Year |
Citation |
Score |
2023 |
Ko B, Jang Y, Kim MH, Lam TT, Seo HK, Jeong P, Choi M, Kang KW, Lee SD, Park JH, Kim M, Han SY, Kim YC. Discovery of benzimidazole-indazole derivatives as potent FLT3-tyrosine kinase domain mutant kinase inhibitors for acute myeloid leukemia. European Journal of Medicinal Chemistry. 262: 115860. PMID 37866334 DOI: 10.1016/j.ejmech.2023.115860 |
0.335 |
|
2022 |
Lee JH, Shin JE, Kim W, Jeong P, Kim MJ, Oh SJ, Lee HJ, Park HW, Han SY, Kim YC. Discovery of indirubin-3'-aminooxy-acetamide derivatives as potent and selective FLT3/D835Y mutant kinase inhibitors for acute myeloid leukemia. European Journal of Medicinal Chemistry. 237: 114356. PMID 35489222 DOI: 10.1016/j.ejmech.2022.114356 |
0.336 |
|
2022 |
Lee HJ, Moon Y, Choi J, Heo JD, Kim S, Nallapaneni HK, Chin YW, Lee J, Han SY. Characterization of KRC-108 as a TrkA Kinase Inhibitor with Anti-Tumor Effects. Biomolecules & Therapeutics. PMID 35264466 DOI: 10.4062/biomolther.2021.195 |
0.436 |
|
2021 |
Lee HJ, Jeong P, Moon Y, Choi J, Heo JD, Kim YC, Han SY. Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer. Pharmaceuticals (Basel, Switzerland). 14. PMID 33419162 DOI: 10.3390/ph14010038 |
0.343 |
|
2019 |
Yoon KB, Lee HJ, Chung HJ, Lee J, Choi J, Heo JD, Kim YC, Han SY. Discovery of LDD-1075 as a potent FLT3 inhibitor. Oncology Letters. 17: 4735-4741. PMID 30944659 DOI: 10.3892/Ol.2019.10096 |
0.389 |
|
2018 |
Ndolo KM, An SJ, Park KR, Lee HJ, Yoon KB, Kim YC, Han SY. Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with Anti-Tumor Effects. Biomolecules & Therapeutics. PMID 30060294 DOI: 10.4062/Biomolther.2018.091 |
0.369 |
|
2018 |
Lee HJ, Lee J, Jeong P, Choi J, Baek J, Ahn SJ, Moon Y, Heo JD, Choi YH, Chin YW, Kim YC, Han SY. Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia. Oncotarget. 9: 924-936. PMID 29416667 DOI: 10.18632/oncotarget.23221 |
0.32 |
|
2017 |
Lee CS, Baek J, Han SY. The Role of Kinase Modulators in Cellular Senescence for Use in Cancer Treatment. Molecules (Basel, Switzerland). 22. PMID 28841181 DOI: 10.3390/molecules22091411 |
0.306 |
|
2017 |
Yoon KB, Cho SY, An SJ, Park KR, Lee HJ, Yoon HS, Lee SM, Kim YC, Han SY. Characterization of the aminopyridine derivative KRC-180 as a JAK2 inhibitor. Oncology Letters. 14: 1347-1354. PMID 28789350 DOI: 10.3892/ol.2017.6353 |
0.412 |
|
2017 |
Ndolo KM, Park KR, Lee HJ, Yoon KB, Kim YC, Han SY. Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells. Immune Network. 17: 110-115. PMID 28458622 DOI: 10.4110/in.2017.17.2.110 |
0.361 |
|
2016 |
Yoon KB, Park KR, Kim SY, Han SY. Induction of Nuclear Enlargement and Senescence by Sirtuin Inhibitors in Glioblastoma Cells. Immune Network. 16: 183-8. PMID 27340387 DOI: 10.4110/in.2016.16.3.183 |
0.33 |
|
2015 |
Chung HJ, Park KR, Lee HJ, Lee J, Kim JH, Kim YC, Han SY. Effects of KRC-108 on the Aurora A activity and growth of colorectal cancer cells. Biochemical and Biophysical Research Communications. 461: 605-11. PMID 25912878 DOI: 10.1016/J.Bbrc.2015.04.073 |
0.347 |
|
2014 |
Chung HJ, Kamli MR, Lee HJ, Ha JD, Cho SY, Lee J, Kong JY, Han SY. Discovery of quinolinone derivatives as potent FLT3 inhibitors. Biochemical and Biophysical Research Communications. 445: 561-5. PMID 24530392 DOI: 10.1016/J.Bbrc.2014.02.029 |
