Year |
Citation |
Score |
2023 |
Leggio L, Hendershot CS, Farokhnia M, Fink-Jensen A, Klausen MK, Schacht JP, Simmons WK. GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders. Nature Medicine. PMID 38001271 DOI: 10.1038/s41591-023-02634-8 |
0.431 |
|
2023 |
Crozier ME, Farokhnia M, Persky S, Leggio L, Curtis B. Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving. Bmj Mental Health. 26. PMID 37993282 DOI: 10.1136/bmjment-2023-300852 |
0.528 |
|
2023 |
Singal AK, Leggio L, DiMartini A. Alcohol use disorder in alcohol-associated liver disease: Two sides of the same coin. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 37934047 DOI: 10.1097/LVT.0000000000000296 |
0.501 |
|
2023 |
Leggio L, Leko A, Gregory-Flores A, Marchette R, Gomez J, Vendruscolo J, Repunte-Canonigo V, Chuong V, Deschaine S, Whiting K, Jackson S, Cornejo M, Perello M, You ZB, Eckhaus M, et al. Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Research Square. PMID 37886546 DOI: 10.21203/rs.3.rs-3236045/v1 |
0.664 |
|
2023 |
Diaz LA, Winder GS, Leggio L, Bajaj JS, Bataller R, Arab JP. New insights into the molecular basis of alcohol abstinence and relapse in alcohol-associated liver disease. Hepatology (Baltimore, Md.). PMID 37862466 DOI: 10.1097/HEP.0000000000000645 |
0.458 |
|
2023 |
Pince CL, Whiting KE, Wang T, Lékó AH, Farinelli LA, Cooper D, Farokhnia M, Vendruscolo LF, Leggio L. Role of aldosterone and mineralocorticoid receptor (MR) in addiction: A scoping review. Neuroscience and Biobehavioral Reviews. 154: 105427. PMID 37858908 DOI: 10.1016/j.neubiorev.2023.105427 |
0.314 |
|
2023 |
Unlu H, Macaron MM, Ayraler Taner H, Kaba D, Akin Sari B, Schneekloth TD, Leggio L, Abulseoud OA. Sex difference in alcohol withdrawal syndrome: a scoping review of clinical studies. Frontiers in Psychiatry. 14: 1266424. PMID 37810604 DOI: 10.3389/fpsyt.2023.1266424 |
0.408 |
|
2023 |
Vendruscolo LF, Lee MR, Leggio L. Alcohol Use Disorder and Posttraumatic Stress Disorder: A Relationship Unbonded by Oxytocin Blockade. Biological Psychiatry. 94: 189-190. PMID 37437989 DOI: 10.1016/j.biopsych.2023.04.012 |
0.368 |
|
2023 |
Richardson RS, Sulima A, Rice KC, Kucharczk JA, Janda KD, Nisbett KE, Koob GF, Vendruscolo LF, Leggio L. Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice. Neuropharmacology. 109643. PMID 37369277 DOI: 10.1016/j.neuropharm.2023.109643 |
0.584 |
|
2023 |
Haass-Koffler CL, Magill M, Cannella N, Brown JC, Aoun EG, Cioe PA, Sinha R, Swift RM, Ciccocioppo R, Leggio L. Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Addiction Biology. 28: e13288. PMID 37369125 DOI: 10.1111/adb.13288 |
0.55 |
|
2023 |
Chuong V, Farokhnia M, Khom S, Pince CL, Elvig SK, Vlkolinsky R, Marchette RC, Koob GF, Roberto M, Vendruscolo LF, Leggio L. The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission. Jci Insight. PMID 37192005 DOI: 10.1172/jci.insight.170671 |
0.74 |
|
2023 |
Battista JT, Piacentino D, Schwandt ML, Lee MR, Faulkner ML, Farokhnia M, Leggio L. Investigating the relationship between early life adversity, inflammation and alcohol use. Addiction Biology. 28: e13274. PMID 37186442 DOI: 10.1111/adb.13274 |
0.639 |
|
2023 |
Lékó AH, Ray LA, Leggio L. The vicious cycle between (neuro)inflammation and alcohol use disorder: An opportunity to develop new medications? Alcoholism, Clinical and Experimental Research. PMID 36882163 DOI: 10.1111/acer.15049 |
0.415 |
|
2023 |
Farokhnia M, Wang T, Jourdan T, Godlewski G, Farinelli LA, Kunos G, Leggio L. A human laboratory study on the link between alcohol administration and circulating fibroblast growth factor 21 (FGF21) in individuals with alcohol use disorder. Drug and Alcohol Dependence. 245: 109809. PMID 36822122 DOI: 10.1016/j.drugalcdep.2023.109809 |
0.547 |
|
2023 |
Haass-Koffler CL, Magill M, Cannella N, Brown JC, Aoun EG, Cioe PA, Sinha R, Swift RM, Ciccocioppo R, Leggio L. Mifepristone as a pharmacological intervention for stress-Induced alcohol craving: a translational crossover randomized trial. Medrxiv : the Preprint Server For Health Sciences. PMID 36711869 DOI: 10.1101/2023.01.02.23284122 |
0.539 |
|
2023 |
Deschaine SL, Hedegaard MA, Pince CL, Farokhnia M, Moose JE, Stock IA, Adusumalli S, Akhlaghi F, Hougland JL, Sulima A, Rice KC, Koob GF, Vendruscolo L, Holst B, Leggio L. . The Journal of Pharmacology and Experimental Therapeutics. PMID 36631279 DOI: 10.1124/jpet.122.001393 |
0.348 |
|
2022 |
MacKillop J, Agabio R, Feldstein Ewing SW, Heilig M, Kelly JF, Leggio L, Lingford-Hughes A, Palmer AA, Parry CD, Ray L, Rehm J. Hazardous drinking and alcohol use disorders. Nature Reviews. Disease Primers. 8: 80. PMID 36550121 DOI: 10.1038/s41572-022-00406-1 |
0.457 |
|
2022 |
Kharbanda KK, Farokhnia M, Deschaine SL, Bhargava R, Rodriguez-Flores M, Casey CA, Goldstone AP, Jerlhag E, Leggio L, Rasineni K. Role of the ghrelin system in alcohol use disorder and alcohol-associated liver disease: A narrative review. Alcoholism, Clinical and Experimental Research. PMID 36316764 DOI: 10.1111/acer.14967 |
0.513 |
|
2022 |
Elfeki MA, Abdallah MA, Leggio L, Singal AK. Simultaneous Management of Alcohol Use Disorder and of Liver Disease: A Systematic Review and Meta-analysis. Journal of Addiction Medicine. PMID 36259647 DOI: 10.1097/ADM.0000000000001084 |
0.314 |
|
2022 |
Farokhnia M, Rentsch CT, Chuong V, McGinn MA, Elvig SK, Douglass EA, Gonzalez LA, Sanfilippo JE, Marchette RCN, Tunstall BJ, Fiellin DA, Koob GF, Justice AC, Leggio L, Vendruscolo LF. Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies. Molecular Psychiatry. PMID 36123420 DOI: 10.1038/s41380-022-01736-y |
0.747 |
|
2022 |
Farokhnia M, Browning BD, Crozier ME, Sun H, Akhlaghi F, Leggio L. The glucagon-like peptide-1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post-mortem brain study. Addiction Biology. 27: e13211. PMID 36001436 DOI: 10.1111/adb.13211 |
0.518 |
|
2022 |
Orellana E, Horvath N, Farokhnia M, Leggio L, Hajnal A. Changes in Plasma Ghrelin Levels Following Surgical and Non-Surgical Weight-Loss in Female Rats Predict Alcohol Use. Brain Research Bulletin. PMID 35901985 DOI: 10.1016/j.brainresbull.2022.07.019 |
0.458 |
|
2022 |
Singal AK, DiMartini A, Leggio L, Arab JP, Kuo YF, Shah VH. Identifying Alcohol Use Disorder in Patients With Cirrhosis Reduces 30-Days Readmission Rate. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 35544033 DOI: 10.1093/alcalc/agac015 |
0.48 |
|
2022 |
Kirkland AE, Browning BD, Green R, Leggio L, Meyerhoff DJ, Squeglia LM. Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies. Molecular Psychiatry. PMID 35508628 DOI: 10.1038/s41380-022-01594-8 |
0.435 |
|
2022 |
Wang T, Farokhnia M, Leggio L. FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment? Cell Reports. Medicine. 3: 100578. PMID 35492877 DOI: 10.1016/j.xcrm.2022.100578 |
0.523 |
|
2022 |
Leggio L, Mellinger JL. Alcohol use disorder in community management of chronic liver diseases. Hepatology (Baltimore, Md.). PMID 35434815 DOI: 10.1002/hep.32531 |
0.481 |
|
2022 |
Varodayan FP, Patel RR, Matzeu A, Wolfe SA, Curley DE, Khom S, Gandhi PJ, Rodriguez L, Bajo M, D'Ambrosio S, Sun H, Kerr TM, Gonzales RA, Leggio L, Natividad LA, et al. The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder. Biological Psychiatry. PMID 35430085 DOI: 10.1016/j.biopsych.2022.02.006 |
0.444 |
|
2022 |
Mirijello A, Sestito L, Lauria C, Tarli C, Vassallo GA, Antonelli M, d'Angelo C, Ferrulli A, Crea F, Cossari A, Leggio L, De Cosmo S, Gasbarrini A, Addolorato G. Echocardiographic markers of early alcoholic cardiomyopathy: Six-month longitudinal study in heavy drinking patients. European Journal of Internal Medicine. PMID 35418346 DOI: 10.1016/j.ejim.2022.04.005 |
0.529 |
|
2022 |
DiMartini AF, Leggio L, Singal AK. Barriers to the management of alcohol use disorder and alcohol-associated liver disease: strategies to implement integrated care models. The Lancet. Gastroenterology & Hepatology. 7: 186-195. PMID 35026172 DOI: 10.1016/S2468-1253(21)00191-6 |
0.498 |
|
2021 |
Harris JC, Leggio L, Farokhnia M. Blood Biomarkers of Alcohol Use: A Scoping Review. Current Addiction Reports. 8: 500-508. PMID 37274945 DOI: 10.1007/s40429-021-00402-7 |
0.498 |
|
2021 |
Piacentino D, Grant-Beurmann S, Vizioli C, Li X, Moore CF, Ruiz-Rodado V, Lee MR, Joseph PV, Fraser CM, Weerts EM, Leggio L. Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking. Translational Psychiatry. 11: 609. PMID 34853299 DOI: 10.1038/s41398-021-01728-6 |
0.723 |
|
2021 |
Traccis F, Presciuttini R, Pani PP, Sinclair JMA, Leggio L, Agabio R. Alcohol-medication interactions: A systematic review and meta-analysis of placebo-controlled trials. Neuroscience and Biobehavioral Reviews. 132: 519-541. PMID 34826511 DOI: 10.1016/j.neubiorev.2021.11.019 |
0.45 |
|
2021 |
Haass-Koffler CL, Perciballi R, Magill M, Loche A, Cacciaglia R, Leggio L, Swift RM. An inpatient human laboratory study assessing the safety and tolerability, pharmacokinetics, and biobehavioral effect of GET 73 when co-administered with alcohol in individuals with alcohol use disorder. Psychopharmacology. PMID 34731268 DOI: 10.1007/s00213-021-06008-1 |
0.509 |
|
2021 |
Agabio R, Leggio L. Thiamine administration to patients with alcohol use disorder: why not? The American Journal of Drug and Alcohol Abuse. 47: 651-654. PMID 34710331 DOI: 10.1080/00952990.2021.1978474 |
0.479 |
|
2021 |
Sulima A, Akhlaghi F, Leggio L, Rice KC. Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457. Bioorganic & Medicinal Chemistry. 50: 116465. PMID 34662828 DOI: 10.1016/j.bmc.2021.116465 |
0.368 |
|
2021 |
Kärkkäinen O, Farokhnia M, Klåvus A, Auriola S, Lehtonen M, Deschaine SL, Piacentino D, Abshire KM, Jackson SN, Leggio L. Effect of intravenous ghrelin administration, combined with alcohol, on circulating metabolome in heavy drinking individuals with alcohol use disorder. Alcoholism, Clinical and Experimental Research. PMID 34590334 DOI: 10.1111/acer.14719 |
0.579 |
|
2021 |
Goodyear K, Vasaturo-Kolodner TR, Kenna GA, Swift RM, Leggio L, Haass-Koffler CL. Alcohol-related changes in behaviors and characteristics from the baseline to the randomization session for treatment and non-treatment seeking participants with alcohol use disorder. The American Journal of Drug and Alcohol Abuse. 47: 760-768. PMID 34582281 DOI: 10.1080/00952990.2021.1961799 |
0.388 |
|
2021 |
Browning BD, Schwandt ML, Farokhnia M, Deschaine SL, Hodgkinson CA, Leggio L. Leptin Gene and Leptin Receptor Gene Polymorphisms in Alcohol Use Disorder: Findings Related to Psychopathology. Frontiers in Psychiatry. 12: 723059. PMID 34421692 DOI: 10.3389/fpsyt.2021.723059 |
0.434 |
|
2021 |
Scherrer B, Guiraud J, Addolorato G, Aubin HJ, de Bejczy A, Benyamina A, van den Brink W, Caputo F, Dematteis M, Goudriaan AE, Gual A, Kiefer F, Leggio L, Lesch OM, Maremmani I, et al. Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta-regression analysis to develop an enrichment strategy. Alcoholism, Clinical and Experimental Research. PMID 34418121 DOI: 10.1111/acer.14670 |
