Elazer R. Edelman - Publications

Affiliations: 
Health Sciences and Technology Massachusetts Institute of Technology, Cambridge, MA, United States 
Website:
http://edelmanlab.mit.edu/elazer-edelman

220 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tzafriri AR, Muraj B, Garcia-Polite F, Salazar-Martín AG, Markham P, Zani B, Spognardi A, Albaghdadi M, Alston S, Edelman ER. Balloon-based drug coating delivery to the artery wall is dictated by coating micro-morphology and angioplasty pressure gradients. Biomaterials. 260: 120337. PMID 32937269 DOI: 10.1016/J.Biomaterials.2020.120337  0.304
2020 Chowdhury MM, Singh K, Albaghdadi MS, Khraishah H, Mauskapf A, Kessinger CW, Osborn EA, Kellnberger S, Piao Z, Lino Cardenas CL, Grau MS, Jaff MR, Rosenfield K, Libby P, Edelman ER, et al. Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits. Jacc. Basic to Translational Science. 5: 685-695. PMID 32760856 DOI: 10.1016/J.Jacbts.2020.04.007  0.308
2020 Tzafriri AR, Nezami FR, Edelman ER. CRT-500.06 Computational Prediction of Drug-Eluting Stent Performance in Patient-Specific Arteries: A Virtual Reality Jacc-Cardiovascular Interventions. 13. DOI: 10.1016/J.Jcin.2020.01.137  0.317
2019 Dikici S, Aldemir Dikici B, Bhaloo SI, Balcells M, Edelman ER, MacNeil S, Reilly GC, Sherborne C, Claeyssens F. Assessment of the Angiogenic Potential of 2-Deoxy-D-Ribose Using a Novel 3D Dynamic Model in Comparison With Established Assays. Frontiers in Bioengineering and Biotechnology. 7: 451. PMID 32010677 DOI: 10.3389/Fbioe.2019.00451  0.33
2019 Tzafriri AR, Parikh SA, Edelman ER. Taking paclitaxel coated balloons to a higher level: Predicting coating dissolution kinetics, tissue retention and dosing dynamics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 310: 94-102. PMID 31430500 DOI: 10.1016/J.Jconrel.2019.08.019  0.344
2019 Chen C, Chen J, Wu W, Shi Y, Jin L, Petrini L, Shen L, Yuan G, Ding W, Ge J, Edelman ER, Migliavacca F. In vivo and in vitro evaluation of a biodegradable magnesium vascular stent designed by shape optimization strategy. Biomaterials. 221: 119414. PMID 31419654 DOI: 10.1016/J.Biomaterials.2019.119414  0.332
2019 Kalluri AS, Vellarikkal SK, Edelman ER, Nguyen L, Subramanian A, Ellinor PT, Regev A, Kathiresan S, Gupta RM. Single Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations. Circulation. PMID 31146585 DOI: 10.1161/Circulationaha.118.038362  0.315
2019 El-Kurdi M, Soletti L, McGrath J, Linhares S, Rousselle S, Greisler H, Edelman E, Schoen FJ. Functional remodeling of an electrospun polydimethylsiloxane-based polyether urethane external vein graft support device in an ovine model. Journal of Biomedical Materials Research. Part A. PMID 31094084 DOI: 10.1002/Jbm.A.36724  0.326
2019 Tzafriri A, Parikh SA, Granada J, Edelman E. TCT-261 Identifying Conditions for Very Late Tissue Retention of Paclitaxel: Insights From Mechanistic Computational Modeling Journal of the American College of Cardiology. 74. DOI: 10.1016/J.Jacc.2019.08.331  0.309
2019 Albaghdadi M, Piao Z, Chowdhury M, Osborn E, Mauskapf A, Ahsen O, Tzafriri A, Edelman E, Tearney G, Jaffer FA. TCT-64 Intravascular Molecular-Structural Imaging of Arterial Permeability and Vascular Injury In Vivo: Implications for Drug-Coated Balloon Efficacy Journal of the American College of Cardiology. 74. DOI: 10.1016/J.Jacc.2019.08.099  0.354
2018 Wang PJ, Rikhtegar Nezami F, Gorji MB, Berti F, Petrini L, Wierzbicki T, Migliavacca F, Edelman ER. Effect of working environment and procedural strategies on mechanical performance of bioresorbable vascular scaffolds. Acta Biomaterialia. PMID 30342288 DOI: 10.1016/J.Actbio.2018.10.020  0.308
2018 Conway C, Desany GJ, Bailey LR, Keating JH, Baker BL, Edelman ER. Fracture in drug-eluting stents increases focal intimal hyperplasia in the atherosclerosed rabbit iliac artery. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. PMID 30244502 DOI: 10.1002/Ccd.27726  0.315
2018 Siegel RA, Brown L, Edelman ER, Linhardt RJ. B'reshith. Journal of Controlled Release : Official Journal of the Controlled Release Society. 285: 252-257. PMID 30078756 DOI: 10.1016/j.jconrel.2018.07.005  0.514
2018 Melgar-Lesmes P, Sánchez-Herrero A, Lozano-Juan F, Hernández JMT, Montell E, Jiménez W, Edelman ER, Balcells M. Chondroitin Sulphate Attenuates Atherosclerosis in ApoE Knockout Mice Involving Cellular Regulation of the Inflammatory Response. Thrombosis and Haemostasis. PMID 29874688 DOI: 10.1055/S-0038-1657753  0.318
2018 Lopez-Moya M, Melgar-Lesmes P, Kolandaivelu K, de la Torre Hernandez JM, Edelman ER, Balcells M. Optimizing glutaraldehyde-fixed tissue heart valves with chondroitin sulfate hydrogel for endothelialization and shield against deterioration. Biomacromolecules. PMID 29539266 DOI: 10.1021/Acs.Biomac.8B00077  0.332
2018 Song HG, Rumma RT, Ozaki CK, Edelman ER, Chen CS. Vascular Tissue Engineering: Progress, Challenges, and Clinical Promise. Cell Stem Cell. 22: 340-354. PMID 29499152 DOI: 10.1016/J.Stem.2018.02.009  0.326
2018 Brown J, O'Brien CC, Lopes AC, Kolandaivelu K, Edelman ER. Quantification of thrombus formation in malapposed coronary stents deployed in vitro through imaging analysis. Journal of Biomechanics. PMID 29452756 DOI: 10.1016/J.Jbiomech.2018.01.044  0.32
2018 Tzafriri AR, Garcia-Polite F, Li X, Keating J, Balaguer JM, Zani B, Bailey L, Markham P, Kiorpes TC, Carlyle W, Edelman ER. Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29421608 DOI: 10.1016/J.Jconrel.2018.02.007  0.309
2018 Kunio M, Wong G, Markham PM, Edelman ER. Sex differences in the outcomes of stent implantation in mini-swine model. Plos One. 13: e0192004. PMID 29377941 DOI: 10.1371/Journal.Pone.0192004  0.308
2018 Miyakawa AA, Girao-Silva T, Krieger JE, Edelman ER. Rapamycin activates TGF receptor independently of its ligand: implications for endothelial dysfunction. Clinical Science (London, England : 1979). PMID 29343616 DOI: 10.1042/Cs20171457  0.314
2018 Tzafriri A, Daurella LR, Keating J, Li X, Gacia-Polite F, Bailey L, Markham P, Dutta D, Stoll H, Edelman E. TCT-508 Tracking tissue distribution and retention of Sirolimus and analog delivered from polymer free drug coated stents Journal of the American College of Cardiology. 72: B204. DOI: 10.1016/J.Jacc.2018.08.1686  0.346
2017 Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, ... ... Edelman ER, et al. Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Science Translational Medicine. 9. PMID 29167396 DOI: 10.1126/Scitranslmed.Aam8475  0.312
2017 Saemisch M, Nickmann M, Riesinger L, Edelman ER, Methe H. 3D matrix embedding inhibits cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis of human endothelial cells. Journal of Tissue Engineering and Regenerative Medicine. PMID 29131527 DOI: 10.1002/Term.2609  0.33
2017 Tzafriri AR, Garcia-Polite F, Zani B, Stanley J, Muraj B, Knutson J, Kohler R, Markham P, Nikanorov A, Edelman ER. Calcified plaque modification alters local drug delivery in the treatment of peripheral atherosclerosis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28867375 DOI: 10.1016/J.Jconrel.2017.08.037  0.321
