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Silviu-Alin Bacanu - Publications

Affiliations: 
Virginia Commonwealth University School of Medicine, Richmond, VA 
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dahl A, Thompson M, An U, Krebs M, Appadurai V, Border R, Bacanu SA, Werge T, Flint J, Schork AJ, Sankararaman S, Kendler KS, Cai N. Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder. Nature Genetics. PMID 37985818 DOI: 10.1038/s41588-023-01559-9  0.329
2023 Ahangari M, Gentry AE, Hassan MF, Nguyen TH, Kendler KS, Bacanu SA, Peterson RE, Riley BP, Webb BT. Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information. Biorxiv : the Preprint Server For Biology. PMID 37745400 DOI: 10.1101/2023.09.11.557163  0.322
2023 Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JR, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, ... ... Bacanu SA, et al. Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. Medrxiv : the Preprint Server For Health Sciences. PMID 37693460 DOI: 10.1101/2023.08.31.23294915  0.755
2023 Gedik H, Peterson RE, Riley BP, Vladimirov VI, Bacanu SA. Integrative Post-Genome-Wide Association Study Analyses Relevant to Psychiatric Disorders: Imputing Transcriptome and Proteome Signals. Complex Psychiatry. 9: 130-144. PMID 37588130 DOI: 10.1159/000530223  0.43
2023 Gedik H, Nguyen TH, Peterson RE, Chatzinakos C, Vladimirov VI, Riley BP, Bacanu SA. Identifying potential risk genes and pathways for neuropsychiatric and substance use disorders using intermediate molecular mediator information. Frontiers in Genetics. 14: 1191264. PMID 37415601 DOI: 10.3389/fgene.2023.1191264  0.431
2022 Denham AN, Drake J, Gavrilov M, Taylor ZN, Bacanu SA, Vladimirov VI. Long Non-Coding RNAs: The New Frontier into Understanding the Etiology of Alcohol Use Disorder. Non-Coding Rna. 8. PMID 36005827 DOI: 10.3390/ncrna8040059  0.327
2022 Ahangari M, Everest E, Nguyen TH, Verrelli BC, Webb BT, Bacanu SA, Tahir Turanli E, Riley BP. Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects. Brain, Behavior, and Immunity. 104: 183-190. PMID 35714915 DOI: 10.1016/j.bbi.2022.06.007  0.343
2022 Sahajpal NS, Jill Lai CY, Hastie A, Mondal AK, Dehkordi SR, van der Made CI, Fedrigo O, Al-Ajli F, Jalnapurkar S, Byrska-Bishop M, Kanagal-Shamanna R, Levy B, Schieck M, Illig T, Bacanu SA, et al. Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. Iscience. 103760. PMID 35036860 DOI: 10.1016/j.isci.2022.103760  0.343
2021 Nguyen TH, He X, Brown RC, Webb BT, Kendler KS, Vladimirov VI, Riley BP, Bacanu SA. DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways. Briefings in Bioinformatics. PMID 33791774 DOI: 10.1093/bib/bbab067  0.364
2021 Chatzinakos C, Lee D, Cai N, Vladimirov VI, Webb BT, Riley BP, Flint J, Kendler KS, Ressler KJ, Daskalakis NP, Bacanu SA. Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 33576176 DOI: 10.1002/ajmg.b.32834  0.761
2020 Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, ... ... Bacanu SA, et al. A large-scale genome-wide association study meta-analysis of cannabis use disorder. The Lancet. Psychiatry. PMID 33096046 DOI: 10.1016/S2215-0366(20)30339-4  0.395
2020 Drake J, McMichael GO, Vornholt ES, Cresswell K, Williamson V, Chatzinakos C, Mamdani M, Hariharan S, Kendler KS, Kalsi G, Riley BP, Dozmorov M, Miles MF, Bacanu SA, Vladimirov VI. Assessing the Role of Long-Noncoding RNA in Nucleus Accumbens in Subjects with Alcohol Dependence. Alcoholism, Clinical and Experimental Research. PMID 33067813 DOI: 10.1111/acer.14479  0.665
2020 Chatzinakos C, Georgiadis F, Lee D, Cai N, Vladimirov VI, Docherty A, Webb BT, Riley BP, Flint J, Kendler KS, Daskalakis NP, Bacanu SA. TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32954640 DOI: 10.1002/Ajmg.B.32823  0.768