0.346 |
|
2021 |
Leggio L, Litten RZ. The GABA-B receptor agonist baclofen helps patients with alcohol use disorder: why these findings matter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34400781 DOI: 10.1038/s41386-021-01142-y |
0.367 |
|
2021 |
Palzes VA, Farokhnia M, Kline-Simon AH, Elson J, Sterling S, Leggio L, Weisner C, Chi FW. Effectiveness of spironolactone dispensation in reducing weekly alcohol use: a retrospective high-dimensional propensity score-matched cohort study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34341493 DOI: 10.1038/s41386-021-01117-z |
0.494 |
|
2021 |
Farokhnia M, Murphy G, Weinstein SJ, Shah NN, Parisi D, Albanes D, Leggio L. A population-based investigation of the association between alcohol intake and serum total ghrelin concentrations among cigarette-smoking, non-alcohol-dependent male individuals. Drug and Alcohol Dependence. 226: 108835. PMID 34214881 DOI: 10.1016/j.drugalcdep.2021.108835 |
0.549 |
|
2021 |
Harris JC, Mereish EH, Faulkner ML, Assari S, Choi K, Leggio L, Farokhnia M. Racial Differences in the Association Between Alcohol Drinking and Cigarette Smoking: Preliminary Findings From an Alcohol Research Program. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 34086845 DOI: 10.1093/alcalc/agab038 |
0.623 |
|
2021 |
Lee MR, Abshire KM, Farokhnia M, Akhlaghi F, Leggio L. Effect of oral alcohol administration on plasma cytokine concentrations in heavy drinking individuals. Drug and Alcohol Dependence. 225: 108771. PMID 34052691 DOI: 10.1016/j.drugalcdep.2021.108771 |
0.49 |
|
2021 |
Deschaine SL, Farokhnia M, Gregory-Flores A, Zallar LJ, You ZB, Sun H, Harvey DM, Marchette RCN, Tunstall BJ, Mani BK, Moose JE, Lee MR, Gardner E, Akhlaghi F, Roberto M, ... ... Leggio L, et al. A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data. Addiction Biology. e13033. PMID 33908131 DOI: 10.1111/adb.13033 |
0.576 |
|
2021 |
Faulkner ML, Momenan R, Leggio L. A neuroimaging investigation into the role of peripheral metabolic biomarkers in the anticipation of reward in alcohol use. Drug and Alcohol Dependence. 221: 108638. PMID 33667782 DOI: 10.1016/j.drugalcdep.2021.108638 |
0.681 |
|
2021 |
Farinelli LA, Piacentino D, Browning BD, Brewer BB, Leggio L. Cardiovascular Consequences of Excessive Alcohol Drinking via Electrocardiogram: A Systematic Review. Journal of Addictions Nursing. 32: 39-45. PMID 33646717 DOI: 10.1097/JAN.0000000000000384 |
0.51 |
|
2021 |
Agarwal K, Manza P, Leggio L, Livinski AA, Volkow ND, Joseph PV. Sensory Cue Reactivity: Sensitization in Alcohol Use Disorder and Obesity. Neuroscience and Biobehavioral Reviews. PMID 33587959 DOI: 10.1016/j.neubiorev.2021.02.014 |
0.75 |
|
2021 |
Farokhnia M, Abshire KM, Hammer A, Deschaine SL, Saravanakumar A, Cobbina E, You ZB, Haass-Koffler CL, Lee MR, Akhlaghi F, Leggio L. Neuroendocrine response to exogenous ghrelin administration, combined with alcohol, in heavy-drinking individuals: Findings from a randomized, double-blind, placebo-controlled human laboratory study. The International Journal of Neuropsychopharmacology. PMID 33560411 DOI: 10.1093/ijnp/pyab004 |
0.577 |
|
2021 |
Agabio R, Baldwin DS, Amaro H, Leggio L, Sinclair JMA. The influence of anxiety symptoms on clinical outcomes during baclofen treatment of alcohol use disorder: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews. PMID 33454289 DOI: 10.1016/j.neubiorev.2020.12.030 |
0.367 |
|
2020 |
Marty VN, Farokhnia M, Munier JJ, Mulpuri Y, Leggio L, Spigelman I. Long-Acting Glucagon-Like Peptide-1 Receptor Agonists Suppress Voluntary Alcohol Intake in Male Wistar Rats. Frontiers in Neuroscience. 14: 599646. PMID 33424537 DOI: 10.3389/fnins.2020.599646 |
0.465 |
|
2020 |
Cobbina E, Lee MR, Leggio L, Akhlaghi F. A Population Pharmacokinetic Analysis of PF-5190457, a Novel Ghrelin Receptor Inverse Agonist in Healthy Volunteers and in Heavy Alcohol Drinkers. Clinical Pharmacokinetics. PMID 33155163 DOI: 10.1007/s40262-020-00942-7 |
0.543 |
|
2020 |
Haass-Koffler CL, Piacentino D, Li X, Long VM, Lee MR, Swift RM, Kenna GA, Leggio L. Differences in Sociodemographic and Alcohol-Related Clinical Characteristics Between Treatment Seekers and Nontreatment Seekers and Their Role in Predicting Outcomes in the COMBINE Study of Alcohol Use Disorder. Alcoholism, Clinical and Experimental Research. PMID 32997422 DOI: 10.1111/acer.14428 |
0.481 |
|
2020 |
Portelli J, Farokhnia M, Deschaine SL, Battista JT, Lee MR, Li X, Ron D, Leggio L. Investigating the link between serum concentrations of brain-derived neurotrophic factor and behavioral measures in anxious alcohol-dependent individuals. Alcohol (Fayetteville, N.Y.). PMID 32798692 DOI: 10.1016/j.alcohol.2020.07.009 |
0.461 |
|
2020 |
Spagnolo PA, Montemitro C, Leggio L. New Challenges in Addiction Medicine: COVID-19 Infection in Patients With Alcohol and Substance Use Disorders-The Perfect Storm. The American Journal of Psychiatry. appiajp202020040417. PMID 32660296 DOI: 10.1176/Appi.Ajp.2020.20040417 |
0.415 |
|
2020 |
Gray JC, Murphy M, Leggio L. Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity. Drug and Alcohol Dependence. 214: 108155. PMID 32652377 DOI: 10.1016/j.drugalcdep.2020.108155 |
0.419 |
|
2020 |
Haass-Koffler CL, Perciballi R, Brown ZE, Lee MR, Zywiak WH, Kurtis J, Swift RM, Leggio L. Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders. The American Journal On Addictions. PMID 32488890 DOI: 10.1111/Ajad.13064 |
0.415 |
|
2020 |
Farokhnia M, Portelli J, Lee MR, McDiarmid GR, Munjal V, Abshire KM, Battista JT, Browning BD, Deschaine SL, Akhlaghi F, Leggio L. Effects of exogenous ghrelin administration and ghrelin receptor blockade, in combination with alcohol, on peripheral inflammatory markers in heavy-drinking individuals: Results from two human laboratory studies. Brain Research. 146851. PMID 32339499 DOI: 10.1016/J.Brainres.2020.146851 |
0.421 |
|
2020 |
Ehinger Y, Phamluong K, Darevesky D, Welman M, Moffat JJ, Sakhai SA, Whiteley EL, Berger AL, Laguesse S, Farokhnia M, Leggio L, Lordkipanidzé M, Ron D. Differential correlation of serum BDNF and microRNA content in rats with rapid or late onset of heavy alcohol use. Addiction Biology. e12890. PMID 32135570 DOI: 10.1111/adb.12890 |
0.494 |
|
2020 |
Daurio AM, Deschaine SL, Modabbernia A, Leggio L. Parsing out the role of dopamine D4 receptor gene (DRD4) on alcohol-related phenotypes: A meta-analysis and systematic review. Addiction Biology. 25: e12770. PMID 31149768 DOI: 10.1111/adb.12770 |
0.455 |
|
2019 |
Litten RZ, Falk DE, Ryan ML, Fertig J, Leggio L. Five Priority Areas for Improving Medications Development for Alcohol Use Disorder and Promoting Their Routine Use in Clinical Practice. Alcoholism, Clinical and Experimental Research. PMID 31803968 DOI: 10.1111/acer.14233 |
0.367 |
|
2019 |
Witkiewitz K, Litten RZ, Leggio L. Advances in the science and treatment of alcohol use disorder. Science Advances. 5: eaax4043. PMID 31579824 DOI: 10.1126/Sciadv.Aax4043 |
0.5 |
|
2019 |
Lee MR, Farokhnia M, Cobbina E, Saravanakumar A, Li X, Battista JT, Farinelli LA, Akhlaghi F, Leggio L. Endocrine effects of the novel ghrelin receptor inverse agonist PF-5190457: Results from a placebo-controlled human laboratory alcohol co-administration study in heavy drinkers. Neuropharmacology. 107788. PMID 31557492 DOI: 10.1016/J.Neuropharm.2019.107788 |
0.487 |
|
2019 |
Portelli J, Wiers CE, Li X, Deschaine SL, McDiarmid GR, Bermpohl F, Leggio L. Peripheral proinflammatory markers are upregulated in abstinent alcohol-dependent patients but are not affected by cognitive bias modification: Preliminary findings. Drug and Alcohol Dependence. 204: 107553. PMID 31541874 DOI: 10.1016/j.drugalcdep.2019.107553 |
0.331 |
|
2019 |
Lee MR, Sankar V, Hammer A, Kennedy WG, Barb JJ, McQueen PG, Leggio L. Using Machine Learning to Classify Individuals With Alcohol Use Disorder Based on Treatment Seeking Status. Eclinicalmedicine. 12: 70-78. PMID 31388665 DOI: 10.1016/J.Eclinm.2019.05.008 |
0.398 |
|
2019 |
Lee MR, Shin JH, Deschaine S, Daurio AM, Stangl BL, Yan J, Ramchandani VA, Schwandt ML, Grodin EN, Momenan R, Corral-Frias NS, Hariri AR, Bogdan R, Alvarez VA, Leggio L. A role for the rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, and functional MRI in humans. The American Journal of Drug and Alcohol Abuse. 1-13. PMID 31365285 DOI: 10.1080/00952990.2019.1638928 |
0.376 |
|
2019 |
Haass-Koffler CL, Long VM, Farokhnia M, Magill M, Kenna GA, Swift RM, Leggio L. Intravenous administration of ghrelin increases serum cortisol and aldosterone concentrations in heavy-drinking alcohol-dependent individuals: Results from a double-blind, placebo-controlled human laboratory study. Neuropharmacology. 107711. PMID 31310775 DOI: 10.1016/j.neuropharm.2019.107711 |
0.512 |
|
2019 |
Agabio R, Leggio L. HIV and alcohol use disorder: we cannot ignore the elephant in the room. The Lancet. Hiv. 6: e485-e486. PMID 31109914 DOI: 10.1016/S2352-3018(19)30074-8 |
0.385 |
|
2019 |
Farokhnia M, Browning BD, Leggio L. Prospects for pharmacotherapies to treat alcohol use disorder: an update on recent human studies. Current Opinion in Psychiatry. PMID 31107292 DOI: 10.1097/YCO.0000000000000519 |
0.491 |
|
2019 |
Tunstall BJ, Kirson D, Zallar LJ, McConnell SA, Vendruscolo JCM, Ho CP, Oleata CS, Khom S, Manning M, Lee MR, Leggio L, Koob GF, Roberto M, Vendruscolo LF. Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala. Plos Biology. 17: e2006421. PMID 30990816 DOI: 10.1371/Journal.Pbio.2006421 |
0.586 |
|
2019 |
Farokhnia M, Faulkner ML, Piacentino D, Lee MR, Leggio L. Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder. Physiology & Behavior. PMID 30738971 DOI: 10.1016/j.physbeh.2019.02.008 |
0.713 |
|
2019 |
Byrd N, Stangl B, Schwandt M, Farokhnia M, Leggio L, Ramchandani V. 3465 EXAMINING THE EFFECTS OF CHILDHOOD TRAUMA ON ADULT ALCOHOL CONSUMPTION: DOES RACE AND/OR SEX MATTER? Journal of Clinical and Translational Science. 3: 44-44. DOI: 10.1017/cts.2019.104 |
0.435 |
|
2019 |
Agabio R, Sinclair J, Leggio L. The Cagliari Statement on baclofen for the treatment of alcohol use disorder: An International Consensus French Journal of Psychiatry. 1: S28. DOI: 10.1016/j.fjpsy.2019.10.216 |
0.476 |
|
2018 |
Zallar LJ, Beurmann S, Tunstall BJ, Fraser CM, Koob GF, Vendruscolo LF, Leggio L. Ghrelin receptor deletion reduces binge-like alcohol drinking in rats. Journal of Neuroendocrinology. e12663. PMID 30456835 DOI: 10.1111/Jne.12663 |
0.582 |
|
2018 |
Agabio R, Sinclair JM, Addolorato G, Aubin HJ, Beraha EM, Caputo F, Chick JD, de La Selle P, Franchitto N, Garbutt JC, Haber PS, Heydtman M, Jaury P, Lingford-Hughes AR, Morley KC, ... ... Leggio L, et al. Baclofen for the treatment of alcohol use disorder: the Cagliari Statement. The Lancet. Psychiatry. PMID 30413394 DOI: 10.1016/S2215-0366(18)30303-1 |
0.479 |
|
2018 |
Agabio R, Sinclair JM, Leggio L. Baclofen and alcohol in France - Authors' reply. The Lancet. Psychiatry. 5: 962-963. PMID 30413393 DOI: 10.1016/S2215-0366(18)30433-4 |
