☰

Philip Cohen - Publications

Affiliations: 
Biochemistry University of Dundee, Dundee, Scotland, United Kingdom 
Area:
protein phosphorylation in cell regulation
Website:
http://www.ppu.mrc.ac.uk/research/?pid=1
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466 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Snelling T, Shpiro N, Gourlay R, Lamoliatte F, Cohen P. Coordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC. The Biochemical Journal. PMID 36098982 DOI: 10.1042/BCJ20220401  0.314
2021 Cohen P, Cross D, Jänne PA. Kinase drug discovery 20 years after imatinib: progress and future directions. Nature Reviews. Drug Discovery. PMID 34002056 DOI: 10.1038/s41573-021-00195-4  0.311
2021 Darling NJ, Cohen P. Nuts and bolts of the salt-inducible kinases (SIKs). The Biochemical Journal. 478: 1377-1397. PMID 33861845 DOI: 10.1042/BCJ20200502  0.426
2020 Hutchinson LD, Darling NJ, Nicolaou S, Gori I, Squair DR, Cohen P, Hill CS, Sapkota GP. Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses. Cell Death & Disease. 11: 49. PMID 31969556 DOI: 10.1038/S41419-020-2241-6  0.35
2019 Cohen P, Kelsall IR, Nanda SK, Zhang J. HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome. Advances in Biological Regulation. 100666. PMID 31615747 DOI: 10.1016/J.Jbior.2019.100666  0.355
2018 Nanda SK, Nagamori T, Windheim M, Amu S, Aviello G, Patterson-Kane J, Arthur JSC, Ley SC, Fallon P, Cohen P. ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism. Journal of Immunology (Baltimore, Md. : 1950). PMID 30355787 DOI: 10.4049/Jimmunol.1700614  0.318
2018 Thomas Y, Scott DC, Kristariyanto YA, Rinehart J, Clark K, Cohen P, Kurz T. The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation. Plos One. 13: e0199197. PMID 29958295 DOI: 10.1371/Journal.Pone.0199197  0.47
2017 Vollmer S, Strickson S, Zhang T, Gray N, Lee K, Rao V, Cohen P. The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and Toll-Like receptor agonists. The Biochemical Journal. PMID 28512203 DOI: 10.1042/Bcj20170097  0.394
2017 Zhang J, Macartney T, Peggie M, Cohen P. Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3. The Biochemical Journal. PMID 28507161 DOI: 10.1042/Bcj20170288  0.36
2017 Cohen P, Strickson S. The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways. Cell Death and Differentiation. PMID 28475177 DOI: 10.1038/Cdd.2017.17  0.407
2017 Bakshi S, Taylor J, Strickson S, Macartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon b. The Biochemical Journal. PMID 28159912 DOI: 10.1042/Bcj20160992  0.441
2016 Emmerich CH, Bakshi S, Kelsall IR, Ortiz-Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochemical and Biophysical Research Communications. PMID 27133719 DOI: 10.1016/J.Bbrc.2016.04.141  0.34
2015 Emmerich CH, Cohen P. Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting. Biochemical and Biophysical Research Communications. 466: 1-14. PMID 26325464 DOI: 10.1016/J.Bbrc.2015.08.109  0.309
2015 Malik N, Vollmer S, Nanda SK, Lopez-Pelaez M, Prescott A, Gray N, Cohen P. Suppression of Interferon β gene transcription by inhibitors of Bromodomain and Extra-Terminal (BET) family members. The Biochemical Journal. PMID 25891802 DOI: 10.1042/Bj20141523  0.333
2015 Akbar N, Nanda S, Belch J, Cohen P, Khan F. An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice. Arthritis Research & Therapy. 17: 22. PMID 25648164 DOI: 10.1186/S13075-015-0543-3  0.387
2015 Tiedje C, Lubas M, Tehrani M, Menon MB, Ronkina N, Rousseau S, Cohen P, Kotlyarov A, Gaestel M. p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex. Rna (New York, N.Y.). 21: 262-78. PMID 25525152 DOI: 10.1261/Rna.048090.114  0.31
2015 Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, ... Cohen P, et al. Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). Journal of Medicinal Chemistry. 58: 183-96. PMID 25075558 DOI: 10.1021/Jm500480K  0.481
2014 Lopez-Pelaez M, Lamont DJ, Peggie M, Shpiro N, Gray NS, Cohen P. Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 17432-7. PMID 25326418 DOI: 10.1073/Pnas.1418399111  0.466
2014 Zhang J, Clark K, Lawrence T, Peggie MW, Cohen P. An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation. The Biochemical Journal. 461: 531-7. PMID 24911653 DOI: 10.1042/Bj20140444  0.491
2014 Cohen P. Immune diseases caused by mutations in kinases and components of the ubiquitin system. Nature Immunology. 15: 521-9. PMID 24840983 DOI: 10.1038/Ni.2892  0.307
2014 Cohen P. The TLR and IL-1 signalling network at a glance. Journal of Cell Science. 127: 2383-90. PMID 24829146 DOI: 10.1242/Jcs.149831  0.317
2014 Shao WH, Cohen PL. The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets. Expert Review of Clinical Immunology. 10: 573-82. PMID 24678775 DOI: 10.1586/1744666X.2014.893827  0.305
2014 Lin KM, Hu W, Troutman TD, Jennings M, Brewer T, Li X, Nanda S, Cohen P, Thomas JA, Pasare C. IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 775-80. PMID 24379360 DOI: 10.1073/Pnas.1320294111  0.328
2013 Clark K, Nanda S, Cohen P. Molecular control of the NEMO family of ubiquitin-binding proteins. Nature Reviews. Molecular Cell Biology. 14: 673-85. PMID 23989959 DOI: 10.1038/Nrm3644  0.417
2013 Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, Komander D, Cohen P. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proceedings of the National Academy of Sciences of the United States of America. 110: 15247-52. PMID 23986494 DOI: 10.1073/Pnas.1314715110  0.308
2013 Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, ... ... Cohen P, et al. ABIN1 dysfunction as a genetic basis for lupus nephritis. Journal of the American Society of Nephrology : Jasn. 24: 1743-54. PMID 23970121 DOI: 10.1681/Asn.2013020148  0.312
2013 Ordureau A, Enesa K, Nanda S, Le Francois B, Peggie M, Prescott A, Albert PR, Cohen P. DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA. The Journal of Biological Chemistry. 288: 24569-80. PMID 23846693 DOI: 10.1074/Jbc.M113.479550  0.344
