Yi Zhang - Publications

Genetics/PCMM Harvard Medical School - Boston Children's Hospital 

213 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bhattacherjee A, Zhang C, Watson BR, Djekidel MN, Moffitt JR, Zhang Y. Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain. Nature Neuroscience. PMID 37845544 DOI: 10.1038/s41593-023-01455-9  0.73
2022 Wang M, Chen Z, Zhang Y. CBP/p300 and HDAC activities regulate H3K27 acetylation dynamics and zygotic genome activation in mouse preimplantation embryos. The Embo Journal. e112012. PMID 36215692 DOI: 10.15252/embj.2022112012  0.383
2022 Chen R, Liu Y, Djekidel MN, Chen W, Bhattacherjee A, Chen Z, Scolnick E, Zhang Y. Cell type-specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis. Science Advances. 8: eabm1077. PMID 35245111 DOI: 10.1126/sciadv.abm1077  0.748
2022 Zhang C, Wang M, Li Y, Zhang Y. Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition. Science Advances. 8: eabj3967. PMID 35108058 DOI: 10.1126/sciadv.abj3967  0.322
2021 Wang Y, Wang M, Djekidel MN, Chen H, Liu D, Alt FW, Zhang Y. eccDNAs are apoptotic products with high innate immunostimulatory activity. Nature. 599: 308-314. PMID 34671165 DOI: 10.1038/s41586-021-04009-w  0.72
2021 Chen R, Blosser TR, Djekidel MN, Hao J, Bhattacherjee A, Chen W, Tuesta LM, Zhuang X, Zhang Y. Decoding molecular and cellular heterogeneity of mouse nucleus accumbens. Nature Neuroscience. 24: 1757-1771. PMID 34663959 DOI: 10.1038/s41593-021-00938-x  0.761
2021 Chen Z, Djekidel MN, Zhang Y. Author Correction: Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos. Nature Genetics. PMID 33888911 DOI: 10.1038/s41588-021-00871-6  0.706
2021 Chen Z, Djekidel MN, Zhang Y. Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos. Nature Genetics. PMID 33821005 DOI: 10.1038/s41588-021-00821-2  0.751
2021 He X, Zhu B, Xie W, He Y, Song J, Zhang Y, Sun C, Li H, Tang Q, Sun X, Tan Y, Liu Y. Amelioration of imiquimod-induced psoriasis-like dermatitis in mice by DSW therapy inspired hydrogel. Bioactive Materials. 6: 299-311. PMID 32954049 DOI: 10.1016/j.bioactmat.2020.08.007  0.336
2020 Fu X, Zhang C, Zhang Y. Epigenetic regulation of mouse preimplantation embryo development. Current Opinion in Genetics & Development. 64: 13-20. PMID 32563750 DOI: 10.1016/J.Gde.2020.05.015  0.411
2020 Fu X, Djekidel MN, Zhang Y. A transcriptional roadmap for 2C-like-to-pluripotent state transition. Science Advances. 6: eaay5181. PMID 32523982 DOI: 10.1126/Sciadv.Aay5181  0.734
2020 Chen Z, Zhang Y. Maternal H3K27me3-dependent autosomal and X chromosome imprinting. Nature Reviews. Genetics. PMID 32514155 DOI: 10.1038/S41576-020-0245-9  0.366
2020 McGlynn KA, Sun R, Vonica A, Rudzinskas S, Zhang Y, Perkins AS. Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential. Experimental Hematology. PMID 32437910 DOI: 10.1016/J.Exphem.2020.04.010  0.32
2020 Zhang Y, Zhang M, Lin M, Gephart MH, Veeravagu A, Ratliff JK, Li G. Costs and Complications Associated with Resection of Supratentorial Tumors with and without the Operative Microscope in the United States. World Neurosurgery. PMID 32171932 DOI: 10.1016/j.wneu.2020.03.021  0.309
2020 Zhang C, Chen Z, Yin Q, Fu X, Li Y, Stopka T, Skoultchi AI, Zhang Y. The chromatin remodeler Snf2h is essential for oocyte meiotic cell cycle progression. Genes & Development. PMID 31919188 DOI: 10.1101/Gad.331157.119  0.403
2019 Chen Z, Yin Q, Inoue A, Zhang C, Zhang Y. Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells. Science Advances. 5: eaay7246. PMID 32064321 DOI: 10.1126/Sciadv.Aay7246  0.389
2019 Zhang M, Zhang Y, Zheng E, Gephart MH, Veeravagu A, Desai A, Ratliff JK, Li G. Outcomes and costs following Ommaya placement with thrombocytopenia among US cancer patients. World Neurosurgery. PMID 31866457 DOI: 10.1016/j.wneu.2019.12.063  0.313
2019 Chen Z, Zhang Y. Role of Mammalian DNA Methyltransferases in Development. Annual Review of Biochemistry. PMID 31815535 DOI: 10.1146/Annurev-Biochem-103019-102815  0.35
2019 Bhattacherjee A, Djekidel MN, Chen R, Chen W, Tuesta LM, Zhang Y. Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction. Nature Communications. 10: 4169. PMID 31519873 DOI: 10.1038/S41467-019-12054-3  0.766
2019 Lu X, Chu CS, Fang T, Rayon-Estrada V, Fang F, Patke A, Qian Y, Clarke SH, Melnick AM, Zhang Y, Papavasiliou FN, Roeder RG. MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition. Cell Reports. 28: 472-485.e5. PMID 31291582 DOI: 10.1016/J.Celrep.2019.06.029  0.476
2019 Fu X, Wu X, Djekidel MN, Zhang Y. Myc and Dnmt1 impede the pluripotent to totipotent state transition in embryonic stem cells. Nature Cell Biology. PMID 31209294 DOI: 10.1038/S41556-019-0343-0  0.758
2019 Tuesta LM, Djekidel MN, Chen R, Lu F, Wang W, Sabatini BL, Zhang Y. In vivo nuclear capture and molecular profiling identifies Gmeb1 as a transcriptional regulator essential for dopamine neuron function. Nature Communications. 10: 2508. PMID 31175277 DOI: 10.1038/S41467-019-10267-0  0.748
2019 Chen Z, Zhang Y. Loss of DUX causes minor defects in zygotic genome activation and is compatible with mouse development. Nature Genetics. 51: 947-951. PMID 31133747 DOI: 10.1038/S41588-019-0418-7  0.393
2019 Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, et al. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. Nature Communications. 10: 2314. PMID 31127101 DOI: 10.1038/S41467-019-10324-8  0.467
2019 Zhang W, Chen Z, Yin Q, Zhang D, Racowsky C, Zhang Y. Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula. Genes & Development. PMID 30808660 DOI: 10.1101/Gad.323105.118  0.367