0.538 |
|
2018 |
Falk DE, Ryan ML, Fertig JB, Devine EG, Cruz R, Brown ES, Burns H, Salloum IM, Newport DJ, Mendelson J, Galloway G, Kampman K, Brooks C, Green AI, Brunette MF, ... ... Leggio L, et al. Gabapentin Enacarbil Extended-Release for Alcohol Use Disorder: A Randomized, Double-Blind, Placebo-Controlled, Multisite Trial assessing Efficacy and Safety. Alcoholism, Clinical and Experimental Research. PMID 30403402 DOI: 10.1111/Acer.13917 |
0.425 |
|
2018 |
Farokhnia M, Deschaine SL, Sadighi A, Farinelli LA, Lee MR, Akhlaghi F, Leggio L. A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation. Molecular Psychiatry. PMID 30382188 DOI: 10.1038/S41380-018-0287-Y |
0.556 |
|
2018 |
Leggio L, de Witte P, Chick J. Alcohol and Alcoholism: Then, Now and The Future of 'The Red Journal'. Alcohol and Alcoholism (Oxford, Oxfordshire). 53: 637-638. PMID 30339185 DOI: 10.1093/alcalc/agy075 |
0.555 |
|
2018 |
Agabio R, Leggio L. Baclofen in the Treatment of Patients With Alcohol Use Disorder and Other Mental Health Disorders. Frontiers in Psychiatry. 9: 464. PMID 30323774 DOI: 10.3389/fpsyt.2018.00464 |
0.318 |
|
2018 |
Farokhnia M, Lee MR, Farinelli LA, Ramchandani VA, Akhlaghi F, Leggio L. Pharmacological manipulation of the ghrelin system and alcohol hangover symptoms in heavy drinking individuals: Is there a link? Pharmacology, Biochemistry, and Behavior. PMID 30030128 DOI: 10.1016/J.Pbb.2018.07.004 |
0.556 |
|
2018 |
Morley KC, Baillie A, van den Brink W, Chitty K, Brady K, Back S, Sutherland G, Seth D, Leggio L, Haber PS. Rationale for N-acetyl cysteine in the treatment of alcohol use disorder in patients with liver disease. Expert Opinion On Investigational Drugs. PMID 30019966 DOI: 10.1080/13543784.2018.1501471 |
0.502 |
|
2018 |
Bouhlal S, Farokhnia M, Lee MR, Akhlaghi F, Leggio L. Identifying and Characterizing Subpopulations of Heavy Alcohol Drinkers Via a Sucrose Preference Test: A Sweet Road to a Better Phenotypic Characterization? Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 30016385 DOI: 10.1093/Alcalc/Agy048 |
0.458 |
|
2018 |
Morris LS, Voon V, Leggio L. Stress, motivation and the gut-brain axis: A focus on the ghrelin system and alcohol use disorder. Alcoholism, Clinical and Experimental Research. PMID 29797564 DOI: 10.1111/acer.13781 |
0.4 |
|
2018 |
Lee MR, Tapocik JD, Ghareeb M, Schwandt ML, Dias AA, Le AN, Cobbina E, Farinelli LA, Bouhlal S, Farokhnia M, Heilig M, Akhlaghi F, Leggio L. The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study. Molecular Psychiatry. PMID 29728704 DOI: 10.1038/S41380-018-0064-Y |
0.539 |
|
2018 |
Haass-Koffler CL, Goodyear K, Zywiak WH, Leggio L, Kenna GA, Swift RM. Corrigendum: Comparing and Combining Topiramate and Aripiprazole on Alcohol-Related Outcomes in a Human Laboratory Study. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 29718153 DOI: 10.1093/alcalc/agy030 |
0.454 |
|
2018 |
Farokhnia M, Sheskier MB, Lee MR, Le AN, Singley E, Bouhlal S, Ton T, Zhao Z, Leggio L. Neuroendocrine response to GABA-B receptor agonism in alcohol-dependent individuals: Results from a combined outpatient and human laboratory experiment. Neuropharmacology. PMID 29665351 DOI: 10.1016/j.neuropharm.2018.04.011 |
0.465 |
|
2018 |
Haass-Koffler CL, Swift RM, Leggio L. Noradrenergic targets for the treatment of alcohol use disorder. Psychopharmacology. PMID 29460163 DOI: 10.1007/s00213-018-4843-6 |
0.416 |
|
2018 |
Haass-Koffler CL, Goodyear K, Loche A, Long VM, Lobina C, Tran HH, Cacciaglia R, Swift RM, Colombo G, Leggio L. Administration of the metabotropic glutamate receptor subtype 5 allosteric modulator GET7 3 with alcohol: A translational study in rats and humans. Journal of Psychopharmacology (Oxford, England). 269881117746904. PMID 29361897 DOI: 10.1177/0269881117746904 |
0.528 |
|
2017 |
Haass-Koffler CL, Goodyear K, Zywiak WH, Leggio L, Kenna GA, Swift RM. Comparing and Combining Topiramate and Aripiprazole on Alcohol-Related Outcomes in a Human Laboratory Study. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 29281033 DOI: 10.1093/alcalc/agx108 |
0.393 |
|
2017 |
Farokhnia M, Grodin EN, Lee MR, Oot EN, Blackburn AN, Stangl BL, Schwandt ML, Farinelli LA, Momenan R, Ramchandani VA, Leggio L. Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals. Molecular Psychiatry. PMID 29133954 DOI: 10.1038/Mp.2017.226 |
0.574 |
|
2017 |
Daurio AM, Aston SA, Schwandt ML, Bukhari MO, Bouhlal S, Farokhnia M, Lee MR, Leggio L. Impulsive personality traits mediate the relationship between adult attention deficit hyperactivity symptoms and alcohol dependence severity. Alcoholism, Clinical and Experimental Research. PMID 29063627 DOI: 10.1111/Acer.13538 |
0.303 |
|
2017 |
Lee MR, Schwandt ML, Sankar V, Suchankova P, Sun H, Leggio L. Effect of alcohol use disorder on oxytocin peptide and receptor mRNA expression in human brain: A post-mortem case-control study. Psychoneuroendocrinology. 85: 14-19. PMID 28787642 DOI: 10.1016/J.Psyneuen.2017.07.481 |
0.508 |
|
2017 |
Haass-Koffler CL, Goodyear K, Zywiak WH, Magill M, Eltinge SE, Wallace PM, Long VM, Jayaram-Lindström N, Swift RM, Kenna GA, Leggio L. Higher pretreatment blood pressure is associated with greater alcohol drinking reduction in alcohol-dependent individuals treated with doxazosin. Drug and Alcohol Dependence. 177: 23-28. PMID 28551590 DOI: 10.1016/j.drugalcdep.2017.03.016 |
0.493 |
|
2017 |
Temko JE, Bouhlal S, Farokhnia M, Lee MR, Cryan JF, Leggio L. The Microbiota, the Gut and the Brain in Eating and Alcohol Use Disorders: A 'Ménage à Trois'? Alcohol and Alcoholism (Oxford, Oxfordshire). 1-11. PMID 28482009 DOI: 10.1093/alcalc/agx024 |
0.369 |
|
2017 |
Suchankova P, Yan J, Schwandt ML, Stangl BL, Jerlhag E, Engel JA, Hodgkinson CA, Ramchandani VA, Leggio L. The Leu72Met Polymorphism of the Prepro-ghrelin Gene is Associated With Alcohol Consumption and Subjective Responses to Alcohol: Preliminary Findings. Alcohol and Alcoholism (Oxford, Oxfordshire). 1-6. PMID 28481975 DOI: 10.1093/Alcalc/Agx021 |
0.556 |
|
2017 |
Aoun EG, Jimenez VA, Vendruscolo LF, Walter NAR, Barbier E, Ferrulli A, Haass-Koffler CL, Darakjian P, Lee MR, Addolorato G, Heilig M, Hitzemann R, Koob GF, Grant KA, Leggio L. A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans. Molecular Psychiatry. PMID 28461696 DOI: 10.1038/Mp.2017.97 |
0.434 |
|
2017 |
Farokhnia M, Schwandt ML, Lee MR, Bollinger JW, Farinelli LA, Amodio JP, Sewell L, Lionetti TA, Spero DE, Leggio L. Biobehavioral effects of baclofen in anxious alcohol-dependent individuals: a randomized, double-blind, placebo-controlled, laboratory study. Translational Psychiatry. 7: e1108. PMID 28440812 DOI: 10.1038/Tp.2017.71 |
0.566 |
|
2017 |
Rohn MC, Lee MR, Kleuter SB, Schwandt ML, Falk DE, Leggio L. Differences Between Treatment-Seeking and Nontreatment-Seeking Alcohol-Dependent Research Participants: An Exploratory Analysis. Alcoholism, Clinical and Experimental Research. 41: 414-420. PMID 28129451 DOI: 10.1111/Acer.13304 |
0.461 |
|
2017 |
Haass-Koffler CL, Akhlaghi F, Swift RM, Leggio L. Altering ethanol pharmacokinetics to treat alcohol use disorder: Can you teach an old dog new tricks? Journal of Psychopharmacology (Oxford, England). 269881116684338. PMID 28093021 DOI: 10.1177/0269881116684338 |
0.453 |
|
2017 |
Haass-Koffler CL, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK, Lasek AW, Magill M, Schwandt ML, Momenan R, Hodgkinson CA, Bartlett SE, Swift RM, Bonci A, Leggio L. A chimeric approach to evaluate the role of corticotropin releasing factor in alcohol use disorder Alcohol. 60: 222-223. DOI: 10.1016/J.Alcohol.2017.02.267 |
0.411 |
|
2017 |
Leggio L. Ghrelin as potential new pathway toward medication development for alcohol use disorder: Recent clinical data Alcohol. 60: 218. DOI: 10.1016/J.ALCOHOL.2017.02.248 |
0.399 |
|
2016 |
Leggio L, Lee MR. Treatment of Alcohol Use Disorder in Patients with Alcoholic Liver Disease. The American Journal of Medicine. PMID 27984008 DOI: 10.1016/j.amjmed.2016.10.004 |
0.51 |
|
2016 |
Goodyear K, Lee MR, Schwandt ML, Hodgkinson CA, Leggio L. Hepatic, lipid and genetic factors associated with obesity: crosstalk with alcohol dependence? The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-9. PMID 27905213 DOI: 10.1080/15622975.2016.1249952 |
0.451 |
|
2016 |
Haass-Koffler CL, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK, Lasek AW, Magill M, Schwandt ML, Momenan R, Hodgkinson CA, Bartlett SE, Swift RM, Bonci A, Leggio L. Defining the role of corticotropin releasing factor binding protein in alcohol consumption. Translational Psychiatry. 6: e953. PMID 27845775 DOI: 10.1038/Tp.2016.208 |
0.419 |
|
2016 |
Martinotti G, Lupi M, Carlucci L, Santacroce R, Cinosi E, Acciavatti T, Sarchione F, Verrastro V, Diotaiuti P, Petruccelli I, Ferrari S, Nanni MG, Pinna F, Volpe U, Saggino A, ... ... Leggio L, et al. Alcohol drinking patterns in young people: A survey-based study. Journal of Health Psychology. PMID 27624615 DOI: 10.1177/1359105316667795 |
0.448 |
|
2016 |
Blackburn AN, Hajnal A, Leggio L. The gut in the brain: the effects of bariatric surgery on alcohol consumption. Addiction Biology. PMID 27578259 DOI: 10.1111/adb.12436 |
0.465 |
|
2016 |
Haass-Koffler CL, Giovenco DE, Lee MR, Zywiak WH, de la Monte SM, Kenna GA, Swift RM, Leggio L. Serum Insulin Levels are Reduced by Intravenous Ghrelin Administration but do not Correlate with Alcohol Craving in Alcohol Dependent Individuals. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 27207912 DOI: 10.1093/ijnp/pyw048 |
0.471 |
|
2016 |
Schwandt ML, Cortes CR, Kwako LE, George DT, Momenan R, Sinha R, Grigoriadis DE, Leggio L, Heilig M. The CRF1 Antagonist Verucerfont in Anxious Alcohol Dependent Women: Translation of Neuroendocrine, but not of Anti-Craving Effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27109623 DOI: 10.1038/Npp.2016.61 |
0.526 |
|
2016 |
Lee MR, Rohn MC, Tanda G, Leggio L. Targeting the Oxytocin System to Treat Addictive Disorders: Rationale and Progress to Date. Cns Drugs. PMID 26932552 DOI: 10.1007/s40263-016-0313-z |
0.36 |
|
2016 |
Heilig M, Leggio L. What the alcohol doctor ordered from the neuroscientist: Theragnostic biomarkers for personalized treatments. Progress in Brain Research. 224: 401-18. PMID 26822368 DOI: 10.1016/Bs.Pbr.2015.07.023 |
0.475 |
|
2016 |
Leggio L. Role of the ghrelin system in alcoholism: Acting on the growth hormone secretagogue receptor to treat alcohol-related diseases. Drug News & Perspectives. 23: 157-66. PMID 20440417 DOI: 10.1358/dnp.2010.23.3.1429490 |
0.566 |
|
2016 |
Joseph PV, Fourie NH, Ferguson E, Abey SK, Walter P, Sherwin LB, Rahim-Williams B, Leggio L, Henderson WA. Sa1982 Liquid Chromatography Mass Spectrometry Based Analysis of Human Response to Synthetic Sugar Challenge and the Microbiome Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)31470-6 |
0.638 |
|
2015 |
