R Benjamin Free - Related publications

Affiliations: 
2003- National Institutes of Health, Bethesda, MD 
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
18 most relevant papers in past 60 days:
Year Citation  Score
2021 Feng Y, Lu Y. Immunomodulatory Effects of Dopamine in Inflammatory Diseases. Frontiers in Immunology. 12: 663102. PMID 33897712 DOI: 10.3389/fimmu.2021.663102   
2021 Kampen S, Duc Vo D, Zhang X, Panel N, Yang Y, Jaiteh M, Matricon P, Svenningsson P, Brea J, Loza MI, Kihlberg J, Carlsson J. Structure-guided Design of G Protein-coupled Receptor Polypharmacology. Angewandte Chemie (International Ed. in English). PMID 33904641 DOI: 10.1002/anie.202101478   
2021 Qian M, Ricarte A, Wouters E, Dalton JAR, Risseeuw MDP, Giraldo J, Van Calenbergh S. Discovery of a true bivalent dopamine D receptor agonist. European Journal of Medicinal Chemistry. 212: 113151. PMID 33450620 DOI: 10.1016/j.ejmech.2020.113151   
2021 Hayatshahi HS, Luedtke RR, Taylor M, Chen PJ, Blass BE, Liu J. Factors Governing Selectivity of Dopamine Receptor Binding Compounds for D2R and D3R Subtypes. Journal of Chemical Information and Modeling. PMID 33988991 DOI: 10.1021/acs.jcim.1c00036   
2021 Rodriguez-Contreras D, Condon AF, Buck DC, Asad N, Dore TM, Verbeek DS, Tijssen MAJ, Shinde U, Williams JT, Neve KA. Signaling-Biased and Constitutively Active Dopamine D2 Receptor Variant. Acs Chemical Neuroscience. PMID 33974399 DOI: 10.1021/acschemneuro.0c00712   
2021 Shivnaraine RV, Kelly B, Elmslie G, Huang XP, Dong YJ, Seidenberg M, Wells JW, Ellis J. Allostery of atypical modulators at oligomeric G protein-coupled receptors. Scientific Reports. 11: 9265. PMID 33927236 DOI: 10.1038/s41598-021-88399-x   
2021 Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V. Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nature Communications. 12: 2971. PMID 34016973 DOI: 10.1038/s41467-021-23149-1   
2021 Sellami A, Montes M, Lagarde N. Predicting Potential Endocrine Disrupting Chemicals Binding to Estrogen Receptor α (ERα) Using a Pipeline Combining Structure-Based and Ligand-Based in Silico Methods. International Journal of Molecular Sciences. 22. PMID 33799614 DOI: 10.3390/ijms22062846   
2021 Filer CN, Andrews JR, Pounds S, Ullas GV. Tritium labelling of two potent dopamine D receptor agonists at high specific activity. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 172: 109670. PMID 33774322 DOI: 10.1016/j.apradiso.2021.109670   
2021 Hsieh CJ, Riad A, Lee JY, Sahlholm K, Xu K, Luedtke RR, Mach RH. Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods. Biomolecules. 11. PMID 33918451 DOI: 10.3390/biom11040529   
2021 Ferré S, Guitart X, Quiroz C, Rea W, García-Malo C, Garcia-Borreguero D, Allen RP, Earley CJ. Akathisia and Restless Legs Syndrome: Solving the Dopaminergic Paradox. Sleep Medicine Clinics. 16: 249-267. PMID 33985651 DOI: 10.1016/j.jsmc.2021.02.012   
2021 Amundarain MJ, Caffarena ER, Costabel MD. How does αHistidine102 affect the binding of modulators to αβγ GABA receptors? molecular insights from experiments. Physical Chemistry Chemical Physics : Pccp. 23: 3993-4006. PMID 33554986 DOI: 10.1039/d0cp05081d   
2021 Manning JJ, Green HM, Glass M, Finlay DB. Pharmacological Selection of Cannabinoid Receptor Effectors: Signalling, Allosteric Modulation and Bias. Neuropharmacology. 108611. PMID 34000272 DOI: 10.1016/j.neuropharm.2021.108611   
2021 Lu JJ, Polgar WE, Mann A, Dasgupta P, Schulz S, Zaveri NT. Differential In vitro Pharmacological Profiles of Structurally Diverse Nociceptin Receptor Agonists in Activating G-protein and Beta-arrestin Signaling at the Human Nociceptin Opioid Receptor. Molecular Pharmacology. PMID 33958480 DOI: 10.1124/molpharm.120.000076   
2021 Gohda K, Iguchi Y, Masuda A, Fujimori K, Yamashita Y, Teno N. Design and identification of a new farnesoid X receptor (FXR) partial agonist by computational structure-activity relationship analysis: Ligand-induced H8 helix fluctuation in the ligand-binding domain of FXR may lead to partial agonism. Bioorganic & Medicinal Chemistry Letters. 41: 128026. PMID 33839252 DOI: 10.1016/j.bmcl.2021.128026   
2021 Egyed A, Kelemen ÁA, Vass M, Visegrády A, Thee SA, Wang Z, de Graaf C, Brea J, Loza MI, Leurs R, Keserű GM. Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule. Bioorganic Chemistry. 111: 104832. PMID 33826962 DOI: 10.1016/j.bioorg.2021.104832   
2021 Belkacemi L, Zhong W, Darmani NA. Signal transduction pathways involved in dopamine D receptor-evoked emesis in the least shrew (Cryptotis parva). Autonomic Neuroscience : Basic & Clinical. 233: 102807. PMID 33865060 DOI: 10.1016/j.autneu.2021.102807   
2021 Linossi EM, Estevam GO, Oshima M, Fraser JS, Collisson EA, Jura N. State of the structure address on MET receptor activation by HGF. Biochemical Society Transactions. PMID 33860789 DOI: 10.1042/BST20200394