Howard L Weiner, MD - Related publications

1985- Neurology Harvard Medical School - Brigham and Women's Hospital 
Multiple Sclerosis
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Donninelli G, Saraf-Sinik I, Mazziotti V, Capone A, Grasso MG, Battistini L, Reynolds R, Magliozzi R, Volpe E. Interleukin-9 regulates macrophage activation in the progressive multiple sclerosis brain. Journal of Neuroinflammation. 17: 149. PMID 32375811 DOI: 10.1186/s12974-020-01770-z   
2020 Tan M, Liu Y, Zhou R, Deng X, Li F, Liang K, Shi Y. Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China. Immunology. PMID 32460357 DOI: 10.1111/imm.13223   
2020 Gasser M, Lissner R, Nawalaniec K, Hsiao LL, Waaga-Gasser AM. KMP01D Demonstrates Beneficial Anti-inflammatory Effects on Immune Cells: An Preclinical Study of Patients With Colorectal Cancer. Frontiers in Immunology. 11: 684. PMID 32425932 DOI: 10.3389/fimmu.2020.00684   
2020 Devlin JC, Zwack EE, Tang MS, Li Z, Fenyo D, Torres VJ, Ruggles KV, Loke P. Distinct Features of Human Myeloid Cell Cytokine Response Profiles Identify Neutrophil Activation by Cytokines as a Prognostic Feature during Tuberculosis and Cancer. Journal of Immunology (Baltimore, Md. : 1950). PMID 32350082 DOI: 10.4049/jimmunol.1901133   
2020 Wen W, Su W, Tang H, Le W, Zhang X, Zheng Y, Liu X, Xie L, Li J, Ye J, Dong L, Cui X, Miao Y, Wang D, Dong J, et al. Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing. Cell Discovery. 6: 31. PMID 32377375 DOI: 10.1038/s41421-020-0168-9   
2020 Karlen H, Yousefi S, Simon HU, Simon D. IL-15 Expression Pattern in Atopic Dermatitis. International Archives of Allergy and Immunology. 1-5. PMID 32422638 DOI: 10.1159/000508515   
2020 Park HS, Back YW, Son YJ, Kim HJ. subsp MAP1889c Protein Induces Maturation of Dendritic Cells and Drives Th2-biased Immune Responses. Cells. 9. PMID 32290379 DOI: 10.3390/cells9040944   
2020 Manouchehri-Doulabi E, Abbaspour S, Rostami S, Faranoush M, Ghahramanfard F, Pak F, Barati M, Kokhaei P, Momtazi-Borojeni AA. Evaluating the mechanism underlying antitumor effect of interleukin 27 on B cells of chronic lymphocytic leukemia patients. Journal of Cellular Physiology. PMID 32383245 DOI: 10.1002/jcp.29747   
2020 Zhao Y, Qin L, Zhang P, Li K, Liang L, Sun J, Xu B, Dai Y, Li X, Zhang C, Peng Y, Feng Y, Li A, Hu Z, Xiang H, et al. Longitudinal COVID-19 profiling associates IL-1Ra and IL-10 with disease severity and RANTES with mild disease. Jci Insight. PMID 32501293 DOI: 10.1172/jci.insight.139834   
2020 Hewitson JP, West KA, James KR, Rani GF, Dey N, Romano A, Brown N, Teichmann SA, Kaye PM, Lagos D. Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32321759 DOI: 10.4049/jimmunol.1900940   
2020 Shohan M, Dehghani R, Khodadadi A, Dehnavi S, Ahmadi R, Joudaki N, Houshmandfar S, Shamshiri M, Shojapourian S, Bagheri N. Interleukin-22 and intestinal homeostasis: Protective or destructive? Iubmb Life. PMID 32365282 DOI: 10.1002/iub.2295   
2020 Tan AHJ, Vinanica N, Campana D. Chimeric antigen receptor-T cells with cytokine neutralizing capacity. Blood Advances. 4: 1419-1431. PMID 32271901 DOI: 10.1182/bloodadvances.2019001287   
2020 Prencipe R, Cirillo E, Giardino G, Gallo V, Menotta M, Magnani M, Barone MV, Palamaro L, Scalia G, Del Vecchio L, Pignata C. In Ataxia-Telangiectasia, Oral Betamethasone Administration Ameliorates Lymphocytes Functionality through Modulation of the IL-7/IL-7Rα Axis Paralleling the Neurological Behavior: A Comparative Report of Two Cases. Immunological Investigations. 1-9. PMID 32397775 DOI: 10.1080/08820139.2020.1761379   
