Michael V. Sofroniew - Publications

Neurobiology University of California, Los Angeles, Los Angeles, CA 
neural repair

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV. Author Correction: Divergent transcriptional regulation of astrocyte reactivity across disorders. Nature. PMID 36977770 DOI: 10.1038/s41586-023-05975-z  0.736
2022 Cheng Y, Yin Y, Zhang A, Bernstein AM, Kawaguchi R, Gao K, Potter K, Gilbert HY, Ao Y, Ou J, Fricano-Kugler CJ, Goldberg JL, He Z, Woolf CJ, Sofroniew MV, et al. Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice. Nature Communications. 13: 4418. PMID 35906210 DOI: 10.1038/s41467-022-31960-7  0.304
2022 Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV. Divergent transcriptional regulation of astrocyte reactivity across disorders. Nature. PMID 35614216 DOI: 10.1038/s41586-022-04739-5  0.747
2022 Wahane S, Sofroniew MV. Correction to: Loss‑of‑function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation. Cell and Tissue Research. PMID 35366111 DOI: 10.1007/s00441-022-03617-w  0.772
2021 Wahane S, Sofroniew MV. Review article for CTR special issue edited by C. Schachtrup Title of Special Issue: "Modulating scar formation for improving brain repair" Loss-of-function manipulations to identify roles of diverse glia and stromal cells during CNS scar formation. Cell and Tissue Research. PMID 34164732 DOI: 10.1007/s00441-021-03487-8  0.791
2020 Sofroniew MV. Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity. Trends in Immunology. 41: 758-770. PMID 32819810 DOI: 10.1016/j.it.2020.07.004  0.398
2019 Tassoni A, Farkhondeh V, Itoh Y, Itoh N, Sofroniew MV, Voskuhl RR. The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression. Scientific Reports. 9: 10010. PMID 31292459 DOI: 10.1038/S41598-019-46232-6  0.324
2019 Liddelow SA, Sofroniew MV. Astrocytes usurp neurons as a disease focus. Nature Neuroscience. PMID 30858602 DOI: 10.1038/S41593-019-0367-6  0.392
2018 Sofroniew MV. Stem-Cell-Derived Astrocytes Divulge Secrets of Mutant GFAP. Cell Stem Cell. 23: 630-631. PMID 30388417 DOI: 10.1016/j.stem.2018.10.020  0.344
2018 Anderson MA, O'Shea TM, Burda JE, Ao Y, Barlatey SL, Bernstein AM, Kim JH, James ND, Rogers A, Kato B, Wollenberg AL, Kawaguchi R, Coppola G, Wang C, Deming TJ, ... ... Sofroniew MV, et al. Required growth facilitators propel axon regeneration across complete spinal cord injury. Nature. PMID 30158698 DOI: 10.1038/S41586-018-0467-6  0.76
2018 Sofroniew MV. Dissecting spinal cord regeneration. Nature. 557: 343-350. PMID 29769671 DOI: 10.1038/s41586-018-0068-4  0.314
2018 Wollenberg AL, O'Shea TM, Kim JH, Czechanski A, Reinholdt LG, Sofroniew MV, Deming TJ. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. Biomaterials. 178: 527-545. PMID 29657091 DOI: 10.1016/J.Biomaterials.2018.03.057  0.357
2017 Itoh N, Itoh Y, Tassoni A, Ren E, Kaito M, Ohno A, Ao Y, Farkhondeh V, Johnsonbaugh H, Burda J, Sofroniew MV, Voskuhl RR. Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279367 DOI: 10.1073/Pnas.1716032115  0.359
2017 O'Shea TM, Burda JE, Sofroniew MV. Cell biology of spinal cord injury and repair. The Journal of Clinical Investigation. PMID 28737515 DOI: 10.1172/Jci90608  0.78
2017 Horng S, Therattil A, Moyon S, Gordon A, Kim K, Argaw AT, Hara Y, Mariani JN, Sawai S, Flodby P, Crandall ED, Borok Z, Sofroniew MV, Chapouly C, John GR. Astrocytic tight junctions control inflammatory CNS lesion pathogenesis. The Journal of Clinical Investigation. PMID 28737509 DOI: 10.1172/Jci91301  0.354
2017 Burda JE, Sofroniew MV. Seducing astrocytes to the dark side. Cell Research. PMID 28303889 DOI: 10.1038/Cr.2017.37  0.778
2017 Tamm ER, Ethier CR, Burgoyne C, Ethier CR, Tamm ER, Stowell C, Dowling JE, Downs C, Ellisman MH, Fisher S, Fortune B, Fruttiger M, Jakobs T, Lewis G, ... ... Sofroniew M, et al. Biological aspects of axonal damage in glaucoma: A brief review. Experimental Eye Research. PMID 28223179 DOI: 10.1016/J.Exer.2017.02.006  0.329
2017 Ren Y, Ao Y, O'Shea TM, Burda JE, Bernstein AM, Brumm AJ, Muthusamy N, Ghashghaei HT, Carmichael ST, Cheng L, Sofroniew MV. Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. Scientific Reports. 7: 41122. PMID 28117356 DOI: 10.1038/Srep41122  0.768
2016 Xu J, Bernstein AM, Wong A, Lu XH, Khoja S, Yang XW, Davies DL, Micevych P, Sofroniew MV, Khakh BS. P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8902-20. PMID 27559172 DOI: 10.1523/Jneurosci.1496-16.2016  0.382
