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William Shain, Ph.D. - Publications

Affiliations: 
Neurological Surgery, Bioengineering University of Washington, Seattle, Seattle, WA 
Area:
Tissue histology, Reactive tissue response, Hydrocephalus
Website:
http://neurosurgery.washington.edu/education/faculty/researchbios/shain.asp
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51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Dryg I, Xie Y, Bergmann M, Urban G, Shain W, Hofmann UG. Long-termmonitoring of gliotic sheathing of ultrathin entropic coated brain microprobes with fiber-based optical coherence tomography. Journal of Neural Engineering. PMID 33657543 DOI: 10.1088/1741-2552/abebc2  0.671
2017 Hanak BW, Hsieh CY, Donaldson W, Browd SR, Lau KKS, Shain W. Reduced cell attachment to poly(2-hydroxyethyl methacrylate)-coated ventricular catheters in vitro. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 28631360 DOI: 10.1002/Jbm.B.33915  0.317
2016 Hanak BW, Ross EF, Harris CA, Browd SR, Shain W. Toward a better understanding of the cellular basis for cerebrospinal fluid shunt obstruction: report on the construction of a bank of explanted hydrocephalus devices. Journal of Neurosurgery. Pediatrics. 1-11. PMID 27035548 DOI: 10.3171/2016.2.Peds15531  0.372
2016 Xu Y, Megjhani M, Trett K, Shain W, Roysam B, Han Z. Unsupervised Profiling of Microglial Arbor Morphologies and Distribution Using a Nonparametric Bayesian Approach Ieee Journal On Selected Topics in Signal Processing. 10: 115-129. DOI: 10.1109/Jstsp.2015.2505660  0.33
2015 Harris C, Pearson K, Hadley K, Zhu S, Browd S, Hanak BW, Shain W. Fabrication of three-dimensional hydrogel scaffolds for modeling shunt failure by tissue obstruction in hydrocephalus. Fluids and Barriers of the Cns. 12: 26. PMID 26578355 DOI: 10.1186/S12987-015-0023-9  0.337
2015 Kulkarni PM, Barton E, Savelonas M, Padmanabhan R, Lu Y, Trett K, Shain W, Leasure JL, Roysam B. Quantitative 3-D analysis of GFAP labeled astrocytes from fluorescence confocal images. Journal of Neuroscience Methods. 246: 38-51. PMID 25745860 DOI: 10.1016/J.Jneumeth.2015.02.014  0.31
2015 Megjhani M, Rey-Villamizar N, Merouane A, Lu Y, Mukherjee A, Trett K, Chong P, Harris C, Shain W, Roysam B. Population-scale three-dimensional reconstruction and quantitative profiling of microglia arbors. Bioinformatics (Oxford, England). 31: 2190-8. PMID 25701570 DOI: 10.1093/Bioinformatics/Btv109  0.347
2015 Lu Y, Carin L, Coifman R, Shain W, Roysam B. Quantitative arbor analytics: unsupervised harmonic co-clustering of populations of brain cell arbors based on L-measure. Neuroinformatics. 13: 47-63. PMID 25086878 DOI: 10.1007/S12021-014-9237-2  0.323
2014 Rey-Villamizar N, Somasundar V, Megjhani M, Xu Y, Lu Y, Padmanabhan R, Trett K, Shain W, Roysam B. Large-scale automated image analysis for computational profiling of brain tissue surrounding implanted neuroprosthetic devices using Python. Frontiers in Neuroinformatics. 8: 39. PMID 24808857 DOI: 10.3389/Fninf.2014.00039  0.351
2012 Gage GJ, Kipke DR, Shain W. Whole animal perfusion fixation for rodents. Journal of Visualized Experiments : Jove. PMID 22871843 DOI: 10.3791/3564  0.341
2012 Smith KL, Herron B, Dowell-Mesfin N, Wu H, Kim SJ, Shain W, Hynd MR. Knockdown of cortical transthyretin expression around implanted neural prosthetic devices using intraventricular siRNA injection in the brain. Journal of Neuroscience Methods. 203: 398-406. PMID 21978485 DOI: 10.1016/J.Jneumeth.2011.09.023  0.361
