Stephen M Moerlein - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Radiopharmaceutical Chemistry

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Criswell SR, Warden MN, Searles Nielsen S, Perlmutter JS, Moerlein SM, Sheppard L, Lenox-Krug J, Checkoway H, Racette BA. Selective D2 receptor PET in manganese-exposed workers. Neurology. PMID 30097475 DOI: 10.1212/Wnl.0000000000006163  0.366
2017 Criswell SR, Nielsen SS, Warden M, Perlmutter JS, Moerlein SM, Flores HP, Huang J, Sheppard L, Seixas N, Checkoway H, Racette BA. [(18)F]FDOPA Positron Emission Tomography in Manganese-Exposed Workers. Neurotoxicology. PMID 28694016 DOI: 10.1016/J.Neuro.2017.07.004  0.305
2016 Eisenstein SA, Bogdan R, Love-Gregory L, Corral-Frías NS, Koller JM, Black KJ, Moerlein SM, Perlmutter JS, Barch DM, Hershey T. Prediction of striatal D2 receptor binding by DRD2/ANKK1 TaqIA allele status. Synapse (New York, N.Y.). PMID 27241797 DOI: 10.1002/Syn.21916  0.318
2015 Yue X, Bognar C, Zhang X, Gaehle GG, Moerlein SM, Perlmutter JS, Tu Z. Automated production of [(18)F]VAT suitable for clinical PET study of vesicular acetylcholine transporter. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 107: 40-46. PMID 26408913 DOI: 10.1016/J.Apradiso.2015.09.010  0.367
2014 Black KJ, Snyder AZ, Mink JW, Tolia VN, Revilla FJ, Moerlein SM, Perlmutter JS. Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia. Plos One. 9: e88121. PMID 24520350 DOI: 10.1371/Journal.Pone.0088121  0.377
2014 Black KJ, Snyder AZ, Mink JW, Tolia VN, Revilla FJ, Moerlein SM, Perlmutter JS. Coronal view of peak [ 18 F]spiperone binding in striatum in cranial and hand dystonia. Plos One. DOI: 10.1371/Journal.Pone.0088121.G002  0.328
2013 Karimi M, Moerlein SM, Videen TO, Su Y, Flores HP, Perlmutter JS. Striatal dopamine D1-like receptor binding is unchanged in primary focal dystonia Movement Disorders. 28: 2002-2006. PMID 24151192 DOI: 10.1002/Mds.25720  0.343
2013 Brown CA, Karimi MK, Tian L, Flores H, Su Y, Tabbal SD, Loftin SK, Moerlein SM, Perlmutter JS. Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaques. Annals of Neurology. 74: 602-10. PMID 23686841 DOI: 10.1002/Ana.23939  0.339
2013 Eisenstein SA, Antenor-Dorsey JA, Gredysa DM, Koller JM, Bihun EC, Ranck SA, Arbeláez AM, Klein S, Perlmutter JS, Moerlein SM, Black KJ, Hershey T. A comparison of D2 receptor specific binding in obese and normal-weight individuals using PET with (N-[(11)C]methyl)benperidol. Synapse (New York, N.Y.). 67: 748-56. PMID 23650017 DOI: 10.1002/Syn.21680  0.336
2013 Karimi M, Tian L, Brown CA, Flores HP, Loftin SK, Videen TO, Moerlein SM, Perlmutter JS. Validation of nigrostriatal positron emission tomography measures: critical limits. Annals of Neurology. 73: 390-6. PMID 23423933 DOI: 10.1002/Ana.23798  0.319
2012 Eisenstein SA, Koller JM, Piccirillo M, Kim A, Antenor-Dorsey JA, Videen TO, Snyder AZ, Karimi M, Moerlein SM, Black KJ, Perlmutter JS, Hershey T. Characterization of extrastriatal D2 in vivo specific binding of [¹⁸F](N-methyl)benperidol using PET. Synapse (New York, N.Y.). 66: 770-80. PMID 22535514 DOI: 10.1002/Syn.21566  0.414