2018 Inoue A, Chen Z, Yin Q, Zhang Y. Maternal knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells. Genes & Development. PMID 30463900 DOI: 10.1101/Gad.318675.118  0.366
2018 Kim H, Kim D, Choi SA, Kim CR, Oh SK, Pyo KE, Kim J, Lee SH, Yoon JB, Zhang Y, Baek SH. KDM3A histone demethylase functions as an essential factor for activation of JAK2-STAT3 signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 30377265 DOI: 10.1073/Pnas.1805662115  0.31
2018 Ayoub E, Wilson MP, McGrath KE, Li AJ, Frisch BJ, Palis J, Calvi LM, Zhang Y, Perkins AS. EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription. Nature Communications. 9: 4239. PMID 30315161 DOI: 10.1038/S41467-018-06208-Y  0.323
2018 Wang Y, Zhou P, Qin S, Xu D, Liu Y, Fu W, Ruan B, Zhang L, Zhang Y, Wang X, Pan Y, Wang S, Yan H, Qin J, Wang X, et al. The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells. Frontiers in Pharmacology. 9: 820. PMID 30186159 DOI: 10.3389/Fphar.2018.00820  0.338
2018 Matoba S, Zhang Y. Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications. Cell Stem Cell. PMID 30033121 DOI: 10.1016/J.Stem.2018.06.018  0.322
2018 Matoba S, Wang H, Jiang L, Lu F, Iwabuchi KA, Wu X, Inoue K, Yang L, Press W, Lee JT, Ogura A, Shen L, Zhang Y. Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development. Cell Stem Cell. PMID 30033120 DOI: 10.1016/J.Stem.2018.06.008  0.694
2018 Djekidel MN, Inoue A, Matoba S, Suzuki T, Zhang C, Lu F, Jiang L, Zhang Y. Reprogramming of Chromatin Accessibility in Somatic Cell Nuclear Transfer Is DNA Replication Independent. Cell Reports. 23: 1939-1947. PMID 29768195 DOI: 10.1016/J.Celrep.2018.04.036  0.786
2017 Inoue A, Jiang L, Lu F, Zhang Y. Genomic imprinting of Xist by maternal H3K27me3. Genes & Development. 31: 1927-1932. PMID 29089420 DOI: 10.1101/Gad.304113.117  0.664
2017 Zhang J, Geng Y, Guo F, Zhang F, Liu M, Song L, Ma Y, Li D, Zhang Y, Xu H, Yang H. Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu. Scientific Reports. 7: 13867. PMID 29066842 DOI: 10.1038/S41598-017-10131-5  0.304
2017 Lee CC, Peng SH, Shen L, Lee CF, Du TH, Kang ML, Xu GL, Upadhyay AK, Cheng X, Yan YT, Zhang Y, Juan LJ. The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting. Molecular Cell. PMID 28943313 DOI: 10.1016/J.Molcel.2017.08.025  0.355
2017 Inoue A, Jiang L, Lu F, Suzuki T, Zhang Y. Maternal H3K27me3 controls DNA methylation-independent imprinting. Nature. PMID 28723896 DOI: 10.1038/Nature23262  0.703
2017 Wu X, Zhang Y. TET-mediated active DNA demethylation: mechanism, function and beyond. Nature Reviews. Genetics. PMID 28555658 DOI: 10.1038/Nrg.2017.33  0.335
2017 Wu X, Inoue A, Suzuki T, Zhang Y. Simultaneous mapping of active DNA demethylation and sister chromatid exchange in single cells. Genes & Development. PMID 28360182 DOI: 10.1101/Gad.294843.116  0.356
2017 Chen R, Wu X, Jiang L, Zhang Y. Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity. Cell Reports. 18: 3227-3241. PMID 28355573 DOI: 10.1016/J.Celrep.2017.03.004  0.405
2017 Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess MR, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, ... Zhang Y, et al. The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. Nature Medicine. PMID 28191887 DOI: 10.1038/Nm.4283  0.305
2017 Perkins AS, Wilson M, Ayoub E, Zhang Y, Kathleen ME, Palis J, Li AJ, Calvi LM. High-Level EVI1 Perturbs Hematopoietic Function By Skewing Cells Towards Myeloid Phenotype Via Induction of PU.1/ Spi1 Â Transcription Blood. 130: 2505-2505. DOI: 10.1182/Blood.V130.Suppl_1.2505.2505  0.337
2016 Tao J, Wu H, Coronado AA, de Laittre E, Osterweil EK, Zhang Y, Bear MF. Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11946-11958. PMID 27881780 DOI: 10.1523/Jneurosci.0672-16.2016  0.354
2016 Kim M, Lu F, Zhang Y. Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer. Cell Reports. 17: 275-88. PMID 27681437 DOI: 10.1016/J.Celrep.2016.09.003  0.657
2016 Lu F, Liu Y, Inoue A, Suzuki T, Zhao K, Zhang Y. Establishing Chromatin Regulatory Landscape during Mouse Preimplantation Development. Cell. 165: 1375-1388. PMID 27259149 DOI: 10.1016/J.Cell.2016.05.050  0.721
2016 Zhang Y, Ran Y, Xiong Y, Zhong ZB, Wang ZH, Fan XL, Ye QF. Effects of TMEM9 gene on cell progression in hepatocellular carcinoma by RNA interference. Oncology Reports. PMID 27220462 DOI: 10.3892/Or.2016.4821  0.304
2016 Wu H, Wu X, Zhang Y. Base-resolution profiling of active DNA demethylation using MAB-seq and caMAB-seq. Nature Protocols. 11: 1081-1100. PMID 27172168 DOI: 10.1038/Nprot.2016.069  0.316
2016 Wilson M, Tsakraklides V, Tran M, Xiao YY, Zhang Y, Perkins AS. EVI1 interferes with myeloid maturation via transcriptional repression of Cebpa, via binding to two far downstream regulatory elements. The Journal of Biological Chemistry. PMID 27129260 DOI: 10.1074/Jbc.M115.708156  0.383
2016 Yao J, Leng L, Sauler M, Fu W, Zheng J, Zhang Y, Du X, Yu X, Lee P, Bucala R. Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus. The Journal of Clinical Investigation. PMID 26752645 DOI: 10.1172/Jci81937  0.347
2015 Jiang H, Xu Z, Zhong P, Ren Y, Liang G, Schilling HA, Hu Z, Zhang Y, Wang X, Chen S, Yan Z, Feng J. Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons. Nature Communications. 6: 10100. PMID 26639555 DOI: 10.1038/Ncomms10100  0.341
2015 Chung YG, Matoba S, Liu Y, Eum JH, Lu F, Jiang W, Lee JE, Sepilian V, Cha KY, Lee DR, Zhang Y. Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells. Cell Stem Cell. PMID 26526725 DOI: 10.1016/J.Stem.2015.10.001  0.698