2011 Lewitus DY, Smith KL, Shain W, Bolikal D, Kohn J. The fate of ultrafast degrading polymeric implants in the brain. Biomaterials. 32: 5543-50. PMID 21609850 DOI: 10.1016/J.Biomaterials.2011.04.052  0.354
2011 Tsai CL, Lister JP, Bjornsson CS, Smith K, Shain W, Barnes CA, Roysam B. Robust, globally consistent and fully automatic multi-image registration and montage synthesis for 3-D multi-channel images. Journal of Microscopy. 243: 154-71. PMID 21361958 DOI: 10.1111/J.1365-2818.2011.03489.X  0.312
2011 Lewitus D, Smith KL, Shain W, Kohn J. Ultrafast resorbing polymers for use as carriers for cortical neural probes. Acta Biomaterialia. 7: 2483-91. PMID 21345383 DOI: 10.1016/J.Actbio.2011.02.027  0.31
2011 Frampton JP, Hynd MR, Shuler ML, Shain W. Fabrication and optimization of alginate hydrogel constructs for use in 3D neural cell culture. Biomedical Materials (Bristol, England). 6: 015002. PMID 21205998 DOI: 10.1088/1748-6041/6/1/015002  0.341
2010 Jun SB, Smith KL, Shain W, Dowell-Mesfin NM, Kim SJ, Hynd MR. Optical monitoring of neural networks evoked by focal electrical stimulation on microelectrode arrays using FM dyes. Medical & Biological Engineering & Computing. 48: 933-40. PMID 20490941 DOI: 10.1007/S11517-010-0628-8  0.305
2010 Frampton JP, Hynd MR, Shuler ML, Shain W. Effects of glial cells on electrode impedance recorded from neuralprosthetic devices in vitro. Annals of Biomedical Engineering. 38: 1031-47. PMID 20336824 DOI: 10.1007/S10439-010-9911-Y  0.415
2009 Jhaveri SJ, Hynd MR, Dowell-Mesfin N, Turner JN, Shain W, Ober CK. Release of nerve growth factor from HEMA hydrogel-coated substrates and its effect on the differentiation of neural cells. Biomacromolecules. 10: 174-83. PMID 19061335 DOI: 10.1021/Bm801101E  0.387
2008 Frampton JP, Shuler ML, Shain W, Hynd MR. Biomedical Technologies for in vitro Screening and Controlled Delivery of Neuroactive Compounds. Central Nervous System Agents in Medicinal Chemistry. 8: 203-219. PMID 19079777 DOI: 10.2174/187152408785699613  0.337
2008 Retterer ST, Smith KL, Bjornsson CS, Turner JN, Isaacson MS, Shain W. Constant pressure fluid infusion into rat neocortex from implantable microfluidic devices. Journal of Neural Engineering. 5: 385-91. PMID 18827310 DOI: 10.1088/1741-2560/5/4/003  0.42
2008 Seggio AM, Ellison KS, Hynd MR, Shain W, Thompson DM. Cryopreservation of transfected primary dorsal root ganglia neurons. Journal of Neuroscience Methods. 173: 67-73. PMID 18639343 DOI: 10.1016/J.Jneumeth.2008.05.017  0.306
2008 Jun SB, Hynd MR, Dowell-Mesfin NM, Al-Kofahi Y, Roysam B, Shain W, Kim SJ. Modulation of cultured neural networks using neurotrophin release from hydrogel-coated microelectrode arrays. Journal of Neural Engineering. 5: 203-13. PMID 18477815 DOI: 10.1088/1741-2560/5/2/011  0.365
2008 Bjornsson CS, Lin G, Al-Kofahi Y, Narayanaswamy A, Smith KL, Shain W, Roysam B. Associative image analysis: a method for automated quantification of 3D multi-parameter images of brain tissue. Journal of Neuroscience Methods. 170: 165-78. PMID 18294697 DOI: 10.1016/J.Jneumeth.2007.12.024  0.389
2007 Williams JC, Hippensteel JA, Dilgen J, Shain W, Kipke DR. Complex impedance spectroscopy for monitoring tissue responses to inserted neural implants. Journal of Neural Engineering. 4: 410-23. PMID 18057508 DOI: 10.1088/1741-2560/4/4/007  0.325
2007 Frampton JP, Hynd MR, Williams JC, Shuler ML, Shain W. Three-dimensional hydrogel cultures for modeling changes in tissue impedance around microfabricated neural probes. Journal of Neural Engineering. 4: 399-409. PMID 18057507 DOI: 10.1088/1741-2560/4/4/006  0.423
