Cornelius Kros - Publications

Affiliations: 
Sussex University, Falmer, England, United Kingdom 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kenyon EJ, Kirkwood NK, Kitcher SR, Goodyear RJ, Derudas M, Cantillon DM, Baxendale S, de la Vega de León A, Mahieu VN, Osgood RT, Donald Wilson C, Bull JC, Waddell SJ, Whitfield TT, Ward SE, ... Kros CJ, et al. Identification of a novel series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity. Jci Insight. PMID 33735112 DOI: 10.1172/jci.insight.145704  0.443
2019 Jeng JY, Ceriani F, Hendry A, Johnson SL, Yen P, Simmons DD, Kros CJ, Marcotti W. Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea. The Journal of Physiology. PMID 31661723 DOI: 10.1113/JP279012  0.424
2019 Kitcher SR, Kirkwood NK, Camci ED, Wu P, Gibson RM, Redila VA, Simon JA, Rubel EW, Raible DW, Richardson GP, Kros CJ. ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity. Jci Insight. 4. PMID 31391343 DOI: 10.1172/Jci.Insight.126764  0.494
2019 O'Reilly M, Kirkwood NK, Kenyon EJ, Huckvale R, Cantillon DM, Waddell SJ, Ward SE, Richardson GP, Kros CJ, Derudas M. Design, synthesis and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the mechano-electrical transducer channel. Journal of Medicinal Chemistry. PMID 31083995 DOI: 10.1021/acs.jmedchem.8b01325  0.317
2019 Ceriani F, Hendry A, Jeng JY, Johnson SL, Stephani F, Olt J, Holley MC, Mammano F, Engel J, Kros CJ, Simmons DD, Marcotti W. Coordinated calcium signalling in cochlear sensory and non-sensory cells refines afferent innervation of outer hair cells. The Embo Journal. PMID 30804003 DOI: 10.15252/Embj.201899839  0.377
2018 Corns LF, Johnson SL, Roberts T, Ranatunga KM, Hendry A, Ceriani F, Safieddine S, Steel KP, Forge A, Petit C, Furness DN, Kros CJ, Marcotti W. Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation. Nature Communications. 9: 4015. PMID 30275467 DOI: 10.1038/S41467-018-06307-W  0.528
2018 Jeong M, O'Reilly M, Kirkwood NK, Al-Aama J, Lako M, Kros CJ, Armstrong L. Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells. Cell Death & Disease. 9: 922. PMID 30206231 DOI: 10.1038/s41419-018-0967-1  0.538
2017 Kenyon EJ, Kirkwood NK, Kitcher SR, O'Reilly M, Derudas M, Cantillon DM, Goodyear RJ, Secker A, Baxendale S, Bull JC, Waddell SJ, Whitfield TT, Ward SE, Kros CJ, Richardson GP. Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death. Jci Insight. 2. PMID 29263311 DOI: 10.1172/jci.insight.96773  0.366
2017 Corns LF, Jeng JY, Richardson GP, Kros CJ, Marcotti W. TMC2 Modifies Permeation Properties of the Mechanoelectrical Transducer Channel in Early Postnatal Mouse Cochlear Outer Hair Cells. Frontiers in Molecular Neuroscience. 10: 326. PMID 29093662 DOI: 10.3389/fnmol.2017.00326  0.329
2017 Kirkwood NK, O'Reilly M, Derudas M, Kenyon EJ, Huckvale R, van Netten SM, Ward SE, Richardson GP, Kros CJ. d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity. Frontiers in Cellular Neuroscience. 11: 262. PMID 28928635 DOI: 10.3389/fncel.2017.00262  0.508
2016 Marcotti W, Corns LF, Goodyear RJ, Rzadzinska AK, Avraham KB, Steel KP, Richardson GP, Kros CJ. The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI. The Journal of Physiology. PMID 27111754 DOI: 10.1113/Jp272220  0.447
2015 Sexton JE, Desmonds T, Quick K, Taylor R, Abramowitz J, Forge A, Kros CJ, Birnbaumer L, Wood JN. The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing. Neuroscience Letters. 610: 36-42. PMID 26520460 DOI: 10.1016/j.neulet.2015.10.052  0.396