2017 Kandzari DE, Smits PC, Love MP, Ben-Yehuda O, Banai S, Robinson SD, Jonas M, Kornowski R, Bagur R, Iniguez A, Danenberg HD, Feldman RL, Jauhar R, Chandna H, Parikh MA, ... ... Edelman E, et al. Randomized Comparison of Ridaforolimus-Eluting and Zotarolimus-Eluting Coronary Stents in Patients with Coronary Artery Disease: Primary Results from the BIONICS Trial. Circulation. PMID 28794001 DOI: 10.1161/Circulationaha.117.028885  0.311
2017 Conway C, McGarry JP, Edelman ER, McHugh PE. Numerical Simulation of Stent Angioplasty with Predilation: An Investigation into Lesion Constitutive Representation and Calcification Influence Annals of Biomedical Engineering. 45: 2244-2252. PMID 28488215 DOI: 10.1007/S10439-017-1851-3  0.359
2017 Bangalore S, Edelman ER, Bhatt DL. First-Generation Bioresorbable Vascular Scaffolds: Disappearing Stents or Disappearing Evidence? Journal of the American College of Cardiology. PMID 28412390 DOI: 10.1016/J.Jacc.2017.04.012  0.345
2017 Williams D, Edelman ER, Radisic M, Laurencin C, Untereker D. Engagement of the medical-technology sector with society. Science Translational Medicine. 9. PMID 28404862 DOI: 10.1126/Scitranslmed.Aal4359  0.421
2017 Unterman S, Charles LF, Strecker SE, Kramarenko D, Pivovarchik D, Edelman ER, Artzi N. Hydrogel Nanocomposites with Independently Tunable Rheology and Mechanics. Acs Nano. PMID 28221760 DOI: 10.1021/Acsnano.6B06730  0.33
2017 Karanasiou GS, Papafaklis MI, Conway C, Michalis LK, Tzafriri R, Edelman ER, Fotiadis DI. Stents: Biomechanics, Biomaterials, and Insights from Computational Modeling. Annals of Biomedical Engineering. PMID 28160103 DOI: 10.1007/S10439-017-1806-8  0.359
2017 Tzafriri A, Gacia-Polite F, Li X, Keating J, Balaguer JM, Zani B, Bailey L, Markham P, Kiorpes T, Edelman E. TCT-93 Stent based tissue drug and binding target protein distributions: durable versus deployable coatings Journal of the American College of Cardiology. 70. DOI: 10.1016/J.Jacc.2017.09.150  0.303
2016 Nakamura K, Keating JH, Edelman ER. Pathology of Endovascular Stents Interventional Cardiology Clinics. 5: 391-403. PMID 28582036 DOI: 10.1016/J.Iccl.2016.02.006  0.346
2016 Tzafriri AR, Edelman ER. Endovascular Drug Delivery and Drug Elution Systems: First Principles Interventional Cardiology Clinics. 5: 307-320. PMID 28582029 DOI: 10.1016/J.Iccl.2016.02.007  0.336
2016 Kolandaivelu K, Bailey L, Buzzi S, Zucker A, Milleret V, Ziogas A, Ehrbar M, Khattab AA, Stanley JR, Wong GK, Zani B, Markham PM, Tzafriri AR, Bhatt DL, Edelman ER. Ultra-Hydrophilic Stent Platforms Promote Early Vascular Healing and Minimize Late Tissue Response - A Potential Alternative to Second-Generation Drug Eluting Stents. Eurointervention : Journal of Europcr in Collaboration With the Working Group On Interventional Cardiology of the European Society of Cardiology. PMID 27993749 DOI: 10.4244/Eij-D-15-00497  0.341
2016 Antoniadis AP, Papafaklis MI, Takahashi S, Shishido K, Andreou I, Chatzizisis YS, Tsuda M, Mizuno S, Makita Y, Domei T, Ikemoto T, Coskun AU, Honye J, Nakamura S, Saito S, ... Edelman ER, et al. Arterial Remodeling and Endothelial Shear Stress Exhibit Significant Longitudinal Heterogeneity Along the Length of Coronary Plaques. Jacc. Cardiovascular Imaging. 9: 1007-9. PMID 27491487 DOI: 10.1016/J.Jcmg.2016.04.003  0.347
2016 Rikhtegar F, Edelman ER, Olgac U, Poulikakos D, Kurtcuoglu V. Drug deposition in coronary arteries with overlapping drug-eluting stents. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27432751 DOI: 10.1016/J.Jconrel.2016.07.023  0.351
2016 Indolfi L, Ligorio M, Ting DT, Xega K, Tzafriri AR, Bersani F, Aceto N, Thapar V, Fuchs BC, Deshpande V, Baker AB, Ferrone CR, Haber DA, Langer R, Clark JW, ... Edelman ER, et al. A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma. Biomaterials. 93: 71-82. PMID 27082874 DOI: 10.1016/J.Biomaterials.2016.03.044  0.5
2016 O'Brien CC, Lopes AC, Kolandaivelu K, Kunio M, Brown J, Kolachalama VB, Conway C, Bailey L, Markham P, Costa M, Ware J, Edelman ER. Vascular Response to Experimental Stent Malapposition and Under-Expansion. Annals of Biomedical Engineering. PMID 26732391 DOI: 10.1007/S10439-015-1518-X  0.339
2016 Bailey L, Gilvarry M, Holian M, Tzafriri A, Stanley J, Edelman E. E-080 Preclinical Evaluation of Mechanical Thrombectomy Devices in a Swine Clot Model Journal of Neurointerventional Surgery. 8. DOI: 10.1136/Neurintsurg-2016-012589.152  0.329
2016 Nakamura K, Bailey L, Grintz T, Keating J, Edelman ER. CRT-300.06 Efficacy and Histomorphologic Evaluation of a Novel Large Bore Vascular Closure Device in Swine Jacc-Cardiovascular Interventions. 9. DOI: 10.1016/J.Jcin.2015.12.156  0.308
2016 Nezami FR, Athanasiou LS, Edelman ER. Endovascular drug-delivery and drug-elution systems Interventional Cardiology Clinics. 5: 307-320. DOI: 10.1016/B978-0-12-817195-0.00028-7  0.348
2015 Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA. Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo. European Heart Journal. PMID 26685129 DOI: 10.1093/Eurheartj/Ehv677  0.306
2015 Falcão BA, Falcão JL, Morais GR, Silva RC, Lopes AC, Soares PR, Mariani J, Kalil-Filho R, Edelman ER, Lemos PA. A Novel Algorithm to Quantify Coronary Remodeling Using Inferred Normal Dimensions. Arquivos Brasileiros De Cardiologia. 105: 390-8. PMID 26559986 DOI: 10.5935/Abc.20150098  0.327
2015 Unterman S, Freiman A, Beckerman M, Abraham E, Stanley JR, Levy E, Artzi N, Edelman E. Cell-Substrate Interactions: Tuning of Collagen Scaffold Properties Modulates Embedded Endothelial Cell Regulatory Phenotype in Repair of Vascular Injuries In Vivo (Adv. Healthcare Mater. 15/2015). Advanced Healthcare Materials. 4: 2180. PMID 26503521 DOI: 10.1002/Adhm.201570087  0.343
2015 Faucher KM, Artzi N, Beck M, Beckerman R, Moodie G, Albergo T, Conroy S, Dale A, Corbeil S, Martakos P, Edelman ER. Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials. Annals of Biomedical Engineering. PMID 26502170 DOI: 10.1007/S10439-015-1489-Y  0.319
2015 Everett KD, Conway C, Desany GJ, Baker BL, Choi G, Taylor CA, Edelman ER. Structural Mechanics Predictions Relating to Clinical Coronary Stent Fracture in a 5 Year Period in FDA MAUDE Database. Annals of Biomedical Engineering. PMID 26467552 DOI: 10.1007/S10439-015-1476-3  0.311
2015 Unterman S, Freiman A, Beckerman M, Abraham E, Stanley JR, Levy E, Artzi N, Edelman E. Tuning of Collagen Scaffold Properties Modulates Embedded Endothelial Cell Regulatory Phenotype in Repair of Vascular Injuries In Vivo. Advanced Healthcare Materials. PMID 26333178 DOI: 10.1002/Adhm.201500457  0.382
2015 Antoniadis AP, Mortier P, Kassab G, Dubini G, Foin N, Murasato Y, Giannopoulos AA, Tu S, Iwasaki K, Hikichi Y, Migliavacca F, Chiastra C, Wentzel JJ, Gijsen F, Reiber JH, ... ... Edelman ER, et al. Biomechanical Modeling to Improve Coronary Artery Bifurcation Stenting: Expert Review Document on Techniques and Clinical Implementation. Jacc. Cardiovascular Interventions. 8: 1281-96. PMID 26315731 DOI: 10.1016/J.Jcin.2015.06.015  0.317