2013 Kilty I, Green MP, Bell AS, Brown DG, Dodd PG, Hewson C, Hughes SJ, Phillips C, Ryckmans T, Smith RT, van Hoorn WP, Cohen P, Jones LH. TAK1 inhibition in the DFG-out conformation. Chemical Biology & Drug Design. 82: 500-5. PMID 23745990 DOI: 10.1111/Cbdd.12169  0.404
2013 Krishnan N, Bencze G, Cohen P, Tonks NK. The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases. The Febs Journal. 280: 2830-41. PMID 23578302 DOI: 10.1111/Febs.12283  0.496
2013 Strickson S, Campbell DG, Emmerich CH, Knebel A, Plater L, Ritorto MS, Shpiro N, Cohen P. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. The Biochemical Journal. 451: 427-37. PMID 23441730 DOI: 10.1042/Bj20121651  0.355
2013 Cohen P, Alessi DR. Kinase drug discovery--what's next in the field? Acs Chemical Biology. 8: 96-104. PMID 23276252 DOI: 10.1021/Cb300610S  0.63
2013 Cohen P, Alessi DR. Correction to Kinase Drug Discovery – What’s Next in the Field? Acs Chemical Biology. 8: 464-464. DOI: 10.1021/Cb400055X  0.356
2012 McIver EG, Bryans J, Birchall K, Chugh J, Drake T, Lewis SJ, Osborne J, Smiljanic-Hurley E, Tsang W, Kamal A, Levy A, Newman M, Taylor D, Arthur JS, Clark K, ... Cohen P, et al. Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases. Bioorganic & Medicinal Chemistry Letters. 22: 7169-73. PMID 23099093 DOI: 10.1016/J.Bmcl.2012.09.063  0.33
2012 Clark K, MacKenzie KF, Petkevicius K, Kristariyanto Y, Zhang J, Choi HG, Peggie M, Plater L, Pedrioli PG, McIver E, Gray NS, Arthur JS, Cohen P. Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages. Proceedings of the National Academy of Sciences of the United States of America. 109: 16986-91. PMID 23033494 DOI: 10.1073/Pnas.1215450109  0.347
2012 Dzamko N, Inesta-Vaquera F, Zhang J, Xie C, Cai H, Arthur S, Tan L, Choi H, Gray N, Cohen P, Pedrioli P, Clark K, Alessi DR. The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling. Plos One. 7: e39132. PMID 22723946 DOI: 10.1371/Journal.Pone.0039132  0.717
2012 Pauls E, Shpiro N, Peggie M, Young ER, Sorcek RJ, Tan L, Choi HG, Cohen P. Essential role for IKKβ in production of type 1 interferons by plasmacytoid dendritic cells. The Journal of Biological Chemistry. 287: 19216-28. PMID 22511786 DOI: 10.1074/Jbc.M112.345405  0.309
2012 Goh ET, Arthur JS, Cheung PC, Akira S, Toth R, Cohen P. Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system. The Biochemical Journal. 441: 339-46. PMID 22007846 DOI: 10.1042/Bj20111415  0.508
2012 Clark K, MacKenzie K, Zhang J, Kristariyanto Y, Petkevicius K, Peggie M, Arthur S, Pedrioli P, Gray N, McIver E, Cohen P. P089 Identification of the first protein kinase inhibitors that switch macrophages from pro-inflammatory to anti-inflammatory cytokine production Cytokine. 59: 547-548. DOI: 10.1016/J.Cyto.2012.06.177  0.561
2011 Clark K, Takeuchi O, Akira S, Cohen P. The TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling Proceedings of the National Academy of Sciences of the United States of America. 108: 17093-17098. PMID 21949249 DOI: 10.1073/Pnas.1114194108  0.487
2011 Gleason CE, Ordureau A, Gourlay R, Arthur JS, Cohen P. Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β. The Journal of Biological Chemistry. 286: 35663-74. PMID 21862579 DOI: 10.1074/Jbc.M111.267567  0.438
2011 Nanda SK, Venigalla RK, Ordureau A, Patterson-Kane JC, Powell DW, Toth R, Arthur JS, Cohen P. Polyubiquitin binding to ABIN1 is required to prevent autoimmunity. The Journal of Experimental Medicine. 208: 1215-28. PMID 21606507 DOI: 10.1084/Jem.20102177  0.436
2011 Smith H, Liu XY, Dai L, Goh ET, Chan AT, Xi J, Seh CC, Qureshi IA, Lescar J, Ruedl C, Gourlay R, Morton S, Hough J, McIver EG, Cohen P, et al. The role of TBK1 and IKKε in the expression and activation of Pellino 1. The Biochemical Journal. 434: 537-48. PMID 21204785 DOI: 10.1042/Bj20101421  0.458
2011 Clark K, Peggie M, Plater L, Sorcek RJ, Young ER, Madwed JB, Hough J, McIver EG, Cohen P. Novel cross-talk within the IKK family controls innate immunity. The Biochemical Journal. 434: 93-104. PMID 21138416 DOI: 10.1042/Bj20101701  0.49
2010 Cohen P, Tcherpakov M. Will the ubiquitin system furnish as many drug targets as protein kinases? Cell. 143: 686-693. PMID 21111230 DOI: 10.1016/J.Cell.2010.11.016  0.373
2010 Akué-Gédu R, Nauton L, Théry V, Bain J, Cohen P, Anizon F, Moreau P. Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles Bioorganic and Medicinal Chemistry. 18: 6865-6873. PMID 20728368 DOI: 10.1016/J.Bmc.2010.07.036  0.403
2010 Cohen P. Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation Biochemical Journal. 425: 53-54. PMID 20001962 DOI: 10.1042/Bj20091428  0.433
2010 Cohen P, Frame S. Glycogen synthase kinase 3 Handbook of Cell Signaling, 2/E. 2: 569-573. DOI: 10.1016/B978-0-12-374145-5.00076-0  0.413
2009 Akué-Gédu R, Rossignol E, Azzaro S, Knapp S, Filippakopoulos P, Bullock AN, Bain J, Cohen P, Prudhomme M, Anizon F, Moreau P. Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors. Journal of Medicinal Chemistry. 52: 6369-81. PMID 19788246 DOI: 10.1021/Jm901018F  0.464
2009 Handoyo H, Stafford MJ, McManus E, Baltzis D, Peggie M, Cohen P. IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2. The Biochemical Journal. 424: 109-18. PMID 19754427 DOI: 10.1042/Bj20091271  0.426
2009 Cohen P. Keep nibbling at the edges Journal of Biological Chemistry. 284: 23891-23901. PMID 19515842 DOI: 10.1074/Jbc.X109.029835  0.32
2009 Cohen P. Profile of Philip Cohen. Interview by Carrie Arnold Proceedings of the National Academy of Sciences of the United States of America. 106: 7692-7694. PMID 19416871 DOI: 10.1073/Pnas.0903588106  0.486
2009 Clark K, Plater L, Peggie M, Cohen P. Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IκB Kinase ∈:A distinct upstream kinase mediates ser-172 phosphorylation and activation Journal of Biological Chemistry. 284: 14136-14146. PMID 19307177 DOI: 10.1074/Jbc.M109.000414  0.495
