Kazuhisa Sekimizu - Publications

Affiliations: 
Department of Pharmacy Tokyo University, Minato-ku, Tōkyō-to, Japan 

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kaito C, Yoshikai H, Wakamatsu A, Miyashita A, Matsumoto Y, Fujiyuki T, Kato M, Ogura Y, Hayashi T, Isogai T, Sekimizu K. Non-pathogenic Escherichia coli acquires virulence by mutating a growth-essential LPS transporter. Plos Pathogens. 16: e1008469. PMID 32324807 DOI: 10.1371/journal.ppat.1008469  0.56
2020 Matsumoto Y, Takahashi M, Sekimizu K. Polysaccharides of a fermented food, natto, suppress sucrose-induced hyperglycemia in an in vivo evaluation system and inhibit glucose uptake by human intestinal cells. Drug Discoveries & Therapeutics. 14: 8-13. PMID 32147629 DOI: 10.5582/ddt.2020.01002  0.56
2020 Paudel A, Hamamoto H, Panthee S, Matsumoto Y, Sekimizu K. Large-scale screening and identification of novel pathogenic Staphylococcus aureus genes using a silkworm infection model. The Journal of Infectious Diseases. PMID 31912866 DOI: 10.1093/infdis/jiaa004  0.6
2019 Matsumoto Y, Ishii M, Hasegawa S, Sekimizu K. Enterococcus faecalis YM0831 suppresses sucrose-induced hyperglycemia in a silkworm model and in humans. Communications Biology. 2: 157. PMID 31925042 DOI: 10.1038/s42003-019-0407-5  0.56
2019 Matsumoto Y, Takahashi M, Umehara M, Asano M, Maruki-Uchida H, Morita M, Sekimizu K. Suppressive effects of whey protein hydrolysate on sucrose-induced hyperglycemia in silkworms. Drug Discoveries & Therapeutics. PMID 31611487 DOI: 10.5582/ddt.2019.01069  0.56
2019 Mitsutomi S, Akimitsu N, Sekimizu K, Kaito C. Identification of 2H phosphoesterase superfamily proteins with 2´-CPDase activity. Biochimie. PMID 31422053 DOI: 10.1016/j.biochi.2019.08.008  0.52
2019 Panthee S, Paudel A, Blom J, Hamamoto H, Sekimizu K. Complete Genome Sequence of 0916-4-2 and Its Comparative Genomic Analysis. Frontiers in Microbiology. 10: 1619. PMID 31396169 DOI: 10.3389/fmicb.2019.01619  0.6
2019 Ishii M, Matsumoto Y, Katada T, Sekimizu K. Additive effects of Kothala himbutu (Salacia reticulata) extract and a lactic acid bacterium (Enterococcus faecalis YM0831) for suppression of sucrose-induced hyperglycemia in an in vivo silkworm evaluation system. Drug Discoveries & Therapeutics. 13: 133-136. PMID 31327788 DOI: 10.5582/ddt.2019.01025  0.56
2019 Itoh H, Tokumoto K, Kaji T, Paudel A, Panthee S, Hamamoto H, Sekimizu K, Inoue M. Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E. Nature Communications. 10: 2992. PMID 31278250 DOI: 10.1038/s41467-019-10754-4  0.6
2019 Hamamoto H, Horie R, Sekimizu K. Pharmacokinetics of anti-infectious reagents in silkworms. Scientific Reports. 9: 9451. PMID 31263251 DOI: 10.1038/s41598-019-46013-1  0.6
2019 Nwibo DD, Panthee S, Hamamoto H, Sekimizu K. Molecular characterization of multi-drug resistant coagulase negative cocci in non-hospital environment. Drug Discoveries & Therapeutics. PMID 31231110 DOI: 10.5582/ddt.2019.01031  0.6
2019 Ryuno H, Nigo F, Naguro I, Sekimizu K, Kaito C. Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph. Plos One. 14: e0217517. PMID 31145754 DOI: 10.1371/journal.pone.0217517  0.52
2019 Matsumoto Y, Ishii M, Hasegawa S, Sekimizu K. YM0831 suppresses sucrose-induced hyperglycemia in a silkworm model and in humans. Communications Biology. 2: 157. PMID 31069266 DOI: 10.1038/s42003-019-0407-5  0.56
2019 Matsumoto Y, Sekimizu K. Silkworm as an experimental animal for research on fungal infections. Microbiology and Immunology. PMID 30666711 DOI: 10.1111/1348-0421.12668  0.56
2018 Nakajima H, Matsumoto Y, Sekimizu K. Establishment of a gnotobiotic silkworm model. Drug Discoveries & Therapeutics. 12: 291-294. PMID 30464160 DOI: 10.5582/ddt.2018.01048  0.56
2018 Ishii M, Matsumoto Y, Sekimizu K. Bacterial polysaccharides inhibit sucrose-induced hyperglycemia in silkworms. Drug Discoveries & Therapeutics. 12: 185-188. PMID 30146618 DOI: 10.5582/ddt.2018.01040  0.56
2018 Panthee S, Hamamoto H, Ishijima SA, Paudel A, Sekimizu K. Utilization of hybrid assembly approach to determine the genome of an opportunistic pathogenic fungus, Candida albicans TIMM 1768. Genome Biology and Evolution. PMID 30059981 DOI: 10.1093/gbe/evy166  0.6
2018 Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, et al. Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis. Cell Death & Disease. 9: 797. PMID 30038238 DOI: 10.1038/s41419-018-0815-3  0.6
2018 Ishii M, Matsumoto Y, Sekimizu K. Inhibitory effects of alpha-cyclodextrin and its derivative against sucrose-induced hyperglycemia in an in vivo evaluation system. Drug Discoveries & Therapeutics. 12: 122-125. PMID 29998992 DOI: 10.5582/ddt.2018.01028  0.56
2018 Hamamoto H, Sekimizu K. [Development of Antibiotics Using Silkworm Bacteria and Fungi Infection Model]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 138: 895-899. PMID 29962465 DOI: 10.1248/yakushi.17-00202-4  0.6
2018 Ishii M, Matsumoto Y, Sekimizu K. Estimation of lactic acid bacterial cell number by DNA quantification. Drug Discoveries & Therapeutics. 12: 88-91. PMID 29760341 DOI: 10.5582/ddt.2018.01019  0.56