2012 Krohn KA, Moerlein SM, Link JM, Welch MJ. Hot atom chemistry and radiopharmaceuticals Aip Conference Proceedings. 1509: 3-15. DOI: 10.1063/1.4773930  0.501
2011 Criswell SR, Perlmutter JS, Videen TO, Moerlein SM, Flores HP, Birke AM, Racette BA. Reduced uptake of [¹⁸F]FDOPA PET in asymptomatic welders with occupational manganese exposure. Neurology. 76: 1296-301. PMID 21471467 DOI: 10.1212/Wnl.0B013E3182152830  0.32
2011 Karimi M, Moerlein SM, Videen TO, Luedtke RR, Taylor M, Mach RH, Perlmutter JS. Decreased striatal dopamine receptor binding in primary focal dystonia: A D2 or D3 defect? Movement Disorders. 26: 100-106. PMID 20960437 DOI: 10.1002/Mds.23401  0.355
2008 Antenor-Dorsey JAV, Markham J, Moerlein SM, Videen TO, Perlmutter JS. Validation of the reference tissue model for estimation of dopaminergic D2-like receptor binding with [18F](N-methyl)benperidol in humans Nuclear Medicine and Biology. 35: 335-341. PMID 18355689 DOI: 10.1016/J.Nucmedbio.2007.12.004  0.375
2008 Antenor-Dorsey JAV, Laforest R, Moerlein SM, Videen TO, Perlmutter JS. Radiation dosimetry of N-([11C]methyl)benperidol as determined by whole-body PET imaging of primates European Journal of Nuclear Medicine and Molecular Imaging. 35: 771-778. PMID 18071701 DOI: 10.1007/S00259-007-0644-6  0.323
2006 Racette BA, Good L, Antenor JA, McGee-Minnich L, Moerlein SM, Videen TO, Perlmutter JS. [18F]FDOPA PET as an endophenotype for Parkinson's Disease linkage studies. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 245-9. PMID 16528749 DOI: 10.1002/Ajmg.B.30293  0.312
2005 Racette BA, Antenor JA, McGee-Minnich L, Moerlein SM, Videen TO, Kotagal V, Perlmutter JS. [18F]FDOPA PET and clinical features in parkinsonism due to manganism. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 492-6. PMID 15648057 DOI: 10.1002/Mds.20381  0.343
2004 Racette BA, Esper GJ, Antenor J, Black KJ, Burkey A, Moerlein SM, Videen TO, Kotagal V, Ojemann JG, Perlmutter JS. Pathophysiology of parkinsonism due to hydrocephalus. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1617-9. PMID 15489399 DOI: 10.1136/Jnnp.2003.028449  0.303
2004 Mintun MA, Sheline YI, Moerlein SM, Vlassenko AG, Huang Y, Snyder AZ. Decreased hippocampal 5-HT2A receptor binding in major depressive disorder: In vivo measurement with [18F]altanserin positron emission tomography Biological Psychiatry. 55: 217-224. PMID 14744461 DOI: 10.1016/J.Biopsych.2003.08.015  0.308
2004 Moerlein SM, Perlmutter JS, Welch MJ. Radiosynthesis of (N-[11C]methyl)benperidol for PET investigation of D2 receptor binding Radiochimica Acta. 92: 333-339. DOI: 10.1524/Ract.92.4.333.35584  0.508
2002 Moerlein SM, Gaehle GG, Welch MJ. Robotic preparation of Sodium Acetate C 11 Injection for use in clinical PET Nuclear Medicine and Biology. 29: 613-621. PMID 12088733 DOI: 10.1016/S0969-8051(02)00307-4  0.475
2001 Moerlein SM, Welch MJ, Perlmutter JS. Synthesis and evaluation in primates of (N-[11C]methyl)-benperidol as a pet tracer of cerebral D2 receptor binding Journal of Labelled Compounds and Radiopharmaceuticals. 44: S213-S215. DOI: 10.1002/Jlcr.2580440174  0.515
