David Weinshenker, Ph.D. - Publications

Affiliations: 
Human Genetics Emory University, Atlanta, GA 
Area:
Norepinephrine

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Year Citation  Score
2024 Liu J, Lustberg DJ, Galvez A, Liles LC, McCann KE, Weinshenker D. Genetic disruption of dopamine β-hydroxylase dysregulates innate responses to predator odor in mice. Neurobiology of Stress. 29: 100612. PMID 38371489 DOI: 10.1016/j.ynstr.2024.100612  0.809
2023 Liu J, Lustberg DJ, Galvez A, Liles LC, McCann KE, Weinshenker D. Genetic disruption of dopamine β-hydroxylase dysregulates innate responses to predator odor in mice. Biorxiv : the Preprint Server For Biology. PMID 38234825 DOI: 10.1101/2023.06.21.545975  0.809
2023 Rowan M, Goettemoeller A, Banks E, McCann K, Kumar P, South K, Olah V, Ramelow C, Duong D, Seyfried N, Rangaraju S, Weinshenker D. Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research Square. PMID 37987015 DOI: 10.21203/rs.3.rs-3370607/v1  0.666
2023 Iannitelli AF, Segal A, Pare JF, Mulvey B, Liles LC, Sloan SA, McCann KE, Dougherty JD, Smith Y, Weinshenker D. Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus. Biorxiv : the Preprint Server For Biology. PMID 36945637 DOI: 10.1101/2023.03.07.530845  0.688
2023 Kelberman MA, Rorabaugh JM, Anderson CR, Marriott A, DePuy SD, Rasmussen K, McCann KE, Weiss JM, Weinshenker D. Age-dependent dysregulation of locus coeruleus firing in a transgenic rat model of Alzheimer's disease. Neurobiology of Aging. 125: 98-108. PMID 36889122 DOI: 10.1016/j.neurobiolaging.2023.01.016  0.67
2023 Harbin NH, Lustberg DJ, Hurst C, Pare JF, Crotty KM, Waters AL, Yeligar SM, Smith Y, Seyfried NT, Weinshenker D, Hepler JR. RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. Biorxiv : the Preprint Server For Biology. PMID 36778349 DOI: 10.1101/2023.02.01.526349  0.717
2023 Iannitelli AF, Kelberman MA, Lustberg DJ, Korukonda A, McCann KE, Mulvey B, Segal A, Liles LC, Sloan SA, Dougherty JD, Weinshenker D. The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease. Eneuro. 10. PMID 36635251 DOI: 10.1523/ENEURO.0483-22.2022  0.784
2022 Kapri D, Vadodaria KC, Rommelfanger KS, Ogbonmwan YE, Liles LC, Fernandes-Thomas KA, Salvi SS, Husain BFA, Weinshenker D, Vaidya VA. Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine beta-hydroxylase deficient mice. Ibro Neuroscience Reports. 13: 420-425. PMID 36386600 DOI: 10.1016/j.ibneur.2022.10.010  0.687
2022 Lustberg DJ, Liu JQ, Iannitelli AF, Vanderhoof SO, Liles LC, McCann KE, Weinshenker D. Norepinephrine and dopamine contribute to distinct repetitive behaviors induced by novel odorant stress in male and female mice. Hormones and Behavior. 144: 105205. PMID 35660247 DOI: 10.1016/j.yhbeh.2022.105205  0.819
2022 Kelberman MA, Anderson CR, Chlan E, Rorabaugh JM, McCann KE, Weinshenker D. Consequences of Hyperphosphorylated Tau in the Locus Coeruleus on Behavior and Cognition in a Rat Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35147547 DOI: 10.3233/JAD-215546  0.663
2021 Acosta MC, Tillage RP, Weinshenker D, Saltzman W. Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus). Hormones and Behavior. 137: 105086. PMID 34808463 DOI: 10.1016/j.yhbeh.2021.105086  0.795
2021 Botz-Zapp CA, Foster SL, Pulley DM, Hempel B, Bi GH, Xi ZX, Newman AH, Weinshenker D, Manvich DF. Effects of the selective dopamine D receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in mice. Behavioural Brain Research. 113506. PMID 34352292 DOI: 10.1016/j.bbr.2021.113506  0.787
2021 Foster SL, Lustberg DJ, Harbin NH, Bramlett SN, Hepler JR, Weinshenker D. RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structures. Psychopharmacology. PMID 34184126 DOI: 10.1007/s00213-021-05892-x  0.794
2021 Tillage RP, Foster SL, Lustberg D, Liles LC, McCann KE, Weinshenker D. Co-released norepinephrine and galanin act on different timescales to promote stress-induced anxiety-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33911187 DOI: 10.1038/s41386-021-01011-8  0.79
2021 Foster SL, Galaj E, Karne SL, Ferré S, Weinshenker D. Cell-type specific expression and behavioral impact of galanin and GalR1 in the locus coeruleus during opioid withdrawal. Addiction Biology. e13037. PMID 33768673 DOI: 10.1111/adb.13037  0.584
2020 Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. 296: 100024. PMID 33410399 DOI: 10.1074/jbc.RA120.016009  0.732
2020 Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. PMID 33154163 DOI: 10.1074/jbc.RA120.016009  0.732
2020 Poe GR, Foote S, Eschenko O, Johansen JP, Bouret S, Aston-Jones G, Harley CW, Manahan-Vaughan D, Weinshenker D, Valentino R, Berridge C, Chandler DJ, Waterhouse B, Sara SJ. Locus coeruleus: a new look at the blue spot. Nature Reviews. Neuroscience. PMID 32943779 DOI: 10.1038/S41583-020-0360-9  0.535
2020 Tillage RP, Wilson GE, Liles LC, Holmes PV, Weinshenker D. Chronic environmental or genetic elevation of galanin in noradrenergic neurons confers stress resilience in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32868458 DOI: 10.1523/Jneurosci.0973-20.2020  0.796
2020 Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, ... ... Weinshenker D, et al. Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32868457 DOI: 10.1523/Jneurosci.1468-19.2020  0.769
2020 Lustberg D, Tillage RP, Bai Y, Pruitt M, Liles LC, Weinshenker D. Noradrenergic circuits in the forebrain control affective responses to novelty. Psychopharmacology. PMID 32821984 DOI: 10.1007/S00213-020-05615-8  0.793
2020 Lustberg D, Tillage RP, Bai Y, Pruitt M, Liles LC, Weinshenker D. Noradrenergic circuits in the forebrain control affective responses to novelty Psychopharmacology. PMID 32821984 DOI: 10.1007/s00213-020-05615-8  0.793