2020 Huckins LM, Chatzinakos C, Breen MS, Hartmann J, Klengel T, da Silva Almeida AC, Dobbyn A, Girdhar K, Hoffman GE, Klengel C, Logue MW, Lori A, Maihofer AX, Morrison FG, Nguyen HT, ... ... Bacanu SA, et al. Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts. Cell Reports. 31: 107716. PMID 32492425 DOI: 10.1016/J.Celrep.2020.107716  0.751
2020 Docherty AR, Shabalin AA, Adkins DE, Mann F, Krueger RF, Bacanu SA, Campbell A, Hayward C, Porteous DJ, McIntosh AM, Kendler KS. Molecular Genetic Risk for Psychosis Is Associated With Psychosis Risk Symptoms in a Population-Based UK Cohort: Findings From Generation Scotland. Schizophrenia Bulletin. PMID 32221549 DOI: 10.1093/Schbul/Sbaa042  0.331
2020 Sheerin CM, Lind MJ, Bountress KE, Marraccini ME, Amstadter AB, Bacanu SA, Nugent NR. Meta-analysis of Associations Between Hypothalamic-Pituitary-Adrenal Axis Genes and Risk of Posttraumatic Stress Disorder. Journal of Traumatic Stress. PMID 32216170 DOI: 10.1002/Jts.22484  0.5
2020 Polimanti R, Walters RK, Johnson EC, McClintick JN, Adkins AE, Adkins DE, Bacanu SA, Bierut LJ, Bigdeli TB, Brown S, Bucholz KK, Copeland WE, Costello EJ, Degenhardt L, Farrer LA, et al. Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. Molecular Psychiatry. PMID 32099098 DOI: 10.1038/S41380-020-0677-9  0.389
2020 Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, ... ... Bacanu SA, et al. Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology. e12880. PMID 32064741 DOI: 10.1111/Adb.12880  0.335
2020 Kendler KS, Chatzinakos C, Bacanu SA. The impact on estimations of genetic correlations by the use of super-normal, unscreened, and family-history screened controls in genome wide case-control studies. Genetic Epidemiology. PMID 31961015 DOI: 10.1002/Gepi.22281  0.718
2019 Hettema JM, Verhulst B, Chatzinakos C, Bacanu SA, Chen CY, Ursano RJ, Kessler RC, Gelernter J, Smoller JW, He F, Jain S, Stein MB. Genome-wide association study of shared liability to anxiety disorders in Army STARRS. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 31886626 DOI: 10.1002/Ajmg.B.32776  0.752
2019 Vornholt E, Mamdani M, McMichael GO, Drake J, Taylor ZN, Bacanu S, Vladimirov VI. M95. GENE NETWORK ANALYSIS REVEALS UNIQUE AND SHARED MODULES ASSOCIATED WITH ALCOHOL DEPENDENCE WITHIN THE PFC AND NAC European Neuropsychopharmacology. 29: S217. DOI: 10.1016/J.Euroneuro.2019.08.195  0.337
2019 Ahangari M, Gentry A, Kealhofer M, Sun C, Wormley B, Bacanu S, Webb BT, Kendler K, Riley B. S92Exome Variation In Ethanol Metabolizing Enzyme Genes In Irish Severe Alcohol Dependence (Ad) Cases European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.093  0.3
2018 Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, et al. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience. 21: 1656-1669. PMID 30482948 DOI: 10.1038/S41593-018-0275-1  0.365
2018 Reimers MA, Craver C, Dozmorov M, Bacanu SA, Kendler KS. The Coherence Problem: Finding Meaning in GWAS Complexity. Behavior Genetics. PMID 30446889 DOI: 10.1007/S10519-018-9935-X  0.502
2018 Hawn SE, Sheerin CM, Webb BT, Peterson RE, Do EK, Dick D, Kendler KS, Bacanu SA, Amstadter AB. Replication of the Interaction of PRKG1 and Trauma Exposure on Alcohol Misuse in an Independent African American Sample. Journal of Traumatic Stress. PMID 30376604 DOI: 10.1002/Jts.22339  0.414
2018 Edwards AC, Deak JD, Gizer IR, Lai D, Chatzinakos C, Wilhelmsen KP, Lindsay J, Heron J, Hickman M, Webb BT, Bacanu SA, Foroud TM, Kendler KS, Dick DM, Schuckit MA, et al. Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity. Alcoholism, Clinical and Experimental Research. PMID 30276832 DOI: 10.1111/Acer.13896  0.692
