Carl W. Cotman, PhD - Related publications

Affiliations: 
Neurology University of California, Irvine, Irvine, CA 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=18
Website:
http://www.faculty.uci.edu/profile.cfm?faculty_id=2273
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A. PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. Progress in Neurobiology. 101818. PMID 32380223 DOI: 10.1016/j.pneurobio.2020.101818   
2020 Yuan C, Aierken A, Xie Z, Li N, Zhao J, Qing H. The age-related microglial transformation in Alzheimer's disease pathogenesis. Neurobiology of Aging. 92: 82-91. PMID 32408056 DOI: 10.1016/j.neurobiolaging.2020.03.024   
2020 Vyas Y, Montgomery JM, Cheyne JE. Hippocampal Deficits in Amyloid-β-Related Rodent Models of Alzheimer's Disease. Frontiers in Neuroscience. 14: 266. PMID 32317913 DOI: 10.3389/fnins.2020.00266   
2020 Jiang R, Wu XF, Wang B, Guan RX, Lv LM, Li AP, Lei L, Ma Y, Li N, Li QF, Ma QH, Zhao J, Li S. Reduction of NgR in perforant path decreases amyloid-β peptide production and ameliorates synaptic and cognitive deficits in APP/PS1 mice. Alzheimer's Research & Therapy. 12: 47. PMID 32331528 DOI: 10.1186/s13195-020-00616-3   
2020 Yang WD, Dong WG. [Mechanisms of electroacupuncture for improving Alzheimer's disease from reducing β amyloid protein level]. Zhen Ci Yan Jiu = Acupuncture Research. 45: 426-31. PMID 32447861 DOI: 10.13702/j.1000-0607.180885   
2020 Ghosh S, Durgvanshi S, Agarwal S, Raghunath M, Sinha JK. Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer's disease. Current Neuropharmacology. PMID 32348223 DOI: 10.2174/1570159X18666200429011823   
2020 Gee MS, Son SH, Jeon SH, Do J, Kim N, Ju YJ, Lee SJ, Chung EK, Inn KS, Kim NJ, Lee JK. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimer's Research & Therapy. 12: 45. PMID 32317025 DOI: 10.1186/s13195-020-00617-2   
2020 Kou X, Chen D, Chen N. The Regulation of microRNAs in Alzheimer's Disease. Frontiers in Neurology. 11: 288. PMID 32362867 DOI: 10.3389/fneur.2020.00288   
2020 Park SY, Kang JY, Lee T, Nam D, Jeon CJ, Kim JB. Can Reduce Amyloid Beta and Reverse Cognitive Impairment and Memory Dysfunction in Alzheimer's Disease Mouse Model. Cells. 9. PMID 32455709 DOI: 10.3390/cells9051275   
2020 Ferreiro E, Lanzillo M, Canhoto D, Carvalho da Silva AM, Mota SI, Dias IS, Ferreira IL, Fontes AR, Mastrella G, Pinheiro P, Valero J, Rego AC. Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model. Neurobiology of Aging. 92: 98-113. PMID 32417750 DOI: 10.1016/j.neurobiolaging.2020.04.003   
2020 Angelopoulou E, Paudel YN, Shaikh MF, Piperi C. Flotillin: A Promising Biomarker for Alzheimer's Disease. Journal of Personalized Medicine. 10. PMID 32225073 DOI: 10.3390/jpm10020020   
2020 Lim KH, Joo JY. Predictive Potential of Circulating Ube2h mRNA as an E2 Ubiquitin-Conjugating Enzyme for Diagnosis or Treatment of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32403399 DOI: 10.3390/ijms21093398   
2020 Novak G, Streffer JR, Timmers M, Henley D, Brashear HR, Bogert J, Russu A, Janssens L, Tesseur I, Tritsmans L, Van Nueten L, Engelborghs S. Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study. Alzheimer's Research & Therapy. 12: 58. PMID 32410694 DOI: 10.1186/s13195-020-00614-5   
2020 Mullane K, Williams M. Alzheimer's disease beyond amyloid: can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery? Biochemical Pharmacology. 113945. PMID 32247851 DOI: 10.1016/j.bcp.2020.113945   
2020 Sultan S, Taimuri U, Basnan SA, Ai-Orabi WK, Awadallah A, Almowald F, Hazazi A. Low Vitamin D and Its Association with Cognitive Impairment and Dementia. Journal of Aging Research. 2020: 6097820. PMID 32399297 DOI: 10.1155/2020/6097820   
2020 Amponsah AE, Feng B, Guo R, Zhang W, He J, Kong D, Dong T, Ma J, Cui H. Fragmentation of brain apolipoprotein E (ApoE) and its relevance in Alzheimer's disease. Reviews in the Neurosciences. PMID 32364519 DOI: 10.1515/revneuro-2019-0115   
2020 Klementieva O, Sandt C, Martinsson I, Kansiz M, Gouras GK, Borondics F. Super-Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903004. PMID 32195099 DOI: 10.1002/advs.201903004   
