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E. Antonio Chiocca, MD - Publications

Affiliations: 
2004-2012 Neurosurgery Ohio State University, Columbus, Columbus, OH 
 2012- Neurosurgery Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States 
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273 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Reddy R, Yan SC, Hasanpour Segherlou Z, Hosseini-Siyanaki MR, Poe J, Perez-Vega C, Chiocca EA, Lucke-Wold B. Oncolytic viral therapy: a review and promising future directions. Journal of Neurosurgery. 1-9. PMID 37877961 DOI: 10.3171/2023.6.JNS23243  0.325
2023 Koch MS, Zdioruk M, Nowicki MO, Hoetker MS, Herbert ZT, Barone F, Tak PP, Chiocca EA, Tabatabai G, Lawler SE. Uncovering transcriptomic landscape alterations of CAN-2409 in and glioma models. Frontiers in Medicine. 10: 1140352. PMID 37228396 DOI: 10.3389/fmed.2023.1140352  0.327
2022 Ma R, Li Z, Chiocca EA, Caligiuri MA, Yu J. The emerging field of oncolytic virus-based cancer immunotherapy. Trends in Cancer. PMID 36402738 DOI: 10.1016/j.trecan.2022.10.003  0.336
2022 Tian L, Xu B, Chen Y, Li Z, Wang J, Zhang J, Ma R, Cao S, Hu W, Chiocca EA, Kaur B, Caligiuri MA, Yu J. Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab-CCL5 fusion protein via innate and adaptive immunity. Nature Cancer. PMID 36357700 DOI: 10.1038/s43018-022-00448-0  0.569
2022 Berger G, Knelson EH, Jimenez-Macias JL, Nowicki MO, Han S, Panagioti E, Lizotte PH, Adu-Berchie K, Stafford A, Dimitrakakis N, Zhou L, Chiocca EA, Mooney DJ, Barbie DA, Lawler SE. STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models. Proceedings of the National Academy of Sciences of the United States of America. 119: e2111003119. PMID 35787058 DOI: 10.1073/pnas.2111003119  0.32
2022 Jenner AL, Smalley M, Goldman D, Goins WF, Cobbs CS, Puchalski RB, Chiocca EA, Lawler S, Macklin P, Goldman A, Craig M. Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy. Iscience. 25: 104395. PMID 35637733 DOI: 10.1016/j.isci.2022.104395  0.314
2022 Bhere D, Choi SH, van de Donk P, Hope D, Gortzak K, Kunnummal A, Khalsa J, Revai Lechtich E, Reinshagen C, Leon V, Nissar N, Bi WL, Feng C, Li H, Zhang YS, ... ... Chiocca EA, et al. Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells. Nature Communications. 13: 2810. PMID 35589724 DOI: 10.1038/s41467-022-30558-3  0.336
2022 Blitz SE, Kappel AD, Gessler FA, Klinger NV, Arnaout O, Lu Y, Peruzzi PP, Smith TR, Chiocca EA, Friedman GK, Bernstock JD. Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword. International Journal of Molecular Sciences. 23. PMID 35163730 DOI: 10.3390/ijms23031808  0.308
2022 Tian T, Liang R, Erel-Akbaba G, Saad L, Obeid PJ, Gao J, Chiocca EA, Weissleder R, Tannous BA. Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles. Acs Nano. PMID 35099172 DOI: 10.1021/acsnano.1c05505  0.304
2022 Otani Y, Yoo JY, Lewis CT, Chao S, Swanner J, Shimizu T, Kang JM, Murphy SA, Rivera-Caraballo K, Hong B, Glorioso JC, Nakashima H, Lawler SE, Banasavadi-Siddegowda Y, Heiss JD, ... ... Chiocca EA, et al. NOTCH induced MDSC recruitment after oHSV virotherapy in CNS cancer models modulates anti-tumor immunotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 35022322 DOI: 10.1158/1078-0432.CCR-21-2347  0.533
2021 Jackson JW, Hall BL, Marzulli M, Shah VK, Bailey L, Chiocca EA, Goins WF, Kohanbash G, Cohen JB, Glorioso JC. Treatment of glioblastoma with current oHSV variants reveals differences in efficacy and immune cell recruitment. Molecular Therapy Oncolytics. 22: 444-453. PMID 34553031 DOI: 10.1016/j.omto.2021.07.009  0.355
2020 Glorioso JC, Cohen JB, Goins WF, Hall B, Jackson JW, Kohanbash G, Amankulor N, Kaur B, Caligiuri MA, Chiocca EA, Holland EC, Quéva C. Oncolytic HSV Vectors and Anti-Tumor Immunity. Current Issues in Molecular Biology. 41: 381-468. PMID 32938804 DOI: 10.21775/Cimb.041.381  0.59
2020 Mineo M, Lyons SM, Zdioruk M, von Spreckelsen N, Ferrer-Luna R, Ito H, Alayo QA, Kharel P, Giantini Larsen A, Fan WY, Auduong S, Grauwet K, Passaro C, Khalsa JK, Shah K, ... ... Chiocca EA, et al. Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus. Molecular Cell. PMID 32504554 DOI: 10.1016/J.Molcel.2020.05.015  0.329
2020 Bronisz A, Salińska E, Chiocca EA, Godlewski J. Hypoxic Roadmap of Glioblastoma-Learning about Directions and Distances in the Brain Tumor Environment. Cancers. 12: 1213. PMID 32413951 DOI: 10.3390/Cancers12051213  0.413
2020 Fadzen CM, Wolfe JM, Zhou W, Cho CF, von Spreckelsen N, Hutchinson KT, Lee YC, Chiocca EA, Lawler S, Yilmaz ÖH, Lippard SJ, Pentelute BL. A Platinum(IV) Prodrug - Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain. Journal of Medicinal Chemistry. PMID 32410451 DOI: 10.1021/Acs.Jmedchem.0C00022  0.307
2020 Chiocca EA, Nakashima H, Kasai K, Fernandez SA, Oglesbee M. Preclinical Toxicology of rQNestin34.5v.2: An Oncolytic Herpes Virus with Transcriptional Regulation of the ICP34.5 Neurovirulence Gene. Molecular Therapy. Methods & Clinical Development. 17: 871-893. PMID 32373649 DOI: 10.1016/J.Omtm.2020.03.028  0.35
2020 Wen PY, Weller M, Lee EQ, Alexander BA, Barnholtz-Sloan JS, Barthel FP, Batchelor TT, Bindra RS, Chang SM, Chiocca EA, Cloughesy TF, DeGroot JF, Galanis E, Gilbert MR, Hegi ME, et al. Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions. Neuro-Oncology. PMID 32328653 DOI: 10.1093/Neuonc/Noaa106  0.361
2020 Touat M, Li YY, Boynton AN, Spurr LF, Iorgulescu JB, Bohrson CL, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ, Pal S, Ferrer-Luna R, Ramkissoon SH, Dubois F, ... ... Chiocca EA, et al. Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. 580: 517-523. PMID 32322066 DOI: 10.1038/S41586-020-2209-9  0.329
2020 Lawler SE, Chiocca EA, Cook CH. Cytomegalovirus encephalopathy during brain tumor irradiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32276942 DOI: 10.1158/1078-0432.Ccr-20-0646  0.374
2020 Spreckelsen Nv, Waldt N, Poetschke R, Kesseler C, Dohmen H, Jiao H, Nemeth A, Schob S, Scherlach C, Sandalcioglu IE, Deckert M, Angenstein F, Krischek B, Stavrinou P, Timmer M, ... ... Chiocca EA, et al. KLF4K409Q-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment. Acta Neuropathologica Communications. 8: 41. PMID 32245394 DOI: 10.1186/S40478-020-00912-X  0.337
2020 Alayo QA, Ito H, Passaro C, Zdioruk M, Mahmoud AB, Grauwet K, Zhang X, Lawler SE, Reardon DA, Goins WF, Fernandez S, Chiocca EA, Nakashima H. Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses. Scientific Reports. 10: 5095. PMID 32198420 DOI: 10.1038/S41598-020-61736-2  0.422
2020 Ricklefs FL, Maire CL, Matschke J, Dührsen L, Sauvigny T, Holz M, Kolbe K, Peine S, Herold-Mende C, Carter B, Chiocca EA, Lawler SE, Westphal M, Lamszus K. FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles. International Journal of Molecular Sciences. 21. PMID 32178271 DOI: 10.3390/Ijms21061931  0.386
2020 Yamashita D, Bernstock JD, Elsayed G, Sadahiro H, Mohyeldin A, Chagoya G, Ilyas A, Mooney J, Estevez-Ordonez D, Yamaguchi S, Flanary VL, Hackney JR, Bhat KP, Kornblum HI, Zamboni N, ... ... Chiocca EA, et al. Targeting glioma-initiating cells via the tyrosine metabolic pathway. Journal of Neurosurgery. 1-12. PMID 32059178 DOI: 10.3171/2019.11.Jns192028  0.399
2020 Mineo M, Lyons SM, Ferrer-Luna R, Ito H, Spreckelsen Nv, Alayo QA, Khalsa JK, Shah K, Ligon KL, Beroukhim R, Ivanov P, Anderson PJ, Nakashima H, Lawler SE, Chiocca EA. Abstract B46: The long noncoding RNA INCA1 is a novel regulator of PD-L1 expression in tumors Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm19-B46  0.339
2019 Sette P, Amankulor N, Li A, Marzulli M, Leronni D, Zhang M, Goins WF, Kaur B, Bolyard C, Cripe TP, Yu J, Chiocca EA, Glorioso JC, Grandi P. GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival. Molecular Therapy Oncolytics. 15: 214-222. PMID 31890868 DOI: 10.1016/J.Omto.2019.10.005  0.559
2019 Chiocca EA, Yu JS, Lukas RV, Solomon IH, Ligon KL, Nakashima H, Triggs DA, Reardon DA, Wen P, Stopa BM, Naik A, Rudnick J, Hu JL, Kumthekar P, Yamini B, et al. Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial. Science Translational Medicine. 11. PMID 31413142 DOI: 10.1126/Scitranslmed.Aaw5680  0.349
2019 Lim-Fat MJ, Bi WL, Lo J, Lee EQ, Ahluwalia MS, Batchelor TT, Chang SM, Chiocca EA, Chukwueke U, Cloughesy TF, Colman H, Deangelis LM, Galanis E, Gilbert MR, De Groot JF, et al. Letter: When Less is More: Dexamethasone Dosing for Brain Tumors. Neurosurgery. PMID 31215634 DOI: 10.1093/Neuros/Nyz186  0.351
2019 Nowicki MO, Hayes JL, Chiocca EA, Lawler SE. Proteomic Analysis Implicates Vimentin in Glioblastoma Cell Migration. Cancers. 11. PMID 30987208 DOI: 10.3390/Cancers11040466  0.372
