Matthias Hediger - Publications

Affiliations: 
Institute of Biochemistry and Molecular Medicine Harvard University, Cambridge, MA, United States 

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gyimesi G, Hediger MA. Transporter-Mediated Drug Delivery. Molecules (Basel, Switzerland). 28. PMID 36770817 DOI: 10.3390/molecules28031151  0.344
2021 Pujol-Giménez J, Poirier M, Bühlmann S, Schuppisser C, Bhardwaj R, Awale M, Visini R, Javor S, Hediger MA, Reymond JL. Inhibitors of human divalent metal transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB-17 fragment library. Chemmedchem. PMID 34309203 DOI: 10.1002/cmdc.202100467  0.328
2021 Havukainen S, Pujol-Giménez J, Valkonen M, Westerholm-Parvinen A, Hediger MA, Landowski CP. Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei. Scientific Reports. 11: 14678. PMID 34282161 DOI: 10.1038/s41598-021-93552-7  0.384
2021 Gyimesi G, Hediger MA. SLC66 Lysosomal amino acid transporters in GtoPdb v.2021.2 Iuphar/Bps Guide to Pharmacology Cite. 2021. DOI: 10.2218/gtopdb/f1048/2021.2  0.388
2020 Gyimesi G, Pujol-Giménez J, Kanai Y, Hediger MA. Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application. Pflugers Archiv : European Journal of Physiology. 472: 1177-1206. PMID 32767111 DOI: 10.1007/s00424-020-02433-x  0.347
2019 Manatschal C, Pujol-Giménez J, Poirier M, Reymond JL, Hediger MA, Dutzler R. Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds. Elife. 8. PMID 31804182 DOI: 10.7554/eLife.51913  0.401
2019 Lüscher BP, Surbek DV, Clémençon B, Huang X, Albrecht C, Marini C, Hediger MA, Baumann MU. Different Pharmacological Properties of GLUT9a and GLUT9b: Potential Implications in Preeclampsia. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 53: 508-517. PMID 31502429 DOI: 10.33594/000000154  0.336
2019 Gyimesi G, Albano G, Fuster DG, Hediger MA, Pujol-Giménez J. Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). The Journal of Biological Chemistry. PMID 30914478 DOI: 10.1074/jbc.RA118.006113  0.347
2019 Trotti D, Rolfs A, Danbolt NC, Brown RH, Hediger MA. SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter Nature Neuroscience. 2: 848. PMID 10461226 DOI: 10.1038/12227  0.326
2018 Kandasamy P, Gyimesi G, Kanai Y, Hediger MA. Amino acid transporters revisited: New views in health and disease. Trends in Biochemical Sciences. PMID 30177408 DOI: 10.1016/j.tibs.2018.05.003  0.346
2018 Franz MC, Pujol-Gimenez J, Montalbetti N, Fernandez-Tenorio M, DeGrado TR, Niggli E, Romero MF, Hediger MA. Reassessment of the transport mechanism of the human zinc transporter SLC39A2. Biochemistry. PMID 29791142 DOI: 10.1021/Acs.Biochem.8B00511  0.418
2017 Pujol-Giménez J, Hediger MA, Gyimesi G. A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters. Scientific Reports. 7: 6194. PMID 28754960 DOI: 10.1038/s41598-017-06446-y  0.365
2017 Lüscher BP, Marini C, Joerger-Messerli MS, Huang X, Hediger MA, Albrecht C, Baumann MU, Surbek DV. Placental glucose transporter (GLUT)-1 is down-regulated in preeclampsia. Placenta. 55: 94-99. PMID 28623979 DOI: 10.1016/j.placenta.2017.04.023  0.32
2016 Leuenberger M, Ritler A, Simonin A, Hediger MA, Lochner M. Concise Asymmetric Synthesis and Pharmacological Characterization of All Stereoisomers of Glutamate Transporter Inhibitor TFB-TBOA and Synthesis of EAAT Photoaffinity Probes. Acs Chemical Neuroscience. 7: 534-9. PMID 26918289 DOI: 10.1021/acschemneuro.5b00311  0.349