2020 Lustberg D, Iannitelli AF, Tillage RP, Pruitt M, Liles LC, Weinshenker D. Central norepinephrine transmission is required for stress-induced repetitive behavior in two rodent models of obsessive-compulsive disorder. Psychopharmacology. PMID 32313981 DOI: 10.1007/S00213-020-05512-0  0.784
2020 Lustberg D, Weinshenker D. Stressing the potential of guanfacine as a treatment for cocaine use disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32152411 DOI: 10.1038/S41386-020-0649-4  0.739
2020 Tillage RP, Sciolino NR, Plummer NW, Lustberg D, Liles LC, Hsiang M, Powell JM, Smith KG, Jensen P, Weinshenker D. Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors. Brain Structure & Function. PMID 32065256 DOI: 10.1007/S00429-020-02035-4  0.786
2020 Branco RC, Burkett JP, Black CA, Winokur E, Elsworth W, Dhamsania RK, Lohr KM, Schroeder JP, Weinshenker D, Jovanovic T, Miller GW. Vesicular monoamine transporter 2 mediates fear behavior in mice. Genes, Brain, and Behavior. e12634. PMID 31898856 DOI: 10.1111/Gbb.12634  0.426
2020 Chandrasekharan BP, Foster SL, Saeedi B, Weinshenker D, Neish AS. Sa1099 LACTOBACILLUS RHAMNOSUS GG (LGG) -INDUCED ENTERIC NEURONAL DIFFERENTIATION ATTENUATES OPIOID-INDUCED CONSTIPATION Gastroenterology. 158: S-276. DOI: 10.1016/S0016-5085(20)31374-3  0.575
2019 Porter-Stransky KA, Petko AK, Karne SL, Liles LC, Urs NM, Caron MG, Paladini CA, Weinshenker D. Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids. Addiction Biology. e12823. PMID 31441201 DOI: 10.1111/Adb.12823  0.767
2019 Balu DT, Pantazopoulos H, Huang CCY, Muszynski K, Harvey TL, Uno Y, Rorabaugh JM, Galloway CR, Botz-Zapp C, Berretta S, Weinshenker D, Coyle JT. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease. Neurobiology of Disease. 104511. PMID 31212068 DOI: 10.1016/J.Nbd.2019.104511  0.77
2019 Rutkowski TP, Purcell RH, Pollak RM, Grewenow SM, Gafford GM, Malone T, Khan UA, Schroeder JP, Epstein MP, Bassell GJ, Warren ST, Weinshenker D, Caspary T, Mulle JG. Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion. Molecular Psychiatry. PMID 30976085 DOI: 10.1038/S41380-019-0413-5  0.308
2019 Manvich DF, Petko AK, Branco RC, Foster SL, Porter-Stransky KA, Stout KA, Newman AH, Miller GW, Paladini CA, Weinshenker D. Selective D and D receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30879021 DOI: 10.1038/S41386-019-0371-2  0.802
2019 Foster S, Sciolino N, Jensen P, Weinshenker D. F205. Loss of Noradrenergic-Derived Galanin Enhances Opioid Reward and Reinforcement Biological Psychiatry. 85: S293. DOI: 10.1016/J.Biopsych.2019.03.742  0.762
2018 Porter-Stransky KA, Centanni SW, Karne SL, Odil LM, Fekir S, Wong JC, Jerome C, Mitchell HA, Escayg A, Pedersen NP, Winder DG, Mitrano DA, Weinshenker D. Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal. Biological Psychiatry. PMID 30269865 DOI: 10.1016/J.Biopsych.2018.07.027  0.789
2018 Rowson SA, Foster SL, Weinshenker D, Neigh GN. Locomotor sensitization to cocaine in adolescent and adult female Wistar rats. Behavioural Brain Research. PMID 29704596 DOI: 10.1016/J.Bbr.2018.04.035  0.579
2018 Manvich DF, Webster KA, Foster SL, Farrell MS, Ritchie JC, Porter JH, Weinshenker D. The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice. Scientific Reports. 8: 3840. PMID 29497149 DOI: 10.1038/S41598-018-22116-Z  0.797
2017 Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D. Locus coeruleus ablation exacerbates cognitive deficits, neuropathology, and lethality in P301S tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29133432 DOI: 10.1523/Jneurosci.1483-17.2017  0.329
2017 Di Ciano P, Manvich DF, Pushparaj A, Gappasov A, Hess EJ, Weinshenker D, Le Foll B. Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels. Psychopharmacology. PMID 29085979 DOI: 10.1007/S00213-017-4744-0  0.757
2017 Rorabaugh JM, Chalermpalanupap T, Botz-Zapp CA, Fu VM, Lembeck NA, Cohen RM, Weinshenker D. Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease. Brain : a Journal of Neurology. PMID 29053824 DOI: 10.1093/Brain/Awx232  0.335
2017 Christopher MA, Myrick DA, Barwick BG, Engstrom AK, Porter-Stransky KA, Boss JM, Weinshenker D, Levey AI, Katz DJ. LSD1 protects against hippocampal and cortical neurodegeneration. Nature Communications. 8: 805. PMID 28993646 DOI: 10.1038/S41467-017-00922-9  0.749
2017 Giddens MM, Wong JC, Schroeder JP, Farrow EG, Smith BM, Owino S, Soden SE, Meyer RC, Saunders C, LePichon JB, Weinshenker D, Escayg A, Hall RA. GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant. Neurobiology of Disease. PMID 28688853 DOI: 10.1016/J.Nbd.2017.07.006  0.325
2017 Schmidt KT, Schroeder JP, Foster SL, Squires K, Coleman BM, Pitts EG, Epstein MP, Weinshenker D. Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex. Neuropharmacology. PMID 28392265 DOI: 10.1016/J.Neuropharm.2017.04.005  0.616
2017 Porter-Stransky KA, Weinshenker D. Arresting the Development of Addiction: The Role of β-Arrestin2 in Drug Abuse. The Journal of Pharmacology and Experimental Therapeutics. PMID 28302862 DOI: 10.1124/Jpet.117.240622  0.745
2017 Vadodaria KC, Yanpallewar SU, Vadhvani M, Toshniwal D, Liles LC, Rommelfanger KS, Weinshenker D, Vaidya VA. Noradrenergic regulation of plasticity marker expression in the adult rodent piriform cortex. Neuroscience Letters. PMID 28237805 DOI: 10.1016/J.Neulet.2017.02.060  0.695
2017 Porter JH, Manvich DF, Webster KA, Foster SL, Farrell MS, Weinshenker D. Behavioral and Pharmacokinetic Properties of the Putatively-Inert DREADD Ligand Clozapine-N-Oxide (CNO) in Rats and Mice The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.Lb594  0.579
2016 Gyoneva S, Swanger SA, Zhang J, Weinshenker D, Traynelis SF. Altered motility of plaque-associated microglia in a model of Alzheimer's disease. Neuroscience. PMID 27288150 DOI: 10.1016/J.Neuroscience.2016.05.061  0.536