2018 Paudel A, Panthee S, Urai M, Hamamoto H, Ohwada T, Sekimizu K. Pharmacokinetic parameters explain the therapeutic activity of antimicrobial agents in a silkworm infection model. Scientific Reports. 8: 1578. PMID 29371643 DOI: 10.1038/s41598-018-19867-0  0.6
2017 Matsumoto Y, Ishii M, Shimizu K, Kawamoto S, Sekimizu K. [A Silkworm Infection Model to Evaluate Antifungal Drugs for Cryptococcosis]. Medical Mycology Journal. 58: E131-E137. PMID 29187715 DOI: 10.3314/mmj.17.016  0.56
2017 Mitsutomi S, Sekimizu K, Kaito C. Isolation of antibiotic-producing Pseudomonas species with low-temperature cultivation of temperate soil. Drug Discoveries & Therapeutics. 11: 267-275. PMID 29081439 DOI: 10.5582/ddt.2017.01053  0.52
2017 Kochi Y, Matsumoto Y, Sekimizu K, Kaito C. Two-spotted cricket as an animal infection model of human pathogenic fungi. Drug Discoveries & Therapeutics. PMID 29081438 DOI: 10.5582/ddt.2017.01052  0.56
2017 Urai M, Aizawa T, Imamura K, Hamamoto H, Sekimizu K. Characterization of the chemical structure and innate immune-stimulating activity of an extracellular polysaccharide from Rhizobium sp. strain M2 screened using a silkworm muscle contraction assay. Drug Discoveries & Therapeutics. 11: 238-245. PMID 29021503 DOI: 10.5582/ddt.2017.01045  0.6
2017 Itoh H, Tokumoto K, Kaji T, Paudel A, Panthee S, Hamamoto H, Sekimizu K, Inoue M. Total Synthesis and Biological Mode of Action of WAP-8294A2: A Menaquinone-Targeting Antibiotic. The Journal of Organic Chemistry. PMID 29019678 DOI: 10.1021/acs.joc.7b02318  0.6
2017 Ishii M, Matsumoto Y, Yamada T, Abe S, Sekimizu K. An invertebrate infection model for evaluating anti-fungal agents against dermatophytosis. Scientific Reports. 7: 12289. PMID 28947778 DOI: 10.1038/s41598-017-12523-z  0.56
2017 Inoue M, Fujino H, Nagatomo M, Paudel A, Panthee S, Hamamoto H, Sekimizu K. Unified Total Synthesis of Polyoxin J, L, and Their Fluorinated Analogues Based on Decarbonylative Radical Coupling Reactions. Angewandte Chemie (International Ed. in English). PMID 28727238 DOI: 10.1002/anie.201706671  0.6
2017 Tabuchi F, Matsumoto Y, Ishii M, Tatsuno K, Okazaki M, Sato T, Moriya K, Sekimizu K. D-cycloserine increases the effectiveness of vancomycin against vancomycin-highly resistant Staphylococcus aureus. The Journal of Antibiotics. PMID 28588223 DOI: 10.1038/ja.2017.56  0.56
2017 Panthee S, Paudel A, Hamamoto H, Sekimizu K. Draft Genome Sequence of the Vancomycin-Resistant Clinical Isolate Staphylococcus aureus VRS3b. Genome Announcements. 5. PMID 28572324 DOI: 10.1128/genomeA.00452-17  0.6
2017 Paudel A, Hamamoto H, Panthee S, Kaneko K, Matsunaga S, Kanai M, Suzuki Y, Sekimizu K. A Novel Spiro-Heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in Staphylococcus aureus. Frontiers in Microbiology. 8: 712. PMID 28487682 DOI: 10.3389/fmicb.2017.00712  0.6
2017 Panthee S, Hamamoto H, Paudel A, Sekimizu K. Genomic analysis of vancomycin-resistant Staphylococcus aureus VRS3b and its comparison with other VRSA isolates. Drug Discoveries & Therapeutics. PMID 28458299 DOI: 10.5582/ddt.2017.01024  0.6
2017 Anantaworasakul P, Hamamoto H, Sekimizu K, Okonogi S. Biological activities and antibacterial biomarker of Sesbania grandiflora bark extract. Drug Discoveries & Therapeutics. 11: 70-77. PMID 28458298 DOI: 10.5582/ddt.2017.01013  0.6
2017 Kheawfu K, Pikulkaew S, Hamamoto H, Sekimizu K, Okonogi S. Influence of clove oil and eugenol on muscle contraction of silkworm (Bombyx mori). Drug Discoveries & Therapeutics. PMID 28458297 DOI: 10.5582/ddt.2017.01012  0.6
2017 Yagi A, Uchida R, Hamamoto H, Sekimizu K, Kimura KI, Tomoda H. Anti-Mycobacterium activity of microbial peptides in a silkworm infection model with Mycobacterium smegmatis. The Journal of Antibiotics. 70: 685-690. PMID 28446822 DOI: 10.1038/ja.2017.23  0.6
2017 Hamamoto H, Sekimizu K. Development of Novel Antibiotic Lysocin E Identified by Silkworm Infection Model. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 137: 389-392. PMID 28381711 DOI: 10.1248/yakushi.16-00235-4  0.6
2017 Nishida S, Ishii M, Nishiyama Y, Abe S, Ono Y, Sekimizu K. Lactobacillus paraplantarum 11-1 Isolated from Rice Bran Pickles Activated Innate Immunity and Improved Survival in a Silkworm Bacterial Infection Model. Frontiers in Microbiology. 8: 436. PMID 28373863 DOI: 10.3389/fmicb.2017.00436  0.56
2017 Panthee S, Paudel A, Hamamoto H, Sekimizu K. Advantages of the Silkworm As an Animal Model for Developing Novel Antimicrobial Agents. Frontiers in Microbiology. 8: 373. PMID 28326075 DOI: 10.3389/fmicb.2017.00373  0.6
2017 Anantaworasakul P, Hamamoto H, Sekimizu K, Okonogi S. In vitro antibacterial activity and in vivo therapeutic effect of Sesbania grandiflora in bacterial infected silkworms. Pharmaceutical Biology. 55: 1256-1262. PMID 28253823 DOI: 10.1080/13880209.2017.1297467  0.6