2019 Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. Acs Nano. PMID 30916923 DOI: 10.1021/Acsnano.8B08177  0.406
2019 Krenzlin H, Behera P, Lorenz V, Passaro C, Zdioruk M, Nowicki MO, Grauwet K, Zhang H, Skubal M, Ito H, Zane R, Gutknecht M, Griessl MB, Ricklefs F, Ding L, ... ... Chiocca EA, et al. Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis. The Journal of Clinical Investigation. 130. PMID 30855281 DOI: 10.1172/Jci123375  0.403
2019 Bhaskaran V, Nowicki MO, Idriss M, Jimenez MA, Lugli G, Hayes JL, Mahmoud AB, Zane RE, Passaro C, Ligon KL, Haas-Kogan D, Bronisz A, Godlewski J, Lawler SE, Chiocca EA, et al. The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma. Nature Communications. 10: 442. PMID 30683859 DOI: 10.1038/S41467-019-08390-Z  0.329
2019 Xu B, Ma R, Russell L, Yoo JY, Han J, Cui H, Yi P, Zhang J, Nakashima H, Dai H, Chiocca EA, Kaur B, Caligiuri MA, Yu J. Amendments: Publisher Correction: An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma. Nature Biotechnology. 37: 102. PMID 30605164 DOI: 10.1038/Nbt0119-102C  0.468
2019 Lukas RV, Chiocca EA, Kurz SC, Yu J, Landolfi JC, Rao G, Barrett JA, Buck JY, Demars N, Smith A, Miao J, Zhou Q(, Gelb AB, Cooper L. Evaluation of controlled IL-12 as monotherapy in subjects with recurrent GBM. Journal of Clinical Oncology. 37: 2053-2053. DOI: 10.1200/Jco.2019.37.15_Suppl.2053  0.31
2019 Chiocca EA, Lukas RV, Rao G, Barrett JA, Buck JY, Demars N, Smith A, Miao J, Zhou Q(, Gelb AB, Cooper L. Evaluation of controlled IL-12 in combination with a PD-1 inhibitor in subjects with recurrent glioblastoma. Journal of Clinical Oncology. 37: 2020-2020. DOI: 10.1200/Jco.2019.37.15_Suppl.2020  0.324
2019 Koch M, Zdioruk M, Oskar Nowicki M, Aguilar E, Aguilar L, Guzik B, Chiocca E, Lawler S. IMMU-46. EXAMINATION OF THE EFFECTS OF DEXAMETHASONE ON THE EFFICACY OF IMMUNOTHERAPY IN GLIOMA USING GENE-MEDIATED CYTOTOXIC IMMUNOTHERAPY Neuro-Oncology. 21: vi129-vi129. DOI: 10.1093/neuonc/noz175.538  0.312
2018 Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, ... ... Chiocca EA, et al. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature. PMID 30568305 DOI: 10.1038/S41586-018-0792-9  0.307
2018 Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R. Characterization of single microvesicles in plasma from glioblastoma patients. Neuro-Oncology. PMID 30561734 DOI: 10.1093/Neuonc/Noy187  0.325
2018 Xu B, Ma R, Russell L, Yoo JY, Han J, Cui H, Yi P, Zhang J, Nakashima H, Dai H, Chiocca EA, Kaur B, Caligiuri MA, Yu J. An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma. Nature Biotechnology. PMID 30475349 DOI: 10.1038/Nbt.4302  0.557
2018 Chiocca EA, Nassiri F, Wang J, Peruzzi P, Zadeh G. Viral and other therapies for recurrent GBM: is a 24-month durable response unusual? Neuro-Oncology. PMID 30346600 DOI: 10.1093/Neuonc/Noy170  0.433
2018 Passaro C, Alayo Q, DeLaura I, McNulty JJ, Grauwet K, Ito H, Bhaskaran V, Mineo M, Lawler SE, Shah K, Speranza MC, Goins WF, McLaughlin E, Fernandez S, Reardon DA, ... ... Chiocca EA, et al. Arming an oncolytic herpes simplex virus Type 1 with a single chain fragment variable antibody against PD-1 for experimental glioblastoma therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30279232 DOI: 10.1158/1078-0432.Ccr-18-2311  0.346
2018 Iorgulescu JB, Reardon DA, Chiocca EA, Wu CJ. Immunotherapy for glioblastoma: going viral. Nature Medicine. PMID 30082860 DOI: 10.1038/S41591-018-0142-3  0.351
2018 Nakashima H, Nguyen T, Kasai K, Passaro C, Ito H, Goins WF, Shaikh I, Erdelyi R, Nishihara R, Nakano I, Reardon DA, Anderson AC, Kuchroo V, Chiocca EA. Toxicity and efficacy of a novel GADD34-expressing oncolytic HSV-1 for the treatment of experimental glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29511029 DOI: 10.1158/1078-0432.Ccr-17-2954  0.416
2018 Delaunay T, Violland M, Boisgerault N, Dutoit S, Vignard V, Münz C, Gannage M, Dréno B, Vaivode K, Pjanova D, Labarrière N, Wang Y, Chiocca EA, Boeuf FL, Bell JC, et al. Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells. Oncoimmunology. 7: e1407897. PMID 29399408 DOI: 10.1080/2162402X.2017.1407897  0.437
2018 Nakashima H, Alayo QA, Penaloza-MacMaster P, Freeman GJ, Kuchroo VK, Reardon DA, Fernandez S, Caligiuri M, Chiocca EA. Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells. Scientific Reports. 8: 208. PMID 29317703 DOI: 10.1038/S41598-017-18540-2  0.39
2018 Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca EA, Breakefield XO, Lee H, Weissleder R. Multiplexed Profiling of Single Extracellular Vesicles. Acs Nano. PMID 29286635 DOI: 10.1021/Acsnano.7B07060  0.304
2018 Lebel FM, Barrett JA, McArthur HL, Buck JY, Demars N, Mackenna R, Cooper LJ, Chiocca EA. Demonstration of anti-tumor immunity via intratumoral regulated platform ad-RTS-hIL-12 in advanced breast cancer and recurrent glioblastoma patients. Journal of Clinical Oncology. 36: 3038-3038. DOI: 10.1200/Jco.2018.36.15_Suppl.3038  0.326
2018 Cho C, Ghotmi Y, Fadzan C, Wolfe J, Bergmann S, Qu Y, Murrell E, Bononi F, Luyt L, Chiocca EA, Viapiano M, Pentelute B, Lawler S. DDIS-26. BTP-7, A NOVEL PEPTIDE FOR THERAPEUTIC TARGETING OF MALIGNANT BRAIN TUMORS Neuro-Oncology. 20: vi74-vi74. DOI: 10.1093/Neuonc/Noz175.287  0.356
2018 Alayo Q, Ito H, Passaro C, Zdioruk M, Mahmoud A, Nakashima H, Chiocca EA. Immu-02. Oncolytic Hsv Therapy Enhances Glioblastoma Control Via The Expansion Of Functional Tumor-Specific T Cells And Modulation Of Myeloid Cell Population Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.505  0.382
2018 Ito H, Nakashima H, McLaughlin E, Chiocca EA. Exth-53. In Vivo Quantitative Analysis Of Oncolytic Virus-Tumor Kinetics Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.401  0.403
2018 De Smet F, Tseng Y, Ramkissoon S, Ramkissoon L, Pelton K, Luna RF, Panovska D, Schoolcraft K, Watkinson F, Bilton S, Hung V, Chow K, Geduldig J, Becker S, Jones R, ... ... Chiocca EA, et al. TMOD-14. A PATIENT-DERIVED CANCER CELL LINE ATLAS OF PRIMARY AND METASTATIC CENTRAL NERVOUS SYSTEM TUMORS Neuro-Oncology. 20: vi271-vi271. DOI: 10.1093/Neuonc/Noy148.1126  0.375
2017 Reardon DA, Wucherpfennig K, Chiocca EA. Immunotherapy for glioblastoma: on the sidelines or in the game? Discovery Medicine. 24: 201-208. PMID 29278673  0.328
2017 Nandhu MS, Behera P, Bhaskaran V, Longo SL, Barrera-Arenas LM, Sengupta S, Rodriguez-Gil DJ, Chiocca EA, Viapiano MS. Development of a function-blocking antibody against fibulin-3 as targeted reagent for glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29146721 DOI: 10.1158/1078-0432.Ccr-17-1628  0.346
2017 Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, ... Chiocca EA, et al. Preclinical investigation of gene-mediated cytotoxic immunotherapy and checkpoint blockade in glioblastoma. Neuro-Oncology. PMID 29016938 DOI: 10.1093/Neuonc/Nox139  0.328
2017 Dai HS, Griffin N, Bolyard C, Mao HC, Zhang J, Cripe TP, Suenaga T, Arase H, Nakano I, Chiocca EA, Kaur B, Yu J, Caligiuri MA. The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells. Immunity. 47: 159-170.e10. PMID 28723548 DOI: 10.1016/J.Immuni.2017.06.019  0.448
2017 Rooj AK, Ricklefs F, Mineo M, Nakano I, Chiocca EA, Bronisz A, Godlewski J. MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells. Cell Reports. 19: 2026-2032. PMID 28591575 DOI: 10.1016/J.Celrep.2017.05.040  0.343
2017 Godlewski J, Ferrer-Luna R, Rooj AK, Mineo M, Ricklefs F, Takeda YS, Nowicki MO, Salińska E, Nakano I, Lee H, Weissleder R, Beroukhim R, Chiocca EA, Bronisz A. MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer. Stem Cell Reports. PMID 28528698 DOI: 10.1016/J.Stemcr.2017.04.024  0.304
2017 Teng J, Carla da Hora C, Kantar RS, Nakano I, Wakimoto H, Batchelor TT, Chiocca EA, Badr CE, Tannous BA. Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models. Neuro-Oncology. PMID 28062830 DOI: 10.1093/Neuonc/Now253  0.399
2017 Chiocca EA, Yu J, Phuphanich S, Lukas RV, Kumthekar P, Yang Y, Zhou Q(, Buck JY, Deary A, Cai H, Barrett JA, Cooper LJ, Lebel FM. Expanded phase I study of intratumoral Ad-RTS-hIL-12 plus oral veledimex: Tolerability and survival in recurrent glioblastoma. Journal of Clinical Oncology. 35: 2044-2044. DOI: 10.1200/Jco.2017.35.15_Suppl.2044  0.315
2017 Speranza MC, Ricklefs F, Passaro C, Klein SR, Kasai K, Kaufmann J, Nakashima H, Agnieszka B, Aguilar-Cordova E, Guzik BW, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE. Abstract B84: Preclinical analysis of combinatorial glioblastoma therapy with the prodrug-mediated gene therapy vector AdV-TK and immune checkpoint inhibition Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B84  0.426