2016 Cubells JF, Schroeder JP, Barrie ES, Manvich DF, Sadee W, Berg T, Mercer K, Stowe TA, Liles LC, Squires KE, Mezher A, Curtin P, Perdomo DL, Szot P, Weinshenker D. Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice. Plos One. 11: e0154864. PMID 27148966 DOI: 10.1371/Journal.Pone.0154864  0.78
2015 Weinshenker D, Holmes PV. Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin. Brain Research. PMID 26607256 DOI: 10.1016/J.Brainres.2015.11.025  0.616
2015 Manvich DF, Stowe TA, Godfrey JR, Weinshenker D. A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats. Biological Psychiatry. PMID 26257242 DOI: 10.1016/J.Biopsych.2015.07.002  0.77
2015 Rose SJ, Yu XY, Heinzer AK, Harrast P, Fan X, Raike RS, Thompson VB, Pare JF, Weinshenker D, Smith Y, Jinnah HA, Hess EJ. A new knock-in mouse model of l-DOPA-responsive dystonia. Brain : a Journal of Neurology. 138: 2987-3002. PMID 26220941 DOI: 10.1093/Brain/Awv212  0.388
2015 Gokhale A, Vrailas-Mortimer A, Larimore J, Comstra HS, Zlatic SA, Werner E, Manvich DF, Iuvone PM, Weinshenker D, Faundez V. Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor. Human Molecular Genetics. 24: 5512-23. PMID 26199316 DOI: 10.1093/Hmg/Ddv282  0.748
2015 Ogbonmwan YE, Schroeder JP, Holmes PV, Weinshenker D. The effects of post-extinction exercise on cocaine-primed and stress-induced reinstatement of cocaine seeking in rats. Psychopharmacology. 232: 1395-403. PMID 25358851 DOI: 10.1007/S00213-014-3778-9  0.59
2015 Sciolino NR, Smith JM, Stranahan AM, Freeman KG, Edwards GL, Weinshenker D, Holmes PV. Galanin mediates features of neural and behavioral stress resilience afforded by exercise. Neuropharmacology. 89: 255-64. PMID 25301278 DOI: 10.1016/J.Neuropharm.2014.09.029  0.789
2015 Liu X, Ye K, Weinshenker D. Norepinephrine Protects against Amyloid-β Toxicity via TrkB. Journal of Alzheimer's Disease : Jad. 44: 251-60. PMID 25208620 DOI: 10.3233/Jad-141062  0.339
2015 Ogbonmwan YE, Sciolino NR, Groves-Chapman JL, Freeman KG, Schroeder JP, Edwards GL, Holmes PV, Weinshenker D. The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex. Addiction Biology. 20: 701-13. PMID 25053279 DOI: 10.1111/Adb.12166  0.794
2014 Barrie ES, Weinshenker D, Verma A, Pendergrass SA, Lange LA, Ritchie MD, Wilson JG, Kuivaniemi H, Tromp G, Carey DJ, Gerhard GS, Brilliant MH, Hebbring SJ, Cubells JF, Pinsonneault JK, et al. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation Research. 115: 1017-25. PMID 25326128 DOI: 10.1161/Circresaha.116.304398  0.332
2014 Gaval-Cruz M, Goertz RB, Puttick DJ, Bowles DE, Meyer RC, Hall RA, Ko D, Paladini CA, Weinshenker D. Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. Addiction Biology. PMID 25123018 DOI: 10.1111/Adb.12174  0.396
2014 Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8845-54. PMID 24966384 DOI: 10.1523/Jneurosci.4027-13.2014  0.347
2014 Cooper DA, Kimmel HL, Manvich DF, Schmidt KT, Weinshenker D, Howell LL. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 350: 144-52. PMID 24817036 DOI: 10.1124/Jpet.113.212357  0.801
2014 Schmidt KT, Weinshenker D. Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors. Molecular Pharmacology. 85: 640-50. PMID 24499709 DOI: 10.1124/Mol.113.090118  0.391
2014 Mitrano DA, Pare JF, Smith Y, Weinshenker D. D1-dopamine and α1-adrenergic receptors co-localize in dendrites of the rat prefrontal cortex. Neuroscience. 258: 90-100. PMID 24231738 DOI: 10.1016/J.Neuroscience.2013.11.002  0.349
2014 Schank JR, King CE, Sun H, Cheng K, Rice KC, Heilig M, Weinshenker D, Schroeder JP. The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1093-101. PMID 24173499 DOI: 10.1038/Npp.2013.309  0.698
2014 Zhang Z, Liu X, Schroeder JP, Chan CB, Song M, Yu SP, Weinshenker D, Ye K. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 638-50. PMID 24022672 DOI: 10.1038/Npp.2013.243  0.309
2013 Manvich DF, DePoy LM, Weinshenker D. Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats. The Journal of Pharmacology and Experimental Therapeutics. 347: 564-73. PMID 24068832 DOI: 10.1124/Jpet.113.207746  0.766
2013 Epps SA, Kahn AB, Holmes PV, Boss-Williams KA, Weiss JM, Weinshenker D. Antidepressant and anticonvulsant effects of exercise in a rat model of epilepsy and depression comorbidity. Epilepsy & Behavior : E&B. 29: 47-52. PMID 23933912 DOI: 10.1016/J.Yebeh.2013.06.023  0.576
2013 Purcell RH, Papale LA, Makinson CD, Sawyer NT, Schroeder JP, Escayg A, Weinshenker D. Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice. Psychopharmacology. 228: 263-70. PMID 23494229 DOI: 10.1007/S00213-013-3034-8  0.377
2013 Schroeder JP, Epps SA, Grice TW, Weinshenker D. The selective dopamine β-hydroxylase inhibitor nepicastat attenuates multiple aspects of cocaine-seeking behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1032-8. PMID 23303068 DOI: 10.1038/Npp.2012.267  0.349
2013 Epps SA, Weinshenker D. Rhythm and blues: animal models of epilepsy and depression comorbidity. Biochemical Pharmacology. 85: 135-46. PMID 22940575 DOI: 10.1016/J.Bcp.2012.08.016  0.321
2013 Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biological Psychiatry. 73: 454-63. PMID 22883210 DOI: 10.1016/J.Biopsych.2012.06.013  0.703
2012 Gaval-Cruz M, Liles LC, Iuvone PM, Weinshenker D. Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice. Plos One. 7: e50583. PMID 23209785 DOI: 10.1371/Journal.Pone.0050583  0.381
2012 Lin SJ, Epps SA, West CH, Boss-Williams KA, Weiss JM, Weinshenker D. Operant psychostimulant self-administration in a rat model of depression. Pharmacology, Biochemistry, and Behavior. 103: 380-5. PMID 23010383 DOI: 10.1016/J.Pbb.2012.09.008  0.328
2012 Epps SA, Tabb KD, Lin SJ, Kahn AB, Javors MA, Boss-Williams KA, Weiss JM, Weinshenker D. Seizure susceptibility and epileptogenesis in a rat model of epilepsy and depression co-morbidity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2756-63. PMID 22871911 DOI: 10.1038/Npp.2012.141  0.777
