| Year |
Citation |
Score |
| 2019 |
Titunick MB, Lewis GS, Cain JD, Zagon IS, McLaughlin PJ. Blockade of the OGF-OGFr pathway in diabetic bone. Connective Tissue Research. 1-9. PMID 30931654 DOI: 10.1080/03008207.2019.1593396 |
0.375 |
|
| 2018 |
Zagon IS, McLaughlin PJ. Intermittent blockade of OGFr and treatment of autoimmune disorders. Experimental Biology and Medicine (Maywood, N.J.). 1535370218817746. PMID 30541348 DOI: 10.1177/1535370218817746 |
0.336 |
|
| 2018 |
Ludwig MD, Zagon IS, McLaughlin PJ. Modulation of the OGF-OGFr pathway alters cytokine profiles in experimental autoimmune encephalomyelitis and multiple sclerosis. Experimental Biology and Medicine (Maywood, N.J.). 1535370217749830. PMID 29307283 DOI: 10.1177/1535370217749830 |
0.372 |
|
| 2018 |
Cain JD, Titunick M, McLaughlin P, Zagon I. Effects of Local Opioid Antagonist on Diabetic Fracture Rat Model Foot & Ankle Orthopaedics. 3: 2473011418S0017. DOI: 10.1177/2473011418S00178 |
0.346 |
|
| 2017 |
McLaughlin PJ, Cain JD, Titunick MB, Sassani JW, Zagon IS. Topical Naltrexone Is a Safe and Effective Alternative to Standard Treatment of Diabetic Wounds. Advances in Wound Care. 6: 279-288. PMID 28894635 DOI: 10.1089/Wound.2016.0725 |
0.345 |
|
| 2017 |
Ludwig MD, Zagon IS, McLaughlin PJ. Serum [Met(5)]-enkephalin levels are reduced in multiple sclerosis and restored by low-dose naltrexone. Experimental Biology and Medicine (Maywood, N.J.). 1535370217724791. PMID 28766982 DOI: 10.1177/1535370217724791 |
0.398 |
|
| 2017 |
Ludwig MD, Zagon IS, McLaughlin PJ. Elevated serum [Met(5)]-enkephalin levels correlate with improved clinical and behavioral outcomes in experimental autoimmune encephalomyelitis. Brain Research Bulletin. PMID 28647454 DOI: 10.1016/J.Brainresbull.2017.06.015 |
0.305 |
|
| 2016 |
Sassani JW, Mc Laughlin PJ, Zagon IS. The Yin and Yang of the Opioid Growth Regulatory System: Focus on Diabetes-The Lorenz E. Zimmerman Tribute Lecture. Journal of Diabetes Research. 2016: 9703729. PMID 27703986 DOI: 10.1155/2016/9703729 |
0.453 |
|
| 2015 |
Kren NP, Zagon IS, McLaughlin PJ. Nuclear export of opioid growth factor receptor is CRM1 dependent. Experimental Biology and Medicine (Maywood, N.J.). PMID 26429201 DOI: 10.1177/1535370215605585 |
0.364 |
|
| 2015 |
Hammer LA, Waldner H, Zagon IS, McLaughlin PJ. Opioid growth factor and low-dose naltrexone impair central nervous system infiltration by CD4 + T lymphocytes in established experimental autoimmune encephalomyelitis, a model of multiple sclerosis. Experimental Biology and Medicine (Maywood, N.J.). PMID 26202376 DOI: 10.1177/1535370215596384 |
0.315 |
|
| 2015 |
McLaughlin PJ, Zagon IS. Duration of Opioid Receptor Blockade Determines Biotherapeutic Response. Biochemical Pharmacology. PMID 26119823 DOI: 10.1016/J.Bcp.2015.06.016 |
0.456 |
|
| 2015 |
Kren NP, Zagon IS, McLaughlin PJ. Mutations in the opioid growth factor receptor in human cancers alter receptor function. International Journal of Molecular Medicine. 36: 289-93. PMID 26005722 DOI: 10.3892/Ijmm.2015.2221 |
0.38 |
|
| 2015 |
McLaughlin PJ, McHugh DP, Magister MJ, Zagon IS. Endogenous opioid inhibition of proliferation of T and B cell subpopulations in response to immunization for experimental autoimmune encephalomyelitis. Bmc Immunology. 16: 24. PMID 25906771 DOI: 10.1186/S12865-015-0093-0 |
0.319 |
|
| 2015 |
Hammer LA, Zagon IS, McLaughlin PJ. Improved clinical behavior of established relapsing-remitting experimental autoimmune encephalomyelitis following treatment with endogenous opioids: implications for the treatment of multiple sclerosis. Brain Research Bulletin. 112: 42-51. PMID 25647234 DOI: 10.1016/J.Brainresbull.2015.01.009 |
0.364 |
|
| 2015 |
Worley B, Zagon I, McLaughlin P. Opioid growth factor receptor (OGFR) expression is downregulated with progression of triple negative breast cancer International Journal of Cancer Therapy and Oncology. 3: 347. DOI: 10.14319/Ijcto.34.7 |
0.396 |
|
| 2014 |
Immonen JA, Zagon IS, McLaughlin PJ. Selective blockade of the OGF-OGFr pathway by naltrexone accelerates fibroblast proliferation and wound healing. Experimental Biology and Medicine (Maywood, N.J.). 239: 1300-9. PMID 25030485 DOI: 10.1177/1535370214543061 |
0.474 |
|
| 2014 |
Immonen JA, Zagon IS, McLaughlin PJ. Topical Naltrexone as Treatment for Type 2 Diabetic Cutaneous Wounds. Advances in Wound Care. 3: 419-427. PMID 24940556 DOI: 10.1089/Wound.2014.0543 |
0.349 |
|
| 2014 |
Zagon IS, McLaughlin PJ. Opioid growth factor and the treatment of human pancreatic cancer: a review. World Journal of Gastroenterology : Wjg. 20: 2218-23. PMID 24605021 DOI: 10.3748/Wjg.V20.I9.2218 |
0.422 |
|
| 2014 |
Zagon IS, Sassani JW, Immonen JA, McLaughlin PJ. Ocular surface abnormalities related to type 2 diabetes are reversed by the opioid antagonist naltrexone. Clinical & Experimental Ophthalmology. 42: 159-68. PMID 23777539 DOI: 10.1111/Ceo.12144 |
0.301 |
|
| 2013 |
Immonen JA, Zagon IS, Lewis GS, McLaughlin PJ. Topical treatment with the opioid antagonist naltrexone accelerates the remodeling phase of full-thickness wound healing in type 1 diabetic rats. Experimental Biology and Medicine (Maywood, N.J.). 238: 1127-35. PMID 23986225 DOI: 10.1177/1535370213502632 |
0.322 |
|
| 2013 |
Hammer LA, Zagon IS, McLaughlin PJ. Treatment of a relapse-remitting model of multiple sclerosis with opioid growth factor. Brain Research Bulletin. 98: 122-31. PMID 23973432 DOI: 10.1016/J.Brainresbull.2013.08.001 |
0.35 |
|
| 2013 |
Zagon IS, Porterfield NK, McLaughlin PJ. Opioid growth factor - opioid growth factor receptor axis inhibits proliferation of triple negative breast cancer. Experimental Biology and Medicine (Maywood, N.J.). 238: 589-99. PMID 23918871 DOI: 10.1177/1535370213489492 |
0.434 |
|
| 2013 |
Zagon IS, Donahue R, McLaughlin PJ. Targeting the opioid growth factor: opioid growth factor receptor axis for treatment of human ovarian cancer. Experimental Biology and Medicine (Maywood, N.J.). 238: 579-87. PMID 23856908 DOI: 10.1177/1535370213488483 |
0.45 |
|
| 2013 |
McLaughlin PJ, Immonen JA, Zagon IS. Topical naltrexone accelerates full-thickness wound closure in type 1 diabetic rats by stimulating angiogenesis. Experimental Biology and Medicine (Maywood, N.J.). 238: 733-43. PMID 23788174 DOI: 10.1177/1535370213492688 |
0.327 |
|
| 2013 |
Rogosnitzky M, Finegold MJ, McLaughlin PJ, Zagon IS. Opioid growth factor (OGF) for hepatoblastoma: a novel non-toxic treatment. Investigational New Drugs. 31: 1066-70. PMID 23275062 DOI: 10.1007/S10637-012-9918-3 |
0.315 |
|
| 2013 |
Campbell AM, Zagon IS, McLaughlin PJ. Astrocyte proliferation is regulated by the OGF-OGFr axis in vitro and in experimental autoimmune encephalomyelitis. Brain Research Bulletin. 90: 43-51. PMID 22985690 DOI: 10.1016/J.Brainresbull.2012.09.001 |
0.376 |
|
| 2013 |
Zagon IS, McLaughlin PJ. Endogenous Opioids and the Treatment of Multiple Sclerosis Journal of Neurology and Neurophysiology. 2014. DOI: 10.4172/2155-9562.S12-011 |
0.349 |
|
| 2012 |
Campbell AM, Zagon IS, McLaughlin PJ. Opioid growth factor arrests the progression of clinical disease and spinal cord pathology in established experimental autoimmune encephalomyelitis. Brain Research. 1472: 138-48. PMID 22820301 DOI: 10.1016/J.Brainres.2012.07.006 |