2014 Corns LF, Johnson SL, Kros CJ, Marcotti W. Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 14918-23. PMID 25228765 DOI: 10.1073/pnas.1409920111  0.409
2014 Marcotti W, Corns LF, Desmonds T, Kirkwood NK, Richardson GP, Kros CJ. Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5505-14. PMID 24741041 DOI: 10.1523/JNEUROSCI.4086-13.2014  0.437
2012 Quick K, Zhao J, Eijkelkamp N, Linley JE, Rugiero F, Cox JJ, Raouf R, Gringhuis M, Sexton JE, Abramowitz J, Taylor R, Forge A, Ashmore J, Kirkwood N, Kros CJ, et al. TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Open Biology. 2: 120068. PMID 22724068 DOI: 10.1098/rsob.120068  0.447
2011 Johnson SL, Eckrich T, Kuhn S, Zampini V, Franz C, Ranatunga KM, Roberts TP, Masetto S, Knipper M, Kros CJ, Marcotti W. Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells. Nature Neuroscience. 14: 711-7. PMID 21572434 DOI: 10.1038/nn.2803  0.453
2011 Alagramam KN, Goodyear RJ, Geng R, Furness DN, van Aken AF, Marcotti W, Kros CJ, Richardson GP. Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells. Plos One. 6: e19183. PMID 21532990 DOI: 10.1371/Journal.Pone.0019183  0.393
2009 Michalski N, Michel V, Caberlotto E, Lefèvre GM, van Aken AF, Tinevez JY, Bizard E, Houbron C, Weil D, Hardelin JP, Richardson GP, Kros CJ, Martin P, Petit C. Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells. PflüGers Archiv : European Journal of Physiology. 459: 115-30. PMID 19756723 DOI: 10.1007/S00424-009-0711-X  0.467
2009 van Netten SM, Meulenberg CJ, Lennan GW, Kros CJ. Pairwise coupling of hair cell transducer channels links auditory sensitivity and dynamic range. PflüGers Archiv : European Journal of Physiology. 458: 273-81. PMID 19048284 DOI: 10.1007/s00424-008-0617-z  0.506
2008 Goodyear RJ, Gale JE, Ranatunga KM, Kros CJ, Richardson GP. Aminoglycoside-induced phosphatidylserine externalization in sensory hair cells is regionally restricted, rapid, and reversible. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9939-52. PMID 18829952 DOI: 10.1523/JNEUROSCI.1124-08.2008  0.408
2008 van Aken AF, Atiba-Davies M, Marcotti W, Goodyear RJ, Bryant JE, Richardson GP, Noben-Trauth K, Kros CJ. TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice. The Journal of Physiology. 586: 5403-18. PMID 18801844 DOI: 10.1113/jphysiol.2008.156992  0.466
2007 Grimm C, Cuajungco MP, van Aken AF, Schnee M, Jörs S, Kros CJ, Ricci AJ, Heller S. A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse. Proceedings of the National Academy of Sciences of the United States of America. 104: 19583-8. PMID 18048323 DOI: 10.1073/Pnas.0709846104  0.357
2007 Helyer R, Cacciabue-Rivolta D, Davies D, Rivolta MN, Kros CJ, Holley MC. A model for mammalian cochlear hair cell differentiation in vitro: Effects of retinoic acid on cytoskeletal proteins and potassium conductances European Journal of Neuroscience. 25: 957-973. PMID 17331193 DOI: 10.1111/J.1460-9568.2007.05338.X  0.505
2007 Kros CJ. How to build an inner hair cell: challenges for regeneration. Hearing Research. 227: 3-10. PMID 17258412 DOI: 10.1016/j.heares.2006.12.005  0.509
2006 Evans MG, Kros CJ. The cochlea--new insights into the conversion of sound into electrical signals. The Journal of Physiology. 576: 3-5. PMID 16916902 DOI: 10.1113/jphysiol.2006.118927  0.412
2006 Kros CJ, Evans MG. Tuning in to cochlear hair cells. The Journal of Physiology. 576: 7-9. PMID 16916901 DOI: 10.1113/jphysiol.2006.118935  0.32