2015 Yardimci H, Zhang Y. Charting oxidized methylcytosines at base resolution. Nature Structural & Molecular Biology. 22: 656-61. PMID 26333715 DOI: 10.1038/Nsmb.3071  0.307
2015 Cao Y, Zhang S, Yuan N, Wang J, Li X, Xu F, Lin W, Song L, Fang Y, Wang Z, Wang Z, Zhang H, Zhang Y, Zhao W, Hu S, et al. Hierarchal autophagic divergence of hematopoietic system. The Journal of Biological Chemistry. PMID 26245898 DOI: 10.1074/Jbc.M115.650028  0.322
2015 Lu F, Zhang Y. Cell totipotency: molecular features, induction, and maintenance. National Science Review. 2: 217-225. PMID 26114010 DOI: 10.1093/Nsr/Nwv009  0.696
2015 Jiang W, Liu Y, Liu R, Zhang K, Zhang Y. The lncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression. Cell Reports. 11: 137-48. PMID 25843708 DOI: 10.1016/J.Celrep.2015.03.008  0.373
2015 Inoue A, Shen L, Matoba S, Zhang Y. Haploinsufficiency, but not defective paternal 5mC oxidation, accounts for the developmental defects of maternal Tet3 knockouts. Cell Reports. 10: 463-70. PMID 25640176 DOI: 10.1016/J.Celrep.2014.12.049  0.309
2014 Matoba S, Liu Y, Lu F, Iwabuchi KA, Shen L, Inoue A, Zhang Y. Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation. Cell. 159: 884-95. PMID 25417163 DOI: 10.1016/J.Cell.2014.09.055  0.714
2014 Wu H, Wu X, Shen L, Zhang Y. Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing. Nature Biotechnology. 32: 1231-40. PMID 25362244 DOI: 10.1038/Nbt.3073  0.319
2014 Shen L, Inoue A, He J, Liu Y, Lu F, Zhang Y. Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes. Cell Stem Cell. 15: 459-70. PMID 25280220 DOI: 10.1016/J.Stem.2014.09.002  0.668
2014 Lu F, Liu Y, Jiang L, Yamaguchi S, Zhang Y. Role of Tet proteins in enhancer activity and telomere elongation. Genes & Development. 28: 2103-19. PMID 25223896 DOI: 10.1101/Gad.248005.114  0.703
2014 Inoue A, Zhang Y. Nucleosome assembly is required for nuclear pore complex assembly in mouse zygotes. Nature Structural & Molecular Biology. 21: 609-16. PMID 24908396 DOI: 10.1038/Nsmb.2839  0.351
2014 Shen L, Song CX, He C, Zhang Y. Mechanism and function of oxidative reversal of DNA and RNA methylation. Annual Review of Biochemistry. 83: 585-614. PMID 24905787 DOI: 10.1146/Annurev-Biochem-060713-035513  0.353
2014 Li E, Zhang Y. DNA Methylation in Mammals Cold Spring Harbor Perspectives in Biology. 6. PMID 24789823 DOI: 10.1101/Cshperspect.A019133  0.385
2014 Tuesta LM, Zhang Y. Mechanisms of epigenetic memory and addiction. The Embo Journal. 33: 1091-103. PMID 24778453 DOI: 10.1002/Embj.201488106  0.764
2014 Li X, Wei W, Zhao QY, Widagdo J, Baker-Andresen D, Flavell CR, D'Alessio A, Zhang Y, Bredy TW. Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7120-5. PMID 24757058 DOI: 10.1073/Pnas.1318906111  0.354
2014 Bard-Chapeau EA, Szumska D, Jacob B, Chua BQ, Chatterjee GC, Zhang Y, Ward JM, Urun F, Kinameri E, Vincent SD, Ahmed S, Bhattacharya S, Osato M, Perkins AS, Moore AW, et al. Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects. Plos One. 9: e89397. PMID 24586749 DOI: 10.1371/Journal.Pone.0089397  0.337
2014 Glass C, Wilson M, Gonzalez R, Zhang Y, Perkins AS. The role of EVI1 in myeloid malignancies. Blood Cells, Molecules & Diseases. 53: 67-76. PMID 24495476 DOI: 10.1016/J.Bcmd.2014.01.002  0.356
2014 Wu H, Zhang Y. Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions Cell. 156: 45-68. PMID 24439369 DOI: 10.1016/J.Cell.2013.12.019  0.353
2014 Wang Y, Zhang Y. Regulation of TET protein stability by calpains Cell Reports. 6: 278-284. PMID 24412366 DOI: 10.1016/J.Celrep.2013.12.031  0.373
2014 Yue D, Fan Q, Chen X, Li F, Wang L, Huang L, Dong W, Chen X, Zhang Z, Liu J, Wang F, Wang M, Zhang B, Zhang Y. Epigenetic inactivation of SPINT2 is associated with tumor suppressive function in esophageal squamous cell carcinoma. Experimental Cell Research. 322: 149-58. PMID 24269829 DOI: 10.1016/J.Yexcr.2013.11.009  0.335
2013 Yamaguchi S, Shen L, Liu Y, Sendler D, Zhang Y. Role of Tet1 in erasure of genomic imprinting. Nature. 504: 460-4. PMID 24291790 DOI: 10.1038/Nature12805  0.375
2013 Kohli RM, Zhang Y. TET enzymes, TDG and the dynamics of DNA demethylation. Nature. 502: 472-9. PMID 24153300 DOI: 10.1038/Nature12750  0.332
2013 Jiang W, Zhang D, Bursac N, Zhang Y. WNT3 is a biomarker capable of predicting the definitive endoderm differentiation potential of hESCs. Stem Cell Reports. 1: 46-52. PMID 24052941 DOI: 10.1016/J.Stemcr.2013.03.003  0.324
2013 Zhang Y, Owens K, Hatem L, Glass CH, Karuppaiah K, Camargo F, Perkins AS. Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia. Blood. 122: 2888-92. PMID 24021671 DOI: 10.1182/Blood-2012-08-453662  0.311
2013 Glass C, Wuertzer C, Cui X, Bi Y, Davuluri R, Xiao YY, Wilson M, Owens K, Zhang Y, Perkins A. Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia. Plos One. 8: e67134. PMID 23826213 DOI: 10.1371/Journal.Pone.0067134  0.352
2013 Lin FJ, Shen L, Jang CW, Falnes PØ, Zhang Y. Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression. Plos Genetics. 9: e1003516. PMID 23717213 DOI: 10.1371/Journal.Pgen.1003516  0.354
2013 Shen L, Wu H, Diep D, Yamaguchi S, D'Alessio AC, Fung HL, Zhang K, Zhang Y. Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell. 153: 692-706. PMID 23602152 DOI: 10.1016/J.Cell.2013.04.002  0.321
2013 He J, Shen L, Wan M, Taranova O, Wu H, Zhang Y. Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes. Nature Cell Biology. 15: 373-84. PMID 23502314 DOI: 10.1038/Ncb2702  0.4
2013 Yamaguchi S, Hong K, Liu R, Inoue A, Shen L, Zhang K, Zhang Y. Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Cell Research. 23: 329-39. PMID 23399596 DOI: 10.1038/Cr.2013.22  0.382
