| Year |
Citation |
Score |
| 2024 |
Cámara-Checa A, Rubio-Alarcón M, Dago M, Crespo-García T, Rapún J, Marín M, Tamargo J, Gómez R, Caballero R, Delpón E. Reply to Benndorff and DiFrancesco: Reliable human HCN4 single-channel recordings using the cell-attached configuration in expression systems. Proceedings of the National Academy of Sciences of the United States of America. 121: e2402992121. PMID 38588416 DOI: 10.1073/pnas.2402992121 |
0.369 |
|
| 2023 |
Cámara-Checa A, Perin F, Rubio-Alarcón M, Dago M, Crespo-García T, Rapún J, Marín M, Cebrián J, Gómez R, Bermúdez-Jiménez F, Monserrat L, Tamargo J, Caballero R, Jiménez-Jáimez J, Delpón E. A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305135120. PMID 38032931 DOI: 10.1073/pnas.2305135120 |
0.414 |
|
| 2020 |
Tinaquero D, Crespo-García T, Utrilla RG, Nieto-Marín P, González-Guerra A, Rubio-Alarcón M, Cámara-Checa A, Dago M, Matamoros M, Pérez-Hernández M, Tamargo M, Cebrián J, Jalife J, Tamargo J, Bernal JA, et al. The p.P888L SAP97 polymorphism increases the transient outward current (I) and abbreviates the action potential duration and the QT interval. Scientific Reports. 10: 10707. PMID 32612162 DOI: 10.1038/S41598-020-67109-Z |
0.338 |
|
| 2018 |
Pérez-Hernández M, Matamoros M, Alfayate S, Nieto-Marín P, Utrilla RG, Tinaquero D, de Andrés R, Crespo T, Ponce-Balbuena D, Willis BC, Jiménez-Vazquez EN, Guerrero-Serna G, da Rocha AM, Campbell K, Herron TJ, ... ... Tamargo J, et al. Brugada syndrome trafficking-defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channels. Jci Insight. 3. PMID 30232268 DOI: 10.1172/Jci.Insight.96291 |
0.346 |
|
| 2018 |
Tamargo J, Caballero R, Delpón E. New Therapeutic Approaches for the Treatment of Hyperkalemia in Patients Treated with Renin-Angiotensin-Aldosterone System Inhibitors. Cardiovascular Drugs and Therapy. 32: 99-119. PMID 29372448 DOI: 10.1007/S10557-017-6767-5 |
0.312 |
|
| 2017 |
Utrilla RG, Nieto-Marín P, Alfayate S, Tinaquero D, Matamoros M, Pérez-Hernández M, Sacristán S, Ondo L, de Andrés R, Díez-Guerra FJ, Tamargo J, Delpón E, Caballero R. Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone. Frontiers in Physiology. 8: 903. PMID 29184507 DOI: 10.3389/Fphys.2017.00903 |
0.344 |
|
| 2017 |
Caballero R, Utrilla RG, Amorós I, Matamoros M, Pérez-Hernández M, Tinaquero D, Alfayate S, Nieto-Marín P, Guerrero-Serna G, Liu QH, Ramos-Mondragón R, Ponce-Balbuena D, Herron T, Campbell KF, Filgueiras-Rama D, ... ... Tamargo J, et al. Tbx20 controls the expression of the KCNH2 gene and of hERG channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049825 DOI: 10.1073/Pnas.1612383114 |
0.335 |
|
| 2017 |
Tamargo J, Ruilope LM. Investigational calcium channel blockers for the treatment of hypertension. Expert Opinion On Investigational Drugs. 25: 1295-1309. PMID 27696904 DOI: 10.1080/13543784.2016.1241764 |
0.332 |
|
| 2016 |
Rivera-Torres J, Calvo CJ, Llach A, Guzmán-Martínez G, Caballero R, González-Gómez C, Jiménez-Borreguero LJ, Guadix JA, Osorio FG, López-Otín C, Herraiz-Martínez A, Cabello N, Vallmitjana A, Benítez R, Gordon LB, ... ... Tamargo J, et al. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799555 DOI: 10.1073/Pnas.1603754113 |
0.309 |
|
| 2016 |
Matamoros M, Pérez-Hernández M, Guerrero-Serna G, Amorós I, Barana A, Núñez M, Ponce-Balbuena D, Sacristán S, Gómez R, Tamargo J, Caballero R, Jalife J, Delpón E. Nav1.5 N-terminal domain binding to α1-syntrophin increases membrane density of human Kir2.1, Kir2.2 and Nav1.5 channels. Cardiovascular Research. 110: 279-90. PMID 26786162 DOI: 10.1093/Cvr/Cvw009 |
0.489 |
|
| 2016 |
Pérez-Hernández M, Matamoros M, Barana A, Amorós I, Gómez R, Núñez M, Sacristán S, Pinto Á, Fernández-Avilés F, Tamargo J, Delpón E, Caballero R. Pitx2c increases in atrial myocytes from chronic atrial fibrillation patients enhancing IKs and decreasing ICa,L. Cardiovascular Research. 109: 431-41. PMID 26714926 DOI: 10.1093/Cvr/Cvv280 |
0.495 |
|
| 2015 |
Ferrari R, Bertini M, Blomstrom-Lundqvist C, Dobrev D, Kirchhof P, Pappone C, Ravens U, Tamargo J, Tavazzi L, Vicedomini GG. An update on atrial fibrillation in 2014: From pathophysiology to treatment. International Journal of Cardiology. 203: 22-29. PMID 26490502 DOI: 10.1016/J.Ijcard.2015.10.089 |
0.325 |
|
| 2015 |
Tamargo J, Caballero R, Delpón E. Cancer chemotherapy and cardiac arrhythmias: a review. Drug Safety. 38: 129-52. PMID 25577497 DOI: 10.1007/S40264-014-0258-4 |
0.317 |
|
| 2014 |
Tamargo J, Duarte J, Ruilope LM. New antihypertensive drugs under development. Current Medicinal Chemistry. 22: 305-342. PMID 25386825 DOI: 10.2174/0929867321666141106113018 |
0.31 |
|
| 2014 |
Gómez R, Caballero R, Barana A, Amorós I, De Palm SH, Matamoros M, Núñez M, Pérez-Hernández M, Iriepa I, Tamargo J, Delpón E. Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents. Cardiovascular Research. 104: 337-46. PMID 25205296 DOI: 10.1093/Cvr/Cvu203 |
0.514 |
|
| 2014 |
Barana A, Matamoros M, Dolz-Gaitón P, Pérez-Hernández M, Amorós I, Núñez M, Sacristán S, Pedraz Á, Pinto Á, Fernández-Avilés F, Tamargo J, Delpón E, Caballero R. Chronic atrial fibrillation increases microRNA-21 in human atrial myocytes decreasing L-type calcium current. Circulation. Arrhythmia and Electrophysiology. 7: 861-8. PMID 25107449 DOI: 10.1161/Circep.114.001709 |
0.32 |
|
| 2014 |
Tamargo J, Solini A, Ruilope LM. Comparison of agents that affect aldosterone action. Seminars in Nephrology. 34: 285-306. PMID 25016400 DOI: 10.1016/J.Semnephrol.2014.04.005 |
0.326 |
|
| 2013 |
Zarzuelo MJ, Gómez-Guzmán M, Jiménez R, Quintela AM, Romero M, Sánchez M, Zarzuelo A, Tamargo J, Pérez-VizcaÃno F, Duarte J. Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension. Cardiovascular Research. 99: 622-31. PMID 23752977 DOI: 10.1093/Cvr/Cvt152 |
0.31 |
|
| 2013 |
