Randall Bateman - Publications

Affiliations: 
Neurology Washington University School of Medicine, St. Louis, MO, United States 

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Bateman RJ, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/s41380-019-0404-6  0.48
2019 Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, ... ... Bateman RJ, et al. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30897203 DOI: 10.1093/brain/awz050  0.48
2019 Su Y, Flores S, Wang G, Hornbeck RC, Speidel B, Joseph-Mathurin N, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Jack CR, Farlow MR, Salloway S, Snider BJ, Berman SB, ... ... Bateman RJ, et al. Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 180-190. PMID 30847382 DOI: 10.1016/j.dadm.2018.12.008  0.48
2019 Schindler SE, Li Y, Todd KW, Herries EM, Henson RL, Gray JD, Wang G, Graham DL, Shaw LM, Trojanowski JQ, Hassenstab JJ, Benzinger TLS, Cruchaga C, Jucker M, Levin J, ... ... Bateman RJ, et al. Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30846386 DOI: 10.1016/j.jalz.2018.12.019  0.48
2019 Wang G, Coble D, McDade EM, Hassenstab J, Fagan AM, Benzinger TLS, Bateman RJ, Morris JC, Xiong C. Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30773445 DOI: 10.1016/j.jalz.2018.12.008  0.48
2019 Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, ... ... Bateman RJ, et al. Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers. Brain : a Journal of Neurology. PMID 30753379 DOI: 10.1093/brain/awz019  0.48
2019 Goyal MS, Blazey TM, Su Y, Couture LE, Durbin TJ, Bateman RJ, Benzinger TL, Morris JC, Raichle ME, Vlassenko AG. Persistent metabolic youth in the aging female brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718410 DOI: 10.1073/pnas.1815917116  0.48
2019 Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, ... ... Bateman RJ, et al. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease. Nature Medicine. PMID 30664784 DOI: 10.1038/s41591-018-0304-3  0.48
2018 Vöglein J, Noachtar S, McDade E, Quaid KA, Salloway S, Ghetti B, Noble J, Berman S, Chhatwal J, Mori H, Fox N, Allegri R, Masters CL, Buckles V, Ringman JM, ... ... Bateman RJ, et al. Seizures as an early symptom of autosomal dominant Alzheimer's disease. Neurobiology of Aging. 76: 18-23. PMID 30616208 DOI: 10.1016/j.neurobiolaging.2018.11.022  0.48
2018 Wang G, Xiong C, McDade EM, Hassenstab J, Aschenbrenner AJ, Fagan AM, Benzinger TLS, Gordon BA, Morris JC, Li Y, Bateman RJ. Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 4: 669-676. PMID 30569014 DOI: 10.1016/j.trci.2018.10.009  0.48
2018 Bussy A, Snider BJ, Coble D, Xiong C, Fagan AM, Cruchaga C, Benzinger TLS, Gordon BA, Hassenstab J, Bateman RJ, Morris JC. Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network. Neurobiology of Aging. 75: 42-50. PMID 30530186 DOI: 10.1016/j.neurobiolaging.2018.10.011  0.48
2018 Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. Embo Molecular Medicine. PMID 30482868 DOI: 10.15252/emmm.201809712  0.48
2018 Twohig D, Rodriguez-Vieitez E, Sando SB, Berge G, Lauridsen C, Møller I, Grøntvedt GR, Bråthen G, Patra K, Bu G, Benzinger TLS, Karch CM, Fagan A, Morris JC, Bateman RJ, et al. The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease. Acta Neuropathologica Communications. 6: 130. PMID 30477568 DOI: 10.1186/s40478-018-0624-z  0.48
2018 Joseph-Mathurin N, Su Y, Blazey TM, Jasielec M, Vlassenko A, Friedrichsen K, Gordon BA, Hornbeck RC, Cash L, Ances BM, Veale T, Cash DM, Brickman AM, Buckles V, Cairns NJ, ... ... Bateman RJ, et al. Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 669-677. PMID 30417072 DOI: 10.1016/j.dadm.2018.08.012  0.48