Lee MR, Leggio L. Management of Alcohol Use Disorder in Patients Requiring Liver Transplant. The American Journal of Psychiatry. 172: 1182-9. PMID 26619772 DOI: 10.1176/appi.ajp.2015.15040567 |
0.34 |
|
2015 |
Haass-Koffler CL, Aoun EG, Swift RM, de la Monte SM, Kenna GA, Leggio L. Leptin levels are reduced by intravenous ghrelin administration and correlated with cue-induced alcohol craving. Translational Psychiatry. 5: e646. PMID 26418274 DOI: 10.1038/tp.2015.140 |
0.506 |
|
2015 |
Lee MR, Schwandt ML, Bollinger JW, Dias AA, Oot EN, Goldman D, Hodgkinson CA, Leggio L. Effect of Functionally Significant Deiodinase Single Nucleotide Polymorphisms on Drinking Behavior in Alcohol Dependence: An Exploratory Investigation. Alcoholism, Clinical and Experimental Research. PMID 26207529 DOI: 10.1111/Acer.12814 |
0.456 |
|
2015 |
Suchankova P, Yan J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Jerlhag E, Engel JA, Hodgkinson CA, Egli M, Lopez MF, Becker HC, Goldman D, Heilig M, Ramchandani VA, ... Leggio L, et al. The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence. Translational Psychiatry. 5: e583. PMID 26080318 DOI: 10.1038/Tp.2015.68 |
0.556 |
|
2015 |
Kenna GA, Haass-Koffler CL, Zywiak WH, Edwards SM, Brickley MB, Swift RM, Leggio L. Role of the α1 blocker doxazosin in alcoholism: a proof-of-concept randomized controlled trial. Addiction Biology. PMID 26037245 DOI: 10.1111/adb.12275 |
0.424 |
|
2015 |
Farokhnia M, Edwards SM, Bollinger J, Amodio J, Zywiak WH, Tidey JW, Swift RM, Kenna GA, Leggio L. T76. Baclofen as a pharmacotherapy for the treatment of concurrent alcohol and nicotine dependence: a double-blind, placebo-controlled, randomized trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1560. PMID 25868070 DOI: 10.1038/Npp.2015.29 |
0.322 |
|
2015 |
Haass-Koffler CL, Leggio L, Davidson D, Swift RM. Effects of idazoxan on alcohol pharmacokinetics and intoxication: a preliminary human laboratory study. Alcoholism, Clinical and Experimental Research. 39: 594-602. PMID 25833022 DOI: 10.1111/Acer.12658 |
0.547 |
|
2015 |
Leggio L, Zywiak WH, Edwards SM, Tidey JW, Swift RM, Kenna GA. Erratum to: a preliminary double-blind, placebo-controlled randomized study of baclofen effects in alcoholic smokers. Psychopharmacology. 232: 1667. PMID 25804430 DOI: 10.1007/s00213-015-3916-z |
0.441 |
|
2015 |
Mirijello A, D'Angelo C, Ferrulli A, Vassallo G, Antonelli M, Caputo F, Leggio L, Gasbarrini A, Addolorato G. Identification and management of alcohol withdrawal syndrome. Drugs. 75: 353-65. PMID 25666543 DOI: 10.1007/s40265-015-0358-1 |
0.375 |
|
2015 |
Aoun EG, Lee MR, Haass-Koffler CL, Swift RM, Addolorato G, Kenna GA, Leggio L. Relationship between the thyroid axis and alcohol craving. Alcohol and Alcoholism (Oxford, Oxfordshire). 50: 24-9. PMID 25433251 DOI: 10.1093/alcalc/agu085 |
0.4 |
|
2015 |
Hillemacher T, Leggio L, Heberlein A. Investigational therapies for the pharmacological treatment of alcoholism. Expert Opinion On Investigational Drugs. 24: 17-30. PMID 25164385 DOI: 10.1517/13543784.2014.954037 |
0.469 |
|
2015 |
Leggio L, Zywiak WH, Edwards SM, Tidey JW, Swift RM, Kenna GA. A preliminary double-blind, placebo-controlled randomized study of baclofen effects in alcoholic smokers. Psychopharmacology. 232: 233-43. PMID 24973894 DOI: 10.1007/S00213-014-3652-9 |
0.488 |
|
2015 |
Kenna G, Haass-Koffler C, Swift R, Zywiak W, Brickley M, Edwards S, Leggio L. P86A PILOT DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL USING DOXAZOSIN FOR ALCOHOL DEPENDENCE Alcohol and Alcoholism. 50: i67.2-i67. DOI: 10.1093/alcalc/agv080.86 |
0.422 |
|
2015 |
Suchankova P, Yan, J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Hodgkinson CA, Goldman D, Heilig M, Ramchandani VA, Nilsson S, von der Pahlen B, Santtila P, Sandnabba K, ... ... Leggio L, et al. SY15-3THE ROLE OF THE GUT-BRAIN-AXIS IN SUBSTANCE USE DISORDERS: EVIDENCE FROM HUMAN GENETIC STUDIES Alcohol and Alcoholism. 50: i18.1-i18. DOI: 10.1093/Alcalc/Agv076.63 |
0.345 |
|
2015 |
Leggio L. SY09-5UPDATE ON EFFECTIVE TREATMENTS FOR ALCOHOL USE DISORDER: RIDING THE WAVES OF MEDICATIONS DEVELOPMENT Alcohol and Alcoholism. 50: i11.3-i11. DOI: 10.1093/ALCALC/AGV076.38 |
0.372 |
|
2014 |
Morley KC, Baillie A, Leung S, Addolorato G, Leggio L, Haber PS. Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 25246489 DOI: 10.1093/Alcalc/Agu062 |
0.447 |
|
2014 |
Kenna GA, Zywiak WH, Swift RM, McGeary JE, Clifford JS, Shoaff JR, Fricchione S, Brickley M, Beaucage K, Haass-Koffler CL, Leggio L. Ondansetron and sertraline may interact with 5-HTTLPR and DRD4 polymorphisms to reduce drinking in non-treatment seeking alcohol-dependent women: exploratory findings. Alcohol (Fayetteville, N.Y.). 48: 515-22. PMID 25212749 DOI: 10.1016/J.Alcohol.2014.04.005 |
0.363 |
|
2014 |
Vuittonet CL, Halse M, Leggio L, Fricchione SB, Brickley M, Haass-Koffler CL, Tavares T, Swift RM, Kenna GA. Pharmacotherapy for alcoholic patients with alcoholic liver disease. American Journal of Health-System Pharmacy : Ajhp : Official Journal of the American Society of Health-System Pharmacists. 71: 1265-76. PMID 25027533 DOI: 10.2146/ajhp140028 |
0.447 |
|
2014 |
Leggio L, Schwandt ML. Topiramate for alcoholism treatment: novel pharmacogenetic evidence for the journey to personalized medicine? The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1541-4. PMID 24892413 DOI: 10.1017/S1461145714000790 |
0.342 |
|
2014 |
Leggio L, Zywiak WH, Fricchione SR, Edwards SM, de la Monte SM, Swift RM, Kenna GA. Intravenous ghrelin administration increases alcohol craving in alcohol-dependent heavy drinkers: a preliminary investigation. Biological Psychiatry. 76: 734-41. PMID 24775991 DOI: 10.1016/j.biopsych.2014.03.019 |
0.581 |
|
2014 |
Kenna GA, Zywiak WH, Swift RM, McGeary JE, Clifford JS, Shoaff JR, Vuittonet C, Fricchione S, Brickley M, Beaucage K, Haass-Koffler CL, Leggio L. Ondansetron reduces naturalistic drinking in nontreatment-seeking alcohol-dependent individuals with the LL 5'-HTTLPR genotype: a laboratory study. Alcoholism, Clinical and Experimental Research. 38: 1567-74. PMID 24773166 DOI: 10.1111/Acer.12410 |
0.448 |
|
2014 |
Haass-Koffler CL, Leggio L, Kenna GA. Pharmacological approaches to reducing craving in patients with alcohol use disorders. Cns Drugs. 28: 343-60. PMID 24573997 DOI: 10.1007/s40263-014-0149-3 |
0.504 |
|
2014 |
Lee MR, Leggio L. Combined pharmacotherapies for the management of alcoholism: rationale and evidence to date. Cns Drugs. 28: 107-19. PMID 24497006 DOI: 10.1007/s40263-013-0137-z |
0.393 |
|
2013 |
Polston JE, Pritchett CE, Tomasko JM, Rogers AM, Leggio L, Thanos PK, Volkow ND, Hajnal A. Roux-en-Y gastric bypass increases intravenous ethanol self-administration in dietary obese rats. Plos One. 8: e83741. PMID 24391816 DOI: 10.1371/Journal.Pone.0083741 |
0.502 |
|
2013 |
Leggio L, Schwandt ML, Oot EN, Dias AA, Ramchandani VA. Fasting-induced increase in plasma ghrelin is blunted by intravenous alcohol administration: a within-subject placebo-controlled study. Psychoneuroendocrinology. 38: 3085-91. PMID 24090583 DOI: 10.1016/J.Psyneuen.2013.09.005 |
0.557 |
|
2013 |
Addolorato G, Mirijello A, Leggio L. Alcohol addiction: toward a patient-oriented pharmacological treatment. Expert Opinion On Pharmacotherapy. 14: 2157-60. PMID 23984836 DOI: 10.1517/14656566.2013.834047 |
0.468 |
|
2013 |
Gurvich EM, Kenna GA, Leggio L. Use of novel technology-based techniques to improve alcohol-related outcomes in clinical trials. Alcohol and Alcoholism (Oxford, Oxfordshire). 48: 712-9. PMID 23955872 DOI: 10.1093/alcalc/agt134 |
0.446 |
|
2013 |
Addolorato G, Mirijello A, Leggio L, Ferrulli A, D'Angelo C, Vassallo G, Cossari A, Gasbarrini G, Landolfi R, Agnes S, Gasbarrini A, Abbate V, Abenavoli L, Antonelli M, Annicchiarico E, et al. Liver transplantation in alcoholic patients: Impact of an alcohol addiction unit within a liver transplant center Alcoholism: Clinical and Experimental Research. 37: 1601-1608. PMID 23578009 DOI: 10.1111/acer.12117 |
0.432 |
|
2013 |
Addolorato G, Mirijello A, Leggio L, Ferrulli A, Landolfi R. Management of alcohol dependence in patients with liver disease. Cns Drugs. 27: 287-99. PMID 23456576 DOI: 10.1007/s40263-013-0043-4 |
0.513 |
|
2013 |
Leggio L, Kenna GA. Commentary: Doxazosin for alcoholism. Alcoholism, Clinical and Experimental Research. 37: 191-3. PMID 23278505 DOI: 10.1111/acer.12064 |
0.425 |
|
2013 |
Leggio L, Zywiak WH, McGeary JE, Edwards S, Fricchione SR, Shoaff JR, Addolorato G, Swift RM, Kenna GA. A human laboratory pilot study with baclofen in alcoholic individuals. Pharmacology, Biochemistry, and Behavior. 103: 784-91. PMID 23262301 DOI: 10.1016/J.Pbb.2012.11.013 |
0.567 |
|
2013 |
Johnson B, Seneviratne C, Franklin J, Beckett K, Ma J, Ait-Daoud N, Payne T, Johnson B, Li M, Ait-Daoud N, Kenna G, Zywiak WH, McGeary JE, Swift RM, Clifford JS, ... ... Leggio L, et al. S02 * SEROTONIN SYSTEM IN ALCOHOLISM: INDIVIDUAL DIFFERENCES AND TREATMENT Alcohol and Alcoholism. 48: i3-i4. DOI: 10.1093/Alcalc/Agt074 |
0.462 |
|
2012 |
Heberlein A, Leggio L, Stichtenoth D, Hillemacher T. The treatment of alcohol and opioid dependence in pregnant women. Current Opinion in Psychiatry. 25: 559-64. PMID 23037965 DOI: 10.1097/YCO.0b013e328358ad36 |
0.334 |
|
2012 |
Kenna GA, Swift RM, Hillemacher T, Leggio L. The relationship of appetitive, reproductive and posterior pituitary hormones to alcoholism and craving in humans. Neuropsychology Review. 22: 211-28. PMID 22772772 DOI: 10.1007/s11065-012-9209-y |
0.562 |
|
2012 |
Tang YL, Hao W, Leggio L. Treatments for alcohol-related disorders in China: a developing story. Alcohol and Alcoholism (Oxford, Oxfordshire). 47: 563-70. PMID 22683652 DOI: 10.1093/alcalc/ags066 |
0.328 |
|
2012 |
Caputo F, Vignoli T, Leggio L, Addolorato G, Zoli G, Bernardi M. Alcohol use disorders in the elderly: a brief overview from epidemiology to treatment options. Experimental Gerontology. 47: 411-6. PMID 22575256 DOI: 10.1016/j.exger.2012.03.019 |
0.528 |
|
2012 |
Leggio L, Promrat K, Kenna GA. A Call to Action: Alcohol Interventions in HIV-Infected Patients. Frontiers in Psychiatry. 3: 35. PMID 22529825 DOI: 10.3389/fpsyt.2012.00035 |
0.317 |
|
2012 |
Leggio L, Ferrulli A, Zambon A, Caputo F, Kenna GA, Swift RM, Addolorato G. Baclofen promotes alcohol abstinence in alcohol dependent cirrhotic patients with hepatitis C virus (HCV) infection. Addictive Behaviors. 37: 561-4. PMID 22244707 DOI: 10.1016/j.addbeh.2011.12.010 |
0.396 |
|
2012 |
Addolorato G, Leggio L, Hopf FW, Diana M, Bonci A. Novel therapeutic strategies for alcohol and drug addiction: focus on GABA, ion channels and transcranial magnetic stimulation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 163-77. PMID 22030714 DOI: 10.1038/npp.2011.216 |
0.358 |
|
2012 |
Leggio L, Ferrulli A, Cardone S, Nesci A, Miceli A, Malandrino N, Capristo E, Canestrelli B, Monteleone P, Kenna GA, Swift RM, Addolorato G. Ghrelin system in alcohol-dependent subjects: role of plasma ghrelin levels in alcohol drinking and craving. Addiction Biology. 17: 452-64. PMID 21392177 DOI: 10.1111/j.1369-1600.2010.00308.x |