2017 Alayo Q, Passaro C, McNulty J, Hiroshi N, Chiocca EA. Immu-12. The Histone Deacetylase Inhibitor Valproic Acid Augments The Susceptibility Of Oncolytic Virus-Infected Glioblastoma Cells To Pd-1 Blockade Therapy Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.471  0.303
2017 Cho C, Ghotmi Y, Fazden C, Wolfe J, Bononi F, Murrell E, Luyt L, Viapiano M, Pentelute B, Chiocca EA, Lawler SE. DDIS-19. NOVEL PEPTIDE HOMING TO GLIOMA-SPECIFIC ISOFORM OF BREVICAN SELECTIVELY TARGETS MALIGNANT BRAIN TUMORS Neuro-Oncology. 19: vi62-vi63. DOI: 10.1093/Neuonc/Nox168.254  0.356
2016 Lawler SE, Speranza MC, Cho CF, Chiocca EA. Oncolytic Viruses in Cancer Treatment: A Review. Jama Oncology. PMID 27441411 DOI: 10.1001/Jamaoncol.2016.2064  0.41
2016 Mineo M, Ricklefs F, Rooj AK, Lyons SM, Ivanov P, Ansari KI, Nakano I, Chiocca EA, Godlewski J, Bronisz A. The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches. Cell Reports. PMID 27264189 DOI: 10.1016/J.Celrep.2016.05.018  0.372
2016 Chen X, Han J, Chu J, Zhang L, Zhang J, Chen C, Chen L, Wang Y, Wang H, Yi L, Elder JB, Wang QE, He X, Kaur B, Chiocca EA, et al. A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases. Oncotarget. PMID 27050072 DOI: 10.18632/Oncotarget.8526  0.568
2016 Ricklefs F, Mineo M, Rooj AK, Nakano I, Charest A, Weissleder R, Breakefield XO, Chiocca EA, Godlewski J, Bronisz A. Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity. Cancer Research. PMID 27013191 DOI: 10.1158/0008-5472.CAN-15-3432  0.302
2016 Bronisz A, Godlewski J, Chiocca EA. Extracellular Vesicles and MicroRNAs: Their Role in Tumorigenicity and Therapy for Brain Tumors. Cellular and Molecular Neurobiology. 36: 361-76. PMID 26983830 DOI: 10.1007/S10571-015-0293-4  0.424
2016 Hulou MM, Cho CF, Chiocca EA, Bjerkvig R. Experimental therapies: gene therapies and oncolytic viruses. Handbook of Clinical Neurology. 134: 183-97. PMID 26948355 DOI: 10.1016/B978-0-12-802997-8.00011-6  0.344
2016 Speranza MC, Nowicki MO, Behera P, Cho CF, Chiocca EA, Lawler SE. BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma. Scientific Reports. 6: 20189. PMID 26846842 DOI: 10.1038/Srep20189  0.377
2016 Wheeler LA, Manzanera AG, Bell SD, Cavaliere R, McGregor JM, Grecula JC, Newton HB, Lo SS, Badie B, Portnow J, Teh BS, Trask TW, Baskin DS, New PZ, Aguilar LK, ... Chiocca EA, et al. Phase 2 multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma. Neuro-Oncology. PMID 26843484 DOI: 10.1093/Neuonc/Now002  0.343
2016 Lebel FM, Barrett JA, Chiocca EA, Yu J, Lukas RV, Nagpal S, Kumthekar P, Krishnan S, Cooper LJ. Effect of controlled intratumoral viral delivery of Ad-RTS-hIL-12 + oral veledimex in subjects with recurrent or progressive glioma. Journal of Clinical Oncology. 34: 2052-2052. DOI: 10.1200/Jco.2016.34.15_Suppl.2052  0.314
2016 Speranza MC, Kasai K, Ricklefs F, Klein SR, Passaro C, Nakashima H, Kaufmann J, Bronisz A, Aguilar-Cordova E, Guzik BW, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE. Abstract A075: Preclinical analysis of combinatorial glioblastoma therapy with the prodrug-mediated gene therapy vector AdV-TK and immune checkpoint inhibition in GBM therapy Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A075  0.385
2016 Mineo M, Ricklefs F, Lyons SS, Ivanov P, Chiocca EA, Godlewski J, Bronisz A. Abstract PR04: The role of long noncoding RNA HIF1A-AS2 in hypoxic environment of glioblastoma Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Pr04  0.354
2016 Baskin DS, Aguilar LK, Wheeler LA, Manzanera AG, Bell SD, Cavaliere R, McGregor JM, Lo SS, Grecula JC, Newton HB, Badie B, Teh BS, Butler EB, Trask TW, Portnow J, ... ... Chiocca EA, et al. Abstract CT110: Phase II multicenter study of gene-mediated cytotoxic immunotherapy as an adjuvant to surgical resection for newly diagnosed malignant glioma: lessons learned from pseudo-progression and a nine-year survivor Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ct110  0.413
2016 Speranza MC, Kasai K, Kaufmann J, Aguilar-Cordova E, Guzik BW, Chiocca EA, Lawler S. Abstract 2349: Evaluation of the combination of the prodrug-mediated gene therapy vector AdV-tk and immune checkpoint inhibitor for glioblastoma treatment in a syngeneic mouse model Cancer Research. 76: 2349-2349. DOI: 10.1158/1538-7445.Am2016-2349  0.444
2016 Nakashima H, Alayo Q, Penaloza P, Barouch D, Chiocca EA. Tmod-20. Establishment Of A Brain Tumor Model With Dysfunctional Tumor Immunity In Mice As A Platform For Immunotherapeutic Evaluation Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.890  0.389
2016 Sengupta S, Mohan N, Chiocca EA, Sampath P, Viapiano M. IMST-05. NOVEL CAR-T CELLS TARGETING THE EXTRACELLULAR MATRIX OF GLIOBLASTOMA INDUCE STRONG ANTI-TUMOR IMMUNE RESPONSE Neuro-Oncology. 18: vi86-vi87. DOI: 10.1093/Neuonc/Now212.362  0.367
2016 Zhang Y, Chiocca EA. Exth-38. A Triplet Bioluminescence Imaging System Real-Time Reveals Viral Infection, Replication And Tumor Viability In Vivo Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.282  0.363
2016 Speranza MC, Kasai K, Ricklefs F, Klein SR, Passaro C, Hiroshi N, Kaufmann J, Bronisz A, Aguilar-Cordova E, Guzik BW, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE. EXTH-23. PRECLINICAL ANALYSIS OF COMBINATORIAL GLIOBLASTOMA THERAPY WITH THE PRODRUG-MEDIATED GENE THERAPY VECTOR AdV-tk AND IMMUNE CHECKPOINT INHIBITION Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.267  0.309
2016 Peters C, Nigim F, Chiocca EA, Rabkin SD. Oncolytic viruses on the cusp of success?: proceedings of the 9th International Conference on Oncolytic Virus Therapeutics Molecular Therapy - Oncolytics. 3: 16016. DOI: 10.1038/Mto.2016.16  0.387
2015 Han J, Chen X, Chu J, Xu B, Meisen WH, Chen L, Zhang L, Zhang J, He X, Wang QE, Chiocca EA, Kaur B, Caligiuri MA, Yu J. TGFβ Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response. Cancer Research. PMID 26631269 DOI: 10.1158/0008-5472.Can-15-0894  0.6
2015 Nakashima H, Kaufmann JK, Wang PY, Nguyen T, Speranza MC, Kasai K, Okemoto K, Otsuki A, Nakano I, Fernandez S, Goins WF, Grandi P, Glorioso JC, Lawler S, Cripe TP, ... Chiocca EA, et al. Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma. The Journal of Clinical Investigation. 125: 4269-80. PMID 26524593 DOI: 10.1172/Jci80713  0.471
2015 Singh M, Ricci JA, Talbot SG, Chiocca EA, Dunn IF, Caterson EJ. Reconstruction of Rare Skull Metastases Using Free Latissimus Dorsi Flap and the Role of Preoperative Embolization in Hypervascular Skull Tumors. The Journal of Craniofacial Surgery. PMID 26501975 DOI: 10.1097/Scs.0000000000002218  0.357
2015 Bronisz A, Chiocca EA, Godlewski J. Response to energy depletion: miR-451/AMPK loop. Oncotarget. 6: 17851-2. PMID 26257001 DOI: 10.18632/Oncotarget.4606  0.307
2015 Lawler SE, Chiocca EA. Oncolytic Virus-Mediated Immunotherapy: A Combinatorial Approach for Cancer Treatment. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2812-4. PMID 26215964 DOI: 10.1200/Jco.2015.62.5244  0.309
2015 Han J, Chu J, Keung Chan W, Zhang J, Wang Y, Cohen JB, Victor A, Meisen WH, Kim SH, Grandi P, Wang QE, He X, Nakano I, Chiocca EA, Glorioso Iii JC, et al. CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells. Scientific Reports. 5: 11483. PMID 26155832 DOI: 10.1038/Srep11483  0.569
2015 Forsyth TM, Bi WL, Abedalthagafi M, Dunn IF, Chiocca EA. Extracranial growth of glioblastoma multiforme. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 22: 1521-3. PMID 25956620 DOI: 10.1016/J.Jocn.2015.03.018  0.38
2015 Bronisz A, Chiocca EA. A cross-talk network that facilitates tumor virotherapy. Nature Medicine. 21: 426-7. PMID 25951527 DOI: 10.1038/Nm.3857  0.383
2015 Ansari KI, Ogawa D, Rooj AK, Lawler SE, Krichevsky AM, Johnson MD, Chiocca EA, Bronisz A, Godlewski J. Glucose-based regulation of miR-451/AMPK signaling depends on the OCT1 transcription factor. Cell Reports. 11: 902-9. PMID 25937278 DOI: 10.1016/J.Celrep.2015.04.016  0.32
2015 Alvarez-Breckenridge CA, Choi BD, Suryadevara CM, Chiocca EA. Potentiating oncolytic viral therapy through an understanding of the initial immune responses to oncolytic viral infection. Current Opinion in Virology. 13: 25-32. PMID 25846988 DOI: 10.1016/J.Coviro.2015.03.015  0.352
2015 Godlewski J, Krichevsky AM, Johnson MD, Chiocca EA, Bronisz A. Belonging to a network--microRNAs, extracellular vesicles, and the glioblastoma microenvironment. Neuro-Oncology. 17: 652-62. PMID 25301812 DOI: 10.1093/Neuonc/Nou292  0.385
