Robert J. Levy, M.D. - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Fishbein I, Alferiev IS, Adamo RF, Guerrero DT, Tang Y, Chorny M, Levy RJ. 174. Post-Deployment Modifications of Stent with Endothelial Cells Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32983-5  0.309
2009 Schoen FJ, Levy RJ. SnapShot: calcification of bioprosthetic heart valves. Biomaterials. 30: 4445-6. PMID 19623686 DOI: 10.1016/J.Biomaterials.2009.05.071  0.318
2003 Panyam J, Dali MM, Sahoo SK, Ma W, Chakravarthi SS, Amidon GL, Levy RJ, Labhasetwar V. Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 92: 173-87. PMID 14499195 DOI: 10.1016/S0168-3659(03)00328-6  0.408
2000 Desai MP, Hilfinger JM, Amidon GL, Levy RJ, Labhasetwar V. Immune response with biodegradable nanospheres and alum: Studies in rabbits using staphylococcal enterotoxin B-toxoid Journal of Microencapsulation. 17: 215-225. PMID 10738697 DOI: 10.1080/026520400288454  0.377
1999 Klugherz BD, Meneveau N, Chen W, Wade-Whittaker F, Papandreou G, Levy R, Wilensky RL. Sustained Intramural Retention and Regional Redistribution Following Local Vascular Delivery of Polylactic-Coglycolic Acid and Liposomal Nanoparticulate Formulations Containing Probucol. Journal of Cardiovascular Pharmacology and Therapeutics. 4: 167-174. PMID 10684538 DOI: 10.1177/107424849900400306  0.317
1998 Song C, Labhasetwar V, Cui X, Underwood T, Levy RJ. Arterial uptake of biodegradable nanoparticles for intravascular local drug delivery: Results with an acute dog model Journal of Controlled Release. 54: 201-211. PMID 9724907 DOI: 10.1016/S0168-3659(98)00016-9  0.318
1998 Labhasetwar V, Strickberger SA, Underwood T, Davis J, Levy RJ. Prevention of acute inducible atrial flutter in dogs by using an ibutilide-polymer-coated pacing electrode Journal of Cardiovascular Pharmacology. 31: 449-455. PMID 9514191 DOI: 10.1097/00005344-199803000-00017  0.387
1997 Desai MP, Labhasetwar V, Walter E, Levy RJ, Amidon GL. The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharmaceutical Research. 14: 1568-73. PMID 9434276 DOI: 10.1023/A:1012126301290  0.463
1997 Gott JP, Girardot MN, Girardot JM, Hall JD, Whitlark JD, Horsley WS, Dorsey LM, Levy RJ, Chen W, Schoen FJ, Guyton RA. Refinement of the alpha aminooleic acid bioprosthetic valve anticalcification technique. The Annals of Thoracic Surgery. 64: 50-8. PMID 9236334 DOI: 10.1016/S0003-4975(97)00118-5  0.331
1997 Chen W, Schoen FJ, Myers DJ, Levy RJ. Synergistic inhibition of calcification of porcine aortic root with preincubation in FeCl3 and alpha-amino oleic acid in a rat subdermal model. Journal of Biomedical Materials Research. 38: 43-8. PMID 9086416 DOI: 10.1002/(Sici)1097-4636(199721)38:1<43::Aid-Jbm6>3.0.Co;2-H  0.341
1997 Biedrzycki LM, Lerner E, Levy RJ, Schoen FJ. Differential calcification of cusps and aortic wall of failed stented porcine bioprosthetic valves Journal of Biomedical Materials Research. 34: 411-415. PMID 9054525 DOI: 10.1002/(Sici)1097-4636(19970315)34:4<411::Aid-Jbm2>3.0.Co;2-N  0.348
1997 Vyavahare N, Hirsch D, Lerner E, Baskin JZ, Schoen FJ, Bianco R, Kruth HS, Zand R, Levy RJ. Prevention of bioprosthetic heart valve calcification by ethanol preincubation: Efficacy and mechanisms Circulation. 95: 479-488. PMID 9008467 DOI: 10.1161/01.Cir.95.2.479  0.344
1997 Vyavahare NR, Chen W, Joshi RR, Lee CH, Hirsch D, Levy J, Schoen FJ, Levy RJ. Current progress in anticalcification for bioprosthetic and polymeric heart valves Cardiovascular Pathology. 6: 219-229. DOI: 10.1016/S1054-8807(97)00017-3  0.377
1997 Sintov A, Levy RJ. Polymeric drug delivery of enzymatically degradable pendant agents: Peptidyl-linked procainamide model system studies International Journal of Pharmaceutics. 146: 55-62. DOI: 10.1016/S0378-5173(96)04761-8  0.362