Amorós I, Dolz-Gaitón P, Gómez R, Matamoros M, Barana A, de la Fuente MG, Núñez M, Pérez-Hernández M, Moraleda I, Gálvez E, Iriepa I, Tamargo J, Caballero R, Delpón E. Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore. Biochemical Pharmacology. 86: 267-78. PMID 23648307 DOI: 10.1016/J.Bcp.2013.04.023 |
0.509 |
|
| 2013 |
Núñez L, Barana A, Amorós I, de la Fuente MG, Dolz-Gaitón P, Gómez R, Rodríguez-García I, Mosquera I, Monserrat L, Delpón E, Caballero R, Castro-Beiras A, Tamargo J. p.D1690N Nav1.5 rescues p.G1748D mutation gating defects in a compound heterozygous Brugada syndrome patient. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 264-72. PMID 23085483 DOI: 10.1016/J.Hrthm.2012.10.025 |
0.431 |
|
| 2013 |
González de la Fuente M, Barana A, Gómez R, Amorós I, Dolz-Gaitón P, Sacristán S, Atienza F, Pita A, Pinto Á, Fernández-Avilés F, Caballero R, Tamargo J, Delpón E. Chronic atrial fibrillation up-regulates β1-Adrenoceptors affecting repolarizing currents and action potential duration. Cardiovascular Research. 97: 379-88. PMID 23060133 DOI: 10.1093/Cvr/Cvs313 |
0.469 |
|
| 2013 |
Caballero R, Matamoros M, Perez-Hernandez M, Dolz-Gaiton P, Barana A, Amoros I, Nunez M, Gonzalez De La Fuente M, Tamargo J, Delpon E. Human cardiac Kir2.1, but not Kir2.3, channel expression is regulated by Nav1.5 European Heart Journal. 34: P5019-P5019. DOI: 10.1093/Eurheartj/Eht310.P5019 |
0.324 |
|
| 2012 |
Tamargo J, Capucci A, Mabo P. Safety of flecainide. Drug Safety. 35: 273-89. PMID 22435343 DOI: 10.2165/11599950-000000000-00000 |
0.331 |
|
| 2012 |
Gómez-Guzmán M, Jiménez R, Sánchez M, Zarzuelo MJ, Galindo P, Quintela AM, López-Sepúlveda R, Romero M, Tamargo J, Vargas F, Pérez-VizcaÃno F, Duarte J. Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension. Free Radical Biology & Medicine. 52: 70-9. PMID 22001745 DOI: 10.1016/J.Freeradbiomed.2011.09.015 |
0.303 |
|
| 2011 |
Zarzuelo MJ, Jiménez R, Galindo P, Sánchez M, Nieto A, Romero M, Quintela AM, López-Sepúlveda R, Gómez-Guzmán M, Bailón E, RodrÃguez-Gómez I, Zarzuelo A, Gálvez J, Tamargo J, Pérez-VizcaÃno F, et al. Antihypertensive effects of peroxisome proliferator-activated receptor-β activation in spontaneously hypertensive rats. Hypertension. 58: 733-43. PMID 21825230 DOI: 10.1161/Hypertensionaha.111.174490 |
0.321 |
|
| 2011 |
Tamargo J, Caballero R, Delpón E. Ranolazine: an antianginal drug with antiarrhythmic properties. Expert Review of Cardiovascular Therapy. 9: 815-27. PMID 21809962 DOI: 10.1586/Erc.11.91 |
0.341 |
|
| 2011 |
Aliot E, Capucci A, Crijns HJ, Goette A, Tamargo J. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 13: 161-73. PMID 21138930 DOI: 10.1093/Europace/Euq382 |
0.324 |
|
| 2011 |
Amorós I, Jiménez-Jáimez J, Tercedor L, Barana A, Gómez R, de la Fuente MG, Dolz-Gaitón P, Alvarez M, Martínez-Espín E, Lorente JA, Melgares R, Tamargo J, Delpón E, Caballero R. Functional effects of a missense mutation in HERG associated with type 2 long QT syndrome. Heart Rhythm. 8: 463-70. PMID 21109023 DOI: 10.1016/J.Hrthm.2010.11.032 |
0.457 |
|
| 2010 |
Caballero R, Dolz-Gaitón P, Gómez R, Amorós I, Barana A, González de la Fuente M, Osuna L, Duarte J, López-Izquierdo A, Moraleda I, Gálvez E, Sánchez-Chapula JA, Tamargo J, Delpón E. Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification. Proceedings of the National Academy of Sciences of the United States of America. 107: 15631-6. PMID 20713726 DOI: 10.1073/Pnas.1004021107 |
0.526 |
|
| 2010 |
Tamargo J, Caballero R, Gómez R, Delpón E. Cardiac electrophysiological effects of nitric oxide. Cardiovascular Research. 87: 593-600. PMID 20587506 DOI: 10.1093/Cvr/Cvq214 |
0.499 |
|
| 2010 |
Caballero R, de la Fuente MG, Gómez R, Barana A, Amorós I, Dolz-Gaitón P, Osuna L, Almendral J, Atienza F, Fernández-Avilés F, Pita A, Rodríguez-Roda J, Pinto A, Tamargo J, Delpón E. In humans, chronic atrial fibrillation decreases the transient outward current and ultrarapid component of the delayed rectifier current differentially on each atria and increases the slow component of the delayed rectifier current in both. Journal of the American College of Cardiology. 55: 2346-54. PMID 20488306 DOI: 10.1016/J.Jacc.2010.02.028 |
0.474 |
|
| 2010 |
Tamargo J, Amorós I, Barana A, Caballero R, Delpón E. New investigational drugs for the management of acute heart failure syndromes. Current Medicinal Chemistry. 17: 363-90. PMID 20015042 DOI: 10.2174/092986710790192721 |
0.303 |
|
| 2010 |
Barana A, Amorós I, Caballero R, Gómez R, Osuna L, Lillo MP, Blázquez C, Guzmán M, Delpón E, Tamargo J. Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner. Cardiovascular Research. 85: 56-67. PMID 19689982 DOI: 10.1093/Cvr/Cvp284 |
0.506 |
|
| 2010 |
Amorós I, Barana A, Caballero R, Gómez R, Osuna L, Lillo MP, Tamargo J, Delpón E. Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. Journal of Molecular and Cellular Cardiology. 48: 201-10. PMID 19616555 DOI: 10.1016/J.Yjmcc.2009.07.011 |
0.521 |
|
| 2010 |
Tamargo J, Amorós I, Barana A, González M, Dolz P, Gómez R, Caballero R, Delpón E. Farmacología clínica de la ranolazina, un nuevo fármaco en el tratamiento de la angina crónica estable Revista Espanola De Cardiologia. 10: 41-54. DOI: 10.1016/S1131-3587(10)70014-5 |
0.444 |
|
| 2009 |
Gómez R, Caballero R, Barana A, Amorós I, Calvo E, López JA, Klein H, Vaquero M, Osuna L, Atienza F, Almendral J, Pinto A, Tamargo J, Delpón E. Nitric oxide increases cardiac IK1 by nitrosylation of cysteine 76 of Kir2.1 channels. Circulation Research. 105: 383-92. PMID 19608980 DOI: 10.1161/Circresaha.109.197558 |
0.502 |
|
| 2009 |
Tamargo J, Caballero R, Gómez R, Barana A, Amorós I, Delpón E. Investigational positive inotropic agents for acute heart failure. Cardiovascular & Hematological Disorders Drug Targets. 9: 193-205. PMID 19534658 DOI: 10.2174/187152909789007070 |
0.499 |
|
| 2009 |
Tamargo J, Caballero R, Gómez R, Delpón E. I(Kur)/Kv1.5 channel blockers for the treatment of atrial fibrillation. Expert Opinion On Investigational Drugs. 18: 399-416. PMID 19335273 DOI: 10.1517/13543780902762850 |