2012 Mitrano DA, Schroeder JP, Smith Y, Cortright JJ, Bubula N, Vezina P, Weinshenker D. α-1 Adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2161-72. PMID 22588352 DOI: 10.1038/Npp.2012.68  0.395
2012 Rovin ML, Boss-Williams KA, Alisch RS, Ritchie JC, Weinshenker D, West CH, Weiss JM. Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain. Neuropeptides. 46: 81-91. PMID 22317959 DOI: 10.1016/J.Npep.2012.01.001  0.33
2012 Epps⁎ S, Tabb K, Williams K, Weiss J, Weinshenker D. Genetic and behavioural characterization of a rodent model of depression and epilepsy co-morbidity Epilepsy & Behavior. 24: 182-183. DOI: 10.1016/J.Yebeh.2011.04.014  0.759
2011 Keebaugh AC, Mitchell HA, Gaval-Cruz M, Freeman KG, Edwards GL, Weinshenker D, Thomas JW. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. Plos One. 6: e22381. PMID 21818316 DOI: 10.1371/Journal.Pone.0022381  0.708
2010 Lee SE, Simons SB, Heldt SA, Zhao M, Schroeder JP, Vellano CP, Cowan DP, Ramineni S, Yates CK, Feng Y, Smith Y, Sweatt JD, Weinshenker D, Ressler KJ, Dudek SM, et al. RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory. Proceedings of the National Academy of Sciences of the United States of America. 107: 16994-8. PMID 20837545 DOI: 10.1073/Pnas.1005362107  0.597
2010 Weinshenker D. Cocaine sobers up. Nature Medicine. 16: 969-70. PMID 20823878 DOI: 10.1038/Nm0910-969  0.342
2010 Schroeder JP, Cooper DA, Schank JR, Lyle MA, Gaval-Cruz M, Ogbonmwan YE, Pozdeyev N, Freeman KG, Iuvone PM, Edwards GL, Holmes PV, Weinshenker D. Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2440-9. PMID 20736996 DOI: 10.1038/Npp.2010.127  0.768
2010 Skinbjerg M, Seneca N, Liow JS, Hong J, Weinshenker D, Pike VW, Halldin C, Sibley DR, Innis RB. Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding. Synapse (New York, N.Y.). 64: 699-703. PMID 20336622 DOI: 10.1002/Syn.20781  0.339
2010 Yanpallewar SU, Fernandes K, Marathe SV, Vadodaria KC, Jhaveri D, Rommelfanger K, Ladiwala U, Jha S, Muthig V, Hein L, Bartlett P, Weinshenker D, Vaidya VA. Alpha2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1096-109. PMID 20089918 DOI: 10.1523/Jneurosci.2309-09.2010  0.691
2010 Mitchell HA, Weinshenker D. Good night and good luck: norepinephrine in sleep pharmacology. Biochemical Pharmacology. 79: 801-9. PMID 19833104 DOI: 10.1016/J.Bcp.2009.10.004  0.667
2009 Gaval-Cruz M, Weinshenker D. mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse. Molecular Interventions. 9: 175-87. PMID 19720750 DOI: 10.1124/Mi.9.4.6  0.304
2009 Taylor TN, Caudle WM, Shepherd KR, Noorian A, Jackson CR, Iuvone PM, Weinshenker D, Greene JG, Miller GW. Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8103-13. PMID 19553450 DOI: 10.1523/Jneurosci.1495-09.2009  0.364
2009 Jang SW, Liu X, Chan CB, Weinshenker D, Hall RA, Xiao G, Ye K. Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chemistry & Biology. 16: 644-56. PMID 19549602 DOI: 10.1016/J.Chembiol.2009.05.010  0.322
2009 Gilsbach R, Röser C, Beetz N, Brede M, Hadamek K, Haubold M, Leemhuis J, Philipp M, Schneider J, Urbanski M, Szabo B, Weinshenker D, Hein L. Genetic dissection of alpha2-adrenoceptor functions in adrenergic versus nonadrenergic cells. Molecular Pharmacology. 75: 1160-70. PMID 19251826 DOI: 10.1124/Mol.109.054544  0.309
2009 Xiao Z, Deng PY, Rojanathammanee L, Yang C, Grisanti L, Permpoonputtana K, Weinshenker D, Doze VA, Porter JE, Lei S. Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels. The Journal of Biological Chemistry. 284: 10980-91. PMID 19244246 DOI: 10.1074/Jbc.M806760200  0.324
2009 Rommelfanger KS, Mitrano DA, Smith Y, Weinshenker D. Light and electron microscopic localization of alpha-1 adrenergic receptor immunoreactivity in the rat striatum and ventral midbrain. Neuroscience. 158: 1530-40. PMID 19068224 DOI: 10.1016/J.Neuroscience.2008.11.019  0.686
2009 Mitchell HA, Bogenpohl JW, Liles LC, Epstein MP, Bozyczko-Coyne D, Williams M, Weinshenker D. Corrigendum to "Behavioral responses of dopamine β-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action" (DOI:10.1016/j.pbb.2008.07.014) Pharmacology Biochemistry and Behavior. 92: 197. DOI: 10.1016/j.pbb.2008.12.001  0.707
2008 Swoap SJ, Weinshenker D. Norepinephrine controls both torpor initiation and emergence via distinct mechanisms in the mouse. Plos One. 3: e4038. PMID 19107190 DOI: 10.1371/Journal.Pone.0004038  0.375
2008 Weinshenker D, Warren ST. Neuroscience: fragile dopamine. Nature. 455: 607-8. PMID 18833269 DOI: 10.1038/455607A  0.314
2008 Mitchell HA, Bogenpohl JW, Liles LC, Epstein MP, Bozyczko-Coyne D, Williams M, Weinshenker D. Behavioral responses of dopamine beta-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action. Pharmacology, Biochemistry, and Behavior. 91: 217-22. PMID 18703079 DOI: 10.1016/J.Pbb.2008.07.014  0.74
2008 Lin Y, Quartermain D, Dunn AJ, Weinshenker D, Stone EA. Possible dopaminergic stimulation of locus coeruleus alpha1-adrenoceptors involved in behavioral activation. Synapse (New York, N.Y.). 62: 516-23. PMID 18435418 DOI: 10.1002/Syn.20517  0.369
2008 Gaval-Cruz M, Schroeder JP, Liles LC, Javors MA, Weinshenker D. Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures. Pharmacology, Biochemistry, and Behavior. 89: 556-62. PMID 18329701 DOI: 10.1016/J.Pbb.2008.02.009  0.378
2008 Schank JR, Liles LC, Weinshenker D. Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety. Biological Psychiatry. 63: 1007-12. PMID 18083142 DOI: 10.1016/J.Biopsych.2007.10.018  0.731
2008 Weinshenker D, Ferrucci M, Busceti CL, Biagioni F, Lazzeri G, Liles LC, Lenzi P, Pasquali L, Murri L, Paparelli A, Fornai F. Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine. Journal of Neurochemistry. 105: 471-83. PMID 18042179 DOI: 10.1111/J.1471-4159.2007.05145.X  0.414