2015 Mazzacurati L, Marzulli M, Reinhart B, Miyagawa Y, Uchida H, Goins WF, Li A, Kaur B, Caligiuri M, Cripe T, Chiocca EA, Chiocca N, Amankulor N, Cohen JB, Glorioso JC, et al. Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 99-107. PMID 25200130 DOI: 10.1038/Mt.2014.177  0.459
2015 Aguilar LK, Wheeler LA, Manzanera AG, Bell SD, Cavaliere R, McGregor JM, Lo S, Grecula JC, Newton HB, Badie B, Trask TW, Baskin DS, Portnow J, New PZ, Aguilar-Cordova E, ... Chiocca EA, et al. Phase II multicenter study of gene mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma. Journal of Clinical Oncology. 33: 2010-2010. DOI: 10.1200/Jco.2015.33.15_Suppl.2010  0.367
2015 Xilin C, Han J, Jianhong C, Meisen W, Jianying Z, Chiocca EA, Kaur B, Caligiuri MA, Yu J. Modulation of Natural Killer Cell Activity in the Setting of Oncolytic Virotherapy and with a Chimeric Antigen Receptor Blood. 126: 210-210. DOI: 10.1182/Blood.V126.23.210.210  0.596
2015 Pont LMB, Balvers R, Kloezeman J, Nowicki MO, Kremer A, Chiocca EA, Leenstra S, Dirven CM, Lawler S, Lamfers ML. Abstract 299: In vitro compound screening identifies enhancers of adenoviral oncolysis with Delta24-RGD in patient-derived glioblastoma stem cells Cancer Research. 75: 299-299. DOI: 10.1158/1538-7445.Am2015-299  0.387
2015 Speranza MC, Nowicki MO, Cho C, Chiocca EA, Lawler SE. Abstract LB-B19: BKM-120: a phosphatidyl-inositol-3 kinase inhibitor with anti-migratory properties in glioblastoma Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Lb-B19  0.427
2015 Rooj A, Peruzzi P, Bronisz A, Chiocca EA, Godlewski J. STEM-09MicroRNA-128 IS A MASTER SWITCH BETWEEN PRONEURAL AND MESENCHYMAL SUBTYPE IN GLIOBLASTOMA STEM CELLS Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov234.09  0.302
2015 Speranza M, Kasai K, Kaufmann J, Nakashima H, Lawler S, Chiocca EA. IMPS-21EFFECT OF rQNestin 34.5 ONCOLYTIC HERPES VIRUS ON IMMUNE CHECKPOINT GENE EXPRESSION IN GLIOBLASTOMA CELLS AND EVALUATION OF THERAPEUTIC EFFICACY Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov217.21  0.38
2015 Barrett JA, Cai H, Miao J, Murray M, Gable E, Blake D, Krishnan S, Chiocca EA, Nagpal S, Raizer J, Yu J, Lebel F. Imps-03Intratumoral Regulated Expression Of Il-12 As A Gene Therapy Approach To Treatment Of Glioma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov217.03  0.365
2015 Kalkanis SN, Aghi MK, Cloughsy TF, Kaptain G, Portnow J, Vogelbaum MA, Kesari S, Mikkelsen T, Elder JB, Chen CC, Piccioni D, Baskin D, Engh J, Bota D, Chiocca EA, et al. Ddel-06Preliminary Safety Of Toca 511, A Retroviral Replicating Vector, In Patients With Recurrent High Grade Glioma Across Three Separate Phase 1 Studies Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov212.06  0.343
2015 Bronisz A, Mineo M, Ferrer-Luna R, Chiocca EA, Godlewski J. CBM-01CHARACTERIZATION OF microRNAome IN GLIOBLASTOMA STEM CELLS AND THEIR EXTRACELLULAR VESICLES Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov211.01  0.387
2015 Zhang Y, Chiocca EA, Nakashima H. Atps-98Monitoring Oncolytic Hsv-1 With Non-Invasive Bioluminescence Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov204.98  0.388
2015 Cho C, Bononi F, Wolfe J, Pentelute B, Luyt L, Viapiano M, Chiocca EA, Lawler S. ATPS-08DISCOVERY OF NOVEL GLIOMA-TARGETING PEPTIDES USING A HIGH-THROUGHPUT MICROFLUIDIC MAGNETIC-ACTIVATED SORTER Neuro-Oncology. 17: v19.4-v19. DOI: 10.1093/Neuonc/Nov204.08  0.321
2014 Reardon DA, Freeman G, Wu C, Chiocca EA, Wucherpfennig KW, Wen PY, Fritsch EF, Curry WT, Sampson JH, Dranoff G. Immunotherapy advances for glioblastoma. Neuro-Oncology. 16: 1441-58. PMID 25190673 DOI: 10.1093/Neuonc/Nou212  0.385
2014 Abd-El-Barr MM, Chiocca EA. How much is enough? The question of extent of resection in glioblastoma multiforme. World Neurosurgery. 82: e109-10. PMID 24813127 DOI: 10.1016/J.Wneu.2014.05.006  0.355
2014 Bi WL, Chiocca EA. Image-guided maximal resection of intrinsic tumors. World Neurosurgery. 82: 604-5. PMID 24802845 DOI: 10.1016/J.Wneu.2014.04.070  0.341
2014 Chiocca EA, Rabkin SD. Oncolytic viruses and their application to cancer immunotherapy. Cancer Immunology Research. 2: 295-300. PMID 24764576 DOI: 10.1158/2326-6066.CIR-14-0015  0.309
2014 Chiocca EA, Blair D, Mufson RA. Oncolytic viruses targeting tumor stem cells. Cancer Research. 74: 3396-8. PMID 24753541 DOI: 10.1158/0008-5472.Can-14-0290  0.389
2014 Nakashima H, Chiocca EA. Modification of HSV-1 to an oncolytic virus. Methods in Molecular Biology (Clifton, N.J.). 1144: 117-27. PMID 24671680 DOI: 10.1007/978-1-4939-0428-0_8  0.316
2014 Kicielinski KP, Chiocca EA, Yu JS, Gill GM, Coffey M, Markert JM. Phase 1 clinical trial of intratumoral reovirus infusion for the treatment of recurrent malignant gliomas in adults. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1056-62. PMID 24553100 DOI: 10.1038/Mt.2014.21  0.319
2014 Kaufmann JK, Chiocca EA. Glioma virus therapies between bench and bedside Neuro-Oncology. 16: 334-351. PMID 24470549 DOI: 10.1093/Neuonc/Not310  0.443
2014 Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, ... ... Chiocca EA, et al. Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma. Cancer Research. 74: 1752-65. PMID 24453002 DOI: 10.1158/0008-5472.Can-13-0884  0.584
2014 Robbins JM, Huang TT, Jolly DJ, Kasahara N, Aghi MK, Vogelbaum MA, Cloughesy TF, Chang SM, Kesari S, Mikkelsen T, Kalkanis SN, Landolfi JC, Elder JB, Chiocca EA, Gruber HE, et al. Ascending dose trials of a retroviral replicating vector (Toca 511) in patients with recurrent high-grade glioma. Journal of Clinical Oncology. 32: 3078-3078. DOI: 10.1200/Jco.2014.32.15_Suppl.3078  0.42
2014 Cloughesy TF, Kesari S, Kalkanis S, Mikkelsen T, Landolfi J, Elder JB, Liau LM, Chen CC, Bloomfield S, Piccioni D, Chiocca EA, Foltz G, Robbins JM, Ostertag D, Jolly DJ, et al. IT-05 * ADMINISTRATION OF TOCA 511 TO SUBJECTS WITH RECURRENT HGG UNDERGOING REPEAT RESECTION Neuro-Oncology. 16: v110-v111. DOI: 10.1093/Neuonc/Nou258.4  0.409
2014 Nandhu M, Behera P, Chiocca EA, Viapiano M. ET-42 * DEVELOPMENT OF A NOVEL, FUNCTION-BLOCKING ANTI-FIBULIN-3 ANTIBODY AS TARGETED REAGENT FOR GLIOBLASTOMA Neuro-Oncology. 16: v88-v88. DOI: 10.1093/Neuonc/Nou255.42  0.385
2014 Kaufmann JK, Nakashima H, Nguyen T, Wang P, Nakano I, Cripe TP, Chiocca EA. Et-27Replication And Spread Of Oncolytic Herpes Virus In Glioma Stem Cells Can Be Enhanced By Specific Inhibition Of Histone Deacetylase 6 Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou255.27  0.424
2014 Bronisz A, Mineo M, Ansari K, Rooj A, Nakano I, Chiocca EA, Godlewski J. BI-03GLIOBLASTOMA-SPECIFIC AND GLIOBLASTOMA STEM CELL SUBTYPE-SPECIFIC SIGNATURES OF LONG, NON-CODING RNAs Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou239.3  0.318
2013 Kaufmann JK, Chiocca EA. Oncolytic virotherapy for gliomas: steps toward the future. Cns Oncology. 2: 389-92. PMID 25054659 DOI: 10.2217/Cns.13.35  0.474
2013 Kwiatkowska A, Nandhu MS, Behera P, Chiocca EA, Viapiano MS. Strategies in gene therapy for glioblastoma. Cancers. 5: 1271-305. PMID 24202446 DOI: 10.3390/Cancers5041271  0.39
2013 Okemoto K, Kasai K, Wagner B, Haseley A, Meisen H, Bolyard C, Mo X, Wehr A, Lehman A, Fernandez S, Kaur B, Chiocca EA. DNA demethylating agents synergize with oncolytic HSV1 against malignant gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5952-9. PMID 24056786 DOI: 10.1158/1078-0432.CCR-12-3588  0.506
2013 Okemoto K, Wagner B, Meisen H, Haseley A, Kaur B, Chiocca EA. STAT3 activation promotes oncolytic HSV1 replication in glioma cells. Plos One. 8: e71932. PMID 23936533 DOI: 10.1371/Journal.Pone.0071932  0.503
2013 Kasai K, Nakashima H, Liu F, Kerr S, Wang J, Phelps M, Potter PM, Goins WB, Fernandez SA, Chiocca EA. Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs. Molecular Therapy. Nucleic Acids. 2: e113. PMID 23922029 DOI: 10.1038/Mtna.2013.38  0.389
2013 Fujii K, Kurozumi K, Ichikawa T, Onishi M, Shimazu Y, Ishida J, Chiocca EA, Kaur B, Date I. The integrin inhibitor cilengitide enhances the anti-glioma efficacy of vasculostatin-expressing oncolytic virus. Cancer Gene Therapy. 20: 437-44. PMID 23827879 DOI: 10.1038/Cgt.2013.38  0.542
2013 Reardon DA, Wucherpfennig KW, Freeman G, Wu CJ, Chiocca EA, Wen PY, Curry WT, Mitchell DA, Fecci PE, Sampson JH, Dranoff G. An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma. Expert Review of Vaccines. 12: 597-615. PMID 23750791 DOI: 10.1586/Erv.13.41  0.354
2013 Alvarez-Breckenridge CA, Yu J, Caligiuri MA, Chiocca EA. Uncovering a novel mechanism whereby NK cells interfere with glioblastoma virotherapy. Oncoimmunology. 2: e23658. PMID 23734319 DOI: 10.4161/Onci.23658  0.37