2001 Moerlein SM, Perlmutter JS, Engelbach J, Sharp T, Kim JY, Rowland D, Laforest R, Mody P, Patel G, Lechner K, Welch MJ. Comparison of carbon-11 and fluorine-18 labeled (N-methyl)benperidol (NMB) in rodents using micropet imaging Journal of Labelled Compounds and Radiopharmaceuticals. 44: S455-S456. DOI: 10.1002/Jlcr.25804401160  0.459
1997 Moerlein SM, Perlmutter JS, Markham J, Welch MJ. In vivo kinetics of [18F](N-methyl)benperidol: A novel PET tracer for assessment of dopaminergic D2-like receptor binding Journal of Cerebral Blood Flow and Metabolism. 17: 833-845. PMID 9290581 DOI: 10.1097/00004647-199708000-00002  0.542
1997 Moerlein SM, Perlmutter JS, Cutler PD, Welch MJ. Radiation dosimetry of [18F](N-methyl)benperidol as determined by whole-body PET imaging of primates Nuclear Medicine and Biology. 24: 311-318. PMID 9257329 DOI: 10.1016/S0969-8051(97)00042-5  0.494
1997 Perlmutter JS, Stambuk MK, Markham J, Black KJ, McGee-Minnich L, Jankovic J, Moerlein SM. Decreased [18F]spiperone binding in putamen in idiopathic focal dystonia Journal of Neuroscience. 17: 843-850. PMID 8987805 DOI: 10.1523/Jneurosci.17-02-00843.1997  0.381
1995 Moerlein SM, Perlmutter JS, Welch MJ. Specific, reversible binding of [18F]benperidol to baboon D2 receptors: PET evaluation of an improved 18F-labeled ligand Nuclear Medicine and Biology. 22: 809-815. PMID 8535343 DOI: 10.1016/0969-8051(95)00022-P  0.535
1994 Moerlein SM, Perlmutter JS, Welch MJ, Raichle ME. First-pass extraction fraction of iodine-123 labeled perfusion tracers in living primate brain. Nuclear Medicine and Biology. 21: 847-55. PMID 9234334 DOI: 10.1016/0969-8051(94)90164-3  0.428
1993 Moerlein SM, Weisman RA, Beck D, Li AP, Welch MJ. Metabolism in vitro of radioiodinated N-isopropyl-p-iodoamphetamine by isolated hepatocytes Nuclear Medicine and Biology. 20: 49-56. PMID 8461879 DOI: 10.1016/0969-8051(93)90135-H  0.414
1993 Moerlein SM, Gaehle GG, Lechner KR, Bera RK, Welch MJ. Automated production of oxygen-15 labeled butanol for PET measurement of regional cerebral blood flow Applied Radiation and Isotopes. 44: 1213-1218. PMID 8401450 DOI: 10.1016/0969-8043(93)90067-K  0.471
1992 Moerlein SM, Perlmutter JS. Binding of 5-(2′-[18F]fluoroenthyl)flumazenil to central benzodiazepine receptors measured in living baboon by positron emission tomography European Journal of Pharmacology. 218: 109-115. PMID 1327820 DOI: 10.1016/0014-2999(92)90153-U  0.409
1992 Moerlein SM, Banks WR, Parkinson D. Production of fluorine-18 labeled (3-N-methyl)benperidol for PET investigation of cerebral dopaminergic receptor binding International Journal of Radiation Applications and Instrumentation. Part. 43: 913-917. PMID 1321101 DOI: 10.1016/0883-2889(92)90155-8  0.431
1992 Moerlein SM, Perlmutter JS. Specific binding of 3N-(2′-[18F]fluoroethyl)benperidol to primate cerebral dopaminergic D2 receptors demonstrated in vivo by PET Neuroscience Letters. 148: 97-100. PMID 1300511 DOI: 10.1016/0304-3940(92)90813-M  0.422