2007 Hynd MR, Frampton JP, Dowell-Mesfin N, Turner JN, Shain W. Directed cell growth on protein-functionalized hydrogel surfaces. Journal of Neuroscience Methods. 162: 255-63. PMID 17368788 DOI: 10.1016/J.Jneumeth.2007.01.024  0.336
2007 Jun SB, Hynd MR, Dowell-Mesfin N, Smith KL, Turner JN, Shain W, Kim SJ. Low-density neuronal networks cultured using patterned poly-l-lysine on microelectrode arrays. Journal of Neuroscience Methods. 160: 317-26. PMID 17049614 DOI: 10.1016/J.Jneumeth.2006.09.009  0.326
2007 Al-Kofahi Y, Lin G, Bjornsson C, Smith K, Shain W, Roysam B. Computer-Aided Classification of Cells in Complex Brain Tissue from 5-Channel 3-D Confocal Datasets Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607074764  0.352
2006 Bjornsson CS, Oh SJ, Al-Kofahi YA, Lim YJ, Smith KL, Turner JN, De S, Roysam B, Shain W, Kim SJ. Effects of insertion conditions on tissue strain and vascular damage during neuroprosthetic device insertion. Journal of Neural Engineering. 3: 196-207. PMID 16921203 DOI: 10.1088/1741-2560/3/3/002  0.382
2005 Spataro L, Dilgen J, Retterer S, Spence AJ, Isaacson M, Turner JN, Shain W. Dexamethasone treatment reduces astroglia responses to inserted neuroprosthetic devices in rat neocortex. Experimental Neurology. 194: 289-300. PMID 16022859 DOI: 10.1016/J.Expneurol.2004.08.037  0.371
2005 Ma SH, Lepak LA, Hussain RJ, Shain W, Shuler ML. An endothelial and astrocyte co-culture model of the blood-brain barrier utilizing an ultra-thin, nanofabricated silicon nitride membrane. Lab On a Chip. 5: 74-85. PMID 15616743 DOI: 10.1039/B405713A  0.325
2005 Narasimha-Iyer H, Dowell-Mesfin NM, Abdul-Karim M, Roysam B, Turner J, Shain W. Associative Multiple-Label Image Analysis Method for Synapse Identification in Neuronal Cultures: Application to Comparative Analysis of Synapse Formation Efficiency & Distribution on Smooth and Topographically Modified Surfaces Microscopy and Microanalysis. 11. DOI: 10.1017/S1431927605501879  0.306
2004 Dowell-Mesfin NM, Abdul-Karim MA, Turner AM, Schanz S, Craighead HG, Roysam B, Turner JN, Shain W. Topographically modified surfaces affect orientation and growth of hippocampal neurons. Journal of Neural Engineering. 1: 78-90. PMID 15876626 DOI: 10.1088/1741-2560/1/2/003  0.327
2004 Retterer ST, Smith KL, Bjornsson CS, Neeves KB, Spence AJ, Turner JN, Shain W, Isaacson MS. Model neural prostheses with integrated microfluidics: a potential intervention strategy for controlling reactive cell and tissue responses. Ieee Transactions On Bio-Medical Engineering. 51: 2063-73. PMID 15536908 DOI: 10.1109/Tbme.2004.834288  0.416
2004 James CD, Spence AJ, Dowell-Mesfin NM, Hussain RJ, Smith KL, Craighead HG, Isaacson MS, Shain W, Turner JN. Extracellular recordings from patterned neuronal networks using planar microelectrode arrays. Ieee Transactions On Bio-Medical Engineering. 51: 1640-8. PMID 15376512 DOI: 10.1109/Tbme.2004.827252  0.312
2003 Szarowski DH, Andersen MD, Retterer S, Spence AJ, Isaacson M, Craighead HG, Turner JN, Shain W. Brain responses to micro-machined silicon devices. Brain Research. 983: 23-35. PMID 12914963 DOI: 10.1016/S0006-8993(03)03023-3  0.352
2003 Shain W, Spataro L, Dilgen J, Haverstick K, Retterer S, Isaacson M, Saltzman M, Turner JN. Controlling cellular reactive responses around neural prosthetic devices using peripheral and local intervention strategies. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 11: 186-8. PMID 12899270 DOI: 10.1109/Tnsre.2003.814800  0.331
