Year |
Citation |
Score |
2022 |
Fontana P, Dong Y, Pi X, Tong AB, Hecksel CW, Wang L, Fu TM, Bustamante C, Wu H. Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. Science (New York, N.Y.). 376: eabm9326. PMID 35679401 DOI: 10.1126/science.abm9326 |
0.664 |
|
2022 |
Zheng W, Shen C, Wang L, Rawson S, Xie WJ, Nist-Lund C, Wu J, Shen Z, Xia S, Holt JR, Wu H, Fu TM. pH regulates potassium conductance and drives a constitutive proton current in human TMEM175. Science Advances. 8: eabm1568. PMID 35333573 DOI: 10.1126/sciadv.abm1568 |
0.643 |
|
2022 |
Vora SM, Fontana P, Mao T, Leger V, Zhang Y, Fu TM, Lieberman J, Gehrke L, Shi M, Wang L, Iwasaki A, Wu H. Targeting stem-loop 1 of the SARS-CoV-2 5' UTR to suppress viral translation and Nsp1 evasion. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35149555 DOI: 10.1073/pnas.2117198119 |
0.66 |
|
2021 |
Shen C, Li R, Negro R, Cheng J, Vora SM, Fu TM, Wang A, He K, Andreeva L, Gao P, Tian Z, Flavell RA, Zhu S, Wu H. Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome. Cell. PMID 34678144 DOI: 10.1016/j.cell.2021.09.032 |
0.665 |
|
2021 |
Wu H, Wang Y, Ying M, Jin C, Li J, Hu X. Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli. Signal Transduction and Targeted Therapy. 6: 242. PMID 34176927 DOI: 10.1038/s41392-021-00595-3 |
0.303 |
|
2021 |
Zhu L, Xie H, Liu Q, Ma F, Wu H. Klotho inhibits H O -induced oxidative stress and apoptosis in periodontal ligament stem cells by regulating UCP2 expression. Clinical and Experimental Pharmacology & Physiology. PMID 34174105 DOI: 10.1111/1440-1681.13547 |
0.311 |
|
2021 |
Yang ZJ, Wang Q, Wu H, Hu J, Fu H, Qu Y, Yang Y, Cai Q, Efimov A, Wu M, Yen T, Wang Y. Nestin is required for spindle assembly and cell cycle progression in glioblastoma cells. Molecular Cancer Research : McR. PMID 34158391 DOI: 10.1158/1541-7786.MCR-20-0994 |
0.311 |
|
2021 |
Yuan L, Wu H, Wang B, Jia C, Liang D, Caiyin QG, Qiao J. ComX improves acid tolerance by regulating the expression of late competence proteins in Lactococcus lactis F44. Journal of Dairy Science. PMID 34147226 DOI: 10.3168/jds.2021-20184 |
0.301 |
|
2021 |
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Gasdermin D pore structure reveals preferential release of mature interleukin-1. Nature. PMID 33883744 DOI: 10.1038/s41586-021-03478-3 |
0.646 |
|
2021 |
Wang L, Chen Z, Wu H, Fu TM. Purification and cryoelectron microscopy structure determination of human V-ATPase. Star Protocols. 2: 100350. PMID 33665630 DOI: 10.1016/j.xpro.2021.100350 |
0.651 |
|
2021 |
Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H. Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nature Communications. 12: 189. PMID 33420033 DOI: 10.1038/s41467-020-20320-y |
0.666 |
|
2020 |
Wang L, Wu D, Robinson CV, Wu H, Fu TM. Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. Molecular Cell. PMID 33065002 DOI: 10.1016/j.molcel.2020.09.029 |
0.656 |
|
2020 |
Shi M, Wang L, Fontana P, Vora S, Zhang Y, Fu TM, Lieberman J, Wu H. SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv : the Preprint Server For Biology. PMID 32995777 DOI: 10.1101/2020.09.18.302901 |
0.655 |
|
2019 |
Xia S, Wang L, Fu TM, Wu H. Mechanism of TRPM2 channel gating revealed by cryo-EM. The Febs Journal. PMID 31144442 DOI: 10.1111/febs.14939 |
0.66 |
|
2019 |
Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, ... ... Wu H, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science (New York, N.Y.). 364. PMID 31097636 DOI: 10.1126/Science.Aau0159 |
0.659 |
|
2019 |
Pan L, Fu TM, Zhao W, Zhao L, Chen W, Qiu C, Liu W, Liu Z, Piai A, Fu Q, Chen S, Wu H, Chou JJ. Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling. Cell. PMID 30827683 DOI: 10.1016/j.cell.2019.02.001 |
0.659 |
|
2019 |
Shen C, Lu A, Xie WJ, Ruan J, Negro R, Egelman EH, Fu TM, Wu H. Molecular mechanism for NLRP6 inflammasome assembly and activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674671 DOI: 10.2210/Pdb6Ndj/Pdb |
0.673 |
|
2018 |
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science (New York, N.Y.). PMID 30467180 DOI: 10.1126/Science.Aav4809 |
0.653 |
|
2018 |
Luong PH, Hedl M, Yan J, Zuo T, Fu TM, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. Elife. 7. PMID 30355448 DOI: 10.7554/Elife.38539 |
0.665 |
|
2018 |
Li Y, Fu TM, Lu A, Witt K, Ruan J, Shen C, Wu H. Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proceedings of the National Academy of Sciences of the United States of America. PMID 30279182 DOI: 10.1073/pnas.1810524115 |
0.674 |
|
2018 |
Xia S, Fu TM, Wu H. Inflammation NODs to Antagonists of RIP2-XIAP Interaction. Molecular Cell. 69: 535-536. PMID 29452633 DOI: 10.1016/j.molcel.2018.02.003 |
0.659 |
|
2018 |
Fu TM, Shen C, Li Q, Zhang P, Wu H. Mechanism of ubiquitin transfer promoted by TRAF6. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432170 DOI: 10.1073/pnas.1721788115 |
0.663 |
|
2016 |
Fu TM, Li Y, Lu A, Li Z, Vajjhala PR, Cruz AC, Srivastava DB, DiMaio F, Penczek PA, Siegel RM, Stacey KJ, Egelman EH, Wu H. Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex. Molecular Cell. PMID 27746017 DOI: 10.1016/J.Molcel.2016.09.009 |
0.67 |
|
2016 |
Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu TM, Tong AB, Ploegh HL, Mao Y, Wu H. Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. Nature Structural & Molecular Biology. PMID 27043298 DOI: 10.1038/Nsmb.3199 |
0.67 |
|
2016 |
Fu Q, Fu TM, Cruz AC, Sengupta P, Thomas SK, Wang S, Siegel RM, Wu H, Chou JJ. Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor. Molecular Cell. PMID 26853147 DOI: 10.1016/J.Molcel.2016.01.009 |
0.669 |
|
2015 |
Ru H, Chambers MG, Fu TM, Tong AB, Liao M, Wu H. Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures. Cell. PMID 26548953 DOI: 10.1016/J.Cell.2015.10.055 |
0.657 |
|
2015 |
Yin Q, Fu TM, Li J, Wu H. Structural biology of innate immunity. Annual Review of Immunology. 33: 393-416. PMID 25622194 DOI: 10.1146/Annurev-Immunol-032414-112258 |
0.669 |
|
2014 |
Lu A, Kabaleeswaran V, Fu T, Magupalli VG, Wu H. Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of its Self-association to DED/DED Interactions Journal of Molecular Biology. 426: 1420-1427. PMID 24406744 DOI: 10.1016/J.Jmb.2013.12.029 |
0.669 |
|
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