0.552 |
|
2011 |
Leggio L, Kenna GA, Ferrulli A, Zywiak WH, Caputo F, Swift RM, Addolorato G. Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease. Human Psychopharmacology. 26: 554-9. PMID 22095793 DOI: 10.1002/hup.1244 |
0.537 |
|
2011 |
Addolorato G, Leggio L, Ferrulli A, Cardone S, Bedogni G, Caputo F, Gasbarrini G, Landolfi R. Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial. Alcohol and Alcoholism (Oxford, Oxfordshire). 46: 312-7. PMID 21414953 DOI: 10.1093/alcalc/agr017 |
0.415 |
|
2011 |
Caputo F, Francini S, Brambilla R, Vigna-Taglianti F, Stoppo M, Del Re A, Leggio L, Addolorato G, Zoli G, Bernardi M. Sodium oxybate in maintaining alcohol abstinence in alcoholic patients with and without psychiatric comorbidity. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 21: 450-6. PMID 21276717 DOI: 10.1016/j.euroneuro.2010.12.005 |
0.539 |
|
2011 |
Leggio L, Addolorato G, Cippitelli A, Jerlhag E, Kampov-Polevoy AB, Swift RM. Role of feeding-related pathways in alcohol dependence: A focus on sweet preference, NPY, and ghrelin. Alcoholism, Clinical and Experimental Research. 35: 194-202. PMID 21058960 DOI: 10.1111/j.1530-0277.2010.01334.x |
0.536 |
|
2011 |
Montalto M, Gallo A, Ferrulli A, Visca D, Campobasso E, Cardone S, D'Onofrio F, Santoro L, Covino M, Mirijello A, Leggio L, Gasbarrini G, Addolorato G. Fecal calprotectin concentrations in alcoholic patients: a longitudinal study. European Journal of Gastroenterology & Hepatology. 23: 76-80. PMID 21030869 DOI: 10.1097/MEG.0b013e32834101f9 |
0.528 |
|
2011 |
Leggio L. Alcohol and Tobacco. Medical and Sociological Aspects of Use, Abuse and Addiction Alcohol and Alcoholism. 46: 366-366. DOI: 10.1093/ALCALC/AGR022 |
0.431 |
|
2011 |
Leggio L. S.08.04 Relationship between ghrelin and alcohol craving and intake: recent clinical findings European Neuropsychopharmacology. 21: S199. DOI: 10.1016/S0924-977X(11)70272-3 |
0.495 |
|
2010 |
Ray LA, Krull JL, Leggio L. The Effects of Naltrexone Among Alcohol Non-Abstainers: Results from the COMBINE Study. Frontiers in Psychiatry. 1: 26. PMID 21423437 DOI: 10.3389/Fpsyt.2010.00026 |
0.505 |
|
2010 |
Ferrulli A, Leggio L, Cardone S, D'Angelo C, Mirijello A, Vonghia L, Miceli A, Gasbarrini G, Addolorato G. Psychosocial findings in alcohol-dependent patients before and after three months of total alcohol abstinence. Frontiers in Psychiatry. 1: 17. PMID 21423428 DOI: 10.3389/fpsyt.2010.00017 |
0.476 |
|
2010 |
Addolorato G, Leggio L. Pregabalin similar to lorazepam for alcohol withdrawal symptoms. Evidence-Based Medicine. 15: 73. PMID 20522678 DOI: 10.1136/ebm1069 |
0.45 |
|
2010 |
Addolorato G, Leggio L. Safety and efficacy of baclofen in the treatment of alcohol-dependent patients. Current Pharmaceutical Design. 16: 2113-7. PMID 20482507 |
0.558 |
|
2010 |
Leggio L, Cardone S, Ferrulli A, Kenna GA, Diana M, Swift RM, Addolorato G. Turning the clock ahead: potential preclinical and clinical neuropharmacological targets for alcohol dependence. Current Pharmaceutical Design. 16: 2159-18. PMID 20482506 DOI: 10.2174/138161210791516369 |
0.454 |
|
2010 |
Leggio L, Addolorato G. Pharmacotherapy of alcohol dependence: past, present and future research. Current Pharmaceutical Design. 16: 2074-5. PMID 20482504 |
0.549 |
|
2010 |
Leggio L, Garbutt JC, Addolorato G. Effectiveness and safety of baclofen in the treatment of alcohol dependent patients. Cns & Neurological Disorders Drug Targets. 9: 33-44. PMID 20201813 DOI: 10.2174/187152710790966614 |
0.542 |
|
2009 |
Addolorato G, Leggio L, Cardone S, Ferrulli A, Gasbarrini G. Role of the GABA(B) receptor system in alcoholism and stress: focus on clinical studies and treatment perspectives. Alcohol (Fayetteville, N.Y.). 43: 559-63. PMID 19913201 DOI: 10.1016/j.alcohol.2009.09.031 |
0.541 |
|
2009 |
Kenna GA, Lomastro TL, Schiesl A, Leggio L, Swift RM. Review of topiramate: an antiepileptic for the treatment of alcohol dependence. Current Drug Abuse Reviews. 2: 135-42. PMID 19630744 DOI: 10.2174/1874473710902020135 |
0.495 |
|
2009 |
Kenna GA, Leggio L, Swift RM. A safety and tolerability laboratory study of the combination of aripiprazole and topiramate in volunteers who drink alcohol. Human Psychopharmacology. 24: 465-72. PMID 19551762 DOI: 10.1002/hup.1042 |
0.528 |
|
2009 |
Leggio L, Ray LA, Kenna GA, Swift RM. Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study. Alcoholism, Clinical and Experimental Research. 33: 1539-44. PMID 19485973 DOI: 10.1111/J.1530-0277.2009.00982.X |
0.405 |
|
2009 |
Leggio L. Understanding and treating alcohol craving and dependence: recent pharmacological and neuroendocrinological findings. Alcohol and Alcoholism (Oxford, Oxfordshire). 44: 341-52. PMID 19451661 DOI: 10.1093/alcalc/agp026 |
0.542 |
|
2009 |
Addolorato G, Russell M, Albano E, Haber PS, Wands JR, Leggio L. Understanding and treating patients with alcoholic cirrhosis: an update. Alcoholism, Clinical and Experimental Research. 33: 1136-44. PMID 19389182 DOI: 10.1111/J.1530-0277.2009.00956.X |
0.54 |
|
2009 |
Addolorato G, Leggio L, Ferrulli A, Caputo F, Gasbarrini A. The therapeutic potential of gamma-hydroxybutyric acid for alcohol dependence: balancing the risks and benefits. A focus on clinical data. Expert Opinion On Investigational Drugs. 18: 675-86. PMID 19379123 DOI: 10.1517/13543780902905855 |
0.521 |
|
2009 |
Addolorato G, Leggio L, Hillemacher T, Kraus T, Jerlhag E, Bleich S. Hormones and drinking behaviour: new findings on ghrelin, insulin, leptin and volume-regulating hormones. An ESBRA Symposium report. Drug and Alcohol Review. 28: 160-5. PMID 19320701 DOI: 10.1111/J.1465-3362.2008.00023.X |
0.461 |
|
2009 |
Leggio L, Kenna GA, Fenton M, Bonenfant E, Swift RM. Typologies of alcohol dependence. From Jellinek to genetics and beyond. Neuropsychology Review. 19: 115-29. PMID 19184441 DOI: 10.1007/S11065-008-9080-Z |
0.404 |
|
2009 |
Leggio L, Malandrino N, Ferrulli A, Cardone S, Miceli A, Gasbarrini G, Capristo E, Addolorato G. Is cortisol involved in the alcohol-related fat mass impairment? A longitudinal clinical study. Alcohol and Alcoholism (Oxford, Oxfordshire). 44: 211-5. PMID 19144979 DOI: 10.1093/alcalc/agn116 |
0.487 |
|
2009 |
Kenna GA, Zywiak WH, McGeary JE, Leggio L, McGeary C, Wang S, Grenga A, Swift RM. A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertraline. Alcoholism, Clinical and Experimental Research. 33: 315-23. PMID 19032576 DOI: 10.1111/J.1530-0277.2008.00835.X |
0.412 |
|
2009 |
Ray LA, Mackillop J, Leggio L, Morgan M, Hutchison KE. Effects of naltrexone on cortisol levels in heavy drinkers. Pharmacology, Biochemistry, and Behavior. 91: 489-94. PMID 18824022 DOI: 10.1016/J.Pbb.2008.09.004 |
0.504 |
|
2009 |
Swift R, Leggio L. Adjunctive pharmacotherapy in the treatment of alcohol and drug dependence Evidence-Based Addiction Treatment. 287-310. DOI: 10.1016/B978-0-12-374348-0.00015-X |
0.435 |
|
2008 |
Vonghia L, Leggio L, Ferrulli A, Bertini M, Gasbarrini G, Addolorato G. Acute alcohol intoxication. European Journal of Internal Medicine. 19: 561-7. PMID 19046719 DOI: 10.1016/j.ejim.2007.06.033 |
0.516 |
|
2008 |
Leggio L, Ferrulli A, Cardone S, Malandrino N, Mirijello A, D'Angelo C, Vonghia L, Miceli A, Capristo E, Kenna GA, Gasbarrini G, Swift RM, Addolorato G. Relationship between the hypothalamic-pituitary-thyroid axis and alcohol craving in alcohol-dependent patients: a longitudinal study. Alcoholism, Clinical and Experimental Research. 32: 2047-53. PMID 18828809 DOI: 10.1111/j.1530-0277.2008.00792.x |
0.409 |
|
2008 |
Caputo F, Francini S, Stoppo M, Lorenzini F, Vignoli T, Del Re A, Comaschi C, Leggio L, Addolorato G, Zoli G, Bernardi M. Incidence of craving for and abuse of gamma-hydroxybutyric acid (GHB) in different populations of treated alcoholics: an open comparative study. Journal of Psychopharmacology (Oxford, England). 23: 883-90. PMID 18635689 DOI: 10.1177/0269881108094620 |
0.426 |
|
2008 |
Leggio L, Ferrulli A, Cardone S, Miceli A, Kenna GA, Gasbarrini G, Swift RM, Addolorato G. Renin and aldosterone but not the natriuretic peptide correlate with obsessive craving in medium-term abstinent alcohol-dependent patients: a longitudinal study. Alcohol (Fayetteville, N.Y.). 42: 375-81. PMID 18486430 DOI: 10.1016/j.alcohol.2008.03.128 |
0.462 |
|
2008 |
Leggio L, Addolorato G. Serotonin transporter (SERT) brain density and neurobiological Cloninger subtypes model: a lesson by human autoradiography studies. Alcohol and Alcoholism (Oxford, Oxfordshire). 43: 148-50. PMID 18211952 DOI: 10.1093/alcalc/agm169 |
0.558 |
|
2008 |
Leggio L, Kenna GA, Swift RM. New developments for the pharmacological treatment of alcohol withdrawal syndrome. A focus on non-benzodiazepine GABAergic medications. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1106-17. PMID 18029075 DOI: 10.1016/j.pnpbp.2007.09.021 |
0.482 |
|
2007 |
Abenavoli L, Bardazzi G, Cracolici F, Quaranta C, Santini G, Graziosi S, Polero L, Leggio L, Addolorato G. Complementary therapies for treating alcoholism First Annual meeting by Complementary Medicine Research Group of the Italian Society for Alcohol Studies-May 5, 2006, Florence, Italy. Fitoterapia. 79: 142-7. PMID 18187264 DOI: 10.1016/j.fitote.2007.11.016 |
0.498 |
|
2007 |
Addolorato G, Leggio L, Ferrulli A, Cardone S, Vonghia L, Mirijello A, Abenavoli L, D'Angelo C, Caputo F, Zambon A, Haber PS, Gasbarrini G. Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study. Lancet (London, England). 370: 1915-22. PMID 18068515 DOI: 10.1016/S0140-6736(07)61814-5 |
0.458 |
|
2007 |
Addolorato G, Leggio L, Agabio R, Colombo G, Gasbarrini G. Baclofen: a new drug for the treatment of alcohol dependence. International Journal of Clinical Practice. 60: 1003-8. PMID 16893442 DOI: 10.1111/j.1742-1241.2006.01065.x |
0.539 |
|
2006 |
Addolorato G, Capristo E, Leggio L, Ferrulli A, Abenavoli L, Malandrino N, Farnetti S, Domenicali M, D'Angelo C, Vonghia L, Mirijello A, Cardone S, Gasbarrini G. Relationship between ghrelin levels, alcohol craving, and nutritional status in current alcoholic patients. Alcoholism, Clinical and Experimental Research. 30: 1933-7. PMID 17067359 DOI: 10.1111/J.1530-0277.2006.00238.X |
0.513 |
|
2006 |
Bardazzi G, Merluzzi JA, Voller F, Fontana A, Abenavoli L, Leggio L, Addolorato G. Complementary medicine for alcohol dependence in Italian services: a mail questionnaire. Complementary Therapies in Clinical Practice. 12: 216-21. PMID 16835034 DOI: 10.1016/J.CTCP.2005.12.003 |
0.44 |
|
2006 |
Ferrulli A, Leggio L, Abenavoli L, Farnetti S, Malandrino N, D'Angelo C, Vonghia L, Mirijello A, Cardone S, Leso V, Domenicali M, Caputo F, Bernardi M, Stefanini G, Capristo E, et al. Ghrelin in alcohol-dependent patients and correlation with nutritional status and craving Digestive and Liver Disease. 38: S160. DOI: 10.1016/S1590-8658(06)80433-0 |
0.482 |
|
2006 |