2015 Artzi N, Tzafriri AR, Faucher KM, Moodie G, Albergo T, Conroy S, Corbeil S, Martakos P, Virmani R, Edelman ER. Sustained Efficacy and Arterial Drug Retention by a Fast Drug Eluting Cross-Linked Fatty Acid Coronary Stent Coating. Annals of Biomedical Engineering. PMID 26314990 DOI: 10.1007/S10439-015-1435-Z  0.336
2015 Vijayaratnam PR, O'Brien CC, Reizes JA, Barber TJ, Edelman ER. The Impact of Blood Rheology on Drug Transport in Stented Arteries: Steady Simulations. Plos One. 10: e0128178. PMID 26066041 DOI: 10.1371/Journal.Pone.0128178  0.31
2015 Shivanna S, Kolandaivelu K, Shashar M, Belghasim M, Al-Rabadi L, Balcells M, Zhang A, Weinberg J, Francis J, Pollastri MP, Edelman ER, Sherr DH, Chitalia VC. The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia. Journal of the American Society of Nephrology : Jasn. PMID 26019318 DOI: 10.1681/Asn.2014121241  0.318
2015 Kolandaivelu K, O'Brien CC, Shazly T, Edelman ER, Kolachalama VB. Enhancing physiologic simulations using supervised learning on coarse mesh solutions. Journal of the Royal Society, Interface / the Royal Society. 12: 20141073. PMID 25652458 DOI: 10.1098/Rsif.2014.1073  0.599
2015 Oliva N, Carcole M, Beckerman M, Seliktar S, Hayward A, Stanley J, Parry NM, Edelman ER, Artzi N. Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia. Science Translational Medicine. 7: 272ra11. PMID 25632035 DOI: 10.1126/Scitranslmed.Aaa1616  0.744
2015 Andreou I, Antoniadis AP, Shishido K, Papafaklis MI, Koskinas KC, Chatzizisis YS, Coskun AU, Edelman ER, Feldman CL, Stone PH. How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial shear stress. Journal of Cardiovascular Pharmacology and Therapeutics. 20: 261-75. PMID 25336461 DOI: 10.1177/1074248414555005  0.342
2015 Kolandaivelu K, Bailey L, Buzzi S, Zucker A, Ziogas A, Milleret V, Ehrbar M, Khattab AA, Stanley JRL, Wong GK, Zani B, Markham PK, Tzafriri AR, Bhatt DL, Edelman ER. CRT-704 Ultra-Hydrophilic Stents Promote Early Healing and Minimize Late Tissue Response: A Potential Alternative to Second-Generation Drug Eluting Stents Jacc-Cardiovascular Interventions. 8. DOI: 10.1016/J.Jcin.2014.12.174  0.331
2015 Stanley JR, Regan K, LaRochelle A, Zani BG, Markham PM, Bailey L, Spognardi A, Wong G, Tzafriri AR, Kopia GA, Edelman ER. CRT-306 Particulates from Hydrophilic Coated Guiding Sheaths Embolize to the Brain Jacc-Cardiovascular Interventions. 8. DOI: 10.1016/J.Jcin.2014.12.129  0.325
2014 Maslov MY, Edelman ER, Pezone MJ, Wei AE, Wakim MG, Murray MR, Tsukada H, Gerogiannis IS, Groothuis A, Lovich MA. Myocardial drug distribution generated from local epicardial application: potential impact of cardiac capillary perfusion in a swine model using epinephrine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 194: 257-65. PMID 25234821 DOI: 10.1016/J.Jconrel.2014.09.012  0.342
2014 Martorell J, Santomá P, Kolandaivelu K, Kolachalama VB, Melgar-Lesmes P, Molins JJ, Garcia L, Edelman ER, Balcells M. Extent of flow recirculation governs expression of atherosclerotic and thrombotic biomarkers in arterial bifurcations. Cardiovascular Research. 103: 37-46. PMID 24841070 DOI: 10.1093/Cvr/Cvu124  0.324
2014 Kolandaivelu K, Leiden BB, Edelman ER. Predicting response to endovascular therapies: dissecting the roles of local lesion complexity, systemic comorbidity, and clinical uncertainty. Journal of Biomechanics. 47: 908-21. PMID 24495755 DOI: 10.1016/J.Jbiomech.2014.01.006  0.329
2014 Ligorio M, Indolfi L, Ting DT, Xega K, Aceto N, Bersani F, Ferrone CR, Haber DA, Langer R, Edelman ER, Clark JW. Abstract 4584: A novel drug-eluting platform for localized treatment of pancreatic cancer Cancer Research. 74: 4584-4584. DOI: 10.1158/1538-7445.Am2014-4584  0.506
2013 Koskinas KC, Chatzizisis YS, Papafaklis MI, Coskun AU, Baker AB, Jarolim P, Antoniadis A, Edelman ER, Stone PH, Feldman CL. Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs. International Journal of Cardiology. 169: 394-401. PMID 24148915 DOI: 10.1016/J.Ijcard.2013.10.021  0.301
2013 Maslov MY, Edelman ER, Wei AE, Pezone MJ, Lovich MA. High concentrations of drug in target tissues following local controlled release are utilized for both drug distribution and biologic effect: an example with epicardial inotropic drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 171: 201-7. PMID 23872515 DOI: 10.1016/J.Jconrel.2013.06.038  0.333
2013 Rosàs E, Santomá P, Duran-Frigola M, Hernandez B, Llinàs MC, Ruiz-González R, Nonell S, Sánchez-García D, Edelman ER, Balcells M. Modifications of microvascular EC surface modulate phototoxicity of a porphycene anti-ICAM-1 immunoconjugate; therapeutic implications. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 9734-43. PMID 23844929 DOI: 10.1021/La401067D  0.332
2013 Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH. Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1494-504. PMID 23640495 DOI: 10.1161/Atvbaha.112.300827  0.342
2013 Kolachalama VB, Pacetti SD, Franses JW, Stankus JJ, Zhao HQ, Shazly T, Nikanorov A, Schwartz LB, Tzafriri AR, Edelman ER. Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy. Circulation. 127: 2047-55. PMID 23584359 DOI: 10.1161/Circulationaha.113.002051  0.646
2013 O'Brien CC, Kolachalama VB, Barber TJ, Simmons A, Edelman ER. Impact of flow pulsatility on arterial drug distribution in stent-based therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 168: 115-24. PMID 23541929 DOI: 10.1016/J.Jconrel.2013.03.014  0.34
2013 Franses JW, Drosu NC, Gibson WJ, Chitalia VC, Edelman ER. Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. International Journal of Cancer. Journal International Du Cancer. 133: 1334-44. PMID 23463345 DOI: 10.1002/Ijc.28146  0.329
2013 Banai S, Finkelstein A, Almagor Y, Assali A, Hasin Y, Rosenschein U, Apruzzese P, Lansky AJ, Kume T, Edelman ER. Targeted anti-inflammatory systemic therapy for restenosis: the Biorest Liposomal Alendronate with Stenting sTudy (BLAST)-a double blind, randomized clinical trial. American Heart Journal. 165: 234-40.e1. PMID 23351827 DOI: 10.1016/J.Ahj.2012.10.023  0.312
2013 Chitalia VC, Shivanna S, Martorell J, Balcells M, Bosch I, Kolandaivelu K, Edelman ER. Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor. Circulation. 127: 365-76. PMID 23269489 DOI: 10.1161/Circulationaha.112.118174  0.327
2013 Orekhov AN, Sobenin IA, Korneev NV, Kirichenko TV, Myasoedova VA, Melnichenko AA, Balcells M, Edelman ER, Bobryshev YV. Anti-atherosclerotic therapy based on botanicals. Recent Patents On Cardiovascular Drug Discovery. 8: 56-66. PMID 23176379 DOI: 10.2174/18722083113079990008  0.332
2013 Murikipudi S, Methe H, Edelman ER. The effect of substrate modulus on the growth and function of matrix-embedded endothelial cells. Biomaterials. 34: 677-84. PMID 23102623 DOI: 10.1016/J.Biomaterials.2012.09.079  0.343
2013 Artzi N, Edelman ER. Aldehyde-amine chemistry enables tissue adhesive materials to respond to physiologic variation and pathologic states Israel Journal of Chemistry. 53: 748-755. DOI: 10.1002/Ijch.201300081  0.314