2018 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Fox NN, Graff-Radford NR, Levin J, Danek A, ... ... Bateman RJ, et al. Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30266303 DOI: 10.1016/j.jalz.2018.06.3059  0.48
2018 Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, et al. White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30239611 DOI: 10.1093/brain/awy229  0.48
2018 McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, ... ... Bateman RJ, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/WNL.0000000000006277  0.48
2018 Karch CM, Hernández D, Wang JC, Marsh J, Hewitt AW, Hsu S, Norton J, Levitch D, Donahue T, Sigurdson W, Ghetti B, Farlow M, Chhatwal J, Berman S, Cruchaga C, ... ... Bateman RJ, et al. Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. Alzheimer's Research & Therapy. 10: 69. PMID 30045758 DOI: 10.1186/s13195-018-0400-0  0.48
2018 Hsu S, Gordon BA, Hornbeck R, Norton JB, Levitch D, Louden A, Ziegemeier E, Laforce R, Chhatwal J, Day GS, McDade E, Morris JC, Fagan AM, Benzinger TLS, Goate AM, ... ... Bateman RJ, et al. Discovery and validation of autosomal dominant Alzheimer's disease mutations. Alzheimer's Research & Therapy. 10: 67. PMID 30021643 DOI: 10.1186/s13195-018-0392-9  0.48
2018 Lim YY, Hassenstab J, Goate A, Fagan AM, Benzinger TLS, Cruchaga C, McDade E, Chhatwal J, Levin J, Farlow MR, Graff-Radford NR, Laske C, Masters CL, Salloway S, Schofield P, ... ... Bateman RJ, et al. Effect of BDNFVal66Met on disease markers in dominantly inherited AD. Annals of Neurology. PMID 30014553 DOI: 10.1002/ana.25299  0.48
2018 Li Z, Del-Aguila JL, Dube U, Budde J, Martinez R, Black K, Xiao Q, Cairns NJ, Dougherty JD, Lee JM, Morris JC, Bateman RJ, Karch CM, Cruchaga C, et al. Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure. Genome Medicine. 10: 43. PMID 29880032 DOI: 10.1186/s13073-018-0551-4  0.48
2018 Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, ... ... Bateman RJ, et al. Tau Kinetics in Neurons and the Human Central Nervous System. Neuron. 98: 861-864. PMID 29772204 DOI: 10.1016/j.neuron.2018.04.035  0.56
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Bateman RJ, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/journal.pone.0195838  0.48
2018 Wildburger NC, Gyngard F, Guillermier C, Patterson BW, Elbert D, Mawuenyega KG, Schneider T, Green K, Roth R, Schmidt RE, Cairns NJ, Benzinger TLS, Steinhauser ML, Bateman RJ. Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracerand Exhibit Nanoscale Heterogeneity. Frontiers in Neurology. 9: 169. PMID 29623063 DOI: 10.3389/fneur.2018.00169  0.4
2018 Oxtoby NP, Young AL, Cash DM, Benzinger TLS, Fagan AM, Morris JC, Bateman RJ, Fox NC, Schott JM, Alexander DC. Data-driven models of dominantly-inherited Alzheimer's disease progression. Brain : a Journal of Neurology. PMID 29579160 DOI: 10.1093/brain/awy050  0.48
2018 Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, ... ... Bateman RJ, et al. Tau Kinetics in Neurons and the Human Central Nervous System. Neuron. 97: 1284-1298.e7. PMID 29566794 DOI: 10.1016/j.neuron.2018.02.015  0.56
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... ... Bateman R, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/brain/awy053  0.48
2018 Villeneuve S, Vogel JW, Gonneaud J, Pichet Binette A, Rosa-Neto P, Gauthier S, Bateman RJ, Fagan AM, Morris JC, Benzinger TLS, Johnson SC, Breitner JCS, Poirier J. Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease. Jama Neurology. PMID 29482212 DOI: 10.1001/jamaneurol.2017.5135  0.48
2018 Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Bateman RJ, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/brain/awy008  0.48
2018 Lucey BP, Hicks TJ, Elbert DL, Ovod V, Mawuenyega KG, Morris JC, Bateman RJ. Reply to "Excess amyloid beta can be degraded in healthy humans". Annals of Neurology. PMID 29457845 DOI: 10.1002/ana.25185  0.48
