Panos Zanos - Publications

Affiliations: 
2014- University of Maryland School of Medicine, Baltimore, MD, United States 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zanos P, Highland JN, Liu X, Troppoli TA, Georgiou P, Lovett J, Morris PJ, Stewart BW, Thomas CJ, Thompson SM, Moaddel R, Gould TD. (R)-ketamine exerts antidepressant actions partly via conversion to (2R,6R)-hydroxynorketamine, while causing adverse effects at sub-anesthetic doses. British Journal of Pharmacology. PMID 30941749 DOI: 10.1111/bph.14683  1
2019 Highland JN, Zanos P, Georgiou P, Gould TD. Group II metabotropic glutamate receptor blockade promotes stress resilience in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30939596 DOI: 10.1038/s41386-019-0380-1  1
2019 Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA, Gould TD. ()-hydroxynorketamine exerts mGlu receptor-dependent antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867285 DOI: 10.1073/pnas.1819540116  1
2019 Georgiou P, Zanos P, Jenne CE, Gould TD. Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation. Frontiers in Psychiatry. 10: 81. PMID 30863326 DOI: 10.3389/fpsyt.2019.00081  1
2019 Rao X, Asico LD, Zanos P, Mahabeleshwar GH, Singh Gangwar R, Xia C, Duan L, Cisse YM, Rengasamy P, Jose PA, Gould TD, Nelson R, Biswal S, Chen LC, Zhong J, et al. Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30812033 DOI: 10.1093/toxsci/kfz025  1
2019 Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/pnas.1816071116  1
2018 Zanos P, Keyworth H, Georgiou P, Kitchen I, Zimmer A, Bailey A. Chronic nicotine administration restores brain region specific up-regulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia. The European Journal of Neuroscience. PMID 30218618 DOI: 10.1111/ejn.14155  1
2018 Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660. PMID 29945898 DOI: 10.1124/pr.117.015198  1
2018 Rae M, Zanos P, Georgiou P, Chivers P, Bailey A, Camarini R. Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice. Neuropharmacology. PMID 29908241 DOI: 10.1016/j.neuropharm.2018.06.013  1
2018 Brown PL, Zanos P, Wang L, Elmer GI, Gould TD, Shepard PD. Isoflurane but not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression? The International Journal of Neuropsychopharmacology. PMID 29554264 DOI: 10.1093/ijnp/pyy029  1
2018 Zanos P, Thompson SM, Duman RS, Zarate CA, Gould TD. Convergent Mechanisms Underlying Rapid Antidepressant Action. Cns Drugs. PMID 29516301 DOI: 10.1007/s40263-018-0492-x  1
2018 García-Carmona JA, Georgiou P, Zanos P, Bailey A, Laorden ML. Methamphetamine withdrawal induces activation of CRF neurons in the brain stress system in parallel with an increased activity of cardiac sympathetic pathways. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 29383398 DOI: 10.1007/s00210-018-1470-z  1
2018 Zanos P, Gould TD. Intracellular Signaling Pathways Involved in (S)- and (R)-Ketamine Antidepressant Actions. Biological Psychiatry. 83: 2-4. PMID 29173705 DOI: 10.1016/j.biopsych.2017.10.026  1
2017 Keyworth H, Georgiou P, Zanos P, Rueda AV, Chen Y, Kitchen I, Camarini R, Cropley M, Bailey A. Wheel running during chronic nicotine exposure is protective against mecamylamine-precipitated withdrawal and up-regulates hippocampal α7 nACh receptors in mice. British Journal of Pharmacology. PMID 29266170 DOI: 10.1111/bph.14068  1
2017 Morris PJ, Moaddel R, Zanos P, Moore CE, Gould TD, Zarate CA, Thomas CJ. Correction to "Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites". Organic Letters. PMID 28933164 DOI: 10.1021/acs.orglett.7b02839  1
2017 Morris PJ, Moaddel R, Zanos P, Moore CE, Gould T, Zarate CA, Thomas CJ. Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites. Organic Letters. PMID 28829612 DOI: 10.1021/acs.orglett.7b02177  0.52
2017 Georgiou P, Zanos P, Bhat S, Tracy JK, Merchenthaler IJ, McCarthy MM, Gould TD. Dopamine and Stress System Modulation of Sex Differences in Decision Making. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28741626 DOI: 10.1038/npp.2017.161  1
2017 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KSS, Fang Y, Huang XP, Mayo CL, Albuquerque EX, et al. Zanos et al. reply. Nature. 546: E4-E5. PMID 28640272 DOI: 10.1038/nature22085  1
2017 Zanos P, Georgiou P, Weber C, Robinson F, Kouimtsidis C, Niforooshan R, Bailey A. Oxytocin and opioid addiction revisited: Old drug, new applications. British Journal of Pharmacology. PMID 28378414 DOI: 10.1111/bph.13757  1