2020 Gupta SP, Patil VM. Recent Studies on Design and Development of Drugs Against Alzheimer's Disease (AD) Based on Inhibition of BACE-1 and Other AD-causative Agents. Current Topics in Medicinal Chemistry. PMID 32297584 DOI: 10.2174/1568026620666200416091623   
2020 Kim TW, Park SS, Park JY, Park HS. Infusion of Plasma from Exercised Mice Ameliorates Cognitive Dysfunction by Increasing Hippocampal Neuroplasticity and Mitochondrial Functions in 3xTg-AD Mice. International Journal of Molecular Sciences. 21. PMID 32384696 DOI: 10.3390/ijms21093291   
2020 Song YY, Xu WT, Zhang XC, Ni GX. Mechanisms of Electroacupuncture on Alzheimer's Disease: A Review of Animal Studies. Chinese Journal of Integrative Medicine. PMID 32318906 DOI: 10.1007/s11655-020-3092-9   
2020 Quevenco FC, van Bergen JM, Treyer V, Studer ST, Kagerer SM, Meyer R, Gietl AF, Kaufmann PA, Nitsch RM, Hock C, Unschuld PG. Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4. Frontiers in Aging Neuroscience. 12: 46. PMID 32210782 DOI: 10.3389/fnagi.2020.00046   
2020 Uddin MS, Kabir MT, Mamun AA, Barreto GE, Rashid M, Perveen A, Ashraf GM. Pharmacological approaches to mitigate neuroinflammation in Alzheimer's disease. International Immunopharmacology. 84: 106479. PMID 32353686 DOI: 10.1016/j.intimp.2020.106479   
2020 Chen Y, Bian Y, Wang JW, Gong TT, Ying YM, Ma LF, Shan WG, Xie XQ, Zhan ZJ. Effects of α-Mangostin Derivatives on the Alzheimer's Disease Model of Rats and Their Mechanism: A Combination of Experimental Study and Computational Systems Pharmacology Analysis. Acs Omega. 5: 9846-9863. PMID 32391472 DOI: 10.1021/acsomega.0c00057   
2020 Eke CS, Jammeh E, Li X, Carroll C, Pearson S, Ifeachor E. Early Detection of Alzheimer's Disease with Blood Plasma Proteins using Support Vector Machines. Ieee Journal of Biomedical and Health Informatics. PMID 32340968 DOI: 10.1109/JBHI.2020.2984355   
2020 Ren P, Chen J, Li B, Zhang M, Yang B, Guo X, Chen Z, Cheng H, Wang P, Wang S, Wang N, Zhang G, Wu X, Ma D, Guan D, et al. Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress. Oxidative Medicine and Cellular Longevity. 2020: 3050971. PMID 32454936 DOI: 10.1155/2020/3050971   
2020 Leblhuber F, Steiner K, Geisler S, Fuchs D, Gostner JM. On the possible relevance of bottom-up pathways in the pathogenesis of Alzheimer's dementia. Current Topics in Medicinal Chemistry. PMID 32407280 DOI: 10.2174/1568026620666200514090359   
2020 Qin T, Prins S, Groeneveld GJ, Van Westen G, de Vries HE, Wong YC, Bischoff LJM, de Lange ECM. Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals. International Journal of Molecular Sciences. 21. PMID 32365768 DOI: 10.3390/ijms21093158   
2020 Xu XD, Teng Y, Zou JY, Ye Y, Song H, Wang ZY. Effects of lycopene on vascular remodeling through the LXR-PI3K-AKT signaling pathway in APP/PS1 mice. Biochemical and Biophysical Research Communications. PMID 32253029 DOI: 10.1016/j.bbrc.2020.02.063   
2020 Yang J, Wise L, Fukuchi KI. TLR4 Cross-Talk With NLRP3 Inflammasome and Complement Signaling Pathways in Alzheimer's Disease. Frontiers in Immunology. 11: 724. PMID 32391019 DOI: 10.3389/fimmu.2020.00724   
2020 Kim S, Nam Y, Kim C, Lee H, Hong S, Kim HS, Shin SJ, Park YH, Mai HN, Oh SM, Kim KS, Yoo DH, Chung WK, Chung H, Moon M. Neuroprotective and Anti-Inflammatory Effects of Low-Moderate Dose Ionizing Radiation in Models of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32456197 DOI: 10.3390/ijms21103678   
2020 Yang Y, Zhou J, Li J. Regulation of exosome for Alzheimer's disease derived from mesenchymal stem cells. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 45: 169-175. PMID 32386043 DOI: 10.11817/j.issn.1672-7347.2020.180779   
2020 Malpas CB, Sharmin S, Kalincik T. The histopathological staging of tau, but not amyloid, corresponds to antemortem cognitive status, dementia stage, functional abilities, and neuropsychiatric symptoms. The International Journal of Neuroscience. 1-13. PMID 32303140 DOI: 10.1080/00207454.2020.1758087   
2020 Maron R, Armony G, Tsoory M, Wilchek M, Frenkel D, Arnon R. Peptide Interference with APP and Tau Association: Relevance to Alzheimer's Disease Amelioration. International Journal of Molecular Sciences. 21. PMID 32380752 DOI: 10.3390/ijms21093270   