2018 Gordon BA, Blazey TM, Su Y, Hari-Raj A, Dincer A, Flores S, Christensen J, McDade E, Wang G, Xiong C, Cairns NJ, Hassenstab J, Marcus DS, Fagan AM, Jack CR, ... ... Bateman RJ, et al. Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. The Lancet. Neurology. PMID 29397305 DOI: 10.1016/S1474-4422(18)30028-0  0.48
2017 Xiong C, Luo J, Morris JC, Bateman R. Linear Combinations of Multiple Outcome Measures to Improve the Power of Efficacy Analysis ---Application to Clinical Trials on Early Stage Alzheimer Disease. Biostatistics & Epidemiology. 1: 36-58. PMID 29546251 DOI: 10.1080/24709360.2017.1331821  0.48
2017 Weng H, Bateman R, Morris JC, Xiong C. Validity and power of minimization algorithm in longitudinal analysis of clinical trials. Biostatistics & Epidemiology. 1: 59-77. PMID 29250611 DOI: 10.1080/24709360.2017.1331822  0.48
2017 Lucey BP, Hicks TJ, McLeland JS, Toedebusch CD, Boyd J, Elbert DL, Patterson BW, Baty J, Morris JC, Ovod V, Mawuenyega KG, Bateman RJ. Effect of sleep on overnight CSF amyloid-β kinetics. Annals of Neurology. PMID 29220873 DOI: 10.1002/ana.25117  0.48
2017 Xiong C, Luo J, Chen L, Gao F, Liu J, Wang G, Bateman R, Morris JC. Estimating diagnostic accuracy for clustered ordinal diagnostic groups in the three-class case-Application to the early diagnosis of Alzheimer disease. Statistical Methods in Medical Research. 962280217742539. PMID 29182052 DOI: 10.1177/0962280217742539  0.48
2017 Yoon H, Belmonte KC, Kasten T, Bateman R, Kim J. Intra- and Inter-individual Variability of microRNA Levels in Human Cerebrospinal Fluid: Critical Implications for Biomarker Discovery. Scientific Reports. 7: 12720. PMID 28983117 DOI: 10.1038/s41598-017-13031-w  0.56
2017 Cruchaga C, Del-Aguila JL, Saef B, Black K, Fernandez MV, Budde J, Ibanez L, Kapoor M, Tosto G, Mayeux RP, Holtzman DM, Fagan AM, Morris JC, Bateman RJ, Goate AM, et al. Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28943286 DOI: 10.1016/j.jalz.2017.08.013  0.48
2017 Wildburger NC, Esparza TJ, LeDuc RD, Fellers RT, Thomas PM, Cairns NJ, Kelleher NL, Bateman RJ, Brody DL. Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. Scientific Reports. 7: 9520. PMID 28842697 DOI: 10.1038/s41598-017-10422-x  0.36
2017 Goyal MS, Vlassenko AG, Blazey TM, Su Y, Couture LE, Durbin TJ, Bateman RJ, Benzinger TL, Morris JC, Raichle ME. Loss of Brain Aerobic Glycolysis in Normal Human Aging. Cell Metabolism. 26: 353-360.e3. PMID 28768174 DOI: 10.1016/j.cmet.2017.07.010  0.48
2017 Ringman JM, Casado M, Van Berlo V, Pa J, Joseph-Mathurin N, Fagan AM, Benzinger T, Bateman RJ, Morris JC. A novel PSEN1 (S230N) mutation causing early-onset Alzheimer's Disease associated with prosopagnosia, hoarding, and Parkinsonism. Neuroscience Letters. 657: 11-15. PMID 28764909 DOI: 10.1016/j.neulet.2017.07.046  0.48
2017 Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/j.jalz.2017.06.2268  0.48
2017 Ovod V, Ramsey KN, Mawuenyega KG, Bollinger JG, Hicks T, Schneider T, Sullivan M, Paumier K, Holtzman DM, Morris JC, Benzinger T, Fagan AM, Patterson BW, Bateman RJ. Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28734653 DOI: 10.1016/j.jalz.2017.06.2266  0.48
2017 Brown BM, Sohrabi HR, Taddei K, Gardener SL, Rainey-Smith SR, Peiffer JJ, Xiong C, Fagan AM, Benzinger T, Buckles V, Erickson KI, Clarnette R, Shah T, Masters CL, Weiner M, ... ... Bateman RJ, et al. Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28501451 DOI: 10.1016/j.jalz.2017.03.008  0.48
2017 Lucey BP, Fagan AM, Holtzman DM, Morris JC, Bateman RJ. Diurnal oscillation of CSF Aβ and other AD biomarkers. Molecular Neurodegeneration. 12: 36. PMID 28478762 DOI: 10.1186/s13024-017-0161-4  0.48
