George Mackie - Publications

Affiliations: 
University of Victoria, Victoria, British Columbia, Canada 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ifill G, Blimkie T, Lee AH, Mackie GA, Chen Q, Stibitz S, Hancock REW, Fernandez RC. RNase III and RNase E Influence Posttranscriptional Regulatory Networks Involved in Virulence Factor Production, Metabolism, and Regulatory RNA Processing in Bordetella pertussis. Msphere. e0065021. PMID 34406853 DOI: 10.1128/mSphere.00650-21  0.31
2013 Mackie GA. RNase E: at the interface of bacterial RNA processing and decay. Nature Reviews. Microbiology. 11: 45-57. PMID 23241849 DOI: 10.1038/nrmicro2930  0.302
2010 Hankins JS, Denroche H, Mackie GA. Interactions of the RNA-binding protein Hfq with cspA mRNA, encoding the major cold shock protein Journal of Bacteriology. 192: 2482-2490. PMID 20233932 DOI: 10.1128/JB.01619-09  0.317
2008 Mackie GA, Coburn GA, Miao X, Briant DJ, Prud'homme-Généreux A, Stickney LM, Hankins JS. Chapter 11 Preparation of the Escherichia coli RNase E Protein and Reconstitution of the RNA Degradosome Methods in Enzymology. 447: 199-213. PMID 19161845 DOI: 10.1016/S0076-6879(08)02211-8  0.341
2004 Prud'homme-Généreux A, Beran RK, Iost I, Ramey CS, Mackie GA, Simons RW. Physical and functional interactions among RNase E, polynucleotide phosphorylase and the cold-shock protein, CsdA: evidence for a 'cold shock degradosome'. Molecular Microbiology. 54: 1409-21. PMID 15554978 DOI: 10.1111/j.1365-2958.2004.04360.x  0.317
2002 Mackie GA, Coburn GA, Miao X, Briant DJ, Prud'homme-Genereux A. Preparation of Escherichia coli Rne protein and reconstitution of RNA degradosome. Methods in Enzymology. 342: 346-56. PMID 11586907 DOI: 10.1016/S0076-6879(01)42557-2  0.321
2001 Spickler C, Stronge V, Mackie GA. Preferential cleavage of degradative intermediates of rpsT mRNA by the Escherichia coli RNA degradosome. Journal of Bacteriology. 183: 1106-9. PMID 11208812 DOI: 10.1128/JB.183.3.1106-1109.2001  0.337
1999 Coburn GA, Miao X, Briant DJ, Mackie GA. Reconstitution of a minimal RNA degradosome demonstrates functional coordination between a 3' exonuclease and a DEAD-box RNA helicase. Genes & Development. 13: 2594-603. PMID 10521403 DOI: 10.1101/GAD.13.19.2594  0.345
1999 Coburn GA, Mackie GA. Degradation of mRNA in Escherichia coli: an old problem with some new twists. Progress in Nucleic Acid Research and Molecular Biology. 62: 55-108. PMID 9932452 DOI: 10.1016/S0079-6603(08)60505-X  0.322
1998 Mackie GA. Ribonuclease E is a 5'-end-dependent endonuclease. Nature. 395: 720-3. PMID 9790196 DOI: 10.1038/27246  0.353
1998 Coburn GA, Mackie GA. Reconstitution of the degradation of the mRNA for ribosomal protein S20 with purified enzymes. Journal of Molecular Biology. 279: 1061-74. PMID 9642084 DOI: 10.1006/JMBI.1998.1842  0.371
1997 Mackie GA, Genereaux JL, Masterman SK. Modulation of the Activity of RNase E in Vitro by RNA Sequences and Secondary Structures 5′ to Cleavage Sites Journal of Biological Chemistry. 272: 609-616. DOI: 10.1074/JBC.272.1.609  0.302
1996 Coburn GA, Mackie GA. Differential sensitivities of portions of the mRNA for ribosomal protein S20 to 3'-exonucleases dependent on oligoadenylation and RNA secondary structure. The Journal of Biological Chemistry. 271: 15776-81. PMID 8663115 DOI: 10.1074/JBC.271.26.15776  0.303
1994 Mackie GA, Genereaux JL. The role of RNA structure in determining RNase E-dependent cleavage sites in the mRNA for ribosomal protein S20 in vitro. Journal of Molecular Biology. 234: 998-1012. PMID 7505337 DOI: 10.1006/JMBI.1993.1654  0.318
1993 Cormack RS, Genereaux JL, Mackie GA. RNase E activity is conferred by a single polypeptide: overexpression, purification, and properties of the ams/rne/hmp1 gene product. Proceedings of the National Academy of Sciences of the United States of America. 90: 9006-10. PMID 8415644 DOI: 10.1073/PNAS.90.19.9006  0.346
1993 Cormack RS, Mackie GA. Structural requirements for the processing of Escherichia coli 5 S ribosomal RNA by RNase E in vitro. Journal of Molecular Biology. 228: 1078-90. PMID 1474579 DOI: 10.1016/0022-2836(92)90316-C  0.361
1992 White KA, Bancroft JB, Mackie GA. Mutagenesis of a hexanucleotide sequence conserved in potexvirus RNAs. Virology. 189: 817-20. PMID 1641994 DOI: 10.1016/0042-6822(92)90614-U  0.301
1991 Mackie GA. Specific endonucleolytic cleavage of the mRNA for ribosomal protein S20 of Escherichia coli requires the product of the ams gene in vivo and in vitro. Journal of Bacteriology. 173: 2488-97. PMID 2013571 DOI: 10.1128/jb.173.8.2488-2497.1991  0.347
1991 White KA, Bancroft JB, Mackie GA. Defective RNAs of clover yellow mosaic virus encode nonstructural/coat protein fusion products. Virology. 183: 479-86. PMID 1830181 DOI: 10.1016/0042-6822(91)90977-J  0.327
1990 White KA, Mackie GA. Control and expression of 3′ open reading frames in clover yellow mosaic virus Virology. 179: 576-584. PMID 2238463 DOI: 10.1016/0042-6822(90)90124-A  0.312
1978 Mackie GA, Zimmermann RA. RNA--protein interactions in the ribosome. IV. Structure and properties of binding sites for proteins S4, S16/S17 and S20 in the 16S RNA. Journal of Molecular Biology. 121: 17-39. PMID 660650 DOI: 10.1016/0022-2836(78)90260-7  0.314
1977 Geisser M, Mackie GA. The binding site of Escherichia coli ribosomal protein S4 on 16-S ribosomal RNA from different bacterial species. European Journal of Biochemistry. 70: 159-70. PMID 827436 DOI: 10.1111/J.1432-1033.1976.TB10966.X  0.364
1975 Zimmermann RA, Mackie GA, Muto A, Garrett RA, Ungewickell E, Ehresmann C, Stiegler P, Ebel JP, Fellner P. Location and characteristics of ribosomal protein binding sites in the 16S RNA of Escherichia coli. Nucleic Acids Research. 2: 279-302. PMID 1091919 DOI: 10.1093/nar/2.2.279  0.316
1974 Zimmermann RA, Muto A, Mackie GA. RNA-protein interactions in the ribosome. II. Binding of ribosomal proteins to isolated fragments of the 16 S RNA. Journal of Molecular Biology. 86: 433-50. PMID 4607041 DOI: 10.1016/0022-2836(74)90029-1  0.32
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