2016 Anderson MA, Burda JE, Ren Y, Ao Y, O'Shea TM, Kawaguchi R, Coppola G, Khakh BS, Deming TJ, Sofroniew MV. Astrocyte scar formation aids central nervous system axon regeneration. Nature. PMID 27027288 DOI: 10.1038/Nature17623  0.769
2015 Zhang S, Burda JE, Anderson MA, Zhao Z, Ao Y, Cheng Y, Sun Y, Deming TJ, Sofroniew MV. Thermoresponsive Copolypeptide Hydrogel Vehicles for Central Nervous System Cell Delivery. Acs Biomaterials Science & Engineering. 1: 705-717. PMID 27547820 DOI: 10.1021/Acsbiomaterials.5B00153  0.765
2015 Levine J, Kwon E, Paez P, Yan W, Czerwieniec G, Loo JA, Sofroniew MV, Wanner IB. Traumatically injured astrocytes release a proteomic signature modulated by STAT3-dependent cell survival. Glia. PMID 26683444 DOI: 10.1002/Glia.22953  0.404
2015 Pekny M, Pekna M, Messing A, Steinhäuser C, Lee JM, Parpura V, Hol EM, Sofroniew MV, Verkhratsky A. Astrocytes: a central element in neurological diseases. Acta Neuropathologica. PMID 26671410 DOI: 10.1007/S00401-015-1513-1  0.386
2015 Duan H, Ge W, Zhang A, Xi Y, Chen Z, Luo D, Cheng Y, Fan KS, Horvath S, Sofroniew MV, Cheng L, Yang Z, Sun YE, Li X. Transcriptome analyses reveal molecular mechanisms underlying functional recovery after spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 26460053 DOI: 10.1073/pnas.1510176112  0.381
2015 Khakh BS, Sofroniew MV. Diversity of astrocyte functions and phenotypes in neural circuits. Nature Neuroscience. 18: 942-52. PMID 26108722 DOI: 10.1038/Nn.4043  0.389
2015 Sofroniew MV. Astrocyte barriers to neurotoxic inflammation. Nature Reviews. Neuroscience. 16: 249-63. PMID 25891508 DOI: 10.1038/nrn3898  0.404
2015 Burda JE, Bernstein AM, Sofroniew MV. Astrocyte roles in traumatic brain injury. Experimental Neurology. PMID 25828533 DOI: 10.1016/J.Expneurol.2015.03.020  0.779
2014 Jiang R, Haustein MD, Sofroniew MV, Khakh BS. Imaging intracellular Ca²⁺ signals in striatal astrocytes from adult mice using genetically-encoded calcium indicators. Journal of Visualized Experiments : Jove. e51972. PMID 25490346 DOI: 10.3791/51972  0.304
2014 Verkhratsky A, Parpura V, Pekna M, Pekny M, Sofroniew M. Glia in the pathogenesis of neurodegenerative diseases. Biochemical Society Transactions. 42: 1291-301. PMID 25233406 DOI: 10.1042/Bst20140107  0.382
2014 O'Callaghan JP, Kelly KA, VanGilder RL, Sofroniew MV, Miller DB. Early activation of STAT3 regulates reactive astrogliosis induced by diverse forms of neurotoxicity. Plos One. 9: e102003. PMID 25025494 DOI: 10.1371/journal.pone.0102003  0.419
2014 Kim RY, Hoffman AS, Itoh N, Ao Y, Spence R, Sofroniew MV, Voskuhl RR. Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 274: 53-61. PMID 25005117 DOI: 10.1016/J.Jneuroim.2014.06.009  0.397
2014 Khakh BS, Sofroniew MV. Astrocytes and Huntington's disease. Acs Chemical Neuroscience. 5: 494-6. PMID 24842291 DOI: 10.1021/Cn500100R  0.347
2014 Thomsen GM, Le Belle JE, Harnisch JA, Mc Donald WS, Hovda DA, Sofroniew MV, Kornblum HI, Harris NG. Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone. Stem Cell Research. 13: 48-60. PMID 24835668 DOI: 10.1016/J.Scr.2014.04.013  0.381
2014 Tong X, Ao Y, Faas GC, Nwaobi SE, Xu J, Haustein MD, Anderson MA, Mody I, Olsen ML, Sofroniew MV, Khakh BS. Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice. Nature Neuroscience. 17: 694-703. PMID 24686787 DOI: 10.1038/Nn.3691  0.333
2014 Burda JE, Sofroniew MV. Reactive gliosis and the multicellular response to CNS damage and disease. Neuron. 81: 229-48. PMID 24462092 DOI: 10.1016/J.Neuron.2013.12.034  0.775
2014 Anderson MA, Ao Y, Sofroniew MV. Heterogeneity of reactive astrocytes. Neuroscience Letters. 565: 23-9. PMID 24361547 DOI: 10.1016/j.neulet.2013.12.030  0.437
2014 Sofroniew MV. Multiple roles for astrocytes as effectors of cytokines and inflammatory mediators. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 20: 160-72. PMID 24106265 DOI: 10.1177/1073858413504466  0.377
2013 Wanner IB, Anderson MA, Song B, Levine J, Fernandez A, Gray-Thompson Z, Ao Y, Sofroniew MV. Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12870-86. PMID 23904622 DOI: 10.1523/JNEUROSCI.2121-13.2013  0.447