2017 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Dietzsch J, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Graff-Radford NR, Levin J, Galasko D, ... ... Bateman RJ, et al. Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease. Scientific Reports. 7: 1225. PMID 28450713 DOI: 10.1038/s41598-017-01327-w  0.48
2017 Schoenfeld HA, West T, Verghese PB, Holubasch M, Shenoy N, Kagan D, Buono C, Zhou W, DeCristofaro M, Douville J, Goodrich GG, Mansfield K, Saravanan C, Cumin F, Webb RL, ... Bateman RJ, et al. The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey. Toxicology and Applied Pharmacology. PMID 28315356 DOI: 10.1016/j.taap.2017.03.014  0.4
2016 Ghosal K, Haag M, Verghese PB, West T, Veenstra T, Braunstein JB, Bateman RJ, Holtzman DM, Landreth GE. A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects. Alzheimer's & Dementia (New York, N. Y.). 2: 110-120. PMID 29067298 DOI: 10.1016/j.trci.2016.06.001  0.48
2016 Lucey BP, Mawuenyega KG, Patterson BW, Elbert DL, Ovod V, Kasten T, Morris JC, Bateman RJ. Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System. Jama Neurology. PMID 27992627 DOI: 10.1001/jamaneurol.2016.4202  0.56
2016 Suárez-Calvet M, Araque Caballero MÁ, Kleinberger G, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Ewers M, Haass C. Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury. Science Translational Medicine. 8: 369ra178. PMID 27974666 DOI: 10.1126/scitranslmed.aag1767  0.48
2016 Esparza TJ, Wildburger NC, Jiang H, Gangolli M, Cairns NJ, Bateman RJ, Brody DL. Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains. Scientific Reports. 6: 38187. PMID 27917876 DOI: 10.1038/srep38187  0.4
2016 Baker-Nigh AT, Mawuenyega KG, Bollinger JG, Ovod V, Kasten T, Franklin EE, Liao F, Jiang H, Holtzman D, Cairns NJ, Morris JC, Bateman RJ. Human Central Nervous System (CNS) ApoE Isoforms are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared to Plasma. The Journal of Biological Chemistry. PMID 27793990 DOI: 10.1074/jbc.M116.721779  0.56
2016 Natelson Love M, Clark DG, Cochran JN, Den Beste KA, Geldmacher DS, Benzinger TL, Gordon BA, Morris JC, Bateman RJ, Roberson ED. Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease. Neurobiology of Aging. PMID 27793474 DOI: 10.1016/j.neurobiolaging.2016.09.020  0.48
2016 Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, ... ... Bateman RJ, et al. Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). The Lancet. Neurology. PMID 27777020 DOI: 10.1016/S1474-4422(16)30229-0  0.48
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Bateman RJ, et al. Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0163669. PMID 27649320 DOI: 10.1371/journal.pone.0163669  0.48
2016 Bateman RJ, Benzinger TL, Berry S, Clifford DB, Duggan C, Fagan AM, Fanning K, Farlow MR, Hassenstab J, McDade EM, Mills S, Paumier K, Quintana M, Salloway SP, Santacruz A, et al. The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27583651 DOI: 10.1016/j.jalz.2016.07.005  0.48
2016 Lim YY, Hassenstab J, Cruchaga C, Goate A, Fagan AM, Benzinger TL, Maruff P, Snyder PJ, Masters CL, Allegri R, Chhatwal J, Farlow MR, Graff-Radford NR, Laske C, Levin J, ... ... Bateman RJ, et al. BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 27521573 DOI: 10.1093/brain/aww200  0.44
2016 Muenchhoff J, Poljak A, Thalamuthu A, Gupta VB, Chatterjee P, Raftery M, Masters CL, Morris JC, Bateman RJ, Fagan AM, Martins RN, Sachdev PS. Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease. Scientific Reports. 6: 29078. PMID 27381087 DOI: 10.1038/srep29078  0.44
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Bateman RJ, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647  0.48