0.523 |
|
| 2009 |
Radicke S, Vaquero M, Caballero R, Gómez R, Núñez L, Tamargo J, Ravens U, Wettwer E, Delpón E. Effects of MiRP1 and DPP6 β‐subunits on the blockade induced by flecainide of KV4.3/KChIP2 channels British Journal of Pharmacology. 154: 774-786. PMID 18536731 DOI: 10.1038/Bjp.2008.134 |
0.494 |
|
| 2008 |
Gómez R, Núñez L, Vaquero M, Amorós I, Barana A, de Prada T, Macaya C, Maroto L, Rodríguez E, Caballero R, López-Farré A, Tamargo J, Delpón E. Nitric oxide inhibits Kv4.3 and human cardiac transient outward potassium current (Ito1). Cardiovascular Research. 80: 375-84. PMID 18678642 DOI: 10.1093/Cvr/Cvn205 |
0.501 |
|
| 2008 |
Marrugat J, López-López JR, Heras M, Tamargo J, Valverde M. [The HERACLES Cardiovascular Network]. Revista EspañOla De CardiologíA. 61: 66-75. PMID 18221693 DOI: 10.1157/13114959 |
0.339 |
|
| 2008 |
Marrugat J, López-López JR, Heras M, Tamargo J, Valverde M. The HERACLES Cardiovascular Network Revista Espanola De Cardiologia. 61: 66-75. DOI: 10.1016/S1885-5857(08)60070-5 |
0.34 |
|
| 2007 |
Moreno L, Frazziano G, Cogolludo A, Cobeño L, Tamargo J, Perez-Vizcaino F. Role of protein kinase Czeta and its adaptor protein p62 in voltage-gated potassium channel modulation in pulmonary arteries. Molecular Pharmacology. 72: 1301-9. PMID 17699685 DOI: 10.1124/Mol.107.037002 |
0.339 |
|
| 2007 |
Vaquero M, Caballero R, Gómez R, Núñez L, Tamargo J, Delpón E. Effects of atorvastatin and simvastatin on atrial plateau currents. Journal of Molecular and Cellular Cardiology. 42: 931-945. PMID 17466325 DOI: 10.1016/J.Yjmcc.2007.03.807 |
0.525 |
|
| 2007 |
Sanchez M, Lodi F, Vera R, Villar IC, Cogolludo A, Jimenez R, Moreno L, Romero M, Tamargo J, Perez-Vizcaino F, Duarte J. Quercetin and isorhamnetin prevent endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II in rat aorta. The Journal of Nutrition. 137: 910-5. PMID 17374653 DOI: 10.1093/Jn/137.4.910 |
0.3 |
|
| 2007 |
Tamargo J, Caballero R, Gómez R, Núñez L, Vaquero M, Delpón E. Lipid-lowering therapy with statins, a new approach to antiarrhythmic therapy. Pharmacology & Therapeutics. 114: 107-26. PMID 17287023 DOI: 10.1016/J.Pharmthera.2006.12.002 |
0.461 |
|
| 2007 |
Tamargo J, Caballero R, Núñez L, Gómez R, Vaquero M, Delpón E. Genetically engineered mice as a model for studying cardiac arrhythmias. Frontiers in Bioscience : a Journal and Virtual Library. 12: 22-38. PMID 17127281 DOI: 10.2741/2046 |
0.457 |
|
| 2007 |
Cogolludo A, Frazziano G, Briones AM, Cobeño L, Moreno L, Lodi F, Salaices M, Tamargo J, Perez-Vizcaino F. The dietary flavonoid quercetin activates BKCa currents in coronary arteries via production of H2O2. Role in vasodilatation. Cardiovascular Research. 73: 424-31. PMID 17055466 DOI: 10.1016/J.Cardiores.2006.09.008 |
0.319 |
|
| 2007 |
Tamargo J, Delpón E, Caballero R. The safety of digoxin as a pharmacological treatment of atrial fibrillation. Expert Opinion On Drug Safety. 5: 453-67. PMID 16610972 DOI: 10.1517/14740338.5.3.453 |
0.341 |
|
| 2007 |
Vaquero M, Gómez R, Núñez L, Caballero R, Delpón E, Barana A, Tamargo J. Ivabradina, un bloqueador selectivo de la corriente If. Aspectos farmacológicos y tolerabilidad Revista EspañOla De Cardiología Suplementos. 7: 32D-45D. DOI: 10.1016/S1131-3587(07)75774-6 |
0.427 |
|
| 2006 |
Cogolludo A, Frazziano G, Cobeño L, Moreno L, Lodi F, Villamor E, Tamargo J, Perez-Vizcaino F. Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries. Annals of the New York Academy of Sciences. 1091: 41-51. PMID 17341601 DOI: 10.1196/Annals.1378.053 |
0.354 |
|
| 2006 |
Tutor AS, Delpón E, Caballero R, Gómez R, Núñez L, Vaquero M, Tamargo J, Mayor F, Penela P. Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems. Molecular Biology of the Cell. 17: 4666-74. PMID 16914520 DOI: 10.1091/Mbc.E06-05-0422 |
0.454 |
|
| 2006 |
Núñez L, Vaquero M, Gómez R, Caballero R, Mateos-Cáceres P, Macaya C, Iriepa I, Gálvez E, López-Farré A, Tamargo J, Delpón E. Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism. Cardiovascular Research. 72: 80-9. PMID 16876149 DOI: 10.1016/J.Cardiores.2006.06.021 |
0.5 |
|
| 2006 |
Lodi F, Cogolludo A, Duarte J, Moreno L, Coviello A, Peral De Bruno M, Vera R, Galisteo M, Jiménez R, Tamargo J, Perez-Vizcaino F. Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats. European Journal of Pharmacology. 544: 97-103. PMID 16842772 DOI: 10.1016/J.Ejphar.2006.06.028 |
0.301 |
|
| 2006 |
Cogolludo A, Moreno L, Lodi F, Frazziano G, Cobeño L, Tamargo J, Perez-Vizcaino F. Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells: role of 5-HT2A receptors, caveolin-1, and KV1.5 channel internalization. Circulation Research. 98: 931-8. PMID 16527989 DOI: 10.1161/01.Res.0000216858.04599.E1 |
0.322 |
|
| 2006 |
Tamargo J, Caballero R, Gómez R, Núñez L, Vaquero M, Delpón E. Características farmacológicas de los ARA-II. ¿Son todos iguales? Revista Espanola De Cardiologia. 6: 10-24. DOI: 10.1016/S1131-3587(06)75306-7 |
0.42 |
|
| 2006 |
Núñez L, Caballero R, Gómez R, Vaquero M, Delpón E, Tamargo J. Mecanismo de acción de la eplerenona Revista EspañOla De Cardiología Suplementos. 6: 31B-47B. DOI: 10.1016/S1131-3587(06)75301-8 |
0.436 |
|
| 2006 |
Caballero R, Gómez R, Núñez L, Vaquero M, Tamargo J, Delpón E. Farmacología de los ácidos grasos omega-3 Revista EspañOla De Cardiología Suplementos. 6: 3-19. DOI: 10.1016/S1131-3587(06)74822-1 |
0.424 |
|
| 2006 |
Tamargo J, Caballero R, Gómez R, Núñez L, Vaquero M, Delpón E. Efectos del óxido nítrico sobre la función cardíaca Revista EspañOla De Cardiología Suplementos. 6: 3-20. DOI: 10.1016/S1131-3587(06)74816-6 |
0.427 |
|
| 2005 |
Gómez R, Núñez L, Caballero R, Vaquero M, Tamargo J, Delpón E. Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1 + minK channels. British Journal of Pharmacology. 146: 146-61. PMID 15980874 DOI: 10.1038/Sj.Bjp.0706302 |
0.526 |
|
| 2005 |