2013 Liang G, Zhang Y. Embryonic stem cell and induced pluripotent stem cell: An epigenetic perspective Cell Research. 23: 49-69. PMID 23247625 DOI: 10.1038/Cr.2012.175  0.342
2013 Jiang W, Wang J, Zhang Y. Histone H3K27me3 demethylases KDM6A and KDM6B modulate definitive endoderm differentiation from human ESCs by regulating WNT signaling pathway Cell Research. 23: 122-130. PMID 22907667 DOI: 10.1038/Cr.2012.119  0.327
2013 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y. 5mC and 5hmC dynamics during PGC reprogramming and role of Tet1 in female meiosis Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P89  0.402
2013 Shen L, Wu H, Diep D, D’Alessio AC, Fung A, Zhang K, Zhang Y. Genome-wide analysis reveals TET-and TDG-mediated 5-methylcytosine oxidation dynamics Epigenetics & Chromatin. 6: P88. DOI: 10.1186/1756-8935-6-S1-P88  0.364
2013 Zhang Y, Cui X, Wuertzer CA, Perkins AS. EVI1, A Potential Regulator Of CEBPA; A Contributory Mechanism In Leukemogenesis? Blood. 122: 2495-2495. DOI: 10.1182/Blood.V122.21.2495.2495  0.354
2013 Ling D, Tee A, Nelson C, Xu N, Atmadibrata B, Liu PY, Pasquier E, Marshall GM, Suzuki T, Zhang Y, Liu T. Abstract 2985: The histone demethylase JMJD1A induces neuroblastoma cell migration and invasion. Cancer Research. 73: 2985-2985. DOI: 10.1158/1538-7445.Am2013-2985  0.376
2012 Wan M, Liang J, Xiong Y, Shi F, Zhang Y, Lu W, He Q, Yang D, Chen R, Liu D, Barton M, Songyang Z. The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells. The Journal of Biological Chemistry. 288: 5039-48. PMID 23239880 DOI: 10.1074/Jbc.M112.424515  0.329
2012 Inoue A, Matoba S, Zhang Y. Transcriptional activation of transposable elements in mouse zygotes is independent of Tet3-mediated 5-methylcytosine oxidation. Cell Research. 22: 1640-9. PMID 23184059 DOI: 10.1038/Cr.2012.160  0.356
2012 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y. Tet1 controls meiosis by regulating meiotic gene expression. Nature. 492: 443-7. PMID 23151479 DOI: 10.1038/Nature11709  0.43
2012 Shen L, Zhang Y. Enzymatic analysis of Tet proteins: key enzymes in the metabolism of DNA methylation. Methods in Enzymology. 512: 93-105. PMID 22910204 DOI: 10.1016/B978-0-12-391940-3.00005-6  0.318
2012 Nabel CS, Jia H, Ye Y, Shen L, Goldschmidt HL, Stivers JT, Zhang Y, Kohli RM. AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation. Nature Chemical Biology. 8: 751-8. PMID 22772155 DOI: 10.1038/Nchembio.1042  0.337
2012 Adelmant G, Calkins AS, Garg BK, Card JD, Askenazi M, Miron A, Sobhian B, Zhang Y, Nakatani Y, Silver PA, Iglehart JD, Marto JA, Lazaro JB. DNA ends alter the molecular composition and localization of Ku multicomponent complexes. Molecular & Cellular Proteomics : McP. 11: 411-21. PMID 22535209 DOI: 10.1074/Mcp.M111.013581  0.335
2012 Liang G, He J, Zhang Y. Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming Nature Cell Biology. 14: 457-466. PMID 22522173 DOI: 10.1038/Ncb2483  0.388
2012 Yan W, Liu S, Xu E, Zhang J, Zhang Y, Chen X, Chen X. Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8 Oncogene. 32: 599-609. DOI: 10.1038/Onc.2012.81  0.325
2012 Liang G, He J, Zhang Y. Erratum: Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming (Nature Cell Biology (2012) 14 (457-466)) Nature Cell Biology. 14. DOI: 10.1038/Ncb2518  0.334
2012 Wu H, Zhang Y. Early embryos reprogram DNA methylation in two steps Cell Stem Cell. 10: 487-489. DOI: 10.1016/J.Stem.2012.04.012  0.325
2011 Wu H, Zhang Y. Mechanisms and functions of Tet proteinmediated 5-methylcytosine oxidation Genes and Development. 25: 2436-2452. PMID 22156206 DOI: 10.1101/Gad.179184.111  0.414
2011 Inoue A, Shen L, Dai Q, He C, Zhang Y. Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Research. 21: 1670-6. PMID 22124233 DOI: 10.1038/Cr.2011.189  0.338
2011 Zhang Y, Wheatley R, Fulkerson E, Tapp A, Estes PA. Mastermind mutations generate a unique constellation of midline cells within the Drosophila CNS. Plos One. 6: e26197. PMID 22046261 DOI: 10.1371/Journal.Pone.0026197  0.354
2011 Zhang Y, Sicot G, Cui X, Vogel M, Wuertzer CA, Lezon-Geyda K, Wheeler J, Harki DA, Muzikar KA, Stolper DA, Dervan PB, Perkins AS. Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide. Biochemistry. 50: 10431-41. PMID 22039883 DOI: 10.1021/Bi200962U  0.33
2011 Inoue A, Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science (New York, N.Y.). 334: 194. PMID 21940858 DOI: 10.1126/Science.1212483  0.34
2011 Tao Y, Neppl RL, Huang ZP, Chen J, Tang RH, Cao R, Zhang Y, Jin SW, Wang DZ. The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly. The Journal of Cell Biology. 194: 551-65. PMID 21859860 DOI: 10.1083/Jcb.201010090  0.304
2011 Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science (New York, N.Y.). 333: 1300-3. PMID 21778364 DOI: 10.1126/Science.1210597  0.344
2011 Wu H, Zhang Y. Tet1 and 5-hydroxymethylation: A genome-wide view in mouse embryonic stem cells Cell Cycle. 10: 2428-2436. PMID 21750410 DOI: 10.4161/Cc.10.15.16930  0.408
2011 Nguyen AT, Zhang Y. The diverse functions of Dot1 and H3K79 methylationanh Genes and Development. 25: 1345-1358. PMID 21724828 DOI: 10.1101/Gad.2057811  0.408
2011 Zhang Y, Stehling-Sun S, Lezon-Geyda K, Juneja SC, Coillard L, Chatterjee G, Wuertzer CA, Camargo F, Perkins AS. PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function. Blood. 118: 3853-61. PMID 21666053 DOI: 10.1182/Blood-2011-02-334680  0.347
2011 Wu SC, Zhang Y. Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability. The Journal of Biological Chemistry. 286: 28511-9. PMID 21659531 DOI: 10.1074/Jbc.M111.240515  0.343