1997 Humphrey WR, Erickson LA, Simmons CA, Northrup JL, Wishka DG, Morris J, Labhasetwar V, Song C, Levy RJ, Shebuski RJ. The effect of intramural delivery of polymeric nanoparticles loaded with the antiproliferative 2-aminochromone U-86983 on neointimal hyperplasia development in balloon-injured porcine coronary arteries Advanced Drug Delivery Reviews. 24: 87-108. DOI: 10.1016/S0169-409X(96)00484-X  0.341
1997 Labhasetwar V, Song C, Levy RJ. Nanoparticle drug delivery system for restenosis Advanced Drug Delivery Reviews. 24: 63-85. DOI: 10.1016/S0169-409X(96)00483-8  0.304
1997 Song CX, Labhasetwar V, Levy RJ. Controlled release of U-86983 from double-layer biodegradable matrices: Effect of additives on release mechanism and kinetics Journal of Controlled Release. 45: 177-192. DOI: 10.1016/S0168-3659(96)01551-9  0.342
1997 Song CX, Labhasetwar V, Murphy H, Qu X, Humphrey WR, Shebuski RJ, Levy RJ. Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery Journal of Controlled Release. 43: 197-212. DOI: 10.1016/S0168-3659(96)01484-8  0.356
1996 Levy RJ, Labhasetwar VD, Strickberger SA, Underwood T, Davis J. Controlled release implant dosage forms for cardiac arrhythmias: Review and perspectives. Drug Delivery. 3: 137-142. PMID 26790908 DOI: 10.3109/10717549609029442  0.404
1996 Desai MP, Labhasetwar V, Amidon GL, Levy RJ. Gastrointestinal uptake of biodegradable microparticles: Effect of particle size Pharmaceutical Research. 13: 1838-1845. PMID 8987081 DOI: 10.1023/A:1016085108889  0.479
1996 Guzman LA, Labhasetwar V, Song C, Jang Y, Lincoff AM, Levy R, Topol EJ. Local intraluminal infusion of biodegradable polymeric nanoparticles: A novel approach for prolonged drug delivery after balloon angioplasty Circulation. 94: 1441-1448. PMID 8823004 DOI: 10.1161/01.Cir.94.6.1441  0.31
1996 Joshi RR, Underwood T, Frautschi JR, Phillips RE, Schoen FJ, Levy RJ. Calcification of polyurethanes implanted subdermally in rats is enhanced by calciphylaxis. Journal of Biomedical Materials Research. 31: 201-207. PMID 8731208 DOI: 10.1002/(Sici)1097-4636(199606)31:2<201::Aid-Jbm6>3.0.Co;2-R  0.334
1996 Muller DWM, Gordon D, Topol EJ, Levy RJ, Golomb G. Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting American Heart Journal. 131: 211-218. PMID 8579010 DOI: 10.1016/S0002-8703(96)90343-9  0.375
1995 Levy RJ, Qu X, Underwood T, Trachy J, Schoen FJ. Calcification of valved aortic allografts in rats: Effects of age, crosslinking, and inhibitors Journal of Biomedical Materials Research. 29: 217-226. PMID 7738069 DOI: 10.1002/Jbm.820290212  0.331
1995 Labhasetwar V, Underwood T, Schwendeman SP, Levy RJ. Iontophoresis for modulation of cardiac drug delivery in dogs Proceedings of the National Academy of Sciences of the United States of America. 92: 2612-2616. PMID 7708693 DOI: 10.1073/Pnas.92.7.2612  0.616
1995 Labhasetwar V, Levy RJ. Novel Delivery of Antiarrhythmic Agents Clinical Pharmacokinetics. 29: 1-5. PMID 7586894 DOI: 10.2165/00003088-199529010-00001  0.372
1995 Schwendeman SP, Labhasetwar V, Levy RJ. Model features of a cardiac iontophoretic drug delivery implant Pharmaceutical Research. 12: 790-795. PMID 7479570 DOI: 10.1023/A:1016288315617  0.59
1995 Levy RJ, Labhasetwar V, Song C, Lerner E, Chen W, Vyavahare N, Qu X. Polymeric drug delivery systems for treatment of cardiovascular calcification, arrhythmias and restenosis Journal of Controlled Release. 36: 137-147. DOI: 10.1016/0168-3659(95)00045-A  0.407
1994 Joshi RR, Frautschi JR, Phillips RE, Levy RJ. Phosphonated polyurethanes that resist calcification Journal of Applied Biomaterials. 5: 65-77. PMID 10146698 DOI: 10.1002/Jab.770050109  0.368