2007 Rommelfanger KS, Edwards GL, Freeman KG, Liles LC, Miller GW, Weinshenker D. Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 13804-9. PMID 17702867 DOI: 10.1073/Pnas.0702753104  0.709
2007 Rommelfanger KS, Weinshenker D. Norepinephrine: The redheaded stepchild of Parkinson's disease. Biochemical Pharmacology. 74: 177-90. PMID 17416354 DOI: 10.1016/J.Bcp.2007.01.036  0.68
2007 Tabb K, Boss-Williams KA, Weiss JM, Weinshenker D. Rats bred for susceptibility to depression-like phenotypes have higher kainic acid-induced seizure mortality than their depression-resistant counterparts. Epilepsy Research. 74: 140-6. PMID 17400428 DOI: 10.1016/J.Eplepsyres.2007.02.006  0.772
2007 Weinshenker D, Schroeder JP. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1433-51. PMID 17164822 DOI: 10.1038/Sj.Npp.1301263  0.383
2007 Paladini CA, Beckstead MJ, Weinshenker D. Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse. Neuroscience. 144: 1067-74. PMID 17156935 DOI: 10.1016/J.Neuroscience.2006.10.032  0.395
2007 Sowden GL, Drucker DJ, Weinshenker D, Swoap SJ. Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R962-70. PMID 17038440 DOI: 10.1152/Ajpregu.00405.2006  0.345
2006 Mitchell HA, Ahern TH, Liles LC, Javors MA, Weinshenker D. The effects of norepinephrine transporter inactivation on locomotor activity in mice. Biological Psychiatry. 60: 1046-52. PMID 16893531 DOI: 10.1016/J.Biopsych.2006.03.057  0.7
2006 Sanders JD, Szot P, Weinshenker D, Happe HK, Bylund DB, Murrin LC. Analysis of brain adrenergic receptors in dopamine-beta-hydroxylase knockout mice. Brain Research. 1109: 45-53. PMID 16854392 DOI: 10.1016/J.Brainres.2006.06.033  0.301
2006 Reiner DJ, Weinshenker D, Tian H, Thomas JH, Nishiwaki K, Miwa J, Gruninger T, Leboeuf B, Garcia LR. Behavioral genetics of caenorhabditis elegans unc-103-encoded erg-like K(+) channel. Journal of Neurogenetics. 20: 41-66. PMID 16807195 DOI: 10.1080/01677060600788826  0.462
2006 Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T. Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.). 60: 319-46. PMID 16786561 DOI: 10.1002/Syn.20303  0.375
2006 Olson VG, Heusner CL, Bland RJ, During MJ, Weinshenker D, Palmiter RD. Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward. Science (New York, N.Y.). 311: 1017-20. PMID 16484499 DOI: 10.1126/Science.1119311  0.802
2006 Swoap SJ, Gutilla MJ, Liles LC, Smith RO, Weinshenker D. The full expression of fasting-induced torpor requires beta 3-adrenergic receptor signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 241-5. PMID 16399693 DOI: 10.1523/Jneurosci.3721-05.2006  0.332
2006 Schank JR, Ventura R, Puglisi-Allegra S, Alcaro A, Cole CD, Liles LC, Seeman P, Weinshenker D. Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2221-30. PMID 16395294 DOI: 10.1038/Sj.Npp.1301000  0.747
2006 Martillotti J, Weinshenker D, Liles LC, Eagles DA. A ketogenic diet and knockout of the norepinephrine transporter both reduce seizure severity in mice. Epilepsy Research. 68: 207-11. PMID 16356685 DOI: 10.1016/J.Eplepsyres.2005.11.002  0.338
2006 Ahern TH, Javors MA, Eagles DA, Martillotti J, Mitchell HA, Liles LC, Weinshenker D. The effects of chronic norepinephrine transporter inactivation on seizure susceptibility in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 730-8. PMID 16052243 DOI: 10.1038/Sj.Npp.1300847  0.692
2005 Bourdélat-Parks BN, Anderson GM, Donaldson ZR, Weiss JM, Bonsall RW, Emery MS, Liles LC, Weinshenker D. Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice. Psychopharmacology. 183: 72-80. PMID 16163519 DOI: 10.1007/S00213-005-0139-8  0.343
2005 Schank JR, Liles LC, Weinshenker D. Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice. Epilepsy Research. 65: 23-31. PMID 15955669 DOI: 10.1016/J.Eplepsyres.2005.03.010  0.713
2005 Marino MD, Bourdélat-Parks BN, Cameron Liles L, Weinshenker D. Genetic reduction of noradrenergic function alters social memory and reduces aggression in mice. Behavioural Brain Research. 161: 197-203. PMID 15922045 DOI: 10.1016/J.Bbr.2005.02.005  0.349
2005 Gottsch ML, Zeng H, Hohmann JG, Weinshenker D, Clifton DK, Steiner RA. Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2). Molecular and Cellular Biology. 25: 4804-11. PMID 15899880 DOI: 10.1128/Mcb.25.11.4804-4811.2005  0.355
2005 Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, Grandy DK, Premont RT, Sotnikova TD, Boksa P, El-Ghundi M, O'dowd BF, George SR, Perreault ML, Männistö PT, Robinson S, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3513-8. PMID 15716360 DOI: 10.1073/Pnas.0409766102  0.628
2004 Rommelfanger KS, Weinshenker D, Miller GW. Reduced MPTP toxicity in noradrenaline transporter knockout mice. Journal of Neurochemistry. 91: 1116-24. PMID 15569255 DOI: 10.1111/J.1471-4159.2004.02785.X  0.727
2004 Tabb K, Szot P, White SS, Liles LC, Weinshenker D. The ketogenic diet does not alter brain expression of orexigenic neuropeptides. Epilepsy Research. 62: 35-9. PMID 15519130 DOI: 10.1016/J.Eplepsyres.2004.08.002  0.763
2004 Szot P, Lester M, Laughlin ML, Palmiter RD, Liles LC, Weinshenker D. The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors. Neuroscience. 126: 795-803. PMID 15183527 DOI: 10.1016/J.Neuroscience.2004.04.030  0.514
2004 Hohmann JG, Teklemichael DN, Weinshenker D, Wynick D, Clifton DK, Steiner RA. Obesity and endocrine dysfunction in mice with deletions of both neuropeptide Y and galanin. Molecular and Cellular Biology. 24: 2978-85. PMID 15024085 DOI: 10.1128/Mcb.24.7.2978-2985.2004  0.318