2020 Harris LD, Jasem S, Licchesi JDF. The Ubiquitin System in Alzheimer's Disease. Advances in Experimental Medicine and Biology. 1233: 195-221. PMID 32274758 DOI: 10.1007/978-3-030-38266-7_8   
2020 Tan YX, Liu GC, Chen HL, Lu MN, Chen B, Hu T, Zhang L, Mao R, Li S, Mei R, Wang XY, Xiyang YB. Exercise-Induced Cognitive Improvement Is Associated with Sodium Channel-Mediated Excitability in APP/PS1 Mice. Neural Plasticity. 2020: 9132720. PMID 32256560 DOI: 10.1155/2020/9132720   
2020 Zameer S, Alam M, Hussain S, Vohora D, Ali J, Akhtar M. Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet. Brain Research Bulletin. PMID 32389800 DOI: 10.1016/j.brainresbull.2020.04.010   
2020 Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I, Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y. Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32475008 DOI: 10.1096/fj.201902731RR   
2020 Muñoz P, Ardiles ÁO, Pérez B, Nuñez C, Paula-Lima A, González-Billault C, Espinosa-Parrilla Y. Redox modifications in synaptic components as biomarkers of cognitive status, in brain aging and disease. Mechanisms of Ageing and Development. 111250. PMID 32433996 DOI: 10.1016/j.mad.2020.111250   
2020 Cho HJ, Sharma AK, Zhang Y, Gross ML, Mirica LM. A Multifunctional Chemical Agent as an Attenuator of Amyloid Burden and Neuroinflammation in Alzheimer's Disease. Acs Chemical Neuroscience. PMID 32310630 DOI: 10.1021/acschemneuro.0c00114   
2020 Barthet G, Mulle C. Presynaptic failure in Alzheimer's disease. Progress in Neurobiology. 101801. PMID 32428558 DOI: 10.1016/j.pneurobio.2020.101801   
2020 Sperling RA, Donohue MC, Raman R, Sun CK, Yaari R, Holdridge K, Siemers E, Johnson KA, Aisen PS, . Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals. Jama Neurology. PMID 32250387 DOI: 10.1001/jamaneurol.2020.0387   
2020 Deng L, Haynes PA, Wu Y, Amirkhani A, Kamath KS, Wu JX, Pushpitha K, Gupta V, Graham S, Gupta VK, Mirzaei M. Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions. Neural Regeneration Research. 15: 2131-2142. PMID 32394972 DOI: 10.4103/1673-5374.282261   
2020 Deng X, Zhao S, Liu X, Han L, Wang R, Hao H, Jiao Y, Han S, Bai C. : a source for anti-Alzheimer's disease drugs. Pharmaceutical Biology. 58: 410-416. PMID 32429787 DOI: 10.1080/13880209.2020.1758732   
2020 Kaeser GE, Chun J. Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer's Disease. Frontiers in Genetics. 11: 390. PMID 32457796 DOI: 10.3389/fgene.2020.00390   
2020 Andrade V, Cortés N, Pastor G, Gonzalez A, Ramos-Escobar N, Pastene E, Rojo LE, Maccioni RB. N-Acetyl Cysteine and Catechin-Derived Polyphenols: A Path Toward Multi-Target Compounds Against Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32390631 DOI: 10.3233/JAD-200067   
2020 Risacher SL, WuDunn D, Tallman EF, West JD, Gao S, Farlow MR, Brosch JR, Apostolova LG, Saykin AJ. Visual contrast sensitivity is associated with the presence of cerebral amyloid and tau deposition. Brain Communications. 2: fcaa019. PMID 32309804 DOI: 10.1093/braincomms/fcaa019   
2020 Chen SY, Gao Y, Sun JY, Meng XL, Yang D, Fan LH, Xiang L, Wang P. Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer's Disease. Frontiers in Pharmacology. 11: 497. PMID 32390843 DOI: 10.3389/fphar.2020.00497   
2020 Flores-Muñoz C, Gómez B, Mery E, Mujica P, Gajardo I, Córdova C, Lopez-Espíndola D, Durán-Aniotz C, Hetz C, Muñoz P, Gonzalez-Jamett AM, Ardiles ÁO. Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer's Disease. Frontiers in Cellular Neuroscience. 14: 46. PMID 32265655 DOI: 10.3389/fncel.2020.00046   
2020 Husna Ibrahim N, Yahaya MF, Mohamed W, Teoh SL, Hui CK, Kumar J. Pharmacotherapy of Alzheimer's Disease: Seeking Clarity in a Time of Uncertainty. Frontiers in Pharmacology. 11: 261. PMID 32265696 DOI: 10.3389/fphar.2020.00261   
2020 Singh RK. Antagonism of cysteinyl leukotrienes and their receptors as a neuroinflammatory target in Alzheimer's disease. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. PMID 32281039 DOI: 10.1007/s10072-020-04369-7