1994 Labhasetwar V, Underwood T, Gallagher M, Murphy G, Langberg J, Levy RJ. Sotalol controlled-release systems for arrhythmias: In vitro characterization, in vivo drug disposition, and electrophysiologic effects Journal of Pharmaceutical Sciences. 83: 156-164. PMID 8169781 DOI: 10.1002/Jps.2600830209  0.359
1994 Villa AE, Guzman LA, Chen W, Golomb G, Levy RJ, Topol EJ. Local delivery of dexamethasone for prevention of neointimal proliferation in a rat model of balloon angioplasty. Journal of Clinical Investigation. 93: 1243-1249. PMID 8132764 DOI: 10.1172/Jci117078  0.33
1994 Chen W, Schoen FJ, Levy RJ. Mechanism of efficacy of 2-amino oleic acid for inhibition of calcification of glutaraldehyde-pretreated porcine bioprosthetic heart valves Circulation. 90: 323-329. PMID 8026014 DOI: 10.1161/01.Cir.90.1.323  0.375
1994 Muller DWM, Golomb G, Gordon D, Levy RJ. Site-specific dexamethasone delivery for the prevention of neointimal thickening after vascular stent implantation Coronary Artery Disease. 5: 435-442. PMID 7921375 DOI: 10.1097/00019501-199405000-00010  0.379
1994 Schwendeman SP, Amidon GL, Labhasetwar V, Levy RJ. Modulated drug release using iontophoresis through heterogeneous cation- exchange membranes. 2. Influence of cation-exchanger content on membrane resistance and characteristic times Journal of Pharmaceutical Sciences. 83: 1482-1494. PMID 7884674 DOI: 10.1002/Jps.2600831023  0.639
1994 Chen W, Kim JD, Schoen FJ, Levy RJ. Effect of 2-amino oleic acid exposure conditions on the inhibition of calcification of glutaraldehyde cross-linked porcine aortic valves Journal of Biomedical Materials Research. 28: 1485-1495. PMID 7876288 DOI: 10.1002/Jbm.820281214  0.368
1994 Labhasetwar V, Underwood T, Heil RW, Gallagher M, Langberg J, Levy RJ. Epicardial administration of ibutilide from polyurethane matrices: Effects on defibrillation threshold and electrophysiologic parameters Journal of Cardiovascular Pharmacology. 24: 826-840. PMID 7532762 DOI: 10.1097/00005344-199424050-00019  0.392
1994 Schoen FJ, Hirsch D, Bianco RW, Levy RJ. Onset and progression of calcification in porcine aortic bioprosthetic valves Implanted as orthotopic mitral valve replacements in juvenile sheep The Journal of Thoracic and Cardiovascular Surgery. 108: 880-887. DOI: 10.1016/S0022-5223(94)70186-5  0.368
1993 Hirsch D, Drader J, Pathak YV, Yee R, Schoen FJ, Levy RJ. Synergistic inhibition of the calcification of glutaraldehyde pretreated bovine pericardium in a rat subdermal model by FeCl3 and ethanehydroxydiphosphonate: preincubation and polymeric controlled release studies. Biomaterials. 14: 705-11. PMID 8399967 DOI: 10.1016/0142-9612(93)90069-E  0.389
1993 Hirsch D, Drader J, Thomas TJ, Schoen FJ, Levy JT, Levy RJ. Inhibition of calcification of glutaraldehyde pretreated porcine aortic valve cusps with sodium dodecyl sulfate: Preincubation and controlled release studies Journal of Biomedical Materials Research. 27: 1477-1484. PMID 8113234 DOI: 10.1002/Jbm.820271203  0.365
1993 Schwendeman SP, Amidon GL, Levy RJ. Determinants of the modulated release of antiarrhythmic drugs by iontophoresis through polymer membranes Macromolecules. 26: 2264-2272. DOI: 10.1021/Ma00061A020  0.666
1993 Frautschi JR, Chinn JA, Phillips RE, Zhao Q, Anderson JM, Joshi R, Levy RJ. Degradation of polyurethanes in vitro and in vitro: comparison of different models Colloids and Surfaces B: Biointerfaces. 1: 305-313. DOI: 10.1016/0927-7765(93)80005-J  0.314
1993 Johnston TP, Webb CL, Schoen FJ, Levy RJ. Site-specific delivery of ethanehydroxy diphosphonate from refillable polyurethane reservoirs to inhibit bioprosthetic tissue calcification Journal of Controlled Release. 25: 227-240. DOI: 10.1016/0168-3659(93)90081-F  0.414