2013 Spence RD, Wisdom AJ, Cao Y, Hill HM, Mongerson CR, Stapornkul B, Itoh N, Sofroniew MV, Voskuhl RR. Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERα signaling on astrocytes but not through ERβ signaling on astrocytes or neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10924-33. PMID 23804112 DOI: 10.1523/Jneurosci.0886-13.2013  0.335
2013 Shigetomi E, Bushong EA, Haustein MD, Tong X, Jackson-Weaver O, Kracun S, Xu J, Sofroniew MV, Ellisman MH, Khakh BS. Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses. The Journal of General Physiology. 141: 633-47. PMID 23589582 DOI: 10.1085/Jgp.201210949  0.324
2012 Hamby ME, Coppola G, Ao Y, Geschwind DH, Khakh BS, Sofroniew MV. Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14489-510. PMID 23077035 DOI: 10.1523/Jneurosci.1256-12.2012  0.343
2012 Song B, Song J, Zhang S, Anderson MA, Ao Y, Yang CY, Deming TJ, Sofroniew MV. Sustained local delivery of bioactive nerve growth factor in the central nervous system via tunable diblock copolypeptide hydrogel depots. Biomaterials. 33: 9105-16. PMID 22985994 DOI: 10.1016/J.Biomaterials.2012.08.060  0.316
2012 Nobuta H, Ghiani CA, Paez PM, Spreuer V, Dong H, Korsak RA, Manukyan A, Li J, Vinters HV, Huang EJ, Rowitch DH, Sofroniew MV, Campagnoni AT, de Vellis J, Waschek JA. STAT3-mediated astrogliosis protects myelin development in neonatal brain injury. Annals of Neurology. 72: 750-65. PMID 22941903 DOI: 10.1002/Ana.23670  0.403
2012 Argaw AT, Asp L, Zhang J, Navrazhina K, Pham T, Mariani JN, Mahase S, Dutta DJ, Seto J, Kramer EG, Ferrara N, Sofroniew MV, John GR. Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease. The Journal of Clinical Investigation. 122: 2454-68. PMID 22653056 DOI: 10.1172/Jci60842  0.339
2012 Cushman JD, Maldonado J, Kwon EE, Garcia AD, Fan G, Imura T, Sofroniew MV, Fanselow MS. Juvenile neurogenesis makes essential contributions to adult brain structure and plays a sex-dependent role in fear memories. Frontiers in Behavioral Neuroscience. 6: 3. PMID 22347173 DOI: 10.3389/Fnbeh.2012.00003  0.562
2012 Verkhratsky A, Sofroniew MV, Messing A, deLanerolle NC, Rempe D, Rodríguez JJ, Nedergaard M. Neurological diseases as primary gliopathies: a reassessment of neurocentrism. Asn Neuro. 4. PMID 22339481 DOI: 10.1042/An20120010  0.409
2012 Sofroniew MV. Transgenic techniques for cell ablation or molecular deletion to investigate functions of astrocytes and other GFAP-expressing cell types. Methods in Molecular Biology (Clifton, N.J.). 814: 531-44. PMID 22144330 DOI: 10.1007/978-1-61779-452-0_35  0.362
2011 Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8306-19. PMID 21632951 DOI: 10.1523/Jneurosci.0567-11.2011  0.429
2011 Spence RD, Hamby ME, Umeda E, Itoh N, Du S, Wisdom AJ, Cao Y, Bondar G, Lam J, Ao Y, Sandoval F, Suriany S, Sofroniew MV, Voskuhl RR. Neuroprotection mediated through estrogen receptor-alpha in astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 108: 8867-72. PMID 21555578 DOI: 10.1073/Pnas.1103833108  0.378
2011 Wang X, Imura T, Sofroniew MV, Fushiki S. Loss of adenomatous polyposis coli in Bergmann glia disrupts their unique architecture and leads to cell nonautonomous neurodegeneration of cerebellar Purkinje neurons. Glia. 59: 857-68. PMID 21381115 DOI: 10.1002/glia.21154  0.404
2011 Sofroniew MV. Neuromyelitis optica: circulating autoantibodies provoke astrocyte-mediated neural dysfunction. Neurology. 76: 1202-3. PMID 21368284 DOI: 10.1212/WNL.0b013e3182143355  0.348
2010 Imura T, Wang X, Noda T, Sofroniew MV, Fushiki S. Adenomatous polyposis coli is essential for both neuronal differentiation and maintenance of adult neural stem cells in subventricular zone and hippocampus. Stem Cells (Dayton, Ohio). 28: 2053-64. PMID 21089118 DOI: 10.1002/stem.524  0.397
2010 Hamby ME, Sofroniew MV. Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 494-506. PMID 20880511 DOI: 10.1016/j.nurt.2010.07.003  0.383
2010 Sarafian TA, Montes C, Imura T, Qi J, Coppola G, Geschwind DH, Sofroniew MV. Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro. Plos One. 5: e9532. PMID 20224768 DOI: 10.1371/journal.pone.0009532  0.375
2010 Sofroniew MV, Vinters HV. Astrocytes: biology and pathology. Acta Neuropathologica. 119: 7-35. PMID 20012068 DOI: 10.1007/S00401-009-0619-8  0.464
2009 Sofroniew MV. Molecular dissection of reactive astrogliosis and glial scar formation. Trends in Neurosciences. 32: 638-47. PMID 19782411 DOI: 10.1016/j.tins.2009.08.002  0.349
