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Nicoletta Savalli - Publications

Affiliations: 
2013- Dept. of Anesthesiology-Div.of Mol. Medicine University of California, Los Angeles, Los Angeles, CA 
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46/48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Servettini I, Talani G, Megaro A, Setzu MD, Biggio F, Briffa M, Guglielmi L, Savalli N, Binda F, Delicata F, Bru-Mercier G, Vassallo N, Maglione V, Cauchi RJ, Di Pardo A, et al. An activator of voltage-gated K channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207978120. PMID 37487086 DOI: 10.1073/pnas.2207978120  0.695
2023 Medzikovic L, Aryan L, Ruffenach G, Li M, Savalli N, Sun W, Sarji S, Hong J, Sharma S, Olcese R, Fishbein G, Eghbali M. Myocardial fibrosis and calcification are attenuated by microRNA-129-5p targeting Asporin and Sox9 in cardiac fibroblasts. Jci Insight. 8. PMID 37154157 DOI: 10.1172/jci.insight.168655  0.465
2021 Angelini M, Pezhouman A, Savalli N, Chang MG, Steccanella F, Scranton K, Calmettes G, Ottolia M, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. Suppression of ventricular arrhythmias by targeting late L-type Ca2+ current. The Journal of General Physiology. 153. PMID 34698805 DOI: 10.1085/jgp.202012584  0.8
2021 Savalli N, Angelini M, Steccanella F, Wier J, Wu F, Quinonez M, DiFranco M, Neely A, Cannon SC, Olcese R. The distinct role of the four voltage sensors of the skeletal CaV1.1 channel in voltage-dependent activation. The Journal of General Physiology. 153. PMID 34546289 DOI: 10.1085/jgp.202112915  0.839
2020 Savalli N, Angelini M, Steccanella F, Wu F, Quinonez M, Neely A, Cannon SC, Olcese R. The Contribution of the Individual Voltage Sensors to the Activation of Skeletal CaV1.1 Channels Biophysical Journal. 118: 105a. DOI: 10.1016/J.Bpj.2019.11.728  0.819
2020 Angelini M, Pezhouman A, Savalli N, Chang M, Calmettes G, Steccanella F, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. Potent Suppression of Ventricular Arrhythmias by Selectively Targeting Late L-type Calcium Current Biophysical Journal. 118: 104a. DOI: 10.1016/J.Bpj.2019.11.723  0.76
2020 Steccanella F, Savalli N, Angelini M, Neely A, Olcese R. Differential Modulation of L-Type CaV1.1 and CaV1.2 Channels by the α2δ-1 Subunit Biophysical Journal. 118: 499a. DOI: 10.1016/J.Bpj.2019.11.2754  0.814
2020 Angelini M, Savalli N, Steccanella F, Di Franco MG, Neely A, Cannon SC, Olcese R. Which CaV1.1 Voltage Sensor(s) Activate RYR1? Biophysical Journal. 118: 498a. DOI: 10.1016/J.Bpj.2019.11.2752  0.773
2019 Steccanella F, Savalli N, Yusifov T, Battista Luciani G, Neely A, Olcese R. How Does the α2δ-1 Subunit Modulate Skeletal CaV1.1 Channels? Biophysical Journal. 116: 113a. DOI: 10.1016/J.Bpj.2018.11.639  0.829
2019 Angelini M, Savalli N, Yusifov T, Olcese R. Skeletal γ1 Subunit Modulation of Human CaV1.1 and CaV1.2 Channels Biophysical Journal. 116: 112a-113a. DOI: 10.1016/J.Bpj.2018.11.637  0.831
2019 Savalli N, Wu F, Quinonez M, Cannon SC, Olcese R. A Mutation Linked to Malignant Hyperthermia in the Skeletal CaV1.1 Channel Stabilizes the Resting State of Voltage Sensor I and Impairs Channel Activation Biophysical Journal. 116: 111a. DOI: 10.1016/J.Bpj.2018.11.629  0.733
2018 Angelini M, Pezhouman A, Chang MG, Savalli N, Calmettes G, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. L-Type Calcium Channel Gating Modifiers as a New Class of Antiarrhythmic Drugs Biophysical Journal. 114: 623a. DOI: 10.1016/J.Bpj.2017.11.3370  0.821
2018 Savalli N, Wu F, Quinonez M, Cannon SC, Olcese R. Optically-Tracked Structural Rearrangements of the Voltage Sensing Domains in the Human CaV1.1 Channel Biophysical Journal. 114: 39a. DOI: 10.1016/J.Bpj.2017.11.265  0.686
2017 Yusifov T, Savalli N, Pantazis A, Heinemann SH, Hoshi T, Olcese R. Carbon Monoxide May Regulate BK slo1 Channel Activity by Partially Disrupting Heme Coordination Biophysical Journal. 112: 112a. DOI: 10.1016/J.Bpj.2016.11.631  0.759
