| Year |
Citation |
Score |
| 2022 |
Barker CG, Petsalaki E, Giudice G, Sero J, Ekpenyong EN, Bakal C, Petsalaki E. Identification of phenotype-specific networks from paired gene expression-cell shape imaging data. Genome Research. 32: 750-765. PMID 35197309 DOI: 10.1101/gr.276059.121 |
0.328 |
|
| 2020 |
Hégarat N, Crncec A, Suarez Peredo Rodriguez MF, Echegaray Iturra F, Gu Y, Busby O, Lang PF, Barr AR, Bakal C, Kanemaki MT, Lamond AI, Novak B, Ly T, Hochegger H. Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B. The Embo Journal. e104419. PMID 32350921 DOI: 10.15252/Embj.2020104419 |
0.313 |
|
| 2020 |
Stojic L, Lun ATL, Mascalchi P, Ernst C, Redmond AM, Mangei J, Barr AR, Bousgouni V, Bakal C, Marioni JC, Odom DT, Gergely F. A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division. Nature Communications. 11: 1851. PMID 32296040 DOI: 10.1038/S41467-020-14978-7 |
0.421 |
|
| 2020 |
Müller PM, Rademacher J, Bagshaw RD, Wortmann C, Barth C, van Unen J, Alp KM, Giudice G, Eccles RL, Heinrich LE, Pascual-Vargas P, Sanchez-Castro M, Brandenburg L, Mbamalu G, Tucholska M, ... ... Bakal C, et al. Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions. Nature Cell Biology. PMID 32203420 DOI: 10.1038/S41556-020-0488-X |
0.39 |
|
| 2019 |
Peñalosa-Ruiz G, Bousgouni V, Gerlach JP, Waarlo S, van de Ven JV, Veenstra TE, Silva JCR, van Heeringen SJ, Bakal C, Mulder KW, Veenstra GJC. WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming. Stem Cell Reports. PMID 30880078 DOI: 10.1016/J.Stemcr.2019.02.006 |
0.345 |
|
| 2019 |
Hansel CS, Crowder SW, Cooper S, Gopal S, João Pardelha da Cruz M, de Oliveira Martins L, Keller D, Rothery S, Becce M, Cass AEG, Bakal C, Chiappini C, Stevens MM. Nanoneedle-Mediated Stimulation of Cell Mechanotransduction Machinery. Acs Nano. PMID 30829469 DOI: 10.1021/Acsnano.8B06998 |
0.402 |
|
| 2018 |
Spill F, Bakal C, Mak M. Mechanical and Systems Biology of Cancer. Computational and Structural Biotechnology Journal. 16: 237-245. PMID 30105089 DOI: 10.1016/J.Csbj.2018.07.002 |
0.358 |
|
| 2018 |
Heldt FS, Barr AR, Cooper S, Bakal C, Novák B. A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463760 DOI: 10.1073/Pnas.1715345115 |
0.349 |
|
| 2018 |
Sanchez-Alvarez M, Bakal C. PERK links the clock and protein stress in cancer. Nature Cell Biology. 20: 4-5. PMID 29269949 DOI: 10.1038/S41556-017-0019-6 |
0.332 |
|
| 2017 |
Sanchez-Alvarez M, Del Pozo MA, Bakal C. AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts. Scientific Reports. 7: 16497. PMID 29184100 DOI: 10.1038/S41598-017-16662-1 |
0.319 |
|
| 2017 |
Turner NC, Asghar U, Barr AR, Cutts R, Beaney M, Babina IS, Sampath D, Giltnane J, Lacap JA, Crocker L, Young A, Pearson A, Herrera-Abreu MT, Bakal C. Single-cell dynamics determines response to CDK4/6 inhibition in triple negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28606920 DOI: 10.1158/1078-0432.Ccr-17-0369 |
0.334 |
|
| 2017 |
Pascual-Vargas P, Cooper S, Sero J, Bousgouni V, Arias-Garcia M, Bakal C. RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer. Scientific Data. 4: 170018. PMID 28248929 DOI: 10.1038/Sdata.2017.18 |
0.42 |
|
| 2017 |
Cooper S, Bakal C. Accelerating Live Single-Cell Signalling Studies. Trends in Biotechnology. PMID 28161141 DOI: 10.1016/J.Tibtech.2017.01.002 |
0.386 |
|
| 2017 |
Sero JE, Bakal C. Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion. Cell Systems. PMID 28065575 DOI: 10.1016/J.Cels.2016.11.015 |
0.431 |
|
| 2017 |
Sailem HZ, Bakal C. Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics. Genome Research. 27: 196-207. PMID 27864353 DOI: 10.1101/Gr.202028.115 |
0.406 |
|