0.315 |
|
2013 |
Choi G, Lee J, Ji JY, Woo J, Kang NS, Cho SY, Kim HR, Ha JD, Han SY. Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects. International Journal of Oncology. 43: 1205-11. PMID 23900402 DOI: 10.3892/Ijo.2013.2035 |
0.312 |
|
2013 |
Kim KC, Kim JW, Choi CS, Han SY, Cheong JH, Han SH, Yang SI, Bahn GH, Shin CY. A role of CPEB1 in the modulation of proliferation and neuronal maturation of rat primary neural progenitor cells. Neurochemical Research. 38: 1960-72. PMID 23824559 DOI: 10.1007/s11064-013-1102-4 |
0.351 |
|
2013 |
Chin YW, Kong JY, Han SY. Flavonoids as receptor tyrosine kinase FLT3 inhibitors Bioorganic and Medicinal Chemistry Letters. 23: 1768-1770. PMID 23411073 DOI: 10.1016/j.bmcl.2013.01.049 |
0.354 |
|
2012 |
Han SY, Lee CO, Ahn SH, Lee MO, Kang SY, Cha HJ, Cho SY, Ha JD, Ryu JW, Jung H, Kim HR, Koh JS, Lee J. Evaluation of a multi-kinase inhibitor KRC-108 as an anti-tumor agent in vitro and in vivo. Investigational New Drugs. 30: 518-23. PMID 21080208 DOI: 10.1007/S10637-010-9584-2 |
0.339 |
|
2010 |
Choi SJ, Moon MJ, Lee SD, Choi SU, Han SY, Kim YC. Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells. Bioorganic & Medicinal Chemistry Letters. 20: 2033-7. PMID 20153646 DOI: 10.1016/j.bmcl.2010.01.039 |
0.313 |
|
2008 |
Han SY. c-Jun N-Terminal Kinase Signaling Inhibitors Under Development. Toxicological Research. 24: 93-100. PMID 32038782 DOI: 10.5487/TR.2008.24.2.093 |
0.318 |
|
2006 |
Heasley LE, Han SY. JNK regulation of oncogenesis. Molecules and Cells. 21: 167-73. PMID 16682809 |
0.574 |
|
2005 |
Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, Bren-Mattison Y, Van Raay TJ, Nemenoff RA, Heasley LE. Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation. The Journal of Biological Chemistry. 280: 19625-34. PMID 15705594 DOI: 10.1074/Jbc.M409392200 |
0.555 |
|
2002 |
Han SY, Kim SH, Heasley LE. Differential gene regulation by specific gain-of-function JNK1 proteins expressed in Swiss 3T3 fibroblasts. The Journal of Biological Chemistry. 277: 47167-74. PMID 12354774 DOI: 10.1074/Jbc.M204270200 |
0.567 |
|
2002 |
Zentrich E, Han SY, Pessoa-Brandao L, Butterfield L, Heasley LE. Collaboration of JNKs and ERKs in nerve growth factor regulation of the neurofilament light chain promoter in PC12 cells. The Journal of Biological Chemistry. 277: 4110-8. PMID 11733514 DOI: 10.1074/Jbc.M107824200 |
0.582 |
|
2001 |
Van Putten V, Refaat Z, Dessev C, Blaine S, Wick M, Butterfield L, Han SY, Heasley LE, Nemenoff RA. Induction of cytosolic phospholipase A2 by oncogenic Ras is mediated through the JNK and ERK pathways in rat epithelial cells. The Journal of Biological Chemistry. 276: 1226-32. PMID 11042196 DOI: 10.1074/Jbc.M003581200 |
0.574 |
|
2000 |
Garat C, Van Putten V, Refaat ZA, Dessev C, Han SY, Nemenoff RA. Induction of smooth muscle alpha-actin in vascular smooth muscle cells by arginine vasopressin is mediated by c-Jun amino-terminal kinases and p38 mitogen-activated protein kinase. The Journal of Biological Chemistry. 275: 22537-43. PMID 10807920 DOI: 10.1074/Jbc.M003000200 |
0.417 |
|
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