2012 Oliva N, Shitreet S, Abraham E, Stanley B, Edelman ER, Artzi N. Natural tissue microenvironmental conditions modulate adhesive material performance. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 15402-9. PMID 23046479 DOI: 10.1021/La303155P  0.739
2012 Carlyle WC, McClain JB, Tzafriri AR, Bailey L, Zani BG, Markham PM, Stanley JR, Edelman ER. Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug. Journal of Controlled Release : Official Journal of the Controlled Release Society. 162: 561-7. PMID 22800575 DOI: 10.1016/J.Jconrel.2012.07.004  0.342
2012 Indolfi L, Baker AB, Edelman ER. The role of scaffold microarchitecture in engineering endothelial cell immunomodulation. Biomaterials. 33: 7019-27. PMID 22796162 DOI: 10.1016/J.Biomaterials.2012.06.052  0.359
2012 Nugent HM, Ng YS, White D, Groothius A, Kanner G, Edelman ER. Ultrasound-guided percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model. Journal of Vascular Surgery. 56: 1078-88. PMID 22796118 DOI: 10.1016/J.Jvs.2012.03.002  0.388
2012 Tzafriri AR, Groothuis A, Price GS, Edelman ER. Stent elution rate determines drug deposition and receptor-mediated effects. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 918-26. PMID 22642931 DOI: 10.1016/J.Jconrel.2012.05.039  0.335
2012 Martorell J, Santomá P, Molins JJ, García-Granada AA, Bea JA, Edelman ER, Balcells M. Engineered arterial models to correlate blood flow to tissue biological response. Annals of the New York Academy of Sciences. 1254: 51-6. PMID 22548569 DOI: 10.1111/J.1749-6632.2012.06518.X  0.324
2012 Baker AB, Gibson WJ, Kolachalama VB, Golomb M, Indolfi L, Spruell C, Zcharia E, Vlodavsky I, Edelman ER. Heparanase regulates thrombosis in vascular injury and stent-induced flow disturbance. Journal of the American College of Cardiology. 59: 1551-60. PMID 22516446 DOI: 10.1016/J.Jacc.2011.11.057  0.352
2012 Jang E, Albadawi H, Watkins MT, Edelman ER, Baker AB. Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. Proceedings of the National Academy of Sciences of the United States of America. 109: 1679-84. PMID 22307630 DOI: 10.1073/Pnas.1117885109  0.346
2012 Shazly T, Kolachalama VB, Ferdous J, Oberhauser JP, Hossainy S, Edelman ER. Assessment of material by-product fate from bioresorbable vascular scaffolds. Annals of Biomedical Engineering. 40: 955-65. PMID 22042625 DOI: 10.1007/S10439-011-0445-8  0.77
2012 Tzafriri A, Bailey L, Stanley J, Zani B, Markham P, Carlyle W, McClain J, Edelman E. TCT-570 Stents With Absorbable Tissue-Deployable Coatings Can Distribute Drug More Uniformly Between Struts Journal of the American College of Cardiology. 60: B166. DOI: 10.1016/J.Jacc.2012.08.605  0.305
2011 Franses JW, Edelman ER. The evolution of endothelial regulatory paradigms in cancer biology and vascular repair. Cancer Research. 71: 7339-44. PMID 22144472 DOI: 10.1158/0008-5472.Can-11-1718  0.315
2011 Artzi N, Oliva N, Puron C, Shitreet S, Artzi S, bon Ramos A, Groothuis A, Sahagian G, Edelman ER. In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging. Nature Materials. 10: 704-9. PMID 21857678 DOI: 10.1038/Nmat3095  0.744
2011 Chitalia VC, Murikipudi S, Indolfi L, Rabadi L, Valdez R, Franses JW, Edelman ER. Matrix-embedded endothelial cells are protected from the uremic milieu. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 26: 3858-65. PMID 21795755 DOI: 10.1093/Ndt/Gfr337  0.339
2011 Kolandaivelu K, Swaminathan R, Gibson WJ, Kolachalama VB, Nguyen-Ehrenreich KL, Giddings VL, Coleman L, Wong GK, Edelman ER. Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings. Circulation. 123: 1400-9. PMID 21422389 DOI: 10.1161/Circulationaha.110.003210  0.33
2011 Chatzizisis YS, Baker AB, Sukhova GK, Koskinas KC, Papafaklis MI, Beigel R, Jonas M, Coskun AU, Stone BV, Maynard C, Shi GP, Libby P, Feldman CL, Edelman ER, Stone PH. Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation. 123: 621-30. PMID 21282495 DOI: 10.1161/Circulationaha.110.970038  0.338
2011 Schubert SY, Benarroch A, Monter-Solans J, Edelman ER. Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 870-5. PMID 21273558 DOI: 10.1161/Atvbaha.110.218255  0.324
2011 Artzi N, Zeiger A, Boehning F, bon Ramos A, Van Vliet K, Edelman ER. Tuning adhesion failure strength for tissue-specific applications. Acta Biomaterialia. 7: 67-74. PMID 20624496 DOI: 10.1016/J.Actbio.2010.07.008  0.31
2011 Kolandaivelu K, Swaminathan R, Gibson WJ, Kolachalama VB, Nguyen-Ehrenreich KL, Giddings VL, Coleman L, Wong GK, Edelman ER. Response to letter regarding article, "stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings" Circulation. 124: e512. DOI: 10.1161/Circulationaha.111.051102  0.333
2011 Kalcioglu ZI, Qu M, Strawhecker KE, Shazly T, Edelman E, Vanlandingham MR, Smith JF, Van Vliet KJ. Dynamic impact indentation of hydrated biological tissues and tissue surrogate gels Philosophical Magazine. 91: 1339-1355. DOI: 10.1080/14786435.2010.512574  0.614
2010 Baker AB, Chatzizisis YS, Beigel R, Jonas M, Stone BV, Coskun AU, Maynard C, Rogers C, Koskinas KC, Feldman CL, Stone PH, Edelman ER. Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine. Atherosclerosis. 213: 436-42. PMID 20950809 DOI: 10.1016/J.Atherosclerosis.2010.09.003  0.33
2010 Shazly TM, Baker AB, Naber JR, Bon A, Van Vliet KJ, Edelman ER. Augmentation of postswelling surgical sealant potential of adhesive hydrogels. Journal of Biomedical Materials Research. Part A. 95: 1159-69. PMID 20878989 DOI: 10.1002/Jbm.A.32942  0.607
2010 Balcells M, Martorell J, Olivé C, Santacana M, Chitalia V, Cardoso AA, Edelman ER. Smooth muscle cells orchestrate the endothelial cell response to flow and injury. Circulation. 121: 2192-9. PMID 20458015 DOI: 10.1161/Circulationaha.109.877282  0.347
2010 Koskinas KC, Feldman CL, Chatzizisis YS, Coskun AU, Jonas M, Maynard C, Baker AB, Papafaklis MI, Edelman ER, Stone PH. Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study. Circulation. 121: 2092-101. PMID 20439786 DOI: 10.1161/Circulationaha.109.901678  0.337
2010 Kolachalama VB, Tzafriri AR, Arifin DY, Edelman ER. Corrigendum to “Luminal flow patterns dictate arterial drug deposition in stent-based delivery” [Journal of Controlled Release. 133(2009) 24–30]☆ Journal of Controlled Release. 146: 160-160. DOI: 10.1016/J.Jconrel.2010.05.007  0.324
2009 Artzi N, Shazly T, Baker AB, Bon A, Edelman ER. Aldehyde-amine chemistry enables modulated biosealants with tissue-specific adhesion. Advanced Materials (Deerfield Beach, Fla.). 21: 3399-403. PMID 20882504 DOI: 10.1002/Adma.200900340  0.599
2009 Artzi N, Shazly T, Baker AB, Bon A, Edelman ER. Aldehyde-amine chemistry enables modulated biosealants with tissue-specific adhesion. Advanced Materials (Deerfield Beach, Fla.). 21: 3399-403. PMID 20882504 DOI: 10.1002/Adma.200900340  0.599
2009 Artzi N, Shazly T, Crespo C, Ramos AB, Chenault HK, Edelman ER. Characterization of star adhesive sealants based on PEG/dextran hydrogels. Macromolecular Bioscience. 9: 754-65. PMID 19384975 DOI: 10.1002/Mabi.200800355  0.588