2009 Yang HT, Peggie M, Cohen P, Rousseau S. DAZAP1 interacts via its RNA-recognition motifs with the C-termini of other RNA-binding proteins Biochemical and Biophysical Research Communications. 380: 705-709. PMID 19285026 DOI: 10.1016/J.Bbrc.2009.01.166  0.339
2009 Smith H, Peggie M, Campbell DG, Vandermoere F, Carrick E, Cohen P. Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4 Proceedings of the National Academy of Sciences of the United States of America. 106: 4584-4590. PMID 19264966 DOI: 10.1073/Pnas.0900774106  0.438
2009 Cohen P. Targeting protein kinases for the development of anti-inflammatory drugs Current Opinion in Cell Biology. 21: 317-324. PMID 19217767 DOI: 10.1016/J.Ceb.2009.01.015  0.423
2009 Klevernic IV, Martin NMB, Cohen P. Regulation of the activity and expression of ERK8 by DNA damage Febs Letters. 583: 680-684. PMID 19166846 DOI: 10.1016/J.Febslet.2009.01.011  0.307
2009 Klevernic IV, Morton S, Davis RJ, Cohen P. Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage. The Biochemical Journal. 418: 625-34. PMID 19076070 DOI: 10.1042/Bj20082097  0.502
2008 Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. The ground state of embryonic stem cell self-renewal. Nature. 453: 519-23. PMID 18497825 DOI: 10.1038/Nature06968  0.509
2008 Cuomo ME, Knebel A, Morrice N, Paterson H, Cohen P, Mittnacht S. p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation Nature Cell Biology. 10: 723-730. PMID 18454140 DOI: 10.1038/Ncb1735  0.346
2008 Rousseau S, Papoutsopoulou M, Symons A, Cook D, Lucocq JM, Prescott AR, O'Garra A, Ley SC, Cohen P. TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. Journal of Cell Science. 121: 149-54. PMID 18187448 DOI: 10.1242/Jcs.018671  0.315
2008 Windheim M, Stafford M, Peggie M, Cohen P. Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase. Molecular and Cellular Biology. 28: 1783-91. PMID 18180283 DOI: 10.1128/Mcb.02380-06  0.318
2008 McCracken SR, Ramsay A, Heer R, Mathers ME, Jenkins BL, Edwards J, Robson CN, Marquez R, Cohen P, Leung HY. Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer. Oncogene. 27: 2978-88. PMID 18071319 DOI: 10.1038/Sj.Onc.1210963  0.354
2008 Mendoza H, Campbell DG, Burness K, Hastie J, Ronkina N, Shim JH, Arthur JS, Davis RJ, Gaestel M, Johnson GL, Ghosh S, Cohen P. Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex. The Biochemical Journal. 409: 711-22. PMID 18021073 DOI: 10.1042/Bj20071149  0.523
2008 Ordureau A, Smith H, Windheim M, Peggie M, Carrick E, Morrice N, Cohen P. The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1 Biochemical Journal. 409: 43-52. PMID 17997719 DOI: 10.1042/Bj20071365  0.43
2008 Windheim M, Lang C, Peggie M, Plater LA, Cohen P. Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide (Biochemical Journal (2007) 404 (179-190)) Biochemical Journal. 409: 789. DOI: 10.1042/Bj20061704  0.501
2007 Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P. The selectivity of protein kinase inhibitors: a further update. The Biochemical Journal. 408: 297-315. PMID 17850214 DOI: 10.1042/Bj20070797  0.674
2007 Inverarity IA, Viguier RFH, Cohen P, Hulme AN. Biotinylated anisomycin: A comparison of classical and "click" chemistry approaches Bioconjugate Chemistry. 18: 1593-1603. PMID 17705414 DOI: 10.1021/Bc070085U  0.308
2007 Cuadrado A, Lafarga V, Cheung PC, Dolado I, Llanos S, Cohen P, Nebreda AR. A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. The Embo Journal. 26: 2115-26. PMID 17380123 DOI: 10.1038/Sj.Emboj.7601657  0.303
2007 Windheim M, Lang C, Peggie M, Plater LA, Cohen P. Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. The Biochemical Journal. 404: 179-90. PMID 17348859 DOI: 10.1042/BJ20061704  0.357
2007 Sapkota GP, Cummings L, Newell FS, Armstrong C, Bain J, Frodin M, Grauert M, Hoffmann M, Schnapp G, Steegmaier M, Cohen P, Alessi DR. BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. The Biochemical Journal. 401: 29-38. PMID 17040210 DOI: 10.1042/Bj20061088  0.676
2007 Arbiser JL, Kau T, Konar M, Narra K, Ramchandran R, Summers SA, Vlahos CJ, Ye K, Perry BN, Matter W, Fischl A, Cook J, Silver PA, Bain J, Cohen P, et al. Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. Blood. 109: 560-5. PMID 16990598 DOI: 10.1182/Blood-2006-06-029934  0.471
2006 Hastie CJ, McLauchlan HJ, Cohen P. Assay of protein kinases using radiolabeled ATP: A protocol Nature Protocols. 1: 968-971. PMID 17406331 DOI: 10.1038/Nprot.2006.149  0.512
2006 Conner SH, Kular G, Peggie M, Shepherd S, Schüttelkopf AW, Cohen P, Van Aalten DMF. TAK1-binding protein 1 is a pseudophosphatase Biochemical Journal. 399: 427-434. PMID 16879102 DOI: 10.1042/Bj20061077  0.491
2006 Morton S, Yang HT, Moleleki N, Campbell DG, Cohen P, Rousseau S. Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ. The Biochemical Journal. 399: 265-73. PMID 16848763 DOI: 10.1042/Bj20060681  0.545
2006 Stafford MJ, Morrice NA, Peggie MW, Cohen P. Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62. Febs Letters. 580: 4010-4. PMID 16806191 DOI: 10.1016/J.Febslet.2006.06.004  0.512
2006 Rousseau S, Dolado I, Beardmore V, Shpiro N, Marquez R, Nebreda AR, Arthur JS, Case LM, Tessier-Lavigne M, Gaestel M, Cuenda A, Cohen P. CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway. Cellular Signalling. 18: 1897-905. PMID 16574378 DOI: 10.1016/J.Cellsig.2006.02.006  0.396
2006 Frobøse H, Rønn SG, Heding PE, Mendoza H, Cohen P, Mandrup-Poulsen T, Billestrup N. Suppressor of cytokine signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex Molecular Endocrinology. 20: 1587-1596. PMID 16543409 DOI: 10.1210/Me.2005-0301  0.377
2006 Klevernic IV, Stafford MJ, Morrice N, Peggie M, Morton S, Cohen P. Characterization of the reversible phosphorylation and activation of ERK8. The Biochemical Journal. 394: 365-73. PMID 16336213 DOI: 10.1042/Bj20051288  0.558
2006 Cohen P, Knebelt A. KESTREL: A powerful method for identifying the physiological substrates of protein kinases Biochemical Journal. 393: 1-6. PMID 16336195 DOI: 10.1042/Bj20051545  0.516