1991 Moerlein SM, Perlmutter JS. Central serotonergic S2 binding in Papio anubis measured in vivo with N-ω-[18F]fluoroethylketanserin and PET Neuroscience Letters. 123: 23-26. PMID 2062450 DOI: 10.1016/0304-3940(91)90149-N  0.397
1991 Perlmutter J, Moerlein S, Hwang D, Todd R. Non-steady-state measurement of in vivo radioligand binding with positron emission tomography: specificity analysis and comparison with in vitro binding The Journal of Neuroscience. 11: 1381-1389. DOI: 10.1523/Jneurosci.11-05-01381.1991  0.366
1990 Moerlein SM, Parkinson D, Welch MJ. Radiosynthesis of high effective specific-activity [123I]SCH 23982 for dopamine D-1 receptor-based SPECT imaging International Journal of Radiation Applications and Instrumentation. Part. 41: 381-385. PMID 2158956 DOI: 10.1016/0883-2889(90)90147-9  0.489
1990 Moerlein SM, Lannoye GS, Welch MJ. No-carrier-added radiosynthesis of [123I]HIPDM: N,N,N′-trimethyl-N′-(2-hydroxy-3-methyl-5-[123I]i odobenzyl)-1,3-propanediamine International Journal of Radiation Applications and Instrumentation. Part. 41: 253-257. PMID 2158950 DOI: 10.1016/0883-2889(90)90188-M  0.447
1990 Gropler R, Lee K, Moerlein S, Siegel B, Geltman E. Regional variation in myocardial accumulation of 18 F-fluorodeoxyglucose in fasted normal subjects Journal of the American College of Cardiology. 15: A80. DOI: 10.1016/0735-1097(90)92035-Z  0.303
1989 Moerlein SM, Brodack JW, Siegel BA, Welch MJ. Elimination of contaminant kryptofix 2.2.2 in the routine production of 2-[18F]fluoro-2-deoxy-d-glucose International Journal of Radiation Applications and Instrumentation. Part. 40: 741-743. PMID 2559062 DOI: 10.1016/0883-2889(89)90090-7  0.501
1989 Hwang D, Moerlein S, Dence C, Welch M. Microwave-facilitated synthesis of [18F]-spiperone Journal of Labelled Compounds and Radiopharmaceuticals. 26: 391-392. DOI: 10.1002/Jlcr.25802601167  0.475
1989 Lannoye G, Moerlein S, Welch M. Radiosynthesis of N-(ω-[18F]fluoroalkyl) derivatives of the dopaminergic receptor-binding ligand raclopride Journal of Labelled Compounds and Radiopharmaceuticals. 26: 340-341. DOI: 10.1002/Jlcr.25802601147  0.498
1989 Moerlein S, Welch M. Parameters affecting the labeling of 68Ga-DTPA-LDL: A potential radiopharmaceutical for in-vivo imaging of tissue low-density lipoprotein receptor activity with PET Journal of Labelled Compounds and Radiopharmaceuticals. 26: 285-286. DOI: 10.1002/Jlcr.25802601126  0.454
1989 Welch M, Mathias C, Moerlein S, Connett J, Philpott G. Tyramine-cellobiose (TC) labeling of antibodies: A comparison with other labeling techniques Journal of Labelled Compounds and Radiopharmaceuticals. 26: 269-270. DOI: 10.1002/Jlcr.25802601120  0.381
1987 Hwang DR, Moerlein SM, Lang L, Welch MJ. Application of microwave technology to the synthesis of short-lived radiopharmaceuticals Journal of the Chemical Society, Chemical Communications. 1799-1801. DOI: 10.1039/C39870001799  0.302
1986 Moerlein SM, Stöcklin G, Pawlik G, Wienhard K, Heiss WD. Regional cerebral pharmacokinetics of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as examined by positron emission tomography in a baboon is altered by tranylcypromine Neuroscience Letters. 66: 205-209. PMID 3487753 DOI: 10.1016/0304-3940(86)90191-6  0.33