2016 marini c, Lüscher BP, Joerger-Messerli M, Huang X, Albrecht C, Hediger MA, Surbek DV, Baumann MU. 505: Down-regulation of placental glucose transporter (GLUT)-1 in pre-eclampsia American Journal of Obstetrics and Gynecology. 214: S275. DOI: 10.1016/J.AJOG.2015.10.548  0.352
2015 Simonin A, Montalbetti N, Gyimesi G, Pujol-Giménez J, Hediger MA. The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2. The Journal of Biological Chemistry. 290: 30464-74. PMID 26483543 DOI: 10.1074/jbc.M115.689836  0.455
2015 Dhayat N, Simonin A, Anderegg M, Pathare G, Lüscher BP, Deisl C, Albano G, Mordasini D, Hediger MA, Surbek DV, Vogt B, Sass JO, Kloeckener-Gruissem B, Fuster DG. Mutation in the Monocarboxylate Transporter 12 Gene Affects Guanidinoacetate Excretion but Does Not Cause Glucosuria. Journal of the American Society of Nephrology : Jasn. PMID 26376857 DOI: 10.1681/Asn.2015040411  0.4
2015 César-Razquin A, Snijder B, Frappier-Brinton T, Isserlin R, Gyimesi G, Bai X, Reithmeier RA, Hepworth D, Hediger MA, Edwards AM, Superti-Furga G. A Call for Systematic Research on Solute Carriers. Cell. 162: 478-87. PMID 26232220 DOI: 10.1016/J.Cell.2015.07.022  0.323
2015 Montalbetti N, Simonin A, Simonin C, Awale M, Reymond JL, Hediger MA. Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2. Biochemical Pharmacology. 96: 216-24. PMID 26047847 DOI: 10.1016/j.bcp.2015.05.002  0.345
2015 Lüscher BP, Baumann MU, Marini C, Hediger MA, Albrecht C, Stieger B, Surbek DV. Expression and function of placental uric acid transporter GLUT9 Placenta. 36: A55. DOI: 10.1016/J.PLACENTA.2015.07.352  0.412
2015 Marini C, Lüscher BP, Jörger-Messerli M, Huang X, Gertsch J, Hediger MA, Albrecht C, Surbek DV, Baumann MU. Down-regulation of placental glucose transporter (GLUT)-1 in pre-eclampsia Placenta. 36: A54. DOI: 10.1016/J.PLACENTA.2015.07.350  0.352
2015 Lüscher B, Marini C, Huang X, Albrecht C, Hediger M, Stieger B, Surbek D, Baumann M. 292: Placental urate transport is GLUT9-mediated and unidirectional American Journal of Obstetrics and Gynecology. 212. DOI: 10.1016/J.Ajog.2014.10.338  0.513
2015 Marini C, Lüscher B, Joerger-Messerli M, Sager R, Huang X, Albrecht C, Hediger M, Gertsch J, Baumann M, Surbek D. 136: Placental glucose transporter (GLUT)-1 is functionally down-regulated in pre-eclampsia American Journal of Obstetrics and Gynecology. 212. DOI: 10.1016/J.Ajog.2014.10.182  0.452
2014 Clémençon B, Lüscher BP, Fine M, Baumann MU, Surbek DV, Bonny O, Hediger MA. Expression, purification, and structural insights for the human uric acid transporter, GLUT9, using the Xenopus laevis oocytes system. Plos One. 9: e108852. PMID 25286413 DOI: 10.1371/journal.pone.0108852  0.41
2014 Franz MC, Simonin A, Graeter S, Hediger MA, Kovacs G. Development of the First Fluorescence Screening Assay for the SLC39A2 Zinc Transporter. Journal of Biomolecular Screening. 19: 909-916. PMID 24619115 DOI: 10.1177/1087057114526781  0.376
2014 Montalbetti N, Dalghi MG, Albrecht C, Hediger MA. Nutrient transport in the mammary gland: calcium, trace minerals and water soluble vitamins. Journal of Mammary Gland Biology and Neoplasia. 19: 73-90. PMID 24567109 DOI: 10.1007/s10911-014-9317-9  0.394
2014 Montalbetti N, Simonin A, Dalghi MG, Kovacs G, Hediger MA. Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra. Journal of Biomolecular Screening. 19: 900-908. PMID 24505080 DOI: 10.1177/1087057114521663  0.314
2014 Lüscher BP, Fine M, Marini C, Clemençon B, Albrecht C, Hediger MA, Surbek DV, Baumann MU. Placental uric acid transporter GLUT9 is modulated by free iodine Placenta. 35: A97. DOI: 10.1016/J.PLACENTA.2014.06.314  0.386