0.353 |
|
| 2012 |
McLaughlin PJ, Zagon IS. The opioid growth factor-opioid growth factor receptor axis: homeostatic regulator of cell proliferation and its implications for health and disease. Biochemical Pharmacology. 84: 746-55. PMID 22687282 DOI: 10.1016/J.Bcp.2012.05.018 |
0.454 |
|
| 2012 |
Zagon IS, Campbell AM, Sassani JW, McLaughlin PJ. Spontaneous episodic decreased tear secretion in rats is related to opioidergic signaling pathways. Investigative Ophthalmology & Visual Science. 53: 3234-40. PMID 22511629 DOI: 10.1167/Iovs.11-9051 |
0.342 |
|
| 2012 |
McLaughlin PJ, Keiper CL, Verderame MF, Zagon IS. Targeted overexpression of OGFr in epithelium of transgenic mice suppresses cell proliferation and impairs full-thickness wound closure. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 302: R1084-90. PMID 22338080 DOI: 10.1152/Ajpregu.00670.2011 |
0.381 |
|
| 2012 |
Donahue RN, McLaughlin PJ, Zagon IS. Under-expression of the opioid growth factor receptor promotes progression of human ovarian cancer. Experimental Biology and Medicine (Maywood, N.J.). 237: 167-77. PMID 22328595 DOI: 10.1258/Ebm.2011.011321 |
0.408 |
|
| 2012 |
Fanning J, Hossler CA, Kesterson JP, Donahue RN, McLaughlin PJ, Zagon IS. Expression of the opioid growth factor-opioid growth factor receptor axis in human ovarian cancer. Gynecologic Oncology. 124: 319-24. PMID 22037317 DOI: 10.1016/J.Ygyno.2011.10.024 |
0.387 |
|
| 2012 |
McLaughlin PJ, Stucki JK, Zagon IS. Modulation of the opioid growth factor ([Met(5)]-enkephalin)-opioid growth factor receptor axis: novel therapies for squamous cell carcinoma of the head and neck. Head & Neck. 34: 513-9. PMID 21584896 DOI: 10.1002/Hed.21759 |
0.433 |
|
| 2011 |
McLaughlin PJ, Pothering CA, Immonen JA, Zagon IS. Topical treatment with the opioid antagonist naltrexone facilitates closure of full-thickness wounds in diabetic rats. Experimental Biology and Medicine (Maywood, N.J.). 236: 1122-32. PMID 21917593 DOI: 10.1258/Ebm.2011.011163 |
0.37 |
|
| 2011 |
Zagon IS, McLaughlin PJ. Targeting opioid signaling in Crohn's disease: new therapeutic pathways. Expert Review of Gastroenterology & Hepatology. 5: 555-8. PMID 21910569 DOI: 10.1586/Egh.11.62 |
0.383 |
|
| 2011 |
Donahue RN, McLaughlin PJ, Zagon IS. Low-dose naltrexone targets the opioid growth factor-opioid growth factor receptor pathway to inhibit cell proliferation: mechanistic evidence from a tissue culture model. Experimental Biology and Medicine (Maywood, N.J.). 236: 1036-50. PMID 21807817 DOI: 10.1258/Ebm.2011.011121 |
0.473 |
|
| 2011 |
Donahue RN, McLaughlin PJ, Zagon IS. Low-dose naltrexone suppresses ovarian cancer and exhibits enhanced inhibition in combination with cisplatin. Experimental Biology and Medicine (Maywood, N.J.). 236: 883-95. PMID 21685240 DOI: 10.1258/Ebm.2011.011096 |
0.461 |
|
| 2011 |
Donahue RN, McLaughlin PJ, Zagon IS. The opioid growth factor (OGF) and low dose naltrexone (LDN) suppress human ovarian cancer progression in mice. Gynecologic Oncology. 122: 382-8. PMID 21531450 DOI: 10.1016/J.Ygyno.2011.04.009 |
0.478 |
|
| 2011 |
Smith JP, Bingaman SI, Ruggiero F, Mauger DT, Mukherjee A, McGovern CO, Zagon IS. Therapy with the opioid antagonist naltrexone promotes mucosal healing in active Crohn's disease: a randomized placebo-controlled trial. Digestive Diseases and Sciences. 56: 2088-97. PMID 21380937 DOI: 10.1007/S10620-011-1653-7 |
0.414 |
|
| 2011 |
Rahn KA, McLaughlin PJ, Zagon IS. Prevention and diminished expression of experimental autoimmune encephalomyelitis by low dose naltrexone (LDN) or opioid growth factor (OGF) for an extended period: Therapeutic implications for multiple sclerosis. Brain Research. 1381: 243-53. PMID 21256121 DOI: 10.1016/J.Brainres.2011.01.036 |
0.385 |
|
| 2011 |
Zagon IS, Donahue RN, Bonneau RH, McLaughlin PJ. T lymphocyte proliferation is suppressed by the opioid growth factor ([Met(5)]-enkephalin)-opioid growth factor receptor axis: implication for the treatment of autoimmune diseases. Immunobiology. 216: 579-90. PMID 20965606 DOI: 10.1016/J.Imbio.2010.09.014 |
0.417 |
|
| 2011 |
Zagon IS, Donahue RN, Bonneau RH, McLaughlin PJ. B lymphocyte proliferation is suppressed by the opioid growth factor-opioid growth factor receptor axis: Implication for the treatment of autoimmune diseases. Immunobiology. 216: 173-83. PMID 20598772 DOI: 10.1016/j.imbio.2010.06.001 |
0.366 |
|
| 2011 |
Donahue RN, Zagon IS, McLaughlin PJ. The Opioid Growth Factor Inhibits Established Ovarian Cancer in Nude Mice and Can Be Combined with Taxol or Cisplatin to Enhance Growth Inhibition Journal of Cancer Therapy. 2: 110-124. DOI: 10.4236/Jct.2011.22013 |
0.418 |
|
| 2010 |
McLaughlin PJ, Rogosnitzky M, Zagon IS. Inhibition of DNA synthesis in mouse epidermis by topical imiquimod is dependent on opioid receptors. Experimental Biology and Medicine (Maywood, N.J.). 235: 1292-9. PMID 20975079 DOI: 10.1258/Ebm.2010.010203 |
0.441 |
|
| 2010 |
Smith JP, Bingaman SI, Mauger DT, Harvey HH, Demers LM, Zagon IS. Opioid growth factor improves clinical benefit and survival in patients with advanced pancreatic cancer. Open Access Journal of Clinical Trials. 2010: 37-48. PMID 20890374 DOI: 10.2147/Oajct.S8270 |
0.313 |
|
| 2010 |
Cheng F, McLaughlin PJ, Zagon IS. Regulation of cell proliferation by the opioid growth factor receptor is dependent on karyopherin beta and Ran for nucleocytoplasmic trafficking. Experimental Biology and Medicine (Maywood, N.J.). 235: 1093-101. PMID 20705629 DOI: 10.1258/Ebm.2010.010139 |
0.318 |
|
| 2010 |
Cheng F, McLaughlin PJ, Banks WA, Zagon IS. Internalization of the opioid growth factor, [Met5]-enkephalin, is dependent on clathrin-mediated endocytosis for downregulation of cell proliferation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 299: R774-85. PMID 20592180 DOI: 10.1152/Ajpregu.00318.2010 |
0.474 |
|
| 2010 |
Klocek MS, Sassani JW, Donahue RN, McLaughlin PJ, Zagon IS. Regulation of Tenon's capsule fibroblast cell proliferation by the opioid growth factor and the opioid growth factor receptor axis. Investigative Ophthalmology & Visual Science. 51: 5054-61. PMID 20463323 DOI: 10.1167/Iovs.09-4949 |
0.443 |
|
| 2010 |
Zagon IS, Rahn KA, Bonneau RH, Turel AP, McLaughlin PJ. Opioid growth factor suppresses expression of experimental autoimmune encephalomyelitis. Brain Research. 1310: 154-61. PMID 19931226 DOI: 10.1016/J.Brainres.2009.11.026 |
0.425 |
|
| 2010 |
Avella DM, Kimchi ET, Donahue RN, Tagaram HR, McLaughlin PJ, Zagon IS, Staveley-O'Carroll KF. The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R459-66. PMID 19923357 DOI: 10.1152/Ajpregu.00646.2009 |
0.414 |
|
| 2010 |
Zagon IS, Sassani JW, Carroll MA, McLaughlin PJ. Topical application of naltrexone facilitates reepithelialization of the cornea in diabetic rabbits. Brain Research Bulletin. 81: 248-55. PMID 19853024 DOI: 10.1016/J.Brainresbull.2009.10.009 |
0.306 |
|
| 2010 |
McLaughlin PJ, Sassani JW, Klocek MS, Zagon IS. Diabetic keratopathy and treatment by modulation of the opioid growth factor (OGF)-OGF receptor (OGFr) axis with naltrexone: a review. Brain Research Bulletin. 81: 236-47. PMID 19683562 DOI: 10.1016/J.Brainresbull.2009.08.008 |
0.401 |
|
| 2010 |