2013 Price RL, Song J, Bingmer K, Kim TH, Yi JY, Nowicki MO, Mo X, Hollon T, Murnan E, Alvarez-Breckenridge C, Fernandez S, Kaur B, Rivera A, Oglesbee M, Cook C, ... Chiocca EA, et al. Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations. Cancer Research. 73: 3441-50. PMID 23729642 DOI: 10.1093/Neuonc/Nou206.27  0.539
2013 Onishi M, Kurozumi K, Ichikawa T, Michiue H, Fujii K, Ishida J, Shimazu Y, Chiocca EA, Kaur B, Date I. Gene expression profiling of the anti-glioma effect of Cilengitide. Springerplus. 2: 160. PMID 23667810 DOI: 10.1186/2193-1801-2-160  0.534
2013 Tanabe KK, Chiocca EA. "Infectious" optimism for treatment of hepatocellular carcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 722-4. PMID 23542566 DOI: 10.1038/Mt.2013.47  0.456
2013 Ikeda D, Chiocca EA. Editorial: Tumor and antiepileptic drugs: clinical article. Journal of Neurosurgery. 118: 1181-2; discussion 1. PMID 23451908 DOI: 10.3171/2012.8.Jns121332  0.34
2013 Dunn IF, Chiocca EA. Stereotactic radiosurgery and atypical meningiomas Journal of Neurosurgery. 119: 472-474. PMID 23394338 DOI: 10.3171/2012.8.Jns121566  0.342
2013 Maruo T, Ichikawa T, Kanzaki H, Inoue S, Kurozumi K, Onishi M, Yoshida K, Kambara H, Ouchida M, Shimizu K, Tamaru S, Chiocca EA, Date I. Proteomics-based analysis of invasion-related proteins in malignant gliomas. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 33: 264-75. PMID 23116197 DOI: 10.1111/J.1440-1789.2012.01361.X  0.344
2013 Uchida H, Marzulli M, Nakano K, Goins WF, Chan J, Hong CS, Mazzacurati L, Yoo JY, Haseley A, Nakashima H, Baek H, Kwon H, Kumagai I, Kuroki M, Kaur B, ... Chiocca EA, et al. Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 561-9. PMID 23070115 DOI: 10.1038/Mt.2012.211  0.619
2013 Onishi M, Ichikawa T, Kurozumi K, Fujii K, Yoshida K, Inoue S, Michiue H, Chiocca EA, Kaur B, Date I. Bimodal anti-glioma mechanisms of cilengitide demonstrated by novel invasive glioma models. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 33: 162-74. PMID 22989076 DOI: 10.1111/J.1440-1789.2012.01344.X  0.603
2013 Peruzzi P, Chiocca EA. Understanding glioma invasion: a necessity for effective therapy. World Neurosurgery. 80: 281-3. PMID 22120237 DOI: 10.1016/J.Wneu.2011.10.003  0.441
2013 Godlewski JA, Bronisz A, Wang Y, Chiocca EA. Abstract 5336: Targeting glioma growth and invasiveness by microRNA-1. Cancer Research. 73: 5336-5336. DOI: 10.1158/1538-7445.Am2013-5336  0.382
2013 Price RL, Bingmer K, Harkins L, Iwenofu H, Kwon C, Cook C, Pelloski C, Chiocca EA. Abstract 4777: Cytomegalovirus infection leads to pleomorphic rhabdomyosarcomas in Trp53 +/- mice. Cancer Research. 73: 4777-4777. DOI: 10.1158/1538-7445.Am2013-4777  0.378
2013 Lawler SE, Nowicki MO, Chiocca EA. Abstract B167: Targeting glioblastoma invasion with GSK-3 inhibitors: Rapid effects on vimentin dynamics. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B167  0.397
2013 Adachi K, Sasaki H, Nagahisa S, Yoshida K, Hattori N, Nishiyama Y, Kawase T, Hasegawa M, Abe M, Hirose Y, Alentorn A, Marie Y, Poggioli S, Alshehhi H, Boisselier B, ... ... Chiocca EA, et al. OMICS AND PROGNSTIC MARKERS Neuro-Oncology. 15: iii136-iii155. DOI: 10.1093/Neuonc/Not183  0.42
2013 Aaberg-Jessen C, Fogh L, Halle B, Jensen V, Brunner N, Kristensen BW, Abe T, Momii Y, Watanabe J, Morisaki I, Natsume A, Wakabayashi T, Fujiki M, Aldaz B, Fabius AWM, ... ... Chiocca E, et al. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 15: iii37-iii61. DOI: 10.1093/Neuonc/Not176  0.398
2012 Alvarez-Breckenridge CA, Yu J, Price R, Wojton J, Pradarelli J, Mao H, Wei M, Wang Y, He S, Hardcastle J, Fernandez SA, Kaur B, Lawler SE, Vivier E, Mandelboim O, ... ... Chiocca EA, et al. NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nature Medicine. 18: 1827-34. PMID 23178246 DOI: 10.1038/Nm.3013  0.56
2012 Price RL, Bingmer K, Harkins L, Iwenofu OH, Kwon CH, Cook C, Pelloski C, Chiocca EA. Cytomegalovirus infection leads to pleomorphic rhabdomyosarcomas in Trp53+/- mice. Cancer Research. 72: 5669-74. PMID 23002204 DOI: 10.1158/0008-5472.Can-12-2425  0.355
2012 Gatson NN, Chiocca EA, Kaur B. Anti-angiogenic gene therapy in the treatment of malignant gliomas. Neuroscience Letters. 527: 62-70. PMID 22906922 DOI: 10.1016/J.Neulet.2012.08.001  0.599
2012 Aguilar LK, Arvizu M, Aguilar-Cordova E, Chiocca EA. The spectrum of vaccine therapies for patients with glioblastoma multiforme. Current Treatment Options in Oncology. 13: 437-50. PMID 22903697 DOI: 10.1007/S11864-012-0208-2  0.384
2012 Ikeda D, Chiocca EA. Editorial: dural tail sign. Journal of Neurosurgery. 117: 643-4. PMID 22839655 DOI: 10.3171/2012.2.Jns12266  0.312
2012 Yoo JY, Pradarelli J, Haseley A, Wojton J, Kaka A, Bratasz A, Alvarez-Breckenridge CA, Yu JG, Powell K, Mazar AP, Teknos TN, Chiocca EA, Glorioso JC, Old M, Kaur B. Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4931-41. PMID 22753591 DOI: 10.1158/1078-0432.Ccr-12-0697  0.583
2012 Porensky P, Chiocca EA. Stage IV melanoma. Journal of Neurosurgery. 117: 225-6; discussion 22. PMID 22702483 DOI: 10.3171/2012.2.Jns1288  0.32
2012 Alvarez-Breckenridge CA, Yu J, Price R, Wei M, Wang Y, Nowicki MO, Ha YP, Bergin S, Hwang C, Fernandez SA, Kaur B, Caligiuri MA, Chiocca EA. The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon. Journal of Virology. 86: 4566-77. PMID 22318143 DOI: 10.1128/Jvi.05545-11  0.575
2012 Alvarez-Breckenridge CA, Yu J, Kaur B, Caligiuri MA, Chiocca EA. Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells. Advances in Virology. 2012: 702839. PMID 22312364 DOI: 10.1155/2012/702839  0.562
2012 Inoue S, Ichikawa T, Kurozumi K, Maruo T, Onishi M, Yoshida K, Fujii K, Kambara H, Chiocca EA, Date I. Novel animal glioma models that separately exhibit two different invasive and angiogenic phenotypes of human glioblastomas. World Neurosurgery. 78: 670-82. PMID 22120277 DOI: 10.1016/J.Wneu.2011.09.005  0.382
2012 Yoo JY, Haseley A, Bratasz A, Chiocca EA, Zhang J, Powell K, Kaur B. Antitumor efficacy of 34.5ENVE: a transcriptionally retargeted and "Vstat120"-expressing oncolytic virus. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 287-97. PMID 22031239 DOI: 10.1038/Mt.2011.208  0.604
2012 Kaur B, Chiocca EA, Cripe TP. Oncolytic HSV-1 virotherapy: clinical experience and opportunities for progress. Current Pharmaceutical Biotechnology. 13: 1842-51. PMID 21740359 DOI: 10.2174/138920112800958814  0.531
2012 Price RL, Song J, Bingmer K, Yi J, Rivera A, Ogelsbee M, Cook C, Kwon C, Chiocca EA. Abstract 4815: Cytomegalovirus enhances glioblastoma via PDGF-B/STAT3 pathway activation Cancer Research. 72: 4815-4815. DOI: 10.1158/1538-7445.Am2012-4815  0.351
2012 Yang FH, Zhang B, Zhou DJ, Bie L, Tom MW, Drummond DC, Nicolaides T, Mueller S, Banerjee A, Park JW, Prados MD, James DC, Gupta N, Hashizume R, Strohbehn GW, ... ... Chiocca EA, et al. LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 14: vi25-vi37. DOI: 10.1093/Neuonc/Nos222  0.489
2012 Birks S, Altinkaya M, Altinkaya A, Pilkington G, Kurian KM, Crosby C, Hopkins K, Williams M, Donovan L, Birks S, Eason A, Bosak V, Pilkington G, Birks S, Holliday J, ... Chiocca EA, et al. Abstracts from the 2012 BNOS Conference Neuro-Oncology. 14: ii1-ii12. DOI: 10.1093/Neuonc/Nos198  0.318
2011 Elder JB, Chiocca EA. Meningioma-toward an improved understanding of the role of sex steroids in tumor development and progression. World Neurosurgery. 76: 409-11. PMID 22152567 DOI: 10.1016/J.Wneu.2011.05.005  0.381
2011 Makary M, Chiocca EA, Erminy N, Antor M, Bergese SD, Abdel-Rasoul M, Fernandez S, Dzwonczyk R. Clinical and economic outcomes of low-field intraoperative MRI-guided tumor resection neurosurgery Journal of Magnetic Resonance Imaging. 34: 1022-1030. PMID 22002753 DOI: 10.1002/Jmri.22739  0.312
2011 Chiocca EA, Aguilar LK, Bell SD, Kaur B, Hardcastle J, Cavaliere R, McGregor J, Lo S, Ray-Chaudhuri A, Chakravarti A, Grecula J, Newton H, Harris KS, Grossman RG, Trask TW, et al. Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3611-9. PMID 21844505 DOI: 10.1200/Jco.2011.35.5222  0.565
2011 Alvarez-Breckenridge C, Chiocca EA. A viral strategy to ambush tumors Nature Medicine. 17: 784-785. PMID 21738155 DOI: 10.1038/Nm0711-784  0.355
2011 Williams SP, Nowicki MO, Liu F, Press R, Godlewski J, Abdel-Rasoul M, Kaur B, Fernandez SA, Chiocca EA, Lawler SE. Indirubins decrease glioma invasion by blocking migratory phenotypes in both the tumor and stromal endothelial cell compartments. Cancer Research. 71: 5374-80. PMID 21697283 DOI: 10.1158/0008-5472.Can-10-3026  0.581
2011 Dmitrieva N, Yu L, Viapiano M, Cripe TP, Chiocca EA, Glorioso JC, Kaur B. Chondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1362-72. PMID 21177410 DOI: 10.1158/1078-0432.Ccr-10-2213  0.6