2017 Ishii M, Matsumoto Y, Nakamura I, Sekimizu K. Silkworm fungal infection model for identification of virulence genes in pathogenic fungus and screening of novel antifungal drugs. Drug Discoveries & Therapeutics. PMID 28228617 DOI: 10.5582/ddt.2016.01080  0.56
2017 Ishii M, Matsumoto Y, Nishida S, Sekimizu K. Decreased sugar concentration in vegetable and fruit juices by growth of functional lactic acid bacteria. Drug Discoveries & Therapeutics. PMID 28202883 DOI: 10.5582/ddt.2016.01079  0.56
2017 Ishii M, Nishida S, Kataoka K, Nishiyama Y, Abe S, Sekimizu K. Lactic acid bacteria of the Leuconostoc genus with high innate immunity-stimulating activity. Drug Discoveries & Therapeutics. PMID 28202882 DOI: 10.5582/ddt.2016.01078  0.56
2017 Tabuchi F, Matsumoto Y, Ishii M, Tatsuno K, Okazaki M, Sato T, Moriya K, Sekimizu K. Synergistic effects of vancomycin and β-lactams against vancomycin highly resistant Staphylococcus aureus. The Journal of Antibiotics. PMID 28196977 DOI: 10.1038/ja.2017.7  0.56
2017 Panthee S, Hamamoto H, Suzuki Y, Sekimizu K. In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5. The Journal of Antibiotics. 70: 204-207. PMID 27553855 DOI: 10.1038/ja.2016.102  0.6
2016 Yamamoto M, Kashimoto T, Yoshimura Y, Tachibana N, Kuroda S, Miki Y, Kitabayashi S, Tong P, Xiao J, Tanaka K, Hamamoto H, Sekimizu K, Yamamoto K. A silkworm infection model to investigate Vibrio vulnificus virulence genes. Molecular Medicine Reports. PMID 27748924 DOI: 10.3892/mmr.2016.5782  0.6
2016 Kaji T, Murai M, Itoh H, Yasukawa J, Hamamoto H, Sekimizu K, Inoue M. Total Synthesis and Functional Evaluation of Fourteen Derivatives of Lysocin E: Importance of Cationic, Hydrophobic, and Aromatic Moieties for Antibacterial Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27739191 DOI: 10.1002/chem.201604022  0.6
2016 Kizaki H, Omae Y, Tabuchi F, Saito Y, Sekimizu K, Kaito C. Cell-Surface Phenol Soluble Modulins Regulate Staphylococcus aureus Colony Spreading. Plos One. 11: e0164523. PMID 27723838 DOI: 10.1371/journal.pone.0164523  0.52
2016 Inagaki Y, Matsumoto Y, Tang W, Sekimizu K. Dividing phase-dependent cytotoxicity profiling of human embryonic lung fibroblast identifies candidate anticancer reagents. Drug Discoveries & Therapeutics. 10: 195-200. PMID 27594296 DOI: 10.5582/ddt.2016.01049  0.56
2016 Nakamura I, Kanasaki R, Yoshikawa K, Furukawa S, Fujie A, Hamamoto H, Sekimizu K. Discovery of a new antifungal agent ASP2397 using a silkworm model of Aspergillus fumigatus infection. The Journal of Antibiotics. PMID 27577982 DOI: 10.1038/ja.2016.106  0.6
2016 Panthee S, Hamamoto H, Paudel A, Sekimizu K. Lysobacter species: a potential source of novel antibiotics. Archives of Microbiology. PMID 27541998 DOI: 10.1007/s00203-016-1278-5  0.6
2016 Paudel A, Hamamoto H, Panthee S, Sekimizu K. Menaquinone as a potential target of antibacterial agents. Drug Discoveries & Therapeutics. 10: 123-8. PMID 27431268 DOI: 10.5582/ddt.2016.01041  0.6
2016 Imae K, Saito Y, Kizaki H, Ryuno H, Mao H, Miyashita A, Suzuki Y, Sekimizu K, Kaito C. Novel nucleoside diphosphatase contributes to Staphylococcus aureus virulence. The Journal of Biological Chemistry. PMID 27422825 DOI: 10.1074/jbc.M116.721845  0.52
2016 Kochi Y, Miyashita A, Tsuchiya K, Mitsuyama M, Sekimizu K, Kaito C. A human pathogenic bacterial infection model using the two-spotted cricket, Gryllus bimaculatus. Fems Microbiology Letters. 363. PMID 27377894 DOI: 10.1093/femsle/fnw163  0.52
2016 Matsumoto Y, Ishii M, Sekimizu K. An in vivo invertebrate evaluation system for identifying substances that suppress sucrose-induced postprandial hyperglycemia. Scientific Reports. 6: 26354. PMID 27194587 DOI: 10.1038/srep26354  0.56
2016 Miyashita A, Kizaki H, Sekimizu K, Kaito C. Body-enlarging effect of royal jelly in a non-holometabolous insect species, Gryllus bimaculatus. Biology Open. 5: 770-6. PMID 27185266 DOI: 10.1242/bio.019190  0.52
2016 Usui K, Nishida S, Sugita T, Ueki T, Matsumoto Y, Okumura H, Sekimizu K. Acute oral toxicity test of chemical compounds in silkworms. Drug Discoveries & Therapeutics. 10: 57-61. PMID 26971557 DOI: 10.5582/ddt.2016.01025  0.56
2016 Inagaki Y, Matsumoto Y, Sekimizu K. Using silkworms to establish alternative animal models for evaluation of drug-induced tissue injury. Drug Discoveries & Therapeutics. 10: 40-3. PMID 26971554 DOI: 10.5582/ddt.2016.01023  0.56
2016 Sekimizu K, Hamamoto H. Using silkworms as a laboratory animal to evaluate medicines and foods. Drug Discoveries & Therapeutics. 10: 1-2. PMID 26971551 DOI: 10.5582/ddt.2016.01018  0.6
2016 Matsumoto Y, Yasukawa J, Ishii M, Hayashi Y, Miyazaki S, Sekimizu K. A critical role of mevalonate for peptidoglycan synthesis in Staphylococcus aureus. Scientific Reports. 6: 22894. PMID 26961421 DOI: 10.1038/srep22894  0.56
2016 Matsumoto Y, Sekimizu K. Evaluation of anti-diabetic drugs by using silkworm, Bombyx mori. Drug Discoveries & Therapeutics. 10: 19-23. PMID 26961328 DOI: 10.5582/ddt.2016.01017  0.56
2016 Hamamoto H, Sekimizu K. Identification of lysocin E using a silkworm model of bacterial infection. Drug Discoveries & Therapeutics. 10: 24-9. PMID 26911796 DOI: 10.5582/ddt.2016.01012  0.6