McLaughlin PJ, Stucki J, Zagon IS. Abstract 697: Inhibition of Cancer Progression by Upregulation of the Opioid Growth Factor (OGF) - OGF Receptor (OGFr) Axis Using Imquimod or Low Dose Naltrexone Cancer Research. 70: 697-697. DOI: 10.1158/1538-7445.Am10-697 |
0.407 |
|
| 2010 |
Donahue RN, McLaughlin PJ, Zagon IS. Abstract 4153: Short term opioid receptor blockade inhibits cancer cell proliferation independent of immune function by upregulation of the OGF-OGFr axis: A tissue culture model of low dose naltrexone (LDN) Cancer Research. 70: 4153-4153. DOI: 10.1158/1538-7445.Am10-4153 |
0.452 |
|
| 2009 |
Zagon IS, Rahn KA, Turel AP, McLaughlin PJ. Endogenous opioids regulate expression of experimental autoimmune encephalomyelitis: a new paradigm for the treatment of multiple sclerosis. Experimental Biology and Medicine (Maywood, N.J.). 234: 1383-92. PMID 19855075 DOI: 10.3181/0906-Rm-189 |
0.399 |
|
| 2009 |
McLaughlin PJ, Zagon IS, Park SS, Conway A, Donahue RN, Goldenberg D. Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis. Bmc Cancer. 9: 369. PMID 19835629 DOI: 10.1186/1471-2407-9-369 |
0.432 |
|
| 2009 |
Zagon IS, Donahue RN, McLaughlin PJ. Opioid growth factor-opioid growth factor receptor axis is a physiological determinant of cell proliferation in diverse human cancers. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1154-61. PMID 19675283 DOI: 10.1152/Ajpregu.00414.2009 |
0.436 |
|
| 2009 |
Cheng F, McLaughlin PJ, Banks WA, Zagon IS. Passive diffusion of naltrexone into human and animal cells and upregulation of cell proliferation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R844-52. PMID 19605761 DOI: 10.1152/Ajpregu.00311.2009 |
0.396 |
|
| 2009 |
Klocek MS, Sassani JW, McLaughlin PJ, Zagon IS. Naltrexone and insulin are independently effective but not additive in accelerating corneal epithelial healing in type I diabetic rats. Experimental Eye Research. 89: 686-92. PMID 19576213 DOI: 10.1016/J.Exer.2009.06.010 |
0.306 |
|
| 2009 |
Donahue RN, McLaughlin PJ, Zagon IS. Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R1716-25. PMID 19297547 DOI: 10.1152/Ajpregu.00075.2009 |
0.437 |
|
| 2009 |
Cheng F, McLaughlin PJ, Verderame MF, Zagon IS. Dependence on nuclear localization signals of the opioid growth factor receptor in the regulation of cell proliferation. Experimental Biology and Medicine (Maywood, N.J.). 234: 532-41. PMID 19244545 DOI: 10.3181/0901-Rm-16 |
0.388 |
|
| 2009 |
Cheng F, McLaughlin PJ, Verderame MF, Zagon IS. The OGF-OGFr axis utilizes the p16INK4a and p21WAF1/CIP1 pathways to restrict normal cell proliferation. Molecular Biology of the Cell. 20: 319-27. PMID 18923142 DOI: 10.1091/Mbc.E08-07-0681 |
0.356 |
|
| 2009 |
Avella Patino D, Tagaram H, Kimchi E, McLaughlin P, Zagon I, Staveley-O'Carroll K. QS297. Opioid Growth Factor Inhibits Cell Replication and DNA Synthesis of Hepatocellular Cancer In Vitro Through a Receptor Mediated Mechanism Journal of Surgical Research. 151: 296. DOI: 10.1016/J.Jss.2008.11.603 |
0.424 |
|
| 2008 |
Goldenberg D, Zagon IS, Fedok F, Crist HS, McLaughlin PJ. Expression of opioid growth factor (OGF)-OGF receptor (OGFr) axis in human nonmedullary thyroid cancer. Thyroid : Official Journal of the American Thyroid Association. 18: 1165-70. PMID 19014324 DOI: 10.1089/Thy.2008.0112 |
0.359 |
|
| 2008 |
McLaughlin PJ, Kreiner S, Morgan CR, Zagon IS. Prevention and delay in progression of human squamous cell carcinoma of the head and neck in nude mice by stable overexpression of the opioid growth factor receptor. International Journal of Oncology. 33: 751-7. PMID 18813788 DOI: 10.3892/Ijo_00000061 |
0.368 |
|
| 2008 |
Zagon IS, Kreiner S, Heslop JJ, Conway AB, Morgan CR, McLaughlin PJ. Prevention and delay in progression of human pancreatic cancer by stable overexpression of the opioid growth factor receptor. International Journal of Oncology. 33: 317-23. PMID 18636152 DOI: 10.3892/Ijo_00000011 |
0.378 |
|
| 2008 |
Zagon IS, Donahue RN, Rogosnitzky M, McLaughlin PJ. Imiquimod upregulates the opioid growth factor receptor to inhibit cell proliferation independent of immune function. Experimental Biology and Medicine (Maywood, N.J.). 233: 968-79. PMID 18480416 DOI: 10.3181/0802-Rm-58 |
0.414 |
|
| 2008 |
Cheng F, McLaughlin PJ, Verderame MF, Zagon IS. The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer. Molecular Cancer. 7: 5. PMID 18190706 DOI: 10.1186/1476-4598-7-5 |
0.354 |
|
| 2008 |
Smith JP, Bingaman SI, Mauger DT, Harvey HA, Demers LM, Zagon IS. OPIOID GROWTH FACTOR (OGF) IMPROVES SURVIVAL IN PATIENTS WITH ADVANCED PANCREATIC CANCER Pancreas. 37: 496. DOI: 10.1097/01.Mpa.0000335392.30143.9E |
0.368 |
|
| 2008 |
Goldenberg D, Zagon I, McLaughlin PJ. QS106. The Opioid Growth Factor Axis in Human Thyroid Cancer Journal of Surgical Research. 144: 310. DOI: 10.1016/J.Jss.2007.12.346 |
0.391 |
|
| 2007 |
Cheng F, Zagon IS, Verderame MF, McLaughlin PJ. The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancer. Cancer Research. 67: 10511-8. PMID 17974995 DOI: 10.1158/0008-5472.Can-07-1922 |
0.379 |
|
| 2007 |
Zagon IS, Rahn KA, McLaughlin PJ. Opioids and migration, chemotaxis, invasion, and adhesion of human cancer cells. Neuropeptides. 41: 441-52. PMID 17910895 DOI: 10.1016/J.Npep.2007.08.002 |
0.447 |
|
| 2007 |
Klocek MS, Sassani JW, McLaughlin PJ, Zagon IS. Topically applied naltrexone restores corneal reepithelialization in diabetic rats. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 23: 89-102. PMID 17444796 DOI: 10.1089/Jop.2006.0111 |
0.326 |
|
| 2007 |
Zagon IS, Verderame MF, Hankins J, McLaughlin PJ. Overexpression of the opioid growth factor receptor potentiates growth inhibition in human pancreatic cancer cells. International Journal of Oncology. 30: 775-83. PMID 17332915 DOI: 10.3892/Ijo.30.4.775 |
0.431 |
|
| 2007 |
Zagon IS, Sassani JW, Myers RL, McLaughlin PJ. Naltrexone accelerates healing without compromise of adhesion complexes in normal and diabetic corneal epithelium. Brain Research Bulletin. 72: 18-24. PMID 17303503 DOI: 10.1016/J.Brainresbull.2006.12.007 |
0.303 |
|
| 2007 |
McLaughlin PJ, Verderame MF, Hankins JL, Zagon IS. Overexpression of the opioid growth factor receptor downregulates cell proliferation of human squamous carcinoma cells of the head and neck. International Journal of Molecular Medicine. 19: 421-8. PMID 17273790 DOI: 10.3892/Ijmm.19.3.421 |
0.415 |
|
| 2007 |
Smith JP, Stock H, Bingaman S, Mauger D, Rogosnitzky M, Zagon IS. Low-dose naltrexone therapy improves active Crohn's disease. The American Journal of Gastroenterology. 102: 820-8. PMID 17222320 DOI: 10.1111/J.1572-0241.2007.01045.X |
0.376 |
|
| 2006 |
Zagon IS, Sassani JW, Malefyt KJ, McLaughlin PJ. Regulation of corneal repair by particle-mediated gene transfer of opioid growth factor receptor complementary DNA. Archives of Ophthalmology (Chicago, Ill. : 1960). 124: 1620-4. PMID 17102011 DOI: 10.1001/Archopht.124.11.1620 |
0.393 |
|
| 2006 |
Zagon IS, Klocek MS, Sassani JW, Mauger DT, McLaughlin PJ. Corneal safety of topically applied naltrexone. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 22: 377-87. PMID 17076633 DOI: 10.1089/Jop.2006.22.377 |
0.329 |
|
| 2006 |