2005 Zhang M, Windheim M, Roe SM, Peggie M, Cohen P, Prodromou C, Pearl LH. Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. Molecular Cell. 20: 525-38. PMID 16307917 DOI: 10.1016/J.Molcel.2005.09.023  0.303
2005 Cuomo ME, Knebel A, Platt G, Morrice N, Cohen P, Mittnacht S. Regulation of microfilament organization by Kaposi sarcoma-associated herpes virus-cyclin·CDK6 phosphorylation of caldesmon Journal of Biological Chemistry. 280: 35844-35858. PMID 16115893 DOI: 10.1074/Jbc.M503877200  0.434
2005 Rousseau S, Peggie M, Campbell DG, Nebredaf AR, Cohen P. Nogo-B is a new physiological substrate for MAPKAP-K2 Biochemical Journal. 391: 433-440. PMID 16095439 DOI: 10.1042/Bj20050935  0.513
2005 Auld GC, Campbell DG, Morrice N, Cohen P. Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL Biochemical Journal. 389: 775-783. PMID 15910284 DOI: 10.1042/Bj20050733  0.57
2005 Cartlidge RA, Knebel A, Peggie M, Alexandrov A, Phizicky EM, Cohen P. The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. The Embo Journal. 24: 1696-705. PMID 15861136 DOI: 10.1038/Sj.Emboj.7600648  0.525
2005 Eyers CE, McNeill H, Knebel A, Morrice N, Arthur SJ, Cuenda A, Cohen P. The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ. The Biochemical Journal. 389: 127-35. PMID 15850461 DOI: 10.1042/Bj20050387  0.548
2005 Murray JT, Cummings LA, Bloomberg GB, Cohen P. Identification of different specificity requirements between SGK1 and PKBα Febs Letters. 579: 991-994. PMID 15710380 DOI: 10.1016/J.Febslet.2004.12.069  0.459
2005 Cohen PTW, Cohen P, Brustel YLM. Regulation of glycogen phosphorylase and glycogen synthase by adrenalin in soleus muscle of phosphorylase-kinase-deficient mice. Febs Journal. 115: 619-625. PMID 6786887 DOI: 10.1111/J.1432-1033.1981.Tb06247.X  0.45
2005 Rylatt DB, Aitken A, Bilham T, Condon GD, Embi N, Cohen P. Glycogen Synthase from Rabbit Skeletal Muscle Febs Journal. 107: 529-537. DOI: 10.1111/J.1432-1033.1980.Tb06060.X  0.51
2005 EMBI N, RYLATT DB, COHEN P. Glycogen Synthase Kinase-3 from Rabbit Skeletal Muscle European Journal of Biochemistry. 107: 519-527. DOI: 10.1042/Bst009241Pa  0.438
2005 Cohen P. Protein kinase inhibitors for the treatment of disease: The promise and the problems Handbook of Experimental Pharmacology. 167: 1-7. DOI: 10.1007/3-540-26670-4-1  0.324
2004 Murray JT, Campbell DG, Morrice N, Auld GC, Shpiro N, Marquez R, Peggie M, Bain J, Bloomberg GB, Grahammer F, Lang F, Wulff P, Kuhl D, Cohen P. Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. The Biochemical Journal. 384: 477-88. PMID 15461589 DOI: 10.1042/Bj20041057  0.537
2004 Murray JT, Campbell DG, Peggie M, Alfonso M, Cohen P. Identification of filamin C as a new physiological substrate of PKβα using KESTREL Biochemical Journal. 384: 489-494. PMID 15461588 DOI: 10.1042/Bj20041058  0.562
2004 McNeill H, Knebel A, Arthur JS, Cuenda A, Cohen P. A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs. The Biochemical Journal. 384: 391-400. PMID 15362974 DOI: 10.1042/Bj20041498  0.535
2004 Embark HM, Setiawan I, Poppendieck S, van de Graaf SF, Boehmer C, Palmada M, Wieder T, Gerstberger R, Cohen P, Yun CC, Bindels RJ, Lang F. Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 14: 203-12. PMID 15319523 DOI: 10.1159/000080329  0.302
2004 Morton S, Davis RJ, Cohen P. Signalling pathways involved in multisite phosphorylation of the transcription factor ATF-2. Febs Letters. 572: 177-83. PMID 15304344 DOI: 10.1016/J.Febslet.2004.07.031  0.511
2004 Yoshida H, Hastie CJ, McLauchlan H, Cohen P, Goedert M. Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK). Journal of Neurochemistry. 90: 352-8. PMID 15228592 DOI: 10.1111/J.1471-4159.2004.02479.X  0.476
2004 Cohen P, Goedert M. GSK3 inhibitors: development and therapeutic potential. Nature Reviews. Drug Discovery. 3: 479-87. PMID 15173837 DOI: 10.1038/Nrd1415  0.376
2004 Rosser EM, Morton S, Ashton KS, Cohen P, Hulme AN. Synthetic anisomycin analogues activating the JNK/SAPK1 and p38/SAPK2 pathways. Organic & Biomolecular Chemistry. 2: 142-9. PMID 14737674 DOI: 10.1039/B311242J  0.363
2004 Le Gallic L, Virgilio L, Cohen P, Biteau B, Mavrothalassitis G. ERF Nuclear Shuttling, a Continuous Monitor of Erk Activity That Liks It to Cell Cycle Progression Molecular and Cellular Biology. 24: 1206-1218. PMID 14729966 DOI: 10.1128/Mcb.24.3.1206-1218.2004  0.457
2004 Rena G, Bain J, Elliott M, Cohen P. D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a Embo Reports. 5: 60-65. PMID 14710188 DOI: 10.1038/Sj.Embor.7400048  0.512
2004 Boehmer C, Embark HM, Bauer A, Palmada M, Yun CH, Weinman EJ, Endou H, Cohen P, Lahme S, Bichler KH, Lang F. Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B Biochemical and Biophysical Research Communications. 313: 998-1003. PMID 14706641 DOI: 10.1016/J.Bbrc.2003.12.011  0.417
2004 Cheung PCF, Nebreda AR, Cohen P. TAB3, a new binding partner of the protein kinase TAK1 Biochemical Journal. 378: 27-34. PMID 14670075 DOI: 10.1042/Bj20031794  0.54
2004 Cole A, Frame S, Cohen P. Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event Biochemical Journal. 377: 249-255. PMID 14570592 DOI: 10.1042/Bj20031259  0.532
2003 Cohen P. The past and future of protein phosphatase research. Methods in Enzymology. 366. PMID 14674234 DOI: 10.1016/S0076-6879(03)66034-9  0.323
2003 Cheung PCF, Campbell DG, Nebreda AR, Cohen P. Feedback control of the protein kinase TAK1 by SAPK2a/p38α The Embo Journal. 22: 5793-5805. PMID 14592977 DOI: 10.1093/Emboj/Cdg552  0.463
2003 Caivano M, Rodriguez C, Cohen P, Alemany S. 15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. The Journal of Biological Chemistry. 278: 52124-30. PMID 14557273 DOI: 10.1074/jbc.M306583200  0.321
2003 Morton S, Davis RJ, McLaren A, Cohen P. A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun. The Embo Journal. 22: 3876-86. PMID 12881422 DOI: 10.1093/Emboj/Cdg388  0.501