2016 Matsumoto Y, Sekimizu K. A hyperglycemic silkworm model for evaluating hypoglycemic activity of Rehmanniae Radix, an herbal medicine. Drug Discoveries & Therapeutics. 10: 14-8. PMID 26902904 DOI: 10.5582/ddt.2016.01016  0.56
2016 Ishii M, Matsumoto Y, Sekimizu K. Usefulness of silkworm as a host animal for understanding pathogenicity of Cryptococcus neoformans. Drug Discoveries & Therapeutics. 10: 9-13. PMID 26902902 DOI: 10.5582/ddt.2016.01015  0.56
2016 Miyashita A, Kizaki H, Sekimizu K, Kaito C. No Effect of Body Size on the Frequency of Calling and Courtship Song in the Two-Spotted Cricket, Gryllus bimaculatus. Plos One. 11: e0146999. PMID 26785351 DOI: 10.1371/journal.pone.0146999  0.52
2015 Ishii K, Tabuchi F, Matsuo M, Tatsuno K, Sato T, Okazaki M, Hamamoto H, Matsumoto Y, Kaito C, Aoyagi T, Hiramatsu K, Kaku M, Moriya K, Sekimizu K. Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro mutagenesis. Scientific Reports. 5: 17092. PMID 26603341 DOI: 10.1038/srep17092  0.52
2015 Kyuma T, Kizaki H, Ryuno H, Sekimizu K, Kaito C. 16S rRNA methyltransferase KsgA contributes to oxidative stress resistance and virulence in Staphylococcus aureus. Biochimie. 119: 166-74. PMID 26545800 DOI: 10.1016/j.biochi.2015.10.027  0.52
2015 Ishii M, Matsumoto Y, Sekimizu K. Usefulness of silkworm as a model animal for understanding the molecular mechanisms of fungal pathogenicity. Drug Discoveries & Therapeutics. 9: 234-7. PMID 26370522 DOI: 10.5582/ddt.2015.01052  0.56
2015 Nwibo DD, Matsumoto Y, Sekimizu K. Identification and methods for prevention of Enterococcus mundtii infection in silkworm larvae, Bombyx mori, reared on artificial diet. Drug Discoveries & Therapeutics. 9: 184-90. PMID 26193940 DOI: 10.5582/ddt.2015.01036  0.56
2015 Ishii M, Matsumoto Y, Sekimizu K. Compounds in a particular production lot of tryptic soy broth inhibit Staphylococcus aureus cell growth. Drug Discoveries & Therapeutics. 9: 178-83. PMID 26193939 DOI: 10.5582/ddt.2015.01030  0.52
2015 Yoshikai H, Kizaki H, Saito Y, Omae Y, Sekimizu K, Kaito C. Multidrug-resistance transporter AbcA secretes Staphylococcus aureus cytolytic toxins. The Journal of Infectious Diseases. PMID 26160745 DOI: 10.1093/infdis/jiv376  0.52
2015 Miyashita A, Takahashi S, Ishii K, Sekimizu K, Kaito C. Primed Immune Responses Triggered by Ingested Bacteria Lead to Systemic Infection Tolerance in Silkworms. Plos One. 10: e0130486. PMID 26107254 DOI: 10.1371/journal.pone.0130486  0.6
2015 Inagaki Y, Matsumoto Y, Ishii M, Uchino K, Sezutsu H, Sekimizu K. Fluorescence imaging for a noninvasive in vivo toxicity-test using a transgenic silkworm expressing green fluorescent protein. Scientific Reports. 5: 11180. PMID 26061948 DOI: 10.1038/srep11180  0.52
2015 Matsumoto Y, Ishii M, Hayashi Y, Miyazaki S, Sugita T, Sumiya E, Sekimizu K. Diabetic silkworms for evaluation of therapeutically effective drugs against type II diabetes. Scientific Reports. 5: 10722. PMID 26024298 DOI: 10.1038/srep10722  0.52
2015 Nwibo DD, Hamamoto H, Matsumoto Y, Kaito C, Sekimizu K. Current use of silkworm larvae (Bombyx mori) as an animal model in pharmaco-medical research. Drug Discoveries & Therapeutics. 9: 133-5. PMID 25994065 DOI: 10.5582/ddt.2015.01026  0.6
2015 Su J, Iehara M, Yasukawa J, Matsumoto Y, Hamamoto H, Sekimizu K. A novel mutation in the vraS gene of Staphylococcus aureus contributes to reduce susceptibility against daptomycin. The Journal of Antibiotics. PMID 25899124 DOI: 10.1038/ja.2015.42  0.52
2015 Kyuma T, Kimura S, Hanada Y, Suzuki T, Sekimizu K, Kaito C. Ribosomal RNA methyltransferases contribute to Staphylococcus aureus virulence. The Febs Journal. 282: 2570-84. PMID 25893373 DOI: 10.1111/febs.13302  0.52
2015 Ishii K, Hamamoto H, Sekimizu K. Studies of host-pathogen interactions and immune-related drug development using the silkworm: interdisciplinary immunology, microbiology, and pharmacology studies. Drug Discoveries & Therapeutics. 9: 238-46. PMID 25865526 DOI: 10.5582/ddt.2015.01015  0.6
2015 Adachi T, Matsumoto Y, Inagaki Y, Sekimizu K. Niemann-Pick disease type C2 protein induces autophagy and inhibits growth in FM3A breast cancer cells. Drug Discoveries & Therapeutics. 9: 282-8. PMID 25843701 DOI: 10.5582/ddt.2015.01014  0.6
2015 Miyashita A, Hirai Y, Sekimizu K, Kaito C. Antibiotic-producing bacteria from stag beetle mycangia. Drug Discoveries & Therapeutics. 9: 33-7. PMID 25639488 DOI: 10.5582/ddt.2015.01000  0.52
2015 Ishii K, Hamamoto H, Sekimizu K. Paralytic peptide: an insect cytokine that mediates innate immunity. Archives of Insect Biochemistry and Physiology. 88: 18-30. PMID 25521626 DOI: 10.1002/arch.21215  0.6
2015 Mao J, Kuranaga T, Hamamoto H, Sekimizu K, Inoue M. Rational design, synthesis, and biological evaluation of lactam-bridged gramicidin A analogues: discovery of a low-hemolytic antibacterial peptide. Chemmedchem. 10: 540-5. PMID 25510221 DOI: 10.1002/cmdc.201402473  0.6