2009 Courtine G, Gerasimenko Y, van den Brand R, Yew A, Musienko P, Zhong H, Song B, Ao Y, Ichiyama RM, Lavrov I, Roy RR, Sofroniew MV, Edgerton VR. Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature Neuroscience. 12: 1333-42. PMID 19767747 DOI: 10.1038/Nn.2401  0.311
2009 Voskuhl RR, Peterson RS, Song B, Ao Y, Morales LB, Tiwari-Woodruff S, Sofroniew MV. Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11511-22. PMID 19759299 DOI: 10.1523/Jneurosci.1514-09.2009  0.387
2009 Madison RD, Sofroniew MV, Robinson GA. Schwann cell influence on motor neuron regeneration accuracy. Neuroscience. 163: 213-21. PMID 19505536 DOI: 10.1016/j.neuroscience.2009.05.073  0.359
2009 Yang CY, Song B, Ao Y, Nowak AP, Abelowitz RB, Korsak RA, Havton LA, Deming TJ, Sofroniew MV. Biocompatibility of amphiphilic diblock copolypeptide hydrogels in the central nervous system. Biomaterials. 30: 2881-98. PMID 19251318 DOI: 10.1016/J.Biomaterials.2009.01.056  0.351
2009 Gregorian C, Nakashima J, Le Belle J, Ohab J, Kim R, Liu A, Smith KB, Groszer M, Garcia AD, Sofroniew MV, Carmichael ST, Kornblum HI, Liu X, Wu H. Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1874-86. PMID 19211894 DOI: 10.1523/Jneurosci.3095-08.2009  0.406
2008 Herrmann JE, Imura T, Song B, Qi J, Ao Y, Nguyen TK, Korsak RA, Takeda K, Akira S, Sofroniew MV. STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7231-43. PMID 18614693 DOI: 10.1523/JNEUROSCI.1709-08.2008  0.6
2008 Shigetomi E, Bowser DN, Sofroniew MV, Khakh BS. Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6659-63. PMID 18579739 DOI: 10.1523/Jneurosci.1717-08.2008  0.326
2008 Lepore AC, Dejea C, Carmen J, Rauck B, Kerr DA, Sofroniew MV, Maragakis NJ. Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration. Experimental Neurology. 211: 423-32. PMID 18410928 DOI: 10.1016/J.Expneurol.2008.02.020  0.415
2008 Otis TS, Sofroniew MV. Glia get excited. Nature Neuroscience. 11: 379-80. PMID 18368040 DOI: 10.1038/nn0408-379  0.335
2008 Courtine G, Song B, Roy RR, Zhong H, Herrmann JE, Ao Y, Qi J, Edgerton VR, Sofroniew MV. Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury. Nature Medicine. 14: 69-74. PMID 18157143 DOI: 10.1038/Nm1682  0.595
2007 Savidge TC, Sofroniew MV, Neunlist M. Starring roles for astroglia in barrier pathologies of gut and brain. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 731-6. PMID 17607301 DOI: 10.1038/labinvest.3700600  0.329
2007 Savidge TC, Newman P, Pothoulakis C, Ruhl A, Neunlist M, Bourreille A, Hurst R, Sofroniew MV. Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione. Gastroenterology. 132: 1344-58. PMID 17408650 DOI: 10.1053/j.gastro.2007.01.051  0.367
2007 Saxe MD, Malleret G, Vronskaya S, Mendez I, Garcia AD, Sofroniew MV, Kandel ER, Hen R. Paradoxical influence of hippocampal neurogenesis on working memory. Proceedings of the National Academy of Sciences of the United States of America. 104: 4642-6. PMID 17360577 DOI: 10.1073/Pnas.0611718104  0.351
2006 Saxe MD, Battaglia F, Wang JW, Malleret G, David DJ, Monckton JE, Garcia AD, Sofroniew MV, Kandel ER, Santarelli L, Hen R, Drew MR. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 103: 17501-6. PMID 17088541 DOI: 10.1073/Pnas.0607207103  0.423
2006 Myer DJ, Gurkoff GG, Lee SM, Hovda DA, Sofroniew MV. Essential protective roles of reactive astrocytes in traumatic brain injury. Brain : a Journal of Neurology. 129: 2761-72. PMID 16825202 DOI: 10.1093/Brain/Awl165  0.783
2006 Imura T, Nakano I, Kornblum HI, Sofroniew MV. Phenotypic and functional heterogeneity of GFAP-expressing cells in vitro: differential expression of LeX/CD15 by GFAP-expressing multipotent neural stem cells and non-neurogenic astrocytes. Glia. 53: 277-93. PMID 16267834 DOI: 10.1002/glia.20281  0.372
2005 Dougherty JD, Garcia AD, Nakano I, Livingstone M, Norris B, Polakiewicz R, Wexler EM, Sofroniew MV, Kornblum HI, Geschwind DH. PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10773-85. PMID 16291951 DOI: 10.1523/Jneurosci.3207-05.2005  0.437
2005 Sofroniew MV. Reactive astrocytes in neural repair and protection. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 400-7. PMID 16151042 DOI: 10.1177/1073858405278321  0.463
