| Year |
Citation |
Score |
| 2023 |
Saltarin F, Wegmüller A, Bejarano L, Ildiz ES, Zwicky P, Vianin A, Spadin F, Soukup K, Wischnewski V, Engelhardt B, Deutsch U, J Marques I, Frenz M, Joyce JA, Lyck R. Compromised Blood-Brain Barrier Junctions Enhance Melanoma Cell Intercalation and Extravasation. Cancers. 15. PMID 37894438 DOI: 10.3390/cancers15205071 |
0.35 |
|
| 2023 |
Johann L, Soldati S, Müller K, Lampe J, Marini F, Klein M, Schramm E, Ries N, Schelmbauer C, Palagi I, Karram K, Assmann JC, Khan MA, Wenzel J, Schmidt MH, ... ... Engelhardt B, et al. A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS. The Journal of Clinical Investigation. PMID 37856217 DOI: 10.1172/JCI168314 |
0.359 |
|
| 2023 |
Mapunda JA, Pareja J, Vladymyrov M, Bouillet E, Hélie P, Pleskač P, Barcos S, Andrae J, Vestweber D, McDonald DM, Betsholtz C, Deutsch U, Proulx ST, Engelhardt B. VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation. Nature Communications. 14: 5837. PMID 37730744 DOI: 10.1038/s41467-023-41580-4 |
0.321 |
|
| 2023 |
Matsuo K, Engelhardt B, Nishihara H. Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype. Journal of Visualized Experiments : Jove. PMID 37318257 DOI: 10.3791/65134 |
0.365 |
|
| 2023 |
Lazarevic I, Soldati S, Mapunda JA, Rudolph H, Rosito M, de Oliveira AC, Enzmann G, Nishihara H, Ishikawa H, Tenenbaum T, Schroten H, Engelhardt B. The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis. Fluids and Barriers of the Cns. 20: 39. PMID 37264368 DOI: 10.1186/s12987-023-00441-4 |
0.341 |
|
| 2023 |
Aydin S, Pareja J, Schallenberg VM, Klopstein A, Gruber T, Page N, Bouillet E, Blanchard N, Liblau R, Körbelin J, Schwaninger M, Johnson AJ, Schenk M, Deutsch U, Merkler D, ... Engelhardt B, et al. Antigen recognition detains CD8 T cells at the blood-brain barrier and contributes to its breakdown. Nature Communications. 14: 3106. PMID 37253744 DOI: 10.1038/s41467-023-38703-2 |
0.347 |
|
| 2023 |
Gonzalez-Fierro C, Fonte C, Dufourd E, Cazaentre V, Aydin S, Engelhardt B, Caspi RR, Xu B, Martin-Blondel G, Spicer JA, Trapani JA, Bauer J, Liblau RS, Bost C. Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell-Mediated Neuroinflammation. Neurology(R) Neuroimmunology & Neuroinflammation. 10. PMID 37080596 DOI: 10.1212/NXI.0000000000200117 |
0.369 |
|
| 2023 |
Li Z, Antila S, Nurmi H, Chilov D, Korhonen EA, Fang S, Karaman S, Engelhardt B, Alitalo K. Blockade of VEGFR3 signaling leads to functional impairment of dural lymphatic vessels without affecting autoimmune neuroinflammation. Science Immunology. 8: eabq0375. PMID 37058549 DOI: 10.1126/sciimmunol.abq0375 |
0.353 |
|
| 2022 |
Lyck R, Nishihara H, Aydin S, Soldati S, Engelhardt B. Modeling Brain Vasculature Immune Interactions In Vitro. Cold Spring Harbor Perspectives in Medicine. PMID 36617644 DOI: 10.1101/cshperspect.a041185 |
0.379 |
|
| 2022 |
Kemble AM, Hornsperger B, Ruf I, Richter H, Benz J, Kuhn B, Heer D, Wittwer M, Engelhardt B, Grether U, Collin L. A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature. Plos One. 17: e0268590. PMID 36084029 DOI: 10.1371/journal.pone.0268590 |
0.34 |
|
| 2022 |
Mapunda JA, Tibar H, Regragui W, Engelhardt B. How Does the Immune System Enter the Brain? Frontiers in Immunology. 13: 805657. PMID 35273596 DOI: 10.3389/fimmu.2022.805657 |
0.346 |
|
| 2022 |
Nishihara H, Perriot S, Gastfriend BD, Steinfort M, Cibien C, Soldati S, Matsuo K, Guimbal S, Mathias A, Palecek SP, Shusta EV, Du Pasquier R, Engelhardt B. Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis. Brain : a Journal of Neurology. PMID 35085379 DOI: 10.1093/brain/awac019 |
0.333 |
|
| 2021 |
Marchetti L, Francisco D, Soldati S, Jahromi NH, Barcos S, Gruber I, Pareja JR, Thiriot A, von Andrian U, Deutsch U, Lyck R, Bruggmann R, Engelhardt B. ACKR1 favors transcellular over paracellular T-cell diapedesis across the blood-brain barrier in neuroinflammation in vitro. European Journal of Immunology. PMID 34524684 DOI: 10.1002/eji.202149238 |
0.406 |
|
| 2021 |
Nishihara H, Gastfriend BD, Kasap P, Palecek SP, Shusta EV, Engelhardt B. Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions. Star Protocols. 2: 100563. PMID 34151293 DOI: 10.1016/j.xpro.2021.100563 |
0.34 |
|
| 2021 |
Castro Dias M, Odriozola Quesada A, Soldati S, Bösch F, Gruber I, Hildbrand T, Sönmez D, Khire T, Witz G, McGrath JL, Piontek J, Kondoh M, Deutsch U, Zuber B, Engelhardt B. Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood-brain barrier. Journal of Cell Science. 134. PMID 33912914 DOI: 10.1242/jcs.253880 |
0.393 |
|
| 2020 |
Nishihara H, Engelhardt B. Brain Barriers and Multiple Sclerosis: Novel Treatment Approaches from a Brain Barriers Perspective. Handbook of Experimental Pharmacology. PMID 33237504 DOI: 10.1007/164_2020_407 |
0.32 |
|
| 2020 |
Nishihara H, Gastfriend BD, Soldati S, Perriot S, Mathias A, Sano Y, Shimizu F, Gosselet F, Kanda T, Palecek SP, Du Pasquier R, Shusta EV, Engelhardt B. Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 33124083 DOI: 10.1096/fj.202001507RR |
0.372 |
|
| 2020 |
Locatelli G, Engelhardt B. Microglia Get a Little Help from "Th"-eir Friends. Immunity. 53: 484-486. PMID 32937150 DOI: 10.1016/J.Immuni.2020.08.011 |
0.407 |
|
| 2020 |
Marchetti L, Engelhardt B. Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation. Vascular Biology (Bristol, England). 2: H1-H18. PMID 32923970 DOI: 10.1530/VB-19-0033 |
0.367 |
|
| 2020 |
Stepanovska B, Zivkovic A, Enzmann G, Tietz S, Homann T, Kleuser B, Engelhardt B, Stark H, Huwiler A. Morpholino Analogues of Fingolimod as Novel and Selective S1P Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International Journal of Molecular Sciences. 21. PMID 32899717 DOI: 10.3390/Ijms21186463 |
0.382 |
|
| 2020 |
Heymans M, Figueiredo R, Dehouck L, Francisco D, Sano Y, Shimizu F, Kanda T, Bruggmann R, Engelhardt B, Winter P, Gosselet F, Culot M. Contribution of brain pericytes in blood-brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells. Fluids and Barriers of the Cns. 17: 48. PMID 32723387 DOI: 10.1186/S12987-020-00208-1 |
0.434 |
|
| 2020 |
Gericke C, Mallone A, Engelhardt B, Nitsch RM, Ferretti MT. Oligomeric Forms of Human Amyloid-Beta(1-42) Inhibit Antigen Presentation. Frontiers in Immunology. 11: 1029. PMID 32582162 DOI: 10.3389/Fimmu.2020.01029 |
0.34 |
|
| 2020 |
Bruggisser J, Tarek B, Wyder M, Müller P, von Ballmoos C, Witz G, Enzmann G, Deutsch U, Engelhardt B, Posthaus H. CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. Cell Host & Microbe. PMID 32497498 DOI: 10.1016/J.Chom.2020.05.003 |
0.379 |
|
| 2020 |
Li Z, Korhonen EA, Merlini A, Strauss J, Wihuri E, Nurmi H, Antila S, Paech J, Deutsch U, Engelhardt B, Chintharlapalli S, Koh GY, Flügel A, Alitalo K. Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS. The Journal of Clinical Investigation. PMID 32149735 DOI: 10.1172/Jci130308 |
0.44 |
|
| 2020 |
Nishihara H, Soldati S, Mossu A, Rosito M, Rudolph H, Muller WA, Latorre D, Sallusto F, Sospedra M, Martin R, Ishikawa H, Tenenbaum T, Schroten H, Gosselet F, Engelhardt B. Human CD4 T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro. Fluids and Barriers of the Cns. 17: 3. PMID 32008573 DOI: 10.1186/S12987-019-0165-2 |
0.491 |
|
| 2019 |