Cogolludo A, Moreno L, Lodi F, Tamargo J, Perez-Vizcaino F. Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction. Cardiovascular Research. 66: 84-93. PMID 15769451 DOI: 10.1016/J.Cardiores.2004.12.019 |
0.335 |
|
| 2005 |
Delpón E, Caballero R, Gómez R, Núñez L, Tamargo J. Angiotensin II, angiotensin II antagonists and spironolactone and their modulation of cardiac repolarization. Trends in Pharmacological Sciences. 26: 155-61. PMID 15749161 DOI: 10.1016/J.Tips.2005.01.006 |
0.52 |
|
| 2004 |
Caballero R, Gómez R, Núñez L, Moreno I, Tamargo J, Delpón E. Diltiazem inhibits hKv1.5 and Kv4.3 currents at therapeutic concentrations. Cardiovascular Research. 64: 457-66. PMID 15537499 DOI: 10.1016/J.Cardiores.2004.07.022 |
0.541 |
|
| 2004 |
Moreno L, Losada B, Cogolludo AL, Lodi F, Lugnier C, Villamor E, Moro M, Tamargo J, Pérez-Vizcaíno F. Postnatal Maturation of Phosphodiesterase 5 (PDE5) in Piglet Pulmonary Arteries: Activity, Expression, Effects of PDE5 Inhibitors, and Role of the Nitric Oxide/Cyclic GMP Pathway Pediatric Research. 56: 563-570. PMID 15295092 DOI: 10.1203/01.Pdr.0000139412.58594.D0 |
0.301 |
|
| 2004 |
Caballero R, Gómez R, Moreno I, Nuñez L, González T, Arias C, Guizy M, Valenzuela C, Tamargo J, Delpón E. Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current. Cardiovascular Research. 62: 86-95. PMID 15023555 DOI: 10.1016/J.Cardiores.2003.12.029 |
0.507 |
|
| 2004 |
Tamargo J, Caballero R, Gómez R, Valenzuela C, Delpón E. Pharmacology of cardiac potassium channels. Cardiovascular Research. 62: 9-33. PMID 15023549 DOI: 10.1016/J.Cardiores.2003.12.026 |
0.542 |
|
| 2004 |
Tamargo J, Caballero R, Delpón E. Pharmacological approaches in the treatment of atrial fibrillation. Current Medicinal Chemistry. 11: 13-28. PMID 14754423 DOI: 10.2174/0929867043456241 |
0.337 |
|
| 2004 |
Caballero R, Pourrier M, Schram G, Delpón E, Tamargo J, Nattel S. Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines. British Journal of Pharmacology. 138: 1475-84. PMID 12721103 DOI: 10.1038/Sj.Bjp.0705199 |
0.342 |
|
| 2003 |
Ibarra M, Moreno L, Vera R, Cogolludo A, Duarte J, Tamargo J, Perez-Vizcaino F. Effects of the Flavonoid Quercetin and its Methylated Metabolite Isorhamnetin in Isolated Arteries from Spontaneously Hypertensive Rats Planta Medica. 69: 995-1000. PMID 14735435 DOI: 10.1055/S-2003-45144 |
0.3 |
|
| 2003 |
Cogolludo A, Moreno L, Bosca L, Tamargo J, Perez-Vizcaino F. Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta. Circulation Research. 93: 656-63. PMID 12970114 DOI: 10.1161/01.Res.0000095245.97945.Fe |
0.376 |
|
| 2003 |
Arias C, González T, Moreno I, Caballero R, Delpón E, Tamargo J, Valenzuela C. Effects of propafenone and its main metabolite, 5-hydroxypropafenone, on HERG channels. Cardiovascular Research. 57: 660-9. PMID 12618228 DOI: 10.1016/S0008-6363(02)00726-5 |
0.329 |
|
| 2003 |
Caballero R, Moreno I, González T, Arias C, Valenzuela C, Delpón E, Tamargo J. Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels. Circulation. 107: 889-95. PMID 12591761 DOI: 10.1161/01.Cir.0000048189.58449.F7 |
0.307 |
|
| 2003 |
Moreno I, Caballero R, González T, Arias C, Valenzuela C, Iriepa I, Gálvez E, Tamargo J, Delpón E. Effects of irbesartan on cloned potassium channels involved in human cardiac repolarization. The Journal of Pharmacology and Experimental Therapeutics. 304: 862-73. PMID 12538844 DOI: 10.1124/Jpet.102.042325 |
0.36 |
|
| 2003 |
González T, Arias C, Caballero R, Moreno I, Delpón E, Tamargo J, Valenzuela C. Effects of levobupivacaine, ropivacaine and bupivacaine on HERG channels: stereoselective bupivacaine block. British Journal of Pharmacology. 137: 1269-79. PMID 12466236 DOI: 10.1038/Sj.Bjp.0704978 |
0.346 |
|
| 2002 |
Caballero R, Moreno I, González T, Valenzuela C, Tamargo J, Delpón E. Putative binding sites for benzocaine on a human cardiac cloned channel (Kv1.5). Cardiovascular Research. 56: 104-17. PMID 12237171 DOI: 10.1016/S0008-6363(02)00509-6 |
0.342 |
|
| 2002 |
Pérez-Vizcaíno F, López-López JG, Santiago R, Cogolludo A, Zaragozá-Arnáez F, Moreno L, Alonso MJ, Salaices M, Tamargo J. Postnatal maturation in nitric oxide-induced pulmonary artery relaxation involving cyclooxygenase-1 activity. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L839-48. PMID 12225961 DOI: 10.1152/Ajplung.00293.2001 |
0.3 |
|
| 2001 |
Longobardo M, González T, Caballero R, Delpón E, Tamargo J, Valenzuela C. Bupivacaine effects on hKv1.5 channels are dependent on extracellular pH. British Journal of Pharmacology. 134: 359-369. PMID 11564654 DOI: 10.1038/Sj.Bjp.0704251 |
0.319 |
|
| 2001 |
Duarte J, Jiménez R, Villar IC, Pérez-Vizcaíno F, Jiménez J, Tamargo J. Vasorelaxant effects of the bioflavonoid chrysin in isolated rat aorta. Planta Medica. 67: 567-569. PMID 11509985 DOI: 10.1055/S-2001-16492 |
0.313 |
|
| 2001 |
Duarte J, Pérez-Palencia R, Vargas F, Ocete MA, Pérez-Vizcaino F, Zarzuelo A, Tamargo J. Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. British Journal of Pharmacology. 133: 117-24. PMID 11325801 DOI: 10.1038/Sj.Bjp.0704064 |
0.305 |
|
| 2001 |
Caballero R, Delpón E, Valenzuela C, Longobardo M, González T, Tamargo J. Direct Effects of Candesartan and Eprosartan on Human Cloned Potassium Channels Involved in Cardiac Repolarization Molecular Pharmacology. 59: 825-836. PMID 11259627 DOI: 10.1124/Mol.59.4.825 |
0.36 |
|
| 2001 |
Cogolludo AL, Pérez‐Vizcaíno F, Zaragozá‐Arnáez F, Ibarra M, López‐López G, López‐Miranda V, Tamargo J. Mechanisms involved in SNP-induced relaxation and [Ca2+]i reduction in piglet pulmonary and systemic arteries British Journal of Pharmacology. 132: 959-967. PMID 11181438 DOI: 10.1038/Sj.Bjp.0703894 |
0.318 |
|
| 2001 |
González T, Longobardo M, Caballero R, Delpón E, Sinisterra JV, Tamargo J, Valenzuela C. Stereoselective effects of the enantiomers of a new local anaesthetic, IQB-9302, on a human cardiac potassium channel (Kv1.5). British Journal of Pharmacology. 132: 385-392. PMID 11159686 DOI: 10.1038/Sj.Bjp.0703844 |