2011 Nakano I, Chiocca EA. Finding drugs against CD133+ glioma subpopulations. Journal of Neurosurgery. 114: 648; discussion 648-. PMID 21054138 DOI: 10.3171/2009.11.Jns091668  0.391
2011 Kahn J, Loeffler JS, Niemierko A, Chiocca EA, Batchelor T, Chakravarti A. Long-term outcomes of patients with spinal cord gliomas treated by modern conformal radiation techniques International Journal of Radiation Oncology Biology Physics. 81: 232-238. PMID 20947265 DOI: 10.1016/J.Ijrobp.2010.05.009  0.301
2011 Godlewski JA, Bronisz A, Brocklyn JV, Wang Y, Lawler S, Chiocca EA. Abstract 3963: MicroRNA-124 and microRNA-1, commonly lost in glioma, coordinately target sphingosine kinase-1 in glioma cells Cancer Research. 71: 3963-3963. DOI: 10.1158/1538-7445.Am2011-3963  0.384
2011 Pavel H, Ajeawung N, Faure R, Poirier D, Kamnasaran D, Ajeawung N, Joshi H, Kamnasaran D, Poirier D, Ajeawung N, Kamnasaran D, Lun X, Zemp F, Sun B, Stechishin O, ... Chiocca EA, et al. PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 13: iii107-iii120. DOI: 10.1093/Neuonc/Nor158  0.513
2011 Ngwenya LB, Chiocca EA. Adverse events in multimodal treatment therapies for high-grade gliomas World Neurosurgery. 76: 67-68. DOI: 10.1016/J.Wneu.2010.11.018  0.305
2010 Godlewski J, Bronisz A, Nowicki MO, Chiocca EA, Lawler S. microRNA-451: A conditional switch controlling glioma cell proliferation and migration. Cell Cycle (Georgetown, Tex.). 9: 2742-8. PMID 20647762 DOI: 10.4161/Cc.9.14.12248  0.32
2010 Schwartzbaum JA, Huang K, Lawler S, Ding B, Yu J, Chiocca EA. Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma. Neuro-Oncology. 12: 320-7. PMID 20308310 DOI: 10.1093/Neuonc/Nop035  0.308
2010 Nakashima H, Kaur B, Chiocca EA. Directing systemic oncolytic viral delivery to tumors via carrier cells. Cytokine & Growth Factor Reviews. 21: 119-26. PMID 20226717 DOI: 10.1016/J.Cytogfr.2010.02.004  0.539
2010 Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B. Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1 Molecular Therapy. 18: 285-294. PMID 19844198 DOI: 10.1038/Mt.2009.232  0.618
2010 Williams SP, Nowicki MO, Chiocca EA, Lawler SE. Abstract LB-293: Indirubins decrease glioma growth and invasionin vivo:A novel treatment paradigm combining antimigratory and antiangiogenic effects Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-293  0.443
2010 Yan F, Alinari L, Lustberg M, Martin LK, Nowicki O, Wu X, Yu B, Gordon K, Wolfson A, Ryu J, Kaur B, Kwon C, Lawler S, Nuovo G, Liu S, ... ... Chiocca EA, et al. Abstract 1584: Targeting protein arginine methyltransferase 5 (PRMT5) enzyme over expression in high grade astrocytomas Cancer Research. 70: 1584-1584. DOI: 10.1158/1538-7445.Am10-1584  0.573
2010 Alvarez-Breckenridge CA, Yu J, Pradarelli J, Liu T, Kaur B, Caligiuri M, Chiocca EA. Abstract 1514: Oncolytic viral therapy for glioblastoma induces robust natural killer cell activation Cancer Research. 70: 1514-1514. DOI: 10.1158/1538-7445.Am10-1514  0.569
2010 Kaka A, Pradarelli JC, Alvarez-Breckenridge C, Yoo JY, Pan Q, Chiocca EA, Old M, Teknos T, Kaur B. Abstract 1383: The effect of a novel angiogenesis inhibitor (TM) on the efficacy of HSV-1 oncolytic virus Cancer Research. 70: 1383-1383. DOI: 10.1158/1538-7445.Am10-1383  0.58
2010 Asadi-Moghaddam K, Chiocca EA. Brain Surgery for Elders Nejm Journal Watch. 2010. DOI: 10.1056/Jn201003230000002  0.308
2009 Tannous BA, Chiocca EA, Jacobs AH, Corey DP, Breakefield XO. Tannous et al. Respond. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1311-1312. PMID 28160907 DOI: 10.1038/Mt.2009.166  0.38
2009 Kefas B, Comeau L, Floyd DH, Seleverstov O, Godlewski J, Schmittgen T, Jiang J, diPierro CG, Li Y, Chiocca EA, Lee J, Fine H, Abounader R, Lawler S, Purow B. The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15161-8. PMID 19955368 DOI: 10.1523/Jneurosci.4966-09.2009  0.376
2009 Kaur B, Cripe TP, Chiocca EA. "Buy one get one free": armed viruses for the treatment of cancer cells and their microenvironment. Current Gene Therapy. 9: 341-55. PMID 19860649 DOI: 10.2174/156652309789753329  0.614
2009 Kim Y, Lawler S, Nowicki MO, Chiocca EA, Friedman A. A mathematical model for pattern formation of glioma cells outside the tumor spheroid core. Journal of Theoretical Biology. 260: 359-71. PMID 19596356 DOI: 10.1016/J.Jtbi.2009.06.025  0.385
2009 Asadi-Moghaddam K, Chiocca EA. Gene- and Viral-Based Therapies for Brain Tumors Neurotherapeutics. 6: 547-557. PMID 19560744 DOI: 10.1016/J.Nurt.2009.04.007  0.426
2009 Tanaka S, Shaikh IM, Chiocca EA, Saeki Y. The Gs-linked receptor GPR3 inhibits the proliferation of cerebellar granule cells during postnatal development. Plos One. 4: e5922. PMID 19526062 DOI: 10.1371/Journal.Pone.0005922  0.3
2009 Alvarez-Breckenridge C, Kaur B, Chiocca EA. Pharmacologic and chemical adjuvants in tumor virotherapy. Chemical Reviews. 109: 3125-40. PMID 19462957 DOI: 10.1021/Cr900048K  0.607
2009 Lawler S, Chiocca EA. Emerging functions of microRNAs in glioblastoma. Journal of Neuro-Oncology. 92: 297-306. PMID 19357957 DOI: 10.1007/S11060-009-9843-2  0.369
2009 Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC. Design and application of oncolytic HSV vectors for glioblastoma therapy. Expert Review of Neurotherapeutics. 9: 505-17. PMID 19344302 DOI: 10.1586/Ern.09.9  0.471
2009 Suzuki M, Kasai K, Ohtsuki A, Godlewski J, Nowicki MO, Chiocca EA, Saeki Y. ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression Molecular Therapy. 17: 707-715. PMID 19223864 DOI: 10.1038/Mt.2008.306  0.34
2009 Johnson J, Nowicki MO, Lee CH, Chiocca EA, Viapiano MS, Lawler SE, Lannutti JJ. Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopy. Tissue Engineering. Part C, Methods. 15: 531-40. PMID 19199562 DOI: 10.1089/Ten.Tec.2008.0486  0.338
2009 Hirschl RA, Wilson J, Miller B, Bergese S, Chiocca EA. The predictive value of low-field strength magnetic resonance imaging for intraoperative residual tumor detection: Clinical article Journal of Neurosurgery. 111: 252-257. PMID 19199455 DOI: 10.3171/2008.9.Jns08729  0.303
2009 Aghi MK, Chiocca EA. Phase Ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication Molecular Therapy. 17: 8-9. PMID 19116635 DOI: 10.1038/Mt.2008.275  0.324
2008 Chiocca EA, Smith KM, McKinney B, Palmer CA, Rosenfeld S, Lillehei K, Hamilton A, DeMasters BK, Judy K, Kirn D. A Phase I Trial of Ad.hIFN-β Gene Therapy for Glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 618-626. PMID 28178503 DOI: 10.1038/Sj.Mt.6300396  0.333
2008 Suzuki M, Chiocca EA, Saeki Y. Stable transgene expression from HSV amplicon vectors in the brain: Potential involvement of immunoregulatory signals Molecular Therapy. 16: 1727-1736. PMID 18728642 DOI: 10.1038/Mt.2008.175  0.364
2008 Nowicki MO, Dmitrieva N, Stein AM, Cutter JL, Godlewski J, Saeki Y, Nita M, Berens ME, Sander LM, Newton HB, Chiocca EA, Lawler S. Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3. Neuro-Oncology. 10: 690-9. PMID 18715951 DOI: 10.1215/15228517-2008-041  0.373
2008 Otsuki A, Patel A, Kasai K, Suzuki M, Kurozumi K, Chiocca EA, Saeki Y. Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses Molecular Therapy. 16: 1546-1555. PMID 18648350 DOI: 10.1038/Mt.2008.155  0.402
2008 Kurozumi K, Hardcastle J, Thakur R, Shroll J, Nowicki M, Otsuki A, Chiocca EA, Kaur B. Oncolytic HSV-1 infection of tumors induces angiogenesis and upregulates CYR61. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1382-91. PMID 18545226 DOI: 10.1038/Mt.2008.112  0.611
2008 Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, Hawkinson M, Lee J, Fine H, Chiocca EA, Lawler S, Purow B. microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Research. 68: 3566-72. PMID 18483236 DOI: 10.1158/0008-5472.Can-07-6639  0.312
2008 Currier MA, Gillespie RA, Sawtell NM, Mahller YY, Stroup G, Collins MH, Kambara H, Chiocca EA, Cripe TP. Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 879-85. PMID 18388918 DOI: 10.1038/Mt.2008.49  0.359
2008 Aghi M, Visted T, Depinho RA, Chiocca EA. Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16. Oncogene. 27: 4249-54. PMID 18345032 DOI: 10.1038/onc.2008.53  0.331
2007 Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg FH, Weissleder R, Carson W, Chiocca EA, Kaur B. Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. Journal of the National Cancer Institute. 99: 1768-81. PMID 18042934 DOI: 10.1093/Jnci/Djm229  0.572
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Stemmer-Rachamimov AO, Rachamimov AS, ... ... Chiocca EA, et al. Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Research. 67: 9398-406. PMID 17909049 DOI: 10.1158/0008-5472.Can-07-1063  0.552