2014 Marini C, Lüscher BP, Jörger-Messerli M, Sager R, Huang X, Gertsch J, Hediger MA, Albrecht C, Baumann MU, Surbek DV. Placental glucose transporter (GLUT)-1 regulation in pre-eclampsia Placenta. 35: A83-A84. DOI: 10.1016/J.PLACENTA.2014.06.269  0.352
2013 Boggavarapu R, Jeckelmann JM, Harder D, Schneider P, Ucurum Z, Hediger M, Fotiadis D. Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). Plos One. 8: e76427. PMID 24124560 DOI: 10.1371/Journal.Pone.0076427  0.366
2013 Bürzle M, Suzuki Y, Ackermann D, Miyazaki H, Maeda N, Clémençon B, Burrier R, Hediger MA. The sodium-dependent ascorbic acid transporter family SLC23. Molecular Aspects of Medicine. 34: 436-54. PMID 23506882 DOI: 10.1016/J.Mam.2012.12.002  0.445
2013 Smith DE, Clémençon B, Hediger MA. Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. Molecular Aspects of Medicine. 34: 323-36. PMID 23506874 DOI: 10.1016/j.mam.2012.11.003  0.311
2013 Bergeron MJ, Clémençon B, Hediger MA, Markovich D. SLC13 family of Na⁺-coupled di- and tri-carboxylate/sulfate transporters. Molecular Aspects of Medicine. 34: 299-312. PMID 23506872 DOI: 10.1016/j.mam.2012.12.001  0.43
2013 Kanai Y, Clémençon B, Simonin A, Leuenberger M, Lochner M, Weisstanner M, Hediger MA. The SLC1 high-affinity glutamate and neutral amino acid transporter family. Molecular Aspects of Medicine. 34: 108-20. PMID 23506861 DOI: 10.1016/j.mam.2013.01.001  0.435
2013 Hediger MA, Clémençon B, Burrier RE, Bruford EA. The ABCs of membrane transporters in health and disease (SLC series): introduction. Molecular Aspects of Medicine. 34: 95-107. PMID 23506860 DOI: 10.1016/j.mam.2012.12.009  0.343
2013 Lüscher BP, Clémençon B, Surbeck DV, Huang X, Marini C, Hediger MA, Albrecht C, Baumann M. Placental uric acid transport system Placenta. 34: A95. DOI: 10.1016/j.placenta.2013.06.282  0.407
2013 Marini C, Lüscher BP, Surbek DV, Messerli M, Sager R, Albrecht C, Hediger MA, Baumann M. Placental Glucose Transporter GLUT1 Expression in Pre-eclampsia Placenta. 34: A88. DOI: 10.1016/J.PLACENTA.2013.06.262  0.36
2013 Lüscher B, Baumann M, Messerli M, Surbek D, Marini C, Sager R, Albrecht C, Hediger M. 639: Down-regulation of placental glucose transporter 1 in preeclampsia American Journal of Obstetrics and Gynecology. 208. DOI: 10.1016/J.Ajog.2012.10.805  0.456
2012 Bürzle M, Hediger MA. Functional and physiological role of vitamin C transporters. Current Topics in Membranes. 70: 357-75. PMID 23177992 DOI: 10.1016/B978-0-12-394316-3.00011-9  0.393
2012 Tschopp F, Baumann M, Messerli M, Sager R, Albrecht C, Hediger M, Surbek D. 213: Expression of glucose transporter (GLUT)-1 and -9 in placental tissue American Journal of Obstetrics and Gynecology. 206. DOI: 10.1016/J.Ajog.2011.10.231  0.443
2011 Bergeron MJ, Boggavarapu R, Meury M, Ucurum Z, Caron L, Isenring P, Hediger MA, Fotiadis D. Frog oocytes to unveil the structure and supramolecular organization of human transport proteins Plos One. 6. PMID 21760919 DOI: 10.1371/journal.pone.0021901  0.319
2011 Bergeron MJ, Bürzle M, Kovacs G, Simonin A, Hediger MA. Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B. The Journal of Biological Chemistry. 286: 11242-53. PMID 21257749 DOI: 10.1074/jbc.M110.171728  0.337
2010 Dutzler R, Ernstb B, Hediger MA, Keppler D, Mohr P, Neidhart W, Märki HP. Channels and transporters. Mini-symposium of the Division of Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS) at the Department of Chemistry, University of Basel, May 27, 2010. Chimia. 64: 662-6. PMID 21138110  0.304