2011 Nguyen AT, Taranova O, He J, Zhang Y. DOT1L, the H3K79 methyltransferase, is required for MLL-AF9 - Mediated leukemogenesis Blood. 117: 6912-6922. PMID 21521783 DOI: 10.1182/Blood-2011-02-334359  0.361
2011 Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes & Development. 25: 679-84. PMID 21460036 DOI: 10.1101/Gad.2036011  0.375
2011 Wu H, D'Alessio AC, Ito S, Xia K, Wang Z, Cui K, Zhao K, Sun YE, Zhang Y. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature. 473: 389-93. PMID 21451524 DOI: 10.1038/Nature09934  0.443
2011 Zhang Y. Recent progress in the epigenetics and chromatin field. Cell Research. 21: 373-374. PMID 21383679 DOI: 10.1038/Cr.2011.33  0.415
2011 He J, Nguyen AT, Zhang Y. KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia Blood. 117: 3869-3880. PMID 21310926 DOI: 10.1182/Blood-2010-10-312736  0.382
2011 Nguyen AT, Xiao B, Neppl RL, Kallin EM, Li J, Chen T, Wang DZ, Xiao X, Zhang Y. DOT1L regulates dystrophin expression and is critical for cardiac function. Genes & Development. 25: 263-74. PMID 21289070 DOI: 10.1101/Gad.2018511  0.391
2011 Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, ... ... Zhang Y, et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell. 19: 17-30. PMID 21251613 DOI: 10.1016/J.Ccr.2010.12.014  0.335
2010 Zhang Y, Cheng MB, Zhang YJ, Zhong X, Dai H, Yan L, Wu NH, Zhang Y, Shen YF. A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes. Cell Research. 20: 1345-60. PMID 21079652 DOI: 10.1038/Cr.2010.155  0.329
2010 Wu SC, Zhang Y. Active DNA demethylation: many roads lead to Rome Nature Reviews Molecular Cell Biology. 11: 607-620. PMID 20683471 DOI: 10.1038/Nrm2950  0.37
2010 Wu SC, Kallin EM, Zhang Y. Role of H3K27 methylation in the regulation of lncRNA expression. Cell Research. 20: 1109-16. PMID 20680032 DOI: 10.1038/Cr.2010.114  0.396
2010 Wu H, Coskun V, Tao J, Xie W, Ge W, Yoshikawa K, Li E, Zhang Y, Sun YE. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science (New York, N.Y.). 329: 444-8. PMID 20651149 DOI: 10.1126/Science.1190485  0.392
2010 Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature. 466: 1129-33. PMID 20639862 DOI: 10.1038/Nature09303  0.4
2010 Liang G, Taranova O, Xia K, Zhang Y. Butyrate promotes induced pluripotent stem cell generation. Journal of Biological Chemistry. 285: 25516-25521. PMID 20554530 DOI: 10.1074/Jbc.M110.142059  0.394
2010 Tanaka Y, Okamoto K, Teye K, Umata T, Yamagiwa N, Suto Y, Zhang Y, Tsuneoka M. JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation The Embo Journal. 29: 1510-1522. PMID 20379134 DOI: 10.1038/Emboj.2010.56  0.323
2010 Yang Z, Jiang J, Stewart DM, Qi S, Yamane K, Li J, Zhang Y, Wong J. AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function Cell Research. 20: 276-287. PMID 20101264 DOI: 10.1038/Cr.2010.12  0.391
2010 An JY, Kim EA, Jiang Y, Zakrzewska A, Kim DE, Lee MJ, Mook-Jung I, Zhang Y, Kwon YT. UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 107: 1912-7. PMID 20080676 DOI: 10.1073/Pnas.0910267107  0.384
2010 Okada Y, Yamagata K, Hong K, Wakayama T, Zhang Y. A role for the elongator complex in zygotic paternal genome demethylation Nature. 463: 554-558. PMID 20054296 DOI: 10.1038/Nature08732  0.392
2010 He J, Zhang Y. Janus Kinase 2: An Epigenetic ‘Writer’ that Activates Leukemogenic Genes Journal of Molecular Cell Biology. 2: 231-233. PMID 20051435 DOI: 10.1093/Jmcb/Mjp054  0.325
2010 Okada Y, Tateishi K, Zhang Y. Histone demethylase JHDM2A is involved in male infertility and obesity. Journal of Andrology. 31: 75-78. PMID 19875498 DOI: 10.2164/Jandrol.109.008052  0.404
2009 Lu T, Jackson MW, Singhi AD, Kandel ES, Yang M, Zhang Y, Gudkov AV, Stark GR. Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proceedings of the National Academy of Sciences of the United States of America. 106: 16339-44. PMID 19805303 DOI: 10.1073/Pnas.0908560106  0.382
2009 Kallin EM, Cao R, Jothi R, Xia K, Cui K, Zhao K, Zhang Y. Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes. Plos Genetics. 5: e1000506. PMID 19503595 DOI: 10.1371/Journal.Pgen.1000506  0.403
2009 Lin YH, Kakadia PM, Chen Y, Li YQ, Deshpande AJ, Buske C, Zhang KL, Zhang Y, Xu GL, Bohlander SK. Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias. Blood. 114: 651-8. PMID 19443658 DOI: 10.1182/Blood-2009-03-209395  0.337
2009 Wu SC, Zhang Y. Minireview: Role of protein methylation and demethylation in nuclear hormone signaling Molecular Endocrinology. 23: 1323-1334. PMID 19407220 DOI: 10.1210/Me.2009-0131  0.387
2009 Ficarro SB, Zhang Y, Lu Y, Moghimi AR, Askenazi M, Hyatt E, Smith ED, Boyer L, Schlaeger TM, Luckey CJ, Marto JA. Improved electrospray ionization efficiency compensates for diminished chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells. Analytical Chemistry. 81: 3440-7. PMID 19331382 DOI: 10.1021/Ac802720E  0.302
2009 Tateishi K, Okada Y, Kallin EM, Zhang Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature. 458: 757-61. PMID 19194461 DOI: 10.1038/Nature07777  0.353
2009 Lee N, Erdjument-Bromage H, Tempst P, Jones RS, Zhang Y. The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3. Molecular and Cellular Biology. 29: 1401-10. PMID 19114561 DOI: 10.1128/Mcb.01643-08  0.37
2008 He J, Kallin EM, Tsukada Y, Zhang Y. The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b). Nature Structural & Molecular Biology. 15: 1169-75. PMID 18836456 DOI: 10.1038/Nsmb.1499  0.333
2008 Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. Plos Genetics. 4: e1000190. PMID 18787701 DOI: 10.1371/Journal.Pgen.1000190  0.398