Haghayegh Jahromi N, Marchetti L, Moalli F, Duc D, Basso C, Tardent H, Kaba E, Deutsch U, Pot C, Sallusto F, Stein JV, Engelhardt B. Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 10: 3056. PMID 31993059 DOI: 10.3389/Fimmu.2019.03056 |
0.464 |
|
| 2019 |
Walter S, Gulbins E, Halmer R, Jahromi NH, Becker KA, Schottek A, Blatti C, Davies L, Schnoeder L, Bertsch T, Engelhardt B, Fassbender K. Pharmacological Inhibition of Acid Sphingomyelinase Ameliorates Experimental Autoimmune Encephalomyelitis. Neuro-Signals. 27: 20-31. PMID 31778303 DOI: 10.33594/000000183 |
0.315 |
|
| 2019 |
Wiatr M, Stump-Guthier C, Latorre D, Uhlig S, Weiss C, Ilonen J, Engelhardt B, Ishikawa H, Schwerk C, Schroten H, Tenenbaum T, Rudolph H. Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection. Journal of Neuroinflammation. 16: 232. PMID 31752904 DOI: 10.1186/S12974-019-1626-X |
0.447 |
|
| 2019 |
Castro Dias M, Mapunda JA, Vladymyrov M, Engelhardt B. Structure and Junctional Complexes of Endothelial, Epithelial and Glial Brain Barriers. International Journal of Molecular Sciences. 20. PMID 31671721 DOI: 10.3390/Ijms20215372 |
0.446 |
|
| 2019 |
Castro Dias M, Coisne C, Baden P, Enzmann G, Garrett L, Becker L, Hölter SM, Hrabě de Angelis M, Deutsch U, Engelhardt B. Claudin-12 is not required for blood-brain barrier tight junction function. Fluids and Barriers of the Cns. 16: 30. PMID 31511021 DOI: 10.1186/S12987-019-0150-9 |
0.437 |
|
| 2019 |
Garnier A, Laffont S, Garnier L, Kaba E, Deutsch U, Engelhardt B, Guéry JC. CD49d/CD29-integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation. European Journal of Immunology. PMID 31318439 DOI: 10.1002/Eji.201948086 |
0.405 |
|
| 2019 |
Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller WA, Lassmann H, Engelhardt B. PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation. Frontiers in Immunology. 10: 711. PMID 31024547 DOI: 10.3389/Fimmu.2019.00711 |
0.523 |
|
| 2019 |
Tietz SM, Engelhardt B. Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo. Journal of Visualized Experiments : Jove. PMID 30985749 DOI: 10.3791/59249 |
0.508 |
|
| 2019 |
Castro Dias M, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, ... ... Engelhardt B, et al. Claudin-3-deficient C57BL/6J mice display intact brain barriers. Scientific Reports. 9: 203. PMID 30659216 DOI: 10.1038/S41598-018-36731-3 |
0.431 |
|
| 2019 |
Mossu A, Rosito M, Khire T, Li Chung H, Nishihara H, Gruber I, Luke E, Dehouck L, Sallusto F, Gosselet F, McGrath JL, Engelhardt B. A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood-brain barrier under flow. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 39: 395-410. PMID 30565961 DOI: 10.1177/0271678X18820584 |
0.427 |
|
| 2019 |
Laffont S, Garnier A, Kaba E, Deutsch U, Engelhardt B, Guéry J. Author response for "CD49d/CD29‐integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation" European Journal of Immunology. DOI: 10.1002/Eji.201948086/V2/Response1 |
0.328 |
|
| 2018 |
Enzmann G, Kargaran S, Engelhardt B. Ischemia-reperfusion injury in stroke: impact of the brain barriers and brain immune privilege on neutrophil function. Therapeutic Advances in Neurological Disorders. 11: 1756286418794184. PMID 30181779 DOI: 10.1177/1756286418794184 |
0.389 |
|
| 2018 |
Tietz S, Périnat T, Greene G, Enzmann G, Deutsch U, Adams R, Imhof B, Aurrand-Lions M, Engelhardt B. Lack of Junctional Adhesion Molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis. Brain, Behavior, and Immunity. PMID 29920328 DOI: 10.1016/J.Bbi.2018.06.014 |
0.478 |
|
| 2018 |
Roth S, Singh V, Tiedt S, Schindler L, Huber G, Geerlof A, Antoine DJ, Anfray A, Orset C, Gauberti M, Fournier A, Holdt LM, Harris HE, Engelhardt B, Bianchi ME, et al. Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke. Science Translational Medicine. 10. PMID 29540615 DOI: 10.1126/Scitranslmed.Aao1313 |
0.531 |
|
| 2018 |
Enzmann GU, Pavlidou S, Vaas M, Klohs J, Engelhardt B. ICAM-1 C57BL/6 Mice Are Not Protected from Experimental Ischemic Stroke. Translational Stroke Research. 9: 608-621. PMID 29399739 DOI: 10.1007/S12975-018-0612-4 |
0.372 |
|
| 2018 |
Ghersi-Egea JF, Strazielle N, Catala M, Silva-Vargas V, Doetsch F, Engelhardt B. Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease. Acta Neuropathologica. PMID 29368213 DOI: 10.1007/S00401-018-1807-1 |
0.433 |
|
| 2017 |
Mathias A, Perriot S, Canales M, Blatti C, Gaubicher C, Schluep M, Engelhardt B, Du Pasquier R. Impaired T-cell migration to the CNS under fingolimod and dimethyl fumarate. Neurology(R) Neuroimmunology & Neuroinflammation. 4: e401. PMID 29075657 DOI: 10.1212/Nxi.0000000000000401 |
0.372 |
|
| 2017 |
Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, ... ... Engelhardt B, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology. 47: 1584-1797. PMID 29023707 DOI: 10.1002/Eji.201646632 |
0.347 |
|
| 2017 |
Zaretsky I, Atrakchi O, Mazor RD, Stoler-Barak L, Biram A, Feigelson SW, Gitlin AD, Engelhardt B, Shulman Z. ICAMs support B cell interactions with T follicular helper cells and promote clonal selection. The Journal of Experimental Medicine. 214: 3435-3448. PMID 28939548 DOI: 10.1084/Jem.20171129 |
0.356 |
|
| 2017 |
Llovera G, Benakis C, Enzmann G, Cai R, Arzberger T, Ghasemigharagoz A, Mao X, Malik R, Lazarevic I, Liebscher S, Ertürk A, Meissner L, Vivien D, Haffner C, Plesnila N, ... ... Engelhardt B, et al. The choroid plexus is a key cerebral invasion route for T cells after stroke. Acta Neuropathologica. PMID 28762187 DOI: 10.1007/S00401-017-1758-Y |
0.565 |
|
| 2017 |
Daneman R, Engelhardt B. "Brain Barriers in Health and Disease". Neurobiology of Disease. PMID 28552387 DOI: 10.1016/J.Nbd.2017.05.008 |
0.305 |
|
| 2017 |
Haghayegh Jahromi N, Tardent H, Enzmann G, Deutsch U, Kawakami N, Bittner S, Vestweber D, Zipp F, Stein JV, Engelhardt B. A Novel Cervical Spinal Cord Window Preparation Allows for Two-Photon Imaging of T-Cell Interactions with the Cervical Spinal Cord Microvasculature during Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 8: 406. PMID 28443093 DOI: 10.3389/Fimmu.2017.00406 |
0.333 |
|
| 2017 |
Engelhardt B, Vajkoczy P, Weller RO. The movers and shapers in immune privilege of the CNS. Nature Immunology. PMID 28092374 DOI: 10.1038/Ni.3666 |
0.42 |
|
| 2017 |
Lécuyer MA, Saint-Laurent O, Bourbonnière L, Larouche S, Larochelle C, Michel L, Charabati M, Abadier M, Zandee S, Haghayegh Jahromi N, Gowing E, Pittet C, Lyck R, Engelhardt B, Prat A. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28069965 DOI: 10.1073/Pnas.1614336114 |
0.496 |
|
| 2017 |
Małecki A, Skipor-Lahuta J, Toborek M, Abbott NJ, Antonetti DA, Su EJ, Lawrence DA, Atış M, Akcan U, Yılmaz CU, Orhan N, Düzgün P, Ceylan UD, Arıcan N, Karahüseyinoğlu S, ... ... Engelhardt B, et al. Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers Fluids and Barriers of the Cns. 14. DOI: 10.1186/S12987-017-0071-4 |
0.349 |
|
| 2016 |
Lyck R, Lécuyer MA, Abadier M, Wyss CB, Matti C, Rosito M, Enzmann G, Zeis T, Michel L, García Martín AB, Sallusto F, Gosselet F, Deutsch U, Weiner JA, Schaeren-Wiemers N, ... ... Engelhardt B, et al. ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X16678639. PMID 28273717 DOI: 10.1177/0271678X16678639 |
0.465 |
|
| 2016 |
Engelhardt B, Carare RO, Bechmann I, Flügel A, Laman JD, Weller RO. Vascular, glial, and lymphatic immune gateways of the central nervous system. Acta Neuropathologica. 132: 317-38. PMID 27522506 DOI: 10.1007/S00401-016-1606-5 |