2020 Kharwadkar R, Ulrich BJ, Abdul Qayum A, Koh B, Licona-Limón P, Flavell RA, Kaplan MH. Expression Efficiency of Multiple Reporter Alleles Is Determined by Cell Lineage. Immunohorizons. 4: 282-291. PMID 32439753 DOI: 10.4049/immunohorizons.1900082   
2020 Choy EH, De Benedetti F, Takeuchi T, Hashizume M, John MR, Kishimoto T. Translating IL-6 biology into effective treatments. Nature Reviews. Rheumatology. PMID 32327746 DOI: 10.1038/s41584-020-0419-z   
2020 Naik P, Singh S, Vishwakarma S, Kaur I, Dave VP, Kumar A, Joseph J. Multidrug-Resistant Evokes Differential Inflammatory Responses in Human Microglial and Retinal Pigment Epithelial Cells. Microorganisms. 8. PMID 32423093 DOI: 10.3390/microorganisms8050735   
2020 Cuinet J, Garbagnati A, Rusca M, Yerly P, Schneider AG, Kirsch M, Liaudet L. Cardiogenic shock elicits acute inflammation, delayed eosinophilia, and depletion of immune cells in most severe cases. Scientific Reports. 10: 7639. PMID 32377009 DOI: 10.1038/s41598-020-64702-0   
2020 Zhang H, Wang T, Han Z, Liu G. Mendelian randomization study to evaluate the effects of interleukin-6 signaling on four neurodegenerative diseases. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. PMID 32328834 DOI: 10.1007/s10072-020-04381-x   
2020 Chen Z, Hu Y, Gong Y, Zhang X, Cui L, Chen R, Yu Y, Yu Q, Chen Y, Diao H, Chen J, Wang Y, Shi Y. Interleukin-33 Alleviates Psoriatic Inflammation by Suppressing the Th17 Immune Response. Immunology. PMID 32306382 DOI: 10.1111/imm.13203   
2020 Martínez-Blanco M, Pérez-Rodríguez L, Lozano-Ojalvo D, Molina E, López-Fandiño R. Ovalbumin-Derived Peptides Activate Retinoic Acid Signalling Pathways and Induce Regulatory Responses Through Toll-Like Receptor Interactions. Nutrients. 12. PMID 32245005 DOI: 10.3390/nu12030831   
2020 Lu M, Tian X, Yang Z, Wang W, Tian AL, Li C, Yan R, Xu L, Song X, Li X. Proteomic analysis revealed T cell hyporesponsiveness induced by Haemonchus contortus excretory and secretory proteins. Veterinary Research. 51: 65. PMID 32404195 DOI: 10.1186/s13567-020-00790-0   
2020 Arnaldez FI, O'Day SJ, Drake CG, Fox BA, Fu B, Urba WJ, Montesarchio V, Weber JS, Wei H, Wigginton JM, Ascierto PA. The Society for Immunotherapy of Cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response. Journal For Immunotherapy of Cancer. 8. PMID 32385146 DOI: 10.1136/jitc-2020-000930   
2020 Han S, Chung DC, St Paul M, Liu ZQ, Garcia-Batres C, Elford AR, Tran CW, Chapatte L, Ohashi PS. Overproduction of IL-2 by Cbl-b deficient CD4 T cells provides resistance against regulatory T cells. Oncoimmunology. 9: 1737368. PMID 32313719 DOI: 10.1080/2162402X.2020.1737368   
2020 Li T, Zhang X, Lv Z, Gao L, Yan H. Increased Expression of Myeloid-Derived Suppressor Cells in Patients with HBV-Related Hepatocellular Carcinoma. Biomed Research International. 2020: 6527192. PMID 32258134 DOI: 10.1155/2020/6527192   
2020 Mizutani K, Shirakami E, Ichishi M, Matsushima Y, Umaoka A, Okada K, Yamaguchi Y, Watanabe M, Morita E, Yamanaka K. Systemic Dermatitis Model Mice Exhibit Atrophy of Visceral Adipose Tissue and Increase Stromal Cells via Skin-Derived Inflammatory Cytokines. International Journal of Molecular Sciences. 21. PMID 32397568 DOI: 10.3390/ijms21093367   
