| Year |
Citation |
Score |
| 2023 |
Goth CK, Mehta AY, McQuillan AM, Baker KJ, Hanes MS, Park SS, Stavenhagen K, Hjortø GM, Heimburg-Molinaro J, Chaikof EL, Rosenkilde MM, Cummings RD. Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation. Cell Chemical Biology. PMID 37463583 DOI: 10.1016/j.chembiol.2023.06.013 |
0.301 |
|
| 2016 |
Mangrum JB, Mehta AY, Alabbas AB, Desai UR, Hawkridge AM. Comparative analysis of INLIGHT™-labeled enzymatically depolymerized heparin by reverse-phase chromatography and high-performance mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 27888308 DOI: 10.1007/s00216-016-0055-2 |
0.697 |
|
| 2016 |
Verespy Iii S, Mehta AY, Afosah D, Al-Horani RA, Desai UR. Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin. Scientific Reports. 6: 24043. PMID 27053426 DOI: 10.1038/Srep24043 |
0.777 |
|
| 2016 |
Mehta AY, Mohammed BM, Martin EJ, Brophy DF, Gailani D, Desai UR. Allosterism-based Simultaneous, Dual Anticoagulant and Antiplatelet Action Allosteric Inhibitor Targeting the Glycoprotein Ibα and Heparin-Binding Site of Thrombin. Journal of Thrombosis and Haemostasis : Jth. PMID 26748875 DOI: 10.1111/Jth.13254 |
0.67 |
|
| 2015 |
Boothello RS, Sarkar A, Tran VM, Nguyen TK, Sankaranarayanan NV, Mehta AY, Alabbas A, Brown S, Rossi A, Joice AC, Mencio CP, Quintero MV, Kuberan B, Desai UR. Chemoenzymatically Prepared Heparan Sulfate Containing Rare 2-O-Sulfonated Glucuronic Acid Residues. Acs Chemical Biology. 10: 1485-94. PMID 25742429 DOI: 10.1021/Acschembio.5B00071 |
0.702 |
|
| 2014 |
Mehta AY, Desai UR. Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2. Biochemical and Biophysical Research Communications. 452: 813-6. PMID 25201728 DOI: 10.1016/j.bbrc.2014.09.003 |
0.625 |
|
| 2014 |
Argade MD, Mehta AY, Sarkar A, Desai UR. Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors. Journal of Medicinal Chemistry. 57: 3559-69. PMID 24666186 DOI: 10.1021/Jm5002698 |
0.816 |
|
| 2014 |
Mehta AY, Thakkar JN, Mohammed BM, Martin EJ, Brophy DF, Kishimoto T, Desai UR. Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects. Journal of Medicinal Chemistry. 57: 3030-9. PMID 24635452 DOI: 10.1021/Jm4020026 |
0.797 |
|
| 2014 |
Mehta AY, Jin Y, Desai UR. An update on recent patents on thrombin inhibitors (2010 - 2013). Expert Opinion On Therapeutic Patents. 24: 47-67. PMID 24099091 DOI: 10.1517/13543776.2014.845169 |
0.593 |
|
| 2013 |
Sidhu PS, Abdel Aziz MH, Sarkar A, Mehta AY, Zhou Q, Desai UR. Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition. Journal of Medicinal Chemistry. 56: 5059-70. PMID 23718540 DOI: 10.1021/Jm400369Q |
0.72 |
|
| 2013 |
Al-Horani RA, Ponnusamy P, Mehta AY, Gailani D, Desai UR. Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa. Journal of Medicinal Chemistry. 56: 867-78. PMID 23316863 DOI: 10.1021/Jm301338Q |
0.802 |
|
| 2012 |
Al-Horani RA, Mehta AY, Desai UR. Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold. European Journal of Medicinal Chemistry. 54: 771-83. PMID 22770607 DOI: 10.1016/J.Ejmech.2012.06.032 |
0.785 |
|
| 2011 |
Desai BJ, Boothello RS, Mehta AY, Scarsdale JN, Wright HT, Desai UR. Interaction of thrombin with sucrose octasulfate. Biochemistry. 50: 6973-82. PMID 21736375 DOI: 10.1021/Bi2004526 |
0.784 |
|
| 2011 |
Sidhu PS, Liang A, Mehta AY, Abdel Aziz MH, Zhou Q, Desai UR. Rational design of potent, small, synthetic allosteric inhibitors of thrombin. Journal of Medicinal Chemistry. 54: 5522-31. PMID 21714536 DOI: 10.1021/Jm2005767 |
0.741 |
|
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