Year |
Citation |
Score |
2022 |
Gao S, Zhang W, Barrow SL, Iavarone AT, Klinman JP. Temperature-dependent hydrogen deuterium exchange shows impact of analog binding on adenosine deaminase flexibility but not embedded thermal networks. The Journal of Biological Chemistry. 102350. PMID 35933011 DOI: 10.1016/j.jbc.2022.102350 |
0.545 |
|
2022 |
Gao S, Klinman JP. Functional roles of enzyme dynamics in accelerating active site chemistry: Emerging techniques and changing concepts. Current Opinion in Structural Biology. 75: 102434. PMID 35872562 DOI: 10.1016/j.sbi.2022.102434 |
0.538 |
|
2021 |
Gao S, Thompson EJ, Barrow SL, Zhang W, Iavarone AT, Klinman JP. Correction to "Hydrogen-Deuterium Exchange within Adenosine Deaminase, a TIM Barrel Hydrolase, Identifies Networks for Thermal Activation of Catalysis". Journal of the American Chemical Society. PMID 33570951 DOI: 10.1021/jacs.1c01046 |
0.649 |
|
2020 |
Gao S, Thompson EJ, Barrow SL, Zhang W, Iavarone AT, Klinman JP. Hydrogen-Deuterium Exchange within Adenosine Deaminase, a TIM Barrel Hydrolase, Identifies Networks for Thermal Activation of Catalysis. Journal of the American Chemical Society. PMID 33181018 DOI: 10.1021/jacs.0c07866 |
0.692 |
|
2020 |
Chen Y, Gao F, Zheng G, Gao S. Enantioselective synthesis of a chiral intermediate of himbacine analogs by Burkholderia cepacia lipase A. Biotechnology Letters. PMID 32691184 DOI: 10.1007/S10529-020-02969-Z |
0.634 |
|
2020 |
Zhang J, Balsbaugh JL, Gao S, Ahn NG, Klinman JP. Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol -methyltransferase reaction. Proceedings of the National Academy of Sciences of the United States of America. PMID 32371482 DOI: 10.1073/Pnas.1917219117 |
0.561 |
|
2019 |
Li H, Gao S, Qiu Y, Liang C, Zhu S, Zheng G. Genome mining integrating semi-rational protein engineering and nanoreactor design: roadmap for a robust biocatalyst for industrial resolution of Vince lactam. Applied Microbiology and Biotechnology. PMID 31828408 DOI: 10.1007/S00253-019-10275-6 |
0.663 |
|
2019 |
Shen X, Zhou D, Lin Y, Wang J, Gao S, Kandavelu P, Zhang H, Zhang R, Wang BC, Rose J, Yuan Q, Yan Y. Structural Insights into Catalytic Versatility of the Flavin-dependent Hydroxylase (HpaB) from Escherichia coli. Scientific Reports. 9: 7087. PMID 31068633 DOI: 10.1107/S0108767319095928 |
0.355 |
|
2019 |
Chen Y, Zhang X, Zheng G, Gao S. Preparation of the enantiomerically enriched precursor of lamivudine (3TC™) via asymmetric catalysis mediated by Klebsiella oxytoca Process Biochemistry. 81: 77-84. DOI: 10.1016/J.Procbio.2019.03.025 |
0.609 |
|
2018 |
Gao S, Lu Y, Li Y, Huang R, Zheng G. Enhancement in the catalytic activity of Sulfolobus solfataricus P2 (+)-γ-lactamase by semi-rational design with the aid of a newly established high-throughput screening method. Applied Microbiology and Biotechnology. PMID 30310965 DOI: 10.1007/S00253-018-9428-0 |
0.67 |
|
2018 |
Su Y, Gao S, Li H, Zheng G. Enantioselective resolution of γ-lactam utilizing a novel (+)-γ-lactamase from Bacillus thuringiensis Process Biochemistry. 72: 96-104. DOI: 10.1016/J.Procbio.2018.06.017 |
0.714 |
|
2017 |
Gao S, Zhu S, Huang R, Li H, Wang H, Zheng G. Engineering the enantioselectivity and thermostability of a (+)-γ-lactamase from Microbacterium hydrocarbonoxydans for the kinetic resolution of Vince lactam. Applied and Environmental Microbiology. PMID 29054871 DOI: 10.1128/Aem.01780-17 |
0.672 |
|
2017 |
Gao S, Zhou Y, Zhang W, Wang W, Yu Y, Mu Y, Wang H, Gong X, Zheng G, Feng Y. Structural insights into the γ-lactamase activity and substrate enantioselectivity of an isochorismatase-like hydrolase from Microbacterium hydrocarbonoxydans. Scientific Reports. 7: 44542. PMID 28295028 DOI: 10.1038/srep44542 |
0.66 |
|
2017 |
Gao S, Su Y, Zhao L, Li G, Zheng G. Characterization of a (R)-selective amine transaminase from Fusarium oxysporum Process Biochemistry. 63: 130-136. DOI: 10.1016/J.Procbio.2017.08.012 |
0.624 |
|
2016 |
Gao S, Huang R, Zhu S, Li H, Zheng G. Identification and characterization of a novel (+)-γ-lactamase from Microbacterium hydrocarbonoxydans. Applied Microbiology and Biotechnology. PMID 27255489 DOI: 10.1007/S00253-016-7643-0 |
0.697 |
|
2015 |
Zhu S, Huang R, Gao S, Li X, Zheng G. Discovery and characterization of a second extremely thermostable (+)-γ-lactamase from Sulfolobus solfataricus P2. Journal of Bioscience and Bioengineering. PMID 26685014 DOI: 10.1016/J.Jbiosc.2015.09.012 |
0.672 |
|
2015 |
Gao S, Zhu S, Huang R, Lu Y, Zheng G. Efficient synthesis of the intermediate of abacavir and carbovir using a novel (+)-γ-lactamase as a catalyst. Bioorganic & Medicinal Chemistry Letters. PMID 26235952 DOI: 10.1016/J.Bmcl.2015.07.054 |
0.69 |
|
2012 |
Zhu S, Gong C, Song D, Gao S, Zheng G. Discovery of a novel (+)-γ-lactamase from Bradyrhizobium japonicum USDA 6 by rational genome mining. Applied and Environmental Microbiology. 78: 7492-5. PMID 22885756 DOI: 10.1128/Aem.01398-12 |
0.609 |
|
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