2008 Lee N, Zhang Y. Chemical answers to epigenetic crosstalk. Nature Chemical Biology. 4: 335-7. PMID 18488009 DOI: 10.1038/Nchembio0608-335  0.365
2008 Lu X, Kovalev GI, Chang H, Kallin E, Knudsen G, Xia L, Mishra N, Ruiz P, Li E, Su L, Zhang Y. Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. The Journal of Biological Chemistry. 283: 13825-33. PMID 18353770 DOI: 10.1074/Jbc.M801275200  0.32
2008 Estes P, Fulkerson E, Zhang Y. Identification of motifs that are conserved in 12 Drosophila species and regulate midline glia vs. neuron expression. Genetics. 178: 787-99. PMID 18245363 DOI: 10.1534/Genetics.107.080440  0.373
2008 Cao R, Wang H, He J, Erdjument-Bromage H, Tempst P, Zhang Y. Role of hPHF1 in H3K27 methylation and Hox gene silencing. Molecular and Cellular Biology. 28: 1862-72. PMID 18086877 DOI: 10.1128/Mcb.01589-07  0.38
2008 Perkins AS, Campo JJd, Xiao Y, Zhang Y, Lin SJ, Dudley J, Tuck D, Yatsula B. EVI1 Blocks Apoptosis in DA-1 Myeloid Leukemia Cells Via Enhanced Transcription of the Prosurvival Gene Bcl2a1 (A1) Blood. 112: 3805-3805. DOI: 10.1182/Blood.V112.11.3805.3805  0.329
2008 Sicot G, Vogel M, Zhang Y, Harki DA, Lezon-Geyda K, Dervan P, Perkins AS. Development of a Novel Polyamide-Based Agent to Inhibit EVI1 Function Blood. 112: 2660-2660. DOI: 10.1182/Blood.V112.11.2660.2660  0.317
2007 Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y. New nomenclature for chromatin-modifying enzymes. Cell. 131: 633-6. PMID 18022353 DOI: 10.1016/J.Cell.2007.10.039  0.477
2007 Klose RJ, Zhang Y. Histone H3 Arg2 methylation provides alternative directions for COMPASS. Nature Structural & Molecular Biology. 14: 1058-1060. PMID 17984969 DOI: 10.1038/Nsmb1107-1058  0.352
2007 Okada Y, Scott G, Ray MK, Mishina Y, Zhang Y. Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis Nature. 450: 119-123. PMID 17943087 DOI: 10.1038/Nature06236  0.391
2007 Fang J, Hogan GJ, Liang G, Lieb JD, Zhang Y. The Saccharomyces cerevisiae histone demethylase Jhd1 fine-tunes the distribution of H3K36me2. Molecular and Cellular Biology. 27: 5055-65. PMID 17470555 DOI: 10.1128/Mcb.00127-07  0.383
2007 Li ZY, Yang J, Gao X, Lu JY, Zhang Y, Wang K, Cheng MB, Wu NH, Zhang Y, Wu Z, Shen YF. Sequential recruitment of PCAF and BRG1 contributes to myogenin activation in 12-O-tetradecanoylphorbol-13-acetate-induced early differentiation of rhabdomyosarcoma-derived cells. The Journal of Biological Chemistry. 282: 18872-8. PMID 17468105 DOI: 10.1074/Jbc.M609448200  0.41
2007 Martin C, Zhang Y. Mechanisms of epigenetic inheritance. Current Opinion in Cell Biology. 19: 266-272. PMID 17466502 DOI: 10.1016/J.Ceb.2007.04.002  0.409
2007 Klose RJ, Gardner KE, Liang G, Erdjument-Bromage H, Tempst P, Zhang Y. Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae? Molecular and Cellular Biology. 27: 3951-61. PMID 17371840 DOI: 10.1128/Mcb.02180-06  0.382
2007 Yamane K, Tateishi K, Klose RJ, Fang J, Fabrizio LA, Erdjument-Bromage H, Taylor-Papadimitriou J, Tempst P, Zhang Y. PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Molecular Cell. 25: 801-12. PMID 17363312 DOI: 10.1016/J.Molcel.2007.03.001  0.38
2007 Lee N, Zhang J, Klose RJ, Erdjument-Bromage H, Tempst P, Jones RS, Zhang Y. The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase. Nature Structural & Molecular Biology. 14: 341-3. PMID 17351631 DOI: 10.1038/Nsmb1216  0.382
2007 Klose RJ, Zhang Y. Regulation of histone methylation by demethylimination and demethylation. Nature Reviews Molecular Cell Biology. 8: 307-318. PMID 17342184 DOI: 10.1038/Nrm2143  0.373
2007 Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y, Kaelin WG. The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell. 128: 889-900. PMID 17320163 DOI: 10.1016/J.Cell.2007.02.013  0.422
2007 Liang G, Klose RJ, Gardner KE, Zhang Y. Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nature Structural & Molecular Biology. 14: 243-5. PMID 17310254 DOI: 10.1038/Nsmb1204  0.364
2007 Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. Genes & Development. 21: 49-54. PMID 17210787 DOI: 10.1101/Gad.1499407  0.335
2006 Tsukada Y, Zhang Y. Purification of histone demethylases from HeLa cells. Methods (San Diego, Calif.). 40: 318-26. PMID 17101443 DOI: 10.1016/J.Ymeth.2006.06.024  0.386
2006 Klose RJ, Kallin EM, Zhang Y. JmjC-domain-containing proteins and histone demethylation. Nature Reviews. Genetics. 7: 715-27. PMID 16983801 DOI: 10.1038/Nrg1945  0.395
2006 Bender LB, Suh J, Carroll CR, Fong Y, Fingerman IM, Briggs SD, Cao R, Zhang Y, Reinke V, Strome S. MES-4: an autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line. Development (Cambridge, England). 133: 3907-17. PMID 16968818 DOI: 10.1242/Dev.02584  0.333
2006 Zhang Y. It takes a PHD to interpret histone methylation. Nature Structural & Molecular Biology. 13: 572-574. PMID 16826231 DOI: 10.1038/Nsmb0706-572  0.365
2006 Klose RJ, Yamane K, Bae Y, Zhang D, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature. 442: 312-6. PMID 16732292 DOI: 10.1038/Nature04853  0.382
2006 Li Z, Cao R, Wang M, Myers MP, Zhang Y, Xu RM. Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex. The Journal of Biological Chemistry. 281: 20643-9. PMID 16714294 DOI: 10.1074/Jbc.M602461200  0.311
2006 Wang H, Zhai L, Xu J, Joo HY, Jackson S, Erdjument-Bromage H, Tempst P, Xiong Y, Zhang Y. Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Molecular Cell. 22: 383-94. PMID 16678110 DOI: 10.1016/J.Molcel.2006.03.035  0.322