0.407 |
|
| 2016 |
Atangana E, Schneider UC, Blecharz K, Magrini S, Wagner J, Nieminen-Kelhä M, Kremenetskaia I, Heppner FL, Engelhardt B, Vajkoczy P. Intravascular Inflammation Triggers Intracerebral Activated Microglia and Contributes to Secondary Brain Injury After Experimental Subarachnoid Hemorrhage (eSAH). Translational Stroke Research. PMID 27477569 DOI: 10.1007/S12975-016-0485-3 |
0.447 |
|
| 2016 |
Martin R, Sospedra M, Rosito M, Engelhardt B. Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis. European Journal of Immunology. PMID 27467894 DOI: 10.1002/Eji.201646485 |
0.331 |
|
| 2016 |
Rudolph H, Klopstein A, Gruber I, Blatti C, Lyck R, Engelhardt B. Post-arrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro. European Journal of Immunology. PMID 27338806 DOI: 10.1002/Eji.201546251 |
0.394 |
|
| 2016 |
Ferretti MT, Merlini M, Späni C, Gericke C, Schweizer N, Enzmann G, Engelhardt B, Kulic L, Suter T, Nitsch RM. T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis. Brain, Behavior, and Immunity. PMID 26872418 DOI: 10.1016/J.Bbi.2016.02.009 |
0.457 |
|
| 2016 |
Lazarevic I, Engelhardt B. Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier. Fluids and Barriers of the Cns. 13: 2. PMID 26833402 DOI: 10.1186/S12987-016-0027-0 |
0.449 |
|
| 2016 |
Petrovich E, Feigelson SW, Stoler-Barak L, Hatzav M, Solomon A, Bar-Shai A, Ilan N, Li JP, Engelhardt B, Vlodavsky I, Alon R. Lung ICAM-1 and ICAM-2 support spontaneous intravascular effector lymphocyte entrapment but are not required for neutrophil entrapment or emigration inside endotoxin-inflamed lungs. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26823454 DOI: 10.1096/Fj.201500046 |
0.321 |
|
| 2016 |
Imeri F, Schwalm S, Lyck R, Zivkovic A, Stark H, Engelhardt B, Pfeilschifter J, Huwiler A. Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology. PMID 26808312 DOI: 10.1016/J.Neuropharm.2016.01.031 |
0.447 |
|
| 2015 |
Lopes Pinheiro MA, Kooij G, Mizee MR, Kamermans A, Enzmann G, Lyck R, Schwaninger M, Engelhardt B, de Vries HE. Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke. Biochimica Et Biophysica Acta. PMID 26527183 DOI: 10.1016/J.Bbadis.2015.10.018 |
0.411 |
|
| 2015 |
Alonso A, Eisele P, Ebert AD, Griebe M, Engelhardt B, Szabo K, Hennerici MG, Gass A. Leptomeningeal contrast enhancement and blood-CSF barrier dysfunction in aseptic meningitis. Neurology® Neuroimmunology & Neuroinflammation. 2: e164. PMID 26516629 DOI: 10.1212/Nxi.0000000000000164 |
0.329 |
|
| 2015 |
Mundt S, Engelhardt B, Kirk CJ, Groettrup M, Basler M. Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV-induced meningitis. European Journal of Immunology. PMID 26464284 DOI: 10.1002/Eji.201545578 |
0.434 |
|
| 2015 |
Martin-Blondel G, Pignolet B, Tietz S, Yshii L, Gebauer C, Perinat T, Van Weddingen I, Blatti C, Engelhardt B, Liblau R. Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin. European Journal of Immunology. 45: 3302-12. PMID 26358409 DOI: 10.1002/Eji.201545632 |
0.421 |
|
| 2015 |
Wälchli T, Wacker A, Frei K, Regli L, Schwab ME, Hoerstrup SP, Gerhardt H, Engelhardt B. Wiring the Vascular Network with Neural Cues: A CNS Perspective. Neuron. 87: 271-96. PMID 26182414 DOI: 10.1016/J.Neuron.2015.06.038 |
0.363 |
|
| 2015 |
Tietz S, Engelhardt B. Brain barriers: Crosstalk between complex tight junctions and adherens junctions. The Journal of Cell Biology. 209: 493-506. PMID 26008742 DOI: 10.1083/Jcb.201412147 |
0.441 |
|
| 2015 |
Staat C, Coisne C, Dabrowski S, Stamatovic SM, Andjelkovic AV, Wolburg H, Engelhardt B, Blasig IE. Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. Biomaterials. 54: 9-20. PMID 25907035 DOI: 10.1016/J.Biomaterials.2015.03.007 |
0.35 |
|
| 2015 |
Eisele P, Griebe M, Szabo K, Wolf ME, Alonso A, Engelhardt B, Hennerici MG, Gass A. Investigation of leptomeningeal enhancement in MS: a postcontrast FLAIR MRI study. Neurology. 84: 770-5. PMID 25616480 DOI: 10.1212/Wnl.0000000000001286 |
0.337 |
|
| 2015 |
Joshi AU, Orset C, Engelhardt B, Baumgart-Vogt E, Gerriets T, Vivien D, Kanse SM. Deficiency of Factor VII activating protease alters the outcome of ischemic stroke in mice. The European Journal of Neuroscience. 41: 965-75. PMID 25615590 DOI: 10.1111/Ejn.12830 |
0.69 |
|
| 2015 |
Abadier M, Haghayegh Jahromi N, Cardoso Alves L, Boscacci R, Vestweber D, Barnum S, Deutsch U, Engelhardt B, Lyck R. Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier. European Journal of Immunology. 45: 1043-58. PMID 25545837 DOI: 10.1002/Eji.201445125 |
0.488 |
|
| 2014 |
Steiner E, Enzmann GU, Lyck R, Lin S, Rüegg MA, Kröger S, Engelhardt B. The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell and Tissue Research. 358: 465-79. PMID 25107608 DOI: 10.1007/S00441-014-1969-7 |
0.436 |
|
| 2014 |
Aubé B, Lévesque SA, Paré A, Chamma É, Kébir H, Gorina R, Lécuyer MA, Alvarez JI, De Koninck Y, Engelhardt B, Prat A, Côté D, Lacroix S. Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases Journal of Immunology. 193: 2438-2454. PMID 25049355 DOI: 10.4049/Jimmunol.1400401 |
0.441 |
|
| 2014 |
Cecchelli R, Aday S, Sevin E, Almeida C, Culot M, Dehouck L, Coisne C, Engelhardt B, Dehouck MP, Ferreira L. A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells. Plos One. 9: e99733. PMID 24936790 DOI: 10.1371/Journal.Pone.0099733 |
0.434 |
|
| 2014 |
Imeri F, Fallegger D, Zivkovic A, Schwalm S, Enzmann G, Blankenbach K, Meyer zu Heringdorf D, Homann T, Kleuser B, Pfeilschifter J, Engelhardt B, Stark H, Huwiler A. Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology. 85: 314-27. PMID 24863045 DOI: 10.1016/J.Neuropharm.2014.05.012 |
0.44 |
|
| 2014 |
Sathiyanadan K, Coisne C, Enzmann G, Deutsch U, Engelhardt B. PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE. European Journal of Immunology. 44: 2287-94. PMID 24740164 DOI: 10.1002/Eji.201344214 |
0.417 |
|
| 2014 |
Minten C, Alt C, Gentner M, Frei E, Deutsch U, Lyck R, Schaeren-Wiemers N, Rot A, Engelhardt B. DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation Brain. 137: 1454-1469. PMID 24625696 DOI: 10.1093/Brain/Awu045 |
0.456 |
|
| 2014 |
Engelhardt B, Liebner S. Novel insights into the development and maintenance of the blood-brain barrier. Cell and Tissue Research. 355: 687-99. PMID 24590145 DOI: 10.1007/S00441-014-1811-2 |
0.472 |
|
| 2014 |
Gorina R, Lyck R, Vestweber D, Engelhardt B. β2 integrin-mediated crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed blood-brain barrier. Journal of Immunology (Baltimore, Md. : 1950). 192: 324-37. PMID 24259506 DOI: 10.4049/Jimmunol.1300858 |
0.442 |
|
| 2014 |
Michel J, Tietz SM, Boscacci R, Blatti C, Lyck R, Charo IF, Ransohoff RM, Dejana E, Deutsch U, Engelhardt B. Involvement of junctional adhesion molecules in the pathogenesis of experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 275: 34. DOI: 10.1016/J.Jneuroim.2014.08.093 |
0.318 |
|
| 2014 |
Rudolph H, Blatti C, Schroten H, Lyck R, Engelhardt B. Identification of subset specific mechanisms for CD8+ versus CD4+ TEM cells mediating their migration across the inflamed blood–brain barrier under physiological flow in vitro Journal of Neuroimmunology. 275: 33. DOI: 10.1016/J.Jneuroim.2014.08.090 |
0.302 |
|
| 2014 |