2017 Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM. A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice. Eneuro. 4. PMID 28275719 DOI: 10.1523/ENEURO.0285-16.2017  1
2017 Martynhak BJ, Hogben AL, Zanos P, Georgiou P, Andreatini R, Kitchen I, Archer SN, von Schantz M, Bailey A, van der Veen DR. Transient anhedonia phenotype and altered circadian timing of behaviour during night-time dim light exposure in Per3(-/-) mice, but not wildtype mice. Scientific Reports. 7: 40399. PMID 28071711 DOI: 10.1038/srep40399  1
2017 Gould TD, Zanos P, Zarate CA. Ketamine Mechanism of Action: Separating the Wheat from the Chaff. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 42: 368-369. PMID 27909322 DOI: 10.1038/npp.2016.210  1
2016 Zanos P, Moaddel R, Morris PJ, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA, Gould TD. Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine. Biological Psychiatry. PMID 27817846 DOI: 10.1016/j.biopsych.2016.08.039  1
2016 Can A, Zanos P, Moaddel R, Kang HJ, Dossou KS, Wainer IW, Cheer JF, Frost DO, Huang XP, Gould TD. Effects of ketamine and ketamine metabolites on evoked striatal dopamine release, dopamine receptors, and monoamine transporters. The Journal of Pharmacology and Experimental Therapeutics. PMID 27469513 DOI: 10.1124/jpet.116.235838  0.52
2016 Georgiou P, Zanos P, Hourani S, Kitchen I, Bailey A. Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding. The European Journal of Neuroscience. PMID 27453431 DOI: 10.1111/ejn.13348  1
2016 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature. PMID 27144355 DOI: 10.1038/nature17998  0.52
2016 Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Laorden ML, Bailey A. Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype. Neuropharmacology. PMID 26896754 DOI: 10.1016/j.neuropharm.2016.02.012  1
2016 Zanos P, Georgiou P, Rojo Gonzalez L, Hourani S, Chen Y, Kitchen I, Kieffer BL, Winsky-Sommerer R, Bailey A. Emotional impairment and persistent up-regulation of mGlu5 receptor following morphine abstinence: implications of an mGlu5-MOPr interaction. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26861145 DOI: 10.1093/ijnp/pyw011  1
2015 Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Kieffer BL, Laorden ML, Bailey A. The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26475574 DOI: 10.1016/j.euroneuro.2015.09.015  0.52
2015 Zanos P, Piantadosi SC, Wu HQ, Pribut HJ, Dell MJ, Can A, Snodgrass HR, Zarate CA, Schwarcz R, Gould TD. The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition. The Journal of Pharmacology and Experimental Therapeutics. 355: 76-85. PMID 26265321 DOI: 10.1124/jpet.115.225664  0.52
2015 Zanos P, Georgiou P, Metaxas A, Kitchen I, Winsky-Sommerer R, Bailey A. Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration. Neuroscience Letters. 600: 33-7. PMID 26037668 DOI: 10.1016/j.neulet.2015.05.054  0.52
2015 Zanos P, Bhat S, Terrillion CE, Smith RJ, Tonelli LH, Gould TD. Sex-dependent modulation of age-related cognitive decline by the L-type calcium channel gene Cacna1c (Cav 1.2). The European Journal of Neuroscience. PMID 25989111 DOI: 10.1111/ejn.12952  1
2015 Wright SR, Zanos P, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine. Addiction Biology. PMID 25975203 DOI: 10.1111/adb.12259  0.52
2014 Georgiou P, Zanos P, Ehteramyan M, Hourani S, Kitchen I, Maldonado R, Bailey A. Differential regulation of mGlu5 R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice. Addiction Biology. PMID 25522112 DOI: 10.1111/adb.12208  0.52
2014 Chao MR, Fragou D, Zanos P, Hu CW, Bailey A, Kouidou S, Kovatsi L. Epigenetically modified nucleotides in chronic heroin and cocaine treated mice. Toxicology Letters. 229: 451-7. PMID 25064621 DOI: 10.1016/j.toxlet.2014.07.023  0.48
2014 Zanos P, Georgiou P, Wright SR, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 855-65. PMID 24129263 DOI: 10.1038/npp.2013.285  0.52
2014 Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism. Pharmacology, Biochemistry, and Behavior. 119: 72-9. PMID 23680573 DOI: 10.1016/j.pbb.2013.05.009  0.52
2013 Fragou D, Zanos P, Kouidou S, Njau S, Kitchen I, Bailey A, Kovatsi L. Effect of chronic heroin and cocaine administration on global DNA methylation in brain and liver. Toxicology Letters. 218: 260-5. PMID 23454526 DOI: 10.1016/j.toxlet.2013.01.022  0.52
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