2004 Swoap SJ, Weinshenker D, Palmiter RD, Garber G. Dbh(-/-) mice are hypotensive, have altered circadian rhythms, and have abnormal responses to dieting and stress. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R108-13. PMID 12969876 DOI: 10.1152/Ajpregu.00405.2003  0.504
2002 Weinshenker D, Miller NS, Blizinsky K, Laughlin ML, Palmiter RD. Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals. Proceedings of the National Academy of Sciences of the United States of America. 99: 13873-7. PMID 12370425 DOI: 10.1073/Pnas.212519999  0.587
2002 Weinshenker D, White SS, Javors MA, Palmiter RD, Szot P. Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo. Brain Research. 946: 239-46. PMID 12137927 DOI: 10.1016/S0006-8993(02)02889-5  0.547
2002 Weinshenker D, Szot P. The role of catecholamines in seizure susceptibility: new results using genetically engineered mice. Pharmacology & Therapeutics. 94: 213-33. PMID 12113799 DOI: 10.1016/S0163-7258(02)00218-8  0.362
2002 Jasmin L, Tien D, Weinshenker D, Palmiter RD, Green PG, Janni G, Ohara PT. The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proceedings of the National Academy of Sciences of the United States of America. 99: 1029-34. PMID 11805341 DOI: 10.1073/Pnas.012598599  0.512
2001 Weinshenker D, Szot P, Miller NS, Rust NC, Hohmann JG, Pyati U, White SS, Palmiter RD. Genetic comparison of seizure control by norepinephrine and neuropeptide Y. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7764-9. PMID 11567066 DOI: 10.1523/Jneurosci.21-19-07764.2001  0.533
2001 Szot P, Weinshenker D, Rho JM, Storey TW, Schwartzkroin PA. Norepinephrine is required for the anticonvulsant effect of the ketogenic diet. Brain Research. Developmental Brain Research. 129: 211-4. PMID 11506865 DOI: 10.1016/S0165-3806(01)00213-9  0.348
2001 Weinshenker D, Szot P, Miller NS, Palmiter RD. Alpha(1) and beta(2) adrenoreceptor agonists inhibit pentylenetetrazole-induced seizures in mice lacking norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 298: 1042-8. PMID 11504801  0.441
2000 Weinshenker D, Rust NC, Miller NS, Palmiter RD. Ethanol-associated behaviors of mice lacking norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3157-64. PMID 10777779 DOI: 10.1523/Jneurosci.20-09-03157.2000  0.484
1999 Szot P, Weinshenker D, White SS, Robbins CA, Rust NC, Schwartzkroin PA, Palmiter RD. Norepinephrine-deficient mice have increased susceptibility to seizure-inducing stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10985-92. PMID 10594079 DOI: 10.1523/Jneurosci.19-24-10985.1999  0.52
1999 Weinshenker D, Wei A, Salkoff L, Thomas JH. Block of an ether-a-go-go-like K(+) channel by imipramine rescues egl-2 excitation defects in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9831-40. PMID 10559392 DOI: 10.1523/Jneurosci.19-22-09831.1999  0.426
1995 Reiner DJ, Weinshenker D, Thomas JH. Analysis of dominant mutations affecting muscle excitation in Caenorhabditis elegans. Genetics. 141: 961-76. PMID 8582640  0.332
1995 Weinshenker D, Garriga G, Thomas JH. Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6975-85. PMID 7472454 DOI: 10.1523/Jneurosci.15-10-06975.1995  0.454
Low-probability matches (unlikely to be authored by this person)
2017 Chalermpalanupap T, Weinshenker D, Rorabaugh JM. Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus. Neural Plasticity. 2017: 7829507. PMID 29038736 DOI: 10.1155/2017/7829507  0.299
2010 Moreira CG, Weinshenker D, Sperandio V. QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo. Infection and Immunity. 78: 914-26. PMID 20028809 DOI: 10.1128/Iai.01038-09  0.298
2019 Kang SS, Liu X, Ahn EH, Xiang J, Manfredsson FP, Yang X, Luo HR, Liles LC, Weinshenker D, Ye K. Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus. The Journal of Clinical Investigation. PMID 31793911 DOI: 10.1172/Jci130513  0.296
2018 Weinshenker D. Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease. Trends in Neurosciences. PMID 29475564 DOI: 10.1016/J.Tins.2018.01.010  0.295
2009 Goldenstein BL, Nelson BW, Xu K, Luger EJ, Pribula JA, Wald JM, O'Shea LA, Weinshenker D, Charbeneau RA, Huang X, Neubig RR, Doze VA. Regulator of G protein signaling protein suppression of Galphao protein-mediated alpha2A adrenergic receptor inhibition of mouse hippocampal CA3 epileptiform activity. Molecular Pharmacology. 75: 1222-30. PMID 19225179 DOI: 10.1124/Mol.108.054296  0.294
2004 Depondt C, Cock HR, Healy DG, Burley MW, Weinshenker D, Wood NW, Goldstein DB, Sisodiya SM. The -1021C->T DBH gene variant is not associated with epilepsy or antiepileptic drug response. Neurology. 63: 1497-9. PMID 15505174 DOI: 10.1212/01.Wnl.0000142092.16719.Ad  0.292
2012 Osuala K, Baker CN, Nguyen HL, Martinez C, Weinshenker D, Ebert SN. Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism. Physiological Genomics. 44: 934-47. PMID 22911456 DOI: 10.1152/Physiolgenomics.00180.2011  0.289
2008 Weinshenker D. Functional consequences of locus coeruleus degeneration in Alzheimer's disease. Current Alzheimer Research. 5: 342-5. PMID 18537547 DOI: 10.2174/156720508784533286  0.284
2013 Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimer's Research & Therapy. 5: 21. PMID 23634965 DOI: 10.1186/Alzrt175  0.283
2016 Rutkowski TP, Schroeder JP, Gafford GM, Warren ST, Weinshenker D, Caspary T, Mulle JG. Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders. Journal of Neuroscience Research. PMID 27859486 DOI: 10.1002/Jnr.23970  0.277
2013 Swoap SJ, Weinshenker D. Leptin deficiency restores torpor in Dbh −/− mice. Plos One. DOI: 10.1371/Journal.Pone.0004038.G002  0.271
2019 Rowson SA, Bekhbat M, Kelly SD, Binder EB, Hyer MM, Shaw G, Bent MA, Hodes G, Tharp G, Weinshenker D, Qin Z, Neigh GN. Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30710108 DOI: 10.1038/S41386-019-0321-Z  0.27