Zagon IS, Sassani JW, McLaughlin PJ. Adaptation of homeostatic ocular surface epithelium to chronic treatment with the opioid antagonist naltrexone. Cornea. 25: 821-9. PMID 17068460 DOI: 10.1097/01.Ico.0000224646.66472.Aa |
0.386 |
|
| 2006 |
Zagon IS, McLaughlin PJ. Opioid growth factor receptor is unaltered with the progression of human pancreatic and colon cancers. International Journal of Oncology. 29: 489-94. PMID 16820893 DOI: 10.3892/Ijo.29.2.489 |
0.432 |
|
| 2006 |
McLaughlin PJ, Zagon IS. Progression of squamous cell carcinoma of the head and neck is associated with down-regulation of the opioid growth factor receptor. International Journal of Oncology. 28: 1577-83. PMID 16685459 DOI: 10.3892/Ijo.28.6.1577 |
0.407 |
|
| 2006 |
Hurst WJ, McLaughlin PJ, Zagon IS, Rogosnitzky M. Stability of opioid growth factor ([Met5]-enkephalin) in solution using HPLC and photodiode array detection Journal of Liquid Chromatography and Related Technologies. 29: 151-157. DOI: 10.1080/10826070500416395 |
0.346 |
|
| 2005 |
Zagon IS, McLaughlin PJ. Opioids and differentiation in human cancer cells. Neuropeptides. 39: 495-505. PMID 16169076 DOI: 10.1016/J.Npep.2005.07.001 |
0.455 |
|
| 2005 |
Zagon IS, Sassani JW, Verderame MF, McLaughlin PJ. Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell proliferation of the corneal epithelium. Cornea. 24: 614-9. PMID 15968171 DOI: 10.1097/01.Ico.0000153561.89902.57 |
0.415 |
|
| 2005 |
Zagon IS, Jaglowski JR, Verderame MF, Smith JP, Leure-Dupree AE, McLaughlin PJ. Combination chemotherapy with gemcitabine and biotherapy with opioid growth factor (OGF) enhances the growth inhibition of pancreatic adenocarcinoma. Cancer Chemotherapy and Pharmacology. 56: 510-20. PMID 15947928 DOI: 10.1007/S00280-005-1028-X |
0.423 |
|
| 2005 |
Jaglowski JR, Zagon IS, Stack BC, Verderame MF, Leure-duPree AE, Manning JD, McLaughlin PJ. Opioid growth factor enhances tumor growth inhibition and increases the survival of paclitaxel-treated mice with squamous cell carcinoma of the head and neck. Cancer Chemotherapy and Pharmacology. 56: 97-104. PMID 15791460 DOI: 10.1007/S00280-004-0929-4 |
0.391 |
|
| 2005 |
McLaughlin PJ, Jaglowski JR, Verderame MF, Stack BC, Leure-Dupree AE, Zagon IS. Enhanced growth inhibition of squamous cell carcinoma of the head and neck by combination therapy of paclitaxel and opioid growth factor. International Journal of Oncology. 26: 809-16. PMID 15703840 DOI: 10.3892/Ijo.26.3.809 |
0.409 |
|
| 2005 |
Zagon IS, Ruth TB, McLaughlin PJ. Nucleocytoplasmic distribution of opioid growth factor and its receptor in tongue epithelium. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 282: 24-37. PMID 15584033 DOI: 10.1002/Ar.A.20161 |
0.401 |
|
| 2004 |
Smith JP, Stanley WB, Verderame MF, Zagon IS. The functional significance of the cholecystokinin-C (CCK-C) receptor in human pancreatic cancer. Pancreas. 29: 271-7. PMID 15502642 DOI: 10.1097/00006676-200411000-00005 |
0.327 |
|
| 2004 |
Zagon IS, McLaughlin PJ. Opioid growth factor (OGF) inhibits anchorage-independent growth in human cancer cells. International Journal of Oncology. 24: 1443-8. PMID 15138586 DOI: 10.3892/Ijo.24.6.1443 |
0.465 |
|
| 2004 |
Zagon IS, McLaughlin PJ. Gene expression of OGFr in the developing and adult rat brain and cerebellum. Brain Research Bulletin. 63: 57-63. PMID 15121239 DOI: 10.1016/J.Brainresbull.2003.12.002 |
0.4 |
|
| 2004 |
Smith JP, Conter RL, Bingaman SI, Harvey HA, Mauger DT, Ahmad M, Demers LM, Stanley WB, McLaughlin PJ, Zagon IS. Treatment of advanced pancreatic cancer with opioid growth factor: phase I. Anti-Cancer Drugs. 15: 203-9. PMID 15014352 DOI: 10.1097/00001813-200403000-00003 |
0.334 |
|
| 2004 |
Smith JP, Verderame MF, Ballard EN, Zagon IS. Functional significance of gastrin gene expression in human cancer cells. Regulatory Peptides. 117: 167-73. PMID 14749036 DOI: 10.1016/J.Regpep.2003.10.013 |
0.376 |
|
| 2004 |
McLaughlin PJ, Stack BC, Braine KM, Ruda JD, Zagon IS. Opioid growth factor inhibition of a human squamous cell carcinoma of the head and neck in nude mice: dependency on the route of administration. International Journal of Oncology. 24: 227-32. PMID 14654962 DOI: 10.3892/Ijo.24.1.227 |
0.422 |
|
| 2003 |
Zagon IS, Verderame MF, McLaughlin PJ. The expression and function of the OGF-OGFr axis - a tonically active negative regulator of growth - in COS cells. Neuropeptides. 37: 290-7. PMID 14607106 DOI: 10.1016/J.Npep.2003.07.001 |
0.462 |
|
| 2003 |
McLaughlin PJ, Levin RJ, Zagon IS. Opioid growth factor (OGF) inhibits the progression of human squamous cell carcinoma of the head and neck transplanted into nude mice. Cancer Letters. 199: 209-17. PMID 12969794 DOI: 10.1016/S0304-3835(03)00341-0 |
0.453 |
|
| 2003 |
Sassani JW, Zagon IS, McLaughlin PJ. Opioid growth factor modulation of corneal epithelium: uppers and downers. Current Eye Research. 26: 249-62. PMID 12854052 DOI: 10.1076/Ceyr.26.4.249.15427 |
0.433 |
|
| 2003 |
Zagon IS, McLaughlin PJ. Opioids and the apoptotic pathway in human cancer cells. Neuropeptides. 37: 79-88. PMID 12747939 DOI: 10.1016/S0143-4179(03)00007-6 |
0.457 |
|
| 2003 |
McLaughlin PJ, Stack BC, Levin RJ, Fedok F, Zagon IS. Defects in the opioid growth factor receptor in human squamous cell carcinoma of the head and neck. Cancer. 97: 1701-10. PMID 12655527 DOI: 10.1002/Cncr.11237 |
0.389 |
|
| 2003 |
Zagon IS, Ruth TB, Leure-duPree AE, Sassani JW, McLaughlin PJ. Immunoelectron microscopic localization of the opioid growth factor receptor (OGFr) and OGF in the cornea. Brain Research. 967: 37-47. PMID 12650964 DOI: 10.1016/S0006-8993(02)04172-0 |
0.383 |
|
| 2003 |
Zagon IS, Essis FM, Verderame MF, Healy DA, Atnip RG, McLaughlin PJ. Opioid growth factor inhibits intimal hyperplasia in balloon-injured rat carotid artery. Journal of Vascular Surgery. 37: 636-43. PMID 12618704 DOI: 10.1067/Mva.2003.165 |
0.45 |
|
| 2002 |
Smith JP, Verderame MF, McLaughlin P, Martenis M, Ballard E, Zagon IS. Characterization of the CCK-C (cancer) receptor in human pancreatic cancer. International Journal of Molecular Medicine. 10: 689-94. PMID 12429993 DOI: 10.3892/Ijmm.10.6.689 |
0.354 |
|
| 2002 |
Zagon IS, Jenkins JB, Sassani JW, Wylie JD, Ruth TB, Fry JL, Lang CM, McLaughlin PJ. Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in diabetic rat. Diabetes. 51: 3055-62. PMID 12351447 DOI: 10.2337/Diabetes.51.10.3055 |
0.352 |
|
| 2002 |
Zagon IS, Verderame MF, McLaughlin PJ. The biology of the opioid growth factor receptor (OGFr). Brain Research. Brain Research Reviews. 38: 351-76. PMID 11890982 DOI: 10.1016/S0165-0173(01)00160-6 |
0.448 |
|
| 2002 |
McLaughlin PJ, Wylie JD, Bloom G, Griffith JW, Zagon IS. Chronic exposure to the opioid growth factor, [Met5]-enkephalin, during pregnancy: maternal and preweaning effects. Pharmacology, Biochemistry, and Behavior. 71: 171-81. PMID 11812520 DOI: 10.1016/S0091-3057(01)00649-9 |
0.392 |
|
| 2001 |
Zagon IS, Wylie JD, Hurst WJ, McLaughlin PJ. Transplacental transfer of the opioid growth factor, [Met(5)]-enkephalin, in rats. Brain Research Bulletin. 55: 341-6. PMID 11489341 DOI: 10.1016/S0361-9230(01)00518-4 |
0.396 |
|
| 2000 |
Zagon IS, Verderame MF, Zimmer WE, McLaughlin PJ. Molecular characterization and distribution of the opioid growth factor receptor (OGFr) in mouse. Brain Research. Molecular Brain Research. 84: 106-14. PMID 11113537 DOI: 10.1016/S0169-328X(00)00232-1 |