2003 Boehmer C, Wilhelm V, Palmada M, Wallisch S, Henke G, Brinkmeier H, Cohen P, Pieske B, Lang F. Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A Cardiovascular Research. 57: 1079-1084. PMID 12650886 DOI: 10.1016/S0008-6363(02)00837-4  0.429
2003 Friedrich B, Feng Y, Cohen P, Risler T, Vandewalle A, Bröer S, Wang J, Pearce D, Lang F. The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC. Pflã¼Gers Archiv : European Journal of Physiology. 445: 693-6. PMID 12632189 DOI: 10.1007/S00424-002-0993-8  0.452
2003 Mody N, Campbell DG, Morrice N, Peggie M, Cohen P. An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro. The Biochemical Journal. 372: 567-75. PMID 12628002 DOI: 10.1042/Bj20030193  0.56
2003 Bain J, McLauchlan H, Elliott M, Cohen P. The specificities of protein kinase inhibitors: an update. Biochemical Journal. 371: 199-204. PMID 12534346 DOI: 10.1042/Bj20021535  0.54
2002 Rousseau S, Morrice N, Peggie M, Campbell DG, Gaestel M, Cohen P. Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs. The Embo Journal. 21: 6505-14. PMID 12456657 DOI: 10.1093/Emboj/Cdf639  0.362
2002 Yun CC, Palmada M, Embark HM, Fedorenko O, Feng Y, Henke G, Setiawan I, Boehmer C, Weinman EJ, Sandrasagra S, Korbmacher C, Cohen P, Pearce D, Lang F. The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1. Journal of the American Society of Nephrology : Jasn. 13: 2823-30. PMID 12444200 DOI: 10.1097/01.Asn.0000035085.54451.81  0.335
2002 Toska K, Kleppe R, Cohen P, Haavik J. Phosphorylation of tyrosine hydroxylase in isolated mice adrenal glands. Annals of the New York Academy of Sciences. 971: 66-8. PMID 12438091 DOI: 10.1111/j.1749-6632.2002.tb04435.x  0.405
2002 Toska K, Kleppe R, Armstrong CG, Morrice NA, Cohen P, Haavik J. Regulation of tyrosine hydroxylase by stress-activated protein kinases Journal of Neurochemistry. 83: 775-783. PMID 12421349 DOI: 10.1046/J.1471-4159.2002.01172.X  0.553
2002 Velasco G, Armstrong C, Morrice N, Frame S, Cohen P. Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin Febs Letters. 527: 101-104. PMID 12220642 DOI: 10.1016/S0014-5793(02)03175-7  0.568
2002 Knebel A, Haydon CE, Morrice N, Cohen P. Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways. Biochemical Journal. 367: 525-532. PMID 12171600 DOI: 10.1042/Bj20020916  0.553
2002 Cohen P. Protein kinases--the major drug targets of the twenty-first century? Nature Reviews Drug Discovery. 1: 309-315. PMID 12120283 DOI: 10.1038/Nrd773  0.49
2002 Cohen P. Protein kinases--the major drug targets of the twenty-first century? Nature Reviews. Drug Discovery. 1: 309-15. PMID 12120282 DOI: 10.1038/nrd773  0.359
2002 Ross H, Armstrong CG, Cohen P. A non-radioactive method for the assay of many serine/threonine-specific protein kinases Biochemical Journal. 366: 977-981. PMID 12119045 DOI: 10.1042/Bj20020786  0.506
2002 Cohen P. The origins of protein phosphorylation Nature Cell Biology. 4. PMID 11988757 DOI: 10.1038/Ncb0502-E127  0.517
2002 Rena G, Woods YL, Prescott AR, Peggie M, Unterman TG, Williams MR, Cohen P. Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. The Embo Journal. 21: 2263-71. PMID 11980723 DOI: 10.1093/Emboj/21.9.2263  0.513
2002 Wiggin GR, Soloaga A, Foster JM, Murray-Tait V, Cohen P, Arthur JSC. MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts Molecular and Cellular Biology. 22: 2871-2881. PMID 11909979 DOI: 10.1128/Mcb.22.8.2871-2881.2002  0.408
2002 Trotter L, Panton W, Hajimohamadreza I, Petalidis L, Ward R, Fleming Y, Armstrong CG, Cohen P, Karran EH, Kinloch RA. Mitogen-activated protein kinase kinase 7 is activated during low potassium-induced apoptosis in rat cerebellar granule neurons Neuroscience Letters. 320: 29-32. PMID 11849756 DOI: 10.1016/S0304-3940(02)00005-8  0.465
2002 Haydon CE, Watt PW, Morrice N, Knebel A, Gaestel M, Cohen P. Identification of a phosphorylation site on skeletal muscle myosin light chain kinase that becomes phosphorylated during muscle contraction Archives of Biochemistry and Biophysics. 397: 224-231. PMID 11795875 DOI: 10.1006/Abbi.2001.2625  0.536
2002 Rena G, Woods YL, Prescott AR, Peggie M, Unterman TG, Williams MR, Cohen P. IGF-1 induces phosphorylation of two novel residues of FKHR Biochemical Society Transactions. 30: A64-A64. DOI: 10.1042/Bst030A064  0.445
2001 Lang F, Cohen P. Regulation and Physiological Roles of Serum- and Glucocorticoid-Induced Protein Kinase Isoforms Science Signaling. 2001. PMID 11707620 DOI: 10.1126/Stke.2001.108.Re17  0.559
2001 Fagerholm S, Morrice N, Gahmberg CG, Cohen P. Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes. The Journal of Biological Chemistry. 277: 1728-38. PMID 11700305 DOI: 10.1074/jbc.M106856200  0.397
2001 Martin JL, Avkiran M, Quinlan RA, Cohen P, Marber MS. Antiischemic effects of SB203580 are mediated through the inhibition of p38α mitogen-activated protein kinase: Evidence from ectopic expression of an inhibition-resistant kinase Circulation Research. 89: 750-752. PMID 11679403 DOI: 10.1161/Hh2101.099504  0.438
2001 Caivano M, Gorgoni B, Cohen P, Poli V. The Induction of Cyclooxygenase-2 mRNA in Macrophages Is Biphasic and Requires both CCAAT Enhancer-binding protein β (C/EBPβ) and C/EBPδ Transcription Factors Journal of Biological Chemistry. 276: 48693-48701. PMID 11668179 DOI: 10.1074/Jbc.M108282200  0.343
2001 Cohen P. The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture. European Journal of Biochemistry. 268: 5001-10. PMID 11589691 DOI: 10.1046/J.0014-2956.2001.02473.X  0.528
2001 Cohen P, Frame S. The renaissance of GSK3. Nature Reviews Molecular Cell Biology. 2: 769-776. PMID 11584304 DOI: 10.1038/35096075  0.425
2001 Frame S, Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochemical Journal. 359: 1-16. PMID 11563964 DOI: 10.1042/0264-6021:3590001  0.491
2001 Knebel A, Morrice N, Cohen P. A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38δ The Embo Journal. 20: 4360-4369. PMID 11500363 DOI: 10.1093/Emboj/20.16.4360  0.576
