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Adolfo Sequeira, Ph.D. - Publications

Affiliations: 
2000-2006 Human Genetics McGill University, Montreal, QC, Canada 
 2007- Psychiatry and Human Behavior University of California Irvine School of Medicine, Irvine, CA, United States 
Area:
Genetics, Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Neuromodulation, Psychiatry, Telomeres
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Moyers BA, Loupe JM, Felker SA, Lawlor JMJ, Anderson AG, Rodriguez-Nunez I, Bunney WE, Bunney BG, Cartagena PM, Sequeira A, Watson SJ, Akil H, Mendenhall EM, Cooper GM, Myers RM. Allele biased transcription factor binding across human brain regions gives mechanistic insight into eQTLs. Biorxiv : the Preprint Server For Biology. PMID 37873117 DOI: 10.1101/2023.10.06.561245  0.483
2022 Hjelm BE, Ramiro C, Rollins BL, Omidsalar AA, Gerke DS, Das SC, Sequeira A, Morgan L, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, et al. Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3' Breakpoints. Complex Psychiatry. 8: 90-98. PMID 36778651 DOI: 10.1159/000528051  0.437
2022 Das SC, Hjelm BE, Rollins BL, Sequeira A, Morgan L, Omidsalar AA, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder. Translational Psychiatry. 12: 353. PMID 36042222 DOI: 10.1038/s41398-022-02127-1  0.476
2022 Mamdani F, Sequeira A. Blood-based biomarkers for suicide in depression: moving a step closer to prediction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35882924 DOI: 10.1038/s41386-022-01391-5  0.747
2022 Mamdani F, Weber MD, Bunney B, Burke K, Cartagena P, Walsh D, Lee FS, Barchas J, Schatzberg AF, Myers RM, Watson SJ, Akil H, Vawter MP, Bunney WE, Sequeira A. Identification of potential blood biomarkers associated with suicide in major depressive disorder. Translational Psychiatry. 12: 159. PMID 35422091 DOI: 10.1038/s41398-022-01918-w  0.811
2020 Scaduto P, Sequeira A, Vawter MP, Bunney W, Limon A. Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals. Scientific Reports. 10: 8626. PMID 32451470 DOI: 10.1038/S41598-020-65377-3  0.475
2019 Limon A, Delbruck E, Yassine A, Pandya D, Myers RM, Barchas JD, Lee F, Schatzberg, Watson SJ, Akil H, Bunney WE, Vawter MP, Sequeira A. Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA receptors. Translational Psychiatry. 9: 218. PMID 31488811 DOI: 10.1038/S41398-019-0551-1  0.532
2019 Hjelm BE, Rollins B, Morgan L, Sequeira A, Mamdani F, Pereira F, Damas J, Webb MG, Weber MD, Schatzberg AF, Barchas JD, Lee FS, Akil H, Watson SJ, Myers RM, et al. Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders. Nucleic Acids Research. PMID 30869147 DOI: 10.1093/Nar/Gkz164  0.758
2019 Le-Niculescu H, Roseberry K, Levey DF, Rogers J, Kosary K, Prabha S, Jones T, Judd S, McCormick MA, Wessel AR, Williams A, Phalen PL, Mamdani F, Sequeira A, Kurian SM, et al. Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs. Molecular Psychiatry. PMID 30862937 DOI: 10.1038/S41380-019-0370-Z  0.735
2018 Gonçalves VF, Cappi C, Hagen CM, Sequeira A, Vawter MP, Derkach A, Zai CC, Hedley PL, Bybjerg-Grauholm J, Pouget JG, Cuperfain AB, Sullivan PF, Christiansen M, Kennedy JL, Sun L. A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia. Biological Psychiatry. 83: 780-789. PMID 29628042 DOI: 10.1016/j.biopsych.2018.02.1175  0.388
2018 Rollins BL, Morgan L, Hjelm BE, Sequeira A, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP. Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence. Molecular Neuropsychiatry. 3: 157-169. PMID 29594135 DOI: 10.1159/000484348  0.466
2016 Limon A, Mamdani F, Hjelm BE, Vawter MP, Sequeira A. Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission. Neuroscience and Biobehavioral Reviews. PMID 27108532 DOI: 10.1016/J.Neubiorev.2016.04.010  0.752
2016 Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders. Microarrays (Basel, Switzerland). 5. PMID 26998349 DOI: 10.3390/Microarrays5010006  0.579