2006 Yamane K, Toumazou C, Tsukada Y, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell. 125: 483-95. PMID 16603237 DOI: 10.1016/J.Cell.2006.03.027  0.399
2006 Huang Y, Fang J, Bedford MT, Zhang Y, Xu RM. Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science (New York, N.Y.). 312: 748-51. PMID 16601153 DOI: 10.1126/Science.1125162  0.329
2006 Martin C, Cao R, Zhang Y. Substrate preferences of the EZH2 histone methyltransferase complex. Journal of Biological Chemistry. 281: 8365-8370. PMID 16431907 DOI: 10.1074/Jbc.M513425200  0.358
2006 Feldman N, Gerson A, Fang J, Li E, Zhang Y, Shinkai Y, Cedar H, Bergman Y. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nature Cell Biology. 8: 188-94. PMID 16415856 DOI: 10.1038/Ncb1353  0.369
2006 Kim J, Daniel J, Espejo A, Lake A, Krishna M, Xia L, Zhang Y, Bedford MT. Tudor, MBT and chromo domains gauge the degree of lysine methylation. Embo Reports. 7: 397-403. PMID 16415788 DOI: 10.1038/Sj.Embor.7400625  0.338
2006 Tsukada Y, Fang J, Erdjument-Bromage H, Warren ME, Borchers CH, Tempst P, Zhang Y. Histone demethylation by a family of JmjC domain-containing proteins. Nature. 439: 811-6. PMID 16362057 DOI: 10.1038/Nature04433  0.35
2006 Zhang Y, Yeung MN, Liu J, Chau CH, Chan YS, Shum DK. Mapping heparanase expression in the spinal cord of adult rats. The Journal of Comparative Neurology. 494: 345-57. PMID 16320243 DOI: 10.1002/Cne.20811  0.518
2005 Cao R, Tsukada Y, Zhang Y. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Molecular Cell. 20: 845-54. PMID 16359901 DOI: 10.1016/J.Molcel.2005.12.002  0.348
2005 Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nature Reviews Molecular Cell Biology. 6: 838-849. PMID 16261189 DOI: 10.1038/Nrm1761  0.372
2005 de la Cruz CC, Fang J, Plath K, Worringer KA, Nusinow DA, Zhang Y, Panning B. Developmental regulation of Suz 12 localization. Chromosoma. 114: 183-92. PMID 15986205 DOI: 10.1007/S00412-005-0008-6  0.38
2005 Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, Su L, Xu G, Zhang Y. hDOT1L links histone methylation to leukemogenesis. Cell. 121: 167-78. PMID 15851025 DOI: 10.1016/J.Cell.2005.05.021  0.36
2004 Umlauf D, Goto Y, Cao R, Cerqueira F, Wagschal A, Zhang Y, Feil R. Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes. Nature Genetics. 36: 1296-1300. PMID 15516932 DOI: 10.1038/Ng1467  0.392
2004 Fang J, Chen T, Chadwick B, Li E, Zhang Y. Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation. The Journal of Biological Chemistry. 279: 52812-5. PMID 15509584 DOI: 10.1074/Jbc.C400493200  0.373
2004 Zhang Y. Molecular biology: no exception to reversibility. Nature. 431: 637-639. PMID 15470410 DOI: 10.1038/431637A  0.353
2004 Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, Jones RS, Zhang Y. Role of histone H2A ubiquitination in Polycomb silencing. Nature. 431: 873-8. PMID 15386022 DOI: 10.1038/Nature02985  0.369
2004 Bender LB, Cao R, Zhang Y, Strome S. The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans. Current Biology : Cb. 14: 1639-43. PMID 15380065 DOI: 10.1016/J.Cub.2004.08.062  0.356
2004 Cao R, Zhang Y. SUZ12 Is Required for Both the Histone Methyltransferase Activity and the Silencing Function of the EED-EZH2 Complex Molecular Cell. 15: 57-67. PMID 15225548 DOI: 10.1016/J.Molcel.2004.06.020  0.414
2004 Cao R, Zhang Y. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3 Current Opinion in Genetics & Development. 14: 155-164. PMID 15196462 DOI: 10.1016/J.Gde.2004.02.001  0.386
2004 Wang L, Brown JL, Cao R, Zhang Y, Kassis JA, Jones RS. Hierarchical recruitment of polycomb group silencing complexes. Molecular Cell. 14: 637-46. PMID 15175158 DOI: 10.1016/J.Molcel.2004.05.009  0.366
2004 Fang J, Wang H, Zhang Y. Purification of histone methyltransferases from HeLa cells. Methods in Enzymology. 377: 213-26. PMID 14979027 DOI: 10.1016/S0076-6879(03)77012-8  0.365
2003 Zhang SB, Huang J, Zhao H, Zhang Y, Hou CH, Cheng XD, Jiang C, Li MQ, Hu J, Qian RL. The in vitro reconstitution of nucleosome and its binding patterns with HMG1/2 and HMG14/17 proteins. Cell Research. 13: 351-359. PMID 14672558 DOI: 10.1038/Sj.Cr.7290180  0.359
2003 Zhang Y. Transcriptional regulation by histone ubiquitination and deubiquitination Genes & Development. 17: 2733-2740. PMID 14630937 DOI: 10.1101/Gad.1156403  0.362
2003 Wang H, An W, Cao R, Xia L, Erdjument-Bromage H, Chatton B, Tempst P, Roeder RG, Zhang Y. mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Molecular Cell. 12: 475-87. PMID 14536086 DOI: 10.1016/J.Molcel.2003.08.007  0.509
2003 Min J, Zhang Y, Xu R. Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27 Genes & Development. 17: 1823-1828. PMID 12897052 DOI: 10.1101/Gad.269603  0.369
2003 Plath K, Fang J, Mlynarczyk-Evans SK, Cao R, Worringer KA, Wang H, de la Cruz CC, Otte AP, Panning B, Zhang Y. Role of histone H3 lysine 27 methylation in X inactivation. Science (New York, N.Y.). 300: 131-5. PMID 12649488 DOI: 10.1126/Science.1084274  0.331
2003 Min J, Feng Q, Li Z, Zhang Y, Xu R. Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase. Cell. 112: 711-723. PMID 12628190 DOI: 10.1016/S0092-8674(03)00114-4  0.322
2003 Im H, Park C, Feng Q, Johnson KD, Kiekhaefer CM, Choi K, Zhang Y, Bresnick EH. Dynamic regulation of histone H3 methylated at lysine 79 within a tissue-specific chromatin domain. The Journal of Biological Chemistry. 278: 18346-52. PMID 12604594 DOI: 10.1074/Jbc.M300890200  0.342
2003 Feng Q, Zhang Y. The NuRD Complex: Linking Histone Modification to Nucleosome Remodeling Current Topics in Microbiology and Immunology. 274: 269-290. PMID 12596911 DOI: 10.1007/978-3-642-55747-7_10  0.399