2005 Nakano I, Paucar AA, Bajpai R, Dougherty JD, Zewail A, Kelly TK, Kim KJ, Ou J, Groszer M, Imura T, Freije WA, Nelson SF, Sofroniew MV, Wu H, Liu X, et al. Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. The Journal of Cell Biology. 170: 413-27. PMID 16061694 DOI: 10.1083/Jcb.200412115  0.362
2004 Garcia AD, Doan NB, Imura T, Bush TG, Sofroniew MV. GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nature Neuroscience. 7: 1233-41. PMID 15494728 DOI: 10.1038/nn1340  0.448
2004 Faulkner JR, Herrmann JE, Woo MJ, Tansey KE, Doan NB, Sofroniew MV. Reactive astrocytes protect tissue and preserve function after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2143-55. PMID 14999065 DOI: 10.1523/JNEUROSCI.3547-03.2004  0.723
2003 Morshead CM, Garcia AD, Sofroniew MV, van Der Kooy D. The ablation of glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cells. The European Journal of Neuroscience. 18: 76-84. PMID 12859339 DOI: 10.1046/j.1460-9568.2003.02727.x  0.438
2003 Imura T, Kornblum HI, Sofroniew MV. The predominant neural stem cell isolated from postnatal and adult forebrain but not early embryonic forebrain expresses GFAP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2824-32. PMID 12684469 DOI: 10.1523/Jneurosci.23-07-02824.2003  0.366
2001 Sofroniew MV, Howe CL, Mobley WC. Nerve growth factor signaling, neuroprotection, and neural repair. Annual Review of Neuroscience. 24: 1217-81. PMID 11520933 DOI: 10.1146/Annurev.Neuro.24.1.1217  0.348
2001 Kelly S, Bieneman A, Horsburgh K, Hughes D, Sofroniew MV, McCulloch J, Uney JB. Targeting expression of hsp70i to discrete neuronal populations using the Lmo-1 promoter: assessment of the neuroprotective effects of hsp70i in vivo and in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 972-81. PMID 11487733 DOI: 10.1097/00004647-200108000-00010  0.391
2000 Bucher K, Sofroniew MV, Pannell R, Impey H, Smith AJ, Torres EM, Dunnett SB, Jin Y, Baer R, Rabbitts TH. The T cell oncogene Tal2 is necessary for normal development of the mouse brain. Developmental Biology. 227: 533-44. PMID 11071772 DOI: 10.1006/dbio.2000.9920  0.496
2000 Takei N, Torres E, Yuhara A, Jongsma H, Otto C, Korhonen L, Abiru Y, Skoglösa Y, Schütz G, Hatanaka H, Sofroniew MV, Lindholm D. Pituitary adenylate cyclase-activating polypeptide promotes the survival of basal forebrain cholinergic neurons in vitro and in vivo: comparison with effects of nerve growth factor. The European Journal of Neuroscience. 12: 2273-80. PMID 10947806 DOI: 10.1046/j.1460-9568.2000.00118.x  0.377
1999 Sofroniew MV, Bush TG, Blumauer N, Lawrence Kruger, Mucke L, Johnson MH. Genetically-targeted and conditionally-regulated ablation of astroglial cells in the central, enteric and peripheral nervous systems in adult transgenic mice. Brain Research. 835: 91-5. PMID 10448200 DOI: 10.1016/S0006-8993(99)01639-X  0.39
1999 Bush TG, Puvanachandra N, Horner CH, Polito A, Ostenfeld T, Svendsen CN, Mucke L, Johnson MH, Sofroniew MV. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron. 23: 297-308. PMID 10399936 DOI: 10.1016/S0896-6273(00)80781-3  0.453
1999 Panni MK, Atkinson J, Sofroniew MV. Leukaemia inhibitory factor prevents loss of p75-nerve growth factor receptor immunoreactivity in medial septal neurons following fimbria-fornix lesions. Neuroscience. 89: 1113-21. PMID 10362299 DOI: 10.1016/S0306-4522(98)00385-6  0.346
1999 French SJ, Humby T, Horner CH, Sofroniew MV, Rattray M. Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine. Brain Research. Molecular Brain Research. 67: 124-36. PMID 10101239 DOI: 10.1016/S0169-328X(99)00048-0  0.577
1999 Kimonides VG, Spillantini MG, Sofroniew MV, Fawcett JW, Herbert J. Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures. Neuroscience. 89: 429-36. PMID 10077325 DOI: 10.1016/S0306-4522(98)00347-9  0.302
1998 Panni MK, Cooper JD, Sofroniew MV. Ganglioside GM1 potentiates NGF action on axotomised medial septal cholinergic neurons. Brain Research. 812: 76-80. PMID 9813248 DOI: 10.1016/S0006-8993(98)00948-2  0.342
1998 Lam HH, Bhardwaj A, O'Connell MT, Hanley DF, Traystman RJ, Sofroniew MV. Nerve growth factor rapidly suppresses basal, NMDA-evoked, and AMPA-evoked nitric oxide synthase activity in rat hippocampus in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 10926-31. PMID 9724806 DOI: 10.1073/pnas.95.18.10926  0.343
1998 Bush TG, Savidge TC, Freeman TC, Cox HJ, Campbell EA, Mucke L, Johnson MH, Sofroniew MV. Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice. Cell. 93: 189-201. PMID 9568712 DOI: 10.1016/S0092-8674(00)81571-8  0.372