| 2017 |
Asghar U, Barr A, Cuts R, Beaney M, Babina I, Sampath D, Lacap J, Crocker L, Young A, Nerukar A, Pearson A, Herrera-Abreu M, Bakal C, Turner N. Abstract P5-04-01: Cell cycle dynamics at single cell level dictates response to CDK4/6 inhibition Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-04-01 |
0.357 |
|
| 2016 |
Barr AR, Heldt FS, Zhang T, Bakal C, Novák B. A Dynamical Framework for the All-or-None G1/S Transition. Cell Systems. 2: 27-37. PMID 27136687 DOI: 10.1016/J.Cels.2016.01.001 |
0.307 |
|
| 2016 |
Barr A, Heldt FS, Cooper S, Novak B, Bakal C. A single cell approach to understanding cell cycle entry in cancer European Journal of Cancer. 61. DOI: 10.1016/S0959-8049(16)61609-X |
0.348 |
|
| 2015 |
Sanchez-Alvarez M, Zhang Q, Finger F, Wakelam MJ, Bakal C. Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis. Open Biology. 5: 150093. PMID 26333836 DOI: 10.1098/Rsob.150093 |
0.349 |
|
| 2015 |
Cooper S, Sadok A, Bousgouni V, Bakal C. Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells. Molecular Biology of the Cell. PMID 26310441 DOI: 10.1091/Mbc.E15-06-0382 |
0.34 |
|
| 2015 |
Sero JE, Sailem HZ, Ardy RC, Almuttaqi H, Zhang T, Bakal C. Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells. Molecular Systems Biology. 11: 790. PMID 26148352 DOI: 10.15252/Msb.20145644 |
0.352 |
|
| 2015 |
Barr AR, Bakal C. A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Scientific Reports. 5: 10564. PMID 26037491 DOI: 10.1038/Srep10564 |
0.357 |
|
| 2014 |
Yin Z, Sailem H, Sero J, Ardy R, Wong ST, Bakal C. How cells explore shape space: a quantitative statistical perspective of cellular morphogenesis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 1195-203. PMID 25220035 DOI: 10.1002/Bies.201400011 |
0.393 |
|
| 2014 |
Sanchez-Alvarez M, Finger F, Arias-Garcia Mdel M, Bousgouni V, Pascual-Vargas P, Bakal C. Signaling networks converge on TORC1-SREBP activity to promote endoplasmic reticulum homeostasis. Plos One. 9: e101164. PMID 25007267 DOI: 10.1371/Journal.Pone.0101164 |
0.353 |
|
| 2014 |
Sailem H, Bousgouni V, Cooper S, Bakal C. Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity. Open Biology. 4: 130132. PMID 24451547 DOI: 10.1098/Rsob.130132 |
0.416 |
|
| 2013 |
Evans L, Sailem H, Vargas PP, Bakal C. Inferring signalling networks from images. Journal of Microscopy. 252: 1-7. PMID 23841886 DOI: 10.1111/Jmi.12062 |
0.333 |
|
| 2013 |
Yin Z, Sadok A, Sailem H, McCarthy A, Xia X, Li F, Garcia MA, Evans L, Barr AR, Perrimon N, Marshall CJ, Wong ST, Bakal C. A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nature Cell Biology. 15: 860-71. PMID 23748611 DOI: 10.1038/Ncb2764 |
0.54 |
|
| 2012 |
Garcia MA, Alvarez MS, Sailem H, Bousgouni V, Sero J, Bakal C. Differential RNAi screening provides insights into the rewiring of signalling networks during oxidative stress. Molecular Biosystems. 8: 2605-13. PMID 22790786 DOI: 10.1039/C2Mb25092F |
0.371 |
|
| 2012 |
Barr AR, Bakal C. A direct look at RNAi screens. Molecular Systems Biology. 8: 580. PMID 22531120 DOI: 10.1038/Msb.2012.14 |
0.337 |
|
| 2012 |
Meiri D, Marshall CB, Greeve MA, Kim B, Balan M, Suarez F, Bakal C, Wu C, Larose J, Fine N, Ikura M, Rottapel R. Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition. Molecular Cell. 45: 642-55. PMID 22405273 DOI: 10.1016/J.Molcel.2012.01.027 |
0.653 |
|
| 2011 |
Sero JE, Thodeti CK, Mammoto A, Bakal C, Thomas S, Ingber DE. Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. Plos One. 6: e28303. PMID 22194823 DOI: 10.1371/Journal.Pone.0028303 |
0.374 |
|
| 2011 |
Bakal C. Drosophila RNAi screening in a postgenomic world. Briefings in Functional Genomics. 10: 197-205. PMID 21752787 DOI: 10.1093/Bfgp/Elr015 |