Leggio L, Abenavoli L, Ferrulli A, Agabio R, D'Angelo C, Vonghia L, Mirijello A, Malandrino N, Cardone S, Capristo E, Caputo F, Bernardi M, Stefanini G, Colombo G, Gessa G, et al. Baclofen in the treatment of alcohol withdrawal syndrome: A randomized comparative study versus diazepam Digestive and Liver Disease. 38: S96. DOI: 10.1016/S1590-8658(06)80257-4 |
0.457 |
|
2005 |
Addolorato G, Leggio L, Abenavoli L, Gasbarrini G. Neurobiochemical and clinical aspects of craving in alcohol addiction: a review. Addictive Behaviors. 30: 1209-24. PMID 15925129 DOI: 10.1016/J.ADDBEH.2004.12.011 |
0.424 |
|
2005 |
Leggio L, Abenavoli L, Caputo F, Gasbarrini G, Addolorato G. Baclofen use in the treatment of alcohol delirium tremens. Archives of Internal Medicine. 165: 586; author reply 58. PMID 15767538 DOI: 10.1001/ARCHINTE.165.5.586-A |
0.513 |
|
2005 |
Addolorato G, Abenavoli L, Leggio L, Gasbarrini G. How many cravings? Pharmacological aspects of craving treatment in alcohol addiction: a review. Neuropsychobiology. 51: 59-66. PMID 15741745 DOI: 10.1159/000084161 |
0.45 |
|
2005 |
Addolorato G, Leggio L, Abenavoli L, Caputo F, Gasbarrini G. Baclofen for outpatient treatment of alcohol withdrawal syndrome. The Journal of Family Practice. 54: 24. PMID 15623403 |
0.462 |
|
2004 |
Addolorato G, Leggio L, Abenavoli L, Caputo F, Gasbarrini G. Tolerance to baclofen's sedative effect in alcohol-addicted patients: no dissipation after a period of abstinence. Psychopharmacology. 178: 351-2. PMID 15719231 DOI: 10.1007/s00213-004-2014-4 |
0.493 |
|
2003 |
Addolorato G, Leggio L, Abenavoli L, DeLorenzi G, Parente A, Caputo F, Janiri L, Capristo E, Rapaccini GL, Gasbarrini G. Suppression of alcohol delirium tremens by baclofen administration: a case report. Clinical Neuropharmacology. 26: 258-62. PMID 14520166 DOI: 10.1097/00002826-200309000-00010 |
0.441 |
|
Low-probability matches (unlikely to be authored by this person) |
2021 |
Shah NN, Schwandt ML, Hobden B, Baldwin DS, Sinclair J, Agabio R, Leggio L. The validity of the state-trait anxiety inventory and the brief scale for anxiety in an inpatient sample with alcohol use disorder. Addiction (Abingdon, England). PMID 33861887 DOI: 10.1111/add.15516 |
0.296 |
|
2018 |
Litten RZ, Falk DE, Ryan ML, Fertig J, Leggio L. Advances in Pharmacotherapy Development: Human Clinical Studies. Handbook of Experimental Pharmacology. PMID 29294197 DOI: 10.1007/164_2017_79 |
0.296 |
|
2022 |
Farokhnia M, Fede SJ, Grodin EN, Browning BD, Crozier ME, Schwandt ML, Hodgkinson CA, Momenan R, Leggio L. Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use. Scientific Reports. 12: 13027. PMID 35906358 DOI: 10.1038/s41598-022-17190-3 |
0.291 |
|
2011 |
Edwards S, Kenna GA, Swift RM, Leggio L. Current and promising pharmacotherapies, and novel research target areas in the treatment of alcohol dependence: a review. Current Pharmaceutical Design. 17: 1323-32. PMID 21524263 DOI: 10.2174/138161211796150765 |
0.279 |
|
2023 |
Teng PN, Barakat W, Tran SM, Tran ZM, Bateman NW, Conrads KA, Wilson KN, Oliver J, Gist G, Hood BL, Zhou M, Maxwell GL, Leggio L, Conrads TP, Lee MR. Brain proteomic atlas of alcohol use disorder in adult males. Translational Psychiatry. 13: 318. PMID 37833300 DOI: 10.1038/s41398-023-02605-0 |
0.272 |
|
2018 |
de Beaurepaire R, Sinclair JMA, Heydtmann M, Addolorato G, Aubin HJ, Beraha EM, Caputo F, Chick JD, de La Selle P, Franchitto N, Garbutt JC, Haber PS, Jaury P, Lingford-Hughes AR, Morley KC, ... ... Leggio L, et al. The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective. Frontiers in Psychiatry. 9: 708. PMID 30662411 DOI: 10.3389/Fpsyt.2018.00708 |
0.264 |
|
2020 |
Ray LA, Grodin EN, Leggio L, Bechtholt AJ, Becker H, Feldstein Ewing SW, Jentsch JD, King AC, Mason BJ, O'Malley S, MacKillop J, Heilig M, Koob GF. The future of translational research on alcohol use disorder. Addiction Biology. e12903. PMID 32286721 DOI: 10.1111/Adb.12903 |
0.263 |
|
2017 |
Zallar LJ, Farokhnia M, Tunstall BJ, Vendruscolo LF, Leggio L. The Role of the Ghrelin System in Drug Addiction. International Review of Neurobiology. 136: 89-119. PMID 29056157 DOI: 10.1016/bs.irn.2017.08.002 |
0.255 |
|
2008 |
Leggio L, Ferrulli A, Malandrino N, Miceli A, Capristo E, Gasbarrini G, Addolorato G. Insulin but not insulin growth factor-1 correlates with craving in currently drinking alcohol-dependent patients. Alcoholism, Clinical and Experimental Research. 32: 450-8. PMID 18215216 DOI: 10.1111/j.1530-0277.2007.00589.x |
0.253 |
|
2007 |
Addolorato G, Leggio L, Ojetti V, Capristo E, Gasbarrini G, Gasbarrini A. Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males. Appetite. 50: 50-6. PMID 17602789 DOI: 10.1016/j.appet.2007.05.008 |
0.25 |
|
2017 |
Hobden B, Schwandt ML, Carey M, Lee MR, Farokhnia M, Bouhlal S, Oldmeadow C, Leggio L. The Validity of the Montgomery-Asberg Depression Rating Scale in an Inpatient Sample with Alcohol Dependence. Alcoholism, Clinical and Experimental Research. PMID 28421616 DOI: 10.1111/Acer.13400 |
0.239 |
|
2006 |
Addolorato G, Leggio L, Abenavoli L, Agabio R, Caputo F, Capristo E, Colombo G, Gessa GL, Gasbarrini G. Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam. The American Journal of Medicine. 119: 276.e13-8. PMID 16490478 DOI: 10.1016/j.amjmed.2005.08.042 |
0.229 |
|
2021 |
Arab JP, Izzy M, Leggio L, Bataller R, Shah VH. Management of alcohol use disorder in patients with cirrhosis in the setting of liver transplantation. Nature Reviews. Gastroenterology & Hepatology. PMID 34725498 DOI: 10.1038/s41575-021-00527-0 |
0.226 |
|
2019 |
Leggio L, Falk DE, Ryan ML, Fertig J, Litten RZ. Medication Development for Alcohol Use Disorder: A Focus on Clinical Studies. Handbook of Experimental Pharmacology. PMID 31628604 DOI: 10.1007/164_2019_295 |
0.223 |
|
2021 |
Morley K, Perry CJ, Watt J, Hurzeler T, Leggio L, Lawrence AJ, Haber P. New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies. Expert Opinion On Pharmacotherapy. PMID 33615945 DOI: 10.1080/14656566.2021.1892641 |
0.219 |
|
2012 |
Kenna GA, Roder-Hanna N, Leggio L, Zywiak WH, Clifford J, Edwards S, Kenna JA, Shoaff J, Swift RM. Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy. Pharmacogenomics and Personalized Medicine. 5: 19-35. PMID 23226060 DOI: 10.2147/PGPM.S23462 |
0.2 |
|
2015 |
Thanos PK, Michaelides M, Subrize M, Miller ML, Bellezza R, Cooney RN, Leggio L, Wang GJ, Rogers AM, Volkow ND, Hajnal A. Roux-en-Y Gastric Bypass Alters Brain Activity in Regions that Underlie Reward and Taste Perception. Plos One. 10: e0125570. PMID 26039080 DOI: 10.1371/Journal.Pone.0125570 |
0.198 |
|
2017 |
Kahler CW, Cioe PA, Tzilos GK, Spillane NS, Leggio L, Ramsey SE, Brown RA, O'Malley SS. A Double-Blind Randomized Placebo-Controlled Trial of Oral Naltrexone for Heavy Drinking Smokers Seeking Smoking Cessation Treatment. Alcoholism, Clinical and Experimental Research. PMID 28401564 DOI: 10.1111/acer.13396 |
0.19 |
|
2015 |
Ghareeb M, Leggio L, El-Kattan A, Akhlaghi F. Development and validation of an UPLC-MS/MS assay for quantitative analysis of the ghrelin receptor inverse agonist PF-5190457 in human or rat plasma and rat brain. Analytical and Bioanalytical Chemistry. 407: 5603-13. PMID 25943263 DOI: 10.1007/S00216-015-8730-2 |
0.18 |
|
2018 |
Li G, Ji G, Hu Y, Liu L, Jin Q, Zhang W, Liu L, Wang Y, Zhao J, von Deneen KM, Chen A, Cui G, Han Y, Wang H, Zhao Q, ... ... Leggio L, et al. Reduced plasma ghrelin concentrations are associated with decreased brain reactivity to food cues after laparoscopic sleeve gastrectomy. Psychoneuroendocrinology. 100: 229-236. PMID 30388597 DOI: 10.1016/J.Psyneuen.2018.10.022 |
0.17 |
|
2019 |
Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31182423 DOI: 10.1124/Dmd.119.087015 |
0.167 |
|
2017 |
Diana M, Raij T, Melis M, Nummenmaa A, Leggio L, Bonci A. Rehabilitating the addicted brain with transcranial magnetic stimulation. Nature Reviews. Neuroscience. PMID 28951609 DOI: 10.1038/Nrn.2017.113 |
0.161 |
|
2020 |
Farokhnia M, McDiarmid GR, Newmeyer MN, Munjal V, Abulseoud OA, Huestis MA, Leggio L. Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study. Translational Psychiatry. 10: 71. PMID 32075958 DOI: 10.1038/s41398-020-0756-3 |
0.155 |
|
2019 |
Adusumalli S, Jamwal R, Leggio L, Akhlaghi F. Development and validation of an assay for a novel ghrelin receptor inverse agonist PF-5190457 and its major hydroxy metabolite (PF-6870961) by LC-MS/MS in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1130: 121820. PMID 31670107 DOI: 10.1016/J.Jchromb.2019.121820 |
0.154 |
|
2021 |
Hersey M, Bacon AK, Bailey LG, Coggiano MA, Newman AH, Leggio L, Tanda G. Psychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap? Frontiers in Neuroscience. 15: 656475. PMID 34121988 DOI: 10.3389/fnins.2021.656475 |
0.148 |
|
2017 |
Haass-Koffler CL, Goodyear K, Long VM, Tran HH, Loche A, Cacciaglia R, Swift RM, Leggio L. A Phase I randomized clinical trial testing the safety, tolerability and preliminary pharmacokinetics of the mGluR5 negative allosteric modulator GET 73 following single and repeated doses in healthy volunteers. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28778464 DOI: 10.1016/j.ejps.2017.07.031 |
0.148 |
|
2018 |
Zallar LJ, Tunstall BJ, Richie CT, Zhang YJ, You ZB, Gardner EL, Heilig M, Pickel J, Koob GF, Vendruscolo LF, Harvey BK, Leggio L. Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model. International Journal of Obesity (2005). PMID 29453460 DOI: 10.1038/S41366-018-0013-5 |
0.144 |
|
2022 |
You ZB, Gardner EL, Galaj E, Moore AR, Buck T, Jordan CJ, Humburg BA, Bi GH, Xi ZX, Leggio L. Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches. Molecular Psychiatry. PMID 35064236 DOI: 10.1038/s41380-022-01438-5 |
0.144 |
|
2022 |
Perelló M, Dickson SL, Zigman JM, Leggio L. Toward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor. Journal of Neuroendocrinology. e13224. PMID 36580314 DOI: 10.1111/jne.13224 |
0.137 |
|
2013 |
Lee MR, Bollinger JW, Leggio L. Increased Ethanol Consumption Following Chronic Psychosocial Stress: Do Oxytocin and Baclofen Hold any Therapeutic Promise? Frontiers in Psychiatry. 4: 148. PMID 24298259 DOI: 10.3389/fpsyt.2013.00148 |
0.135 |
|
2021 |
Heilig M, MacKillop J, Martinez D, Rehm J, Leggio L, Vanderschuren LJMJ. Addiction as a brain disease revised: why it still matters, and the need for consilience. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33619327 DOI: 10.1038/s41386-020-00950-y |
0.131 |
|
2022 |
Deschaine SL, Leggio L. From "Hunger Hormone" to "It's Complicated": Ghrelin Beyond Feeding Control. Physiology (Bethesda, Md.). 37: 5-15. PMID 34964687 DOI: 10.1152/physiol.00024.2021 |
0.131 |
|
2022 |
Hersey M, Bacon AK, Bailey LG, Lee MR, Chen AY, Leggio L, Tanda G. Oxytocin Receptors Mediate Oxytocin Potentiation of Methylphenidate-Induced Stimulation of Accumbens Dopamine in Rats. Journal of Neurochemistry. PMID 36420597 DOI: 10.1111/jnc.15730 |
0.127 |
|
2019 |