2019 Rasmussen SA, Daenzer JMI, MacWilliams JA, Head ST, Williams M, Geurts AM, Schroeder J, Weinshenker D, Fridovich-Keil JL. A GALT-null rat model of classic galactosemia mimics relevant patient outcomes and reveals tissue-specific and longitudinal differences in galactose metabolism. Journal of Inherited Metabolic Disease. PMID 31845342 DOI: 10.1002/Jimd.12205  0.265
2016 Moreira CG, Russell R, Mishra AA, Narayanan S, Ritchie JM, Waldor MK, Curtis MM, Winter SE, Weinshenker D, Sperandio V. Bacterial Adrenergic Sensors Regulate Virulence of Enteric Pathogens in the Gut. Mbio. 7. PMID 27273829 DOI: 10.1128/Mbio.00826-16  0.259
2012 Baker C, Taylor DG, Osuala K, Natarajan A, Molnar PJ, Hickman J, Alam S, Moscato B, Weinshenker D, Ebert SN. Adrenergic deficiency leads to impaired electrical conduction and increased arrhythmic potential in the embryonic mouse heart. Biochemical and Biophysical Research Communications. 423: 536-41. PMID 22683331 DOI: 10.1016/J.Bbrc.2012.05.163  0.254
2008 Weinshenker D. The contribution of norepinephrine and orexigenic neuropeptides to the anticonvulsant effect of the ketogenic diet. Epilepsia. 49: 104-7. PMID 19049603 DOI: 10.1111/J.1528-1167.2008.01850.X  0.252
2005 Weinshenker D, Wilson MM, Williams KM, Weiss JM, Lamb NE, Twigger SN. A new method for identifying informative genetic markers in selectively bred rats. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 784-91. PMID 16261420 DOI: 10.1007/S00335-005-0047-6  0.232
2008 Luger E, Davis K, Goldenstein B, Nelson B, Xu K, Pribula J, Wald J, Weinshenker D, Doze V. Alpha2A adrenergic receptor‐mediated inhibition of mouse hippocampal CA3 network activity The Faseb Journal. 22: 98-98. DOI: 10.1096/Fasebj.22.2_Supplement.98  0.224
2008 Weinshenker D. Special addiction issue editorial Biochemical Pharmacology. 75: 1. DOI: 10.1016/J.Bcp.2007.09.028  0.223
2006 Chalermpalanupap T, Rorabaugh JM, DePuy SD, Rasmussen K, Lah JJ, Levey AI, Cohen RM, Weinshenker D. F4-07-04: THE CONSEQUENCES OF TAU IN THE LOCUS COERULEUS ON ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1394-P1394. DOI: 10.1016/J.Jalz.2018.06.2891  0.221
2016 Chalermpalanupap T, Bradner J, Chen T, Jerome C, Schroeder J, Lah JJ, Tansey MG, Levey AI, Weinshenker D. P3-069: Elucidating the Relationship Between Hyperphosphorylated TAU and Locus Coeruleus Degeneration in Alzheimer’s Disease Alzheimer's & Dementia. 12: P844-P844. DOI: 10.1016/J.Jalz.2016.06.1727  0.22
2019 Levey AI, Lah JJ, Hu WT, Wingo TS, Hales CM, Manzanares C, Tansey MG, Goldstein DS, Zhao L, Galasko DR, Edland SD, Hanfelt J, Weinshenker D. O4-11-05: A PROOF OF CONCEPT PHASE II STUDY REPURPOSING ATOMOXETINE FOR NEUROPROTECTION IN MILD COGNITIVE IMPAIRMENT: EVIDENCE FOR TARGET ENGAGEMENT, REGULATION OF CSF BIOMARKERS, AND DISEASE-MODIFYING POTENTIAL Alzheimer's & Dementia. 15: P1263-P1264. DOI: 10.1016/J.Jalz.2019.06.4804  0.214
2010 Moreira CG, Weinshenker D, Sperandio V. QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo (Infection and Immunity (2010) 78, 3, (914-926)) Infection and Immunity. 78: 3647. DOI: 10.1128/Iai.00602-10  0.202
2018 Rutkowski T, Schroeder J, Gafford G, Grewenow S, Malone T, Warren S, Mulle J, Weinshenker D, Caspary T. T224. A Mouse Model of the 3q29 Deletion Biological Psychiatry. 83: S215. DOI: 10.1016/J.Biopsych.2018.02.561  0.197
2023 Iannitelli AF, Weinshenker D. Riddles in the dark: Decoding the relationship between neuromelanin and neurodegeneration in locus coeruleus neurons. Neuroscience and Biobehavioral Reviews. 152: 105287. PMID 37327835 DOI: 10.1016/j.neubiorev.2023.105287  0.194
2019 Pollak R, Purcell R, Rutkowski T, Malone T, Pachura K, Bassell GJ, Epstein MP, Caspary T, Dawson PA, Jones DP, Warren ST, Weinshenker D, Zwick ME, Mulle JG. T11Metabolic Dysfunction As A Contributor To Phenotypes Of The Schizophrenia-Associated 3Q29 Deletion European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.210  0.19
2020 Galloway C, McCann R, Kelberman M, Chawla S, Weinshenker D. The behavioral effects of virally induced human tau expression in the locus coeruleus of TgF344‐AD rats Alzheimer's & Dementia. 16. DOI: 10.1002/alz.038175  0.183
2014 Heldt SA, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler KJ. BDNF deletion or TrkB impairment in amygdala inhibits both appetitive and aversive learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2444-50. PMID 24523535 DOI: 10.1523/Jneurosci.4085-12.2014  0.183
2013 Gaval-Cruz M, Goertz B, Puttick DJ, Meyer RC, Bowles DE, Hall RA, Paladini CA, Weinshenker D. Chronic loss of Noradrenergic Tone Produces β-Arrestin2-Mediated Cocaine Hypersensitivity and a GαI to Gαs switch in D2 Receptor Coupling in the Nucleus Accumbens Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 111. DOI: 10.1016/B978-0-12-800044-1.00097-0  0.18
2015 Shepard KN, Liles LC, Weinshenker D, Liu RC. Norepinephrine is necessary for experience-dependent plasticity in the developing mouse auditory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2432-7. PMID 25673838 DOI: 10.1523/JNEUROSCI.0532-14.2015  0.176
2024 Rowson S, Bekhbat M, Kelly S, Hyer MM, Dyer S, Weinshenker D, Neigh G. Chronic adolescent stress alters GR-FKBP5 interactions in the hippocampus of adult female rats. Stress (Amsterdam, Netherlands). 27: 2312467. PMID 38557197 DOI: 10.1080/10253890.2024.2312467  0.163
2023 Theron V, Harvey BH, Botha T, Weinshenker D, Wolmarans W. Life-threatening, high-intensity trauma- and context-dependent anxiety in zebrafish and its modulation by epinephrine. Hormones and Behavior. 153: 105376. PMID 37244195 DOI: 10.1016/j.yhbeh.2023.105376  0.157
2024 McCall A, Forouhandehpour R, Celebi S, Richard-Malenfant C, Hamati R, Guimond S, Tuominen L, Weinshenker D, Jaworska N, McQuaid RJ, Shlik J, Robillard R, Kaminsky Z, Cassidy CM. Evidence for locus coeruleus-norepinephrine system abnormality in military PTSD revealed by neuromelanin-sensitive MRI. Biological Psychiatry. PMID 38296219 DOI: 10.1016/j.biopsych.2024.01.013  0.148