2009 Artzi N, Shazly T, Crespo C, Ramos AB, Chenault HK, Edelman ER. Characterization of star adhesive sealants based on PEG/dextran hydrogels. Macromolecular Bioscience. 9: 754-65. PMID 19384975 DOI: 10.1002/Mabi.200800355  0.588
2009 Baker AB, Groothuis A, Jonas M, Ettenson DS, Shazly T, Zcharia E, Vlodavsky I, Seifert P, Edelman ER. Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Circulation Research. 104: 380-7. PMID 19096032 DOI: 10.1161/Circresaha.108.180695  0.618
2009 Baker AB, Groothuis A, Jonas M, Ettenson DS, Shazly T, Zcharia E, Vlodavsky I, Seifert P, Edelman ER. Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Circulation Research. 104: 380-7. PMID 19096032 DOI: 10.1161/Circresaha.108.180695  0.618
2009 Kolachalama VB, Tzafriri AR, Arifin DY, Edelman ER. Luminal flow patterns dictate arterial drug deposition in stent-based delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 133: 24-30. PMID 18926864 DOI: 10.1016/J.Jconrel.2008.09.075  0.328
2008 Schwartz RS, Edelman E, Virmani R, Carter A, Granada JF, Kaluza GL, Chronos NA, Robinson KA, Waksman R, Weinberger J, Wilson GJ, Wilensky RL. Drug-eluting stents in preclinical studies: updated consensus recommendations for preclinical evaluation. Circulation. Cardiovascular Interventions. 1: 143-53. PMID 20031669 DOI: 10.1161/Circinterventions.108.789974  0.304
2008 Shazly TM, Artzi N, Boehning F, Edelman ER. Viscoelastic adhesive mechanics of aldehyde-mediated soft tissue sealants. Biomaterials. 29: 4584-91. PMID 18804861 DOI: 10.1016/J.Biomaterials.2008.08.032  0.633
2008 Balakrishnan B, Dooley J, Kopia G, Edelman ER. Thrombus causes fluctuations in arterial drug delivery from intravascular stents. Journal of Controlled Release : Official Journal of the Controlled Release Society. 131: 173-80. PMID 18713645 DOI: 10.1016/J.Jconrel.2008.07.027  0.343
2008 Baker AB, Ettenson DS, Jonas M, Nugent MA, Iozzo RV, Edelman ER. Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circulation Research. 103: 289-97. PMID 18583708 DOI: 10.1161/Circresaha.108.179465  0.671
2008 Danenberg HD, Grad E, Swaminathan RV, Chen Z, Seifert P, Szalai AJ, Lotan C, Simon DI, Edelman ER. Neointimal formation is reduced after arterial injury in human crp transgenic mice. Atherosclerosis. 201: 85-91. PMID 18358478 DOI: 10.1016/J.Atherosclerosis.2008.01.013  0.313
2008 Methe H, Hess S, Edelman ER. The effect of three-dimensional matrix-embedding of endothelial cells on the humoral and cellular immune response. Seminars in Immunology. 20: 117-22. PMID 18243732 DOI: 10.1016/J.Smim.2007.12.005  0.329
2008 Epstein H, Grad E, Golomb M, Koroukhov N, Edelman ER, Golomb G, Danenberg HD. Innate immunity has a dual effect on vascular healing: suppression and aggravation of neointimal formation and remodeling post-endotoxin challenge. Atherosclerosis. 199: 41-6. PMID 18067897 DOI: 10.1016/J.Atherosclerosis.2007.10.034  0.336
2008 Schubert SY, Benarroch A, Ostvang J, Edelman ER. Regulation of endothelial cell proliferation by primary monocytes. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 97-104. PMID 17991870 DOI: 10.1161/Atvbaha.107.157537  0.337
2007 Balakrishnan B, Dooley JF, Kopia G, Edelman ER. Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution. Journal of Controlled Release : Official Journal of the Controlled Release Society. 123: 100-8. PMID 17868948 DOI: 10.1016/J.Jconrel.2007.06.025  0.324
2007 Nugent HM, Sjin RT, White D, Milton LG, Manson RJ, Lawson JH, Edelman ER. Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts. Journal of Vascular Surgery. 46: 548-556. PMID 17826244 DOI: 10.1016/J.Jvs.2007.04.074  0.336
2007 Methe H, Hess S, Edelman ER. Endothelial immunogenicity--a matter of matrix microarchitecture. Thrombosis and Haemostasis. 98: 278-82. PMID 17721607 DOI: 10.1160/Th07-01-0043  0.352
2007 Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. Journal of the American College of Cardiology. 49: 2379-93. PMID 17599600 DOI: 10.1016/J.Jacc.2007.02.059  0.352
2007 Hamik A, Lin Z, Kumar A, Balcells M, Sinha S, Katz J, Feinberg MW, Gerzsten RE, Edelman ER, Jain MK. Kruppel-like factor 4 regulates endothelial inflammation. The Journal of Biological Chemistry. 282: 13769-79. PMID 17339326 DOI: 10.1074/Jbc.M700078200  0.32
2007 Thomas AH, Edelman ER, Stultz CM. Collagen fragments modulate innate immunity. Experimental Biology and Medicine (Maywood, N.J.). 232: 406-11. PMID 17327474 DOI: 10.3181/00379727-232-2320406  0.599
2007 Methe H, Groothuis A, Sayegh MH, Edelman ER. Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo- and xenogeneic models. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1515-26. PMID 17264166 DOI: 10.1096/Fj.06-7051Com  0.317
2007 Methe H, Balcells M, Alegret Mdel C, Santacana M, Molins B, Hamik A, Jain MK, Edelman ER. Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expression. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2167-75. PMID 17209004 DOI: 10.1152/Ajpheart.00403.2006  0.33
2006 Methe H, Edelman ER. Cell-matrix contact prevents recognition and damage of endothelial cells in states of heightened immunity. Circulation. 114: I233-8. PMID 16820578 DOI: 10.1161/Circulationaha.105.000687  0.307
2006 Costa LF, Balcells M, Edelman ER, Nadler LM, Cardoso AA. Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB. Blood. 107: 285-92. PMID 16141350 DOI: 10.1182/Blood-2005-06-2208  0.304
2005 Levin AD, Jonas M, Hwang CW, Edelman ER. Local and systemic drug competition in drug-eluting stent tissue deposition properties. Journal of Controlled Release : Official Journal of the Controlled Release Society. 109: 236-43. PMID 16289420 DOI: 10.1016/J.Jconrel.2005.09.041  0.334
2005 Methe H, Nugent HM, Groothuis A, Seifert P, Sayegh MH, Edelman ER. Matrix embedding alters the immune response against endothelial cells in vitro and in vivo. Circulation. 112: I89-95. PMID 16159871 DOI: 10.1161/01.Circulationaha.105.524991  0.324
2005 Balakrishnan B, Tzafriri AR, Seifert P, Groothuis A, Rogers C, Edelman ER. Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents. Circulation. 111: 2958-65. PMID 15927969 DOI: 10.1161/Circulationaha.104.512475  0.322
2005 Hwang CW, Levin AD, Jonas M, Li PH, Edelman ER. Thrombosis modulates arterial drug distribution for drug-eluting stents. Circulation. 111: 1619-26. PMID 15795325 DOI: 10.1161/01.Cir.0000160363.30639.37  0.358
2005 Noh I, Edelman ER. Smooth muscle cell ingrowth of a surface-modified ePTFE vascular graft Key Engineering Materials. 288: 367-370. DOI: 10.4028/Www.Scientific.Net/Kem.288-289.367  0.312
2005 Nugent MA, Forsten-Williams K, Karnovsky MJ, Edelman ER. Mechanisms of cell growth regulation by heparin and heparan sulfate Chemistry and Biology of Heparin and Heparan Sulfate. 533-570. DOI: 10.1016/B978-008044859-6/50020-4  0.688
2004 Schwartz RS, Edelman ER, Carter A, Chronos NA, Rogers C, Robinson KA, Waksman R, Machan L, Weinberger J, Wilensky RL, Goode JL, Hottenstein OD, Zuckerman BD, Virmani R. Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group. Circulation. 110: 2498-505. PMID 15492330 DOI: 10.1161/01.Cir.0000145164.85178.2E  0.342