2015 Murai M, Kaji T, Kuranaga T, Hamamoto H, Sekimizu K, Inoue M. Total synthesis and biological evaluation of the antibiotic lysocin E and its enantiomeric, epimeric, and N-demethylated analogues. Angewandte Chemie (International Ed. in English). 54: 1556-60. PMID 25504563 DOI: 10.1002/anie.201410270  0.6
2015 Hamamoto H, Urai M, Ishii K, Yasukawa J, Paudel A, Murai M, Kaji T, Kuranaga T, Hamase K, Katsu T, Su J, Adachi T, Uchida R, Tomoda H, Yamada M, ... ... Sekimizu K, et al. Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane. Nature Chemical Biology. 11: 127-33. PMID 25485686 DOI: 10.1038/nchembio.1710  0.6
2014 Uchida R, Hanaki H, Matsui H, Hamamoto H, Sekimizu K, Iwatsuki M, Kim YP, Tomoda H. In vitro and in vivo anti-MRSA activities of nosokomycins. Drug Discoveries & Therapeutics. 8: 249-54. PMID 25639304 DOI: 10.5582/ddt.2014.01050  0.6
2014 Matsumoto Y, Sekimizu K. [Drug discovery for treatment against diabetes by using hyperglycemic silkworms]. Seikagaku. the Journal of Japanese Biochemical Society. 86: 613-9. PMID 25509329  0.56
2014 Hamamoto H, Sekimizu K. [Silkworm as a model animal for drug development]. Seikagaku. the Journal of Japanese Biochemical Society. 86: 578-82. PMID 25509323  0.6
2014 Matsumoto Y, Ishii M, Ishii K, Miyaguchi W, Horie R, Inagaki Y, Hamamoto H, Tatematsu K, Uchino K, Tamura T, Sezutsu H, Sekimizu K. Transgenic silkworms expressing human insulin receptors for evaluation of therapeutically active insulin receptor agonists. Biochemical and Biophysical Research Communications. 455: 159-64. PMID 25449269 DOI: 10.1016/j.bbrc.2014.10.143  0.52
2014 Ikuo M, Nagano G, Saito Y, Mao H, Sekimizu K, Kaito C. Inhibition of exotoxin production by mobile genetic element SCCmec-encoded psm-mec RNA is conserved in staphylococcal species. Plos One. 9: e100260. PMID 24926994 DOI: 10.1371/journal.pone.0100260  0.52
2014 Omae Y, Sekimizu K, Kaito C. Identification of Staphylococcus aureus colony-spreading stimulatory factors from mammalian serum. Plos One. 9: e97670. PMID 24831518 DOI: 10.1371/journal.pone.0097670  0.52
2014 Miyashita A, Kizaki H, Kawasaki K, Sekimizu K, Kaito C. Primed immune responses to gram-negative peptidoglycans confer infection resistance in silkworms. The Journal of Biological Chemistry. 289: 14412-21. PMID 24706746 DOI: 10.1074/jbc.M113.525139  0.52
2014 Ishii K, Hamamoto H, Sekimizu K. Establishment of a bacterial infection model using the European honeybee, Apis mellifera L. Plos One. 9: e89917. PMID 24587122 DOI: 10.1371/journal.pone.0089917  0.6
2014 Ishii K, Adachi T, Hara T, Hamamoto H, Sekimizu K. Identification of a Serratia marcescens virulence factor that promotes hemolymph bleeding in the silkworm, Bombyx mori. Journal of Invertebrate Pathology. 117: 61-7. PMID 24530643 DOI: 10.1016/j.jip.2014.02.001  0.6
2014 Imamura K, Imamachi N, Akizuki G, Kumakura M, Kawaguchi A, Nagata K, Kato A, Kawaguchi Y, Sato H, Yoneda M, Kai C, Yada T, Suzuki Y, Yamada T, Ozawa T, ... ... Sekimizu K, et al. Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli. Molecular Cell. 53: 393-406. PMID 24507715 DOI: 10.1016/j.molcel.2014.01.009  0.52
2014 Numata S, Nagata M, Mao H, Sekimizu K, Kaito C. CvfA protein and polynucleotide phosphorylase act in an opposing manner to regulate Staphylococcus aureus virulence. The Journal of Biological Chemistry. 289: 8420-31. PMID 24492613 DOI: 10.1074/jbc.M114.554329  0.52
2014 Ishii K, Adachi T, Yasukawa J, Suzuki Y, Hamamoto H, Sekimizu K. Induction of virulence gene expression in Staphylococcus aureus by pulmonary surfactant. Infection and Immunity. 82: 1500-10. PMID 24452679 DOI: 10.1128/IAI.01635-13  0.6
2014 Adachi T, Ishii K, Matsumoto Y, Hayashi Y, Hamamoto H, Sekimizu K. Niemann-Pick disease type C2 protein induces triglyceride accumulation in silkworm and mammalian cell lines. The Biochemical Journal. 459: 137-47. PMID 24438076 DOI: 10.1042/BJ20130876  0.6
2014 Ishii K, Adachi T, Hamamoto H, Sekimizu K. Serratia marcescens suppresses host cellular immunity via the production of an adhesion-inhibitory factor against immunosurveillance cells. The Journal of Biological Chemistry. 289: 5876-88. PMID 24398686 DOI: 10.1074/jbc.M113.544536  0.6
2013 Ishii K, Hamamoto H, Sekimizu K. [Regulation of innate immunity by the insect cytokine paralytic peptide in the silkworm Bombyx mori]. Seikagaku. the Journal of Japanese Biochemical Society. 85: 1091-5. PMID 24505942  0.6
2013 Hu Y, Hamamoto H, Sekimizu K. Use of silkworms to evaluate the pathogenicity of bacteria attached to cedar pollen. Drug Discoveries & Therapeutics. 7: 153-7. PMID 24071577  0.6
2013 Omae Y, Hanada Y, Sekimizu K, Kaito C. Silkworm apolipophorin protein inhibits hemolysin gene expression of Staphylococcus aureus via binding to cell surface lipoteichoic acids. The Journal of Biological Chemistry. 288: 25542-50. PMID 23873929 DOI: 10.1074/jbc.M113.495051  0.52
2013 Paudel A, Kaneko K, Watanabe A, Matsunaga S, Shigeki M, Kanai M, Motomu K, Hamamoto H, Sekimizu K. Structure-activity relationship study of novel iminothiadiazolo-pyrimidinone antimicrobial agents. The Journal of Antibiotics. 66: 663-7. PMID 23820613 DOI: 10.1038/ja.2013.69  0.6