Lee MR, Rohn MCH, Zanettini C, Coggiano MA, Leggio L, Tanda G. Effect of systemically administered oxytocin on dose response for methylphenidate self-administration and mesolimbic dopamine levels. Annals of the New York Academy of Sciences. PMID 31074517 DOI: 10.1111/nyas.14101 |
0.127 |
|
2019 |
Wenthur CJ, Gautam R, Zhou B, Vendruscolo LF, Leggio L, Janda KD. Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin. Scientific Reports. 9: 1841. PMID 30755699 DOI: 10.1038/S41598-019-38549-Z |
0.126 |
|
2023 |
Browning BD, Kirkland AE, Green R, Engevik M, Alekseyenko AV, Leggio L, Tomko RL, Squeglia LM. The adolescent and young adult microbiome and its association with substance use: a scoping review. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 37665023 DOI: 10.1093/alcalc/agad055 |
0.124 |
|
2024 |
Aminesmaeili M, Farokhnia M, Susukida R, Leggio L, Johnson RM, Crum RM, Mojtabai R. Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials. Addiction (Abingdon, England). PMID 38197836 DOI: 10.1111/add.16409 |
0.12 |
|
2020 |
Lee MR, Shnitko TA, Blue SW, Kaucher AV, Winchell AJ, Erikson DW, Grant KA, Leggio L. Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques. Nature Communications. 11: 2783. PMID 32494001 DOI: 10.1038/S41467-020-15942-1 |
0.118 |
|
2022 |
Nicolas C, Zlebnik NE, Farokhnia M, Leggio L, Ikemoto S, Shaham Y. Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review. Pharmacological Reviews. 74: 119-140. PMID 34987089 DOI: 10.1124/pharmrev.121.000367 |
0.117 |
|
2018 |
Lee MR, Sheskier MB, Farokhnia M, Feng N, Marenco S, Lipska BK, Leggio L. Oxytocin receptor mRNA expression in dorsolateral prefrontal cortex in major psychiatric disorders: A human post-mortem study. Psychoneuroendocrinology. 96: 143-147. PMID 29940428 DOI: 10.1016/j.psyneuen.2018.05.039 |
0.116 |
|
2014 |
Mellion ML, Silbermann E, Gilchrist JM, Machan JT, Leggio L, de la Monte S. Small-fiber degeneration in alcohol-related peripheral neuropathy. Alcoholism, Clinical and Experimental Research. 38: 1965-72. PMID 24961481 DOI: 10.1111/Acer.12470 |
0.115 |
|
2010 |
Fenton M, Leggio L, Kenna GA, Swift RM. HIV testing in hazardous drinking: a survey analysis. Substance Use & Misuse. 45: 204-12. PMID 20025448 DOI: 10.3109/10826080902882839 |
0.114 |
|
2014 |
Malandrino N, Miceli A, Leggio L, Mingrone G, Capristo E. High ghrelin levels in post-treatment euthyroid patients with Hashimoto's thyroiditis: a case-control preliminary study. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 122: 540-3. PMID 24918532 DOI: 10.1055/s-0034-1376965 |
0.112 |
|
2017 |
Rohsenow DJ, Tidey JW, Martin RA, Colby SM, Swift RM, Leggio L, Monti PM. Varenicline versus Nicotine Patch with Brief Advice for Smokers with Substance Use Disorders with or without Depression: Effects on Smoking, Substance Use and Depressive Symptoms. Addiction (Abingdon, England). PMID 28498504 DOI: 10.1111/Add.13861 |
0.108 |
|
2017 |
Bouhlal S, Ellefsen KN, Sheskier MB, Singley E, Pirard S, Gorelick DA, Huestis MA, Leggio L. Acute effects of intravenous cocaine administration on serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and relationships with cardiorespiratory and subjective responses. Drug and Alcohol Dependence. 180: 68-75. PMID 28881319 DOI: 10.1016/J.Drugalcdep.2017.07.033 |
0.105 |
|
2020 |
Eiden LE, Goosens KA, Jacobson KA, Leggio L, Zhang L. Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics. Acs Pharmacology & Translational Science. 3: 190-202. PMID 32296762 DOI: 10.1021/acsptsci.0c00017 |
0.102 |
|
2021 |
Piacentino D, Sani G, Kotzalidis GD, Cappelletti S, Longo L, Rizzato S, Fabi F, Frati P, Fineschi V, Leggio L. Anabolic androgenic steroids used as performance and image enhancing drugs in professional and amateur athletes: Toxicological and psychopathological findings. Human Psychopharmacology. e2815. PMID 34528289 DOI: 10.1002/hup.2815 |
0.102 |
|
2023 |
Pietrzak M, Yngve A, Hamilton JP, Kämpe R, Boehme R, Asratian A, Gauffin E, Löfberg A, Gustavson S, Persson E, Capusan AJ, Leggio L, Perini I, Tinghög G, Heilig M. A randomized controlled experimental medicine study of ghrelin in value-based decision making. The Journal of Clinical Investigation. PMID 37040196 DOI: 10.1172/JCI168260 |
0.101 |
|
2008 |
Malandrino N, Capristo E, Farnetti S, Leggio L, Abenavoli L, Addolorato G, Gasbarrini G. Metabolic and nutritional features in adult celiac patients. Digestive Diseases (Basel, Switzerland). 26: 128-33. PMID 18431062 DOI: 10.1159/000116770 |
0.1 |
|
2017 |
Lee MR, Scheidweiler KB, Diao XX, Akhlaghi F, Cummins A, Huestis MA, Leggio L, Averbeck BB. Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay. Molecular Psychiatry. PMID 28289281 DOI: 10.1038/Mp.2017.27 |
0.099 |
|
2005 |
Abenavoli L, Leggio L, Di Giuda D, Gasbarrini G, Addolorato G. Neurologic disorders in patients with celiac disease: are they mediated by brain perfusion changes? Pediatrics. 114: 1734; author reply 1. PMID 15574641 DOI: 10.1542/peds.2004-1248 |
0.094 |
|
2008 |
Malandrino N, Leggio L, Addolorato G, Gasbarrini G, Capristo E. Link between insulin and metabolic disorders in cancer: does leptin play a key role? Breast Cancer Research and Treatment. 115: 435-6. PMID 18561022 DOI: 10.1007/s10549-008-0091-5 |
0.094 |
|
2020 |
Sadighi A, Leggio L, Akhlaghi F. Development of a Physiologically Based Pharmacokinetic Model for Prediction of Ethanol Concentration-Time Profile in Different Organs. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 33316031 DOI: 10.1093/alcalc/agaa129 |
0.093 |
|
2017 |
Martinotti G, Montemitro C, Baroni G, Andreoli S, Alimonti F, Di Nicola M, Tonioni F, Leggio L, di Giannantonio M, Janiri L. Relationship between craving and plasma leptin concentrations in patients with cocaine addiction. Psychoneuroendocrinology. 85: 35-41. PMID 28806585 DOI: 10.1016/j.psyneuen.2017.08.004 |
0.091 |
|
1998 |
Postorino A, Vetri T, Leggio L, Serio R, Bonvissuto F. Nitric oxide as neuromodulator of sympathetic transmission in rat vas deferens. Journal of Autonomic Pharmacology. 18: 21-9. PMID 9728322 DOI: 10.1046/J.1365-2680.1998.1810021.X |
0.09 |
|
2021 |
Weng HY, Feldman JL, Leggio L, Napadow V, Park J, Price CJ. Interventions and Manipulations of Interoception. Trends in Neurosciences. 44: 52-62. PMID 33378657 DOI: 10.1016/j.tins.2020.09.010 |
0.09 |
|
2012 |
Leggio L. S.15.04 Role of baclofen and modulation at GABAB receptor in treating addiction: a clinical prospective European Neuropsychopharmacology. 22: S133-S134. DOI: 10.1016/S0924-977X(12)70168-2 |
0.085 |
|
2007 |
Leggio L, Ferrulli A, Mirijello A, Abenavoli L, Di Giuda D, Funiciello S, Rotoli M, Gasbarrini G, Addolorato G. Penicillamine-related lichenoid dermatitis and utility of zinc acetate in a Wilson disease patient with hepatic presentation, anxiety and SPECT abnormalities. International Journal of Immunopathology and Pharmacology. 20: 185-90. PMID 17346443 DOI: 10.1177/039463200702000122 |
0.084 |
|
2015 |
Terraneo A, Leggio L, Saladini M, Ermani M, Bonci A, Gallimberti L. Transcranial magnetic stimulation of dorsolateral prefrontal cortex reduces cocaine use: A pilot study. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26655188 DOI: 10.1016/j.euroneuro.2015.11.011 |
0.083 |
|
2008 |
Addolorato G, Leggio L, D'Angelo C, Mirijello A, Ferrulli A, Cardone S, Vonghia L, Abenavoli L, Leso V, Nesci A, Piano S, Capristo E, Gasbarrini G. Affective and psychiatric disorders in celiac disease. Digestive Diseases (Basel, Switzerland). 26: 140-8. PMID 18431064 DOI: 10.1159/000116772 |
0.083 |
|
2004 |
Leggio L, Abenavoli L, D'Angelo C, Di Giuda D, Gasbarrini G, Addolorato G. Gluten-related cerebral hypoperfusion and neurologic disorders in coeliac patients. Alimentary Pharmacology & Therapeutics. 20: 821-2; author reply . PMID 15379843 DOI: 10.1111/j.1365-2036.2004.02167.x |
0.082 |
|
2022 |
Leggio L, Jung MK. The Need for Integrating Addiction Medicine and Hepatology. Jama Network Open. 5: e2213022. PMID 35594051 DOI: 10.1001/jamanetworkopen.2022.13022 |
0.076 |
|
2008 |
Leggio L, Cadoni G, D'Angelo C, Mirijello A, Scipione S, Ferrulli A, Agostino S, Paludetti G, Gasbarrini G, Addolorato G. Coeliac disease and hearing loss: preliminary data on a new possible association. Scandinavian Journal of Gastroenterology. 42: 1209-13. PMID 17852854 DOI: 10.1080/00365520701327377 |
0.075 |
|
2021 |
Navarro G, Rea W, Quiroz C, Moreno E, Gomez D, Wenthur CJ, Casadó V, Leggio L, Hearing MC, Ferré S. Complexes of ghrelin GHS-R1a, GHS-R1b and dopamine D receptors localized in the ventral tegmental area as main mediators of the dopaminergic effects of ghrelin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34876469 DOI: 10.1523/JNEUROSCI.1151-21.2021 |
0.075 |
|
2018 |
Pettorruso M, Spagnolo PA, Leggio L, Janiri L, Di Giannantonio M, Gallimberti L, Bonci A, Martinotti G. Repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex may improve symptoms of anhedonia in individuals with cocaine use disorder: A pilot study. Brain Stimulation. PMID 29885861 DOI: 10.1016/J.Brs.2018.06.001 |
0.072 |
|
2005 |
Leggio L, Abenavoli L, Gasbarrini G, Addolorato G. Psychological support counseling: a new strategy to increase gluten-free diet compliance in celiac patients. The American Journal of Gastroenterology. 100: 1424-5. PMID 15929784 DOI: 10.1111/J.1572-0241.2005.41929_6.X |
0.07 |
|
2004 |
Addolorato G, De Lorenzi G, Abenavoli L, Leggio L, Capristo E, Gasbarrini G. Psychological support counselling improves gluten-free diet compliance in coeliac patients with affective disorders. Alimentary Pharmacology & Therapeutics. 20: 777-82. PMID 15379838 DOI: 10.1111/j.1365-2036.2004.02193.x |
0.07 |
|
2003 |
Addolorato G, Parente A, de Lorenzi G, D'angelo Di Paola ME, Abenavoli L, Leggio L, Capristo E, De Simone C, Rotoli M, Rapaccini GL, Gasbarrini G. Rapid regression of psoriasis in a coeliac patient after gluten-free diet. A case report and review of the literature. Digestion. 68: 9-12. PMID 12949434 DOI: 10.1159/000073220 |
0.07 |
|
2017 |
Haass-Koffler CL, Goodyear K, Long VM, Tran HH, Loche A, Cacciaglia R, Swift RM, Leggio L. Dataset for Phase I randomized clinical trial for safety and tolerability of GET 73 in single and repeated ascending doses including preliminary pharmacokinetic parameters. Data in Brief. 15: 407-413. PMID 29214202 DOI: 10.1016/j.dib.2017.09.018 |
0.069 |
|
2009 |
Capristo E, Malandrino N, Farnetti S, Mingrone G, Leggio L, Addolorato G, Gasbarrini G. Increased serum high-density lipoprotein-cholesterol concentration in celiac disease after gluten-free diet treatment correlates with body fat stores. Journal of Clinical Gastroenterology. 43: 946-9. PMID 19809359 DOI: 10.1097/MCG.0b013e3181978e4d |
0.068 |
|
2021 |
Deschaine SL, Leggio L. Understanding plasma treatment effect on human acyl-ghrelin concentrations. European Review For Medical and Pharmacological Sciences. 24: 1585-1589. PMID 32096210 DOI: 10.26355/eurrev_202002_20216 |
0.067 |
|
2008 |