2004 Kolandaivelu K, Edelman ER. Environmental influences on endovascular stent platelet reactivity: an in vitro comparison of stainless steel and gold surfaces. Journal of Biomedical Materials Research. Part A. 70: 186-93. PMID 15227663 DOI: 10.1002/Jbm.A.30023  0.323
2004 Levin AD, Vukmirovic N, Hwang CW, Edelman ER. Specific binding to intracellular proteins determines arterial transport properties for rapamycin and paclitaxel. Proceedings of the National Academy of Sciences of the United States of America. 101: 9463-7. PMID 15197278 DOI: 10.1073/Pnas.0400918101  0.335
2004 Richter Y, Groothuis A, Seifert P, Edelman ER. Dynamic flow alterations dictate leukocyte adhesion and response to endovascular interventions. The Journal of Clinical Investigation. 113: 1607-14. PMID 15173887 DOI: 10.1172/Jci21007  0.333
2004 Wu D, Edelman ER. Resonance energy transfer for assessing the molecular integrity of proteins for local delivery. Biotechnology and Bioengineering. 85: 406-12. PMID 14755558 DOI: 10.1002/Bit.10902  0.323
2004 Parikh SA, Carofino BC, Lee AC, Groothuis A, Seifert P, Nugent HM, Edelman ER. 1001-6 Tissue engineered endothelial cells inhibit early events in the vascular response to injury to prevent restenosis Journal of the American College of Cardiology. 43. DOI: 10.1016/S0735-1097(04)90005-8  0.335
2003 Janicki C, Hwang CW, Edelman ER. Dose model for stent-based delivery of a radioactive compound for the treatment of restenosis in coronary arteries. Medical Physics. 30: 2622-8. PMID 14596298 DOI: 10.1118/1.1607506  0.359
2003 Stultz CM, Edelman ER. A structural model that explains the effects of hyperglycemia on collagenolysis. Biophysical Journal. 85: 2198-204. PMID 14507685 DOI: 10.1016/S0006-3495(03)74645-1  0.594
2003 Danenberg HD, Szalai AJ, Swaminathan RV, Peng L, Chen Z, Seifert P, Fay WP, Simon DI, Edelman ER. Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation. 108: 512-5. PMID 12874178 DOI: 10.1161/01.Cir.0000085568.13915.1E  0.31
2003 Welt FG, Tso C, Edelman ER, Kjelsberg MA, Paolini JF, Seifert P, Rogers C. Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Vascular Medicine (London, England). 8: 1-7. PMID 12866605 DOI: 10.1191/1358863X03Vm462Oa  0.306
2003 Nugent HM, Edelman ER. Tissue engineering therapy for cardiovascular disease. Circulation Research. 92: 1068-78. PMID 12775655 DOI: 10.1161/01.Res.0000073844.41372.38  0.315
2003 Hwang CW, Wu D, Edelman ER. Impact of transport and drug properties on the local pharmacology of drug-eluting stents. International Journal of Cardiovascular Interventions. 5: 7-12. PMID 12623559 DOI: 10.1080/14628840304614  0.334
2002 Nugent HM, Groothuis A, Seifert P, Guerraro JL, Nedelman M, Mohanakumar T, Edelman ER. Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. Journal of Vascular Research. 39: 524-33. PMID 12566978 DOI: 10.1159/000067207  0.349
2002 Stultz CM, Levin AD, Edelman ER. Phosphorylation-induced conformational changes in a mitogen-activated protein kinase substrate. Implications for tyrosine hydroxylase activation. The Journal of Biological Chemistry. 277: 47653-61. PMID 12361946 DOI: 10.1074/Jbc.M208755200  0.573
2002 Schwartz RS, Edelman ER, Carter A, Chronos N, Rogers C, Robinson KA, Waksman R, Weinberger J, Wilensky RL, Jensen DN, Zuckerman BD, Virmani R. Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group. Circulation. 106: 1867-73. PMID 12356643 DOI: 10.1161/01.Cir.0000033485.20594.6F  0.337
2002 Danenberg HD, Welt FG, Walker M, Seifert P, Toegel GS, Edelman ER. Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbits. Circulation. 105: 2917-22. PMID 12070123 DOI: 10.1161/01.Cir.0000018168.15904.Bb  0.305
2002 Balcells M, Edelman ER. Effect of pre-adsorbed proteins on attachment, proliferation, and function of endothelial cells. Journal of Cellular Physiology. 191: 155-61. PMID 12064458 DOI: 10.1002/Jcp.10087  0.311
2002 Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Circulation Research. 90: 826-32. PMID 11964377 DOI: 10.1161/01.Res.0000016672.26000.9E  0.363
2002 Woods TC, Blystone CR, Yoo J, Edelman ER. Activation of EphB2 and its ligands promotes vascular smooth muscle cell proliferation. The Journal of Biological Chemistry. 277: 1924-7. PMID 11706028 DOI: 10.1074/Jbc.M108189200  0.333
2001 Welt FG, Woods TC, Edelman ER. Oral heparin prevents neointimal hyperplasia after arterial injury: inhibitory potential depends on type of vascular injury. Circulation. 104: 3121-4. PMID 11748111 DOI: 10.1161/Hc5001.100837  0.333
2001 Lovich MA, Creel C, Hong K, Hwang CW, Edelman ER. Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel. Journal of Pharmaceutical Sciences. 90: 1324-35. PMID 11745785 DOI: 10.1002/Jps.1085  0.34
2001 Edelman ER. On causes: Hippocrates, Aristotle, Robert Koch, and the Dread Pirate Roberts. Circulation. 104: 2509-12. PMID 11714642 DOI: 10.1161/Circ.104.21.2509  0.322
2001 Hwang CW, Wu D, Edelman ER. Physiological transport forces govern drug distribution for stent-based delivery. Circulation. 104: 600-5. PMID 11479260 DOI: 10.1161/Hc3101.092214  0.338
2001 Nugent HM, Edelman ER. Endothelial implants provide long-term control of vascular repair in a porcine model of arterial injury. The Journal of Surgical Research. 99: 228-34. PMID 11469891 DOI: 10.1006/Jsre.2001.6198  0.337
2000 Drachman DE, Edelman ER, Seifert P, Groothuis AR, Bornstein DA, Kamath KR, Palasis M, Yang D, Nott SH, Rogers C. Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months. Journal of the American College of Cardiology. 36: 2325-32. PMID 11127480 DOI: 10.1016/S0735-1097(00)01020-2  0.379
2000 Welt FG, Edelman ER, Simon DI, Rogers C. Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteries. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2553-8. PMID 11116052 DOI: 10.1161/01.Atv.20.12.2553  0.327
2000 Edelman ER, Nathan A, Katada M, Gates J, Karnovsky MJ. Perivascular graft heparin delivery using biodegradable polymer wraps. Biomaterials. 21: 2279-86. PMID 11026634 DOI: 10.1016/S0142-9612(00)00154-X  0.576
2000 Elmalak O, Lovich MA, Edelman E. Correlation of transarterial transport of various dextrans with their physicochemical properties. Biomaterials. 21: 2263-72. PMID 11026632 DOI: 10.1016/S0142-9612(00)00152-6  0.303
2000 Ettenson DS, Edelman ER. Local drug delivery: an emerging approach in the treatment of restenosis. Vascular Medicine (London, England). 5: 97-102. PMID 10943586 DOI: 10.1177/1358836X0000500206  0.34
2000 Parikh SA, Edelman ER. Endothelial cell delivery for cardiovascular therapy. Advanced Drug Delivery Reviews. 42: 139-61. PMID 10942819 DOI: 10.1016/S0169-409X(00)00058-2  0.36
2000 Nugent MA, Nugent HM, Iozzo RV, Sanchack K, Edelman ER. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 97: 6722-7. PMID 10841569 DOI: 10.1073/Pnas.97.12.6722  0.693
2000 Ettenson DS, Koo EW, Januzzi JL, Edelman ER. Endothelial heparan sulfate is necessary but not sufficient for control of vascular smooth muscle cell growth. Journal of Cellular Physiology. 184: 93-100. PMID 10825238 DOI: 10.1002/(Sici)1097-4652(200007)184:1<93::Aid-Jcp10>3.0.Co;2-H  0.31