0.33 |
|
| 2001 |
Juan D, PÉrez-VizcaÍno F, JimÉnez J, Tamargo J, Zarzuelo A. Flavonoids and cardiovascular diseases Studies in Natural Products Chemistry. 25: 565-605. DOI: 10.1016/S1572-5995(01)80018-1 |
0.32 |
|
| 2000 |
Tamargo J. Drug-induced torsade de pointes: from molecular biology to bedside. Japanese Journal of Pharmacology. 83: 1-19. PMID 10887935 DOI: 10.1254/Jjp.83.1 |
0.364 |
|
| 2000 |
Longobardo M, González T, Navarro-Polanco R, Caballero R, Delpón E, Tamargo J, Snyders DJ, Tamkun MM, Valenzuela C. Effects of a quaternary bupivacaine derivative on delayed rectifier K(+) currents. British Journal of Pharmacology. 130: 391-401. PMID 10807678 DOI: 10.1038/Sj.Bjp.0703334 |
0.336 |
|
| 2000 |
Caballero R, Delpón E, Valenzuela C, Longobardo M, Tamargo J. Losartan and Its Metabolite E3174 Modify Cardiac Delayed Rectifier K+ Currents Circulation. 101: 1199-1205. PMID 10715269 DOI: 10.1161/01.Cir.101.10.1199 |
0.328 |
|
| 1999 |
Pérez-Vizcaíno F, Cogolludo AL, Zaragozá-Arnáez F, Fajardo S, Ibarra M, López-López JG, Tamargo J. Vasodilator effects of sodium nitroprusside, levcromakalim and their combination in isolated rat aorta. British Journal of Pharmacology. 128: 1419-1426. PMID 10602320 DOI: 10.1038/Sj.Bjp.0702924 |
0.337 |
|
| 1999 |
Delpón E, Valenzuela C, Tamargo J. Blockade of Cardiac Potassium and Other Channels by Antihistamines Drug Safety. 21: 11-18. PMID 10597864 DOI: 10.2165/00002018-199921001-00003 |
0.394 |
|
| 1999 |
Caballero R, Valenzuela C, Longobardo M, Tamargo J, Delpón E. Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac Kv1.5 channels British Journal of Pharmacology. 128: 1071-1081. PMID 10556945 DOI: 10.1038/Sj.Bjp.0702890 |
0.318 |
|
| 1999 |
Delpón E, Caballero R, Valenzuela C, Longobardo M, Snyders D, Tamargo J. Benzocaine enhances and inhibits the K+ current through a human cardiac cloned channel (Kv1.5). Cardiovascular Research. 42: 510-20. PMID 10533586 DOI: 10.1016/S0008-6363(99)00043-7 |
0.361 |
|
| 1999 |
Jiménez R, Andriambeloson E, Duarte J, Andriantsitohaina R, Jiménez J, Pérez-Vizcaino F, Zarzuelo A, Tamargo J. Involvement of thromboxane A2 in the endothelium‐dependent contractions induced by myricetin in rat isolated aorta British Journal of Pharmacology. 127: 1539-1544. PMID 10455307 DOI: 10.1038/Sj.Bjp.0702694 |
0.329 |
|
| 1999 |
Franqueza L, Valenzuela C, Eck J, Tamkun MM, Tamargo J, Snyders DJ. Functional expression of an inactivating potassium channel (Kv4.3) in a mammalian cell line. Cardiovascular Research. 41: 212-9. PMID 10325968 DOI: 10.1016/S0008-6363(98)00220-X |
0.302 |
|
| 1999 |
Cogolludo AL, Pérez-Vizcaíno F, Fajardo S, Ibarra M, Tamargo J. Effects of nicorandil as compared to mixtures of sodium nitroprusside and levcromakalim in isolated rat aorta British Journal of Pharmacology. 126: 1025-1033. PMID 10193784 DOI: 10.1038/Sj.Bjp.0702375 |
0.337 |
|
| 1999 |
Pérez-Vizcaíno F, Cogolludo A, Tamargo J. Modulation of arterial Na+-K+-ATPase-induced [Ca2+]i reduction and relaxation by norepinephrine, ET-1, and PMA. The American Journal of Physiology. 276: H651-7. PMID 9950867 DOI: 10.1152/Ajpheart.1999.276.2.H651 |
0.324 |
|
| 1999 |
Duarte J, Lugnier C, Torres AI, Pérez-Vizcaino F, Zarzuelo A, Tamargo J. Effects of visnagin on cyclic nucleotide phosphodiesterases and their role in its inhibitory effects on vascular smooth muscle contraction. General Pharmacology. 32: 71-4. PMID 9888257 DOI: 10.1016/S0306-3623(98)00083-4 |
0.309 |
|
| 1998 |
Franqueza L, Valenzuela C, Delpón E, Longobardo M, Caballero R, Tamargo J. Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels. British Journal of Pharmacology. 125: 969-978. PMID 9846634 DOI: 10.1038/Sj.Bjp.0702129 |
0.332 |
|
| 1998 |
Perez-Vizcaino F, Fernandez C, Pozo BFD, Cogolludo A, Zaragoza F, Tamargo J. Vasoconstrictor and vasodilator effects of disopyramide on isolated rat vascular smooth muscle. Journal of Cardiovascular Pharmacology. 32: 745-752. PMID 9821848 DOI: 10.1097/00005344-199811000-00010 |
0.363 |
|
| 1998 |
Longobardo M, Delpón E, Caballero R, Tamargo J, Valenzuela C. Structural Determinants of Potency and Stereoselective Block of hKv1.5 Channels Induced by Local Anesthetics Molecular Pharmacology. 54: 162-169. PMID 9658202 DOI: 10.1124/Mol.54.1.162 |
0.304 |
|
| 1998 |
Pérez-Vizcaíno F, Cogolludo AL, Villamor E, Tamargo J. Role of K+ channel opening and stimulation of cyclic GMP in the vasorelaxant effects of nicorandil in isolated piglet pulmonary and mesenteric arteries: relative efficacy and interactions between both pathways British Journal of Pharmacology. 123: 847-854. PMID 9535012 DOI: 10.1038/Sj.Bjp.0701693 |
0.362 |
|
| 1998 |
Villamor E, Perez-Vizcaino F, Cogolludo A, Tamargo J, Moro M. Relaxant and Intracellular Calcium Lowering Effects of Sodium Nitroprusside in Piglet Pulmonary Arteries Stimulated by the Thromboxane A2 Mimetic U46619 and Noradrenaline ♦ 357 Pediatric Research. 43: 63-63. DOI: 10.1203/00006450-199804001-00378 |
0.316 |
|
| 1997 |
Duarte J, Ocete MA, Pérez-Vizcaino F, Zarzuelo A, Tamargo J. Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase European Journal of Pharmacology. 338: 25-33. PMID 9408000 DOI: 10.1016/S0014-2999(97)01311-3 |
0.309 |
|
| 1997 |
Caballero R, Delpón E, Valenzuela C, Longobardo M, Franqueza L, Tamargo J. Effect of descarboethoxyloratadine, the major metabolite of loratadine, on the human cardiac potassium channel Kv1.5 British Journal of Pharmacology. 122: 796-798. PMID 9384491 DOI: 10.1038/Sj.Bjp.0701468 |
0.375 |
|
| 1997 |
Pozo BFd, Pérez-Vizcaı́no F, Fernández C, Zaragozá F, Tamargo J. Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle. General Pharmacology-the Vascular System. 29: 539-543. PMID 9352299 DOI: 10.1016/S0306-3623(96)00517-4 |
0.386 |
|
| 1997 |
Delpón E, Valenzuela C, Gay P, Franqueza L, Snyders DJ, Tamargo J. Block of human cardiac Kv1.5 channels by loratadine: voltage-, time- and use-dependent block at concentrations above therapeutic levels. Cardiovascular Research. 35: 341-50. PMID 9349397 DOI: 10.1016/S0008-6363(97)00121-1 |