Martin-blondel G, Pignolet B, Tietz S, Blatti C, Perinat T, Yshii L, Gebauer C, Engelhardt B, Liblau R. alpha4beta1 is a major molecular cue used by cytotoxic CD8 T cells to migrate into the CNS Journal of Neuroimmunology. 275: 31. DOI: 10.1016/J.Jneuroim.2014.08.085 |
0.361 |
|
| 2014 |
Jahromi NH, Boscacci R, Abadier M, Bullard DC, Barnum SR, Deutsch U, Lyck R, Engelhardt B. Defining the roles of ICAM-1 and ICAM-2 in the pathogenesis of experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 275: 29. DOI: 10.1016/J.Jneuroim.2014.08.079 |
0.313 |
|
| 2013 |
Engelhardt B. The brain barriers as therapeutic targets in neuroinflammation. Drug Research. 63. PMID 24242038 DOI: 10.1055/S-0033-1346705 |
0.336 |
|
| 2013 |
Moretti FA, Moser M, Lyck R, Abadier M, Ruppert R, Engelhardt B, Fässler R. Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 17005-10. PMID 24089451 DOI: 10.1073/Pnas.1316032110 |
0.452 |
|
| 2013 |
Paolinelli R, Corada M, Ferrarini L, Devraj K, Artus C, Czupalla CJ, Rudini N, Maddaluno L, Papa E, Engelhardt B, Couraud PO, Liebner S, Dejana E. Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro. Plos One. 8: e70233. PMID 23940549 DOI: 10.1371/Journal.Pone.0070233 |
0.444 |
|
| 2013 |
Coisne C, Lyck R, Engelhardt B. Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo. Fluids and Barriers of the Cns. 10: 7. PMID 23336847 DOI: 10.1186/2045-8118-10-7 |
0.487 |
|
| 2013 |
Enzmann G, Mysiorek C, Gorina R, Cheng YJ, Ghavampour S, Hannocks MJ, Prinz V, Dirnagl U, Endres M, Prinz M, Beschorner R, Harter PN, Mittelbronn M, Engelhardt B, Sorokin L. The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury. Acta Neuropathologica. 125: 395-412. PMID 23269317 DOI: 10.1007/S00401-012-1076-3 |
0.411 |
|
| 2013 |
Muldoon LL, Alvarez JI, Begley DJ, Boado RJ, Del Zoppo GJ, Doolittle ND, Engelhardt B, Hallenbeck JM, Lonser RR, Ohlfest JR, Prat A, Scarpa M, Smeyne RJ, Drewes LR, Neuwelt EA. Immunologic privilege in the central nervous system and the blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 13-21. PMID 23072749 DOI: 10.1038/Jcbfm.2012.153 |
0.431 |
|
| 2012 |
Wyss L, Schäfer J, Liebner S, Mittelbronn M, Deutsch U, Enzmann G, Adams RH, Aurrand-Lions M, Plate KH, Imhof BA, Engelhardt B. Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus. Plos One. 7: e45619. PMID 23029139 DOI: 10.1371/Journal.Pone.0045619 |
0.356 |
|
| 2012 |
Lyck R, Engelhardt B. Going against the tide--how encephalitogenic T cells breach the blood-brain barrier. Journal of Vascular Research. 49: 497-509. PMID 22948545 DOI: 10.1159/000341232 |
0.519 |
|
| 2012 |
Engelhardt B, Ransohoff RM. Capture, crawl, cross: the T cell code to breach the blood-brain barriers. Trends in Immunology. 33: 579-89. PMID 22926201 DOI: 10.1016/J.It.2012.07.004 |
0.489 |
|
| 2012 |
Ransohoff RM, Engelhardt B. The anatomical and cellular basis of immune surveillance in the central nervous system. Nature Reviews. Immunology. 12: 623-35. PMID 22903150 DOI: 10.1038/Nri3265 |
0.392 |
|
| 2012 |
Steiner E, Enzmann GU, Lin S, Ghavampour S, Hannocks MJ, Zuber B, Rüegg MA, Sorokin L, Engelhardt B. Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. Glia. 60: 1646-59. PMID 22782669 DOI: 10.1002/Glia.22383 |
0.355 |
|
| 2012 |
Sallusto F, Impellizzieri D, Basso C, Laroni A, Uccelli A, Lanzavecchia A, Engelhardt B. T-cell trafficking in the central nervous system. Immunological Reviews. 248: 216-27. PMID 22725964 DOI: 10.1111/J.1600-065X.2012.01140.X |
0.433 |
|
| 2012 |
Kronstein R, Seebach J, Grossklaus S, Minten C, Engelhardt B, Drab M, Liebner S, Arsenijevic Y, Taha AA, Afanasieva T, Schnittler HJ. Caveolin-1 opens endothelial cell junctions by targeting catenins. Cardiovascular Research. 93: 130-40. PMID 21960684 DOI: 10.1093/Cvr/Cvr256 |
0.413 |
|
| 2012 |
Engelhardt B. Molecular mechanisms of immune cell migration across the blood–brain barrier Vascular Pharmacology. 56: 332. DOI: 10.1016/J.Vph.2011.08.077 |
0.373 |
|
| 2011 |
Engelhardt B. Neuroscience. Blood-brain barrier differentiation. Science (New York, N.Y.). 334: 1652-3. PMID 22194564 DOI: 10.1126/Science.1216853 |
0.457 |
|
| 2011 |
Pfeiffer F, Schäfer J, Lyck R, Makrides V, Brunner S, Schaeren-Wiemers N, Deutsch U, Engelhardt B. Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis. Acta Neuropathologica. 122: 601-14. PMID 21983942 DOI: 10.1007/S00401-011-0883-2 |
0.469 |
|
| 2011 |
Lélu K, Laffont S, Delpy L, Paulet PE, Périnat T, Tschanz SA, Pelletier L, Engelhardt B, Guéry JC. Estrogen receptor α signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 187: 2386-93. PMID 21810607 DOI: 10.4049/Jimmunol.1101578 |
0.414 |
|
| 2011 |
Engelhardt B. β1-integrin/matrix interactions support blood-brain barrier integrity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1969-71. PMID 21772311 DOI: 10.1038/Jcbfm.2011.98 |
0.41 |
|
| 2011 |
Zattoni M, Mura ML, Deprez F, Schwendener RA, Engelhardt B, Frei K, Fritschy JM. Brain infiltration of leukocytes contributes to the pathophysiology of temporal lobe epilepsy Journal of Neuroscience. 31: 4037-4050. PMID 21411646 DOI: 10.1523/Jneurosci.6210-10.2011 |
0.397 |
|
| 2011 |
Engelhardt B, Coisne C. Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle. Fluids and Barriers of the Cns. 8: 4. PMID 21349152 DOI: 10.1186/2045-8118-8-4 |
0.426 |
|
| 2011 |
Döring A, Pfeiffer F, Meier M, Dehouck B, Tauber S, Deutsch U, Engelhardt B. TET inducible expression of the α4β7-integrin ligand MAdCAM-1 on the blood-brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis. European Journal of Immunology. 41: 813-21. PMID 21341265 DOI: 10.1002/Eji.201040912 |
0.499 |
|
| 2011 |
Coisne C, Engelhardt B. Tight junctions in brain barriers during central nervous system inflammation. Antioxidants & Redox Signaling. 15: 1285-303. PMID 21338320 DOI: 10.1089/Ars.2011.3929 |
0.455 |
|
| 2011 |
Bill R, Döring A, Deutsch U, Engelhardt B. PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice. Journal of Neuroimmunology. 232: 207-8. PMID 21051092 DOI: 10.1016/J.Jneuroim.2010.10.008 |
0.315 |
|
| 2011 |
Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B. Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain. Neuropathology and Applied Neurobiology. 37: 24-39. PMID 20946472 DOI: 10.1111/J.1365-2990.2010.01140.X |
0.492 |
|
| 2011 |
Steiner O, Coisne C, Engelhardt B, Lyck R. Comparison of immortalized bEnd5 and primary mouse brain microvascular endothelial cells as in vitro blood-brain barrier models for the study of T cell extravasation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 315-27. PMID 20606687 DOI: 10.1038/Jcbfm.2010.96 |
0.487 |
|
| 2010 |
Lélu K, Delpy L, Robert V, Foulon E, Laffont S, Pelletier L, Engelhardt B, Guéry JC. Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T-cell homing into the CNS. European Journal of Immunology. 40: 3489-98. PMID 21108469 DOI: 10.1002/Eji.201040678 |
0.409 |
|
| 2010 |
Steiner O, Coisne C, Cecchelli R, Boscacci R, Deutsch U, Engelhardt B, Lyck R. Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium. Journal of Immunology (Baltimore, Md. : 1950). 185: 4846-55. PMID 20861356 DOI: 10.4049/Jimmunol.0903732 |
0.472 |
|
| 2010 |
Jain P, Coisne C, Enzmann G, Rottapel R, Engelhardt B. Alpha4beta1 integrin mediates the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 7196-206. PMID 20483748 DOI: 10.4049/Jimmunol.0901404 |
0.415 |
|
| 2010 |