2022 Kang SS, Meng L, Zhang X, Wu Z, Mancieri A, Xie B, Liu X, Weinshenker D, Peng J, Zhang Z, Ye K. Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation. Nature Structural & Molecular Biology. PMID 35332321 DOI: 10.1038/s41594-022-00745-3  0.146
2022 Pollak RM, Purcell RH, Rutkowski TP, Malone T, Pachura KJ, Bassell GJ, Epstein MP, Dawson PA, Smith MR, Jones DP, Zwick ME, Warren ST, Caspary T, Weinshenker D, Mulle JG. Metabolic effects of the schizophrenia-associated 3q29 deletion. Translational Psychiatry. 12: 66. PMID 35177588 DOI: 10.1038/s41398-022-01824-1  0.144
2023 Levinstein MR, De Oliveira PA, Casajuana-Martin N, Quiroz C, Budinich RC, Rais R, Rea W, Ventriglia EN, Llopart N, Casadó-Anguera V, Moreno E, Walther D, Glatfelter GC, Weinshenker D, Zarate CA, et al. Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone. Molecular Psychiatry. PMID 38145984 DOI: 10.1038/s41380-023-02353-z  0.142
2020 Kelberman M, Keilholz S, Weinshenker D. What's That (Blue) Spot on my MRI? Multimodal Neuroimaging of the Locus Coeruleus in Neurodegenerative Disease. Frontiers in Neuroscience. 14: 583421. PMID 33122996 DOI: 10.3389/fnins.2020.583421  0.136
2021 Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, ... ... Weinshenker D, et al. A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a Journal of Neurology. PMID 34919634 DOI: 10.1093/brain/awab452  0.134
2021 Kang SS, Ahn EH, Liu X, Bryson M, Miller GW, Weinshenker D, Ye K. ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease. Acta Neuropathologica. PMID 33895869 DOI: 10.1007/s00401-021-02315-1  0.132
2009 Hammerschmidt T, Terwel D, Kummer M, Weinshenker D, Gorji A, Hermann S, Schäfers M, Pape H, Heneka MT. P4-235: Norepinephrine deficiency aggravates learning and memory impairment independent of amyloid-beta levels in APP PS1 mice Alzheimer's & Dementia. 5: P499-P499. DOI: 10.1016/J.Jalz.2009.04.701  0.131
2022 De Oliveira PA, Moreno E, Casajuana-Martin N, Casadó-Anguera V, Cai NS, Camacho-Hernandez GA, Zhu H, Bonifazi A, Hall MD, Weinshenker D, Newman AH, Logothetis DE, Casadó V, Plant LD, Pardo L, et al. Preferential Gs protein coupling of the galanin Gal receptor in the µ-opioid-Gal receptor heterotetramer. Pharmacological Research. 182: 106322. PMID 35750299 DOI: 10.1016/j.phrs.2022.106322  0.127
2008 Hammerschmidt T, Kummer M, Gorji A, Terwel D, Weinshenker D, Pape H, Heneka M. Noradreneline deficiency aggrevates learning and memory impairment independent of Aß Levels in APPPS1 mice Aktuelle Neurologie. 35. DOI: 10.1055/S-0028-1086716  0.126
2023 Anderson T, Sharma S, Kelberman MA, Ware C, Guo N, Qin Z, Weinshenker D, Parent MB. Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline. Journal of Neurochemistry. PMID 37391269 DOI: 10.1111/jnc.15900  0.12
2023 Mei Z, Liu J, Schroeder JP, Weinshenker D, Duong DM, Seyfried NT, Li Y, Jin P, Wingo AP, Wingo TS. Lowering hippocampal miR-29a expression slows cognitive decline and reduces beta-amyloid deposition in 5xFAD mice. Research Square. PMID 37645711 DOI: 10.21203/rs.3.rs-3235257/v1  0.119
2023 Michaelides M, Levinstein M, De Oliveira P, Casajuana-Martin N, Quiroz C, Budinich R, Rais R, Rea W, Ventriglia E, Llopart N, Casadó-Anguera V, Moreno E, Walther D, Glatfelter G, Weinshenker D, et al. Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone. Research Square. PMID 36993715 DOI: 10.21203/rs.3.rs-2644719/v1  0.118
2023 Ehrenberg AJ, Kelberman MA, Liu KY, Dahl MJ, Weinshenker D, Falgàs N, Dutt S, Mather M, Ludwig M, Betts MJ, Winer JR, Teipel S, Weigand AJ, Eschenko O, Hämmerer D, et al. Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36642985 DOI: 10.1002/alz.12937  0.116
2023 McKay JL, Nye J, Goldstein FC, Sommerfeld B, Smith Y, Weinshenker D, Factor SA. Levodopa responsive freezing of gait is associated with reduced norepinephrine transporter binding in Parkinson's disease. Neurobiology of Disease. 179: 106048. PMID 36813207 DOI: 10.1016/j.nbd.2023.106048  0.111
2023 Mei Z, Liu J, Schroeder JP, Weinshenker D, Duong DM, Seyfried NT, Li Y, Jin P, Wingo AP, Wingo TS. Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice. Molecular Neurobiology. PMID 37989983 DOI: 10.1007/s12035-023-03791-0  0.107
2022 Cassidy CM, Therriault J, Pascoal TA, Cheung V, Savard M, Tuominen L, Chamoun M, McCall A, Celebi S, Lussier F, Massarweh G, Soucy JP, Weinshenker D, Tardif C, Ismail Z, et al. Association of locus coeruleus integrity with Braak stage and neuropsychiatric symptom severity in Alzheimer's disease. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35177805 DOI: 10.1038/s41386-022-01293-6  0.101
1995 Grando SA, Zelickson BD, Kist DA, Weinshenker D, Bigliardi PL, Wendelschafer-Crabb G, Kennedy WR, Dahl MV. Keratinocyte muscarinic acetylcholine receptors: immunolocalization and partial characterization. The Journal of Investigative Dermatology. 104: 95-100. PMID 7528248 DOI: 10.1111/1523-1747.Ep12613582  0.097
2022 Kelberman MA, Weinshenker D. A novel link between locus coeruleus activity and amyloid-related cognitive decline. Trends in Neurosciences. PMID 35659415 DOI: 10.1016/j.tins.2022.05.006  0.093
2004 Liles LC, Kumar MA, Weinshenker D. Use of Gene-Specific Primer Cocktails for First-Strand cDNA Synthesis With a Reverse Transcriptase Kit American Biotechnology Laboratory. 22: 20-21.  0.038
2004 Liles LC, Weinshenker D, Kumar A, Jarrin A. Application of a gene-specific primer cocktail for first-strand cDNA synthesis with the cMasterRT System | Die verwendung eines genspezifischen primer-cocktails für die erststrang-cDNA synthese mit dem cMasterRT System Biospektrum. 10: 110-111.  0.026
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