| Year |
Citation |
Score |
| 2020 |
Peacock H, Henriques ST, Benfield AH, Elliott AG, Luo J, Luccarelli J, Nagano M, Craik DJ, Hamilton AD. Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis and activity. Chemmedchem. PMID 32754982 DOI: 10.1002/Cmdc.202000474 |
0.578 |
|
| 2020 |
Harvey EP, Hauseman ZJ, Cohen DT, Rettenmaier TJ, Lee S, Huhn AJ, Wales TE, Seo HS, Luccarelli J, Newman CE, Guerra RM, Bird GH, Dhe-Paganon S, Engen JR, Wells JA, et al. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chemical Biology. PMID 32413285 DOI: 10.1016/J.Chembiol.2020.04.004 |
0.354 |
|
| 2017 |
Luccarelli J, Jones IM, Thompson S, Hamilton AD. Unpicking the determinants of amide NHO[double bond, length as m-dash]C hydrogen bond strength with diphenylacetylene molecular balances. Organic & Biomolecular Chemistry. PMID 29058730 DOI: 10.1039/C7Ob02026K |
0.524 |
|
| 2017 |
Pritz JR, Wachter F, Lee S, Luccarelli J, Wales TE, Cohen DT, Coote P, Heffron GJ, Engen JR, Massefski W, Walensky LD. Allosteric sensitization of proapoptotic BAX. Nature Chemical Biology. PMID 28692068 DOI: 10.1038/Nchembio.2433 |
0.335 |
|
| 2016 |
Peacock H, Luo J, Yamashita T, Luccarelli J, Thompson S, Hamilton AD. Non-covalent S···O interactions control conformation in a scaffold that disrupts islet amyloid polypeptide fibrillation. Chemical Science. 7: 6435-6439. PMID 28451100 DOI: 10.1039/C6Sc00756B |
0.59 |
|
| 2016 |
Lee S, Wales TE, Escudero S, Cohen DT, Luccarelli J, Gallagher CG, Cohen NA, Huhn AJ, Bird GH, Engen JR, Walensky LD. Allosteric inhibition of antiapoptotic MCL-1. Nature Structural & Molecular Biology. PMID 27159560 DOI: 10.1038/Nsmb.3223 |
0.337 |
|
| 2016 |
Lee S, Wales TE, Gallagher C, Cohen DT, Escudero S, Luccarelli J, Huhn AJ, Cohen NA, Bird GH, Engen JR, Walensky LD. Abstract 3553: A novel allosteric mechanism for molecular inhibition of anti-apoptotic MCL-1 Cancer Research. 76: 3553-3553. DOI: 10.1158/1538-7445.Am2016-3553 |
0.339 |
|
| 2015 |
Edwards AL, Wachter F, Lammert M, Huhn AJ, Luccarelli J, Bird GH, Walensky LD. Cellular Uptake and Ultrastructural Localization Underlie the Pro-apoptotic Activity of a Hydrocarbon-stapled BIM BH3 Peptide. Acs Chemical Biology. PMID 26151238 DOI: 10.1021/Acschembio.5B00214 |
0.366 |
|
| 2015 |
Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proceedings of the National Academy of Sciences of the United States of America. 112: 1761-6. PMID 25624485 DOI: 10.1073/Pnas.1413185112 |
0.332 |
|
| 2013 |
Simister PC, Luccarelli J, Thompson S, Appella DH, Feller SM, Hamilton AD. Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen. Bioorganic & Medicinal Chemistry. 21: 4027-33. PMID 23182216 DOI: 10.1016/J.Bmc.2012.10.023 |
0.564 |
|
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