Cristiana Cruceanu - Publications

Affiliations: 
Human Genetics McGill University, Montreal, QC, Canada 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry J, Backlund L, Bhattacharjee AK, Bellivier F, ... ... Cruceanu C, et al. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM. The British Journal of Psychiatry : the Journal of Mental Science. 1. PMID 35505515 DOI: 10.1192/bjp.2022.55  0.654
2022 Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, ... ... Cruceanu C, et al. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach. The British Journal of Psychiatry : the Journal of Mental Science. 1-10. PMID 35225756 DOI: 10.1192/bjp.2022.28  0.681
2021 Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, ... ... Cruceanu C, et al. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry : the Journal of Mental Science. 219: 659-669. PMID 35048876 DOI: 10.1192/bjp.2021.102  0.677
2021 Lin R, Lopez JP, Cruceanu C, Pierotti C, Fiori LM, Squassina A, Chillotti C, Dieterich C, Mellios N, Turecki G. Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder. Translational Psychiatry. 11: 629. PMID 34893581 DOI: 10.1038/s41398-021-01746-4  0.813
2021 Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, ... ... Cruceanu C, et al. Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry. 11: 606. PMID 34845190 DOI: 10.1038/s41398-021-01702-2  0.717
2021 Le Clerc S, Lombardi L, Baune BT, Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, ... ... Cruceanu C, et al. HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders. Scientific Reports. 11: 17823. PMID 34497278 DOI: 10.1038/s41598-021-97140-7  0.667
2021 Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, ... ... Cruceanu C, et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics. PMID 34002096 DOI: 10.1038/s41588-021-00857-4  0.748
2021 Stone W, Nunes A, Akiyama K, Akula N, Ardau R, Aubry JM, Backlund L, Bauer M, Bellivier F, Cervantes P, Chen HC, Chillotti C, Cruceanu C, Dayer A, Degenhardt F, et al. Prediction of lithium response using genomic data. Scientific Reports. 11: 1155. PMID 33441847 DOI: 10.1038/s41598-020-80814-z  0.547
2021 Pisanu C, Congiu D, Severino G, Niola P, Lopez JP, Cruceanu C, Ardau R, Papadima EM, Loizedda A, Orrù N, Calza S, Orrù S, Carcassi C, Alda M, Chillotti C, et al. Involvement of microRNAs in Lithium Response in Patients With Bipolar Disorder and Related Phenotypes Biological Psychiatry. 89: S13. DOI: 10.1016/j.biopsych.2021.02.053  0.411
2020 Squassina A, Niola P, Lopez JP, Cruceanu C, Pisanu C, Congiu D, Severino G, Ardau R, Chillotti C, Alda M, Turecki G, Del Zompo M. MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 32241689 DOI: 10.1016/J.Euroneuro.2020.03.005  0.727
2020 Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, ... ... Cruceanu C, et al. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry. PMID 32203155 DOI: 10.1038/S41380-020-0689-5  0.725
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Cruceanu C, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.752
2018 Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M, Anderson-Schmidt H, Andlauer TF, Anghelescu IG, Ardau R, Arias B, ... ... Cruceanu C, et al. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study. Bipolar Disorders. PMID 29956436 DOI: 10.1111/Bdi.12659  0.685
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Cruceanu C, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.717
2018 Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, ... ... Cruceanu C, et al. Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder. Frontiers in Psychiatry. 9: 207. PMID 29904359 DOI: 10.3389/Fpsyt.2018.00207  0.687
2018 Matosin N, Martinelli S, Cruceanu C, Turecki G, Binder E. 69. The Postmortem Human Brain to Characterize Novel Drug Targets for Psychiatric Disorders: Using FKBP5 as an Example Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.086  0.492
2017 Mühleisen TW, Reinbold CS, Forstner AJ, Abramova LI, Alda M, Babadjanova G, Bauer M, Brennan P, Chuchalin A, Cruceanu C, Czerski PM, Degenhardt F, Fischer SB, Fullerton JM, Gordon SD, et al. Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. Journal of Affective Disorders. 228: 20-25. PMID 29197740 DOI: 10.1016/J.Jad.2017.11.068  0.768