2001 Mody N, Leitch J, Armstrong C, Dixon J, Cohen P. Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway. Febs Letters. 502: 21-4. PMID 11478941 DOI: 10.1016/S0014-5793(01)02651-5  0.481
2001 Frame S, Cohen P, Biondi RM. A Common Phosphate Binding Site Explains the Unique Substrate Specificity of GSK3 and Its Inactivation by Phosphorylation Molecular Cell. 7: 1321-1327. PMID 11430833 DOI: 10.1016/S1097-2765(01)00253-2  0.467
2001 Woods YL, Cohen P, Becker W, Jakes R, Goedert M, Wang X, Proud CG. The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. The Biochemical Journal. 355: 609-15. PMID 11311121 DOI: 10.1042/Bj3550609  0.546
2001 Woods YL, Rena G, Morrice N, Barthel A, Becker W, Guo S, Unterman TG, Cohen P. The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site. Biochemical Journal. 355: 597-607. PMID 11311120 DOI: 10.1042/Bj3550597  0.54
2001 Rena G, Prescott AR, Guo S, Cohen P, Unterman TG. Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting. The Biochemical Journal. 354: 605-12. PMID 11237865 DOI: 10.1042/0264-6021:3540605  0.527
2001 Fagerholm SC, Prescott A, Cohen P, Gahmberg CG. An essential role for calmodulin in regulating human T cell aggregation. Febs Letters. 491: 131-136. PMID 11226435 DOI: 10.1016/S0014-5793(01)02182-2  0.317
2001 Cohen P. The regulation of protein function by multisite phosphorylation--a 25 year update. Trends in Biochemical Sciences. 25: 596-601. PMID 11116185 DOI: 10.1016/S0968-0004(00)01712-6  0.483
2001 Cheung PCF, Trinkle-Mulcahy L, Cohen P, Lucocq JM. Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi. Biochemical Journal. 355: 113-121. DOI: 10.1042/Bj3550113  0.314
2000 Fleming Y, Armstrong CG, Morrice N, Paterson A, Goedert M, Cohen P. Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. The Biochemical Journal. 352: 145-54. PMID 11062067 DOI: 10.1042/Bj3520145  0.55
2000 Arthur JSC, Cohen P. MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells Febs Letters. 482: 44-48. PMID 11018520 DOI: 10.1016/S0014-5793(00)02031-7  0.524
2000 Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors Biochemical Journal. 351: 95-105. PMID 10998351 DOI: 10.1042/0264-6021:3510095  0.511
2000 Hefner Y, Borsch-Haubold AG, Murakami M, Wilde JI, Pasquet S, Schieltz D, Ghomashchi F, Yates JR, Armstrong CG, Paterson A, Cohen P, Fukunaga R, Hunter T, Kudo I, Watson SP, et al. Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases. The Journal of Biological Chemistry. 275: 37542-51. PMID 10978317 DOI: 10.1074/Jbc.M003395200  0.545
2000 Williams MR, Arthur JSC, Balendran A, Van der Kaay J, Poli V, Cohen P, Alessi DR. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells Current Biology. 10: 439-448. PMID 10801415 DOI: 10.1016/S0960-9822(00)00441-3  0.538
2000 Caivano M, Cohen P. Role of Mitogen-Activated Protein Kinase Cascades in Mediating Lipopolysaccharide-Stimulated Induction of Cyclooxygenase-2 and IL-1β in RAW264 Macrophages Journal of Immunology. 164: 3018-3025. PMID 10706690 DOI: 10.4049/Jimmunol.164.6.3018  0.45
2000 Walker KS, Watt PW, Cohen P. Phosphorylation of the skeletal muscle glycogen-targetting subunit of protein phosphatase 1 in response to adrenaline in vivo Febs Letters. 466: 121-124. PMID 10648825 DOI: 10.1016/S0014-5793(99)01771-8  0.537
2000 Kovarik P, Stoiber D, Eyers PA, Menghini R, Neininger A, Gaestel M, Cohen P, Decker T. Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 96: 13956-61. PMID 10570180 DOI: 10.1073/Pnas.96.24.13956  0.507
2000 Lizcano JM, Morrice N, Cohen P. Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155. Biochemical Journal. 349: 547-557. DOI: 10.1042/Bj3490547  0.546
2000 Badawi C, Gamper N, Huber S, Fillon S, Lepple-Wienhues A, Waldegger S, Wagner C, Cohen P, Moschen I, Setiawan I, Feng Y, Stegen C, Friedrich B, Bröer S, Szabo I, et al. Kinases, cell volume, and the regulation of epithelial transport Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 126: 86. DOI: 10.1016/S1095-6433(00)80170-1  0.38
1999 Chang ACY, Sohlberg B, Trinkle-Mulcahy L, Claverie-Martin F, Cohen P, Cohen SN. Alternative splicing regulates the production of ARD-1 endoribonuclease and NIPP-1, an inhibitor of protein phosphatase-1, as isoforms encoded by the same gene Gene. 240: 45-55. PMID 10564811 DOI: 10.1016/S0378-1119(99)00435-7  0.359
1999 Shaw M, Cohen P. Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells1 Febs Letters. 461: 120-124. PMID 10561508 DOI: 10.1016/S0014-5793(99)01434-9  0.503
1999 Börsch-Haubold AG, Ghomashchi F, Pasquet S, Goedert M, Cohen P, Gelb MH, Watson SP. Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways. European Journal of Biochemistry / Febs. 265: 195-203. PMID 10491174 DOI: 10.1046/J.1432-1327.1999.00722.X  0.526
1999 Thomas GM, Frame S, Goedert M, Nathke I, Polakis P, Cohen P. A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin. Febs Letters. 458: 247-51. PMID 10481074 DOI: 10.1016/S0014-5793(99)01161-8  0.429
1999 Hall-Jackson CA, Eyers PA, Cohen P, Goedert M, Boyle FT, Hewitt N, Plant H, Hedge P. Paradoxical activation of Raf by a novel Raf inhibitor. Chemistry & Biology. 6: 559-68. PMID 10421767 DOI: 10.1016/S1074-5521(99)80088-X  0.466
1999 Cohen P. The development and therapeutic potential of protein kinase inhibitors. Current Opinion in Chemical Biology. 3: 459-65. PMID 10419844 DOI: 10.1016/S1367-5931(99)80067-2  0.459
1999 Paul A, Cuenda A, Bryant CE, Murray J, Chilvers ER, Cohen P, Gould GW, Plevin R. Involvement of Mitogen-Activated Protein Kinase Homologues in the Regulation of Lipopolysaccharide-Mediated Induction of Cyclo-oxygenase-2 but not Nitric Oxide Synthase in RAW 264.7 Macrophages Cellular Signalling. 11: 491-497. PMID 10405759 DOI: 10.1016/S0898-6568(99)00018-2  0.456
1999 Eyers PA, van den IJssel P, Quinlan RA, Goedert M, Cohen P. Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580. Febs Letters. 451: 191-6. PMID 10371163 DOI: 10.1016/S0014-5793(99)00552-9  0.506