0.358 |
|
| 1997 |
Pérez-Vizcaíno F, Villamor E, Duarte J, Tamargo J. Involvement of protein kinase C in reduced relaxant responses to the NO/cyclic GMP pathway in piglet pulmonary arteries contracted by the thromboxane A2‐mimetic U46619 British Journal of Pharmacology. 121: 1323-1333. PMID 9257910 DOI: 10.1038/Sj.Bjp.0701257 |
0.329 |
|
| 1997 |
Duarte J, Vallejo I, Pérez-Vizcaino F, Jiménez R, Zarzuelo A, Tamargo J. Effects of visnadine on rat isolated vascular smooth muscles. Planta Medica. 63: 233-236. PMID 9225605 DOI: 10.1055/S-2006-957660 |
0.36 |
|
| 1997 |
Pérez O, Valenzuela C, Delpón E, Tamargo J. Electrophysiological effects of CI-980, a tubulin binding agent, on guinea-pig papillary muscles British Journal of Pharmacology. 120: 187-192. PMID 9117108 DOI: 10.1038/Sj.Bjp.0700878 |
0.321 |
|
| 1997 |
Valenzuela C, Delpón E, Franqueza L, Gay P, Snyders DJ, Tamargo J. Effects of ropivacaine on a potassium channel (hKv1.5) cloned from human ventricle. Anesthesiology. 86: 718-28. PMID 9066339 DOI: 10.1097/00000542-199703000-00025 |
0.375 |
|
| 1997 |
Villamor E, Pérez-Vizcaino F, Cogolludo AL, Del Pozo BF, Moro M, Tamargo J. Relaxant effects of nicorandil (a NO donor and potassium channel opener) in isolated piglet pulmonary arteries ♦ 338 Pediatric Research. 41: 59-59. DOI: 10.1203/00006450-199704001-00358 |
0.314 |
|
| 1996 |
Delpón E, Valenzuela C, Pérez O, Franqueza L, Gay P, Snyders DJ, Tamargo J. Mechanisms of block of a human cloned potassium channel by the enantiomers of a new bradycardic agent: S-16257-2 and S-16260-2. British Journal of Pharmacology. 117: 1293-301. PMID 8882628 DOI: 10.1111/J.1476-5381.1996.Tb16728.X |
0.315 |
|
| 1996 |
del Pozo BF, Pérez-Vizcaíno F, Villamor E, Zaragozá F, Tamargo J. Stereoselective effects of the enantiomers, quinidine and quinine, on depolarization- and agonist-mediated responses in rat isolated aorta. British Journal of Pharmacology. 117: 105-10. PMID 8825350 DOI: 10.1111/J.1476-5381.1996.Tb15161.X |
0.331 |
|
| 1996 |
Valenzuela C, Delpón E, Franqueza L, Gay P, Pérez O, Tamargo J, Snyders DJ. Class III antiarrhythmic effects of zatebradine. Time-, state-, use-, and voltage-dependent block of hKv1.5 channels. Circulation. 94: 562-70. PMID 8759103 DOI: 10.1161/01.Cir.94.3.562 |
0.358 |
|
| 1996 |
Tamargo J, Pérez O, Delpón E, Pérez-Vizcaíno F, García-Rafanell J, Gómez L, Cavalcanti F. Pharmacology of UR-8225, a New Potassium Channel Opener Cardiovascular Drug Reviews. 14: 256-271. DOI: 10.1111/J.1527-3466.1996.Tb00230.X |
0.31 |
|
| 1995 |
Pérez O, Franqueza L, Carron R, Valenzuela C, Delpon E, Tamargo J. Effects of the two enantiomers, S-16257-2 and S-16260-2, of a new bradycardic agent on guinea-pig isolated cardiac preparations. British Journal of Pharmacology. 115: 787-794. PMID 8548178 DOI: 10.1111/J.1476-5381.1995.Tb15002.X |
0.337 |
|
| 1995 |
Valenzuela C, Delpón E, Tamkun MM, Tamargo J, Snyders DJ. Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers. Biophysical Journal. 69: 418-27. PMID 8527655 DOI: 10.1016/S0006-3495(95)79914-3 |
0.358 |
|
| 1995 |
Pérez-Vizcaíno F, Fernández del Pozo B, Zaragozá F, Tamargo J. Voltage- and time-dependent inhibitory effects on rat aortic and porcine coronary artery contraction induced by propafenone and quinidine. British Journal of Pharmacology. 113: 1281-8. PMID 7889284 DOI: 10.1111/J.1476-5381.1994.Tb17137.X |
0.373 |
|
| 1995 |
Delpón E, Valenzuela C, Pérez O, Casis O, Tamargo J. Propafenone Preferentially Blocks the Rapidly Activating Component of Delayed Rectifier K+ Current in Guinea Pig Ventricular Myocytes : Voltage-Independent and Time-Dependent Block of the Slowly Activating Component Circulation Research. 76: 223-235. PMID 7834833 DOI: 10.1161/01.Res.76.2.223 |
0.316 |
|
| 1995 |
Valenzuela C, Snyders DJ, Bennett PB, Tamargo J, Hondeghem LM. Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes. Circulation. 92: 3014-24. PMID 7586272 DOI: 10.1161/01.Cir.92.10.3014 |
0.348 |
|
| 1995 |
PÉrez O, Franqueza L, CarrÓn R, Valenzuela C, DelpÓn E, Tamargo J. Electromechanical effects of zatebradine on isolated guinea pig cardiac preparations. Journal of Cardiovascular Pharmacology. 26: 46-54. PMID 7564364 DOI: 10.1097/00005344-199507000-00008 |
0.35 |
|
| 1995 |
Villamor E, Pérez-VizcaÃno F, Ruiz T, Leza JC, Moro M, Tamargo J. Group B Streptococcus and E. coli LPS-induced NO-dependent hyporesponsiveness to noradrenaline in isolated intrapulmonary arteries of neonatal piglets. British Journal of Pharmacology. 115: 261-6. PMID 7545518 DOI: 10.1111/J.1476-5381.1995.Tb15872.X |
0.306 |
|
| 1995 |
Tamargo J, Pérez O, Delpón E, García-Rafanell J, Gómez L, Cavalcanti F. Cardiovascular effects of the novel potassium channel opener UR-8225. Journal of Cardiovascular Pharmacology. 26: 295-305. PMID 7475055 DOI: 10.1097/00005344-199508000-00016 |
0.369 |
|
| 1994 |
Valenzuela C, Sánchez-Chapula J, Delpón E, Elizalde A, Pérez O, Tamargo J. Imipramine blocks rapidly activating and delays slowly activating K+ current activation in guinea pig ventricular myocytes. Circulation Research. 74: 687-699. PMID 8137505 DOI: 10.1161/01.Res.74.4.687 |
0.349 |
|
| 1994 |
Pérez O, Valenzuela C, Delpón E, Tamargo J. Class I and III antiarrhythmic actions of prazosin in guinea-pig papillary muscles. British Journal of Pharmacology. 111: 717-722. PMID 8019750 DOI: 10.1111/J.1476-5381.1994.Tb14796.X |
0.358 |
|
| 1994 |
Valenzuela C, Pérez O, Delpón E, Tamargo J. Effects of lisinopril on cardiac contractility and ionic currents. General Pharmacology-the Vascular System. 25: 825-832. PMID 7835625 DOI: 10.1016/0306-3623(94)90083-3 |
0.395 |
|
| 1994 |
Duarte J, Pérez-Vizcaíno F, Zarzuelo A, Jiménez J, Tamargo J. Inhibitory effects of quercetin and staurosporine on phasic contractions in rat vascular smooth muscle European Journal of Pharmacology. 262: 149-156. PMID 7813566 DOI: 10.1016/0014-2999(94)90038-8 |