0.412 |
|
| 2000 |
Zagon IS, Sassani JW, Ruth TB, McLaughlin PJ. Cellular dynamics of corneal wound re-epithelialization in the rat. III. Mitotic activity. Brain Research. 882: 169-79. PMID 11056196 DOI: 10.1016/S0006-8993(00)02864-X |
0.303 |
|
| 2000 |
Smith JP, Conter RL, Demers TM, McLaughlin PJ, Zagon IS. Elevated levels of opioid growth factor in the plasma of patients with pancreatic cancer. Pancreas. 21: 158-64. PMID 10975710 DOI: 10.1097/00006676-200008000-00009 |
0.319 |
|
| 2000 |
Wilson RP, McLaughlin PJ, Lang CM, Zagon IS. The opioid growth factor, [Met5]-enkephalin, inhibits DNA synthesis during recornification of mouse tail skin Cell Proliferation. 33: 63-73. PMID 10845251 DOI: 10.1046/J.1365-2184.2000.00161.X |
0.461 |
|
| 2000 |
Zalys R, Zagon IS, Bonneau RH, Lang CM, McLaughlin PJ. In vivo effects of chronic treatment with [Met5]-enkephalin on hematological values and natural killer cell activity in athymic mice Life Sciences. 66: 829-834. PMID 10698357 DOI: 10.1016/S0024-3205(99)00655-4 |
0.449 |
|
| 2000 |
Zagon IS, Verderame MF, Allen SS, McLaughlin PJ. Cloning, sequencing, chromosomal location, and function of cDNAs encoding an opioid growth factor receptor (OGFr) in humans Brain Research. 856: 75-83. PMID 10677613 DOI: 10.1016/S0006-8993(99)02330-6 |
0.416 |
|
| 2000 |
McLaughlin PJ, Levin RJ, Zagon IS. The opioid growth factor receptor in human head and neck squamous cell carcinoma International Journal of Molecular Medicine. 5: 191-196. PMID 10639600 DOI: 10.3892/Ijmm.5.2.191 |
0.409 |
|
| 2000 |
Zagon IS, Smith JP, Conter R, McLaughlin PJ. Identification and characterization of opioid growth factor receptor in human pancreatic adenocarcinoma International Journal of Molecular Medicine. 5: 77-84. PMID 10601579 DOI: 10.1016/S0016-5085(00)80450-3 |
0.394 |
|
| 2000 |
Smith JP, Conter R, Demers LM, McLaughlin PI, Zagon IS. Elevated plasma opioid growth factor levels in human pancreatic cancer Gastroenterology. 118: A647. DOI: 10.1016/S0016-5085(00)84727-7 |
0.377 |
|
| 2000 |
Martenis M, Smith JP, Ballard E, Verderame MF, Zagon IS. Identification of the CCK-C receptor in humanpancreatic cancer cells and tissues Gastroenterology. 118: A645. DOI: 10.1016/S0016-5085(00)84720-4 |
0.318 |
|
| 2000 |
Zagon IS, Smith JP, Roesener CD, Verderame MF, McLaughlin PJ. Cell cycle alterations and the inhibition of humanpancreatic cell replication by opioid growth factor Gastroenterology. 118: A563. DOI: 10.1016/S0016-5085(00)84386-3 |
0.424 |
|
| 2000 |
Zagon IS, Verderame MF, Allen SS, McLaughlin PJ. Cloning, sequencing, chromosomal wcation, and function of a cdna encoding the opioid growth factor receptor (OGFR) in humans and a modulator of ogf activity in the growth of pancreatic and colorectal cancer Gastroenterology. 118: A417. DOI: 10.1016/S0016-5085(00)83780-4 |
0.38 |
|
| 2000 |
Ahmad M, Smith JP, Conter R, Harvey H, McLaughlin P, Bingaman S, Mauger DT, Zagon IS. Treatment of advanced pancreatic cancer patients with opioid growth factor The American Journal of Gastroenterology. 95: 2471-2472. DOI: 10.1016/S0002-9270(00)01358-7 |
0.407 |
|
| 1999 |
Zagon IS, Verderame MF, Allen SS, McLaughlin PJ. Cloning, sequencing, expression and function of a cDNA encoding a receptor for the opioid growth factor, [Met5]enkephalin Brain Research. 849: 147-154. PMID 10592296 DOI: 10.1016/S0006-8993(99)02046-6 |
0.428 |
|
| 1999 |
Bisignani GJ, McLaughlin PJ, Ordille SD, Beltz MS, Jarowenko MV, Zagon IS. Human renal cell cancer proliferation in tissue culture is tonically inhibited by opioid growth factor Journal of Urology. 162: 2186-2191. PMID 10569617 DOI: 10.1016/S0022-5347(05)68157-8 |
0.445 |
|
| 1999 |
Zagon IS, Wu Y, McLaughlin PJ. Opioid growth factor and organ development in rat and human embryos Brain Research. 839: 313-322. PMID 10519055 DOI: 10.1016/S0006-8993(99)01753-9 |
0.487 |
|
| 1999 |
Zagon IS, Sassani JW, McLaughlin PJ. Cellular dynamics of corneal wound re-epithelialization in the rat. II. DNA synthesis of the ocular surface epithelium following wounding Brain Research. 839: 243-252. PMID 10519047 DOI: 10.1016/S0006-8993(99)01722-9 |
0.304 |
|
| 1999 |
McLaughlin PJ, Levin RJ, Zagon IS. Regulation of human head and neck squamous cell carcinoma growth in tissue culture by Opioid Growth Factor International Journal of Oncology. 14: 991-998. PMID 10200353 DOI: 10.3892/Ijo.14.5.991 |
0.464 |
|
| 1999 |
Zagon IS, Sassani JW, McLaughlin PJ. Cellular dynamics of corneal wound re-epithelialization in the rat I. Fate of ocular surface epithelial cells synthesizing DNA prior to wounding Brain Research. 822: 149-163. PMID 10082893 DOI: 10.1016/S0006-8993(99)01106-3 |
0.311 |
|
| 1999 |
Zagon IS, Smith JP, McLaughlin PJ. Human pancreatic cancer cell proliferation in tissue culture is tonically inhibited by opioid growth factor International Journal of Oncology. 14: 577-584. PMID 10024694 DOI: 10.3892/Ijo.14.3.577 |
0.462 |
|
| 1998 |
Smith JP, Verderame MF, Zagon IS. Antisense oligonucleotides to gastrin inhibit growth of human pancreatic cancer Cancer Letters. 135: 107-112. PMID 10077228 DOI: 10.1016/S0304-3835(98)00279-1 |
0.337 |
|
| 1998 |
Smith JP, Hamory MW, Verderame MF, Zagon IS. Quantitative analysis of gastrin mRNA and peptide in normal and cancerous human pancreas International Journal of Molecular Medicine. 2: 309-315. PMID 9855703 DOI: 10.3892/Ijmm.2.3.309 |
0.327 |
|
| 1998 |
Zagon IS, Sassani JW, McLaughlin PJ. Re-epithelialization of the rabbit cornea is regulated by opioid growth factor Brain Research. 803: 61-68. PMID 9729280 DOI: 10.1016/S0006-8993(98)00610-6 |
0.452 |
|
| 1998 |
Zagon IS, Sassani JW, McLaughlin PJ. Re-epithelialization of the rat cornea is accelerated by blockade of opioid receptors Brain Research. 798: 254-260. PMID 9666142 DOI: 10.1016/S0006-8993(98)00427-2 |
0.453 |
|
| 1998 |
Zagon IS, Sassani JW, Wu Y, McLaughlin PJ. The autocrine derivation of the opioid growth factor, [Met5]- enkephalin, in ocular surface epithelium Brain Research. 792: 72-78. PMID 9593829 DOI: 10.1016/S0006-8993(98)00123-1 |
0.446 |
|
| 1998 |
Wu Y, Mclaughlin PJ, Zagon IS. Ontogeny of the opioid growth factor, [Met5]-enkephalin, preproenkephalin gene expression, and the ζ opioid receptor in the developing and adult aorta of rat Developmental Dynamics. 211: 327-337. PMID 9566952 DOI: 10.1002/(Sici)1097-0177(199804)211:4<327::Aid-Aja4>3.0.Co;2-J |
0.459 |
|
| 1998 |
Zagon IS, Hurst WJ, McLaughlin PJ. Naltrexone is not detected in preweaning rats following transplacental exposure: implications for growth modulation. Life Sciences. 62: 221-8. PMID 9488100 DOI: 10.1016/S0024-3205(97)01090-4 |
0.412 |
|
| 1998 |
Smith JP, Shih AH, Wotring MG, McLaughlin PJ, Zagon IS. Characterization of CCK-B/gastrin-like receptors in human gastric carcinoma International Journal of Oncology. 12: 411-419. PMID 9458369 DOI: 10.3892/Ijo.12.2.411 |
0.332 |
|
| 1998 |
Zagon IS, Tobias SW, Hytrek SD, McLaughlin PJ. Opioid receptor blockade throughout prenatal life confers long-term insensitivity to morphine and alters μ opioid receptors Pharmacology Biochemistry and Behavior. 59: 201-207. PMID 9443556 DOI: 10.1016/S0091-3057(97)00419-X |
