Year |
Citation |
Score |
2004 |
Connor M, Bagley EE, Mitchell VA, Ingram SL, Christie MJ, Humphrey PP, Vaughan CW. Cellular actions of somatostatin on rat periaqueductal grey neurons in vitro. British Journal of Pharmacology. 142: 1273-80. PMID 15265812 DOI: 10.1038/Sj.Bjp.0705894 |
0.302 |
|
2002 |
Allen JP, Canty AJ, Schulz S, Humphrey PP, Emson PC, Young HM. Identification of cells expressing somatostatin receptor 2 in the gastrointestinal tract of Sstr2 knockout/lacZ knockin mice. The Journal of Comparative Neurology. 454: 329-40. PMID 12442323 DOI: 10.1002/Cne.10466 |
0.528 |
|
Low-probability matches (unlikely to be authored by this person) |
2003 |
Jenkins DW, Sellers LA, Feniuk W, Humphrey PP. Characterization of bradykinin-induced prostaglandin E2 release from cultured rat trigeminal ganglion neurones. European Journal of Pharmacology. 469: 29-36. PMID 12782182 |
0.252 |
|
2006 |
Michel AD, Xing M, Thompson KM, Jones CA, Humphrey PP. Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors. European Journal of Pharmacology. 534: 19-29. PMID 16487507 DOI: 10.1016/j.ejphar.2006.01.009 |
0.251 |
|
2012 |
Long DD, Armstrong SR, Beattie DT, Choi SK, Fatheree PR, Gendron RA, Goldblum AA, Humphrey PP, Marquess DG, Shaw JP, Smith JA, Derek Turner S, Vickery RG. Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: clinical compound TD-2749. Bioorganic & Medicinal Chemistry Letters. 22: 4849-53. PMID 22683222 DOI: 10.1016/j.bmcl.2012.05.034 |
0.171 |
|
2012 |
Long DD, Armstrong SR, Beattie DT, Choi SK, Fatheree PR, Gendron RA, Genov D, Goldblum AA, Humphrey PP, Jiang L, Marquess DG, Shaw JP, Smith JA, Turner SD, Vickery RG. Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT(4) receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation. Bioorganic & Medicinal Chemistry Letters. 22: 6048-52. PMID 22959244 DOI: 10.1016/j.bmcl.2012.08.051 |
0.156 |
|
2009 |
McKinnell RM, Armstrong SR, Beattie DT, Choi SK, Fatheree PR, Gendron RA, Goldblum A, Humphrey PP, Long DD, Marquess DG, Shaw JP, Smith JA, Turner SD, Vickery RG. A multivalent approach to the design and discovery of orally efficacious 5-HT4 receptor agonists. Journal of Medicinal Chemistry. 52: 5330-43. PMID 19663444 DOI: 10.1021/jm900881j |
0.148 |
|
2002 |
Hicks GA, Coldwell JR, Schindler M, Ward PA, Jenkins D, Lynn PA, Humphrey PP, Blackshaw LA. Excitation of rat colonic afferent fibres by 5-HT(3) receptors. The Journal of Physiology. 544: 861-9. PMID 12411529 DOI: 10.1113/jphysiol.2002.025452 |
0.126 |
|
2010 |
Hill CM, Krause KM, Lewis SR, Blais J, Benton BM, Mammen M, Humphrey PP, Kinana A, Janc JW. Specificity of induction of the vanA and vanB operons in vancomycin-resistant enterococci by telavancin. Antimicrobial Agents and Chemotherapy. 54: 2814-8. PMID 20404117 DOI: 10.1128/AAC.01737-09 |
0.119 |
|
2009 |
Lunde CS, Hartouni SR, Janc JW, Mammen M, Humphrey PP, Benton BM. Telavancin disrupts the functional integrity of the bacterial membrane through targeted interaction with the cell wall precursor lipid II. Antimicrobial Agents and Chemotherapy. 53: 3375-83. PMID 19470513 DOI: 10.1128/AAC.01710-08 |
0.089 |
|
2005 |
Higgins DL, Chang R, Debabov DV, Leung J, Wu T, Krause KM, Sandvik E, Hubbard JM, Kaniga K, Schmidt DE, Gao Q, Cass RT, Karr DE, Benton BM, Humphrey PP. Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 49: 1127-34. PMID 15728913 DOI: 10.1128/Aac.49.3.1127-1134.2005 |
0.084 |
|
2008 |
Humphrey PP. The discovery and development of the triptans, a major therapeutic breakthrough. Headache. 48: 685-7. PMID 18471110 DOI: 10.1111/j.1526-4610.2008.01097.x |
0.079 |
|
2013 |
Page C, Humphrey P. Sir David Jack: an extraordinary drug discoverer and developer. British Journal of Clinical Pharmacology. 75: 1213-8. PMID 22994263 DOI: 10.1111/J.1365-2125.2012.04467.X |
0.064 |
|
2003 |
Allen JP, Hathway GJ, Clarke NJ, Jowett MI, Topps S, Kendrick KM, Humphrey PP, Wilkinson LS, Emson PC. Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum. The European Journal of Neuroscience. 17: 1881-95. PMID 12752788 DOI: 10.1046/J.1460-9568.2003.02629.X |
0.058 |
|
2007 |
Humphrey PP. The discovery of a new drug class for the acute treatment of migraine. Headache. 47: S10-9. PMID 17425704 DOI: 10.1111/j.1526-4610.2007.00672.x |
0.025 |
|
Hide low-probability matches. |