2018 Hawn SE, Sheerin CM, Lind MJ, Hicks TA, Marraccini ME, Bountress K, Bacanu SA, Nugent NR, Amstadter AB. GxE effects of FKBP5 and traumatic life events on PTSD: A meta-analysis. Journal of Affective Disorders. 243: 455-462. PMID 30273884 DOI: 10.1016/J.Jad.2018.09.058  0.437
2018 Bountress KE, Bacanu SA, Tomko RL, Korte KJ, Hicks T, Sheerin C, Lind MJ, Marraccini M, Nugent N, Amstadter AB. The Effects of a BDNF Val66Met Polymorphism on Posttraumatic Stress Disorder: A Meta-Analysis. Neuropsychobiology. 1-7. PMID 29874672 DOI: 10.1159/000489407  0.454
2018 Bacanu SA, Kendler KS. Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits. Genetic Epidemiology. PMID 29761553 DOI: 10.1002/Gepi.22125  0.33
2017 Chatzinakos C, Lee D, Webb BT, Vladimirov VI, Kendler KS, Bacanu SA. JEPEGMIX2: improved gene-level joint analysis of eQTLs in cosmopolitan cohorts. Bioinformatics (Oxford, England). PMID 28968763 DOI: 10.1093/Bioinformatics/Btx509  0.745
2017 Lind MJ, Marraccini ME, Sheerin CM, Bountress K, Bacanu SA, Amstadter AB, Nugent NR. Association of Posttraumatic Stress Disorder With rs2267735 in the ADCYAP1R1 Gene: A Meta-Analysis. Journal of Traumatic Stress. PMID 28746747 DOI: 10.1002/Jts.22211  0.421
2017 Peterson RE, Edwards AC, Bacanu SA, Dick DM, Kendler KS, Webb BT. The utility of empirically assigning ancestry groups in cross-population genetic studies of addiction. The American Journal On Addictions. PMID 28714599 DOI: 10.1111/Ajad.12586  0.426
2017 Bacanu SA. Sharing extended summary data from contemporary genetics studies is unlikely to threaten subject privacy. Plos One. 12: e0179504. PMID 28662067 DOI: 10.1371/Journal.Pone.0179504  0.323
2016 Peterson RE, Cai N, Bigdeli TB, Li Y, Reimers M, Nikulova A, Webb BT, Bacanu SA, Riley BP, Flint J, Kendler KS. The Genetic Architecture of Major Depressive Disorder in Han Chinese Women. Jama Psychiatry. PMID 28002544 DOI: 10.1001/Jamapsychiatry.2016.3578  0.316
2016 Bigdeli TB, Lee D, Webb BT, Riley BP, Vladimirov VI, Fanous AH, Kendler KS, Bacanu SA. A simple yet accurate correction for winner's curse can predict signals discovered in much larger genome scans. Bioinformatics (Oxford, England). PMID 27187203 DOI: 10.1093/Bioinformatics/Btw303  0.378
2016 Chen J, Bacanu SA, Yu H, Zhao Z, Jia P, Kendler KS, Kranzler HR, Gelernter J, Farrer L, Minica C, Pool R, Milaneschi Y, Boomsma DI, Penninx BW, Tyndale RF, et al. Genetic Relationship between Schizophrenia and Nicotine Dependence. Scientific Reports. 6: 25671. PMID 27164557 DOI: 10.1038/Srep25671  0.366
2015 Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, et al. Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 26663532 DOI: 10.1002/Ajmg.B.32402  0.346
2015 Lee D, Williamson VS, Bigdeli TB, Riley BP, Webb BT, Fanous AH, Kendler KS, Vladimirov VI, Bacanu SA. JEPEGMIX: gene-level joint analysis of functional SNPs in cosmopolitan cohorts. Bioinformatics (Oxford, England). PMID 26428293 DOI: 10.1093/Bioinformatics/Btv567  0.485
2015 Mamdani M, Williamson V, McMichael GO, Blevins T, Aliev F, Adkins A, Hack L, Bigdeli T, D van der Vaart A, Web BT, Bacanu SA, Kalsi G, Kendler KS, Miles MF, et al. Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence. Plos One. 10: e0137671. PMID 26381263 DOI: 10.1371/Journal.Pone.0137671  0.383
2015 Lee D, Bigdeli TB, Williamson VS, Vladimirov VI, Riley BP, Fanous AH, Bacanu SA. DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts. Bioinformatics (Oxford, England). PMID 26059716 DOI: 10.1093/Bioinformatics/Btv348  0.413
2015 Williamson VS, Mamdani M, McMichael GO, Kim AH, Lee D, Bacanu S, Vladimirov VI. Expression quantitative trait loci (eQTLs) in microRNA genes are enriched for schizophrenia and bipolar disorder association signals. Psychological Medicine. 1-13. PMID 25817407 DOI: 10.1017/S0033291715000483  0.381