1997 Mai JK, Lensing-Höhn S, Ende AA, Sofroniew MV. Developmental organization of neurophysin neurons in the human brain. The Journal of Comparative Neurology. 385: 477-89. PMID 9300772 DOI: 10.1002/(SICI)1096-9861(19970901)385:3<477::AID-CNE10>3.0.CO;2-H  0.351
1997 Hinks GL, Shah B, French SJ, Campos LS, Staley K, Hughes J, Sofroniew MV. Expression of LIM protein genes Lmo1, Lmo2, and Lmo3 in adult mouse hippocampus and other forebrain regions: differential regulation by seizure activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5549-59. PMID 9204936 DOI: 10.1523/Jneurosci.17-14-05549.1997  0.653
1997 Kew JN, Sofroniew MV. Brain-derived neurotrophic factor, acidic and basic fibroblast growth factors, insulin-like growth factor-I, and various antioxidants do not prevent the apoptotic death of developing septal cholinergic neurons following nerve growth factor withdrawal in vitro. Neuroscience. 76: 809-20. PMID 9135053 DOI: 10.1016/S0306-4522(96)00398-3  0.344
1996 Cooper JD, Sofroniew MV. Increased vulnerability of septal cholinergic neurons to partial loss of target neurons in aged rats. Neuroscience. 75: 29-35. PMID 8923520 DOI: 10.1016/0306-4522(96)00240-0  0.374
1996 De Lacalle S, Cooper JD, Svendsen CN, Dunnett SB, Sofroniew MV. Reduced retrograde labelling with fluorescent tracer accompanies neuronal atrophy of basal forebrain cholinergic neurons in aged rats. Neuroscience. 75: 19-27. PMID 8923519 DOI: 10.1016/0306-4522(96)00239-4  0.514
1996 Kew JN, Smith DW, Sofroniew MV. Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: protection by cyclic AMP analogue and high potassium. Neuroscience. 70: 329-39. PMID 8848143 DOI: 10.1016/0306-4522(95)00365-7  0.327
1996 Page KJ, Sofroniew MV. The ascending basal forebrain cholinergic system. Progress in Brain Research. 107: 513-22. PMID 8782539 DOI: 10.1016/S0079-6123(08)61884-1  0.381
1996 Cooper JD, Skepper JN, Berzaghi MD, Lindholm D, Sofroniew MV. Delayed death of septal cholinergic neurons after excitotoxic ablation of hippocampal neurons during early postnatal development in the rat. Experimental Neurology. 139: 143-55. PMID 8635561 DOI: 10.1006/exnr.1996.0089  0.388
1995 Kennedy PG, Gairns J, Kew JN, Sofroniew MV. Attempted modulation of herpes simplex virus (HSV) infection of neurons in culture by fibroblast growth factor. Journal of Neurovirology. 1: 399-404. PMID 9222383 DOI: 10.3109/13550289509111030  0.349
1995 Kew JN, Sofroniew MV. Ciliary neurotrophic factor supports p75NGFR-immunoreactive non-cholinergic, but not cholinergic, developing septal neurons in vitro. Neuroscience. 66: 793-804. PMID 7651610 DOI: 10.1016/0306-4522(94)00590-2  0.327
1994 Svendsen CN, Kew JN, Staley K, Sofroniew MV. Death of developing septal cholinergic neurons following NGF withdrawal in vitro: protection by protein synthesis inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 75-87. PMID 8283253 DOI: 10.1523/Jneurosci.14-01-00075.1994  0.341
1994 Heisenberg CP, Cooper JD, Berke J, Sofroniew MV. NMDA potentiates NGF-induced sprouting of septal cholinergic fibres. Neuroreport. 5: 413-6. PMID 8003664 DOI: 10.1097/00001756-199401120-00010  0.307
1994 Van Der Lugt NMT, Domen J, Linders K, Van Roon M, Robanus-Maandag E, Te Riele H, Van Der Valk M, Deschamps J, Sofroniew M, Van Lohuizen M, Berns A. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene Genes and Development. 8: 757-769. PMID 7926765 DOI: 10.1101/Gad.8.7.757  0.311
1994 Panni MK, Wilson VJ, Capoor U, Sofroniew MV, Rattray M. Changes in CCK mRNA in hippocampal neurones following fimbria fornix transection. Neuroreport. 5: 1377-80. PMID 7919204 DOI: 10.1097/00001756-199406000-00022  0.355
1994 Wilson VJ, Oddiah D, Sofroniew MV, Panni MK, Rattray M. Down-regulation of protein kinase C isoform gene expression in degenerating thalamic neurones--lack of induction in reactive glial cells. Biochemical Society Transactions. 22: 291S. PMID 7821550 DOI: 10.1042/Bst022291S  0.401
1994 Cooper JD, Lindholm D, Sofroniew MV. Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged rats. Neuroscience. 62: 625-9. PMID 7532836 DOI: 10.1016/0306-4522(94)90462-6  0.342
1993 Sofroniew MV, Cooper JD, Svendsen CN, Crossman P, Ip NY, Lindsay RM, Zafra F, Lindholm D. Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5263-76. PMID 8254373 DOI: 10.1523/Jneurosci.13-12-05263.1993  0.376