1986 Moerlein SM, Laufer P, Stöcklin G, Pawlik G, Wienhard K, Heiss WD. Evaluation of 75Br-labelled butyrophenone neuroleptics for imaging cerebral dopaminergic receptor areas using positron emission tomography European Journal of Nuclear Medicine. 12: 211-216. PMID 2876896 DOI: 10.1007/Bf00256924  0.389
1985 Moerlein SM, Laufer P, Stocklin G. Effect of lipophilicity on the in vivo localization of radiolabelled spiperone analogues International Journal of Nuclear Medicine and Biology. 12: 353-356. PMID 3833821 DOI: 10.1016/S0047-0740(85)80003-6  0.352
1985 Moerlein SM, Laufer P, Stöcklin G. Synthesis of no-carrier-added radiobrominated N-alkylated analogues of spiperone Journal of Labelled Compounds and Radiopharmaceuticals. 22: 1007-1022. DOI: 10.1002/Jlcr.2580221004  0.305
1984 Moerlein SM, Welch MJ, Wolf AP. The reactions with benzene of recoiling bromine atoms formed from the 76,77 Kr —â  76'77br transformations. Effects of phase and non-inert chemical additives [1a] Radiochimica Acta. 35: 29-36. DOI: 10.1524/Ract.1984.35.1.29  0.545
1983 Moerlein SM, Welch MJ, Wolf AP. Reactions with aromatic compounds of recoiling bromine atoms formed from the krypton-76,77 .fwdarw. bromine-76,77 transformations. Liquid-phase reactions Journal of the American Chemical Society. 105: 5418-5428. DOI: 10.1021/Ja00354A039  0.546
1983 MOERLEIN SM, WELCH MJ, WOLF AP. ChemInform Abstract: REACTIONS WITH AROMATIC COMPOUNDS OF RECOILING BROMINE ATOMS FORMED FROM THE KRYPTON-76,77 → BROMINE-76,77 TRANSFORMATIONS. LIQUID-PHASE REACTIONS Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198346119  0.554
1981 Moerlein SM, Welch MJ. The chemistry of gallium and indium as related to radiopharmaceutical production International Journal of Nuclear Medicine and Biology. 8: 277-287. PMID 6460006 DOI: 10.1016/0047-0740(81)90034-6  0.333
1981 Frost JJ, Moerlein SM, Welch MJ. Reactions of recoil bromine formed by the 76,77Kr .fwdarw. 76,77Br systems with simple hydrocarbons Journal of the American Chemical Society. 103: 4337-4343. DOI: 10.1021/Ja00405A008  0.407
1981 Frost JJ, Moerlein SM, Welch MJ. Reactions of recoil bromine formed by the 76,77Kr .fwdarw. 76,77Br systems with simple hydrocarbons. Solid-phase reactions Journal of the American Chemical Society. 103: 4332-4337. DOI: 10.1021/Ja00405A007  0.424
1981 Moerlein SM, Welch MJ, Raymond KN, Weitl FL. Tricatecholamide analogs of enterobactin as Ga and in radiopharmaceuticals Journal of Labelled Compounds and Radiopharmaceuticals. 18: 159. DOI: 10.1002/Jlcr.2580180104  0.369
1981 FROST JJ, MOERLEIN SM, WELCH MJ. ChemInform Abstract: REACTIONS OF RECOIL BROMINE FORMED BY THE 76,77KR → 76,77BR SYSTEMS WITH SIMPLE HYDROCARBONS Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198143116  0.419
1981 Frost JJ, Moerlein SM, Welch MJ. Reactions of recoil bromine formed by the 76,77Kr→76,77Br systems with simple hydrocarbons. Solid-phase reactions Journal of the American Chemical Society. 103: 4332-4337. DOI: 10.1002/Chin.198143115  0.422
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