2015 Hjelm BE, Rollins B, Mamdani F, Lauterborn JC, Kirov G, Lynch G, Gall CM, Sequeira A, Vawter MP. Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia. Molecular Neuropsychiatry. 1: 201-219. PMID 26550561 DOI: 10.1159/000441252  0.712
2015 Sequeira A, Rollins B, Magnan C, van Oven M, Baldi P, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Vawter MP. Mitochondrial mutations in subjects with psychiatric disorders. Plos One. 10: e0127280. PMID 26011537 DOI: 10.1371/Journal.Pone.0127280  0.576
2014 Esmailpour T, Riazifar H, Liu L, Donkervoort S, Huang VH, Madaan S, Shoucri BM, Busch A, Wu J, Towbin A, Chadwick RB, Sequeira A, Vawter MP, Sun G, Johnston JJ, et al. A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome. Journal of Medical Genetics. 51: 185-96. PMID 24431331 DOI: 10.1136/Jmedgenet-2013-101660  0.315
2014 Guella I, Sequeira A, Rollins B, Morgan L, Myers RM, Watson SJ, Akil H, Bunney WE, Delisi LE, Byerley W, Vawter MP. Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex. Schizophrenia Research. 152: 111-6. PMID 24315717 DOI: 10.1016/J.Schres.2013.11.021  0.52
2013 Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, et al. Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11839-51. PMID 23864674 DOI: 10.1523/Jneurosci.1252-13.2013  0.537
2013 Guella I, Sequeira A, Rollins B, Morgan L, Torri F, van Erp TG, Myers RM, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Bunney WE, Potkin SG, Macciardi F, Vawter MP. Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. Journal of Psychiatric Research. 47: 1215-21. PMID 23786914 DOI: 10.1016/J.Jpsychires.2013.05.021  0.516
2012 Sequeira A, Martin MV, Rollins B, Moon EA, Bunney WE, Macciardi F, Lupoli S, Smith EN, Kelsoe J, Magnan CN, van Oven M, Baldi P, Wallace DC, Vawter MP. Mitochondrial mutations and polymorphisms in psychiatric disorders. Frontiers in Genetics. 3: 103. PMID 22723804 DOI: 10.3389/Fgene.2012.00103  0.58
2012 Sequeira A, Morgan L, Walsh DM, Cartagena PM, Choudary P, Li J, Schatzberg AF, Watson SJ, Akil H, Myers RM, Jones EG, Bunney WE, Vawter MP. Gene expression changes in the prefrontal cortex, anterior cingulate cortex and nucleus accumbens of mood disorders subjects that committed suicide. Plos One. 7: e35367. PMID 22558144 DOI: 10.1371/Journal.Pone.0035367  0.675
2011 Moon E, Rollins B, Mesén A, Sequeira A, Myers RM, Akil H, Watson SJ, Barchas J, Jones EG, Schatzberg A, Bunney WE, DeLisi LE, Byerley W, Vawter MP. Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population. Schizophrenia Research. 131: 52-7. PMID 21745728 DOI: 10.1016/J.Schres.2011.06.024  0.578
2010 Lalovic A, Klempan T, Sequeira A, Luheshi G, Turecki G. Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers. Journal of Affective Disorders. 120: 24-31. PMID 19443042 DOI: 10.1016/J.Jad.2009.04.007  0.825
2009 Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. Plos One. 4: e6585. PMID 19668376 DOI: 10.1371/Journal.Pone.0006585  0.814
2009 Klempan TA, Rujescu D, Mérette C, Himmelman C, Sequeira A, Canetti L, Fiori LM, Schneider B, Bureau A, Turecki G. Profiling brain expression of the spermidine/spermine N1-acetyltransferase 1 (SAT1) gene in suicide. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 934-43. PMID 19152344 DOI: 10.1002/Ajmg.B.30920  0.778
2009 Ernst C, Deleva V, Deng X, Sequeira A, Pomarenski A, Klempan T, Ernst N, Quirion R, Gratton A, Szyf M, Turecki G. Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Archives of General Psychiatry. 66: 22-32. PMID 19124685 DOI: 10.1001/Archpsyc.66.1.22  0.667
2009 Klempan TA, Sequeira A, Canetti L, Lalovic A, Ernst C, ffrench-Mullen J, Turecki G. Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression. Molecular Psychiatry. 14: 175-89. PMID 17938633 DOI: 10.1038/Sj.Mp.4002110  0.814