0.322 |
|
| 1993 |
Pérez-Vizcaíno F, Carrón R, Delpón E, Duarte J, Tamargo J. Effects of (S)-nafenodone on 45Ca2+ fluxes and contractions in rat isolated vascular smooth muscle European Journal of Pharmacology. 232: 105-111. PMID 8458390 DOI: 10.1016/0014-2999(93)90734-Y |
0.32 |
|
| 1993 |
Delgado C, Tamargo J, Henzel D, Lorente P. Effects of propafenone on calcium current in guinea-pig ventricular myocytes. British Journal of Pharmacology. 108: 721-727. PMID 8385535 DOI: 10.1111/J.1476-5381.1993.Tb12868.X |
0.374 |
|
| 1993 |
Duarte J, Pérez O, Zarzuelo A, Jiménez J, Pérez-Vizcaíno F, Tamargo J. Effects of oleuropeoside in isolated guinea-pig atria. Planta Medica. 59: 318-322. PMID 8372147 DOI: 10.1055/S-2006-959690 |
0.339 |
|
| 1993 |
Perez-Vizcaino F, Casis O, Rodriguez R, Gomez LA, Rafanell JG, Tamargo J. Effects of the novel potassium channel opener, UR‐8225, on contractile responses in rat isolated smooth muscle British Journal of Pharmacology. 110: 1165-1171. PMID 8298804 DOI: 10.1111/J.1476-5381.1993.Tb13936.X |
0.36 |
|
| 1993 |
Duarte J, Vizcaíno FP, Utrilla P, Jiménez J, Tamargo J, Zarzuelo A. Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships General Pharmacology-the Vascular System. 24: 857-862. PMID 8224739 DOI: 10.1016/0306-3623(93)90159-U |
0.312 |
|
| 1993 |
Duarte J, Pérez-Vizcaíno F, Zarzuelo A, Jiménez J, Tamargo J. Vasodilator effects of quercetin in isolated rat vascular smooth muscle European Journal of Pharmacology. 239: 1-7. PMID 8223884 DOI: 10.1016/0014-2999(93)90968-N |
0.328 |
|
| 1993 |
Duarte J, Pérez-Vizcaíno F, Zarzuelo A, Jiménez J, Tamargo J. Aminophylline preferentially inhibits chloroethylclonidine-insensitive α-adrenoceptor-mediated contractions in rat aorta General Pharmacology-the Vascular System. 24: 1359-1364. PMID 7906660 DOI: 10.1016/0306-3623(93)90419-X |
0.312 |
|
| 1993 |
Valenzuela C, Pérez O, Casis O, Duarte J, Pérez‐Vizcaino F, Delpón E, Tamargo J. Effects of lisinopril on electromechanical properties and membrane currents in guinea-pig cardiac preparations. British Journal of Pharmacology. 109: 873-879. PMID 7689408 DOI: 10.1111/J.1476-5381.1993.Tb13656.X |
0.379 |
|
| 1993 |
Delpón E, Valenzuela C, Pérez O, Tamargo J. Electrophysiological effects of the combination of imipramine and desipramine in guinea pig papillary muscles Journal of Cardiovascular Pharmacology. 21: 13-20. PMID 7678668 DOI: 10.1097/00005344-199301000-00003 |
0.324 |
|
| 1993 |
Pérez-vizcaíno F, Tamargo J, Hof RP, Ruegg UT. Vascular selectivity of seven prototype calcium antagonists: a study at the single cell level. Journal of Cardiovascular Pharmacology. 22: 768-775. PMID 7506331 DOI: 10.1097/00005344-199311000-00015 |
0.352 |
|
| 1993 |
Tamargo J, Valenzuela C, Delpón E. New insights into the pharmacology of sodium channel blockers. European Heart Journal. 2-13. PMID 1335869 DOI: 10.1093/Eurheartj/13.Suppl_F.2 |
0.323 |
|
| 1992 |
Tejerina T, Cauvin C, Tamargo J. Effects of oxodipine on isolated rabbit aorta and mesenteric resistance vessels. European Journal of Pharmacology. 219: 279-284. PMID 1425952 DOI: 10.1016/0014-2999(92)90306-O |
0.312 |
|
| 1992 |
Delpón E, Valenzuela C, Pérez O, Tamargo J. Electrophysiological effects of CRE-1087 in guinea-pig ventricular muscles. British Journal of Pharmacology. 107: 515-520. PMID 1422597 DOI: 10.1111/J.1476-5381.1992.Tb12776.X |
0.338 |
|
| 1992 |
Duarte J, Pérez-Vizcaino F, Jimenez J, Zarzuelo A, Tamargo J. Effects of aminophylline on contractions and 45Ca uptake in isolated rat vascular smooth muscle General Pharmacology-the Vascular System. 23: 601-606. PMID 1397967 DOI: 10.1016/0306-3623(92)90134-6 |
0.338 |
|
| 1992 |
Delpón E, Tamargo J, Sánchez‐Chapula J. Effects of imipramine on the transient outward current in rabbit atrial single cells. British Journal of Pharmacology. 106: 464-469. PMID 1382783 DOI: 10.1111/J.1476-5381.1992.Tb14357.X |
0.374 |
|
| 1991 |
Delpon E, Valenzuela C, Carron R, Perez-Vizcaino F, Tamargo J. Tonic and frequency-dependent \(\mathop {\text{V}}\limits^{\text{.}} _{{\text{max}}} \) block induced by (S)-nafenodone, a new antidepressant drug, in guinea-pig papillary muscles Naunyn-Schmiedebergs Archives of Pharmacology. 343: 638-644. PMID 1944605 DOI: 10.1007/Bf00184296 |
0.316 |
|
| 1991 |
Delpón E, Valenzuela C, Tamargo J. Electrophysiological effects of the combination of mexiletine and flecainide in guinea-pig ventricular fibres. British Journal of Pharmacology. 103: 1411-1416. PMID 1909200 DOI: 10.1111/J.1476-5381.1991.Tb09803.X |
0.36 |
|
| 1991 |
Pérez-Vizcaino F, Carrón R, Delpón E, Tamargo J. Effects of (S)-nafenodone, a new antidepressant, in isolated guinea-pig atrial and ventricular muscle fibres. European Journal of Pharmacology. 199: 43-50. PMID 1893926 DOI: 10.1016/0014-2999(91)90635-4 |
0.328 |
|
| 1991 |
Carrón R, Pérez-Vizcaino F, Delpón E, Tamargo J. Effects of propafenone on 45Ca movements and contractile responses in vascular smooth muscle. British Journal of Pharmacology. 103: 1453-7. PMID 1884101 DOI: 10.1111/J.1476-5381.1989.Tb11959.X |
0.331 |
|
| 1991 |
Pérez‐Vizcaino F, Duarte J, Tamargo J. Effects of flecainide on isolated vascular smooth muscles of rat. British Journal of Pharmacology. 104: 726-730. PMID 1797332 DOI: 10.1111/J.1476-5381.1991.Tb12495.X |
0.346 |
|
| 1991 |
Delpón E, Tamargo J, Sánchez-Chapula J. Further characterization of the effects of imipramine on plateau membrane currents in guinea-pig ventricular myocytes. Naunyn-Schmiedebergs Archives of Pharmacology. 344: 645-652. PMID 1775197 DOI: 10.1007/Bf00174748 |
0.341 |
|
| 1991 |
Ubeda A, Tejerina T, Tamargo J, Villar A. Effects of khellin on contractile responses and 45Ca2+ movements in rat isolated aorta. Journal of Pharmacy and Pharmacology. 43: 46-48. PMID 1676059 DOI: 10.1111/J.2042-7158.1991.Tb05447.X |
0.318 |
|
