| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2019 | Tian X, Richard A, El-Saadi MW, Bhandari A, Latimer B, Van Savage I, Holmes K, Klein RL, Dwyer D, Goeders NE, Yang XW, Lu XH. Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model. Molecular Psychiatry. PMID 31444475 DOI: 10.1038/S41380-019-0492-3 | 0.526 | |||
| 2018 | Grames MS, Dayton RD, Lu X, Schilke RM, Alexander JS, Orr AW, Barmada SJ, Woolard MD, Klein RL. Gene Transfer Induced Hypercholesterolemia in Amyloid Mice. Journal of Alzheimer's Disease : Jad. PMID 30124449 DOI: 10.3233/Jad-180494 | 0.416 | |||
| 2018 | Richard AD, Tian XL, El-Saadi MW, Lu XH. Erasure of striatal chondroitin sulfate proteoglycan-associated extracellular matrix rescues aging-dependent decline of motor learning. Neurobiology of Aging. 71: 61-71. PMID 30099347 DOI: 10.1016/J.Neurobiolaging.2018.07.008 | 0.338 | |||
| 2018 | Grames MS, Dayton RD, Jackson KL, Richard AD, Lu X, Klein RL. Cre-dependent AAV vectors for highly targeted expression of disease-related proteins and neurodegeneration in the substantia nigra. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701529RR. PMID 29513569 DOI: 10.1096/Fj.201701529Rr | 0.414 | |||
| 2018 | Tian X, Richard A, Bhandari A, Goeders N, Yang W, Lu X. T223. Genetic Dissection of the Cognitive Deficits in a Novel Conditional Bacterial Artificial Chromosome Transgenic Mouse Model of Human VIPR2 Copy Number Variation (CNV) Biological Psychiatry. 83: S215. DOI: 10.1016/J.Biopsych.2018.02.560 | 0.341 | |||
| 2017 | Lu XH, Yang XW. Genetically-directed Sparse Neuronal Labeling in BAC Transgenic Mice through Mononucleotide Repeat Frameshift. Scientific Reports. 7: 43915. PMID 28272512 DOI: 10.1038/Srep43915 | 0.545 | |||
| 2016 | Xu J, Bernstein AM, Wong A, Lu XH, Khoja S, Yang XW, Davies DL, Micevych P, Sofroniew MV, Khakh BS. P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8902-20. PMID 27559172 DOI: 10.1523/Jneurosci.1496-16.2016 | 0.489 | |||
| 2016 | Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, et al. Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice. Nature Neuroscience. PMID 26900923 DOI: 10.1038/Nn.4256 | 0.509 | |||
| 2015 | Veldman MB, Rios-Galdamez Y, Lu XH, Gu X, Qin W, Li S, Yang XW, Lin S. The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model. Molecular Neurodegeneration. 10: 67. PMID 26645399 DOI: 10.1186/S13024-015-0063-2 | 0.494 | |||
| 2015 | Peñagarikano O, Lázaro MT, Lu XH, Gordon A, Dong H, Lam HA, Peles E, Maidment NT, Murphy NP, Yang XW, Golshani P, Geschwind DH. Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism. Science Translational Medicine. 7: 271ra8. PMID 25609168 DOI: 10.1126/Scitranslmed.3010257 | 0.505 | |||
| 2014 | Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, et al. Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease. Science Translational Medicine. 6: 268ra178. PMID 25540325 DOI: 10.1126/Scitranslmed.3010523 | 0.536 | |||
| 2014 | Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease. Nature Medicine. 20: 536-41. PMID 24784230 DOI: 10.1038/Nm.3514 | 0.656 | |||
| 2014 | Haustein MD, Kracun S, Lu XH, Shih T, Jackson-Weaver O, Tong X, Xu J, Yang XW, O'Dell TJ, Marvin JS, Ellisman MH, Bushong EA, Looger LL, Khakh BS. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. 82: 413-29. PMID 24742463 DOI: 10.1016/J.Neuron.2014.02.041 | 0.323 | |||
| 2013 | Wang N, Lu XH, Sandoval SV, Yang XW. An independent study of the preclinical efficacy of C2-8 in the R6/2 transgenic mouse model of Huntington's disease. Journal of Huntington's Disease. 2: 443-51. PMID 25062731 DOI: 10.3233/Jhd-130074 | 0.487 | |||
| 2012 | Lu XH, Yang XW. "Huntingtin holiday": progress toward an antisense therapy for Huntington's disease. Neuron. 74: 964-6. PMID 22726826 DOI: 10.1016/J.Neuron.2012.06.001 | 0.453 | |||
| 2012 | Cantle JP, Lu XH, Gu X, Yang XW. Cellular and molecular mechanisms implicated in pathogenesis of selective neurodegeneration in Huntington's disease Frontiers in Biology. 7: 459-476. DOI: 10.1007/S11515-012-1246-7 | 0.515 | |||
| 2011 | Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8306-19. PMID 21632951 DOI: 10.1523/Jneurosci.0567-11.2011 | 0.483 | |||
| 2011 | Yang XW, Lu XH. Molecular and cellular basis of obsessive-compulsive disorder-like behaviors: emerging view from mouse models. Current Opinion in Neurology. 24: 114-8. PMID 21386675 DOI: 10.1097/Wco.0B013E32834451Fb | 0.469 | |||
| 2009 | Lu XH. BAC to degeneration bacterial artificial chromosome (BAC)-mediated transgenesis for modeling basal ganglia neurodegenerative disorders. International Review of Neurobiology. 89: 37-56. PMID 19900614 DOI: 10.1016/S0074-7742(09)89002-8 | 0.424 | |||
| 2009 | Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1962-76. PMID 19228951 DOI: 10.1523/Jneurosci.5351-08.2009 | 0.55 | |||
| 2008 | Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6182-95. PMID 18550760 DOI: 10.1523/Jneurosci.0857-08.2008 | 0.555 | |||
| 2003 | Dwyer DS, Lu XH, Iii AM. Neuronal glucose metabolism and schizophrenia: therapeutic prospects? Expert Review of Neurotherapeutics. 3: 29-40. PMID 19810845 DOI: 10.1586/14737175.3.1.29 | 0.371 | |||
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