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Bateman RJ, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/journal.pone.0152082  0.48
2016 Hölttä M, Dean RA, Siemers E, Mawuenyega KG, Sigurdson W, May PC, Holtzman DM, Portelius E, Zetterberg H, Bateman RJ, Blennow K, Gobom J. A single dose of the γ-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in humans. Alzheimer's Research & Therapy. 8: 11. PMID 26948580 DOI: 10.1186/s13195-016-0178-x  0.44
2016 Chatterjee P, Lim WL, Shui G, Gupta VB, James I, Fagan AM, Xiong C, Sohrabi HR, Taddei K, Brown BM, Benzinger T, Masters C, Snowden SG, Wenk MR, Bateman RJ, et al. Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 26836186 DOI: 10.3233/JAD-150948  0.48
2015 Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/nrneurol.2015.177  0.48
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, ... ... Bateman RJ, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/WNL.0000000000001903  0.44
2015 Lucey BP, Gonzales C, Das U, Li J, Siemers ER, Slemmon JR, Bateman RJ, Huang Y, Fox GB, Claassen JA, Slats D, Verbeek MM, Tong G, Soares H, Savage MJ, et al. An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter. Alzheimer's Research & Therapy. 7: 53. PMID 26225140 DOI: 10.1186/s13195-015-0136-z  0.44
2015 Grill JD, Bateman RJ, Buckles V, Oliver A, Morris JC, Masters CL, Klunk WE, Ringman JM. A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 7: 50. PMID 26203303 DOI: 10.1186/s13195-015-0135-0  0.48
2015 Bateman RJ, Morris JC. Factors Contributing to the Post-Lumbar Puncture Headache—Reply. Jama Neurology. 72: 835. PMID 26167902 DOI: 10.1001/jamaneurol.2015.0691  0.44
2015 Crisp MJ, Mawuenyega KG, Patterson BW, Reddy NC, Chott R, Self WK, Weihl CC, Jockel-Balsarotti J, Varadhachary AS, Bucelli RC, Yarasheski KE, Bateman RJ, Miller TM. In vivo kinetic approach reveals slow SOD1 turnover in the CNS. The Journal of Clinical Investigation. 125: 2772-80. PMID 26075819 DOI: 10.1172/JCI80705  0.44
2015 Patterson BW, Elbert DL, Mawuenyega KG, Kasten T, Ovod V, Ma S, Xiong C, Chott R, Yarasheski K, Sigurdson W, Zhang L, Goate A, Benzinger T, Morris JC, Holtzman D, ... Bateman RJ, et al. Age and amyloid effects on human CNS amyloid-beta kinetics. Annals of Neurology. PMID 26040676 DOI: 10.1002/ana.24454  0.44
2015 Cairns NJ, Perrin RJ, Franklin EE, Carter D, Vincent B, Xie M, Bateman RJ, Benzinger T, Friedrichsen K, Brooks WS, Halliday GM, McLean C, Ghetti B, Morris JC, et al. Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN). Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 25964057 DOI: 10.1111/neup.12205  0.44
2015 Laske C, Sohrabi HR, Jasielec MS, Müller S, Koehler NK, Gräber S, Förster S, Drzezga A, Mueller-Sarnowski F, Danek A, Jucker M, Bateman RJ, Buckles V, Saykin AJ, Martins RN, et al. Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study. Biomed Research International. 2015: 828120. PMID 25922840 DOI: 10.1155/2015/828120  0.44
2015 Ringman JM, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, ... ... Bateman R, et al. Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network. Brain : a Journal of Neurology. 138: 1036-45. PMID 25688083 DOI: 10.1093/brain/awv004  0.44
2015 Chatterjee P, Gupta VB, Fagan AM, Jasielec MS, Xiong C, Sohrabi HR, Dhaliwal S, Taddei K, Bourgeat P, Brown BM, Benzinger T, Bateman RJ, Morris JC, Martins RN. Decreased platelet APP isoform ratios in autosomal dominant Alzheimer's disease: baseline data from a DIAN cohort subset. Current Alzheimer Research. 12: 157-64. PMID 25654503  0.48
2015 Monserrate AE, Ryman DC, Ma S, Xiong C, Noble JM, Ringman JM, Morris JC, Danek A, Müller-Sarnowski F, Clifford DB, McDade EM, Brooks WS, Darby DG, Masters CL, Weston PS, ... ... Bateman RJ, et al. Factors associated with the onset and persistence of post-lumbar puncture headache. Jama Neurology. 72: 325-32. PMID 25622095 DOI: 10.1001/jamaneurol.2014.3974  0.44