2010 Luethi E, Nguyen KT, Bürzle M, Blum LC, Suzuki Y, Hediger M, Reymond JL. Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). Journal of Medicinal Chemistry. 53: 7236-50. PMID 20812729 DOI: 10.1021/Jm100959G  0.4
2008 Bergeron MJ, Simonin A, Bürzle M, Hediger MA. Inherited epithelial transporter disorders--an overview. Journal of Inherited Metabolic Disease. 31: 178-87. PMID 18415698 DOI: 10.1007/s10545-008-0861-6  0.411
2008 Benn BS, Ajibade D, Porta A, Dhawan P, Hediger M, Peng JB, Jiang Y, Oh GT, Jeung EB, Lieben L, Bouillon R, Carmeliet G, Christakos S. Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology. 149: 3196-205. PMID 18325990 DOI: 10.1210/En.2007-1655  0.302
2008 Mackenzie B, Illing AC, Hediger MA. Transport model of the human Na+-coupled L-ascorbic acid (vitamin C) transporter SVCT1. American Journal of Physiology. Cell Physiology. 294: C451-9. PMID 18094143 DOI: 10.1152/Ajpcell.00439.2007  0.635
2008 Mackenzie B, Hediger MA, Varoqui H. Mechanisms of the system a neuronal glutamine transporter SAT1 Journal of Neurochemistry. 81: 72-72. DOI: 10.1046/J.1471-4159.2002.00073.X  0.655
2008 Landowski CP, Suzuki Y, Hediger MA. The Mammalian Transporter Families Seldin and Giebisch's the Kidney. 91-146. DOI: 10.1016/B978-012088488-9.50007-3  0.305
2007 Mackenzie B, Takanaga H, Hubert N, Rolfs A, Hediger MA. Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). The Biochemical Journal. 403: 59-69. PMID 17109629 DOI: 10.1042/Bj20061290  0.608
2007 Balakrishnan A, Tavakkolizadeh A, Hediger M, Takanaga H, Rhoads D, Ashley SW. P45: Diurnal rhythmicity of ileal transporter expression Journal of Surgical Research. 137: 2-6. DOI: 10.1016/J.Jss.2006.12.272  0.424
2007 Landowski CP, Suzuki Y, Hediger MA. Transporters for excitatory and neutral amino acids Handbook of Neurochemistry and Molecular Neurobiology: Neural Membranes and Transport. 305-323. DOI: 10.1007/978-0-387-30380-2_15  0.465
2006 Berger UV, Hediger MA. Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs. Anatomy and Embryology. 211: 595-606. PMID 16868771 DOI: 10.1007/s00429-006-0109-x  0.318
2006 Mackenzie B, Ujwal ML, Chang MH, Romero MF, Hediger MA. Divalent metal-ion transporter DMT1 mediates both H+ -coupled Fe2+ transport and uncoupled fluxes. Pflã¼Gers Archiv : European Journal of Physiology. 451: 544-58. PMID 16091957 DOI: 10.1007/S00424-005-1494-3  0.569
2005 Takanaga H, Mackenzie B, Peng JB, Hediger MA. Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain. Biochemical and Biophysical Research Communications. 337: 892-900. PMID 16226721 DOI: 10.1016/J.Bbrc.2005.09.128  0.63
2005 Hediger MA, Johnson RJ, Miyazaki H, Endou H. Molecular physiology of urate transport. Physiology (Bethesda, Md.). 20: 125-33. PMID 15772301 DOI: 10.1152/physiol.00039.2004  0.318
2005 Takanaga H, Mackenzie B, Suzuki Y, Hediger MA. Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. The Journal of Biological Chemistry. 280: 8974-84. PMID 15632147 DOI: 10.1074/Jbc.M413027200  0.684
2004 Marciani P, Trotti D, Hediger MA, Monticelli G. Modulation of DMT1 Activity by Redox Compounds Journal of Membrane Biology. 197: 91-99. PMID 15014911 DOI: 10.1007/s00232-003-0644-9  0.62
2004 Kanai Y, Hediger MA. The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflugers Archiv : European Journal of Physiology. 447: 469-79. PMID 14530974 DOI: 10.1007/s00424-003-1146-4  0.445
2004 Mackenzie B, Hediger MA. SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1. Pflã¼Gers Archiv : European Journal of Physiology. 447: 571-9. PMID 14530973 DOI: 10.1007/S00424-003-1141-9  0.571