2006 Marcotti W, Erven A, Johnson SL, Steel KP, Kros CJ. Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea. The Journal of Physiology. 574: 677-98. PMID 16627570 DOI: 10.1113/jphysiol.2005.095661  0.508
2005 Marcotti W, van Netten SM, Kros CJ. The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels. The Journal of Physiology. 567: 505-21. PMID 15994187 DOI: 10.1113/jphysiol.2005.085951  0.411
2005 Michel V, Goodyear RJ, Weil D, Marcotti W, Perfettini I, Wolfrum U, Kros CJ, Richardson GP, Petit C. Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells. Developmental Biology. 280: 281-94. PMID 15882573 DOI: 10.1016/J.Ydbio.2005.01.014  0.416
2005 Goodyear RJ, Marcotti W, Kros CJ, Richardson GP. Development and properties of stereociliary link types in hair cells of the mouse cochlea. The Journal of Comparative Neurology. 485: 75-85. PMID 15776440 DOI: 10.1002/cne.20513  0.344
2005 Kros C. Hearing: aid from hair force. Nature. 433: 810-1. PMID 15729322 DOI: 10.1038/433810A  0.32
2005 Helyer RJ, Kennedy HJ, Davies D, Holley MC, Kros CJ. Development of outward potassium currents in inner and outer hair cells from the embryonic mouse cochlea. Audiology & Neuro-Otology. 10: 22-34. PMID 15486441 DOI: 10.1159/000081545  0.438
2004 Marcotti W, Johnson SL, Kros CJ. A transiently expressed SK current sustains and modulates action potential activity in immature mouse inner hair cells. The Journal of Physiology. 560: 691-708. PMID 15331671 DOI: 10.1113/jphysiol.2004.072868  0.358
2004 Spreadbury IC, Kros CJ, Meech RW. Effects of trypsin on large-conductance Ca(2+)-activated K(+) channels of guinea-pig outer hair cells. Hearing Research. 190: 115-27. PMID 15051134 DOI: 10.1016/S0378-5955(03)00376-9  0.332
2003 van Netten SM, Dinklo T, Marcotti W, Kros CJ. Channel gating forces govern accuracy of mechano-electrical transduction in hair cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 15510-5. PMID 14668434 DOI: 10.1073/pnas.2632626100  0.42
2003 Goodyear RJ, Legan PK, Wright MB, Marcotti W, Oganesian A, Coats SA, Booth CJ, Kros CJ, Seifert RA, Bowen-Pope DF, Richardson GP. A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9208-19. PMID 14534255  0.404
2003 Marcotti W, Johnson SL, Rusch A, Kros CJ. Sodium and calcium currents shape action potentials in immature mouse inner hair cells. The Journal of Physiology. 552: 743-61. PMID 12937295 DOI: 10.1113/jphysiol.2003.043612  0.386
2003 Marcotti W, Johnson SL, Holley MC, Kros CJ. Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells. The Journal of Physiology. 548: 383-400. PMID 12588897 DOI: 10.1113/jphysiol.2002.034801  0.474
2002 Hackett L, Davies D, Helyer R, Kennedy H, Kros C, Lawlor P, Rivolta MN, Holley M. E-cadherin and the differentiation of mammalian vestibular hair cells. Experimental Cell Research. 278: 19-30. PMID 12126954 DOI: 10.1006/Excr.2002.5574  0.384
2002 Kros CJ, Marcotti W, van Netten SM, Self TJ, Libby RT, Brown SD, Richardson GP, Steel KP. Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations. Nature Neuroscience. 5: 41-7. PMID 11753415 DOI: 10.1038/Nn784  0.381
2002 Kros C. Good vibrations: Music and the single hair cell The Biochemist. 24: 12-14. DOI: 10.1042/bio02406012  0.394
2001 Gale JE, Marcotti W, Kennedy HJ, Kros CJ, Richardson GP. FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7013-25. PMID 11549711  0.337
2001 Evans MG, Kros CJ. Hey presto! Electrophysiological characterisation of prestin, a motor protein from outer hair cells, transfected into kidney cells. The Journal of Physiology. 531: 582. PMID 11251040 DOI: 10.1111/j.1469-7793.2001.0582h.x  0.453