| 1990 |
Diez J, Delpón E, Tamargo J. Effects of platelet activating factor on contractile force and 45Ca fluxes in guinea-pig isolated atria. British Journal of Pharmacology. 100: 305-311. PMID 2379035 DOI: 10.1111/J.1476-5381.1990.Tb15800.X |
0.346 |
|
| 1990 |
Delpón E, Valenzuela C, Tamargo J. Tonic and frequency-dependent Vmax block induced by imipramine in guinea pig ventricular muscle fibers Journal of Cardiovascular Pharmacology. 15: 414-420. PMID 1691365 DOI: 10.1097/00005344-199003000-00011 |
0.335 |
|
| 1989 |
Delpón E, Valenzuela C, Tamargo J. Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle. British Journal of Pharmacology. 96: 970-976. PMID 2743087 DOI: 10.1111/J.1476-5381.1989.Tb11909.X |
0.326 |
|
| 1989 |
Valenzuela C, Delpón E, Tamargo J. Electrophysiologic interactions between mexiletine and propafenone in guinea pig papillary muscles. Journal of Cardiovascular Pharmacology. 14: 351-357. PMID 2476612 DOI: 10.1097/00005344-198909000-00001 |
0.349 |
|
| 1988 |
Tejerina T, Sesin J, Delgado C, Tamargo J. Effect of milrinone on contractility and 45Ca movements in the isolated rabbit aorta. European Journal of Pharmacology. 148: 239-246. PMID 3378573 DOI: 10.1016/0014-2999(88)90569-9 |
0.32 |
|
| 1988 |
Martin I, Alfaro MJ, Tamargo J. A comparison of the effects of oxodipine and nifedipine on rat vas deferens Journal of Pharmacy and Pharmacology. 40: 657-659. PMID 2907039 DOI: 10.1111/J.2042-7158.1988.Tb05332.X |
0.322 |
|
| 1988 |
Valenzuela C, Delpón E, Tamargo J. Tonic and phasic Vmax block induced by 5-hydroxypropafenone in guinea pig ventricular muscles. Journal of Cardiovascular Pharmacology. 12: 423-431. PMID 2465442 DOI: 10.1097/00005344-198810000-00007 |
0.351 |
|
| 1987 |
Delgado C, Tamargo J, Tejerina T, Valenzuela C. Effects of 5-hydroxy-propafenone in guinea-pig atrial fibres British Journal of Pharmacology. 90: 575-582. PMID 2882804 DOI: 10.1111/J.1476-5381.1987.Tb11208.X |
0.33 |
|
| 1986 |
Delgado C, Manzanares J, Tamargo J, Valenzuela C. Electrophysiological effects of amoxapine in untreated and in amoxapine-pretreated rat atria. British Journal of Pharmacology. 87: 317-325. PMID 3955303 DOI: 10.1111/J.1476-5381.1986.Tb10820.X |
0.35 |
|
| 1986 |
Barrigón S, Tamargo J. The effect of oxytocin on contractile responses and 45Ca movements in rat isolated aortic strips British Journal of Pharmacology. 87: 763-770. PMID 3708209 DOI: 10.1111/J.1476-5381.1986.Tb14595.X |
0.313 |
|
| 1985 |
Tamargo J, Delgado C. Electrophysiological effects of propafenone on isolated guinea-pig ventricular muscle and sheep purkinje fibres European Journal of Pharmacology. 118: 331-340. PMID 4085559 DOI: 10.1016/0014-2999(85)90144-X |
0.316 |
|
| 1985 |
Delgado C, Tamargo J, Tejerina T. Electrophysiological effects of propafenone in untreated and propafenone-pretreated guinea-pig atrial and ventricular muscle fibres British Journal of Pharmacology. 86: 765-775. PMID 4075015 DOI: 10.1111/J.1476-5381.1985.Tb11098.X |
0.32 |
|
| 1985 |
Barrigón S, Diez JJ, Tamargo J, Tejerina MT. Effects of pincainide on contractile responses and 45Ca movements in rat isolated vascular smooth muscle European Journal of Pharmacology. 111: 227-233. PMID 4018127 DOI: 10.1016/0014-2999(85)90760-5 |
0.336 |
|
| 1985 |
Tamargo J, Tejerina T, Delgado C, Barrigon S. Electrophysiological effects of platelet-activating factor (PAF-acether) in guinea-pig papillary muscles. European Journal of Pharmacology. 109: 219-227. PMID 3996472 DOI: 10.1016/0014-2999(85)90423-6 |
0.328 |
|
| 1985 |
Diez J, Tamargo J, Valenzuela C. Negative inotropic effect of somatostatin in guinea-pig atrial fibres. British Journal of Pharmacology. 86: 547-555. PMID 2866001 DOI: 10.1111/J.1476-5381.1985.Tb08930.X |
0.355 |
|
| 1985 |
Isenberg G, Tamargo J. Effect of imipramine on calcium and potassium currents in isolated bovine ventricular myocytes. European Journal of Pharmacology. 108: 121-131. PMID 2579831 DOI: 10.1016/0014-2999(85)90716-2 |
0.332 |
|
| 1984 |
Barrigon S, Tejerina T, Delgado C, Tamargo J. Effects of chlorbutol on 45 Ca movements and contractile responses of rat aorta and its relevance to the actions of Syntocinon Journal of Pharmacy and Pharmacology. 36: 521-526. PMID 6148394 DOI: 10.1111/J.2042-7158.1984.Tb04443.X |
0.325 |
|
| 1983 |
Manzanares J, Tamargo J. Electrophysiological effects of imipramine in non-treated and in imipramine-pretreated rat atrial fibres British Journal of Pharmacology. 79: 167-175. PMID 6871541 DOI: 10.1111/J.1476-5381.1983.Tb10509.X |
0.346 |
|
| 1983 |
Barrigon S, Delgado C, Tejerina T, Tamargo J. Effects of bunaphtine on 45Ca movements in rat aortic smooth muscle. Cellular and Molecular Life Sciences. 39: 761-763. PMID 6861966 DOI: 10.1007/Bf01990313 |
0.31 |
|
| 1982 |
Tamargo J, De Miguel B, Tejerina MT. A comparison of josamycin with macrolides and related antibiotics on isolated rat atria. European Journal of Pharmacology. 80: 285-93. PMID 7106186 DOI: 10.1016/0014-2999(82)90073-5 |
0.344 |
|
| 1982 |
Barrigon S, De Miguel B, Tamargo J, Tejerina T. The mechanism of the positive inotropic action of ketamine on isolated atria of the rat. British Journal of Pharmacology. 76: 85-93. PMID 7082908 DOI: 10.1111/J.1476-5381.1982.Tb09193.X |
0.335 |
|
| 1980 |
Rodriguez S, Tamargo J. Electrophysiological effects of imipramine on bovine ventricular muscle and Purkinje fibres. British Journal of Pharmacology. 70: 15-23. PMID 7426828 DOI: 10.1111/J.1476-5381.1980.Tb10899.X |
0.313 |
|
| 1980 |
Tamargo J. Electrophysiological effects of bunaphtine on isolated rat atria. European Journal of Pharmacology. 62: 81-88. PMID 7371723 DOI: 10.1016/0014-2999(80)90483-5 |
0.309 |
|
| 1979 |
Tamargo J, Rodriguez S. Electrophysiological actions of chlorimipramine on guinea-pig ventricular fibres. Cellular and Molecular Life Sciences. 35: 366-367. PMID 446618 DOI: 10.1007/Bf01964356 |
0.347 |
|
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