2013 Dzoyem JP, Hamamoto H, Ngameni B, Ngadjui BT, Sekimizu K. Antimicrobial action mechanism of flavonoids from Dorstenia species. Drug Discoveries & Therapeutics. 7: 66-72. PMID 23715504  0.6
2013 Kaito C, Saito Y, Ikuo M, Omae Y, Mao H, Nagano G, Fujiyuki T, Numata S, Han X, Obata K, Hasegawa S, Yamaguchi H, Inokuchi K, Ito T, Hiramatsu K, ... Sekimizu K, et al. Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence. Plos Pathogens. 9: e1003269. PMID 23592990 DOI: 10.1371/journal.ppat.1003269  0.52
2013 Ishii K, Adachi T, Hamamoto H, Oonishi T, Kamimura M, Imamura K, Sekimizu K. Insect cytokine paralytic peptide activates innate immunity via nitric oxide production in the silkworm Bombyx mori. Developmental and Comparative Immunology. 39: 147-53. PMID 23178406 DOI: 10.1016/j.dci.2012.10.014  0.52
2012 Nakayama M, Kurokawa K, Nakamura K, Lee BL, Sekimizu K, Kubagawa H, Hiramatsu K, Yagita H, Okumura K, Takai T, Underhill DM, Aderem A, Ogasawara K. Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence. Journal of Immunology (Baltimore, Md. : 1950). 189: 5903-11. PMID 23152562 DOI: 10.4049/jimmunol.1201940  0.52
2012 Inagaki Y, Matsumoto Y, Kataoka K, Matsuhashi N, Sekimizu K. Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph. Bmc Pharmacology & Toxicology. 13: 13. PMID 23137391 DOI: 10.1186/2050-6511-13-13  0.56
2012 Ishii K, Adachi T, Imamura K, Takano S, Usui K, Suzuki K, Hamamoto H, Watanabe T, Sekimizu K. Serratia marcescens induces apoptotic cell death in host immune cells via a lipopolysaccharide- and flagella-dependent mechanism. The Journal of Biological Chemistry. 287: 36582-92. PMID 22859304 DOI: 10.1074/jbc.M112.399667  0.52
2012 Miyashita A, Iyoda S, Ishii K, Hamamoto H, Sekimizu K, Kaito C. Lipopolysaccharide O-antigen of enterohemorrhagic Escherichia coli O157:H7 is required for killing both insects and mammals. Fems Microbiology Letters. 333: 59-68. PMID 22612664 DOI: 10.1111/j.1574-6968.2012.02599.x  0.6
2012 Omae Y, Sekimizu K, Kaito C. Inhibition of colony-spreading activity of Staphylococcus aureus by secretion of δ-hemolysin. The Journal of Biological Chemistry. 287: 15570-9. PMID 22411996 DOI: 10.1074/jbc.M112.357848  0.52
2012 Hamamoto H, Urai M, Paudel A, Horie R, Murakami K, Sekimizu K. [Identification of novel therapeutically effective antibiotics using silkworm infection model]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 132: 79-84. PMID 22214583 DOI: JST.JSTAGE/yakushi/132.79  0.6
2012 Paudel A, Hamamoto H, Kobayashi Y, Yokoshima S, Fukuyama T, Sekimizu K. Identification of novel deoxyribofuranosyl indole antimicrobial agents. The Journal of Antibiotics. 65: 53-7. PMID 22167161 DOI: 10.1038/ja.2011.110  0.52
2012 Miyazaki S, Matsumoto Y, Sekimizu K, Kaito C. Evaluation of Staphylococcus aureus virulence factors using a silkworm model. Fems Microbiology Letters. 326: 116-24. PMID 22092964 DOI: 10.1111/j.1574-6968.2011.02439.x  0.56
2012 Kushida A, Horie R, Hattori K, Hamamoto H, Sekimizu K, Tamura H. Xanthurenic acid is an endogenous substrate for the silkworm cytosolic sulfotransferase, bmST1. Journal of Insect Physiology. 58: 83-8. PMID 22036934 DOI: 10.1016/j.jinsphys.2011.10.003  0.6
2011 Hanada Y, Sekimizu K, Kaito C. Silkworm apolipophorin protein inhibits Staphylococcus aureus virulence. The Journal of Biological Chemistry. 286: 39360-9. PMID 21937431 DOI: 10.1074/jbc.M111.278416  0.52
2011 Ueno K, Matsumoto Y, Uno J, Sasamoto K, Sekimizu K, Kinjo Y, Chibana H. Intestinal resident yeast Candida glabrata requires Cyb2p-mediated lactate assimilation to adapt in mouse intestine. Plos One. 6: e24759. PMID 21931845 DOI: 10.1371/journal.pone.0024759  0.56
2011 Fukuyama N, Ino C, Suzuki Y, Kobayashi N, Hamamoto H, Sekimizu K, Orihara Y. Antimicrobial sesquiterpenoids from Laurus nobilis L. Natural Product Research. 25: 1295-303. PMID 21678158 DOI: 10.1080/14786419.2010.502532  0.6
2011 Arimitsu N, Kogure T, Baba T, Nakao K, Hamamoto H, Sekimizu K, Yamamoto A, Nakanishi H, Taguchi R, Tagaya M, Tani K. p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis. Febs Letters. 585: 2171-6. PMID 21640725 DOI: 10.1016/j.febslet.2011.05.050  0.6
2011 Kaito C, Hirano T, Omae Y, Sekimizu K. Digestion of extracellular DNA is required for giant colony formation of Staphylococcus aureus. Microbial Pathogenesis. 51: 142-8. PMID 21539906 DOI: 10.1016/j.micpath.2011.04.007  0.52
2011 Ueda T, Kaito C, Omae Y, Sekimizu K. Sugar-responsive gene expression and the agr system are required for colony spreading in Staphylococcus aureus. Microbial Pathogenesis. 51: 178-85. PMID 21514374 DOI: 10.1016/j.micpath.2011.04.003  0.52
2011 Matsumoto Y, Sumiya E, Sugita T, Sekimizu K. An invertebrate hyperglycemic model for the identification of anti-diabetic drugs. Plos One. 6: e18292. PMID 21479175 DOI: 10.1371/journal.pone.0018292  0.56
