Charles Askew, PhD - Publications

Affiliations: 
2008-2015 Neuroscience University of Virginia, Charlottesville, VA 
 2011-2015 Otolaryngology Harvard - Boston Children's Hospital 
 2015- Gene Therapy Center University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Sensory Neuroscience

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS. Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c. Nature Biotechnology. PMID 28165476 DOI: 10.1038/nbt.3801  1
2017 Landegger LD, Pan B, Askew C, Wassmer SJ, Gluck SD, Galvin A, Taylor R, Forge A, Stankovic KM, Holt JR, Vandenberghe LH. A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear. Nature Biotechnology. PMID 28165475 DOI: 10.1038/nbt.3781  1
2015 Askew C, Rochat C, Pan B, Asai Y, Ahmed H, Child E, Schneider BL, Aebischer P, Holt JR. Tmc gene therapy restores auditory function in deaf mice. Science Translational Medicine. 7: 295ra108. PMID 26157030 DOI: 10.1126/scitranslmed.aab1996  1
2014 Zou J, Zheng T, Ren C, Askew C, Liu XP, Pan B, Holt JR, Wang Y, Yang J. Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice. Human Molecular Genetics. 23: 2374-90. PMID 24334608 DOI: 10.1093/hmg/ddt629  1
2012 Geng R, Melki S, Chen DH, Tian G, Furness DN, Oshima-Takago T, Neef J, Moser T, Askew C, Horwitz G, Holt JR, Imanishi Y, Alagramam KN. The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9485-98. PMID 22787034 DOI: 10.1523/JNEUROSCI.0311-12.2012  1
2011 Collado MS, Thiede BR, Baker W, Askew C, Igbani LM, Corwin JT. The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11855-66. PMID 21849546 DOI: 10.1523/JNEUROSCI.2525-11.2011  1
2009 Zallocchi M, Meehan DT, Delimont D, Askew C, Garige S, Gratton MA, Rothermund-Franklin CA, Cosgrove D. Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors. Hearing Research. 255: 109-20. PMID 19539019 DOI: 10.1016/j.heares.2009.06.006  1
2005 Gratton MA, Rao VH, Meehan DT, Askew C, Cosgrove D. Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: implications for capillary basement membrane pathology. The American Journal of Pathology. 166: 1465-74. PMID 15855646 DOI: 10.1016/S0002-9440(10)62363-2  1
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