j.ygcen.2020.113588   
2020 Hirata Y, Nada Y, Yamada Y, Toyama T, Fukunaga K, Hwang GW, Noguchi T, Matsuzawa A. Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X-ROS-ASK1-p38 Axis in Microglial Cell Lines. Biological & Pharmaceutical Bulletin. 43: 1562-1569. PMID 32999166 DOI: 10.1248/bpb.b20-00409   
2020 Wang Q, Zhang Y, Zhu J, Zheng H, Chen S, Chen L, Yang HS. IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas. Signal Transduction and Targeted Therapy. 5: 153. PMID 32843616 DOI: 10.1038/s41392-020-0204-0   
2020 Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND. Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells. Biomolecules & Therapeutics. PMID 33073770 DOI: 10.4062/biomolther.2020.153   
2020 Huang JB, Hsu SP, Pan HY, Chen SD, Chen SF, Lin TK, Liu XP, Li JH, Chen NC, Liou CW, Hsu CY, Chuang HY, Chuang YC. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International Journal of Molecular Sciences. 21. PMID 33008083 DOI: 10.3390/ijms21197247   
2020 Gopallawa I, Lee RJ. Targeting the phosphoinositide-3-kinase/protein kinase B pathway in airway innate immunity. World Journal of Biological Chemistry. 11: 30-51. PMID 33024516 DOI: 10.4331/wjbc.v11.i2.30   
2020 Zhao L, Geng T, Sun K, Su S, Zhao Y, Bao N, Pan L, Sun H, Li M. Proteomic analysis reveals the molecular mechanism of Hippophae rhamnoides polysaccharide intervention in LPS-induced inflammation of IPEC-J2 cells in piglets. International Journal of Biological Macromolecules. PMID 32888998 DOI: 10.1016/j.ijbiomac.2020.08.235   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 He P, Mann-Collura O, Fling J, Edara N, Hetz R, Razzaque MS. High phosphate actively induces cytotoxicity by rewiring pro-survival and pro-apoptotic signaling networks in HEK293 and HeLa cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32892444 DOI: 10.1096/fj.202000799RR   
2020 Wu W, Stork B. The phospho-barcode of RIPK1: complementarity or redundancy? Molecular & Cellular Oncology. 7: 1776085. PMID 32944633 DOI: 10.1080/23723556.2020.1776085   
2020 Iannuzzi CA, Indovina P, Forte IM, Di Somma S, Malfitano AM, Bruno M, Portella G, Pentimalli F, Giordano A. Pharmacological Inhibition of WEE1 Potentiates the Antitumoral Effect of the Oncolytic Virus in Malignant Mesothelioma Cell Lines. International Journal of Molecular Sciences. 21. PMID 33020398 DOI: 10.3390/ijms21197333   
2020 Park J, Woo YK, Cho HJ. Regulation of Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Activity of Advanced Cooling Composition (ACC) in UVB-Irradiated Human HaCaT Keratinocytes. International Journal of Molecular Sciences. 21. PMID 32906658 DOI: 10.3390/ijms21186527   
2020 Liao S, Feng W, Liu Y, Wang Z, Ding X, Song F, Lin X, Song H, Kc A, Su Y, Liang J, Xu J, Liu Q, Zhao J. Inhibitory effects of biochanin A on titanium particle-induced osteoclast activation and inflammatory bone resorption via NF-κB and MAPK pathways. Journal of Cellular Physiology. PMID 32853427 DOI: 10.1002/jcp.29948   
2020 Ren T, Tang YJ, Wang MF, Wang HS, Liu Y, Qian X, Chang C, Chen MW. Triptolide induces apoptosis through the calcium/calmodulin‑dependent protein kinase kinaseβ/AMP‑activated protein kinase signaling pathway in non‑small cell lung cancer cells. Oncology Reports. 44: 2288-2296. PMID 33000264 DOI: 10.3892/or.2020.7763   
2020 Seo SH, Kim SG, Shin JH, Ham DW, Shin EH. GRA16 Inhibits NF-κB Activation through PP2A-B55 Upregulation in Non-Small-Cell Lung Carcinoma Cells. International Journal of Molecular Sciences. 21. PMID 32927892 DOI: 10.3390/ijms21186642   
2020 Alvandi Z, Al-Mansoori LJR, Opas M. Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells. Stem Cell Research. 48: 101972. PMID 32916637 DOI: 10.1016/j.scr.2020.101972   
2020 Liu E, Shi S, Li J, Ge R, Liang T, Li Q. Farrerol maintains the contractile phenotype of VSMCs via inactivating the extracellular signal-regulated protein kinase 1/2 and p38 mitogen-activated protein kinase signaling. Molecular and Cellular Biochemistry. PMID 32840737 DOI: 10.1007/s11010-020-03878-5   
2020 Yang X, Wu D, Yuan S. Tyrosine Kinase Inhibitors in the Combination Therapy of HER2 Positive Breast Cancer. Technology in Cancer Research & Treatment. 19: 1533033820962140. PMID 33034269 DOI: 10.1177/1533033820962140   