2000 Creel CJ, Lovich MA, Edelman ER. Arterial paclitaxel distribution and deposition. Circulation Research. 86: 879-84. PMID 10785510 DOI: 10.1161/01.Res.86.8.879  0.369
2000 Garasic JM, Edelman ER, Squire JC, Seifert P, Williams MS, Rogers C. Stent and artery geometry determine intimal thickening independent of arterial injury. Circulation. 101: 812-8. PMID 10683357 DOI: 10.1161/01.Cir.101.7.812  0.329
2000 Simon DI, Dhen Z, Seifert P, Edelman ER, Ballantyne CM, Rogers C. Decreased neointimal formation in Mac-1(-/-) mice reveals a role for inflammation in vascular repair after angioplasty. The Journal of Clinical Investigation. 105: 293-300. PMID 10675355 DOI: 10.1172/Jci7811  0.37
2000 Noh I, Lovich MA, Edelman ER. Mechanisms of heparin transport through expanded poly(tetrafluoroethylene) vascular grafts. Journal of Biomedical Materials Research. 49: 112-9. PMID 10559753 DOI: 10.1002/(Sici)1097-4636(200001)49:1<112::Aid-Jbm14>3.0.Co;2-U  0.326
1999 Squire JC, Rogers C, Edelman ER. Measuring arterial strain induced by endovascular stents. Medical & Biological Engineering & Computing. 37: 692-8. PMID 10723874 DOI: 10.1007/Bf02513369  0.328
1999 Edelman ER. Vascular tissue engineering : designer arteries. Circulation Research. 85: 1115-7. PMID 10590236 DOI: 10.1161/01.Res.85.12.1115  0.379
1999 Laham RJ, Sellke FW, Edelman ER, Pearlman JD, Ware JA, Brown DL, Gold JP, Simons M. Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial. Circulation. 100: 1865-71. PMID 10545430 DOI: 10.1161/01.Cir.100.18.1865  0.302
1999 Lovich MA, Edelman ER. Tissue concentration of heparin, not administered dose, correlates with the biological response of injured arteries in vivo. Proceedings of the National Academy of Sciences of the United States of America. 96: 11111-6. PMID 10500138 DOI: 10.1073/Pnas.96.20.11111  0.379
1999 Nugent HM, Rogers C, Edelman ER. Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. Circulation Research. 84: 384-91. PMID 10066672 DOI: 10.1161/01.Res.84.4.384  0.382
1999 Rogers C, Tseng DY, Squire JC, Edelman ER. Balloon-artery interactions during stent placement: a finite element analysis approach to pressure, compliance, and stent design as contributors to vascular injury. Circulation Research. 84: 378-83. PMID 10066671 DOI: 10.1161/01.Res.84.4.378  0.343
1998 Lovich MA, Philbrook M, Sawyer S, Weselcouch E, Edelman ER. Arterial heparin deposition: role of diffusion, convection, and extravascular space. The American Journal of Physiology. 275: H2236-42. PMID 9843824 DOI: 10.1152/Ajpheart.1998.275.6.H2236  0.352
1998 Yu C, Cunningham M, Rogers C, Dinbergs ID, Edelman ER. The biologic effects of growth factor-toxin conjugates in models of vascular injury depend on dose, mode of delivery, and animal species. Journal of Pharmaceutical Sciences. 87: 1300-4. PMID 9811480 DOI: 10.1021/Js980086I  0.389
1998 Tseng DY, Edelman ER. Effects of amide and amine plasma-treated ePTFE vascular grafts on endothelial cell lining in an artificial circulatory system. Journal of Biomedical Materials Research. 42: 188-98. PMID 9773815 DOI: 10.1002/(Sici)1097-4636(199811)42:2<188::Aid-Jbm4>3.0.Co;2-L  0.305
1998 Rogers C, Edelman ER, Simon DI. A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits. Proceedings of the National Academy of Sciences of the United States of America. 95: 10134-9. PMID 9707613 DOI: 10.1073/Pnas.95.17.10134  0.315
1998 Sellke FW, Laham RJ, Edelman ER, Pearlman JD, Simons M. Therapeutic angiogenesis with basic fibroblast growth factor: technique and early results. The Annals of Thoracic Surgery. 65: 1540-4. PMID 9647055 DOI: 10.1016/S0003-4975(98)00340-3  0.346
1998 Edelman ER, Rogers C. Pathobiologic responses to stenting. The American Journal of Cardiology. 81: 4E-6E. PMID 9551587 DOI: 10.1016/S0002-9149(98)00189-1  0.351
1997 Han RO, Ettenson DS, Koo EW, Edelman ER. Heparin/heparan sulfate chelation inhibits control of vascular repair by tissue-engineered endothelial cells. The American Journal of Physiology. 273: H2586-95. PMID 9435591 DOI: 10.1152/Ajpheart.1997.273.6.H2586  0.351
1997 Sirois MG, Simons M, Kuter DJ, Rosenberg RD, Edelman ER. Rat arterial wall retains myointimal hyperplastic potential long after arterial injury. Circulation. 96: 1291-8. PMID 9286961 DOI: 10.1161/01.Cir.96.4.1291  0.345
1997 Sirois MG, Edelman ER. VEGF effect on vascular permeability is mediated by synthesis of platelet-activating factor. The American Journal of Physiology. 272: H2746-56. PMID 9227554 DOI: 10.1152/Ajpheart.1997.272.6.H2746  0.323
1997 Lovich MA, Brown L, Edelman ER. Drug clearance and arterial uptake after local perivascular delivery to the rat carotid artery. Journal of the American College of Cardiology. 29: 1645-50. PMID 9180131 DOI: 10.1016/S0735-1097(97)00123-X  0.347
1997 Welt FG, Edelman ER. Second International Symposium on Cardiovascular Drug Delivery. Circulation. 95: 773-6. PMID 9054725 DOI: 10.1161/01.Cir.95.4.773  0.331
1997 Sirois MG, Simons M, Edelman ER. Antisense oligonucleotide inhibition of PDGFR-beta receptor subunit expression directs suppression of intimal thickening. Circulation. 95: 669-76. PMID 9024156 DOI: 10.1161/01.Cir.95.3.669  0.306
1997 Welt FGP, Edelman ER. Cell cycle regulation and control of angioplasty restenosis Advanced Drug Delivery Reviews. 24: 45-51. DOI: 10.1016/S0169-409X(96)00481-4  0.315
1996 Koo EWY, Edelman ER. Cellular Effects of Antisense c-myc Oligodeoxynucleotides Are Delivery Dependent Drug Delivery. 3: 149-154. PMID 26790910 DOI: 10.3109/10717549609029444  0.316
1996 Brown LR, Edelman ER, Fischel-Ghodsian F, Langer R. Characterization of glucose-mediated insulin release from implantable polymers. Journal of Pharmaceutical Sciences. 85: 1341-5. PMID 8961150 DOI: 10.1021/Js9600686  0.45
1996 Edelman ER, Brown L, Langer R. Quantification of insulin release from implantable polymer-based delivery systems and augmentation of therapeutic effect with simultaneous release of somatostatin. Journal of Pharmaceutical Sciences. 85: 1271-5. PMID 8961137 DOI: 10.1021/Js9601694  0.47
1996 Lovich MA, Edelman ER. Computational simulations of local vascular heparin deposition and distribution. The American Journal of Physiology. 271: H2014-24. PMID 8945921 DOI: 10.1152/Ajpheart.1996.271.5.H2014  0.363
1996 Rogers C, Parikh S, Seifert P, Edelman ER. Endogenous cell seeding. Remnant endothelium after stenting enhances vascular repair. Circulation. 94: 2909-14. PMID 8941120 DOI: 10.1161/01.Cir.94.11.2909  0.374
1996 Dinbergs ID, Brown L, Edelman ER. Cellular response to transforming growth factor-beta1 and basic fibroblast growth factor depends on release kinetics and extracellular matrix interactions. The Journal of Biological Chemistry. 271: 29822-9. PMID 8939921 DOI: 10.1074/Jbc.271.47.29822  0.316
1996 Harada K, Friedman M, Lopez JJ, Wang SY, Li J, Prasad PV, Pearlman JD, Edelman ER, Sellke FW, Simons M. Vascular endothelial growth factor administration in chronic myocardial ischemia. The American Journal of Physiology. 270: H1791-802. PMID 8928888 DOI: 10.1152/Ajpheart.1996.270.5.H1791  0.307