1993 Labhasetwar V, Kadish A, Underwood T, Sirinek M, Levy RJ. The efficacy of controlled release D-sotalol-polyurethane epicardial implants for ventricular arrhythmias due to acute ischemia in dogs Journal of Controlled Release. 23: 75-85. DOI: 10.1016/0168-3659(93)90072-D  0.358
1992 Schoen FJ, Levy RJ, Piehler HR. Pathological considerations in replacement cardiac valves. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 1: 29-52. PMID 25990036 DOI: 10.1016/1054-8807(92)90006-A  0.32
1992 Levy RJ, Schoen FJ, Anderson HC, Harasaki H, Koch TH, Brown W, Lian JB, Cumming R, Gavin JB. Cardiovascular implant calcification: a survey and update. Biomaterials. 12: 707-14. PMID 1799646 DOI: 10.1016/0142-9612(91)90017-5  0.389
1992 Schoen FJ, Levy RJ. Bioprosthetic heart valve calcification: membrane-mediated events and alkaline phosphatase Bone and Mineral. 17: 129-133. PMID 1611297 DOI: 10.1016/0169-6009(92)90723-Q  0.33
1992 Siden R, Flowers WE, Levy RJ. Epicardial propranolol administration for ventricular arrhythmias in dogs: matrix formulation and characterization Biomaterials. 13: 764-770. PMID 1391398 DOI: 10.1016/0142-9612(92)90015-G  0.393
1992 Schoen FJ, Levy RJ. Heart valve bioprostheses: Antimineralization European Journal of Cardio-Thoracic Surgery. 6: S91-S94. PMID 1389287 DOI: 10.1093/Ejcts/6.Supplement_1.S91  0.35
1992 Schwendeman SP, Amidon GL, Meyerhoff ME, Levy RJ. Modulated drug release using iontophoresis through heterogeneous cation exchange membranes: membrane preparation and influence of resin crosslinkage Macromolecules. 25: 2531-2540. DOI: 10.1021/Ma00035A036  0.638
1992 Bolling SF, Lin H, Ning X‐, Levy RJ. Local release polymeric-controlled immunotherapy of cardiac transplants in rats Polymers For Advanced Technologies. 3: 345-350. DOI: 10.1002/Pat.1992.220030610  0.335
1991 Labhasetwar V, Levy RJ. Implants for site-specific drug delivery Journal of Applied Biomaterials : An Official Journal of the Society For Biomaterials. 2: 211-212. PMID 10171143 DOI: 10.1002/Jab.770020309  0.344
1991 Levy RJ, Schoen FJ, Flowers WB, Staelin ST. Initiation of mineralization in bioprosthetic heart valves: studies of alkaline phosphatase activity and its inhibition by AlCl3 or FeCl3 preincubations. Journal of Biomedical Materials Research. 25: 905-35. PMID 1918108 DOI: 10.1002/Jbm.820250802  0.364
1990 Sintov A, Scott WA, Gallagher KP, Levy RJ. Conversion of ouabain-induced ventricular tachycardia in dogs with epicardial lidocaine: pharmacodynamics and functional effects. Pharmaceutical Research. 7: 28-33. PMID 2300532 DOI: 10.1023/A:1015875223446  0.374
1990 Pathak YV, Boyd J, Levy RJ, Schoen FJ. Prevention of calcification of glutaraldehyde pretreated bovine pericardium through controlled release polymeric implants: studies of Fe3+, Al3+, protamine sulphate and levamisole. Biomaterials. 11: 718-23. PMID 2128616 DOI: 10.1016/0142-9612(90)90034-N  0.393
1990 Sintov A, Scott WA, Siden R, Levy RJ. Efficacy of epicardial controlled-release lidocaine for ventricular tachycardia induced by rapid ventricular pacing in dogs. Journal of Cardiovascular Pharmacology. 16: 812-7. PMID 1703605 DOI: 10.1097/00005344-199011000-00018  0.35
1990 Johnston TP, Boyd JA, Ciesliga BL, Schoen FJ, Amidon G, Levy RJ. Controlled release of ethanehydroxy diphosphonate from polyurethane reservoirs to inhibit calcification of bovine pericardium used in bioprosthetic heart valves International Journal of Pharmaceutics. 59: 95-104. DOI: 10.1016/0378-5173(90)90083-G  0.536
1990 Levy RJ, Johnston TP, Sintov A, Golomb G. Controlled release implants for cardiovascular disease Journal of Controlled Release. 11: 245-254. DOI: 10.1016/0168-3659(90)90137-I  0.422