2004 Takanaga H, Mackenzie B, Hediger MA. Sodium-dependent ascorbic acid transporter family SLC23. Pflã¼Gers Archiv : European Journal of Physiology. 447: 677-82. PMID 12845532 DOI: 10.1007/S00424-003-1104-1  0.618
2003 Kanai Y, Hediger MA. The glutamate and neutral amino acid transporter family: physiological and pharmacological implications. European Journal of Pharmacology. 479: 237-47. PMID 14612154  0.439
2003 Mackenzie B, Schäfer MK, Erickson JD, Hediger MA, Weihe E, Varoqui H. Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons. The Journal of Biological Chemistry. 278: 23720-30. PMID 12684517 DOI: 10.1074/Jbc.M212718200  0.653
2003 Liu Z, Stevens BR, Feldman DH, Hediger MA, Harvey WR. K+ amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity. The Journal of Experimental Biology. 206: 245-54. PMID 12477895 DOI: 10.1242/jeb.00065  0.444
2002 Hediger MA, Rolfs A, Goswami T. Iron transport and hemochromatosis. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 50: 239S-246S. PMID 12227653 DOI: 10.2310/6650.2002.32964  0.301
2001 Trotti D, Peng JB, Dunlop J, Hediger MA. Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters Brain Research. 914: 196-203. PMID 11578612 DOI: 10.1016/S0006-8993(01)02802-5  0.671
2001 Rolfs A, Hediger MA. Intestinal metal ion absorption: an update. Current Opinion in Gastroenterology. 17: 177-183. PMID 11224676  0.36
2001 Trotti D, Aoki M, Pasinelli P, Berger UV, Danbolt NC, Brown RH, Hediger MA. Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity Journal of Biological Chemistry. 276: 576-582. PMID 11031254 DOI: 10.1074/Jbc.M003779200  0.682
2001 Sacchi VF, Castagna M, Trotti D, Shayakul C, Hediger MA. Neutral amino acid absorption in the midgut of lepidopteran larvae Advances in Insect Physiology. 28: 168-184. DOI: 10.1016/S0065-2806(01)28010-2  0.617
2001 Merlin D, Si-Tahar M, Sitaraman SV, Eastburn K, Williams I, Hediger M, Madara JL. hPepT1 expeession occurs in chronic colitis and related transport of bacterial peptides influences expression of class 1 molecules Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)83470-1  0.349
2000 Yao D, Mackenzie B, Ming H, Varoqui H, Zhu H, Hediger MA, Erickson JD. A novel system A isoform mediating Na+/neutral amino acid cotransport. The Journal of Biological Chemistry. 275: 22790-7. PMID 10811809 DOI: 10.1074/Jbc.M002965200  0.637
2000 Wang Y, Mackenzie B, Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA. Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochemical and Biophysical Research Communications. 267: 488-94. PMID 10631088 DOI: 10.1006/Bbrc.1999.1929  0.621
1999 Hediger MA. Glutamate transporters in kidney and brain. The American Journal of Physiology. 277: F487-92. PMID 10516270 DOI: 10.1152/ajprenal.1999.277.4.F487  0.369
1999 Hediger MA, Welbourne TC. Introduction: glutamate transport, metabolism, and physiological responses. The American Journal of Physiology. 277: F477-80. PMID 10516268 DOI: 10.1152/ajprenal.1999.277.4.F477  0.405
1999 Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA. A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature. 399: 70-5. PMID 10331392 DOI: 10.1038/19986  0.651
1999 Trotti D, Rolfs A, Danbolt NC, Brown RH, Hediger MA. SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter Nature Neuroscience. 2: 427-433. PMID 10321246 DOI: 10.1038/8091  0.619
1998 Romero MF, Fong P, Berger UV, Hediger MA, Boron WF. Cloning and functional expression of rNBC, an electrogenic Na-[Formula: see text]cotransporter from rat kidney. American Journal of Physiology. Renal Physiology. 274: F425-F432. PMID 29592596 DOI: 10.1152/ajprenal.1998.274.2.F425  0.31