Boscacci RT, Pfeiffer F, Gollmer K, Sevilla AI, Martin AM, Soriano SF, Natale D, Henrickson S, von Andrian UH, Fukui Y, Mellado M, Deutsch U, Engelhardt B, Stein JV. Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. Blood. 116: 915-25. PMID 20395417 DOI: 10.1182/Blood-2009-11-254334 |
0.406 |
|
| 2010 |
Coisne C, Engelhardt B. Preclinical testing of strategies for therapeutic targeting of human T-cell trafficking in vivo. Methods in Molecular Biology (Clifton, N.J.). 616: 268-81. PMID 20379881 DOI: 10.1007/978-1-60761-461-6_17 |
0.434 |
|
| 2010 |
Engelhardt B. T cell migration into the central nervous system during health and disease: Different molecular keys allow access to different central nervous system compartments Clinical and Experimental Neuroimmunology. 1: 79-93. DOI: 10.1111/J.1759-1961.2010.009.X |
0.499 |
|
| 2009 |
Engelhardt B. PSGL-1--the hidden player in T cell trafficking into the brain in multiple sclerosis? Journal of Leukocyte Biology. 86: 1023-5. PMID 19875629 DOI: 10.1189/Jlb.0509358 |
0.5 |
|
| 2009 |
Engelhardt B, Sorokin L. The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction. Seminars in Immunopathology. 31: 497-511. PMID 19779720 DOI: 10.1007/S00281-009-0177-0 |
0.476 |
|
| 2009 |
Wolburg-Buchholz K, Mack AF, Steiner E, Pfeiffer F, Engelhardt B, Wolburg H. Loss of astrocyte polarity marks blood-brain barrier impairment during experimental autoimmune encephalomyelitis. Acta Neuropathologica. 118: 219-33. PMID 19533155 DOI: 10.1007/S00401-009-0558-4 |
0.37 |
|
| 2009 |
Lyck R, Ruderisch N, Moll AG, Steiner O, Cohen CD, Engelhardt B, Makrides V, Verrey F. Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1491-502. PMID 19491922 DOI: 10.1038/Jcbfm.2009.72 |
0.372 |
|
| 2009 |
Dodelet-Devillers A, Cayrol R, van Horssen J, Haqqani AS, de Vries HE, Engelhardt B, Greenwood J, Prat A. Functions of lipid raft membrane microdomains at the blood-brain barrier. Journal of Molecular Medicine (Berlin, Germany). 87: 765-74. PMID 19484210 DOI: 10.1007/S00109-009-0488-6 |
0.415 |
|
| 2009 |
Coisne C, Mao W, Engelhardt B. Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 182: 5909-13. PMID 19414741 DOI: 10.4049/Jimmunol.0803418 |
0.453 |
|
| 2009 |
Reboldi A, Coisne C, Baumjohann D, Benvenuto F, Bottinelli D, Lira S, Uccelli A, Lanzavecchia A, Engelhardt B, Sallusto F. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nature Immunology. 10: 514-23. PMID 19305396 DOI: 10.1038/Ni.1716 |
0.444 |
|
| 2009 |
Woodfin A, Voisin MB, Imhof BA, Dejana E, Engelhardt B, Nourshargh S. Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood. 113: 6246-57. PMID 19211506 DOI: 10.1182/Blood-2008-11-188375 |
0.367 |
|
| 2009 |
Bauer M, Brakebusch C, Coisne C, Sixt M, Wekerle H, Engelhardt B, Fässler R. Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 1920-5. PMID 19179279 DOI: 10.1073/Pnas.0808909106 |
0.357 |
|
| 2009 |
Kraus J, Oschmann P, Engelhardt B, Schiel C, Hornig C, Bauer R, Kern A, Traupe H, Dorndorf W. Soluble and cell surface ICAM-1 as markers for disease activity in multiple sclerosis Acta Neurologica Scandinavica. 98: 102-109. PMID 9724007 DOI: 10.1111/J.1600-0404.1998.Tb01727.X |
0.413 |
|
| 2008 |
Engelhardt B. Adhesion and Signalling Molecules Controlling the Extravasation of Leukocytes across the Endothelium. Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie. 35: 73-75. PMID 21512630 DOI: 10.1159/000119115 |
0.4 |
|
| 2008 |
Owens T, Bechmann I, Engelhardt B. Perivascular spaces and the two steps to neuroinflammation. Journal of Neuropathology and Experimental Neurology. 67: 1113-21. PMID 19018243 DOI: 10.1097/Nen.0B013E31818F9Ca8 |
0.445 |
|
| 2008 |
Nottebaum AF, Cagna G, Winderlich M, Gamp AC, Linnepe R, Polaschegg C, Filippova K, Lyck R, Engelhardt B, Kamenyeva O, Bixel MG, Butz S, Vestweber D. VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF. The Journal of Experimental Medicine. 205: 2929-45. PMID 19015309 DOI: 10.1084/Jem.20080406 |
0.39 |
|
| 2008 |
Linker RA, Lühder F, Kallen KJ, Lee DH, Engelhardt B, Rose-John S, Gold R. IL-6 transsignalling modulates the early effector phase of EAE and targets the blood-brain barrier. Journal of Neuroimmunology. 205: 64-72. PMID 18950871 DOI: 10.1016/J.Jneuroim.2008.09.007 |
0.35 |
|
| 2008 |
Schrage A, Wechsung K, Neumann K, Schumann M, Schulzke JD, Engelhardt B, Zeitz M, Hamann A, Klugewitz K. Enhanced T cell transmigration across the murine liver sinusoidal endothelium is mediated by transcytosis and surface presentation of chemokines. Hepatology (Baltimore, Md.). 48: 1262-72. PMID 18697212 DOI: 10.1002/Hep.22443 |
0.438 |
|
| 2008 |
Engelhardt B. The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Current Pharmaceutical Design. 14: 1555-65. PMID 18673197 DOI: 10.2174/138161208784705432 |
0.493 |
|
| 2008 |
Uboldi C, Döring A, Alt C, Estess P, Siegelman M, Engelhardt B. L-Selectin-deficient SJL and C57BL/6 mice are not resistant to experimental autoimmune encephalomyelitis European Journal of Immunology. 38: 2156-2167. PMID 18651702 DOI: 10.1002/Eji.200838209 |
0.347 |
|
| 2008 |
Pfeiffer F, Kumar V, Butz S, Vestweber D, Imhof BA, Stein JV, Engelhardt B. Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. European Journal of Immunology. 38: 2142-55. PMID 18629939 DOI: 10.1002/Eji.200838140 |
0.403 |
|
| 2008 |
Engelhardt B. Immune cell entry into the central nervous system: involvement of adhesion molecules and chemokines. Journal of the Neurological Sciences. 274: 23-6. PMID 18573502 DOI: 10.1016/J.Jns.2008.05.019 |
0.474 |
|
| 2008 |
Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U. Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular Diseases (Basel, Switzerland). 25: 268-78. PMID 18292653 DOI: 10.1159/000118039 |
0.521 |
|
| 2008 |
Deutsch U, Schlaeger TM, Dehouck B, Döring A, Tauber S, Risau W, Engelhardt B. Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice. Experimental Cell Research. 314: 1202-16. PMID 18272150 DOI: 10.1016/J.Yexcr.2007.12.026 |
0.354 |
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| 2008 |
Neuwelt E, Abbott NJ, Abrey L, Banks WA, Blakley B, Davis T, Engelhardt B, Grammas P, Nedergaard M, Nutt J, Pardridge W, Rosenberg GA, Smith Q, Drewes LR. Strategies to advance translational research into brain barriers. The Lancet. Neurology. 7: 84-96. PMID 18093565 DOI: 10.1016/S1474-4422(07)70326-5 |
0.374 |
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| 2008 |
Engelhardt B, Kappos L. Natalizumab: targeting alpha4-integrins in multiple sclerosis. Neurodegenerative Diseases. 5: 16-22. PMID 18075270 DOI: 10.1159/000109933 |
0.338 |
|
| 2008 |
Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U, Keezer MR, Yu AYX, et al. EUSI-ESO News Cerebrovascular Diseases. 25: 288-288. DOI: 10.1159/000122836 |
0.412 |
|
| 2008 |
Pfeiffer F, Kumar V, Butz S, Vestweber D, Imhof BA, Stein JV, Engelhardt B. Cover Picture: Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node – Eur. J. Immunol. 8/2008 European Journal of Immunology. 38. DOI: 10.1002/Eji.200890034 |
0.393 |
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| 2007 |
Coisne C, Lyck R, Engelhardt B. Therapeutic targeting of leukocyte trafficking across the blood-brain barrier. Inflammation & Allergy Drug Targets. 6: 210-22. PMID 18220956 DOI: 10.2174/187152807783334328 |
0.45 |
|
| 2007 |