2017 Cruceanu C, Schmouth JF, Torres-Platas SG, Lopez JP, Ambalavanan A, Darcq E, Gross F, Breton B, Spiegelman D, Rochefort D, Hince P, Petite JM, Gauthier J, Lafrenière RG, Dion PA, et al. Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors. Molecular Psychiatry. PMID 29158579 DOI: 10.1038/mp.2017.223  0.689
2017 Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, ... ... Cruceanu C, et al. Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. Jama Psychiatry. PMID 29121268 DOI: 10.1001/Jamapsychiatry.2017.3433  0.715
2017 Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, ... ... Cruceanu C, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Translational Psychiatry. 7: e1155. PMID 28632202 DOI: 10.1038/Tp.2017.115  0.721
2017 Papadima EM, Niola P, Melis C, Pisanu C, Congiu D, Cruceanu C, Lopez JP, Turecki G, Ardau R, Severino G, Chillotti C, Del Zompo M, Squassina A. Evidence towards RNA Binding Motif (RNP1, RRM) Protein 3 (RBM3) as a Potential Biomarker of Lithium Response in Bipolar Disorder Patients. Journal of Molecular Neuroscience : Mn. PMID 28616776 DOI: 10.1007/S12031-017-0938-5  0.747
2017 Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, et al. MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications. 8: 15497. PMID 28530238 DOI: 10.1038/Ncomms15497  0.771
2017 Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, Leber M, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Streit F, Meier S, Herms S, ... ... Cruceanu C, et al. Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. Plos One. 12: e0171595. PMID 28166306 DOI: 10.1371/Journal.Pone.0171595  0.724
2017 Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O'Dushlaine C, et al. Cover Image, Volume 173A, Number 2, February 2017. American Journal of Medical Genetics. Part A. 173: i. PMID 28102589 DOI: 10.1002/ajmg.a.37896  0.756
2016 Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O'Dushlaine C, et al. Implication of LRRC4C and DPP6 in neurodevelopmental disorders. American Journal of Medical Genetics. Part A. PMID 27759917 DOI: 10.1002/Ajmg.A.38021  0.799
2016 Cruceanu C, Kutsarova E, Chen ES, Checknita DR, Nagy C, Lopez JP, Alda M, Rouleau GA, Turecki G. DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression. Bmc Psychiatry. 16: 286. PMID 27515700 DOI: 10.1186/S12888-016-0989-0  0.817
2016 Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, ... ... Cruceanu C, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Human Molecular Genetics. PMID 27329760 DOI: 10.1093/Hmg/Ddw181  0.71
2016 Squassina A, Pisanu C, Congiu D, Caria P, Frau D, Niola P, Melis C, Baggiani G, Lopez JP, Cruceanu C, Turecki G, Severino G, Bocchetta A, Vanni R, Chillotti C, et al. Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27084304 DOI: 10.1016/J.Euroneuro.2016.03.020  0.694
2016 Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CE, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, ... ... Cruceanu C, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet (London, England). PMID 26806518 DOI: 10.1016/S0140-6736(16)00143-4  0.706
2015 Forstner AJ, Hofmann A, Maaser A, Sumer S, Khudayberdiev S, Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Breuer R, Meier S, ... ... Cruceanu C, et al. Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Translational Psychiatry. 5: e678. PMID 26556287 DOI: 10.1038/Tp.2015.159  0.714
2015 Cruceanu C, Tan PP, Rogic S, Lopez JP, Torres-Platas SG, Gigek CO, Alda M, Rouleau GA, Pavlidis P, Turecki G. Transcriptome Sequencing of the Anterior Cingulate in Bipolar Disorder: Dysregulation of G Protein-Coupled Receptors. The American Journal of Psychiatry. appiajp201514101279. PMID 26238605 DOI: 10.1176/Appi.Ajp.2015.14101279  0.813
2015 Lopez JP, Diallo A, Cruceanu C, Fiori LM, Laboissiere S, Guillet I, Fontaine J, Ragoussis J, Benes V, Turecki G, Ernst C. Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing. Bmc Medical Genomics. 8: 35. PMID 26130076 DOI: 10.1186/S12920-015-0109-X  0.772
2015 Nagy C, Maheu M, Lopez JP, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G. Effects of postmortem interval on biomolecule integrity in the brain. Journal of Neuropathology and Experimental Neurology. 74: 459-69. PMID 25868148 DOI: 10.1097/Nen.0000000000000190  0.768