1996 Rogers C, Welt FG, Karnovsky MJ, Edelman ER. Monocyte recruitment and neointimal hyperplasia in rabbits. Coupled inhibitory effects of heparin. Arteriosclerosis, Thrombosis, and Vascular Biology. 16: 1312-8. PMID 8857930 DOI: 10.1161/01.Atv.16.10.1312  0.581
1996 Edelman ER, Rogers C. Hoop dreams. Stents without restenosis. Circulation. 94: 1199-202. PMID 8822967 DOI: 10.1161/01.Cir.94.6.1199  0.357
1996 Lovich MA, Edelman ER. Tissue average binding and equilibrium distribution: an example with heparin in arterial tissues. Biophysical Journal. 70: 1553-9. PMID 8785313 DOI: 10.1016/S0006-3495(96)79719-9  0.32
1995 Edelman ER, Simons M, Sirois MG, Rosenberg RD. c-myc in vasculoproliferative disease. Circulation Research. 76: 176-82. PMID 7834827 DOI: 10.1161/01.Res.76.2.176  0.318
1995 Rogers C, Edelman ER. Endovascular stent design dictates experimental restenosis and thrombosis. Circulation. 91: 2995-3001. PMID 7796511 DOI: 10.1161/01.Cir.91.12.2995  0.337
1995 Nathan A, Nugent MA, Edelman ER. Tissue engineered perivascular endothelial cell implants regulate vascular injury. Proceedings of the National Academy of Sciences of the United States of America. 92: 8130-4. PMID 7667257 DOI: 10.1073/Pnas.92.18.8130  0.695
1995 Lovich MA, Edelman ER. Mechanisms of transmural heparin transport in the rat abdominal aorta after local vascular delivery. Circulation Research. 77: 1143-50. PMID 7586227 DOI: 10.1161/01.Res.77.6.1143  0.364
1995 Edelman ER. Perivascular delivery of heparin regulates myointimal hyperplasia Reactive Polymers. 25: 149-156. DOI: 10.1016/0923-1137(95)00050-S  0.386
1995 Prausnitz MR, Edelman ER, Gimm JA, Langer R, Weaver JC. Transdermal delivery of heparin by skin electroporation Nature Biotechnology. 13: 1205-1209.  0.396
1994 Edelman ER, Karnovsky MJ. Contrasting effects of the intermittent and continuous administration of heparin in experimental restenosis. Circulation. 89: 770-6. PMID 8313565 DOI: 10.1161/01.Cir.89.2.770  0.556
1994 Sellke FW, Wang SY, Friedman M, Harada K, Edelman ER, Grossman W, Simons M. Basic FGF enhances endothelium-dependent relaxation of the collateral-perfused coronary microcirculation. The American Journal of Physiology. 267: H1303-11. PMID 7943375 DOI: 10.1152/Ajpheart.1994.267.4.H1303  0.345
1994 Simons M, Edelman ER, Rosenberg RD. Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimal hyperplasia in a rat carotid artery injury model. The Journal of Clinical Investigation. 93: 2351-6. PMID 7911126 DOI: 10.1172/Jci117240  0.32
1994 Harada K, Grossman W, Friedman M, Edelman ER, Prasad PV, Keighley CS, Manning WJ, Sellke FW, Simons M. Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts. The Journal of Clinical Investigation. 94: 623-30. PMID 7518840 DOI: 10.1172/Jci117378  0.304
1993 Edelman ER, Pukac LA, Karnovsky MJ. Protamine and protamine-insulins exacerbate the vascular response to injury. The Journal of Clinical Investigation. 91: 2308-13. PMID 8486791 DOI: 10.1172/Jci116460  0.547
1993 Edelman ER, Nugent MA, Karnovsky MJ. Perivascular and intravenous administration of basic fibroblast growth factor: vascular and solid organ deposition. Proceedings of the National Academy of Sciences of the United States of America. 90: 1513-7. PMID 8434012 DOI: 10.1073/Pnas.90.4.1513  0.737
1993 Edelman ER, Langer R. Optimization of release from magnetically controlled polymeric drug release devices. Biomaterials. 14: 621-6. PMID 8399957 DOI: 10.1016/0142-9612(93)90182-2  0.484
1993 Rogers C, Karnovsky MJ, Edelman ER. Inhibition of experimental neointimal hyperplasia and thrombosis depends on the type of vascular injury and the site of drug administration. Circulation. 88: 1215-21. PMID 8353883 DOI: 10.1161/01.Cir.88.3.1215  0.593
1993 Nugent MA, Karnovsky MJ, Edelman ER. Vascular cell-derived heparan sulfate shows coupled inhibition of basic fibroblast growth factor binding and mitogenesis in vascular smooth muscle cells. Circulation Research. 73: 1051-60. PMID 8222077 DOI: 10.1161/01.Res.73.6.1051  0.726
1992 Simons M, Edelman ER, DeKeyser JL, Langer R, Rosenberg RD. Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature. 359: 67-70. PMID 1522889 DOI: 10.1038/359067A0  0.52
1992 Edelman ER, Fiorino A, Grodzinsky A, Langer R. Mechanical deformation of polymer matrix controlled release devices modulates drug release. Journal of Biomedical Materials Research. 26: 1619-31. PMID 1484066 DOI: 10.1002/Jbm.820261207  0.488
1992 Nugent MA, Edelman ER. Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: a mechanism for cooperactivity. Biochemistry. 31: 8876-83. PMID 1390674 DOI: 10.1021/Bi00152A026  0.63
1992 Edelman ER, Nugent MA, Smith LT, Karnovsky MJ. Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries. The Journal of Clinical Investigation. 89: 465-73. PMID 1371124 DOI: 10.1172/Jci115607  0.741
1991 Edelman ER, Mathiowitz E, Langer R, Klagsbrun M. Controlled and modulated release of basic fibroblast growth factor. Biomaterials. 12: 619-26. PMID 1742404 DOI: 10.1016/0142-9612(91)90107-L  0.502
1991 Nugent MA, Chen OS, Edelman ER. Controlled Release of Fibroblast Growth Factor: Activity in Cell Culture Mrs Proceedings. 252. DOI: 10.1557/Proc-252-273  0.657
1990 Edelman ER, Adams DH, Karnovsky MJ. Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury. Proceedings of the National Academy of Sciences of the United States of America. 87: 3773-7. PMID 2339120 DOI: 10.1073/Pnas.87.10.3773  0.571
1989 Friedman PL, Selwyn AP, Edelman E, Wang PJ. Effect of selective intracoronary antiarrhythmic drug administration in sustained ventricular tachycardia. American Journal of Cardiology. 64: 475-480. PMID 2773791 DOI: 10.1016/0002-9149(89)90424-4  0.306
1987 Edelman ER, Brown L, Taylor J, Langer R. In vitro and in vivo kinetics of regulated drug release from polymer matrices by oscillating magnetic fields. Journal of Biomedical Materials Research. 21: 339-353. PMID 3558448 DOI: 10.1002/Jbm.820210307  0.487
1986 Brown L, Munoz C, Siemer L, Edelman E, Langer R. Controlled Release of Insulin From Polymer Matrices: Control of Diabetes in Rats Diabetes. 35: 692-697. PMID 3519324 DOI: 10.2337/Diab.35.6.692  0.462
1985 Edelman ER, Kost J, Bobeck H, Langer R. Regulation of drug release from polymer matrices by oscillating magnetic fields Journal of Biomedical Materials Research. 19: 67-83. PMID 4077873 DOI: 10.1002/Jbm.820190107  0.459
1985 Langer R, Brown L, Edelman E. [30] Controlled release and magnetically modulated release systems for macromolecules Methods in Enzymology. 112: 399-422. PMID 4046857 DOI: 10.1016/S0076-6879(85)12032-X  0.485
1985 Langer R, Siegel R, Brown L, Leong K, Kost J, Edelman E. Controlled release and magnetically modulated systems for macromolecular drugs. Annals of the New York Academy of Sciences. 446: 1-13. PMID 3893280 DOI: 10.1111/J.1749-6632.1985.Tb18386.X  0.663
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