Döring A, Wild M, Vestweber D, Deutsch U, Engelhardt B. E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 8470-9. PMID 18056394 DOI: 10.4049/Jimmunol.179.12.8470 |
0.41 |
|
| 2007 |
Klotz L, Diehl L, Dani I, Neumann H, Oppen Nv, Dolf A, Endl E, Klockgether T, Engelhardt B, Knolle P. Brain endothelial PPARγ controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro Journal of Neuroimmunology. 190: 34-43. PMID 17719655 DOI: 10.1016/J.Jneuroim.2007.07.017 |
0.491 |
|
| 2007 |
Klotz L, Diehl L, Dani I, Neumann H, Endl E, Klockgether T, Engelhardt B, Knolle P. Brain endothelial PPAR-gamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro Aktuelle Neurologie. 34. DOI: 10.1055/S-2007-987505 |
0.437 |
|
| 2006 |
Engelhardt B. Regulation of Immune Cell Entry into the Central Nervous System Results and Problems in Cell Differentiation. 43: 259-280. PMID 17068976 DOI: 10.1007/400_020 |
0.433 |
|
| 2006 |
Wethmar K, Helmus Y, Lühn K, Jones C, Laskowska A, Varga G, Grabbe S, Lyck R, Engelhardt B, Bixel MG, Butz S, Loser K, Beissert S, Ipe U, Vestweber D, et al. Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues. European Journal of Immunology. 36: 2781-94. PMID 16981228 DOI: 10.1002/Eji.200526311 |
0.306 |
|
| 2006 |
Hochmeister S, Grundtner R, Bauer J, Engelhardt B, Lyck R, Gordon G, Korosec T, Kutzelnigg A, Berger JJ, Bradl M, Bittner RE, Lassmann H. Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 65: 855-865. PMID 16957579 DOI: 10.1097/01.Jnen.0000235119.52311.16 |
0.472 |
|
| 2006 |
Meairs S, Wahlgren N, Dirnagl U, Lindvall O, Rothwell P, Baron JC, Hossmann K, Engelhardt B, Ferro J, McCulloch J, Kaste M, Endres M, Koistinaho J, Planas A, Vivien D, et al. Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovascular Diseases (Basel, Switzerland). 22: 75-82. PMID 16790993 DOI: 10.1159/000093098 |
0.451 |
|
| 2006 |
Engelhardt B. Molecular mechanisms involved in T cell migration across the blood-brain barrier. Journal of Neural Transmission. 113: 477-485. PMID 16550326 DOI: 10.1007/S00702-005-0409-Y |
0.45 |
|
| 2006 |
Walter S, Doering A, Letiembre M, Liu Y, Hao W, Diem R, Bernreuther C, Glatzel M, Engelhardt B, Fassbender K. The LPS receptor, CD14, in experimental autoimmune encephalomyelitis and multiple sclerosis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 17: 167-72. PMID 16543733 DOI: 10.1055/S-2006-953207 |
0.349 |
|
| 2006 |
Engelhardt B. Immune cell migration across the blood–brain barrier: molecular mechanisms and therapeutic targeting Future Neurology. 1: 47-56. DOI: 10.2217/14796708.1.1.47 |
0.455 |
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| 2005 |
Schulz M, Engelhardt B. The circumventricular organs participate in the immunopathogenesis of experimental autoimmune encephalomyelitis Cerebrospinal Fluid Research. 2: 8-8. PMID 16197544 DOI: 10.1186/1743-8454-2-8 |
0.487 |
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| 2005 |
Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, Engelhardt B, Cao G, DeLisser H, Schwartz MA. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 437: 426-31. PMID 16163360 DOI: 10.1038/Nature03952 |
0.375 |
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| 2005 |
Engelhardt B, Ransohoff RM. The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends in Immunology. 26: 485-495. PMID 16039904 DOI: 10.1016/J.It.2005.07.004 |
0.397 |
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| 2005 |
Engelhardt B, Kempe B, Merfeld-Clauss S, Laschinger M, Furie B, Wild MK, Vestweber D. P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 175: 1267-75. PMID 16002731 DOI: 10.4049/Jimmunol.175.2.1267 |
0.486 |
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| 2005 |
Semmrich M, Smith A, Feterowski C, Beer S, Engelhardt B, Busch DH, Bartsch B, Laschinger M, Hogg N, Pfeffer K, Holzmann B. Importance of integrin LFA-1 deactivation for the generation of immune responses Journal of Experimental Medicine. 201: 1987-1998. PMID 15955836 DOI: 10.1084/Jem.20041850 |
0.401 |
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| 2005 |
Schmidt K, Hoffend J, Altmann A, Strauss LG, Dimitrakopoulou-Strauss A, Engelhardt B, Koczan D, Peter J, Vorwald S, Eskerski H, Eisenhut M, Metz J, Kinscherf R, Haberkorn U. Transfer of the sFLT-1 Gene in Morris Hepatoma Results in Decreased Growth and Perfusion and Induction of Genes Associated with Stress Response Clinical Cancer Research. 11: 2132-2140. PMID 15788658 DOI: 10.1158/1078-0432.Ccr-04-2133 |
0.312 |
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| 2005 |
Alt C, Duvefelt K, Franzén B, Yang Y, Engelhardt B. Gene and protein expression profiling of the microvascular compartment in experimental autoimmune encephalomyelitis in C57BI/6 and SJL mice Brain Pathology. 15: 1-16. PMID 15779231 DOI: 10.1111/J.1750-3639.2005.Tb00094.X |
0.361 |
|
| 2005 |
Wolburg H, Wolburg-Buchholz K, Engelhardt B. Diapedesis of mononuclear cells across cerebral venules during experimental autoimmune encephalomyelitis leaves tight junctions intact Acta Neuropathologica. 109: 181-190. PMID 15549331 DOI: 10.1007/S00401-004-0928-X |
0.451 |
|
| 2005 |
Rothermel TA, Engelhardt B, Sheibani N. Polyoma virus middle-T-transformed PECAM-1 deficient mouse brain endothelial cells proliferate rapidly in culture and form hemangiomas in mice. Journal of Cellular Physiology. 202: 230-9. PMID 15389523 DOI: 10.1002/Jcp.20114 |
0.451 |
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| 2005 |
Klotz L, Diehl L, Engelhardt B, Knolle P, Klockgether T. Pioglitazone reduces the transmigratory capacity of activated T cells in an in-vitro model of the blood-brain-barrier Aktuelle Neurologie. 32: 577. DOI: 10.1055/S-2005-919608 |
0.44 |
|
| 2004 |
Chatzimanolis N, Kraus J, Bauer R, Engelhardt B, Bregenzer T, Kuehne BS, Tofighi J, Laske C, Stolz E, Blaes F, Voigt K, Traupe H, Kaps M, Oschmann P. CD45RA + ICAM-3+ lymphocytes in interferon-β1b-treated and -untreated patients with relapsing-remitting multiple sclerosis Acta Neurologica Scandinavica. 110: 377-385. PMID 15527450 DOI: 10.1111/J.1600-0404.2004.00346.X |
0.38 |
|
| 2004 |
Engelhardt B, Wolburg H. Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house? European Journal of Immunology. 34: 2955-2963. PMID 15376193 DOI: 10.1002/Eji.200425327 |
0.412 |
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| 2004 |
Kraus J, Ling AK, Hamm S, Voigt K, Oschmann P, Engelhardt B. Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro. Annals of Neurology. 56: 192-205. PMID 15293271 DOI: 10.1002/Ana.20161 |
0.426 |
|
| 2004 |
Bixel G, Kloep S, Butz S, Petri B, Engelhardt B, Vestweber D. Mouse CD99 participates in T-cell recruitment into inflamed skin. Blood. 104: 3205-13. PMID 15280198 DOI: 10.1182/Blood-2004-03-1184 |
0.363 |
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| 2004 |
Kraus J, Bauer R, Chatzimanolis N, Engelhardt B, Tofighi J, Bregenzer T, Kuehne BS, Stolz E, Blaes F, Morgen K, Traupe H, Kaps M, Oschmann P. Interferon-beta 1b leads to a short-term increase of soluble but long-term stabilisation of cell surface bound adhesion molecules in multiple sclerosis. Journal of Neurology. 251: 464-472. PMID 15083294 DOI: 10.1007/S00415-004-0358-7 |
0.379 |
|
| 2004 |
Hamm S, Dehouck B, Kraus J, Wolburg-Buchholz K, Wolburg H, Risau W, Cecchelli R, Engelhardt B, Dehouck MP. Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts. Cell and Tissue Research. 315: 157-66. PMID 14615934 DOI: 10.1007/S00441-003-0825-Y |