1999 Lal AS, Clifton AD, Rouse J, Segal AW, Cohen P. Activation of the neutrophil NADPH oxidase is inhibited by SB 203580, a specific inhibitor of SAPK2/p38. Biochemical and Biophysical Research Communications. 259: 465-70. PMID 10362531 DOI: 10.1006/Bbrc.1999.0759  0.394
1999 Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T. Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. Journal of Biological Chemistry. 274: 17184-17192. PMID 10358076 DOI: 10.1074/Jbc.274.24.17184  0.367
1999 Rena G, Guo S, Cichy SC, Unterman TG, Cohen P. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. Journal of Biological Chemistry. 274: 17179-17183. PMID 10358075 DOI: 10.1074/Jbc.274.24.17179  0.539
1999 Hall-Jackson CA, Goedert M, Hedge P, Cohen P. Effect of SB 203580 on the activity of c-Raf in vitro and in vivo. Oncogene. 18: 2047-54. PMID 10321729 DOI: 10.1038/Sj.Onc.1202603  0.493
1999 Cohen P. The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction Philosophical Transactions of the Royal Society B. 354: 485-495. PMID 10212493 DOI: 10.1098/Rstb.1999.0399  0.483
1999 Hasegawa M, Cuenda A, Spillantini MG, Thomas GM, Buée-Scherrer V, Cohen P, Goedert M. Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. The Journal of Biological Chemistry. 274: 12626-31. PMID 10212242 DOI: 10.1074/Jbc.274.18.12626  0.528
1999 Cuenda A, Cohen P. Stress-activated Protein Kinase-2/p38 and a Rapamycin-sensitive Pathway Are Required for C2C12 Myogenesis Journal of Biological Chemistry. 274: 4341-4346. PMID 9933636 DOI: 10.1074/Jbc.274.7.4341  0.49
1999 Shaw M, Cohen P, Alessi DR. The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2. The Biochemical Journal. 241-6. PMID 9806907 DOI: 10.1042/Bj3360241  0.496
1999 Kobayashi T, Deak M, Morrice N, Cohen P. Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase. Biochemical Journal. 344: 189-197. DOI: 10.1042/Bj3440189  0.542
1999 Kobayashi T, Cohen P. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochemical Journal. 339: 319-328. DOI: 10.1042/Bj3390319  0.552
1999 Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1. Biochemical Journal. 337: 575-583. DOI: 10.1042/Bj3370575  0.376
1998 Lawler S, Fleming Y, Goedert M, Cohen P. Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro. Current Biology : Cb. 8: 1387-90. PMID 9889102 DOI: 10.1016/S0960-9822(98)00019-0  0.536
1998 Moorhead G, Johnson D, Morrice N, Cohen P. The major myosin phosphatase in skeletal muscle is a complex between the beta-isoform of protein phosphatase 1 and the MYPT2 gene product. Febs Letters. 438: 141-4. PMID 9827534 DOI: 10.1016/S0014-5793(98)01276-9  0.652
1998 Le Good JA, Ziegler WH, Parekh DB, Alessi DR, Cohen P, Parker PJ. Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science (New York, N.Y.). 281: 2042-5. PMID 9748166 DOI: 10.1126/Science.281.5385.2042  0.547
1998 Doza YN, Hall-Jackson CA, Cohen P. Arsenite blocks growth factor induced activation of the MAP kinase cascade, upstream of Ras and downstream of Grb2-Sos. Oncogene. 17: 19-24. PMID 9671310 DOI: 10.1038/Sj.Onc.1202168  0.354
1998 Cohen P, Goedert M. Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid. Chemistry & Biology. 5: R161-4. PMID 9662509 DOI: 10.1016/S1074-5521(98)90068-0  0.468
1998 Eyers PA, Craxton M, Morrice N, Cohen P, Goedert M. Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. Chemistry & Biology. 5: 321-8. PMID 9653550 DOI: 10.1016/S1074-5521(98)90170-3  0.539
1998 Alessi DR, Cohen P. Mechanism of activation and function of protein kinase B. Current Opinion in Genetics & Development. 8: 55-62. PMID 9529606 DOI: 10.1016/S0959-437X(98)80062-2  0.512
1998 Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide dependent protein kinase-1 in vitro: Comparison with protein kinase B α Biochemical Journal. 331: 299-308. PMID 9512493 DOI: 10.1042/Bj3310299  0.513
1998 Dalby KN, Morrice N, Caudwell FB, Avruch J, Cohen P. Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK. The Journal of Biological Chemistry. 273: 1496-505. PMID 9430688 DOI: 10.1074/Jbc.273.3.1496  0.68
1997 Cohen P. The search for physiological substrates of MAP and SAP kinases in mammalian cells Trends in Cell Biology. 7: 353-361. PMID 17708980 DOI: 10.1016/S0962-8924(97)01105-7  0.511
1997 Kreivi JP, Trinkle-Mulcahy L, Lyon CE, Morrice NA, Cohen P, Lamond AI. Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity Febs Letters. 420: 57-62. PMID 9450550 DOI: 10.1016/S0014-5793(97)01485-3  0.344
1997 Thomas GM, Haavik J, Cohen P. A stress-activated kinase cascade can mediate the activation of tyrosine hydroxylase in chromaffin cells Biochemical Society Transactions. 25: S571. PMID 9449999 DOI: 10.1042/Bst025S571  0.508
1997 Cuenda A, Goedert M, Craxton M, Jakes R, Cohen P. Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6). Biochemical Society Transactions. 25: S569. PMID 9449997 DOI: 10.1042/Bst025S569  0.439
1997 Armstrong CG, Browne GJ, Cohen P, Cohen PTW. PPP1R6, a novel member: Of the family of glycogen-targetting subunits of protein phosphatase 1 Febs Letters. 418: 210-214. PMID 9414128 DOI: 10.1016/S0014-5793(97)01385-9  0.36
1997 Andjelković M, Alessi DR, Meier R, Fernandez A, Lamb NJ, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. Role of translocation in the activation and function of protein kinase B. The Journal of Biological Chemistry. 272: 31515-24. PMID 9395488 DOI: 10.1074/Jbc.272.50.31515  0.486
1997 Hazzalin CA, Cuenda A, Cano E, Cohen P, Mahadevan LC. Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli Oncogene. 15: 2321-2331. PMID 9393876 DOI: 10.1038/Sj.Onc.1201403  0.421
1997 Shaw M, Cohen P, Alessi DR. Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216. Febs Letters. 416: 307-11. PMID 9373175 DOI: 10.1016/S0014-5793(97)01235-0  0.439
1997 Lawler S, Cuenda A, Goedert M, Cohen P. SKK4, a novel activator of stress-activated protein kinase-1 (SAPK1/JNK). Febs Letters. 414: 153-8. PMID 9305750 DOI: 10.1016/S0014-5793(97)00990-3  0.48