1989 Webb CL, Schoen FJ, Levy RJ. Covalent binding of aminopropanehydroxydiphosphonate to glutaraldehyde residues in pericardial bioprosthetic tissue: Stability and calcification inhibition studies Experimental and Molecular Pathology. 50: 291-302. PMID 2498121 DOI: 10.1016/0014-4800(89)90039-7  0.345
1989 Johnston TP, Bove EL, Bolling SF, Boyd JA, Ciesliga BL, Amidon GL, Schoen FJ, Levy RJ. Controlled release of 1-hydroxyethylidene diphosphonate: in vitro assessment and effects on bioprosthetic calcification in sheep tricuspid valve replacements International Journal of Pharmaceutics. 52: 139-148. DOI: 10.1016/0378-5173(89)90288-3  0.552
1988 Tsao JW, Schoen FJ, Shankar R, Sallis JD, Levy RJ. Retardation of calcification of bovine pericardium used in bioprosthetic heart valves by phosphocitrate and a synthetic analogue Biomaterials. 9: 393-397. PMID 3224124 DOI: 10.1016/0142-9612(88)90002-6  0.372
1988 Johnston TP, Schoen FJ, Levy RJ. Prevention of calcification of bioprosthetic heart valve leaflets by Ca2+ diphosphonate pretreatment Journal of Pharmaceutical Sciences. 77: 740-744. PMID 3147327 DOI: 10.1002/Jps.2600770903  0.38
1988 Webb CL, Benedict JJ, Schoen FJ, Linden JA, Levy RJ. Inhibition of bioprosthetic heart valve calcification with aminodiphosphonate covalently bound to residual aldehyde groups Annals of Thoracic Surgery. 46: 309-316. PMID 3137904 DOI: 10.1016/S0003-4975(10)65932-2  0.364
1988 Sintov A, Scott W, Dick M, Levy RJ. Cardiac controlled release for arrhythmia therapy: Lidocaine-polyurethane matrix studies Journal of Controlled Release. 8: 157-165. DOI: 10.1016/0168-3659(88)90042-9  0.411
1987 Golomb G, Dixon M, Smith MS, Schoen FJ, Levy RJ. Controlled-release drug delivery of diphosphonates to inhibit bioprosthetic heart valve calcification: Release rate modulation with silicone matrices via drug solubility and membrane coating Journal of Pharmaceutical Sciences. 76: 271-276. PMID 3110404 DOI: 10.1002/Jps.2600760402  0.419
1987 Webb CL, Benedict J, Linden J, Levy RJ. Inhibition Of Bioprosthetic (Bhv) Calcification (Call) With Covalently Bound Aminopropanehydroxydiphosphonate (Apd) Pediatric Research. 21: 196-196. DOI: 10.1203/00006450-198704010-00177  0.366
1986 Golomb G, Dixon M, Smith MS, Schoen FJ, Levy RJ. Inhibition of bioprosthetic heart valve calcification by sustained local delivery of Ca and Na diphosphonate via controlled release matrices Asaio Transactions / American Society For Artificial Internal Organs. 32: 587-590. PMID 3778777 DOI: 10.1097/00002480-198609000-00045  0.352
1986 Golomb G, Langer R, Schoen FJ, Smith MS, Choi YM, Levy RJ. Controlled release of diphosphonate to inhibit bioprosthetic heart valve calcification: dose-response and mechanistic studies Journal of Controlled Release. 4: 181-194. DOI: 10.1016/0168-3659(86)90002-7  0.434
1985 Levy RJ, Wolfrum J, Schoen FJ, Hawley MA, Lund SA, Langer R. Inhibition of calcification of bioprosthetic heart valves by local controlled-release diphosphonate Science. 228: 190-192. PMID 3919445 DOI: 10.1126/Science.3919445  0.495
1982 Fishbein MC, Levy RJ, Ferrans VJ, Dearden LC, Nashef A, Goodman AP, Carpentier A. Calcifications of cardiac valve bioprostheses. Biochemical, histologic, and ultrastructural observations in a subcutaneous implantation model system. The Journal of Thoracic and Cardiovascular Surgery. 83: 602-609. DOI: 10.1016/S0022-5223(19)37251-4  0.356
1980 Levy RJ, Zenker JA, Lian JB. Vitamin K-dependent calcium binding proteins in aortic valve calcification Journal of Clinical Investigation. 65: 563-566. PMID 7356695 DOI: 10.1172/Jci109700  0.3
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