1993 Uney JB, Kew JN, Staley K, Tyers P, Sofroniew MV. Transfection-mediated expression of human Hsp70i protects rat dorsal root ganglian neurones and glia from severe heat stress. Febs Letters. 334: 313-6. PMID 8243639 DOI: 10.1016/0014-5793(93)80701-U  0.334
1993 Sofroniew MV, Mobley WC. On the possibility of positive-feedback in trophic interactions between afferent and target neurons Seminars in Neuroscience. 5: 309-312. DOI: 10.1016/S1044-5765(05)80036-3  0.371
1993 Sofroniew MV, Cooper JD. Neurotrophic mechanisms and neuronal degeneration Seminars in Neuroscience. 5: 285-294. DOI: 10.1016/S1044-5765(05)80034-X  0.375
1992 Isacson O, Sofroniew MV. Neuronal loss or replacement in the injured adult cerebral neocortex induces extensive remodeling of intrinsic and afferent neural systems. Experimental Neurology. 117: 151-75. PMID 1379936 DOI: 10.1016/0014-4886(92)90123-8  0.39
1991 Mai JK, Kedziora O, Teckhaus L, Sofroniew MV. Evidence for subdivisions in the human suprachiasmatic nucleus. The Journal of Comparative Neurology. 305: 508-25. PMID 2037718 DOI: 10.1002/cne.903050312  0.348
1991 Sofroniew MV. Can activity modulate the susceptibility of neurons to degeneration? Neurobiology of Aging. 12: 351-2; discussion 35. PMID 1961371 DOI: 10.1016/0197-4580(91)90020-K  0.338
1991 Svendsen CN, Cooper JD, Sofroniew MV. Trophic factor effects on septal cholinergic neurons. Annals of the New York Academy of Sciences. 640: 91-4. PMID 1776766 DOI: 10.1111/J.1749-6632.1991.Tb00197.X  0.396
1990 Wood SJ, Pritchard J, Sofroniew MV. Re-expression of Nerve Growth Factor Receptor after Axonal Injury Recapitulates a Developmental Event in Motor Neurons: Differential Regulation when Regeneration is Allowed or Prevented. The European Journal of Neuroscience. 2: 650-7. PMID 12106299 DOI: 10.1111/j.1460-9568.1990.tb00454.x  0.389
1990 O'Brien TS, Svendsen CN, Isacson O, Sofroniew MV. Loss of true blue labelling from the medial septum following transection of the fimbria-fornix: evidence for the death of cholinergic and non-cholinergic neurons. Brain Research. 508: 249-56. PMID 2306616 DOI: 10.1016/0006-8993(90)90403-X  0.381
1990 Sofroniew MV, Dunnett SB, Isacson O. Remodelling of intrinsic and afferent systems in neocortex with cortical transplants. Progress in Brain Research. 82: 313-20. PMID 2290944 DOI: 10.1016/S0079-6123(08)62618-7  0.518
1990 Isacson O, Hantraye P, Maziere M, Sofroniew MV, Riche D. Apomorphine-induced dyskinesias after excitotoxic caudate-putamen lesions and the effects of neural transplantation in non-human primates. Progress in Brain Research. 82: 523-33. PMID 2149770 DOI: 10.1016/S0079-6123(08)62643-6  0.307
1990 Sofroniew MV, Galletly NP, Isacson O, Svendsen CN. Survival of adult basal forebrain cholinergic neurons after loss of target neurons. Science (New York, N.Y.). 247: 338-42. PMID 1688664 DOI: 10.1126/Science.1688664  0.373
1989 Broadwell RD, Charlton HM, Ganong WF, Salcman M, Sofroniew M. Allografts of CNS tissue possess a blood-brain barrier. I. Grafts of medial preoptic area in hypogonadal mice. Experimental Neurology. 105: 135-51. PMID 2753114 DOI: 10.1016/0014-4886(89)90113-1  0.469
1989 Garten LL, Sofroniew MV, Dyball RE. A direct catecholaminergic projection from the brainstem to the neurohypophysis of the rat. Neuroscience. 33: 149-55. PMID 2601853 DOI: 10.1016/0306-4522(89)90317-5  0.345
1989 Isacson O, Riche D, Hantraye P, Sofroniew MV, Maziere M. A primate model of Huntington's disease: cross-species implantation of striatal precursor cells to the excitotoxically lesioned baboon caudate-putamen. Experimental Brain Research. 75: 213-20. PMID 2523313 DOI: 10.1007/BF00248544  0.362
1988 Lams BE, Isacson O, Sofroniew MV. Loss of transmitter-associated enzyme staining following axotomy does not indicate death of brainstem cholinergic neurons. Brain Research. 475: 401-6. PMID 3214743 DOI: 10.1016/0006-8993(88)90635-X  0.354
1988 Isacson O, Wictorin K, Fischer W, Sofroniew MV, Björklund A. Fetal cortical cell suspension grafts to the excitotoxically lesioned neocortex: anatomical and neurochemical studies of trophic interactions. Progress in Brain Research. 78: 13-26. PMID 3073408 DOI: 10.1016/S0079-6123(08)60261-7  0.348