1998 Tsukaguchi H, Shayakul C, Berger UV, Hediger MA. Urea transporters in kidney: molecular analysis and contribution to the urinary concentrating process. American Journal of Physiology. Renal Physiology. 275: F319-F324. PMID 29591680 DOI: 10.1152/ajprenal.1998.275.3.F319  0.331
1998 Steel A, Hediger MA. The Molecular Physiology of Sodium- and Proton-Coupled Solute Transporters. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 13: 123-131. PMID 11390775  0.335
1998 Merlin D, Steel A, Gewirtz AT, Si-Tahar M, Hediger MA, Madara JL. hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions. The Journal of Clinical Investigation. 102: 2011-8. PMID 9835627 DOI: 10.1172/Jci4179  0.367
1998 Estévez R, Camps M, Rojas AM, Testar X, Devés R, Hediger MA, Zorzano A, Palacín M. The amino acid transport system y+L/4F2hc is a heteromultimeric complex. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1319-29. PMID 9761775 DOI: 10.1096/fasebj.12.13.1319  0.344
1998 Castagna M, Shayakul C, Trotti D, Sacchi VF, Harvey WR, Hediger MA. Cloning and characterization of a potassium-coupled amino acid transporter. Proceedings of the National Academy of Sciences of the United States of America. 95: 5395-400. PMID 9560287 DOI: 10.1073/pnas.95.9.5395  0.685
1998 Romero MF, Fong P, Berger UV, Hediger MA, Boron WF. Cloning and functional expression of rNBC, an electrogenic Na+-HCO3/- cotransporter from rat kidney American Journal of Physiology - Renal Physiology. 274: F425-F432. PMID 9486238 DOI: 10.1152/Ajprenal.1998.274.2.F425  0.346
1997 Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA. Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. American Journal of Physiology. Renal Physiology. 273: F1023-F1029. PMID 29586122 DOI: 10.1152/ajprenal.1997.273.6.F1023  0.357
1997 Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA. Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. The American Journal of Physiology. 273: F1023-9. PMID 9435692 DOI: 10.1152/Ajprenal.1997.273.6.F1023  0.358
1997 Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, Hediger MA. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature. 388: 482-8. PMID 9242408 DOI: 10.1038/41343  0.562
1997 Shayakul C, Knepper MA, Smith CP, DiGiovanni SR, Hediger MA. Segmental localization of urea transporter mRNAs in rat kidney. The American Journal of Physiology. 272: F654-60. PMID 9176377 DOI: 10.1152/ajprenal.1997.272.5.F654  0.323
1997 Romero MF, Hediger MA, Boulpaep EL, Boron WF. Expression cloning and characterization of a renal electrogenic Na+/HCO3 - cotransporter Nature. 387: 409-413. PMID 9163427 DOI: 10.1038/387409A0  0.468
1997 Tsukaguchi H, Shayakul C, Berger UV, Tokui T, Brown D, Hediger MA. Cloning and characterization of the urea transporter UT3: localization in rat kidney and testis. Journal of Clinical Investigation. 99: 1506-1515. PMID 9119994 DOI: 10.1172/Jci119313  0.335
1997 Steel A, Nussberger S, Romero MF, Boron WF, Boyd CA, Hediger MA. Stoichiometry and pH dependence of the rabbit proton-dependent oligopeptide transporter PepT1. The Journal of Physiology. 498: 563-9. PMID 9051570 DOI: 10.1113/Jphysiol.1997.Sp021883  0.346
1997 Castagna M, Shayakul C, Trotti D, Sacchi VF, Harvey WR, Hediger MA. Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis. Journal of Experimental Biology. 200: 269-286. DOI: 10.1242/JEB.200.2.269  0.5
1996 Nussberger S, Foret F, Hebert SC, Karger BL, Hediger MA. Nonradioactive monitoring of organic and inorganic solute transport into single Xenopus oocytes by capillary zone electrophoresis Biophysical Journal. 70: 998-1005. PMID 8789117  0.422
