Lauren Mifflin - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li W, Shan B, Zou C, Wang H, Zhang MM, Zhu H, Naito MG, Xu D, Manuel VJ, Mifflin L, Hou Z, Ravits J, Yuan J. Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response. Cell Research. PMID 35661830 DOI: 10.1038/s41422-022-00673-3  0.579
2021 Wang H, Qi W, Zou C, Xie Z, Zhang M, Naito MG, Mifflin L, Liu Z, Najafov A, Pan H, Shan B, Li Y, Zhu ZJ, Yuan J. NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation. Nature Communications. 12: 4826. PMID 34376696 DOI: 10.1038/s41467-021-25157-7  0.517
2021 Mifflin L, Hu Z, Dufort C, Hession CC, Walker AJ, Niu K, Zhu H, Liu N, Liu JS, Levin JZ, Stevens B, Yuan J, Zou C. A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33766915 DOI: 10.1073/pnas.2025102118  0.581
2020 Zou C, Mifflin L, Hu Z, Zhang T, Shan B, Wang H, Xing X, Zhu H, Adiconis X, Levin JZ, Li F, Liu CF, Liu JS, Yuan J. Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease. Cell Reports. 33: 108447. PMID 33296651 DOI: 10.1016/j.celrep.2020.108447  0.523
2020 Najafov A, Luu HS, Mookhtiar AK, Mifflin L, Xia HG, Amin PP, Ordureau A, Wang H, Yuan J. RIPK1 Promotes Energy Sensing by the mTORC1 Pathway. Molecular Cell. PMID 33271062 DOI: 10.1016/j.molcel.2020.11.008  0.506
2020 Xu D, Zhao H, Jin M, Zhu H, Shan B, Geng J, Dziedzic SA, Amin P, Mifflin L, Naito MG, Najafov A, Xing J, Yan L, Liu J, Qin Y, et al. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis. Nature. PMID 32968279 DOI: 10.1038/s41586-020-2757-z  0.522
2020 Mifflin L, Ofengeim D, Yuan J. Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target. Nature Reviews. Drug Discovery. PMID 32669658 DOI: 10.1038/S41573-020-0071-Y  0.607
2018 Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, et al. TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell. PMID 30146158 DOI: 10.1016/J.Cell.2018.07.041  0.612
2017 Ofengeim D, Mazzitelli S, Ito Y, DeWitt JP, Mifflin L, Zou C, Das S, Adiconis X, Chen H, Zhu H, Kelliher MA, Levin JZ, Yuan J. RIPK1 mediates a disease-associated microglial response in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 28904096 DOI: 10.1073/Pnas.1714175114  0.633
2011 Ecke LE, Cleck JN, White P, Schug J, Mifflin L, Blendy JA. CREB-mediated alterations in the amygdala transcriptome: coordinated regulation of immune response genes following cocaine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1111-26. PMID 21138621 DOI: 10.1017/S1461145710001392  0.512
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