Abenavoli L, Proietti I, Vonghia L, Leggio L, Ferrulli A, Capizzi R, Mirijello A, Cardone S, Malandrino N, Leso V, Rotoli M, Amerio PL, Gasbarrini G, Addolorato G. Intestinal malabsorption and skin diseases. Digestive Diseases (Basel, Switzerland). 26: 167-74. PMID 18431067 DOI: 10.1159/000116775 |
0.066 |
|
2008 |
D'Angelo C, Mirijello A, Leggio L, Ferrulli A, Carotenuto V, Icolaro N, Miceli A, D'Angelo V, Gasbarrini G, Addolorato G. State and trait anxiety and depression in patients with primary brain tumors before and after surgery: 1-year longitudinal study. Journal of Neurosurgery. 108: 281-6. PMID 18240923 DOI: 10.3171/JNS/2008/108/2/0281 |
0.065 |
|
2005 |
Addolorato G, Leggio L, Abenavoli L, Gasbarrini G, Caputo F, Vignoli T, Lorenzini F, Bernardi M. Gamma hydroxybutyrric acid (GHB) withdrawal does not occur at therapeutic dosage. Drug and Alcohol Dependence. 77: 209. PMID 15664723 DOI: 10.1016/J.DRUGALCDEP.2004.09.003 |
0.065 |
|
2005 |
Leggio L, Addolorato G, Abenavoli L, Gasbarrini G. Wilson's disease: clinical, genetic and pharmacological findings. International Journal of Immunopathology and Pharmacology. 18: 7-14. PMID 15698506 DOI: 10.1177/039463200501800102 |
0.064 |
|
2017 |
Terraneo A, Leggio L, Saladinie M, Ermanie M, Bonci A, Gallimberti L. Dorsolateral prefrontal cortex TMS reduces cocaine use: A pilot study Brain Stimulation. 10: 483-484. DOI: 10.1016/j.brs.2017.01.417 |
0.062 |
|
2021 |
Heilig M, MacKillop J, Martinez D, Rehm J, Leggio L, Vanderschuren LJMJ. Response to "Addiction is a social disease: just as tenable as calling it a brain disease". Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34108632 DOI: 10.1038/s41386-021-01037-y |
0.06 |
|
2021 |
You ZB, Galaj E, Alén F, Wang B, Bi GH, Moore AR, Buck T, Crissman M, Pari S, Xi ZX, Leggio L, Wise RA, Gardner EL. Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34923576 DOI: 10.1038/s41386-021-01249-2 |
0.06 |
|
2019 |
Pisanu C, Franconi F, Gessa GL, Mameli S, Pisanu GM, Campesi I, Leggio L, Agabio R. Sex differences in the response to opioids for pain relief: A systematic review and meta-analysis. Pharmacological Research. 148: 104447. PMID 31499196 DOI: 10.1016/j.phrs.2019.104447 |
0.059 |
|
2018 |
Pupo DA, Kakareka JW, Krynitsky J, Leggio L, Pohida T, Studenski S, Harvey BK. Reliability of a Novel Video-Based Method for Assessing Age-Related Changes in Upper Limb Kinematics. Frontiers in Aging Neuroscience. 10: 281. PMID 30319392 DOI: 10.3389/Fnagi.2018.00281 |
0.058 |
|
2007 |
Abenavoli L, Leggio L, Proietti I, Ferrulli A, Vonghia L, D'Angelo C, Mirijello A, Capizzi R, Rotoli M, Amerio P, Gasbarrini G, Addolorato G. [The skin as a mirror of small intestine]. Recenti Progressi in Medicina. 98: 339-46. PMID 17580527 |
0.056 |
|
2021 |
Himelein-Wachowiak M, Giorgi S, Devoto A, Rahman M, Ungar L, Schwartz HA, Epstein DH, Leggio L, Curtis B. Bots and misinformation spread on social media: A mixed scoping review with implications for COVID-19. Journal of Medical Internet Research. PMID 33882014 DOI: 10.2196/26933 |
0.056 |
|
2007 |
Leggio L, Malandrino N, Loudianos G, Abenavoli L, Lepori MB, Capristo E, De Virgiliis S, Gasbarrini G, Addolorato G. Analysis of the T1288R mutation of the Wilson disease ATP7B gene in four generations of a family: possible genotype-phenotype correlation with hepatic onset. Digestive Diseases and Sciences. 52: 2570-5. PMID 17410460 DOI: 10.1007/s10620-006-9666-3 |
0.053 |
|
2006 |
Leggio L, Abenavoli L, Parente A, de Lorenzi G, Gasbarrini G, Addolorato G. Celiac disease and skin disorders. Pediatric Dermatology. 22: 376-7. PMID 16060887 DOI: 10.1111/j.1525-1470.2005.22426.x |
0.052 |
|
2016 |
Creed M, Bonci A, Leggio L. Modulating Morphine Context-Induced Drug Memory With Deep Brain Stimulation: More Research Questions by Lowering Stimulation Frequencies? Biological Psychiatry. 80: 647-649. PMID 27697154 DOI: 10.1016/J.Biopsych.2016.08.022 |
0.051 |
|
2008 |
Leggio L, Abenavoli L, Vonghia L, Perrone L, Niccoli G, Fusco B, Gui D, Bonomo L, Donti A, Di Bartolomeo R, Gasbarrini G, Addolorato G. Superior vena cava thrombosis treated by angioplasty and stenting in a cirrhotic patient with peritoneovenous shunt. Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia. 14: 60-2. PMID 18292745 |
0.05 |
|
2017 |
Farokhnia M, Momenan R, Leggio L. Commentary on Schmitz et al. (2017): Advancing medication development for addiction-behavioral and neuroimaging outcomes as indirect biomarkers of target engagement. Addiction (Abingdon, England). 112: 1869-1870. PMID 28891145 DOI: 10.1111/add.13959 |
0.049 |
|
2009 |
Leggio L, Addolorato G. "Do you want a vodka? No, a green tea please!" Epigallocatechin gallate and its possible role in oxidative stress and liver damage. Nutrition (Burbank, Los Angeles County, Calif.). 25: 1-2. PMID 18834722 DOI: 10.1016/j.nut.2008.07.011 |
0.049 |
|
2006 |
Abenavoli L, Proietti L, Leggio L, Ferrulli A, Vonghia L, Capizzi R, Rotoli M, Amerio PL, Gasbarrini G, Addolorato G. Cutaneous manifestations in celiac disease World Journal of Gastroenterology. 12: 843-852. PMID 16521210 DOI: 10.3748/WJG.V12.I6.843 |
0.048 |
|
2006 |
Leggio L, Addolorato G, Loudianos G, Abenavoli L, Lepori MB, Vecchio FM, Rapaccini GL, De Virgiliis S, Gasbarrini G. A new mutation of Wilson's disease P-type ATPase gene in a patient with cirrhosis and coombs-positive hemolytic anemia. Digestive Diseases and Sciences. 51: 34-8. PMID 16416207 DOI: 10.1007/s10620-006-3080-8 |
0.048 |
|
2010 |
Leso V, Leggio L, Armuzzi A, Gasbarrini G, Gasbarrini A, Addolorato G. Role of the tumor necrosis factor antagonists in the treatment of inflammatory bowel disease: an update. European Journal of Gastroenterology & Hepatology. 22: 779-86. PMID 19786877 DOI: 10.1097/MEG.0b013e328331b654 |
0.045 |
|
2008 |
Addolorato G, Mirijello A, D'Angelo C, Leggio L, Ferrulli A, Vonghia L, Cardone S, Leso V, Miceli A, Gasbarrini G. Social phobia in coeliac disease. Scandinavian Journal of Gastroenterology. 43: 410-5. PMID 18365905 DOI: 10.1080/00365520701768802 |
0.042 |
|
2010 |
D'Angelo C, Mirijello A, Ferrulli A, Leggio L, Berardi A, Icolaro N, Miceli A, D'Angelo V, Gasbarrini G, Addolorato G. Role of trait anxiety in persistent radicular pain after surgery for lumbar disc herniation: a 1-year longitudinal study. Neurosurgery. 67: 265-71. PMID 20644411 DOI: 10.1227/01.NEU.0000371971.51755.1C |
0.041 |
|
2005 |
Abenavoli L, Leggio L, Ferrulli A, Vonghia L, Gasbarrini G, Addolorato G. Association between psoriasis and coeliac disease. The British Journal of Dermatology. 152: 1393-4. PMID 15949032 DOI: 10.1111/j.1365-2133.2005.06636.x |
0.038 |
|
2007 |
Abenavoli L, Leggio L, Gasbarrini G, Addolorato G. [Evaluation of liver fibrosis in clinical practice]. Recenti Progressi in Medicina. 97: 481-5. PMID 17017301 |
0.035 |
|
2008 |
Addolorato G, Mirijello A, D'Angelo C, Leggio L, Ferrulli A, Abenavoli L, Vonghia L, Cardone S, Leso V, Cossari A, Capristo E, Gasbarrini G. State and trait anxiety and depression in patients affected by gastrointestinal diseases: psychometric evaluation of 1641 patients referred to an internal medicine outpatient setting. International Journal of Clinical Practice. 62: 1063-9. PMID 18422970 DOI: 10.1111/j.1742-1241.2008.01763.x |
0.031 |
|
2009 |
Leggio L, Addolorato G, Loudianos G, Abenavoli L, Gasbarrini G. Genotype-phenotype correlation of the Wilson disease ATP7B gene. American Journal of Medical Genetics. Part A. 140: 933. PMID 16532467 DOI: 10.1002/ajmg.a.31191 |
0.029 |
|
2006 |
Leggio L, Addolorato G, Parker S, Gasbarrini G, Tanner S. Wilson's disease: Creating a european clinical database and designing randomised controlled clinical trials Digestive and Liver Disease. 38: S188. DOI: 10.1016/S1590-8658(06)80509-8 |
0.028 |
|
2006 |
Abenavoli L, Ferrulli A, Leggio L, Vonghia L, D'Angelo C, Mirijello A, De Maria V, Giancotti F, De Siena M, Abenavoli S, Addolorato G, Gasbarrini G. Improvement of primary biliary cirrhosis in a patient affected by coeliac disease and Hp infection: A case report Digestive and Liver Disease. 38: S183-S184. DOI: 10.1016/S1590-8658(06)80496-2 |
0.026 |
|
2021 |
Dionisi T, Sestito L, Tarli C, Antonelli M, Tosoni A, D'Addio S, Mirijello A, Vassallo GA, Leggio L, Gasbarrini A, Addolorato G. Risk of burnout and stress in physicians working in a COVID team: A longitudinal survey. International Journal of Clinical Practice. e14755. PMID 34449957 DOI: 10.1111/ijcp.14755 |
0.026 |
|
2007 |
Abenavoli L, Leggio L, Gasbarrini G, Addolorato G. Celiac disease and skin: psoriasis association. World Journal of Gastroenterology. 13: 2138-9. PMID 17465464 DOI: 10.3748/WJG.V13.I14.2138 |
0.025 |
|
2007 |
Leggio L, Gasbarrini G, Addolorato G. Wilson's disease. Lancet (London, England). 369: 902. PMID 17368142 DOI: 10.1016/S0140-6736(07)60437-1 |
0.023 |
|
2007 |
Cadoni G, Scipione S, Agostino S, Addolorato G, Cianfrone F, Leggio L, Paludetti G, Lippa S. Coenzyme Q 10 and cardiovascular risk factors in idiopathic sudden sensorineural hearing loss patients. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 28: 878-83. PMID 17558340 DOI: 10.1097/MAO.0b013e3180686e4a |
0.021 |
|
2006 |
Leggio L, Abenavoli L, D'Angelo C, Ferrulli A, Vonghia L, Mirijello A, Barbarino R, De Michele T, Zuppi C, Gui D, Rapaccini GL, Gasbarrini G, Addolorato G. Marked decrease of serum Ca 125 levels after Denver shunt placement in a patient with cirrhosis and refractory ascites. Digestive Diseases and Sciences. 51: 1644-6. PMID 16927135 DOI: 10.1007/s10620-006-9115-3 |
0.021 |
|
2006 |
Leggio L, Addolorato G, Abenavoli L, Ferrulli A, D'Angelo C, Mirijello A, Vonghia L, Schinzari G, Arena V, Perrone L, Citterio F, Bonomo L, Rapaccini GL, Capelli A, Barone C, et al. Primary renal angiosarcoma: a rare malignancy. A case report and review of the literature. Urologic Oncology. 24: 307-12. PMID 16818182 DOI: 10.1016/J.UROLONC.2005.10.002 |
0.02 |
|
2013 |
Mirijello A, Addolorato G, D'Angelo C, Ferrulli A, Vassallo G, Antonelli M, Leggio L, Landolfi R. Baclofen in the treatment of persistent hiccup: a case series. International Journal of Clinical Practice. 67: 918-21. PMID 23834241 DOI: 10.1111/ijcp.12184 |
0.017 |
|
2018 |
Trychta KA, Heathward EJ, Sulima A, Bäck S, Farokhnia M, Richie CT, Leggio L, Rice KC, Harvey BK. Extracellular esterase activity as an indicator of endoplasmic reticulum calcium depletion. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 1-10. PMID 30095301 DOI: 10.1080/1354750X.2018.1490968 |
0.015 |
|
2020 |
Leggio L, Chick J. From 'The Red Journal', for the Retirement of Editor-in-Chief Philippe De Witte: A Fond and Grateful Farewell. Alcohol and Alcoholism (Oxford, Oxfordshire). 55: 1-2. PMID 31994695 DOI: 10.1093/alcalc/agaa008 |
0.013 |
|
2008 |
Leggio L. Primary angiosarcoma of the kidney: size is the main prognostic factor. International Journal of Urology : Official Journal of the Japanese Urological Association. 14: 777; author reply 77. PMID 17681076 DOI: 10.1111/j.1442-2042.2007.01785.x |
0.01 |
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