2011 Kaito C, Saito Y, Nagano G, Ikuo M, Omae Y, Hanada Y, Han X, Kuwahara-Arai K, Hishinuma T, Baba T, Ito T, Hiramatsu K, Sekimizu K. Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence. Plos Pathogens. 7: e1001267. PMID 21304931 DOI: 10.1371/journal.ppat.1001267  0.52
2010 Wang DL, Qi FH, Xu HL, Inagaki Y, Orihara Y, Sekimizu K, Kokudo N, Wang FS, Tang W. Apoptosis-inducing activity of compounds screened and characterized from cinobufacini by bioassay-guided isolation. Molecular Medicine Reports. 3: 717-22. PMID 21472305 DOI: 10.3892/mmr_00000323  0.48
2010 Ishii K, Hamamoto H, Imamura K, Adachi T, Shoji M, Nakayama K, Sekimizu K. Porphyromonas gingivalis peptidoglycans induce excessive activation of the innate immune system in silkworm larvae. The Journal of Biological Chemistry. 285: 33338-47. PMID 20702417 DOI: 10.1074/jbc.M110.112987  0.52
2010 Tabuchi Y, Shiratsuchi A, Kurokawa K, Gong JH, Sekimizu K, Lee BL, Nakanishi Y. Inhibitory role for D-alanylation of wall teichoic acid in activation of insect Toll pathway by peptidoglycan of Staphylococcus aureus. Journal of Immunology (Baltimore, Md. : 1950). 185: 2424-31. PMID 20639481 DOI: 10.4049/jimmunol.1000625  0.36
2010 Ishii K, Hamamoto H, Kamimura M, Nakamura Y, Noda H, Imamura K, Mita K, Sekimizu K. Insect cytokine paralytic peptide (PP) induces cellular and humoral immune responses in the silkworm Bombyx mori. The Journal of Biological Chemistry. 285: 28635-42. PMID 20622022 DOI: 10.1074/jbc.M110.138446  0.52
2010 Asami Y, Horie R, Hamamoto H, Sekimizu K. Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources. Bmc Pharmacology. 10: 7. PMID 20537191 DOI: 10.1186/1471-2210-10-7  0.6
2010 Matsumoto Y, Xu Q, Miyazaki S, Kaito C, Farr CL, Axelrod HL, Chiu HJ, Klock HE, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Sekimizu K, et al. Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module. Structure (London, England : 1993). 18: 537-47. PMID 20399190 DOI: 10.1016/j.str.2010.02.007  0.52
2010 Ikuo M, Kaito C, Sekimizu K. The cvfC operon of Staphylococcus aureus contributes to virulence via expression of the thyA gene. Microbial Pathogenesis. 49: 1-7. PMID 20347953 DOI: 10.1016/j.micpath.2010.03.010  0.52
2010 Matsuo M, Kurokawa K, Lee BL, Sekimizu K. Shuttle vectors derived from pN315 for study of essential genes in Staphylococcus aureus. Biological & Pharmaceutical Bulletin. 33: 198-203. PMID 20118540 DOI: JST.JSTAGE/bpb/33.198  0.36
2010 Shiratsuchi A, Shimizu K, Watanabe I, Hashimoto Y, Kurokawa K, Razanajatovo IM, Park KH, Park HK, Lee BL, Sekimizu K, Nakanishi Y. Auxiliary role for D-alanylated wall teichoic acid in Toll-like receptor 2-mediated survival of Staphylococcus aureus in macrophages. Immunology. 129: 268-77. PMID 19845797 DOI: 10.1111/j.1365-2567.2009.03168.x  0.36
2009 Hashimoto Y, Tabuchi Y, Sakurai K, Kutsuna M, Kurokawa K, Awasaki T, Sekimizu K, Nakanishi Y, Shiratsuchi A. Identification of lipoteichoic acid as a ligand for draper in the phagocytosis of Staphylococcus aureus by Drosophila hemocytes. Journal of Immunology (Baltimore, Md. : 1950). 183: 7451-60. PMID 19890048 DOI: 10.4049/jimmunol.0901032  0.36
2009 Kurokawa K, Mizumura H, Takaki T, Ishii Y, Ichihashi N, Lee BL, Sekimizu K. Rapid exchange of bound ADP on the Staphylococcus aureus replication initiation protein DnaA. The Journal of Biological Chemistry. 284: 34201-10. PMID 19841480 DOI: 10.1074/jbc.M109.060681  0.36
2009 Kurokawa K, Hamamoto H, Matsuo M, Nishida S, Yamane N, Lee BL, Murakami K, Maki H, Sekimizu K. Evaluation of target specificity of antibacterial agents using Staphylococcus aureus ddlA mutants and D-cycloserine in a silkworm infection model. Antimicrobial Agents and Chemotherapy. 53: 4025-7. PMID 19546371 DOI: 10.1128/AAC.00200-09  0.6
2009 Okuyama-Nishida Y, Akiyama N, Sugimori G, Nomura K, Ogawa K, Homma KJ, Sekimizu K, Tsujimoto M, Natori S. Prevention of death in bacterium-infected mice by a synthetic antimicrobial peptide, L5, through activation of host immunity. Antimicrobial Agents and Chemotherapy. 53: 2510-6. PMID 19289519 DOI: 10.1128/AAC.00863-08  0.52
2009 Nagata M, Ito T, Arimitsu N, Koyama H, Sekimizu K. Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 14: 371-80. PMID 19210546 DOI: 10.1111/j.1365-2443.2008.01277.x  0.36
2009 Kurokawa K, Lee H, Roh KB, Asanuma M, Kim YS, Nakayama H, Shiratsuchi A, Choi Y, Takeuchi O, Kang HJ, Dohmae N, Nakanishi Y, Akira S, Sekimizu K, Lee BL. The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. The Journal of Biological Chemistry. 284: 8406-11. PMID 19139093 DOI: 10.1074/jbc.M809618200  0.36
2009 Takabatake N, Iseki H, Ikehara Y, Kanuka H, Yokoyama N, Sekimizu K, Igarashi I. Isolation and pathogenic characterization of an OB1 variant of Babesia rodhaini which has a glycophorin A-independent pathway to murine red blood cells. Veterinary Parasitology. 159: 97-104. PMID 19084340 DOI: 10.1016/j.vetpar.2008.10.022  0.52
2009 Usui K, Miyazaki S, Kaito C, Sekimizu K. Purification of a soil bacteria exotoxin using silkworm toxicity to measure specific activity Microbial Pathogenesis. 46: 59-62. PMID 19041713 DOI: 10.1016/j.micpath.2008.10.010  0.52