0.424 |
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| 2004 |
Voigt K, Kraus J, Oschmann P, Engelhardt B, Clauss M. Menadione inhibits attenuation of the paracellular permeability of a brain endothelioma cell monolayer by interferon-beta in vitro Aktuelle Neurologie. 31: 465. DOI: 10.1055/S-2004-833326 |
0.355 |
|
| 2003 |
Engelhardt B. Development of the blood-brain barrier. Cell and Tissue Research. 314: 119-129. PMID 12955493 DOI: 10.1007/S00441-003-0751-Z |
0.46 |
|
| 2003 |
Greenwood J, Amos CL, Walters CE, Couraud PO, Lyck R, Engelhardt B, Adamson P. Intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for T lymphocyte-mediated signaling and migration. Journal of Immunology (Baltimore, Md. : 1950). 171: 2099-108. PMID 12902516 DOI: 10.4049/Jimmunol.171.4.2099 |
0.408 |
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| 2003 |
Lyck R, Reiss Y, Gerwin N, Greenwood J, Adamson P, Engelhardt B. T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells Blood. 102: 3675-3683. PMID 12893765 DOI: 10.1182/Blood-2003-02-0358 |
0.475 |
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| 2003 |
Gratzinger D, Canosa S, Engelhardt B, Madri JA. Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1458-69. PMID 12890700 DOI: 10.1096/Fj.02-1040Com |
0.396 |
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| 2003 |
Franzén B, Duvefelt K, Jonsson C, Engelhardt B, Ottervald J, Wickman M, Yang Y, Schuppe-Koistinen I. Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-alpha. Molecular Brain Research. 115: 130-146. PMID 12877984 DOI: 10.1016/S0169-328X(03)00185-2 |
0.426 |
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| 2003 |
Rieckmann P, Engelhardt B. Building up the blood-brain barrier Nature Medicine. 9: 828-829. PMID 12835697 DOI: 10.1038/Nm0703-828 |
0.37 |
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| 2003 |
Vajkoczy P, Blum S, Lamparter M, Mailhammer R, Erber R, Engelhardt B, Vestweber D, Hatzopoulos AK. Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis. The Journal of Experimental Medicine. 197: 1755-65. PMID 12810693 DOI: 10.1084/Jem.20021659 |
0.389 |
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| 2003 |
Wolburg H, Wolburg-Buchholz K, Kraus J, Rascher-Eggstein G, Liebner S, Hamm S, Duffner F, Grote EH, Risau W, Engelhardt B. Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme. Acta Neuropathologica. 105: 586-92. PMID 12734665 DOI: 10.1007/S00401-003-0688-Z |
0.427 |
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| 2002 |
Laschinger M, Vajkoczy P, Engelhardt B. Encephalitogenic T cells use LFA-1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvessels in vivo. European Journal of Immunology. 32: 3598-3606. PMID 12516546 DOI: 10.1002/1521-4141(200212)32:12<3598::Aid-Immu3598>3.0.Co;2-6 |
0.375 |
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| 2002 |
Unger RE, Oltrogge JB, Briesen HV, Engelhardt B, Woelki U, Schlote W, Lorenz R, Bratzke H, Kirkpatrick CJ. Isolation and molecular characterization of brain microvascular endothelial cells from human brain tumors In Vitro Cellular & Developmental Biology – Animal. 38: 273-281. PMID 12418924 DOI: 10.1290/1071-2690(2002)038<0273:Iamcob>2.0.Co;2 |
0.438 |
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| 2002 |
Walter S, Fassbender K, Gulbins E, Liu Y, Rieschel M, Herten M, Bertsch T, Engelhardt B. Glycosylation processing inhibition by castanospermine prevents experimental autoimmune encephalomyelitis by interference with IL-2 receptor signal transduction. Journal of Neuroimmunology. 132: 1-10. PMID 12417427 DOI: 10.1016/S0165-5728(02)00308-9 |
0.348 |
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| 2002 |
Alt C, Laschinger M, Engelhardt B. Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis. European Journal of Immunology. 32: 2133-2144. PMID 12209625 DOI: 10.1002/1521-4141(200208)32:8<2133::Aid-Immu2133>3.0.Co;2-W |
0.5 |
|
| 2002 |
Kraus J, Kuehne BS, Tofighi J, Frielinghaus P, Stolz E, Blaes F, Laske C, Engelhardt B, Traupe H, Kaps M, Oschmann P. Serum cytokine levels do not correlate with disease activity and severity assessed by brain MRI in multiple sclerosis. Acta Neurologica Scandinavica. 105: 300-308. PMID 11939943 DOI: 10.1034/J.1600-0404.2002.1O199.X |
0.314 |
|
| 2002 |
Nasdala I, Wolburg-Buchholz K, Wolburg H, Kuhn A, Ebnet K, Brachtendorf G, Samulowitz U, Kuster B, Engelhardt B, Vestweber D, Butz S. A transmembrane tight junction protein selectively expressed on endothelial cells and platelets Journal of Biological Chemistry. 277: 16294-16303. PMID 11847224 DOI: 10.1074/Jbc.M111999200 |
0.387 |
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| 2002 |
Graesser D, Solowiej A, Bruckner M, Osterweil E, Juedes A, Davis S, Ruddle NH, Engelhardt B, Madri JA. Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. The Journal of Clinical Investigation. 109: 383-92. PMID 11827998 DOI: 10.1172/Jci13595 |
0.461 |
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| 2002 |
Kraus J, Engelhardt B, Chatzimanolis N, Bauer R, Tofighi J, Kuehne BS, Laske C, Stolz E, Frielinghaus P, Schaefer C, Blaes F, Traupe H, Kaps M, Oschmann P. Cell surface bound and soluble adhesion molecules in CSF and blood in multiple sclerosis: correlation with MRI-measures of subclinical disease severity and activity Journal of Neuroimmunology. 122: 175-185. PMID 11777557 DOI: 10.1016/S0165-5728(01)00469-6 |
0.368 |
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| 2001 |
Vajkoczy P, Laschinger M, Engelhardt B. α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels Journal of Clinical Investigation. 108: 557-565. PMID 11518729 DOI: 10.1172/Jci12440 |
0.425 |
|
| 2001 |
Westermann J, Engelhardt B, Hoffmann JC. Migration of T Cells in Vivo: Molecular Mechanisms and Clinical Implications Annals of Internal Medicine. 135: 279-295. PMID 11511143 DOI: 10.7326/0003-4819-135-4-200108210-00013 |
0.348 |
|
| 2001 |
Wolburg H, Wolburg-Buchholz K, Liebner S, Engelhardt B. Claudin-1, claudin-2 and claudin-11 are present in tight junctions of choroid plexus epithelium of the mouse. Neuroscience Letters. 307: 77-80. PMID 11427304 DOI: 10.1016/S0304-3940(01)01927-9 |
0.396 |
|
| 2001 |
Sixt M, Engelhardt B, Pausch F, Hallmann R, Wendler O, Sorokin LM. Endothelial Cell Laminin Isoforms, Laminins 8 and 10, Play Decisive Roles in T Cell Recruitment across the Blood–Brain Barrier in Experimental Autoimmune Encephalomyelitis Journal of Cell Biology. 153: 933-946. PMID 11381080 DOI: 10.1083/Jcb.153.5.933 |
0.443 |
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| 2001 |
Engelhardt B, Wolburg-Buchholz K, Wolburg H. Involvement of the choroid plexus in central nervous system inflammation. Microscopy Research and Technique. 52: 112-129. PMID 11135454 DOI: 10.1002/1097-0029(20010101)52:1<112::Aid-Jemt13>3.0.Co;2-5 |
0.498 |
|
| 2001 |
Kraus J, Engelhardt B, Kühne BS, Laske C, Stolz E, Traupe H, Kaps M, Oschmann P. Soluble and Cell Surface Bound Adhesion Molecules in Blood and Cerebrospinal Fluid as Diagnostic Markers and Parameters for Disease Activity, Disease Severity and Treatment Efficacy in Patients with Multiple Sclerosis. Lösliche und Zelloberflächen-gebundene Adhäsionsmoleküle in Blut und Liquor cerebrospinalis als diagnostische Marker und Parameter für Aktivität und Schwere der Erkrankung sowie Behandlungeffektivität bei Patienten mit Multipler Sklerose Laboratoriumsmedizin-Journal of Laboratory Medicine. 25: 548-556. DOI: 10.1515/Labm.2001.25.11-12.548 |