2003 Ramsden D, Zhang Y. Everything is E(Z): linking histone methylation to B cell development. Nature Immunology. 4: 101-3. PMID 12555091 DOI: 10.1038/Ni0203-101  0.357
2003 Wood A, Krogan NJ, Dover J, Schneider J, Heidt J, Boateng MA, Dean K, Golshani A, Zhang Y, Greenblatt JF, Johnston M, Shilatifard A. Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Molecular Cell. 11: 267-74. PMID 12535539 DOI: 10.1016/S1097-2765(02)00802-X  0.375
2002 Iratni R, Yan YT, Chen C, Ding J, Zhang Y, Price SM, Reinberg D, Shen MM. Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1 Science. 298: 1996-1999. PMID 12471260 DOI: 10.1126/Science.1073405  0.536
2002 Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, Jones RS, Zhang Y. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science (New York, N.Y.). 298: 1039-43. PMID 12351676 DOI: 10.1126/Science.1076997  0.364
2002 Ng HH, Xu RM, Zhang Y, Struhl K. Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79. The Journal of Biological Chemistry. 277: 34655-7. PMID 12167634 DOI: 10.1074/Jbc.C200433200  0.347
2002 Feng Q, Wang H, Ng HH, Erdjument-Bromage H, Tempst P, Struhl K, Zhang Y. Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain. Current Biology : Cb. 12: 1052-8. PMID 12123582 DOI: 10.1016/S0960-9822(02)00901-6  0.352
2002 Fang J, Feng Q, Ketel CS, Wang H, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Simon JA, Zhang Y. Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase. Current Biology : Cb. 12: 1086-99. PMID 12121615 DOI: 10.1016/S0960-9822(02)00924-7  0.356
2002 Ng HH, Feng Q, Wang H, Erdjument-Bromage H, Tempst P, Zhang Y, Struhl K. Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association. Genes & Development. 16: 1518-27. PMID 12080090 DOI: 10.1101/Gad.1001502  0.365
2002 Yang L, Xia L, Wu DY, Wang H, Chansky HA, Schubach WH, Hickstein DD, Zhang Y. Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor. Oncogene. 21: 148-52. PMID 11791185 DOI: 10.1038/Sj.Onc.1204998  0.392
2002 Kuzmichev A, Zhang Y, Erdjument-Bromage H, Tempst P, Reinberg D. Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1). Molecular and Cellular Biology. 22: 835-48. PMID 11784859 DOI: 10.1128/Mcb.22.3.835-848.2002  0.545
2002 Feng Q, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Zhang Y. Identification and Functional Characterization of the p66/p68 Components of the MeCP1 Complex Molecular and Cellular Biology. 22: 536-546. PMID 11756549 DOI: 10.1128/Mcb.22.2.536-546.2002  0.35
2001 Wang H, Cao R, Xia L, Erdjument-Bromage H, Borchers C, Tempst P, Zhang Y. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase Molecular Cell. 8: 1207-1217. PMID 11779497 DOI: 10.1016/S1097-2765(01)00405-1  0.305
2001 Zhang Y, Reinberg D. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes & Development. 15: 2343-60. PMID 11562345 DOI: 10.1101/Gad.927301  0.523
2001 Wang H, Zhang Y. Mi2, an auto-antigen for dermatomyositis, is an ATP-dependent nucleosome remodeling factor. Nucleic Acids Research. 29: 2517-2521. PMID 11410659 DOI: 10.1093/Nar/29.12.2517  0.378
2001 Wang H, Huang ZQ, Xia L, Feng Q, Erdjument-Bromage H, Strahl BD, Briggs SD, Allis CD, Wong J, Tempst P, Zhang Y. Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor Science. 293: 853-857. PMID 11387442 DOI: 10.1126/Science.1060781  0.369
2001 Xia L, Zhang Y. Sp1 and ETS family transcription factors regulate the mouse Mta2 gene expression Gene. 268: 77-85. PMID 11368903 DOI: 10.1016/S0378-1119(01)00429-2  0.403
2001 Lai A, Kennedy BK, Barbie DA, Bertos NR, Yang XJ, Theberge MC, Tsai SC, Seto E, Zhang Y, Kuzmichev A, Lane WS, Reinberg D, Harlow E, Branton PE. RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest. Molecular and Cellular Biology. 21: 2918-32. PMID 11283269 DOI: 10.1128/Mcb.21.8.2918-2932.2001  0.571
2000 Fong CW, Zhang Y, Neo SY, Lin S. Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner. Biochemical Journal. 352: 747-753. DOI: 10.1042/Bj3520747  0.307
1999 Ng HH, Zhang Y, Hendrich B, Johnson CA, Turner BM, Erdjument-Bromage H, Tempst P, Reinberg D, Bird A. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nature Genetics. 23: 58-61. PMID 10471499 DOI: 10.1038/12659  0.584
1999 Zhang Y, Ng HH, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes & Development. 13: 1924-35. PMID 10444591 DOI: 10.1101/Gad.13.15.1924  0.56
1998 Zhang Y, LeRoy G, Seelig HP, Lane WS, Reinberg D. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities Cell. 95: 279-289. PMID 9790534 DOI: 10.1016/S0092-8674(00)81758-4  0.559
1998 Sun X, Zhang Y, Cho H, Rickert P, Lees E, Lane W, Reinberg D. NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription. Molecular Cell. 2: 213-22. PMID 9734358 DOI: 10.1016/S1097-2765(00)80131-8  0.53
1998 Zhang Y, Sun ZW, Iratni R, Erdjument-Bromage H, Tempst P, Hampsey M, Reinberg D. SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. Molecular Cell. 1: 1021-31. PMID 9651585 DOI: 10.1016/S1097-2765(00)80102-1  0.56
1997 Zhang Y, Lin S. Molecular characterization of the cyclin-dependent kinase inhibitor p27 promoter Biochimica Et Biophysica Acta. 1353: 307-318. PMID 9349726 DOI: 10.1016/S0167-4781(97)00063-8  0.313
1997 Zhang Y, Iratni R, Erdjument-Bromage H, Tempst P, Reinberg D. Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell. 89: 357-64. PMID 9150135 DOI: 10.1016/S0092-8674(00)80216-0  0.568
1994 Coats SR, Zhang Y, Epstein LM. Transcription of satellite 2 DNA from the newt is drivev by a snRNA type of promoter Nucleic Acids Research. 22: 4697-4704. PMID 7984420 DOI: 10.1093/Nar/22.22.4697  0.343
Show low-probability matches.