2015 Hunsberger JG, Chibane FL, Elkahloun AG, Henderson R, Singh R, Lawson J, Cruceanu C, Nagarajan V, Turecki G, Squassina A, Medeiros CD, Del Zompo M, Rouleau GA, Alda M, Chuang DM. Novel integrative genomic tool for interrogating lithium response in bipolar disorder. Translational Psychiatry. 5: e504. PMID 25646593 DOI: 10.1038/Tp.2014.139  0.711
2015 Cruceanu C, Alda M, Dion PA, Turecki G, Rouleau GA. No evidence for GADL1 variation as a bipolar disorder susceptibility factor in a Caucasian lithium-responsive cohort. The American Journal of Psychiatry. 172: 94-5. PMID 25553497 DOI: 10.1176/Appi.Ajp.2014.14070855  0.73
2015 Lopez JP, Diallo A, Cruceanu C, Fiori LM, Laboissiere S, Guillet I, Fontaine J, Ragoussis J, Benes V, Turecki G, Ernst C. Biomarker discovery: Quantification of microRNAs and other small non-coding RNAs using next generation sequencing Bmc Medical Genomics. 8. DOI: 10.1186/s12920-015-0109-x  0.701
2014 Lopez JP, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E, El Mestikawy S, Mechawar N, Pavlidis P, Turecki G. miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. Nature Medicine. 20: 764-8. PMID 24908571 DOI: 10.1038/Nm.3582  0.788
2014 Torres-Platas SG, Cruceanu C, Chen GG, Turecki G, Mechawar N. Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides. Brain, Behavior, and Immunity. 42: 50-9. PMID 24858659 DOI: 10.1016/J.Bbi.2014.05.007  0.42
2014 Torres-Platas SG, Comeau S, Rachalski A, Bo GD, Cruceanu C, Turecki G, Giros B, Mechawar N. Morphometric characterization of microglial phenotypes in human cerebral cortex. Journal of Neuroinflammation. 11: 12. PMID 24447857 DOI: 10.1186/1742-2094-11-12  0.461
2014 Huzayyin AA, Andreazza AC, Turecki G, Cruceanu C, Rouleau GA, Alda M, Young LT. Decreased global methylation in patients with bipolar disorder who respond to lithium. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 561-9. PMID 24345589 DOI: 10.1017/S1461145713001569  0.654
2013 Cruceanu C, Ambalavanan A, Spiegelman D, Gauthier J, Lafrenière RG, Dion PA, Alda M, Turecki G, Rouleau GA. Family-based exome-sequencing approach identifies rare susceptibility variants for lithium-responsive bipolar disorder. Genome / National Research Council Canada = Gã©Nome / Conseil National De Recherches Canada. 56: 634-40. PMID 24237345 DOI: 10.1139/gen-2013-0081  0.701
2013 Freemantle E, Chen GG, Cruceanu C, Mechawar N, Turecki G. Analysis of oxysterols and cholesterol in prefrontal cortex of suicides. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1241-9. PMID 23369504 DOI: 10.1017/S1461145712001587  0.783
2013 Cruceanu C, Freemantle E, Alda M, Rouleau GA, Turecki G. Epigenetic regulation of synapsin genes in mood disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 239-41. PMID 23147482 DOI: 10.1038/Npp.2012.186  0.805
2013 Cruceanu C, Alda M, Nagy C, Freemantle E, Rouleau GA, Turecki G. H3K4 tri-methylation in synapsin genes leads to different expression patterns in bipolar disorder and major depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 289-99. PMID 22571925 DOI: 10.1017/S1461145712000363  0.812
2012 Cruceanu C, Alda M, Grof P, Rouleau GA, Turecki G. Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder. Plos One. 7: e32680. PMID 22384280 DOI: 10.1371/Journal.Pone.0032680  0.714
2011 Cruceanu C, Alda M, Rouleau G, Turecki G. Response to treatment in bipolar disorder. Current Opinion in Psychiatry. 24: 24-8. PMID 21088584 DOI: 10.1097/Yco.0B013E328341352C  0.743
2010 Lopez de Lara C, Jaitovich-Groisman I, Cruceanu C, Mamdani F, Lebel V, Yerko V, Beck A, Young LT, Rouleau G, Grof P, Alda M, Turecki G. Implication of synapse-related genes in bipolar disorder by linkage and gene expression analyses. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1397-410. PMID 20667171 DOI: 10.1017/S1461145710000714  0.806
2009 Cruceanu C, Alda M, Turecki G. Lithium: a key to the genetics of bipolar disorder. Genome Medicine. 1: 79. PMID 19691823 DOI: 10.1186/Gm79  0.709
2008 Cruceanu C, de Lara CL, Alda M, Turecki G. Pharmacogenetics of Lithium Response Psychiatric Annals. 38: 401-407. DOI: 10.3928/00485713-20080601-09  0.575
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