2001 Steel KP, Kros CJ. A genetic approach to understanding auditory function. Nature Genetics. 27: 143-9. PMID 11175778 DOI: 10.1038/84758  0.313
2000 van Netten SM, Kros CJ. Gating energies and forces of the mammalian hair cell transducer channel and related hair bundle mechanics. Proceedings. Biological Sciences / the Royal Society. 267: 1915-23. PMID 11052545 DOI: 10.1098/Rspb.2000.1230  0.329
1999 Richardson GP, Forge A, Kros CJ, Marcotti W, Becker D, Williams DS, Thorpe J, Fleming J, Brown SD, Steel KP. A missense mutation in myosin VIIA prevents aminoglycoside accumulation in early postnatal cochlear hair cells. Annals of the New York Academy of Sciences. 884: 110-24. PMID 10842588  0.468
1999 Marcotti W, Géléoc GS, Lennan GW, Kros CJ. Transient expression of an inwardly rectifying potassium conductance in developing inner and outer hair cells along the mouse cochlea. Pflugers Archiv : European Journal of Physiology. 439: 113-22. PMID 10651007 DOI: 10.1007/s004249900157  0.556
1999 Marcotti W, Kros CJ. Developmental expression of the potassium current IK,n contributes to maturation of mouse outer hair cells. The Journal of Physiology. 520: 653-60. PMID 10545133 DOI: 10.1111/j.1469-7793.1999.00653.x  0.389
1999 Lawlor P, Marcotti W, Rivolta MN, Kros CJ, Holley MC. Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9445-58. PMID 10531448  0.503
1998 Kros CJ, Ruppersberg JP, Rüsch A. Expression of a potassium current in inner hair cells during development of hearing in mice. Nature. 394: 281-4. PMID 9685158 DOI: 10.1038/28401  0.543
1998 Kros CJ. The paradox of hair cell adaptation. The Journal of Physiology. 506: 1. PMID 9481668 DOI: 10.1111/j.1469-7793.1998.001bx.x  0.437
1997 Richardson GP, Forge A, Kros CJ, Fleming J, Brown SD, Steel KP. Myosin VIIA is required for aminoglycoside accumulation in cochlear hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9506-19. PMID 9391006  0.479
1997 Géléoc GS, Lennan GW, Richardson GP, Kros CJ. A quantitative comparison of mechanoelectrical transduction in vestibular and auditory hair cells of neonatal mice. Proceedings. Biological Sciences / the Royal Society. 264: 611-21. PMID 9149428 DOI: 10.1098/rspb.1997.0087  0.447
1995 Mammano F, Kros CJ, Ashmore JF. Patch clamped responses from outer hair cells in the intact adult organ of Corti. Pflã¼Gers Archiv : European Journal of Physiology. 430: 745-50. PMID 7478927 DOI: 10.1007/Bf00386170  0.451
1994 Griguer C, Kros CJ, Sans A, Lehouelleur J. Potassium currents in type II vestibular hair cells isolated from the guinea-pig's crista ampullaris. Pflugers Archiv : European Journal of Physiology. 425: 344-52. PMID 8060388 DOI: 10.1007/Bf00374185  0.415
1994 Rüsch A, Kros CJ, Richardson GP. Block by amiloride and its derivatives of mechano-electrical transduction in outer hair cells of mouse cochlear cultures. The Journal of Physiology. 474: 75-86. PMID 7516972 DOI: 10.1113/jphysiol.1994.sp020004  0.329
1992 Kros CJ, Rüsch A, Richardson GP. Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea. Proceedings. Biological Sciences / the Royal Society. 249: 185-93. PMID 1280836 DOI: 10.1098/rspb.1992.0102  0.53
1990 Kros CJ, Crawford AC. Potassium currents in inner hair cells isolated from the guinea-pig cochlea Journal of Physiology. 421: 263-291. PMID 2348394  0.458
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