| Year |
Citation |
Score |
| 2018 |
Tunaru S, Bonnavion R, Brandenburger I, Preussner J, Thomas D, Scholich K, Offermanns S. 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1. Nature Communications. 9: 177. PMID 29330456 DOI: 10.1038/S41467-017-02539-4 |
0.372 |
|
| 2017 |
Hohmann SW, Angioni C, Tunaru S, Lee S, Woolf CJ, Offermanns S, Geisslinger G, Scholich K, Sisignano M. The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity. Scientific Reports. 7: 446. PMID 28348394 DOI: 10.1038/S41598-017-00591-0 |
0.315 |
|
| 2017 |
Zinn S, Sisignano M, Kern K, Pierre S, Tunaru S, Jordan H, Suo J, Treutlein EM, Angioni C, Ferreiros N, Leffler A, DeBruin N, Offermanns S, Geisslinger G, Scholich K. The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons. The Journal of Biological Chemistry. PMID 28242764 DOI: 10.1074/Jbc.M116.769125 |
0.408 |
|
| 2016 |
Tunaru S, Chennupati R, Nüsing RM, Offermanns S. Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. Plos One. 11: e0163633. PMID 27662627 DOI: 10.1371/Journal.Pone.0163633 |
0.43 |
|
| 2015 |
Tang C, Ahmed K, Gille A, Lu S, Gröne HJ, Tunaru S, Offermanns S. Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes. Nature Medicine. 21: 173-7. PMID 25581519 DOI: 10.1038/Nm.3779 |
0.313 |
|
| 2013 |
Conzelmann M, Williams EA, Tunaru S, Randel N, Shahidi R, Asadulina A, Berger J, Offermanns S, Jékely G. Conserved MIP receptor-ligand pair regulates Platynereis larval settlement. Proceedings of the National Academy of Sciences of the United States of America. 110: 8224-9. PMID 23569279 DOI: 10.1073/Pnas.1220285110 |
0.337 |
|
| 2012 |
Tunaru S, Althoff TF, Nüsing RM, Diener M, Offermanns S. Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 9179-84. PMID 22615395 DOI: 10.1073/Pnas.1201627109 |
0.369 |
|
| 2011 |
Lukasova M, Hanson J, Tunaru S, Offermanns S. Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials. Trends in Pharmacological Sciences. 32: 700-7. PMID 21944259 DOI: 10.1016/J.Tips.2011.08.002 |
0.397 |
|
| 2010 |
Hanson J, Gille A, Zwykiel S, Lukasova M, Clausen BE, Ahmed K, Tunaru S, Wirth A, Offermanns S. Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice. The Journal of Clinical Investigation. 120: 2910-9. PMID 20664170 DOI: 10.1172/Jci42273 |
0.404 |
|
| 2010 |
Ahmed K, Tunaru S, Tang C, Müller M, Gille A, Sassmann A, Hanson J, Offermanns S. An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81. Cell Metabolism. 11: 311-9. PMID 20374963 DOI: 10.1016/J.Cmet.2010.02.012 |
0.37 |
|
| 2009 |
Ahmed K, Tunaru S, Offermanns S. GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors. Trends in Pharmacological Sciences. 30: 557-62. PMID 19837462 DOI: 10.1016/J.Tips.2009.09.001 |
0.437 |
|
| 2009 |
Ahmed K, Tunaru S, Langhans CD, Hanson J, Michalski CW, Kölker S, Jones PM, Okun JG, Offermanns S. Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis. The Journal of Biological Chemistry. 284: 21928-33. PMID 19561068 DOI: 10.1074/Jbc.M109.019455 |
0.424 |
|
| 2007 |
Kero J, Ahmed K, Wettschureck N, Tunaru S, Wintermantel T, Greiner E, Schütz G, Offermanns S. Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development. The Journal of Clinical Investigation. 117: 2399-407. PMID 17694176 DOI: 10.1172/Jci30380 |
0.307 |
|
| 2005 |
Tunaru S, Lättig J, Kero J, Krause G, Offermanns S. Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G). Molecular Pharmacology. 68: 1271-80. PMID 16099840 DOI: 10.1124/Mol.105.015750 |
0.408 |
|
| 2003 |
Niedernberg A, Tunaru S, Blaukat A, Harris B, Kostenis E. Comparative analysis of functional assays for characterization of agonist ligands at G protein-coupled receptors. Journal of Biomolecular Screening. 8: 500-10. PMID 14567777 DOI: 10.1177/1087057103257555 |
0.392 |
|
| 2003 |
Niedernberg A, Tunaru S, Blaukat A, Ardati A, Kostenis E. Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63. Cellular Signalling. 15: 435-46. PMID 12618218 DOI: 10.1016/S0898-6568(02)00119-5 |
0.405 |
|
| 2003 |
Tunaru S, Kero J, Schaub A, Wufka C, Blaukat A, Pfeffer K, Offermanns S. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nature Medicine. 9: 352-5. PMID 12563315 DOI: 10.1038/Nm824 |
0.439 |
|
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