0.324 |
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| 2001 |
Hallmann R, Krause A, Laschinger M, Engelhardt B, Hynes R, Hammel M. SP0091 E-selectin deletion constructs allow the study of differential binding of mononuclear and polymorphonuclear leukocytes to e-selectin in inflammation Annals of the Rheumatic Diseases. 60. DOI: 10.1136/Annrheumdis-2001.37 |
0.374 |
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| 2000 |
Engelhardt B. Role of glucocorticoids on T cell recruitment across the blood-brain barrier. Zeitschrift Fur Rheumatologie. 59. PMID 11155798 DOI: 10.1007/S003930070012 |
0.519 |
|
| 2000 |
Kraus J, Oschmann P, Engelhardt B, Stolz E, Kuehne BS, Laske C, Schaefer C, Traupe H, Kaps M. CD45RA+ ICAM-3+ lymphocytesin cerebrospinal fluid and blood as markers of disease activity in patients with multiple sclerosis Acta Neurologica Scandinavica. 102: 326-332. PMID 11083511 DOI: 10.1034/J.1600-0404.2000.102005326.X |
0.372 |
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| 2000 |
Wong CW, Wiedle G, Ballestrem C, Wehrle-Haller B, Etteldorf S, Bruckner M, Engelhardt B, Gisler RH, Imhof BA. PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis. Molecular Biology of the Cell. 11: 3109-21. PMID 10982404 DOI: 10.1091/Mbc.11.9.3109 |
0.381 |
|
| 2000 |
Kraus J, Oschmann P, Engelhardt B, Bauer R, Schiel C, Kern A, Stolz E, Traupe A, Dorndorf W. Soluble and cell surface ICAM‐3 in blood and cerebrospinal fluid of patients with multiple sclerosis: influence of methylprednisolone treatment and relevance as markers for disease activity Acta Neurologica Scandinavica. 101: 135-139. PMID 10685862 DOI: 10.1034/J.1600-0404.2000.101002135.X |
0.381 |
|
| 2000 |
Laschinger M, Engelhardt B. Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro Journal of Neuroimmunology. 102: 32-43. PMID 10626664 DOI: 10.1016/S0165-5728(99)00156-3 |
0.446 |
|
| 1999 |
Reiss Y, Engelhardt B. T cell interaction with ICAM-1-deficient endothelium in vitro: transendothelial migration of different T cell populations is mediated by endothelial ICAM-1 and ICAM-2. International Immunology. 11: 1527-1539. PMID 10464174 DOI: 10.1093/Intimm/11.9.1527 |
0.427 |
|
| 1999 |
Boss B, Neeck G, Engelhardt B, Riedel W. Influence of corticosteroids on neutrophils, lymphocytes, their subsets, and T-cell activity markers in patients with active rheumatoid arthritis, compared to healthy controls Annals of the New York Academy of Sciences. 876: 198-200. PMID 10415610 DOI: 10.1111/J.1749-6632.1999.Tb07639.X |
0.332 |
|
| 1999 |
Wolburg K, Gerhardt H, Schulz M, Wolburg H, Engelhardt B. Ultrastructural localization of adhesion molecules in the healthy and inflamed choroid plexus of the mouse Cell and Tissue Research. 296: 259-269. PMID 10382270 DOI: 10.1007/S004410051287 |
0.437 |
|
| 1999 |
Gerwin N, Gonzalo JA, Lloyd C, Coyle AJ, Reiss Y, Banu N, Wang B, Xu H, Avraham H, Engelhardt B, Springer TA, Gutierrez-Ramos JC. Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness. Immunity. 10: 9-19. PMID 10023766 DOI: 10.1016/S1074-7613(00)80002-3 |
0.307 |
|
| 1998 |
Engelhardt B, Laschinger M, Schulz M, Samulowitz U, Vestweber D, Hoch G. The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin. Journal of Clinical Investigation. 102: 2096-2105. PMID 9854045 DOI: 10.1172/Jci4271 |
0.396 |
|
| 1998 |
Reiss Y, Hoch G, Deutsch U, Engelhardt B. T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells European Journal of Immunology. 28: 3086-3099. PMID 9808177 DOI: 10.1002/(Sici)1521-4141(199810)28:10<3086::Aid-Immu3086>3.0.Co;2-Z |
0.449 |
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| 1998 |
Kissel K, Hamm S, Schulz M, Vecchi A, Garlanda C, Engelhardt B. Immunohistochemical localization of the murine transferrin receptor (TfR) on blood-tissue barriers using a novel anti-TfR monoclonal antibody. Histochemistry and Cell Biology. 110: 63-72. PMID 9681691 DOI: 10.1007/S004180050266 |
0.361 |
|
| 1998 |
Engelhardt B, Martin-Simonet MT, Rott LS, Butcher EC, Michie SA. Adhesion molecule phenotype of T lymphocytes in inflamed CNS. Journal of Neuroimmunology. 84: 92-104. PMID 9600713 DOI: 10.1016/S0165-5728(97)00237-3 |
0.419 |
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| 1998 |
Engelhardt B, Schulz M, Samulowitz U, Vestweber J, Hoch G. α4β1 but not α4β7 is critically involved in the development of EAE in the SJL/J mouse: Evidence for a role in T cell migration and activation Journal of Neuroimmunology. 90: 21. DOI: 10.1016/S0165-5728(98)91302-9 |
0.41 |
|
| 1997 |
Röhnelt RK, Hoch G, Reiss Y, Engelhardt B. Immunosurveillance modelled in vitro: naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium. International Immunology. 9: 435-450. PMID 9088982 DOI: 10.1093/Intimm/9.3.435 |
0.4 |
|
| 1997 |
Engelhardt B, Vestweber D, Hallmann R, Schulz M. E- and P-Selectin Are Not Involved in the Recruitment of Inflammatory Cells Across the Blood-Brain Barrier in Experimental Autoimmune Encephalomyelitis Blood. 90: 4459-4472. DOI: 10.1182/Blood.V90.11.4459.4459_4459_4472 |
0.425 |
|
| 1996 |
Weller RO, Engelhardt B, Phillips MJ. Lymphocyte targeting of the central nervous system: a review of afferent and efferent CNS-immune pathways. Brain Pathology (Zurich, Switzerland). 6: 275-88. PMID 8864284 DOI: 10.1111/J.1750-3639.1996.Tb00855.X |
0.434 |
|
| 1995 |
Engelhardt B, Conley FK, Kilshaw PJ, Butcher EC. Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1. International Immunology. 7: 481-91. PMID 7540864 DOI: 10.1093/Intimm/7.3.481 |
0.391 |
|
| 1994 |
Engelhardt B, Görlach H, Risau W, Wekerle H. Lysis of rat brain microvascular endothelial cells mediated by resting but not activated MBP-specific CD4+ T cell lines. Journal of Neuroimmunology. 55: 69-80. PMID 7525644 DOI: 10.1016/0165-5728(94)90148-1 |
0.459 |
|
| 1994 |
Engelhardt B, Conley FK, Butcher EC. Cell adhesion molecules on vessels during inflammation in the mouse central nervous system. Journal of Neuroimmunology. 51: 199-208. PMID 7514186 DOI: 10.1016/0165-5728(94)90082-5 |
0.484 |
|
| 1992 |
Linington C, Engelhardt B, Kapocs G, Lassman H. Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody. Journal of Neuroimmunology. 40: 219-224. PMID 1385471 DOI: 10.1016/0165-5728(92)90136-9 |
0.373 |
|
| 1991 |
Wekerle H, Engelhardt B, Risau W, Meyermann R. Interaction of T lymphocytes with cerebral endothelial cells in vitro. Brain Pathology (Zurich, Switzerland). 1: 107-14. PMID 1727014 DOI: 10.1111/J.1750-3639.1991.Tb00647.X |
0.463 |
|
| 1990 |
Risau W, Engelhardt B, Wekerle H. Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro. The Journal of Cell Biology. 110: 1757-66. PMID 1692329 DOI: 10.1083/Jcb.110.5.1757 |
0.476 |
|
| 1989 |
Engelhardt B, Diamantstein T, Wekerle H. Immunotherapy of experimental autoimmune encephalomyelitis (EAE): differential effect of anti-IL-2 receptor antibody therapy on actively induced and T-line mediated EAE of the Lewis rat. Journal of Autoimmunity. 2: 61-73. PMID 2473763 DOI: 10.1016/0896-8411(89)90108-X |
0.328 |
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