1996 Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, Kanai Y, Hediger MA, Wang Y, Schielke JP, Welty DF. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron. 16: 675-86. PMID 8785064 DOI: 10.1016/S0896-6273(00)80086-0  0.371
1996 Hediger MA, Smith CP, You G, Lee WS, Kanai Y, Shayakul C. Structure, regulation and physiological roles of urea transporters. Kidney International. 49: 1615-23. PMID 8743465 DOI: 10.1038/KI.1996.235  0.38
1995 Liu W, Liang R, Ramamoorthy S, Fei YJ, Ganapathy ME, Hediger MA, Ganapathy V, Leibach FH. Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney. Biochimica Et Biophysica Acta. 1235: 461-6. PMID 7756356 DOI: 10.1016/0005-2736(95)80036-F  0.323
1995 Hediger MA, Kanai Y, You G, Nussberger S. Mammalian ion‐coupled solute transporters The Journal of Physiology. 482: 7-17. PMID 7730974 DOI: 10.1113/jphysiol.1995.sp020559  0.488
1995 Kanai Y, Nussberger S, Romero MF, Boron WF, Hebert SC, Hediger MA. Electrogenic properties of the epithelial and neuronal high affinity glutamate transporter Journal of Biological Chemistry. 270: 16561-16568. PMID 7622462 DOI: 10.1074/Jbc.270.28.16561  0.463
1994 Kanai Y, Lee WS, You G, Brown D, Hediger MA. The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. Journal of Clinical Investigation. 93: 397-404. PMID 8282810 DOI: 10.1172/Jci116972  0.337
1994 Fei YJ, Kanai Y, Nussberger S, Ganapathy V, Leibach FH, Romero MF, Singh SK, Boron WF, Hediger MA. Expression cloning of a mammalian proton-coupled oligopeptide transporter Nature. 368: 563-566. PMID 8139693 DOI: 10.1038/368563A0  0.413
1994 Burant CF, Flink S, DePaoli AM, Chen J, Lee WS, Hediger MA, Buse JB, Chang EB. Small intestine hexose transport in experimental diabetes. Increased transporter mRNA and protein expression in enterocytes. The Journal of Clinical Investigation. 93: 578-85. PMID 8113395 DOI: 10.1172/JCI117010  0.31
1994 Hediger MA, Rhoads DB. Molecular physiology of sodium-glucose cotransporters Physiological Reviews. 74: 993-1026. PMID 7938229 DOI: 10.1152/PHYSREV.1994.74.4.993  0.438
1994 Kanai Y, Smith CP, Hediger MA. A new family of neurotransmitter transporters: the high-affinity glutamate transporters. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 1450-9. PMID 7903261 DOI: 10.1096/fasebj.7.15.7903261  0.345
1994 Dyer DL, Kanai Y, Hediger MA, Rubin SA, Said HM. Expression of a rabbit renal ascorbic acid transporter in Xenopus laevis oocytes American Journal of Physiology - Cell Physiology. 267. PMID 7519399 DOI: 10.1152/AJPCELL.1994.267.1.C301  0.425
1994 Hediger MA, Kanai Y. Expression cloning and characterization of the glutamate transporter in neurons. Renal Physiology and Biochemistry. 17: 161-4. PMID 7518948 DOI: 10.1159/000173808  0.337
1993 Lee WS, Wells RG, Sabbag RV, Mohandas TK, Hediger MA. Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport. The Journal of Clinical Investigation. 91: 1959-63. PMID 8486766 DOI: 10.1172/JCI116415  0.305
1993 Gamba G, Saltzberg SN, Lombardi M, Miyanoshita A, Lytton J, Hediger MA, Brenner BM, Hebert SC. Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter Proceedings of the National Academy of Sciences of the United States of America. 90: 2749-2753. PMID 8464884  0.367
1993 You G, Smith CP, Kanai Y, Lee WS, Stelzner M, Hediger MA. Cloning and characterization of the vasopressin-regulated urea transporter. Nature. 365: 844-7. PMID 8413669 DOI: 10.1038/365844A0  0.394
1993 Kanai Y, Smith CP, Hediger MA. The elusive transporters with a high affinity for glutamate. Trends in Neurosciences. 16: 365-70. PMID 7694407 DOI: 10.1016/0166-2236(93)90094-3  0.419