0.461 |
|
| 1998 |
Bartek JP, Healy DA, Smilanich RP, Essis FM, McLaughlin PJ, Zagon IS. Opioid Growth Factor Decreases Neointima Formation in the Rat Carotid Artery Journal of Vascular and Interventional Radiology. 9: 711. DOI: 10.1016/S1051-0443(98)70380-X |
0.382 |
|
| 1997 |
Zagon IS, Tobias SW, McLaughlin PJ. Endogenous opioids and prenatal determinants of neuroplasticity Advances in Experimental Medicine and Biology. 429: 289-303. PMID 9413582 DOI: 10.1007/978-1-4757-9551-6_21 |
0.465 |
|
| 1997 |
McLaughlin PJ, Tobias SW, Lang CM, Zagon IS. Opioid receptor blockade during prenatal life modifies postnatal behavioral development Pharmacology Biochemistry and Behavior. 58: 1075-1082. PMID 9408216 DOI: 10.1016/S0091-3057(97)00307-9 |
0.418 |
|
| 1997 |
Zagon IS, Hurst WJ, McLaughlin PJ. Transplacental transfer of naltrexone in rats. Life Sciences. 61: 1261-7. PMID 9324068 DOI: 10.1016/S0024-3205(97)00671-1 |
0.384 |
|
| 1997 |
Zagon IS, Sassani JW, Kane ER, McLaughlin PJ. Homeostasis of ocular surface epithelium in the rat is regulated by opioid growth factor. Brain Research. 759: 92-102. PMID 9219867 DOI: 10.1016/S0006-8993(97)00238-2 |
0.454 |
|
| 1997 |
Levin RJ, Wu Y, McLaughlin PJ, Zagon IS. Expression of the opioid growth factor, [Met5]-enkephalin, and the zeta opioid receptor in head and neck squamous cell carcinoma Laryngoscope. 107: 335-339. PMID 9121309 DOI: 10.1097/00005537-199703000-00011 |
0.433 |
|
| 1997 |
Zagon IS, Hytrek SD, Smith JP, McLaughlin PJ. Opioid growth factor (OGF) inhibits human pancreatic cancer transplanted into nude mice Cancer Letters. 112: 167-175. PMID 9066724 DOI: 10.1016/S0304-3835(96)04566-1 |
0.43 |
|
| 1997 |
Zagon IS, Yan WU. Opioid growth factor is present in human and mouse gastrointestinal tract and inhibits DNA synthesis American Journal of Physiology - Heart and Circulatory Physiology. 41: R1094-R1104. DOI: 10.1152/Ajpregu.1997.272.4.R1094 |
0.439 |
|
| 1997 |
Levin RJ, Wu Y, McLaughlin PJ, Zagon IS. Presence and distribution of opioid growth factor, [Met5]-enkephalin and ζ-opioid receptor in head and neck squamous cell carcinoma Faseb Journal. 11: A429. |
0.317 |
|
| 1996 |
Isayama T, McLaughlin PJ, Zagon IS. Ontogeny of preproenkephalin mRNA expression in the rat retina. Visual Neuroscience. 13: 695-704. PMID 8870226 DOI: 10.1017/S0952523800008580 |
0.384 |
|
| 1996 |
Smith JP, Stock EA, Wotring MG, Mclaughlin PJ, Zagon IS. Characterization of the CCK-B/gastrin-like receptor in human colon cancer American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 271: R797-R805. PMID 8853405 DOI: 10.1152/Ajpregu.1996.271.3.R797 |
0.346 |
|
| 1996 |
Zagon IS, Hytrek SD, Lang CM, Smith JP, Mcgarrity TJ, Wu Y, Mclaughlin PJ. Opioid growth factor ([Met5]enkephalin) prevents the incidence and retards the growth of human colon cancer American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 271: R780-R786. PMID 8853403 DOI: 10.1152/Ajpregu.1996.271.3.R780 |
0.449 |
|
| 1996 |
Zagon IS, Hytrek SD, McLaughlin PJ. Opioid growth factor tonically inhibits human colon cancer cell proliferation in tissue culture American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 271: R511-R518. PMID 8853370 DOI: 10.1152/Ajpregu.1996.271.3.R511 |
0.473 |
|
| 1996 |
Zagon IS, Wu Y, McLaughlin PJ. Opioid growth factor-dependent DNA synthesis in the neonatal rat aorta American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 270: R22-R32. PMID 8769781 DOI: 10.1152/Ajpregu.1996.270.1.R22 |
0.469 |
|
| 1996 |
Zagon IS, Wu Y, McLaughlin PJ. The opioid growth factor, [Met5]-enkephalin, and the ζ (zeta) opioid receptor are present in human and mouse skin and tonically act to inhibit DNA synthesis in the epidermis Journal of Investigative Dermatology. 106: 490-497. PMID 8648182 DOI: 10.1111/1523-1747.Ep12343712 |
0.468 |
|
| 1996 |
Hytrek SD, McLaughlin PJ, Lang CM, Zagon IS. Inhibition of human colon cancer by intermittent opioid receptor blockade with naltrexone Cancer Letters. 101: 159-164. PMID 8620464 DOI: 10.1016/0304-3835(96)04119-5 |
0.444 |
|
| 1996 |
McLaughlin PJ, Zagon IS. Gastrin regulates growth of human pancreatic cancer in a tonic and autocrine fashion American Journal of Physiology. 270: R1078-R1084. DOI: 10.1152/Ajpregu.1996.270.5.R1078 |
0.322 |
|
| 1996 |
Wu Y, McLaughlin PJ, Zagon IS. Opioid growth factor and the zeta (f) opioid receptor are present and function in mammalian esophagus Faseb Journal. 10: A771. |
0.315 |
|
| 1995 |
Zagon IS, McLaughlin PJ. Gene-peptide relationships in the developing rat brain: the response of preproenkephalin rnRNA and [Met5]-enkephalin to acute opioid antagonist (naltrexone) exposure Molecular Brain Research. 33: 111-120. PMID 8774952 DOI: 10.1016/0169-328X(95)00119-D |
0.452 |
|
| 1995 |
Smith JP, Fantaskey AP, Liu G, Zagon IS. Identification of gastrin as a growth peptide in human pancreatic cancer American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 268: R135-R141. PMID 7840313 DOI: 10.1152/Ajpregu.1995.268.1.R135 |
0.386 |
|
| 1995 |
Zagon IS, Sassani JW, McLaughlin PJ. Opioid growth factor modulates corneal epithelial outgrowth in tissue culture American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 268: R942-R950. PMID 7733405 DOI: 10.1152/Ajpregu.1995.268.4.R942 |
0.488 |
|
| 1995 |
Zagon IS, Sassani JW, Allison G, McLaughlin PJ. Conserved expression of the opioid growth factor, [Met5]enkephalin, and the zeta (ζ) opioid receptor in vertebrate cornea Brain Research. 671: 105-111. PMID 7728521 DOI: 10.1016/0006-8993(94)01314-8 |
0.477 |
|
| 1994 |
Smith JP, Liu G, Soundararajan V, McLaughlin PJ, Zagon IS. Identification and characterization of CCK-B/gastrin receptors in human pancreatic cancer cell lines. The American Journal of Physiology. 266: R277-83. PMID 8304551 DOI: 10.1152/Ajpregu.1994.266.1.R277 |
0.346 |
|
| 1994 |
Zagon IS, Isayama T, McLaughlin PJ. Preproenkephalin mRNA expression in the developing and adult rat brain. Brain Research. Molecular Brain Research. 21: 85-98. PMID 8164525 DOI: 10.1016/0169-328X(94)90381-6 |
0.412 |
|
| 1994 |
Zagon IS, Yan W, McLaughlin PJ. Opioid antagonist modulation of DNA synthesis in mouse tongue epithelium is circadian dependent Pharmacology, Biochemistry and Behavior. 48: 709-714. PMID 7938126 DOI: 10.1016/0091-3057(94)90337-9 |
0.457 |
|
| 1994 |
Zagon IS, Wu Yan, McLaughlin PJ. Opioid growth factor inhibits DNA synthesis in mouse tongue epithelium in a circadian rhythm-dependent manner Am.J.Physiol.. 267: R645-R652. DOI: 10.1152/Ajpregu.1994.267.3.R645 |
0.441 |
|
| 1993 |
Zagon IS, Goodman SR, McLaughlin PJ. Zeta (ζ), the opioid growth factor receptor: identification and characterization of binding subunits Brain Research. 605: 50-56. PMID 8385541 DOI: 10.1016/0006-8993(93)91355-V |
0.421 |
|
| 1993 |
Smith JP, Rickabaugh CA, McLaughlin PJ, Zagon IS. Cholecystokinin receptors and PANC-1 human pancreatic cancer cells American Journal of Physiology - Gastrointestinal and Liver Physiology. 265: G149-G155. PMID 8338163 DOI: 10.1152/Ajpgi.1993.265.1.G149 |
0.361 |
|
| 1993 |
Zagon IS, McLaughlin PJ. Production and characterization of polyclonal and monoclonal antibodies to the zeta (ξ) opioid receptor Brain Research. 630: 295-302. PMID 8118696 DOI: 10.1016/0006-8993(93)90669-E |