2009 Oku Y, Kurokawa K, Matsuo M, Yamada S, Lee BL, Sekimizu K. Pleiotropic roles of polyglycerolphosphate synthase of lipoteichoic acid in growth of Staphylococcus aureus cells. Journal of Bacteriology. 191: 141-51. PMID 18952789 DOI: 10.1128/JB.01221-08  0.52
2008 Kaito C, Omae Y, Matsumoto Y, Nagata M, Yamaguchi H, Aoto T, Ito T, Hiramatsu K, Sekimizu K. A novel gene, fudoh, in the SCCmec region suppresses the colony spreading ability and virulence of Staphylococcus aureus. Plos One. 3: e3921. PMID 19079549 DOI: 10.1371/journal.pone.0003921  0.56
2007 Takabatake N, Okamura M, Yokoyama N, Ikehara Y, Akimitsu N, Arimitsu N, Hamamoto H, Sekimizu K, Suzuki H, Igarashi I. Glycophorin A-knockout mice, which lost sialoglycoproteins from the red blood cell membrane, are resistant to lethal infection of Babesia rodhaini. Veterinary Parasitology. 148: 93-101. PMID 17651898 DOI: 10.1016/j.vetpar.2007.06.011  0.6
2006 Ito T, Arimitsu N, Takeuchi M, Kawamura N, Nagata M, Saso K, Akimitsu N, Hamamoto H, Natori S, Miyajima A, Sekimizu K. Transcription elongation factor S-II is required for definitive hematopoiesis. Molecular and Cellular Biology. 26: 3194-203. PMID 16581793 DOI: 10.1128/MCB.26.8.3194-3203.2006  0.52
2005 Aramaki Y, Ogawa K, Toh Y, Ito T, Akimitsu N, Hamamoto H, Sekimizu K, Matsusue K, Kono A, Iguchi H, Takiguchi S. Direct interaction between metastasis-associated protein 1 and endophilin 3. Febs Letters. 579: 3731-6. PMID 15978591 DOI: 10.1016/j.febslet.2005.05.069  0.6
2005 Rungruang T, Kaneko O, Murakami Y, Tsuboi T, Hamamoto H, Akimitsu N, Sekimizu K, Kinoshita T, Torii M. Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite. Molecular and Biochemical Parasitology. 140: 13-21. PMID 15694483 DOI: 10.1016/j.molbiopara.2004.11.017  0.6
2004 Hossain MS, Kurokawa K, Akimitsu N, Sekimizu K. DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 905-17. PMID 15461662 DOI: 10.1111/j.1365-2443.2004.00783.x  0.52
2004 Ishida T, Akimitsu N, Kashioka T, Hatano M, Kubota T, Ogata Y, Sekimizu K, Katayama T. DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication. The Journal of Biological Chemistry. 279: 45546-55. PMID 15326179 DOI: 10.1074/jbc.M402762200  0.52
2004 Akimitsu N, Kim HS, Hamamoto H, Kamura K, Fukuma N, Arimitsu N, Ono K, Wataya Y, Torii M, Sekimizu K. Duffy antigen is important for the lethal effect of the lethal strain of Plasmodium yoelii 17XL. Parasitology Research. 93: 499-503. PMID 15278442 DOI: 10.1007/s00436-004-1165-x  0.6
2003 Kashiwazaki M, Tanaka T, Kanda H, Ebisuno Y, Izawa D, Fukuma N, Akimitsu N, Sekimizu K, Monden M, Miyasaka M. A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions. International Immunology. 15: 1219-27. PMID 13679391  0.52
2003 Arimitsu N, Akimitsu N, Kotani N, Takasaki S, Kina T, Hamamoto H, Kamura K, Sekimizu K. Glycophorin A requirement for expression of O-linked antigens on the erythrocyte membrane. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 8: 769-77. PMID 12940824  0.6
2003 Akimitsu N, Kamura K, Toné S, Sakaguchi A, Kikuchi A, Hamamoto H, Sekimizu K. Induction of apoptosis by depletion of DNA topoisomerase IIalpha in mammalian cells. Biochemical and Biophysical Research Communications. 307: 301-7. PMID 12859955  0.6
2003 Hossain MS, Akimitsu N, Kurokawa K, Sekimizu K. Myogenic differentiation of Drosophila Schneider cells by DNA double-strand break-inducing drugs. Differentiation; Research in Biological Diversity. 71: 271-80. PMID 12823228 DOI: 10.1046/j.1432-0436.2003.7104504.x  0.52
2003 Akimitsu N, Adachi N, Hirai H, Hossain MS, Hamamoto H, Kobayashi M, Aratani Y, Koyama H, Sekimizu K. Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIα Genes to Cells. 8: 393-402. PMID 12653966 DOI: 10.1046/j.1365-2443.2003.00643.x  0.52
2003 Fukuma N, Akimitsu N, Hamamoto H, Kusuhara H, Sugiyama Y, Sekimizu K. A role of the Duffy antigen for the maintenance of plasma chemokine concentrations. Biochemical and Biophysical Research Communications. 303: 137-9. PMID 12646177  0.6
2002 Kaito C, Akimitsu N, Watanabe H, Sekimizu K. Silkworm larvae as an animal model of bacterial infection pathogenic to humans. Microbial Pathogenesis. 32: 183-90. PMID 12079408 DOI: 10.1006/mpat.2002.0494  0.52
2002 Koyanagi-Katsuta R, Akimitsu N, Hamamoto H, Arimitsu N, Hatano T, Sekimizu K. Embryonic lethality of mutant mice deficient in the p116 gene. Journal of Biochemistry. 131: 833-7. PMID 12038979  0.6
2002 Kaito C, Kurokawa K, Hossain MS, Akimitsu N, Sekimizu K. Isolation and characterization of temperature-sensitive mutants of the Staphylococcus aureus dnaC gene. Fems Microbiology Letters. 210: 157-64. PMID 12023093 DOI: 10.1111/j.1574-6968.2002.tb11175.x  0.52
2002 Hossain MS, Akimitsu N, Takaki T, Hirai H, Sekimizu K. ICRF-193, a catalytic inhibitor of DNA topoisomerase II, inhibits re-entry into the cell division cycle from quiescent state in mammalian cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 7: 285-94. PMID 11918672  0.52
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