2007 Stein AM, Nowicki MO, Demuth T, Berens ME, Lawler SE, Chiocca EA, Sander LM. Estimating the cell density and invasive radius of three-dimensional glioblastoma tumor spheroids grown in vitro. Applied Optics. 46: 5110-8. PMID 17676121 DOI: 10.1364/Ao.46.005110  0.341
2007 Suzuki M, Chiocca EA, Saeki Y. Early STAT1 activation after systemic delivery of HSV amplicon vectors suppresses transcription of the vector-encoded transgene. Molecular Therapy. 15: 2017-2026. PMID 17653098 DOI: 10.1038/Sj.Mt.6300273  0.303
2007 Chiocca EA, Schwartzbaum JA. Gliomas and venous thromboembolism: how common? Journal of Neurosurgery. 106: 599-600; discussion . PMID 17432709 DOI: 10.3171/Jns.2007.106.4.599  0.3
2007 Hardcastle J, Kurozumi K, Chiocca EA, Kaur B. Oncolytic viruses driven by tumor-specific promoters. Current Cancer Drug Targets. 7: 181-9. PMID 17346110 DOI: 10.2174/156800907780058880  0.595
2007 Kaur B, Chiocca EA. Personalizing oncolytic virotherapy? Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 6-7. PMID 17164767 DOI: 10.1038/Sj.Mt.6300056  0.545
2006 Kaur B, Chiocca EA. Oncolytic viruses: extreme treatment for an extreme disease. Future Microbiology. 1: 351-3. PMID 17661625 DOI: 10.2217/17460913.1.4.351  0.558
2006 Thoman WJ, Ammirati M, Caragine LP, McGregor JM, Sarkar A, Chiocca EA. Brain tumor imaging and surgical management: the neurosurgeon's perspective. Topics in Magnetic Resonance Imaging. 17: 121-126. PMID 17198228 DOI: 10.1097/Rmr.0B013E31802F5De8  0.322
2006 Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA. Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 779-88. PMID 16996314 DOI: 10.1016/J.Ymthe.2006.08.008  0.56
2006 Aghi M, Cohen KS, Klein RJ, Scadden DT, Chiocca EA. Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes. Cancer Research. 66: 9054-64. PMID 16982747 DOI: 10.1158/0008-5472.Can-05-3759  0.398
2006 Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 12873-8. PMID 16908838 DOI: 10.1073/Pnas.0605496103  0.58
2006 Yamamoto S, Deckter LA, Kasai K, Chiocca EA, Saeki Y. Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors. Gene Therapy. 13: 1731-6. PMID 16871231 DOI: 10.1038/sj.gt.3302831  0.3
2006 Cutter JL, Kurozumi K, Chiocca EA, Kaur B. Gene therapeutics: the future of brain tumor therapy? Expert Review of Anticancer Therapy. 6: 1053-64. PMID 16831077 DOI: 10.1586/14737140.6.7.1053  0.605
2006 Aghi M, Chiocca EA. Gene therapy for glioblastoma. Neurosurgical Focus. 20: E18. PMID 16709023  0.317
2006 Friedman A, Tian JP, Fulci G, Chiocca EA, Wang J. Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity. Cancer Research. 66: 2314-9. PMID 16489036 DOI: 10.1158/0008-5472.Can-05-2661  0.433
2006 Terada K, Wakimoto H, Tyminski E, Chiocca EA, Saeki Y. Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models. Gene Therapy. 13: 705-14. PMID 16421599 DOI: 10.1038/sj.gt.3302717  0.313
2006 Otsuki A, Patel A, Camilli S, Kasai K, Tanaka S, Chiocca EA, Saeki Y. 434. Oncolytic Virotherapy Using the HSV Mutant rQNestin34.5 towards CD133+ Brain Tumor Stem Cells Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.500  0.4
2005 Kambara H, Saeki Y, Chiocca EA. Cyclophosphamide Allows for In vivo Dose Reduction of a Potent Oncolytic Virus Cancer Research. 65: 11255-11258. PMID 16357128 DOI: 10.1158/0008-5472.Can-05-2278  0.374
2005 Lamfers MLM, Gianni D, Tung CH, Idema S, Schagen FHE, Carette JE, Quax PHA, Beusechem VWV, Vandertop WP, Dirven CMF, Chiocca EA, Gerritsen WR. Tissue Inhibitor of Metalloproteinase-3 Expression from an Oncolytic Adenovirus Inhibits Matrix Metalloproteinase Activity In vivo without Affecting Antitumor Efficacy in Malignant Glioma Cancer Research. 65: 9398-9405. PMID 16230403 DOI: 10.1158/0008-5472.Can-04-4264  0.43
2005 Aghi M, Chiocca EA. Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors. Molecular Therapy. 12: 994-1005. PMID 16137927 DOI: 10.1016/J.Ymthe.2005.07.693  0.369
2005 Tyminski E, Leroy S, Terada K, Finkelstein DM, Hyatt JL, Danks MK, Potter PM, Saeki Y, Chiocca EA. Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan. Cancer Research. 65: 6850-7. PMID 16061668 DOI: 10.1158/0008-5472.Can-05-0154  0.44
2005 Kambara H, Okano H, Chiocca EA, Saeki Y. An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor. Cancer Research. 65: 2832-9. PMID 15805284 DOI: 10.1158/0008-5472.Can-04-3227  0.452
2004 Chiocca EA, Broaddus WC, Gillies GT, Visted T, Lamfers ML. Neurosurgical delivery of chemotherapeutics, targeted toxins, genetic and viral therapies in neuro-oncology. Journal of Neuro-Oncology. 69: 101-17. PMID 15527083 DOI: 10.1023/B:Neon.0000041874.02554.B3  0.32
2004 Chiocca EA, Abbed KM, Tatter S, Louis DN, Hochberg FH, Barker F, Kracher J, Grossman SA, Fisher JD, Carson K, Rosenblum M, Mikkelsen T, Olson J, Markert J, Rosenfeld S, et al. A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 958-66. PMID 15509513 DOI: 10.1016/J.Ymthe.2004.07.021  0.523
2004 Nestler U, Wakimoto H, Siller-Lopez F, Aguilar LK, Chakravarti A, Muzikansky A, Stemmer-Rachamimov A, Chiocca EA, Aguilar-Cordova E, Hochberg FH. The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects Journal of Neuro-Oncology. 67: 177-188. PMID 15072465 DOI: 10.1023/B:Neon.0000021897.53969.Ca  0.319
2004 Post DE, Fulci G, Chiocca EA, Van Meir EG. Replicative oncolytic herpes simplex viruses in combination cancer therapies. Current Gene Therapy. 4: 41-51. PMID 15032613 DOI: 10.2174/1566523044577988  0.442
2004 Wakimoto H, Fulci G, Tyminski E, Chiocca EA. Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide’s enhancement of viral oncolysis Gene Therapy. 11: 214-223. PMID 14712306 DOI: 10.1038/Sj.Gt.3302143  0.447
2004 Packard SD, Mandeville JB, Ichikawa T, Ikeda K, Terada K, Niloff S, Chiocca EA, Rosen BR, Marota JJ. Functional response of tumor vasculature to PaCO2: determination of total and microvascular blood volume by MRI. Neoplasia (New York, N.Y.). 5: 330-8. PMID 14511404 DOI: 10.1016/S1476-5586(03)80026-X  0.358
2004 Ino Y, Saeki Y, Chiocca EA, Todo T. 804. Expression of Green Fluorescent Protein Modifies the Antitumor Effect of Oncolytic HSV-1 Vectors Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.843  0.44
2004 Kambara H, Okano H, Chiocca EA, Saeki Y. 624. Effect of an Oncolytic HSV Mutant Expressing ICP34.5 under Control of a Nestin Promoter for Brain Tumor Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.548  0.47
2003 Chiocca EA, Aghi M, Fulci G. Viral therapy for glioblastoma. Cancer Journal. 9: 167-179. PMID 12952302 DOI: 10.1097/00130404-200305000-00005  0.395
2003 Chiocca EA. Gene Therapy: A Primer for Neurosurgeons Neurosurgery. 53: 364-373. PMID 12925253 DOI: 10.1227/01.Neu.0000073532.05714.2B  0.328
2003 Kubo S, Saeki Y, Chiocca EA, Mitani K. An HSV amplicon-based helper system for helper-dependent adenoviral vectors. Biochemical and Biophysical Research Communications. 307: 826-830. PMID 12878185 DOI: 10.1016/S0006-291X(03)01256-7  0.326
2003 Hampl JA, Camp SM, Mydlarz WK, Hampl M, Ichikawa T, Chiocca EA, Louis DN, Sena-Esteves M, Breakefield XO. Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors. Human Gene Therapy. 14: 611-26. PMID 12804144 DOI: 10.1089/104303403321618137  0.451
2003 Wakimoto H, Johnson PR, Knipe DM, Chiocca EA. Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells Gene Therapy. 10: 983-990. PMID 12756419 DOI: 10.1038/Sj.Gt.3302038  0.312
2003 Wade-Martins R, Saeki Y, Chiocca EA. Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells. Molecular Therapy. 7: 604-612. PMID 12718903 DOI: 10.1016/S1525-0016(03)00060-1  0.319
2003 Fulci G, Chiocca EA. Oncolytic viruses for the therapy of brain tumors and other solid malignancies: a review. Frontiers in Bioscience : a Journal and Virtual Library. 8: e346-60. PMID 12700108 DOI: 10.2741/976  0.358
2002 Rabinov JD, Lee PL, Barker FG, Louis DN, Harsh GR, Cosgrove GR, Chiocca EA, Thornton AF, Loeffler JS, Henson JW, Gonzalez RG. In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience. Radiology. 225: 871-9. PMID 12461273 DOI: 10.1148/Radiol.2253010997  0.341
2002 Nakamura H, Kasuya H, Mullen JT, Yoon SS, Pawlik TM, Chandrasekhar S, Donahue JM, Chiocca EA, Chung RY, Tanabe KK. Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5. The Journal of Clinical Investigation. 109: 871-82. PMID 11927614 DOI: 10.1172/Jci10623  0.36
2002 Abe T, Wakimoto H, Bookstein R, Maneval DC, Chiocca EA, Basilion JP. Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumors. Cancer Gene Therapy. 9: 228-235. PMID 11896438 DOI: 10.1038/Sj.Cgt.7700437  0.42
2002 Chiocca EA. Guided genes for tumor warfare. Nature Biotechnology. 20: 235-236. PMID 11875420 DOI: 10.1038/Nbt0302-235  0.404