0.363 |
|
| 1992 |
Wilson RP, Zagon IS, Larach DR, Lang CM. Antinociceptive properties of tiletamine-zolazepam improved by addition of xylazine or butorphanol Pharmacology, Biochemistry and Behavior. 43: 1129-1133. PMID 1475295 DOI: 10.1016/0091-3057(92)90492-X |
0.352 |
|
| 1992 |
Zagon IS, Gibo DM, McLaughlin PJ. Ontogeny of zeta (ζ), the opioid growth factor receptor, in the rat brain Brain Research. 596: 149-156. PMID 1334774 DOI: 10.1016/0006-8993(92)91542-M |
0.424 |
|
| 1992 |
Zagon IS, McLaughlin PJ. An opioid growth factor regulates the replication of microorganisms Life Sciences. 50: 1179-1187. PMID 1313136 DOI: 10.1016/0024-3205(92)90461-W |
0.466 |
|
| 1991 |
Zagon IS, McLaughlin PJ. Identification of opioid peptides regulating proliferation of neurons and glia in the developing nervous system Brain Research. 542: 318-323. PMID 2029640 DOI: 10.1016/0006-8993(91)91585-O |
0.448 |
|
| 1991 |
Isayama T, Zagon IS. Localization of preproenkephalin A mRNA in the neonatal rat retina. Brain Research Bulletin. 27: 805-8. PMID 1786557 DOI: 10.1016/0361-9230(91)90212-3 |
0.398 |
|
| 1991 |
Zagon IS, Gibo DM, McLaughlin PJ. Zeta (ξ), a growth-related opioid receptor in developing rat cerebellum: identification and characterization Brain Research. 551: 28-35. PMID 1655161 DOI: 10.1016/0006-8993(91)90909-F |
0.422 |
|
| 1991 |
Isayama T, McLaughlin PJ, Zagon IS. Endogenous opioids regulate cell proliferation in the retina of developing rat. Brain Research. 544: 79-85. PMID 1649664 DOI: 10.1016/0006-8993(91)90887-2 |
0.485 |
|
| 1990 |
Zagon IS, McLaughlin PJ. Ultrastructural localization of enkephalin-like immunoreactivity in developing rat cerebellum Neuroscience. 34: 479-489. PMID 2333154 DOI: 10.1016/0306-4522(90)90156-X |
0.371 |
|
| 1990 |
Zagon IS, McLaughlin PJ. Opioid antagonist (naltrexone) stimulation of cell proliferation in human and animal neuroblastoma and human fibrosarcoma cells in culture Neuroscience. 37: 223-226. PMID 2243594 DOI: 10.1016/0306-4522(90)90207-K |
0.474 |
|
| 1990 |
Zagon IS, Gibo DM, McLaughlin PJ. Adult and developing human cerebella exhibit different profiles of opioid binding sites Brain Research. 523: 62-68. PMID 2169964 DOI: 10.1016/0006-8993(90)91635-T |
0.394 |
|
| 1990 |
Zagon IS, Goodman SR, McLaughlin PJ. Demonstration and characterization of zeta (ζ), a growth-related opioid receptor, in a neuroblastoma cell line Brain Research. 511: 181-186. PMID 2159355 DOI: 10.1016/0006-8993(90)90159-9 |
0.438 |
|
| 1990 |
Zagon IS, Gibo D, McLaughlin PJ. Expression of zeta (ζ), a growth-related opioid receptor, in metastatic adenocarcinoma of the human cerebellum Journal of the National Cancer Institute. 82: 325-327. PMID 2153842 DOI: 10.1093/Jnci/82.4.325 |
0.419 |
|
| 1990 |
Zagon IS, McLaughlin PJ. Endogenous opioids, opioids receptors, and cancer Cancer Journal. 3: 101-103. |
0.319 |
|
| 1989 |
Zagon IS. Endogenous opioid systems and neural cancer: transmission and scanning electron microscopic studies of murine neuroblastoma in tissue culture. Brain Research Bulletin. 21: 777-84. PMID 3219609 DOI: 10.1016/0361-9230(88)90046-9 |
0.467 |
|
| 1989 |
Hauser KF, McLaughlin PJ, Zagon IS. Endogenous opioid systems and the regulation of dendritic growth and spine formation. The Journal of Comparative Neurology. 281: 13-22. PMID 2925898 DOI: 10.1002/Cne.902810103 |
0.662 |
|
| 1989 |
Zagon IS. Endogenous opioids and neural cancer: an immunoelectron microscopic study. Brain Research Bulletin. 22: 1023-9. PMID 2790495 DOI: 10.1016/0361-9230(89)90015-4 |
0.462 |
|
| 1989 |
Zagon IS, McLaughlin PJ. Endogenous opioid systems regulate growth of neural tumor cells in culture Brain Research. 490: 14-25. PMID 2758319 DOI: 10.1016/0006-8993(89)90425-3 |
0.474 |
|
| 1989 |
Zagon IS, Zagon E, McLaughlin PJ. Opioids and the developing organism: A comprehensive bibliography, 1984-1988 Neuroscience and Biobehavioral Reviews. 13: 207-235. PMID 2691928 DOI: 10.1016/S0149-7634(89)80055-7 |
0.364 |
|
| 1989 |
Zagon IS, McLaughlin PJ. Naloxone modulates body and organ growth of rats: Dependency on the duration of opioid receptor blockade and stereospecificity Pharmacology, Biochemistry and Behavior. 33: 325-328. PMID 2554339 DOI: 10.1016/0091-3057(89)90508-X |
0.466 |
|
| 1989 |
Zagon IS, McLaughlin PJ. Opioid antagonist modulation of murine neuroblastoma: a profile of cell proliferation and opioid peptides and receptors Brain Research. 480: 16-28. PMID 2540873 DOI: 10.1016/0006-8993(89)91562-X |
0.486 |
|
| 1989 |
Zagon IS, Goodman SR, McLaughlin PJ. Characterization of zeta (zeta): a new opioid receptor involved in growth. Brain Research. 482: 297-305. PMID 2539884 DOI: 10.1016/0006-8993(89)91192-X |
0.437 |
|
| 1988 |
Zagon IS, Goodman SR, McLaughlin PJ. Characterization of opioid binding sites in murine neuroblastoma Brain Research. 449: 80-88. PMID 2899449 DOI: 10.1016/0006-8993(88)91026-8 |
0.325 |
|
| 1988 |
Zagon IS, McLaughlin P. Endogenous opioids and the growth regulation of a neural tumor. Life Sciences. 43: 1313-8. PMID 2845218 DOI: 10.1016/0024-3205(88)90586-3 |
0.47 |
|
| 1988 |
Hess GD, Zagon IS. Endogenous opioid systems and neural development: ultrastructural studies in the cerebellar cortex of infant and weanling rats. Brain Research Bulletin. 20: 473-8. PMID 2840175 DOI: 10.1016/0361-9230(88)90137-2 |
0.47 |
|
| 1987 |
Zagon IS, McLaughlin PJ. Endogenous opioid systems regulate cell proliferation in the developing rat brain. Brain Research. 412: 68-72. PMID 3607463 DOI: 10.1016/0006-8993(87)91440-5 |
0.472 |
|
| 1987 |
McLaughlin PJ, Zagon IS. Modulation of human neuroblastoma transplanted into nude mice by endogenous opioid systems Life Sciences. 41: 1465-1472. PMID 3041143 DOI: 10.1016/0024-3205(87)90711-9 |
0.469 |
|
| 1987 |
Hauser KF, McLaughlin PJ, Zagon IS. Endogenous opioids regulate dendritic growth and spine formation in developing rat brain. Brain Research. 416: 157-61. PMID 3040177 DOI: 10.1016/0006-8993(87)91509-5 |
0.649 |
|
| 1987 |
Zagon IS, McLaughlin PJ. Modulation of murine neuroblastoma in nude mice by opioid antagonists Journal of the National Cancer Institute. 78: 141-147. PMID 3025501 DOI: 10.1093/Jnci/78.1.141 |
0.444 |
|
| 1987 |
Zagon IS, McLaughlin PJ, Goodman SR, Rhodes RE. Opioid receptors and endogenous opioids in diverse human and animal cancers. Journal of the National Cancer Institute. 79: 1059-1065. DOI: 10.1093/Jnci/79.5.1059 |
0.444 |
|
| 1986 |
Zagon IS, Rhodes RE, McLaughlin PJ. Localization of enkephalin immunoreactivity in diverse tissues and cells of the developing and adult rat Cell and Tissue Research. 246: 561-565. PMID 3539353 DOI: 10.1007/Bf00215197 |
0.411 |
|
| 1986 |
Zagon IS, McLaughlin PJ. β-Funaltrexamine (β-FNA) and the regulation of body and brain development in rats Brain Research Bulletin. 17: 5-9. PMID 3019487 DOI: 10.1016/0361-9230(86)90155-3 |
0.382 |
|
| 1986 |
Zagon IS, McLaughlin PJ. Opioid antagonist-induced modulation of cerebral and hippocampal development: histological and morphometric studies Brain Research. 393: 233-246. PMID 3017514 DOI: 10.1016/0165-3806(86)90025-8 |
0.478 |
|
| 1986 |
Goodman SR, Zagon IS, Coleman DB, McLaughlin PJ. Spectrin expression in neuroblastoma cells. Brain Research Bulletin. 16: 597-602. PMID 2427173 DOI: 10.1016/0361-9230(86)90133-4 |