2020 Na N, Zhao D, Zhang J, Wu J, Miao B, Li H, Luo Y, Tang Z, Zhang W, Bellanti JA, Zheng SG. Carbamylated erythropoietin regulates immune responses and promotes long-term kidney allograft survival through activation of PI3K/AKT signaling. Signal Transduction and Targeted Therapy. 5: 194. PMID 32934199 DOI: 10.1038/s41392-020-00232-5   
2020 Lin YY, Sun D, Wu YL. Novel regulation of PKC-induced inflammation by Akt and protein phosphatase 2A in ovarian granulosa cells. The Chinese Journal of Physiology. 63: 179-186. PMID 32859885 DOI: 10.4103/CJP.CJP_44_20   
2020 Miyazaki S, Kuno Y, Hayai S, Teramachi R, Yamashita R, Saito Y, Higuchi K, Nara Y, Ikeda T. An EGFR T790M-mutated lung adenocarcinoma undergoing large-cell neuroendocrine carcinoma transformation after osimertinib therapy: a case report. Journal of Medical Case Reports. 14: 122. PMID 32762742 DOI: 10.1186/s13256-020-02447-0   
2020 Amraei R, Alwani T, Ho RX, Aryan Z, Wang S, Rahimi N. Cell adhesion molecule IGPR-1 activates AMPK connecting cell adhesion to autophagy. The Journal of Biological Chemistry. PMID 32978258 DOI: 10.1074/jbc.RA120.014790   
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Manolache A, Selescu T, Maier GL, Mentel M, Ionescu AE, Neacsu C, Babes A, Szedlacsek SE. Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation. Journal of Cellular Physiology. 235: 5192-5203. PMID 31729029 DOI: 10.1002/jcp.29397   
2020 Jiao Y, Li J, Zhu S, Ahmed JZ, Li M, Shi D, Huang B. PI3K inhibitor reduces in vitro maturation and developmental competence of porcine oocytes. Theriogenology. 157: 432-439. PMID 32877843 DOI: 10.1016/j.theriogenology.2020.08.019   
2020 Gonzalez-Magaldi M, McCabe JM, Cartwright HN, Sun N, Leahy DJ. Conserved Roles for Receptor Tyrosine Kinase Extracellular Regions in Regulating Receptor and Pathway Activity. The Biochemical Journal. PMID 33043983 DOI: 10.1042/BCJ20200702   
2020 Das A, Alshareef M, Porto GBF, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment. Journal of the Neurological Sciences. 418: 117102. PMID 32866816 DOI: 10.1016/j.jns.2020.117102   
2020 Xie X, Wang X, Wu S, Yang H, Liu J, Chen H, Ding Y, Ling L, Lin H. Fatal toxic effects related to EGFR tyrosine kinase inhibitors based on 53 cohorts with 9,569 participants. Journal of Thoracic Disease. 12: 4057-4069. PMID 32944317 DOI: 10.21037/jtd-19-4000A   
2020 Xie X, Wang X, Wu S, Yang H, Liu J, Chen H, Ding Y, Ling L, Lin H. Fatal toxic effects related to EGFR tyrosine kinase inhibitors based on 53 cohorts with 9,569 participants. Journal of Thoracic Disease. 12: 4057-4069. PMID 32944317 DOI: 10.21037/jtd-19-4000A   
2020 Kwak AW, Lee MH, Yoon G, Cho SS, Choi JS, Chae JI, Shim JH. Deoxypodophyllotoxin, a Lignan from , Induces Apoptosis and Cell Cycle Arrest by Inhibiting the EGFR Signaling Pathways in Esophageal Squamous Cell Carcinoma Cells. International Journal of Molecular Sciences. 21. PMID 32961992 DOI: 10.3390/ijms21186854   
2020 Elie J, Feizbakhsh O, Desban N, Josselin B, Baratte B, Bescond A, Duez J, Fant X, Bach S, Marie D, Place M, Ben Salah S, Chartier A, Berteina-Raboin S, Chaikuad A, et al. Design of new disubstituted imidazo[1,2-]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1840-1853. PMID 33040634 DOI: 10.1080/14756366.2020.1825408   
2020 Asih PR, Prikas E, Stefanoska K, Tan ARP, Ahel HI, Ittner A. Functions of p38 MAP Kinases in the Central Nervous System. Frontiers in Molecular Neuroscience. 13: 570586. PMID 33013322 DOI: 10.3389/fnmol.2020.570586   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Tiwari A, Iida M, Kosnopfel C, Abbariki M, Menegakis A, Fehrenbacher B, Maier J, Schaller M, Brucker SY, Wheeler DL, Harari PM, Rothbauer U, Schittek B, Zips D, Toulany M. Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers. Cancers. 12. PMID 33003386 DOI: 10.3390/cancers12102795   
2020 Ren Y, Song X, Tan L, Guo C, Wang M, Liu H, Cao Z, Li Y, Peng C. A Review of the Pharmacological Properties of Psoralen. Frontiers in Pharmacology. 11: 571535. PMID 33013413 DOI: 10.3389/fphar.2020.571535   
2020 Rabani R, Cossette C, Graham F, Powell WS. Protein kinase C activates NAD kinase in human neutrophils. Free Radical Biology & Medicine. PMID 33011272 DOI: 10.1016/j.freeradbiomed.2020.09.022   
2020 Seiffert P, Bugge K, Nygaard M, Haxholm GW, Martinsen JH, Pedersen MN, Arleth L, Boomsma W, Kragelund BB. Orchestration of signaling by structural disorder in class 1 cytokine receptors. Cell Communication and Signaling : Ccs. 18: 132. PMID 32831102 DOI: 10.1186/s12964-020-00626-6