2002 Wakimoto H, Ikeda K, Abe T, Ichikawa T, Hochberg FH, Ezekowitz RAB, Pasternack MS, Chiocca EA. The complement response against an oncolytic virus is species-specific in its activation pathways. Molecular Therapy. 5: 275-282. PMID 11863417 DOI: 10.1006/Mthe.2002.0547  0.391
2001 Saeki Y, Fraefel C, Ichikawa T, Breakefield XO, Chiocca EA. Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 591-601. PMID 11319922 DOI: 10.1006/Mthe.2001.0294  0.309
2000 Chiocca EA, Smith ER. Oncolytic viruses as novel anticancer agents: turning one scourge against another. Expert Opinion On Investigational Drugs. 9: 311-327. PMID 11060679 DOI: 10.1517/13543784.9.2.311  0.362
2000 Spear MA, Sun F, Eling DJ, Gilpin E, Kipps TJ, Chiocca EA, Bouvet M. Cytotoxicity, apoptosis, and viral replication in tumor cells treated with oncolytic ribonucleotide reductase-defective herpes simplex type 1 virus (hrR3) combined with ionizing radiation. Cancer Gene Therapy. 7: 1051-9. PMID 10917208 DOI: 10.1038/Sj.Cgt.7700208  0.41
2000 Harsh GR, Deisboeck TS, Louis DN, Hilton J, Colvin M, Silver JS, Qureshi NH, Kracher J, Finkelstein D, Chiocca EA, Hochberg FH. Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study. Journal of Neurosurgery. 92: 804-11. PMID 10794295 DOI: 10.3171/Jns.2000.92.5.0804  0.354
2000 Ikeda K, Wakimoto H, Ichikawa T, Jhung S, Hochberg FH, Louis DN, Chiocca EA. Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant. Journal of Virology. 74: 4765-75. PMID 10775615 DOI: 10.1128/Jvi.74.10.4765-4775.2000  0.46
2000 Qureshi NH, Chiocca EA. A review of gene therapy for the treatment of central nervous system tumors. Critical Reviews in Oncogenesis. 10: 261-74. PMID 10654926  0.335
2000 Basilion JP, Ichikawa T, Chiocca EA. Gene therapy of brain tumors: problems presented by physiological barriers Neurosurgical Focus. 8: 1-7. DOI: 10.3171/Foc.2000.8.4.3  0.359
2000 Nakamura H, Yoon SS, Pawlik TM, Mullen JT, Chandrasekhar S, Chiocca EA, Chung RY, Tanabe KK. Mechanism of specific infection and destruction of diffuse liver metastases by a replication-competent herpes simplex virus Journal of the American College of Surgeons. 191. DOI: 10.1016/S1072-7515(00)00589-5  0.388
1999 Sena-Esteves M, Saeki Y, Camp SM, Chiocca EA, Breakefield XO. Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons. Journal of Virology. 73: 10426-39. PMID 10559361 DOI: 10.1128/Jvi.73.12.10426-10439.1999  0.353
1999 Aghi M, Chou TC, Suling K, Breakefield XO, Chiocca EA. Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Research. 59: 3861-5. PMID 10463570  0.314
1999 Chung RY, Saeki Y, Chiocca EA. B-myb Promoter Retargeting of Herpes Simplex Virus γ34.5 Gene-Mediated Virulence toward Tumor and Cycling Cells Journal of Virology. 73: 7556-7564. PMID 10438845 DOI: 10.1128/Jvi.73.9.7556-7564.1999  0.378
1999 Ikeda K, Ichikawa T, Wakimoto H, Silver JS, Deisboeck TS, Finkelstein D, Harsh GR, Louis DN, Bartus RT, Hochberg FH, Chiocca EA. Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nature Medicine. 5: 881-7. PMID 10426310 DOI: 10.1038/11320  0.425
1999 Barnett FH, Rainov NG, Ikeda K, Schuback DE, Elliott P, Kramm CM, Chase M, Qureshi NH, Harsh G, Chiocca EA, Breakefield XO. Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7. Cancer Gene Therapy. 6: 14-20. PMID 10078959 DOI: 10.1038/Sj.Cgt.7700003  0.449
1999 Chung R, Chiocca EA. Targeting Gamma34.5-mediated Herpes Virulence for Tumor Therapy Neurosurgery. 45: 729-729. DOI: 10.1097/00006123-199909000-00185  0.382
1998 Rainov NG, Sena-Esteves M, Fraefel C, Dobberstein KU, Chiocca EA, Breakefield XO. A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma. Advances in Experimental Medicine and Biology. 451: 393-403. PMID 10026902 DOI: 10.1007/978-1-4615-5357-1_61  0.319
1998 Rainov NG, Dobberstein KU, Sena-Esteves M, Herrlinger U, Kramm CM, Philpot RM, Hilton J, Chiocca EA, Breakefield XO. New prodrug activation gene therapy for cancer using cytochrome P450 4B1 and 2-aminoanthracene/4-ipomeanol. Human Gene Therapy. 9: 1261-73. PMID 9650611 DOI: 10.1089/Hum.1998.9.9-1261  0.439
1998 Chung RY, Chiocca EA. Gene therapy for tumors of the central nervous system. Surgical Oncology Clinics of North America. 7: 589-602. PMID 9624219  0.316
1998 Rainov NG, Dobberstein KU, Heidecke V, Dorant U, Chase M, Kramm CM, Chiocca EA, Breakefield XO. Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector. Cancer Gene Therapy. 5: 158-62. PMID 9622099  0.309
1998 Chase M, Chung RY, Chiocca EA. An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy. Nature Biotechnology. 16: 444-8. PMID 9592392 DOI: 10.1038/nbt0598-444  0.345
1998 Wei MX, Li F, Ono Y, Gauldie J, Chiocca EA. Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin-4 gene Journal of Neurovirology. 4: 237-241. PMID 9584960 DOI: 10.3109/13550289809114523  0.39
1998 Husain N, Chiocca EA, Rainov N, Louis DN, Zervas NT. Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines. Acta Neuropathologica. 95: 287-90. PMID 9542594 DOI: 10.1007/S004010050799  0.303
1998 Aghi M, Kramm CM, Chou TC, Breakefield XO, Chiocca EA. Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. Journal of the National Cancer Institute. 90: 370-80. PMID 9498487 DOI: 10.1093/Jnci/90.5.370  0.337
1998 Chung RY, Chiocca EA. Gene therapy for tumors of the central nervous system. Surgical Oncology Clinics of North America. 7: 589-602. DOI: 10.1016/S1055-3207(18)30262-X  0.428
1997 Tang G, Chiocca EA. Gene transfer and delivery in central nervous system disease. Neurosurgical Focus. 3. PMID 15104414 DOI: 10.3171/Foc.1997.3.3.5  0.355
1997 Kramm CM, Chase M, Herrlinger U, Jacobs A, Pechan PA, Rainov NG, Sena-Esteves M, Aghi M, Barnett FH, Chiocca EA, Breakefield XO. Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy. Human Gene Therapy. 8: 2057-68. PMID 9414254 DOI: 10.1089/hum.1997.8.17-2057  0.316
1997 Ono Y, Ikeda K, Wei MX, Harsh IV GR, Tamiya T, Chiocca EA. Regression of experimental brain tumors with 6-thioxanthine and Escherichia coli pgt gene therapy Human Gene Therapy. 8: 2043-2055. PMID 9414253 DOI: 10.1089/Hum.1997.8.17-2043  0.425
1997 Carroll NM, Chase M, Chiocca EA, Tanabe KK. The Effect of Ganciclovir on Herpes Simplex Virus-Mediated Oncolysis Journal of Surgical Research. 69: 413-417. PMID 9224416 DOI: 10.1006/Jsre.1997.5089  0.387
1996 Pechan PA, Fotaki M, Thompson RL, Dunn R, Chase M, Chiocca EA, Breakefield XO. A novel 'piggyback' packaging system for herpes simplex virus amplicon vectors. Human Gene Therapy. 7: 2003-13. PMID 8930661 DOI: 10.1089/Hum.1996.7.16-2003  0.365
1996 Kramm CM, Rainov NG, Sena-Esteves M, Barnett FH, Chase M, Herrlinger U, Pechan PA, Chiocca EA, Breakefield XO. Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment. Human Gene Therapy. 7: 1989-94. PMID 8930659 DOI: 10.1089/Hum.1996.7.16-1989  0.43
1996 Kramm CM, Rainov NG, Sena-Esteves M, Chase M, Pechan PA, Chiocca EA, Breakefield XO. Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors. Human Gene Therapy. 7: 291-300. PMID 8835217 DOI: 10.1089/Hum.1996.7.3-291  0.44
1995 Kramm CM, Sena-Esteves M, Barnett FH, Rainov NG, Schuback DE, Yu JS, Pechan PA, Paulus W, Chiocca EA, Breakefield XO. Gene therapy for brain tumors. Brain Pathology (Zurich, Switzerland). 5: 345-81. PMID 8974620 DOI: 10.1111/J.1750-3639.1995.Tb00615.X  0.451
1995 Rainov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO. Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Human Gene Therapy. 6: 1543-52. PMID 8664379 DOI: 10.1089/Hum.1995.6.12-1543  0.394
1995 Tamiya T, Wei MX, Chase M, Ono Y, Lee F, Breakefield XO, Chiocca EA. Transgene inheritance and retroviral infection contribute to the efficiency of gene expression in solid tumors inoculated with retroviral vector producer cells. Gene Therapy. 2: 531-8. PMID 8593603  0.301
1995 Wei MX, Tamiya T, Hurford RK, Boviatsis EJ, Tepper RI, Chiocca EA. Enhancement of interleukin-4-mediated tumor regression in athymic mice by in situ retroviral gene transfer. Human Gene Therapy. 6: 437-443. PMID 7612701 DOI: 10.1089/Hum.1995.6.4-437  0.344
1994 Boviatsis EJ, Chase M, Wei MX, Tamiya T, Hurford RK, Kowall NW, Tepper RI, Breakefield XO, Chiocca EA. Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. Human Gene Therapy. 5: 183-91. PMID 8186298 DOI: 10.1089/Hum.1994.5.2-183  0.418
1994 Wei MX, Tamiya T, Chase M, Boviatsis EJ, Chang TK, Kowall NW, Hochberg FH, Waxman DJ, Breakefield XO, Chiocca EA. Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene. Human Gene Therapy. 5: 969-78. PMID 7948146 DOI: 10.1089/Hum.1994.5.8-969  0.398
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