2002 Kam L, Shain W, Turner JN, Bizios R. Selective adhesion of astrocytes to surfaces modified with immobilized peptides. Biomaterials. 23: 511-5. PMID 11761172 DOI: 10.1016/S0142-9612(01)00133-8  0.308
2002 Russo AP, Apoga D, Dowell N, Shain W, Turner AMP, Craighead HG, Hoch HC, Turner JN. Microfabricated plastic devices from silicon using soft intermediates Biomedical Microdevices. 4: 277-283. DOI: 10.1023/A:1020902106144  0.318
2001 Kam L, Shain W, Turner JN, Bizios R. Axonal outgrowth of hippocampal neurons on micro-scale networks of polylysine-conjugated laminin. Biomaterials. 22: 1049-54. PMID 11352086 DOI: 10.1016/S0142-9612(00)00352-5  0.319
2000 Turner AM, Dowell N, Turner SW, Kam L, Isaacson M, Turner JN, Craighead HG, Shain W. Attachment of astroglial cells to microfabricated pillar arrays of different geometries. Journal of Biomedical Materials Research. 51: 430-41. PMID 10880086 DOI: 10.1002/1097-4636(20000905)51:3<430::Aid-Jbm18>3.0.Co;2-C  0.361
1999 Kam L, Shain W, Turner JN, Bizios R. Correlation of astroglial cell function on micro-patterned surfaces with specific geometric parameters. Biomaterials. 20: 2343-50. PMID 10614940 DOI: 10.1016/S0142-9612(99)00163-5  0.336
1999 Shain W, Kayali S, Szarowski D, Davis-Cox M, Ancin H, Bhattacharjya AK, Roysam B, Turner JN. Application and Quantitative Validation of Computer-Automated Three-Dimensional Counting of Cell Nuclei. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 5: 106-119. PMID 10341010 DOI: 10.1017/S1431927699000069  0.31
1999 Turner JN, Shain W, Szarowski DH, Andersen M, Martins S, Isaacson M, Craighead H. Cerebral astrocyte response to micromachined silicon implants. Experimental Neurology. 156: 33-49. PMID 10192775 DOI: 10.1006/Exnr.1998.6983  0.44
1999 Turner JN, Shain W, Szarowski DH, Lasek S, Sipple B, Pace C, Al-Kafahi K, Can A, Roysam B. Confocal light microscopy of brain cells and tissue: Image analysis and quantitation Acta Histochemica Et Cytochemica. 32: 5-11. DOI: 10.1267/Ahc.32.5  0.383
1998 Craighead HG, Turner SW, Davis RC, James C, Perez AM, St. John PM, Isaacson MS, Kam L, Shain W, Turner JN, Banker G. Chemical and Topographical Surface Modification for Control of Central Nervous System Cell Adhesion Biomedical Microdevices. 1: 49-64. DOI: 10.1023/A:1009982306118  0.303
1997 St John PM, Kam L, Turner SW, Craighead HG, Issacson M, Turner JN, Shain W. Preferential glial cell attachment to microcontact printed surfaces. Journal of Neuroscience Methods. 75: 171-7. PMID 9288649 DOI: 10.1016/S0165-0270(97)00069-1  0.303
1997 Turner S, Kam L, Isaacson M, Craighead HG, Shain W, Turner J. Cell attachment on silicon nanostructures Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 15: 2848-2854. DOI: 10.1116/1.589742  0.326
1997 Turner JN, Shain W, Szarowski DH, Anderson M, Martins S, Davis R, Craighead HG, Isaacson M. Tissue Compatibility of Silicon Microfabricated Probes Inserted into the Brain Microscopy and Microanalysis. 3: 289-290. DOI: 10.1017/S1431927600008333  0.355
1994 Davis-Cox MI, Turner JN, Szarowski D, Shain W. Phorbol ester-stimulated stellation in primary cultures of astrocytes from different brain regions. Microscopy Research and Technique. 29: 319-27. PMID 7841503 DOI: 10.1002/Jemt.1070290409  0.339
1988 Madelian V, Silliman S, Shain W. Adenosine stimulates cAMP-mediated taurine release from LRM55 glial cells. Journal of Neuroscience Research. 20: 176-81. PMID 2459404 DOI: 10.1002/Jnr.490200205  0.304
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