2015 Elbert DL, Patterson BW, Bateman RJ. Analysis of a compartmental model of amyloid beta production, irreversible loss and exchange in humans. Mathematical Biosciences. 261: 48-61. PMID 25497960 DOI: 10.1016/j.mbs.2014.11.004  0.4
2015 Bateman R. Alzheimer's disease and other dementias: Advances in 2014 The Lancet Neurology. 14: 4-6. PMID 25496880 DOI: 10.1016/S1474-4422(14)70301-1  0.44
2015 Su Y, Blazey TM, Snyder AZ, Raichle ME, Marcus DS, Ances BM, Bateman RJ, Cairns NJ, Aldea P, Cash L, Christensen JJ, Friedrichsen K, Hornbeck RC, Farrar AM, Owen CJ, et al. Partial volume correction in quantitative amyloid imaging. Neuroimage. 107: 55-64. PMID 25485714 DOI: 10.1016/j.neuroimage.2014.11.058  0.44
2014 Sheline YI, West T, Yarasheski K, Jasielec MS, Hettinger JC, Tripoli DL, Xiong C, Frederiksen C, Grzelak MV, Bateman RJ, Morris JC, Lee JM, Cirrito JR. Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice". Science Translational Medicine. 6: 268lr4. PMID 25540323 DOI: 10.1126/scitranslmed.3010609  0.44
2014 Roberts KF, Elbert DL, Kasten TP, Patterson BW, Sigurdson WC, Connors RE, Ovod V, Munsell LY, Mawuenyega KG, Miller-Thomas MM, Moran CJ, Cross DT, Derdeyn CP, Bateman RJ. Amyloid-β efflux from the central nervous system into the plasma. Annals of Neurology. 76: 837-44. PMID 25205593 DOI: 10.1002/ana.24270  0.44
2014 Sieber BA, Landis S, Koroshetz W, Bateman R, Siderowf A, Galpern WR, Dunlop J, Finkbeiner S, Sutherland M, Wang H, Lee VM, Orr HT, Gwinn K, Ludwig K, Taylor A, et al. Prioritized research recommendations from the National Institute of Neurological Disorders and Stroke Parkinson's Disease 2014 conference. Annals of Neurology. 76: 469-72. PMID 25164235 DOI: 10.1002/ana.24261  0.44
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/jamaneurol.2014.1654  0.44
2014 Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, ... ... Bateman RJ, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/WNL.0000000000000596  0.44
2014 Dobrowolska JA, Michener MS, Wu G, Patterson BW, Chott R, Ovod V, Pyatkivskyy Y, Wildsmith KR, Kasten T, Mathers P, Dancho M, Lennox C, Smith BE, Gilberto D, McLoughlin D, ... ... Bateman RJ, et al. CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8336-46. PMID 24920637 DOI: 10.1523/JNEUROSCI.0540-14.2014  0.44
2014 Lucey BP, Bateman RJ. Amyloid-β diurnal pattern: Possible role of sleep in Alzheimer's disease pathogenesis Neurobiology of Aging. 35. PMID 24910393 DOI: 10.1016/j.neurobiolaging.2014.03.035  0.44
2014 Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, DeKosky ST, Gauthier S, Selkoe D, Bateman R, Cappa S, Crutch S, Engelborghs S, Frisoni GB, Fox NC, et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. The Lancet. Neurology. 13: 614-29. PMID 24849862 DOI: 10.1016/S1474-4422(14)70090-0  0.44
2014 Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, et al. An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice. Science Translational Medicine. 6: 236re4. PMID 24828079 DOI: 10.1126/scitranslmed.3008169  0.44
2014 Wardlaw SL, Burant CF, Klein S, Meece K, White A, Kasten T, Lucey BP, Bateman RJ. Continuous 24-hour leptin, proopiomelanocortin, and amino acid measurements in human cerebrospinal fluid: correlations with plasma leptin, soluble leptin receptor, and amino acid levels. The Journal of Clinical Endocrinology and Metabolism. 99: 2540-8. PMID 24670082 DOI: 10.1210/jc.2013-4087  0.56
2014 Dobrowolska JA, Kasten T, Huang Y, Benzinger TL, Sigurdson W, Ovod V, Morris JC, Bateman RJ. Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system. Plos One. 9: e89998. PMID 24646516 DOI: 10.1371/journal.pone.0089998  0.44