1993 Kanai Y, Stelzner MG, Lee WS, Wells RG, Brown D, Hediger MA. Expression of mRNA (D2) encoding a protein involved in amino acid transport in S3 proximal tubule. The American Journal of Physiology. 263: F1087-92. PMID 1481885 DOI: 10.1152/AJPRENAL.1992.263.6.F1087  0.375
1992 Wells RG, Lee WS, Kanai Y, Leiden JM, Hediger MA. The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes. The Journal of Biological Chemistry. 267: 15285-8. PMID 1639774  0.346
1992 Wells RG, Pajor AM, Kanai Y, Turk E, Wright EM, Hediger MA. Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter. The American Journal of Physiology. 263: F459-65. PMID 1415574 DOI: 10.1152/Ajprenal.1992.263.3.F459  0.599
1992 Wells RG, Hediger MA. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases. Proceedings of the National Academy of Sciences of the United States of America. 89: 5596-600. PMID 1376924 DOI: 10.1073/PNAS.89.12.5596  0.404
1992 Kanai Y, Hediger MA. Primary structure and functional characterization of a high-affinity glutamate transporter. Nature. 360: 467-71. PMID 1280334 DOI: 10.1038/360467A0  0.422
1991 Hediger MA, Mendlein J, Lee HS, Wright EM. Biosynthesis of the cloned intestinal Na+/glucose cotransporter. Biochimica Et Biophysica Acta. 1064: 360-4. PMID 1903656 DOI: 10.1016/0005-2736(91)90323-Z  0.523
1991 Hirayama BA, Wong HC, Smith CD, Hagenbuch BA, Hediger MA, Wright EM. Intestinal and renal Na+/glucose cotransporters share common structures. The American Journal of Physiology. 261: C296-304. PMID 1714681 DOI: 10.1152/Ajpcell.1991.261.2.C296  0.484
1990 Birnir B, Lee HS, Hediger MA, Wright EM. Expression and characterization of the intestinal Na+/glucose cotransporter in COS-7 cells. Biochimica Et Biophysica Acta. 1048: 100-4. PMID 2105101 DOI: 10.1016/0167-4781(90)90028-Z  0.557
1989 Ikeda TS, Hwang ES, Coady MJ, Hirayama BA, Hediger MA, Wright EM. Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine. The Journal of Membrane Biology. 110: 87-95. PMID 2795642 DOI: 10.1007/Bf01870995  0.555
1989 Hediger MA, Budarf ML, Emanuel BS, Mohandas TK, Wright EM. Assignment of the human intestinal Na+/glucose cotransporter gene (SGLT1) to the q11.2 → qter region of chromosome 22 Genomics. 4: 297-300. PMID 2714793 DOI: 10.1016/0888-7543(89)90333-9  0.444
1989 Wright EM, Hediger MA, Coady MJ, Hirayama B, Turk E. Molecular biology of Na+/glucose cotransport. Biochemical Society Transactions. 17: 810-1. PMID 2695358 DOI: 10.1042/Bst0170810  0.47
1989 Hediger MA, Turk E, Pajor AM, Wright EM. Molecular genetics of the human Na+/glucose cotransporter. Klinische Wochenschrift. 67: 843-6. PMID 2681963 DOI: 10.1007/Bf01717337  0.55
1989 Hediger MA, Turk E, Wright EM. Homology of the human intestinal Na+/glucose and Escherichia coli Na+/proline cotransporters. Proceedings of the National Academy of Sciences of the United States of America. 86: 5748-52. PMID 2490366 DOI: 10.1073/Pnas.86.15.5748  0.573
1987 Hediger MA, Ikeda T, Coady M, Gundersen CB, Wright EM. Expression of size-selected mRNA encoding the intestinal Na/glucose cotransporter in Xenopus laevis oocytes. Proceedings of the National Academy of Sciences of the United States of America. 84: 2634-7. PMID 3472228 DOI: 10.1073/Pnas.84.9.2634  0.531
1987 Hediger MA, Coady MJ, Ikeda TS, Wright EM. Expression cloning and cDNA sequencing of the Na+/glucose co-transporter Nature. 330: 379-381. PMID 2446136 DOI: 10.1038/330379A0  0.626
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