2020 Desbois AC, Cacoub P, Leroyer AS, Tellier E, Garrido M, Maciejewski-Duval A, Comarmond C, Barete S, Arock M, Bruneval P, Launay JM, Fouret P, Blank U, Rosenzwajg M, Klatzmann D, et al. Immunomodulatory role of Interleukin-33 in large vessel vasculitis. Scientific Reports. 10: 6405. PMID 32286393 DOI: 10.1038/s41598-020-63042-3   
2020 Fan NW, Dohlman TH, Foulsham W, McSoley M, Singh RB, Chen Y, Dana R. The role of Th17 immunity in chronic ocular surface disorders. The Ocular Surface. PMID 32470612 DOI: 10.1016/j.jtos.2020.05.009   
2020 Addeo A, Obeid M, Friedlaender A. COVID-19 and lung cancer: risks, mechanisms and treatment interactions. Journal For Immunotherapy of Cancer. 8. PMID 32434788 DOI: 10.1136/jitc-2020-000892   
2020 Lara PC, Burgos J, Macias D. Low dose lung radiotherapy for COVID-19 pneumonia. The rationale for a cost-effective anti-inflammatory treatment. Clinical and Translational Radiation Oncology. 23: 27-29. PMID 32373721 DOI: 10.1016/j.ctro.2020.04.006   
2020 Gabay C, Burmester GR, Strand V, Msihid J, Zilberstein M, Kimura T, van Hoogstraten H, Boklage SH, Sadeh J, Graham NMH, Boyapati A. Sarilumab and adalimumab differential effects on bone remodelling and cardiovascular risk biomarkers, and predictions of treatment outcomes. Arthritis Research & Therapy. 22: 70. PMID 32264972 DOI: 10.1186/s13075-020-02163-6   
2020 Salem S, Salem D, Gros P. Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases. Human Genetics. PMID 32232558 DOI: 10.1007/s00439-020-02154-2   
2020 Su C, Liu S, Ma X, Yang X, Liu J, Zheng P, Cao Y. Decitabine attenuates dextran sodium sulfate‑induced ulcerative colitis through regulation of immune regulatory cells and intestinal barrier. International Journal of Molecular Medicine. PMID 32468024 DOI: 10.3892/ijmm.2020.4605   
2020 Futami M, Suzuki K, Kato S, Ohmae S, Tahara Y, Nojima M, Imai Y, Mimura T, Watanabe Y, Tojo A. The novel multi-cytokine inhibitor TO-207 specifically inhibits pro-inflammatory cytokine secretion in monocytes without affecting the killing ability of CAR T cells. Plos One. 15: e0231896. PMID 32320454 DOI: 10.1371/journal.pone.0231896   
2020 Maier B, Leader AM, Chen ST, Tung N, Chang C, LeBerichel J, Chudnovskiy A, Maskey S, Walker L, Finnigan JP, Kirkling ME, Reizis B, Ghosh S, D'Amore NR, Bhardwaj N, et al. A conserved dendritic-cell regulatory program limits antitumour immunity. Nature. 580: 257-262. PMID 32269339 DOI: 10.1038/s41586-020-2134-y   
2020 Pinget GV, Tan J, Niewold P, Mazur E, Angelatos AS, King NJC, Macia L. Immune Modulation of Monocytes Dampens the IL-17 γδ T cell Response and Associated Psoriasis Pathology in Mice. The Journal of Investigative Dermatology. PMID 32389535 DOI: 10.1016/j.jid.2020.03.973   
2020 Keller HR, Kim HK, Jo Y, Gress RE, Hong C, Park JH. The Abundance and Availability of Cytokine Receptor IL-2Rβ (CD122) Constrain the Lymphopenia-Induced Homeostatic Proliferation of Naive CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32393513 DOI: 10.4049/jimmunol.1901276   
2020 Earl PL, Americo JL, Moss B. Natural killer cells expanded in vivo or ex vivo with IL-15 overcomes the inherent susceptibility of CAST mice to lethal infection with orthopoxviruses. Plos Pathogens. 16: e1008505. PMID 32320436 DOI: 10.1371/journal.ppat.1008505   
2020 Jo YG, Kim JC, Jin HM, Cho YN, Kee SJ, Park YW. Natural Killer T Cells Are Numerically and Functionally Deficient in Patients with Trauma. Journal of Innate Immunity. 1-11. PMID 32450553 DOI: 10.1159/000504324   