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/scitranslmed.3007901  0.44
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/pnas.1317918110  0.44
2013 Moulder KL, Snider BJ, Mills SL, Buckles VD, Santacruz AM, Bateman RJ, Morris JC. Dominantly Inherited Alzheimer Network: facilitating research and clinical trials. Alzheimer's Research & Therapy. 5: 48. PMID 24131566 DOI: 10.1186/alzrt213  0.44
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... ... Bateman RJ, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/WNL.0b013e3182a841c6  0.44
2013 Frost SM, Kanagasingam Y, Sohrabi HR, Taddei K, Bateman R, Morris J, Benzinger T, Goate A, Masters CL, Martins RN. Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers. Current Alzheimer Research. 10: 790-6. PMID 23919771 DOI: 10.2174/15672050113109990154  0.44
2013 Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, ... ... Bateman R, et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 81: 736-44. PMID 23884042 DOI: 10.1212/WNL.0b013e3182a1aafe  0.44
2013 Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ. Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers. Science Translational Medicine. 5: 189ra77. PMID 23761040 DOI: 10.1126/scitranslmed.3005615  0.44
2013 Mawuenyega KG, Kasten T, Sigurdson W, Bateman RJ. Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics. Analytical Biochemistry. 440: 56-62. PMID 23714261 DOI: 10.1016/j.ab.2013.04.031  0.56
2013 Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL. Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls. Annals of Neurology. 73: 104-19. PMID 23225543 DOI: 10.1002/ana.23748  0.44
2012 Huang Y, Potter R, Sigurdson W, Kasten T, Connors R, Morris JC, Benzinger T, Mintun M, Ashwood T, Ferm M, Budd SL, Bateman RJ. β-amyloid dynamics in human plasma. Archives of Neurology. 69: 1591-7. PMID 23229043 DOI: 10.1001/archneurol.2012.18107  0.56
2012 Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/cli.12.93  0.48
2012 Roh JH, Huang Y, Bero AW, Kasten T, Stewart FR, Bateman RJ, Holtzman DM. Disruption of the sleep-wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer's disease pathology. Science Translational Medicine. 4: 150ra122. PMID 22956200 DOI: 10.1126/scitranslmed.3004291  0.44
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/NEJMoa1202753  0.44
2012 Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, ... ... Bateman RJ, et al. In vivo human apolipoprotein E isoform fractional turnover rates in the CNS. Plos One. 7: e38013. PMID 22675504 DOI: 10.1371/journal.pone.0038013  0.44
2012 Hata S, Taniguchi M, Piao Y, Ikeuchi T, Fagan AM, Holtzman DM, Bateman R, Sohrabi HR, Martins RN, Gandy S, Urakami K, Suzuki T. Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects. Molecular Neurodegeneration. 7: 16. PMID 22534039 DOI: 10.1186/1750-1326-7-16  0.44
2012 Portelius E, Zetterberg H, Dean RA, Marcil A, Bourgeois P, Nutu M, Andreasson U, Siemers E, Mawuenyega KG, Sigurdson WC, May PC, Paul SM, Holtzman DM, Blennow K, Bateman RJ. Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 335-41. PMID 22531418 DOI: 10.3233/JAD-2012-120508  0.44
2012 Basak JM, Kim J, Pyatkivskyy Y, Wildsmith KR, Jiang H, Parsadanian M, Patterson BW, Bateman RJ, Holtzman DM. Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling. Molecular Neurodegeneration. 7: 14. PMID 22512932 DOI: 10.1186/1750-1326-7-14  0.44
2012 Ovod V, Scott EA, Flake MM, Parker SR, Bateman RJ, Elbert DL. Exposure of the lysine in the gamma chain dodecapeptide of human fibrinogen is not enhanced by adsorption to poly(ethylene terephthalate) as measured by biotinylation and mass spectrometry. Journal of Biomedical Materials Research. Part A. 100: 622-31. PMID 22213354 DOI: 10.1002/jbm.a.33285  0.44