2017 Contreras GF, Savalli N, Pantazis A, Gonzalez C, Olcese R, Neely A. The Calcium Channel A2D Subunit Increases the Gating Charges of Ca v 1.2 Channels Biophysical Journal. 112: 108a. DOI: 10.1016/J.Bpj.2016.11.614  0.818
2017 Angelini M, Pezhouman A, Savalli N, Pantazis A, Karagueuzian HS, Weiss JN, Olcese R. A New Class of Antiarrhythmics for Late I CA,L Biophysical Journal. 112: 234a-235a. DOI: 10.1016/J.Bpj.2016.11.1285  0.808
2016 Savalli N, Pantazis A, Sigg D, Weiss JN, Neely A, Olcese R. The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials. The Journal of General Physiology. 148: 147-59. PMID 27481713 DOI: 10.1085/Jgp.201611586  0.836
2016 Savalli N, Angelini M, Weiss JN, Olcese R. Gabapentinoids Suppress Early Afterdepolarizations by Uncoupling α2δ-1 Subunits from CAV1.2 Channels: Implications for CAV Channel Gating-Modifiers as a New Class of Antiarrhythmics Biophysical Journal. 110: 34a. DOI: 10.1016/J.Bpj.2015.11.252  0.865
2016 De Giorgis D, Contreras G, Savalli N, Navarro-Quezada N, Gonzalez C, Olcese R, Neely A. Regulation of Voltage Sensing Structures of CaV1.2 Calcium Channels by the Auxiliary β-Subunit (β3) Biophysical Journal. 110: 444a. DOI: 10.1016/J.Bpj.2015.11.2390  0.747
2016 Savalli N, Angelini M, Pantazis A, Yusifov T, Neely A, Olcese R. Eminence of VSD I in the Voltage-Dependent Inactivation of the Human CaV1.2 Channel Biophysical Journal. 110: 444a. DOI: 10.1016/J.Bpj.2015.11.2388  0.853
2016 Angelini M, Pezhouman A, Savalli N, Pantazis A, Melkonian A, Weiss JN, Karagueuzian HS, Olcese R. Roscovitine as the Archetypal Member of a Novel Class of Antiarrhythmics Targeting Late ICa,L Biophysical Journal. 110: 272a. DOI: 10.1016/J.Bpj.2015.11.1478  0.791
2015 Yusifov T, Savalli N, Heinemann SH, Hoshi T, Olcese R. The Heme-Bound Human BK Channel Gating Ring is a Co Sensor Biophysical Journal. 108: 122a. DOI: 10.1016/J.Bpj.2014.11.682  0.71
2015 Yusifov T, Savalli N, Park S, Pantazis A, Olcese R. The Role of Met-691 in Heme-Dependent Regulation Supports the Presence of a Cytochrome-C-Like Structure in Human BK Channels Biophysical Journal. 108: 121a-122a. DOI: 10.1016/J.Bpj.2014.11.681  0.793
2015 Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. The α2δ Subunit Efficiently Couples VSDs Activation to Pore Opening in Human Cav1.2 Channels Biophysical Journal. 108: 581a. DOI: 10.1016/J.Bpj.2014.11.3173  0.82
2015 Savalli N, Sigg D, Neely A, Olcese R. β2A and β3 Differentially Modulate Time- and Voltage-Dependent Properties of Individual Voltage Sensors in the Human Cav1.2 Channel Biophysical Journal. 108: 581a. DOI: 10.1016/J.Bpj.2014.11.3172  0.702
2014 Peretti M, Angelini M, Savalli N, Florio T, Yuspa SH, Mazzanti M. Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets. Biochimica Et Biophysica Acta. PMID 25546839 DOI: 10.1016/J.Bbamem.2014.12.012  0.803
2014 Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proceedings of the National Academy of Sciences of the United States of America. 111: 18381-6. PMID 25489110 DOI: 10.1073/Pnas.1411127112  0.822
2014 Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. The α2δ Subunit Facilitates CaV1.2 Channel Activation by Remodeling Its Four Voltage Sensor Domains Biophysical Journal. 106: 135a. DOI: 10.1016/J.Bpj.2013.11.791  0.826
2014 Sigg D, Shieh R, Pantazis A, Savalli N, Olcese R. Hill Analysis of Ion Channel Activation: Theory and Practice Biophysical Journal. 106: 134a-135a. DOI: 10.1016/J.Bpj.2013.11.789  0.752
2014 Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. The Functional Heterogeneity of the Human CaV1.2 Voltage Sensors Biophysical Journal. 106: 134a. DOI: 10.1016/J.Bpj.2013.11.786  0.781
2014 Yusifov T, Savalli N, Pantazis A, Olcese R. Enzymatic Activity of the Human BK Channel: A Function Beyond Electrical Signaling Biophysical Journal. 106: 535a. DOI: 10.1016/J.Bpj.2013.11.2986  0.786
2014 Savalli N, Pantazis A, Sigg D, Neely A, Olcese R. A Timothy Syndrome Causing Mutation Perturbs Voltage Sensor Operation in Human CaV1.2 Channels Biophysical Journal. 106: 330a-331a. DOI: 10.1016/J.Bpj.2013.11.1898  0.819