2008 Sequeira A, Meng F, Rollins B, Myers RM, Jones EG, Watson SJ, Akil H, Schatzberg AF, Barchas J, Bunney WE, Vawter MP. Coding SNPs included in exon arrays for the study of psychiatric disorders. Molecular Psychiatry. 13: 363-5. PMID 18347597 DOI: 10.1038/Sj.Mp.4002123  0.579
2007 Lalovic A, Levy E, Canetti L, Sequeira A, Montoudis A, Turecki G. Fatty acid composition in postmortem brains of people who completed suicide. Journal of Psychiatry & Neuroscience : Jpn. 32: 363-70. PMID 17823652  0.788
2007 Ernst C, Sequeira A, Klempan T, Ernst N, Ffrench-Mullen J, Turecki G. Confirmation of region-specific patterns of gene expression in the human brain. Neurogenetics. 8: 219-24. PMID 17375343 DOI: 10.1007/S10048-007-0084-2  0.614
2007 Sequeira A, Klempan T, Canetti L, ffrench-Mullen J, Benkelfat C, Rouleau GA, Turecki G. Patterns of gene expression in the limbic system of suicides with and without major depression. Molecular Psychiatry. 12: 640-55. PMID 17353912 DOI: 10.1038/Sj.Mp.4001969  0.709
2007 Mamdani F, Sequeira A, Alda M, Grof P, Rouleau G, Turecki G. No association between the PREP gene and lithium responsive bipolar disorder. Bmc Psychiatry. 7: 9. PMID 17324276 DOI: 10.1186/1471-244X-7-9  0.774
2007 Lalovic A, Levy E, Luheshi G, Canetti L, Grenier E, Sequeira A, Turecki G. Cholesterol content in brains of suicide completers. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 159-66. PMID 16707033 DOI: 10.1017/S1461145706006663  0.798
2006 Sequeira A, Turecki G. Genome wide gene expression studies in mood disorders. Omics : a Journal of Integrative Biology. 10: 444-54. PMID 17233556 DOI: 10.1089/Omi.2006.10.444  0.575
2006 Sequeira A, Gwadry FG, Ffrench-Mullen JM, Canetti L, Gingras Y, Casero RA, Rouleau G, Benkelfat C, Turecki G. Implication of SSAT by gene expression and genetic variation in suicide and major depression. Archives of General Psychiatry. 63: 35-48. PMID 16389195 DOI: 10.1001/Archpsyc.63.1.35  0.673
2005 Gwadry FG, Sequeira A, Hoke G, Ffrench-Mullen JM, Turecki G. Molecular characterization of suicide by microarray analysis. American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 133: 48-56. PMID 15645524 DOI: 10.1002/Ajmg.C.30046  0.625
2004 Lalovic A, Sequeira A, DeGuzman R, Chawky N, Lesage A, Seguin M, Turecki G. Investigation of completed suicide and genes involved in cholesterol metabolism. Journal of Affective Disorders. 79: 25-32. PMID 15023477 DOI: 10.1016/S0165-0327(02)00453-6  0.805
2004 Sequeira A, Mamdani F, Lalovic A, Anguelova M, Lesage A, Seguin M, Chawky N, Desautels A, Turecki G. Alpha 2A adrenergic receptor gene and suicide. Psychiatry Research. 125: 87-93. PMID 15006432 DOI: 10.1016/J.Psychres.2003.12.002  0.765
2003 Lemonde S, Turecki G, Bakish D, Du L, Hrdina PD, Bown CD, Sequeira A, Kushwaha N, Morris SJ, Basak A, Ou XM, Albert PR. Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8788-99. PMID 14507979 DOI: 10.1523/Jneurosci.23-25-08788.2003  0.56
2003 Sequeira A, Kim C, Seguin M, Lesage A, Chawky N, Desautels A, Tousignant M, Vanier C, Lipp O, Benkelfat C, Rouleau G, Turecki G. Wolfram syndrome and suicide: Evidence for a role of WFS1 in suicidal and impulsive behavior. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 119: 108-13. PMID 12707947 DOI: 10.1002/Ajmg.B.20011  0.811
2003 Turecki G, Sequeira A, Gingras Y, Séguin M, Lesage A, Tousignant M, Chawky N, Vanier C, Lipp O, Benkelfat C, Rouleau GA. Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 118: 36-40. PMID 12627464 DOI: 10.1002/Ajmg.B.10006  0.682
2002 Desautels A, Turecki G, Montplaisir J, Brisebois K, Sequeira A, Adam B, Rouleau GA. Evidence for a genetic association between monoamine oxidase A and restless legs syndrome. Neurology. 59: 215-9. PMID 12136060 DOI: 10.1212/Wnl.59.2.215  0.728
2001 Desautels A, Turecki G, Montplaisir J, Sequeira A, Verner A, Rouleau GA. Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q. American Journal of Human Genetics. 69: 1266-70. PMID 11704926 DOI: 10.1086/324649  0.691
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