0.312 |
|
| 1986 |
Zagon I, McLaughlin P. Opioid antagonist (naltrexone) modulation of cerebellar development: histological and morphometric studies The Journal of Neuroscience. 6: 1424-1432. DOI: 10.1523/Jneurosci.06-05-01424.1986 |
0.482 |
|
| 1985 |
Zagon IS, Vaughn BV, McLaughlin PJ, Balaban CD. Localization of methadone in the brain of young rats by computer-assisted autoradiography. Neuroscience Research. 3: 1-19. PMID 4088543 DOI: 10.1016/0168-0102(85)90035-5 |
0.36 |
|
| 1985 |
Zagon IS, McLaughlin PJ. Opiate antagonist-induced regulation of organ development Physiology and Behavior. 34: 507-511. PMID 4011730 DOI: 10.1016/0031-9384(85)90041-1 |
0.393 |
|
| 1985 |
Zagon IS, McLaughlin PJ. Naltrexone's influence on neurobehavioral development Pharmacology, Biochemistry and Behavior. 22: 441-448. PMID 3991759 DOI: 10.1016/0091-3057(85)90046-2 |
0.369 |
|
| 1985 |
Zagon IS, Rhodes RE, McLaughlin PJ. Distribution of enkephalin immunoreactivity in germinative cells of developing rat cerebellum Science. 227: 1049-1051. PMID 3883485 DOI: 10.1126/Science.3883485 |
0.418 |
|
| 1985 |
Zagon IS, McLaughlin PJ. Stereospecific modulation of tumorigenicity by opioid antagonists European Journal of Pharmacology. 113: 115-120. PMID 2995053 DOI: 10.1016/0014-2999(85)90350-4 |
0.42 |
|
| 1985 |
Zagon IS, McLaughlin PJ. Endogenous opioids and brain development International Journal of Developmental Neuroscience. 3: 425-425. DOI: 10.1016/0736-5748(85)90103-0 |
0.395 |
|
| 1984 |
Zagon IS, McLaughlin PJ. Naltrexone modulates body and brain development in rats: A role for endogenous opioid systems in growth Life Sciences. 35: 2057-2064. PMID 6092812 DOI: 10.1016/0024-3205(84)90563-0 |
0.447 |
|
| 1984 |
Zagon IS, McLaughlin PJ. Duration of opiate receptor blockade determines tumorigenic response in mice with neuroblastoma: A role for endogenous opioid systems in cancer Life Sciences. 35: 409-416. PMID 6087062 DOI: 10.1016/0024-3205(84)90651-9 |
0.403 |
|
| 1984 |
Zagon I, McLaughlin P, Goodman S. Localization of spectrin in mammalian brain The Journal of Neuroscience. 4: 3089-3100. DOI: 10.1523/Jneurosci.04-12-03089.1984 |
0.308 |
|
| 1983 |
Zagon IS, McLaughlin PJ. Naltrexone modulates tumor response in mice with neuroblastoma Science. 221: 671-673. PMID 6867737 DOI: 10.1126/Science.6867737 |
0.364 |
|
| 1983 |
Zagon IS, McLaughlin PJ. Opioid antagonists inhibit the growth of metastatic murine neuroblastoma Cancer Letters. 21: 89-94. PMID 6640516 DOI: 10.1016/0304-3835(83)90087-3 |
0.402 |
|
| 1983 |
Zagon IS, Mclaughlin PJ. Increased brain size and cellular content in infant rats treated with an opiate antagonist Science. 221: 1179-1180. PMID 6612331 DOI: 10.1126/Science.6612331 |
0.407 |
|
| 1983 |
Zagon IS, McLaughlin PJ. Naltrexone modulates growth in infant rats Life Sciences. 33: 2449-2454. PMID 6316064 DOI: 10.1016/0024-3205(83)90639-2 |
0.428 |
|
| 1982 |
Zagon IS, McLaughlin PJ. Neuronal cell deficits following maternal exposure to methadone in rats Experientia. 38: 1214-1216. PMID 7140924 DOI: 10.1007/Bf01959747 |
0.31 |
|
| 1981 |
Zagon IS, McLaughlin PJ. Enhanced sensitivity to methadone in adult rats perinatally exposed to methadone Life Sciences. 29: 1137-1142. PMID 7289777 DOI: 10.1016/0024-3205(81)90202-2 |
0.309 |
|
| 1981 |
Zagon IS, McLaughlin PJ. Heroin prolongs survival time and retards tumor growth in mice with neuroblastoma Brain Research Bulletin. 7: 25-32. PMID 7272785 DOI: 10.1016/0361-9230(81)90094-0 |
0.321 |
|
| 1981 |
Zagon IS, McLaughlin PJ. Naloxone prolongs the survival time of mice treated with neuroblastoma Life Sciences. 28: 1095-1102. PMID 7231040 DOI: 10.1016/0024-3205(81)90686-X |
0.33 |
|
| 1981 |
Zagon IS, McLaughlin PJ. Withdrawal-like symptoms in young and adult rats maternally exposed to methadone Pharmacology, Biochemistry and Behavior. 15: 887-894. PMID 7198796 DOI: 10.1016/0091-3057(81)90049-6 |
0.335 |
|
| 1981 |
Zagon IS, McLaughlin PJ. Nucleic acids and protein in brains and cerebella of rats transplacentally exposed to ethylnitrosourea Brain Research Bulletin. 6: 355-360. PMID 6166356 DOI: 10.1016/S0361-9230(81)80003-2 |
0.304 |
|
| 1980 |
McLaughlin PJ, Zagon IS. Body and organ development of young rats maternally exposed to methadone. Biology of the Neonate. 38: 185-96. PMID 7407276 DOI: 10.1159/000241363 |
0.311 |
|
| 1980 |
Zagon IS, McLaughlin PJ. Protracted analgesia in young and adult rats maternally exposed to methadone Experientia. 36: 329-330. PMID 7371790 DOI: 10.1007/Bf01952306 |
0.314 |
|
| 1979 |
Zagon IS, Mclaughlin PJ, Thompson CI. Development of motor activity in young rats following perinatal methadone exposure Pharmacology, Biochemistry and Behavior. 10: 743-749. PMID 493289 DOI: 10.1016/0091-3057(79)90327-7 |
0.346 |
|
| 1979 |
Zagon IS, McLaughlin PJ. Morphological identification and biochemical characterization of isolated brain cell nuclei from the developing rat cerebellum. Brain Research. 170: 443-57. PMID 466423 DOI: 10.1016/0006-8993(79)90963-6 |
0.32 |
|
| 1978 |
Zagon IS, McLaughlin PJ. Perinatal methadone exposure and its influence on the behavioral ontogeny of rats Pharmacology, Biochemistry and Behavior. 9: 665-672. PMID 733856 DOI: 10.1016/0091-3057(78)90219-8 |
0.335 |
|
| 1978 |
Zagon IS, McLaughlin PJ. Perinatal methadone exposure and brain development: A biochemical study Journal of Neurochemistry. 31: 49-54. PMID 671039 DOI: 10.1111/J.1471-4159.1978.Tb12431.X |
0.324 |
|
| 1978 |
Zagon IS, Schengrund CL. Neuronal and non-neuronal properties of neuroblastoma cells Experimental Cell Research. 114: 159-165. PMID 77786 DOI: 10.1016/0014-4827(78)90048-4 |
0.317 |
|
| 1977 |
Zagon IS, McLaughlin PJ. Methadone and brain development Experientia. 33: 1486-1487. PMID 923719 DOI: 10.1007/Bf01918824 |
0.319 |
|
| 1977 |
Zagon IS, McLaughlin PJ. Effect of chronic maternal methadone exposure on perinatal development Neonatology. 31: 271-282. PMID 911959 DOI: 10.1159/000240975 |
0.327 |
|
| 1977 |
Zagon IS, McLaughlin PJ. Effects of chronic morphine administration on pregnant rats and their offspring Pharmacology. 15: 302-310. PMID 896945 DOI: 10.1159/000136703 |
0.35 |
|
| 1977 |
Zagon IS, McLaughlin PJ. The effects of different schedules of methadone treatment on rat brain development Experimental Neurology. 56: 538-552. PMID 885202 DOI: 10.1016/0014-4886(77)90320-X |
0.364 |
|
| 1977 |
Zagon IS, McLaughlin PJ. Morphine and brain growth retardation in the rat Pharmacology. 15: 276-282. PMID 866403 DOI: 10.1159/000136699 |
0.368 |
|
| 1977 |
Zagon IS, Lasher RS. A modification of the Bodian technique for embedded, frozen, and cultured nervous tissue. Transactions of the American Microscopical Society. 96: 91-6. PMID 66794 DOI: 10.2307/3225969 |
0.644 |
|
| 1975 |
Zagon IS. Prolonged gestation and cerebellar development in the rat. Experimental Neurology. 46: 69-77. PMID 1109343 DOI: 10.1016/0014-4886(75)90032-1 |
0.352 |
|
| 1972 |
Lasher RS, Zagon IS. The effect of potassium on neuronal differentiation in cultures of dissociated newborn rat cerebellum. Brain Research. 41: 482-8. PMID 5038341 DOI: 10.1016/0006-8993(72)90521-5 |
0.649 |
|
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