2012 Rajagopal R, Bateman R, Van Stavern GP. Visual involvement in corticobasal syndrome. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 32: 338-40. PMID 21926916 DOI: 10.1097/WNO.0b013e3182305162  0.44
2012 Huang Y, Potter R, Sigurdson W, Santacruz A, Shih S, Ju YE, Kasten T, Morris JC, Mintun M, Duntley S, Bateman RJ. Effects of age and amyloid deposition on Aβ dynamics in the human central nervous system. Archives of Neurology. 69: 51-8. PMID 21911660 DOI: 10.1001/archneurol.2011.235  0.56
2011 Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Science Translational Medicine. 3: 89ra57. PMID 21715678 DOI: 10.1126/scitranslmed.3002156  0.44
2011 Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, ... ... Bateman R, et al. Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction. Annals of Neurology. 69: 1026-31. PMID 21681798 DOI: 10.1002/ana.22343  0.44
2011 Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman JM, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimer's Research & Therapy. 3: 1. PMID 21211070 DOI: 10.1186/alzrt59  0.44
2010 Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science (New York, N.Y.). 330: 1774. PMID 21148344 DOI: 10.1126/science.1197623  0.56
2010 Cook JJ, Wildsmith KR, Gilberto DB, Holahan MA, Kinney GG, Mathers PD, Michener MS, Price EA, Shearman MS, Simon AJ, Wang JX, Wu G, Yarasheski KE, Bateman RJ. Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6743-50. PMID 20463236 DOI: 10.1523/JNEUROSCI.1381-10.2010  0.44
2009 Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science (New York, N.Y.). 326: 1005-7. PMID 19779148 DOI: 10.1126/science.1180962  0.44
2009 Wildsmith KR, Han B, Bateman RJ. Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry. Analytical Biochemistry. 395: 116-8. PMID 19653990 DOI: 10.1016/j.ab.2009.07.049  0.4
2009 Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system. Annals of Neurology. 66: 48-54. PMID 19360898 DOI: 10.1002/ana.21623  0.44
2008 Elbert DL, Mawuenyega KG, Scott EA, Wildsmith KR, Bateman RJ. Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scans. Journal of Proteome Research. 7: 4546-56. PMID 18774841 DOI: 10.1021/pr800386u  0.44
2008 Bateman RJ, Klunk WE. Measuring Target Effect of Proposed Disease-Modifying Therapies in Alzheimer's Disease Neurotherapeutics. 5: 381-390. PMID 18625449 DOI: 10.1016/j.nurt.2008.05.009  0.44
2007 Bateman RJ, Munsell LY, Chen X, Holtzman DM, Yarasheski KE. Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. Journal of the American Society For Mass Spectrometry. 18: 997-1006. PMID 17383190 DOI: 10.1016/j.jasms.2007.02.009  0.48
2007 Bateman RJ, Wen G, Morris JC, Holtzman DM. Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker. Neurology. 68: 666-9. PMID 17325273 DOI: 10.1212/01.wnl.0000256043.50901.e3  0.48
2007 Bateman RJ, Eidelberg D. Testing a test for Alzheimer disease Neurology. 68: 482-483. PMID 17296912 DOI: 10.1212/01.wnl.0000257671.88772.f1  0.44
2006 Yin KJ, Cirrito JR, Yan P, Hu X, Xiao Q, Pan X, Bateman R, Song H, Hsu FF, Turk J, Xu J, Hsu CY, Mills JC, Holtzman DM, Lee JM. Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10939-48. PMID 17065436 DOI: 10.1523/JNEUROSCI.2085-06.2006  0.44
2006 Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nature Medicine. 12: 856-61. PMID 16799555 DOI: 10.1038/nm1438  0.48
2006 Yan P, Hu X, Song H, Yin K, Bateman RJ, Cirrito JR, Xiao Q, Hsu FF, Turk JW, Xu J, Hsu CY, Holtzman DM, Lee JM. Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ. The Journal of Biological Chemistry. 281: 24566-74. PMID 16787929 DOI: 10.1074/jbc.M602440200  0.44
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