Darren Opland, Ph.D. - Publications

Yale University, New Haven, CT 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ter Horst KW, Lammers NM, Trinko R, Opland DM, Figee M, Ackermans MT, Booij J, van den Munckhof P, Schuurman PR, Fliers E, Denys D, DiLeone RJ, la Fleur SE, Serlie MJ. Striatal dopamine regulates systemic glucose metabolism in humans and mice. Science Translational Medicine. 10. PMID 29794060 DOI: 10.1126/Scitranslmed.Aar3752  0.32
2015 van den Heuvel JK, Furman K, Gumbs MC, Eggels L, Opland DM, Land BB, Kolk SM, S Narayanan N, Fliers E, Kalsbeek A, DiLeone RJ, la Fleur SE. Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. Biological Psychiatry. 77: 633-41. PMID 25109664 DOI: 10.1016/J.Biopsych.2014.06.008  0.32
2014 Wang L, Opland D, Tsai S, Luk CT, Schroer SA, Allison MB, Elia AJ, Furlonger C, Suzuki A, Paige CJ, Mak TW, Winer DA, Myers MG, Woo M. Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex. Nature Medicine. 20: 484-92. PMID 24747746 DOI: 10.1038/Nm.3527  0.32
2014 Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CW, Alonso LC, Myers MG, Jonas JC, Poitout V, Kulkarni RN, Mauvais-Jarvis F. The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes. Plos One. 9: e87941. PMID 24498408 DOI: 10.1371/Journal.Pone.0087941  0.32
2013 Opland D, Sutton A, Woodworth H, Brown J, Bugescu R, Garcia A, Christensen L, Rhodes C, Myers M, Leinninger G. Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity. Molecular Metabolism. 2: 423-34. PMID 24327958 DOI: 10.1016/J.Molmet.2013.07.008  0.32
2012 Elghazi L, Gould AP, Weiss AJ, Barker DJ, Callaghan J, Opland D, Myers M, Cras-Méneur C, Bernal-Mizrachi E. Importance of β-Catenin in glucose and energy homeostasis. Scientific Reports. 2: 693. PMID 23012647 DOI: 10.1038/Srep00693  0.32
2011 Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG. Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metabolism. 14: 313-23. PMID 21907138 DOI: 10.1016/J.Cmet.2011.06.016  0.32
2010 Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG, et al. Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Diabetes. 59: 3090-8. PMID 20802254 DOI: 10.2337/Db10-0624  0.32
2010 Opland DM, Leinninger GM, Myers MG. Modulation of the mesolimbic dopamine system by leptin. Brain Research. 1350: 65-70. PMID 20417193 DOI: 10.1016/J.Brainres.2010.04.028  0.32
2010 Leshan RL, Opland DM, Louis GW, Leinninger GM, Patterson CM, Rhodes CJ, Münzberg H, Myers MG. Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5713-23. PMID 20410123 DOI: 10.1523/Jneurosci.1001-10.2010  0.32
2010 Heinrich G, Ghosh S, Deangelis AM, Schroeder-Gloeckler JM, Patel PR, Castaneda TR, Jeffers S, Lee AD, Jung DY, Zhang Z, Opland DM, Myers MG, Kim JK, Najjar SM. Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice. Gastroenterology. 139: 644-52, 652.e1. PMID 20381490 DOI: 10.1053/J.Gastro.2010.03.056  0.32
2009 Mori H, Inoki K, Opland D, Münzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski DJ, Macdougald OA, Myers MG, Guan KL. Critical roles for the TSC-mTOR pathway in β-cell function. American Journal of Physiology. Endocrinology and Metabolism. 297: E1013-22. PMID 19690069 DOI: 10.1152/Ajpendo.00262.2009  0.32
2009 Leinninger GM, Jo YH, Leshan RL, Louis GW, Yang H, Barrera JG, Wilson H, Opland DM, Faouzi MA, Gong Y, Jones JC, Rhodes CJ, Chua S, Diano S, Horvath TL, et al. Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metabolism. 10: 89-98. PMID 19656487 DOI: 10.1016/J.Cmet.2009.06.011  0.32
2009 Mori H, Inoki K, Münzberg H, Opland D, Faouzi M, Villanueva EC, Ikenoue T, Kwiatkowski D, MacDougald OA, Myers MG, Guan KL. Critical role for hypothalamic mTOR activity in energy balance. Cell Metabolism. 9: 362-74. PMID 19356717 DOI: 10.1016/J.Cmet.2009.03.005  0.32
2006 He Z, Opland DM, Way KJ, Ueki K, Bodyak N, Kang PM, Izumo S, Kulkarni RN, Wang B, Liao R, Kahn CR, King GL. Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 787-93. PMID 16469952 DOI: 10.1161/01.Atv.0000209500.15801.4E  0.32
2005 He Z, Way KJ, Arikawa E, Chou E, Opland DM, Clermont A, Isshiki K, Ma RC, Scott JA, Schoen FJ, Feener EP, King GL. Differential regulation of angiotensin II-induced expression of connective tissue growth factor by protein kinase C isoforms in the myocardium. The Journal of Biological Chemistry. 280: 15719-26. PMID 15699040 DOI: 10.1074/Jbc.M413493200  0.32
2003 Jiang ZY, He Z, King BL, Kuroki T, Opland DM, Suzuma K, Suzuma I, Ueki K, Kulkarni RN, Kahn CR, King GL. Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis. The Journal of Biological Chemistry. 278: 31964-71. PMID 12775712 DOI: 10.1074/Jbc.M303314200  0.32
2002 Chou E, Suzuma I, Way KJ, Opland D, Clermont AC, Naruse K, Suzuma K, Bowling NL, Vlahos CJ, Aiello LP, King GL. Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue. Circulation. 105: 373-9. PMID 11804995 DOI: 10.1161/Hc0302.102143  0.32
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