0.379 |
|
| 2010 |
Bakal C, Perrimon N. Realizing the promise of RNAi high throughput screening. Developmental Cell. 18: 506-7. PMID 20412765 DOI: 10.1016/J.Devcel.2010.04.005 |
0.47 |
|
| 2010 |
Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annual Review of Biochemistry. 79: 37-64. PMID 20367032 DOI: 10.1146/Annurev-Biochem-060408-092949 |
0.521 |
|
| 2010 |
Nir O, Bakal C, Perrimon N, Berger B. Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. Genome Research. 20: 372-80. PMID 20144944 DOI: 10.1101/Gr.100248.109 |
0.539 |
|
| 2009 |
Griffin R, Sustar A, Bonvin M, Binari R, del Valle Rodriguez A, Hohl AM, Bateman JR, Villalta C, Heffern E, Grunwald D, Bakal C, Desplan C, Schubiger G, Wu CT, Perrimon N. The twin spot generator for differential Drosophila lineage analysis. Nature Methods. 6: 600-2. PMID 19633664 DOI: 10.1038/Nmeth.1349 |
0.506 |
|
| 2009 |
Kaplow IM, Singh R, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: automated detection of significant genes from functional genomic screens. Nature Methods. 6: 476-7. PMID 19564846 DOI: 10.1038/Nmeth0709-476 |
0.583 |
|
| 2008 |
Bakal C, Linding R, Llense F, Heffern E, Martin-Blanco E, Pawson T, Perrimon N. Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (New York, N.Y.). 322: 453-6. PMID 18927396 DOI: 10.1126/Science.1158739 |
0.526 |
|
| 2008 |
Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. Bmc Bioinformatics. 9: 264. PMID 18534020 DOI: 10.1186/1471-2105-9-264 |
0.506 |
|
| 2008 |
Baym M, Bakal C, Perrimon N, Berger B. High-resolution modeling of cellular signaling networks Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4955: 257-271. DOI: 10.1007/978-3-540-78839-3_22 |
0.386 |
|
| 2007 |
Bakal C, Aach J, Church G, Perrimon N. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science (New York, N.Y.). 316: 1753-6. PMID 17588932 DOI: 10.1126/Science.1140324 |
0.56 |
|
| 2007 |
Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong STC. Online phenotype discovery in high-content RNAi screens using gap statistics Aip Conference Proceedings. 952: 86-95. DOI: 10.1063/1.2816647 |
0.393 |
|
| 2005 |
Tsuchihara K, Lapin V, Bakal C, Okada H, Brown L, Hirota-Tsuchihara M, Zaugg K, Ho A, Itie-Youten A, Harris-Brandts M, Rottapel R, Richardson CD, Benchimol S, Mak TW. Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner. Cancer Research. 65: 6685-91. PMID 16061649 DOI: 10.1158/0008-5472.Can-04-4223 |
0.607 |
|
| 2005 |
Bakal CJ, Finan D, LaRose J, Wells CD, Gish G, Kulkarni S, DeSepulveda P, Wilde A, Rottapel R. The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 9529-34. PMID 15976019 DOI: 10.1073/Pnas.0504190102 |
0.577 |
|
| 2004 |
Hara H, Bakal C, Wada T, Bouchard D, Rottapel R, Saito T, Penninger JM. The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse. The Journal of Experimental Medicine. 200: 1167-77. PMID 15520247 DOI: 10.1084/Jem.20032246 |
0.588 |
|
| 2004 |
Okada H, Bakal C, Shahinian A, Elia A, Wakeham A, Suh WK, Duncan GS, Ciofani M, Rottapel R, Zúñiga-Pflücker JC, Mak TW. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. The Journal of Experimental Medicine. 199: 399-410. PMID 14757745 DOI: 10.1084/Jem.20032092 |
0.599 |
|
| 2003 |
Hara H, Wada T, Bakal C, Kozieradzki I, Suzuki S, Suzuki N, Nghiem M, Griffiths EK, Krawczyk C, Bauer B, D'Acquisto F, Ghosh S, Yeh WC, Baier G, Rottapel R, et al. The MAGUK family protein CARD11 is essential for lymphocyte activation. Immunity. 18: 763-75. PMID 12818158 DOI: 10.1016/S1074-7613(03)00148-1 |
0.576 |
|
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