2020 DeKuiper JL, Cooperider HE, Lubben N, Ancel CM, Coussens PM. Subspecies Drives an Innate Th17-Like T Cell Response Regardless of the Presence of Antigen-Presenting Cells. Frontiers in Veterinary Science. 7: 108. PMID 32258066 DOI: 10.3389/fvets.2020.00108   
2020 Xing H, Tian G. Increased Interleukin-35 suppresses peripheral CD14 monocytes function in patients with Kawasaki disease. Bmc Immunology. 21: 17. PMID 32276581 DOI: 10.1186/s12865-020-00348-x   
2020 Xiong T, Attar M, Gnirck AC, Wunderlich M, Becker M, Rickassel C, Puelles VG, Meyer-Schwesinger C, Wiech T, Nies JF, Divivier M, Fuchs T, Schulze Zur Wiesch J, Taipaleenmäki H, Hoxha E, et al. Interleukin-9 protects from early podocyte injury and progressive glomerulosclerosis in Adriamycin-induced nephropathy. Kidney International. PMID 32446933 DOI: 10.1016/j.kint.2020.04.036   
2020 Hoving JC, Keeton R, Höft MA, Ozturk M, Otieno-Odhiambo P, Brombacher F. IL-4 Receptor-Alpha Signalling of Intestinal Epithelial Cells, Smooth Muscle Cells, and Macrophages Plays a Redundant Role in Oxazolone Colitis. Mediators of Inflammation. 2020: 4361043. PMID 32410852 DOI: 10.1155/2020/4361043   
2020 Zhang Y, Wang S, Song S, Yang X, Jin G. Ginsenoside Rg3 alleviates complete Freund's adjuvant - induced rheumatoid arthritis in mice by regulating CD4+CD25+Foxp3+ Treg cell. Journal of Agricultural and Food Chemistry. PMID 32275817 DOI: 10.1021/acs.jafc.0c01473   
2020 Bakheet SA, Alrwashied BS, Ansari MA, Nadeem A, Attia SM, Assiri MA, Alqahtani F, Ibrahim KE, Ahmad SF. CXCR3 antagonist AMG487 inhibits glucocorticoid-induced tumor necrosis factor-receptor-related protein and inflammatory mediators in CD45 expressing cells in collagen-induced arthritis mouse model. International Immunopharmacology. 84: 106494. PMID 32304993 DOI: 10.1016/j.intimp.2020.106494   
2020 Liu T, Zhang J, Yang Y, Ma H, Li Z, Zhang J, Cheng J, Zhang X, Zhao Y, Xia Z, Zhang L, Wu G, Yi J. The role of interleukin-6 in monitoring severe case of coronavirus disease 2019. Embo Molecular Medicine. PMID 32428990 DOI: 10.15252/emmm.202012421   
2020 Goelz N, Bosch AMS, Rand ML, Eekels JJM, Franzoso FD, Schmugge M. Increased levels of IL-10 and IL-1Ra counterbalance the proinflammatory cytokine pattern in acute pediatric immune thrombocytopenia. Cytokine. 130: 155078. PMID 32220726 DOI: 10.1016/j.cyto.2020.155078   
2020 Shin SH, Ye MK, Lee DW, Chae MH, Han BD. Nasal Epithelial Cells Activated with and House Dust Mite Induce Not Only Th2 but Also Th1 Immune Responses. International Journal of Molecular Sciences. 21. PMID 32294933 DOI: 10.3390/ijms21082693   
2020 Yu HW, Dong YY, Dang YH. [The modulatory activity of T cell immunoglobulin and mucin domain-containing protein 3 on T lymphocytes in patients with chronic heart failure]. Zhonghua Yi Xue Za Zhi. 100: 1315-1319. PMID 32375439 DOI: 10.3760/cma.j.cn112137-20190823-01876   
2020 Liu M, Chen HY, Luo L, Wang Y, Zhang D, Song N, Wang FB, Li Q, Zhang XL, Pan Q. Neutralization of IL-10 Produced by B Cells Promotes Protective Immunity during Persistent HCV Infection in Humanized Mice. European Journal of Immunology. PMID 32339264 DOI: 10.1002/eji.201948488   
2020 Costa MC, Paixão CS, Viana DL, Rocha BO, Saldanha M, da Mota LMH, Machado PRL, Pagliari C, de Oliveira MF, Arruda S, Carvalho EM, Carvalho LP. Mononuclear Phagocyte Activation Is Associated With the Immunopathology of Psoriasis. Frontiers in Immunology. 11: 478. PMID 32269570 DOI: 10.3389/fimmu.2020.00478