| Year |
Citation |
Score |
| 2022 |
Alteen MG, Peacock H, Meek RW, Busmann JA, Zhu S, Davies GJ, Suga H, Vocadlo DJ. Potent De Novo Macrocyclic Peptides that Inhibit O-GlcNAc Transferase Through an Allosteric Mechanism. Angewandte Chemie (International Ed. in English). PMID 36460613 DOI: 10.1002/anie.202215671 |
0.306 |
|
| 2022 |
Dai SA, Hu Q, Gao R, Blythe EE, Touhara KK, Peacock H, Zhang Z, von Zastrow M, Suga H, Shokat KM. State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides. Cell. PMID 36170854 DOI: 10.1016/j.cell.2022.09.019 |
0.395 |
|
| 2021 |
Peacock H, Suga H. Discovery of De Novo Macrocyclic Peptides by Messenger RNA Display. Trends in Pharmacological Sciences. PMID 33771353 DOI: 10.1016/j.tips.2021.02.004 |
0.378 |
|
| 2020 |
Peacock H, Henriques ST, Benfield AH, Elliott AG, Luo J, Luccarelli J, Nagano M, Craik DJ, Hamilton AD. Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis and activity. Chemmedchem. PMID 32754982 DOI: 10.1002/Cmdc.202000474 |
0.563 |
|
| 2020 |
Troeira Henriques S, Peacock H, Benfield AH, Wang CK, Craik D. Challenging the Chirality Paradigm in Peptide-Lipid Interactions Biophysical Journal. 118: 343a. DOI: 10.1016/J.Bpj.2019.11.1983 |
0.409 |
|
| 2019 |
Troeira Henriques S, Peacock H, Benfield A, Wang CK, Craik DJ. Is the mirror image a true reflection? Intrinsic membrane chirality modulates peptide binding. Journal of the American Chemical Society. PMID 31765148 DOI: 10.1021/Jacs.9B11194 |
0.436 |
|
| 2017 |
Craik DJ, Lee MH, Rehm FBH, Tombling B, Doffek B, Peacock H. Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic & Medicinal Chemistry. PMID 28818463 DOI: 10.1016/J.Bmc.2017.08.005 |
0.445 |
|
| 2016 |
Peacock H, Luo J, Yamashita T, Luccarelli J, Thompson S, Hamilton AD. Non-covalent S···O interactions control conformation in a scaffold that disrupts islet amyloid polypeptide fibrillation. Chemical Science. 7: 6435-6439. PMID 28451100 DOI: 10.1039/C6Sc00756B |
0.515 |
|
| 2016 |
Peacock H, Thinnes CC, Kawamura A, Hamilton AD. Tetracyanoresorcin[4]arene selectively recognises trimethyllysine and inhibits its enzyme-catalysed demethylation Supramolecular Chemistry. 1-7. DOI: 10.1080/10610278.2016.1140898 |
0.509 |
|
| 2012 |
Ibarra-Soza JM, Morris AA, Jayalath P, Peacock H, Conrad WE, Donald MB, Kurth MJ, Beal PA. 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & Biomolecular Chemistry. 10: 6491-7. PMID 22766576 DOI: 10.1039/C2Ob25647A |
0.331 |
|
| 2011 |
Peacock H, Kannan A, Beal PA, Burrows CJ. Chemical modification of siRNA bases to probe and enhance RNA interference Journal of Organic Chemistry. 76: 7295-7300. PMID 21834582 DOI: 10.1021/Jo2012225 |
0.326 |
|
| 2011 |
Peacock H, Bachu R, Beal PA. Covalent stabilization of a small molecule-RNA complex Bioorganic and Medicinal Chemistry Letters. 21: 5002-5005. PMID 21601451 DOI: 10.1016/J.Bmcl.2011.04.136 |
0.382 |
|
| 2010 |
Peacock H, Fostvedt E, Beal PA. Minor-groove-modulating adenosine replacements control protein binding and RNAi activity in siRNAs Acs Chemical Biology. 5: 1115-1124. PMID 20863128 DOI: 10.1021/Cb100245U |
0.36 |
|
| 2010 |
Peacock H, Maydanovych O, Beal PA. N2-Modified 2-aminopurine ribonucleosides as minor-groove-modulating adenosine replacements in duplex RNA Organic Letters. 12: 1044-1047. PMID 20108910 DOI: 10.1021/Ol100019R |
0.326 |
|
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