2013 Setti M, Savalli N, Osti D, Richichi C, Angelini M, Brescia P, Fornasari L, Carro MS, Mazzanti M, Pelicci G. Functional role of CLIC1 ion channel in glioblastoma-derived stem/progenitor cells. Journal of the National Cancer Institute. 105: 1644-55. PMID 24115360 DOI: 10.1093/Jnci/Djt278  0.753
2013 Averaimo S, Abeti R, Savalli N, Brown LJ, Curmi PM, Breit SN, Mazzanti M. Point mutations in the transmembrane region of the clic1 ion channel selectively modify its biophysical properties. Plos One. 8: e74523. PMID 24058583 DOI: 10.1371/Journal.Pone.0074523  0.511
2013 Savalli N, Sun X, Peskoff A, Yazejian B, Olcese R, Grinnell AD. Using CaV-Type Dependent BK Channel Behavior to Probe BK-CaV Channel Coupling and Submembrane [Ca2+] Dynamics Biophysical Journal. 104: 471a. DOI: 10.1016/J.Bpj.2012.11.2601  0.754
2013 Pantazis A, Savalli N, Neely A, Olcese R. Optically-Resolved Conformational Rearrangements of the Voltage-Sensing Domains of the Human CaV1.2 Channel Biophysical Journal. 104: 358a-359a. DOI: 10.1016/J.Bpj.2012.11.1992  0.816
2013 Pantazis A, Savalli N, Olcese R. The Activation Transition of the Human BK (Slo1) Voltage Sensor Involves a Complex Rearrangement of its Helix Bundle as Resolved by Site-Directed Fluorophore/Quencher Pairs Biophysical Journal. 104: 197a. DOI: 10.1016/J.Bpj.2012.11.1112  0.77
2012 Savalli N, Pantazis A, Yusifov T, Sigg D, Olcese R. The contribution of RCK domains to human BK channel allosteric activation. The Journal of Biological Chemistry. 287: 21741-50. PMID 22556415 DOI: 10.1074/Jbc.M112.346171  0.777
2012 Savalli N, Kohanteb AP, Yazejian B, Olcese R, Peskoff A, Grinnell AD. BK and CaV Channel Interactions in the Plasma Membrane Biophysical Journal. 102: 687a. DOI: 10.1016/J.Bpj.2011.11.3736  0.758
2012 Savalli N, Angelini M, Setti M, Osti D, Pelicci G, Mazzanti M. CLIC1 Functional Expression in the Plasma Membrane Correlates with Human Glioblastoma Aggressiveness Biophysical Journal. 102: 550a. DOI: 10.1016/J.Bpj.2011.11.3000  0.744
2010 Pantazis A, Gudzenko V, Savalli N, Sigg D, Olcese R. Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 107: 4459-64. PMID 20160086 DOI: 10.1073/Pnas.0911959107  0.803
2009 Pantazis A, Gudzenko V, Savalli N, Kohanteb A, Sigg D, Olcese R. Cooperativity Between Voltage-sensing Domains in the Human BK Channel Revealed by Voltage-clamp Fluorometry. Biophysical Journal. 96: 481a. DOI: 10.1016/J.Bpj.2008.12.2480  0.793
2008 Yusifov T, Savalli N, Gandhi CS, Ottolia M, Olcese R. The RCK2 domain of the human BKCa channel is a calcium sensor. Proceedings of the National Academy of Sciences of the United States of America. 105: 376-81. PMID 18162557 DOI: 10.1073/Pnas.0705261105  0.666
2007 Savalli N, Kondratiev A, de Quintana SB, Toro L, Olcese R. Modes of operation of the BKCa channel beta2 subunit. The Journal of General Physiology. 130: 117-31. PMID 17591990 DOI: 10.1085/Jgp.200709803  0.73
2007 Gudzenko V, Shiferaw Y, Savalli N, Vyas R, Weiss JN, Olcese R. Influence of channel subunit composition on L-type Ca2+ current kinetics and cardiac wave stability. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1805-15. PMID 17545475 DOI: 10.1152/Ajpheart.01160.2006  0.672
2006 Savalli N, Kondratiev A, Toro L, Olcese R. Voltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry. Proceedings of the National Academy of Sciences of the United States of America. 103: 12619-24. PMID 16895996 DOI: 10.1073/Pnas.0601176103  0.742
Low-probability matches (unlikely to be authored by this person)
2006 Pessina A, Croera C, Savalli N, Bonomi A, Cavicchini L, Turlizzi E, Guizzardi F, Guido L, Daprai L, Neri MG. Bcl-2 down modulation in WEHI-3B/CTRES cells resistant to Cholera Toxin (CT)-induced apoptosis. Cell Research. 16: 306-12. PMID 16541129 DOI: 10.1038/Sj.Cr.7310038  0.235
2004 Pessina A, Eletti B, Croera C, Savalli N, Diodovich C, Gribaldo L. Pancreas developing markers expressed on human mononucleated umbilical cord blood cells. Biochemical and Biophysical Research Communications. 323: 315-22. PMID 15351739 DOI: 10.1016/J.Bbrc.2004.08.088  0.223
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