2015 Lee D, Williamson VS, Bigdeli TB, Riley BP, Fanous AH, Vladimirov VI, Bacanu SA. JEPEG: a summary statistics based tool for gene-level joint testing of functional variants. Bioinformatics (Oxford, England). 31: 1176-82. PMID 25505091 DOI: 10.1093/Bioinformatics/Btu816  0.5
2015 Zhao Z, Xu J, Chen J, Kim S, Reimers M, Bacanu SA, Yu H, Liu C, Sun J, Wang Q, Jia P, Xu F, Zhang Y, Kendler KS, Peng Z, et al. Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder. Molecular Psychiatry. 20: 563-72. PMID 25113377 DOI: 10.1038/Mp.2014.82  0.512
2014 Aliev F, Latendresse SJ, Bacanu SA, Neale MC, Dick DM. Testing for measured gene-environment interaction: problems with the use of cross-product terms and a regression model reparameterization solution. Behavior Genetics. 44: 165-81. PMID 24531874 DOI: 10.1007/S10519-014-9642-1  0.303
2014 Bigdeli TB, Bacanu SA, Webb BT, Walsh D, O'Neill FA, Fanous AH, Riley BP, Kendler KS. Molecular validation of the schizophrenia spectrum. Schizophrenia Bulletin. 40: 60-5. PMID 23970557 DOI: 10.1093/Schbul/Sbt122  0.34
2013 Lee D, Bacanu SA. Association testing strategy for data from dense marker panels. Plos One. 8: e80540. PMID 24265830 DOI: 10.1371/Journal.Pone.0080540  0.358
2013 Bacanu SA, Chen X, Kendler KS. The genetic overlap between schizophrenia and height. Schizophrenia Research. 151: 226-8. PMID 24239283 DOI: 10.1016/J.Schres.2013.10.016  0.382
2013 Lee D, Bigdeli TB, Riley BP, Fanous AH, Bacanu SA. DIST: direct imputation of summary statistics for unmeasured SNPs. Bioinformatics (Oxford, England). 29: 2925-7. PMID 23990413 DOI: 10.1093/Bioinformatics/Btt500  0.402
2013 Bacanu SA, Kendler KS. Extracting actionable information from genome scans. Genetic Epidemiology. 37: 48-59. PMID 22996309 DOI: 10.1002/Gepi.21682  0.383
2012 Xu J, Sun J, Chen J, Wang L, Li A, Helm M, Dubovsky SL, Bacanu SA, Zhao Z, Chen X. RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia. Bmc Genomics. 13: S2. PMID 23282246 DOI: 10.1186/1471-2164-13-S8-S2  0.428
2012 Bacanu SA, Nelson MR, Whittaker JC. Comparison of statistical tests for association between rare variants and binary traits. Plos One. 7: e42530. PMID 22912707 DOI: 10.1371/journal.pone.0042530  0.364
2012 Bacanu SA. On optimal gene-based analysis of genome scans. Genetic Epidemiology. 36: 333-9. PMID 22508187 DOI: 10.1002/Gepi.21625  0.451
2011 Bacanu SA, Nelson MR, Whittaker JC. Comparison of methods and sampling designs to test for association between rare variants and quantitative traits. Genetic Epidemiology. 35: 226-35. PMID 21370253 DOI: 10.1002/gepi.20570  0.304
2005 McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, et al. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. American Journal of Human Genetics. 77: 582-95. PMID 16175504 DOI: 10.1086/491603  0.306
2004 Kaye WH, Devlin B, Barbarich N, Bulik CM, Thornton L, Bacanu SA, Fichter MM, Halmi KA, Kaplan AS, Strober M, Woodside DB, Bergen AW, Crow S, Mitchell J, Rotondo A, et al. Genetic analysis of bulimia nervosa: methods and sample description. The International Journal of Eating Disorders. 35: 556-70. PMID 15101071 DOI: 10.1002/Eat.10271  0.325
2002 Devlin B, Bacanu SA, Klump KL, Bulik CM, Fichter MM, Halmi KA, Kaplan AS, Strober M, Treasure J, Blake Woodside D, Berrettini WH, Kaye WH. Linkage analysis of anorexia nervosa incorporating behavioral covariates Human Molecular Genetics. 11: 689-696. PMID 11912184 DOI: 10.1093/Hmg/11.6.689  0.31
2002 Bacanu SA, Devlin B, Roeder K. Association studies for quantitative traits in structured populations. Genetic Epidemiology. 22: 78-93. PMID 11754475 DOI: 10.1002/Gepi.1045  0.363
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