1987 Pearson RC, Sofroniew MV, Powell TP. The cholinergic nuclei of the basal forebrain of the rat: hypertrophy following contralateral cortical damage or section of the corpus callosum. Brain Research. 411: 332-40. PMID 3607437 DOI: 10.1016/0006-8993(87)91085-7  0.516
1987 Sofroniew MV, Pearson RC, Powell TP. The cholinergic nuclei of the basal forebrain of the rat: normal structure, development and experimentally induced degeneration. Brain Research. 411: 310-31. PMID 3607436 DOI: 10.1016/0006-8993(87)91084-5  0.541
1987 Kowall NW, Ferrante RJ, Beal MF, Richardson EP, Sofroniew MV, Cuello AC, Martin JB. Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: a combined immunocytochemical and enzyme histochemical study. Neuroscience. 20: 817-28. PMID 2885780 DOI: 10.1016/0306-4522(87)90242-9  0.459
1986 Sofroniew MV, Pearson RC, Cuello AC, Tagari PC, Stephens PH. Parenterally administered GM1 ganglioside prevents retrograde degeneration of cholinergic cells of the rat basal forebrain. Brain Research. 398: 393-6. PMID 3801911 DOI: 10.1016/0006-8993(86)91503-9  0.477
1986 Cuello AC, Stephens PH, Tagari PC, Sofroniew MV, Pearson RC. Retrograde changes in the nucleus basalis of the rat, caused by cortical damage, are prevented by exogenous ganglioside GM1. Brain Research. 376: 373-7. PMID 3730841 DOI: 10.1016/0006-8993(86)90202-7  0.434
1986 Connaughton M, Priestley JV, Sofroniew MV, Eckenstein F, Cuello AC. Inputs to motoneurones in the hypoglossal nucleus of the rat: light and electron microscopic immunocytochemistry for choline acetyltransferase, substance P and enkephalins using monoclonal antibodies. Neuroscience. 17: 205-24. PMID 2421199 DOI: 10.1016/0306-4522(86)90237-X  0.418
1985 Stephens PH, Cuello AC, Sofroniew MV, Pearson RC, Tagari P. Effect of unilateral decortication on choline acetyltransferase activity in the nucleus basalis and other areas of the rat brain. Journal of Neurochemistry. 45: 1021-6. PMID 4031875 DOI: 10.1111/j.1471-4159.1985.tb05517.x  0.443
1985 Pearson RC, Sofroniew MV, Powell TP. Hypertrophy of cholinergic neurones of the rat basal nucleus following section of the corpus callosum. Brain Research. 338: 337-40. PMID 4027599 DOI: 10.1016/0006-8993(85)90164-7  0.523
1985 Sofroniew MV, Priestley JV, Consolazione A, Eckenstein F, Cuello AC. Cholinergic projections from the midbrain and pons to the thalamus in the rat, identified by combined retrograde tracing and choline acetyltransferase immunohistochemistry. Brain Research. 329: 213-23. PMID 3978443 DOI: 10.1016/0006-8993(85)90527-X  0.448
1984 Pearson RC, Sofroniew MV, Powell TP. Hypertrophy of immunohistochemically identified cholinergic neurons of the basal nucleus of Meynert following ablation of the contralateral cortex in the rat. Brain Research. 311: 194-8. PMID 6488042 DOI: 10.1016/0006-8993(84)91418-5  0.53
1984 MacMillan FM, Sofroniew MV, Sidebottom E, Cuello AC. Immunocytochemistry with monoclonal anti-immunoglobulin as a developing reagent: application to immunoperoxidase staining and radioimmunocytochemistry. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 32: 76-82. PMID 6418791  0.358
1983 Sofroniew MV, Pearson RC, Eckenstein F, Cuello AC, Powell TP. Retrograde changes in cholinergic neurons in the basal forebrain of the rat following cortical damage. Brain Research. 289: 370-4. PMID 6661653 DOI: 10.1016/0006-8993(83)90045-8  0.631
1983 Pearson RC, Sofroniew MV, Cuello AC, Powell TP, Eckenstein F, Esiri MM, Wilcock GK. Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase. Brain Research. 289: 375-9. PMID 6362777 DOI: 10.1016/0006-8993(83)90046-X  0.639
1983 Sofroniew MV, MacMillan FM, Eckenstein F, Schrell U, Joh T, Gähwiler BH, Dreifuss JJ, Cuello AC. Immunohistochemical approaches to the study of neuroendocrine and related neurones. Quarterly Journal of Experimental Physiology (Cambridge, England). 68: 435-47. PMID 6193552  0.445
1983 Cuello AC, Priestley JV, Sofroniew MV. Immunocytochemistry and neurobiology. Quarterly Journal of Experimental Physiology (Cambridge, England). 68: 545-78. PMID 6139841 DOI: 10.1113/Expphysiol.1983.Sp002748  0.404
1982 Sofroniew MV, Eckenstein F, Thoenen H, Cuello AC. Topography of choline acetyltransferase-containing neurons in the forebrain of the rat. Neuroscience Letters. 33: 7-12. PMID 6759989 DOI: 10.1016/0304-3940(82)90121-5  0.451
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