1997 Thomas G, Haavik J, Cohen P. Participation of a stress-activated protein kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells European Journal of Biochemistry. 247: 1180-1189. PMID 9288946 DOI: 10.1111/J.1432-1033.1997.01180.X  0.508
1997 Cohen P, Alessi DR, Cross DA. PDK1, one of the missing links in insulin signal transduction? Febs Letters. 410: 3-10. PMID 9247112 DOI: 10.1016/S0014-5793(97)00490-0  0.493
1997 Goedert M, Cuenda A, Craxton M, Jakes R, Cohen P. Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. The Embo Journal. 16: 3563-71. PMID 9218798 DOI: 10.1093/Emboj/16.12.3563  0.512
1997 Goedert M, Hasegawa M, Jakes R, Lawler S, Cuenda A, Cohen P. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases. Febs Letters. 409: 57-62. PMID 9199504 DOI: 10.1016/S0014-5793(97)00483-3  0.478
1997 Egloff MP, Johnson DF, Moorhead G, Cohen PT, Cohen P, Barford D. Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. The Embo Journal. 16: 1876-87. PMID 9155014 DOI: 10.1093/Emboj/16.8.1876  0.646
1997 Cross DA, Watt PW, Shaw M, van der Kaay J, Downes CP, Holder JC, Cohen P. Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue. Febs Letters. 406: 211-5. PMID 9109420 DOI: 10.1016/S0014-5793(97)00240-8  0.452
1997 Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, Cohen P. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Current Biology : Cb. 7: 261-9. PMID 9094314 DOI: 10.1016/S0960-9822(06)00122-9  0.564
1997 Cuenda A, Cohen P, Buée-Scherrer V, Goedert M. Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38). The Embo Journal. 16: 295-305. PMID 9029150 DOI: 10.1093/Emboj/16.2.295  0.481
1997 Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. Febs Letters. 399: 333-8. PMID 8985174 DOI: 10.1016/S0014-5793(96)01370-1  0.542
1996 MacKintosh C, Garton AJ, McDonnell A, Barford D, Cohen PT, Tonks NK, Cohen P. Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. Febs Letters. 397: 235-8. PMID 8955354 DOI: 10.1016/S0014-5793(96)01175-1  0.727
1996 Hazzalin CA, Cano E, Cuenda A, Barratt MJ, Cohen P, Mahadevan LC. p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient Current Biology. 6: 1028-1031. PMID 8805335 DOI: 10.1016/S0960-9822(02)00649-8  0.423
1996 Cohen P. Dissection of Protein Kinase Cascades That Mediate Cellular Response to Cytokines and Cellular Stress Advances in Pharmacology. 36: 15-27. PMID 8783552 DOI: 10.1016/S1054-3589(08)60574-8  0.521
1996 Clifton AD, Young PR, Cohen P. A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress. Febs Letters. 392: 209-14. PMID 8774846 DOI: 10.1016/0014-5793(96)00816-2  0.528
1996 Johnson DF, Moorhead G, Caudwell FB, Cohen P, Chen YH, Chen MX, Cohen PT. Identification of protein-phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits. European Journal of Biochemistry / Febs. 239: 317-25. PMID 8706735 DOI: 10.1111/J.1432-1033.1996.0317U.X  0.642
1996 Gordon RD, Leighton IA, Campbell DG, Cohen P, Creaney A, Wilton DC, Masters DJ, Ritchie GA, Mott R, Taylor IW, Bundell KR, Douglas L, Morten J, Needham M. Cloning and expression of cystolic phospholipase A2 (cPLA2) and a naturally occurring variant. Phosphorylation of Ser505 of recombinant cPLA2 by p42 mitogen-activated protein kinase results in an increase in specific activity. European Journal of Biochemistry / Febs. 238: 690-7. PMID 8706669 DOI: 10.1111/J.1432-1033.1996.0690W.X  0.531
1996 Meier R, Rouse J, Cuenda A, Nebreda AR, Cohen P. Cellular Stresses and Cytokines Activate Multiple Mitogen‐Activated‐Protein Kinase Kinase Homologues in PC12 and KB Cells Febs Journal. 236: 796-805. PMID 8665897 DOI: 10.1111/J.1432-1033.1996.00796.X  0.534
1996 Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature. 378: 785-9. PMID 8524413 DOI: 10.1038/378785A0  0.54
1996 Alessi DR, Cohen P, Ashworth A, Cowley S, Leevers SJ, Marshall CJ. Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf. Methods in Enzymology. 255: 279-90. PMID 8524112 DOI: 10.1016/S0076-6879(95)55031-3  0.522
1996 Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA. Mechanism of activation of protein kinase B by insulin and IGF-1. The Embo Journal. 15: 6541-6551. DOI: 10.1002/J.1460-2075.1996.Tb01045.X  0.507
1996 Cuenda A, Alonso G, Morrice N, Jones M, Meier R, Cohen P, Nebreda AR. Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells. The Embo Journal. 15: 4156-4164. DOI: 10.1002/J.1460-2075.1996.Tb00790.X  0.477
1996 Beyaert R, Cuenda A, Berghe WV, Plaisance S, Lee JC, Haegeman G, Cohen P, Fiers W. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. The Embo Journal. 15: 1914-1923. DOI: 10.1002/J.1460-2075.1996.Tb00542.X  0.48
1995 Baxter RM, Cohen P, Obermeier A, Ullrich A, Downes CP, Doza YN. Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells. European Journal of Biochemistry / Febs. 234: 84-91. PMID 8529673 DOI: 10.1111/J.1432-1033.1995.084_C.X  0.495
1995 Chen YH, Chen MX, Alessi DR, Campbell DG, Shanahan C, Cohen P, Cohen PT. Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M. Febs Letters. 356: 51-5. PMID 7988720 DOI: 10.1016/0014-5793(94)01231-8  0.337
1995 Lowenstein PR, Shering AF, MacDougall LK, Cohen P. Immunolocalisation of protein phosphatase inhibitor-1 in the cerebral cortex of the rat, cat and ferret. Brain Research. 676: 80-92. PMID 7796181 DOI: 10.1016/0006-8993(95)00091-4  0.321
1995 Alessi DR, Gomez N, Moorhead G, Lewis T, Keyse SM, Cohen P. Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines. Current Biology : Cb. 5: 283-95. PMID 7780739 DOI: 10.1016/S0960-9822(95)00059-5  0.704
1995 Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR, Lee JC. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 Febs Letters. 364: 229-233. PMID 7750577 DOI: 10.1016/0014-5793(95)00357-F  0.523
1995 Doza YN, Cuenda A, Thomas GM, Cohen P, Nebreda AR. Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells Febs Letters. 364: 223-228. PMID 7750576 DOI: 10.1016/0014-5793(95)00346-B  0.492
1995 Moorhead G, MacKintosh C, Morrice N, Cohen P. Purification of the hepatic glycogen-associated form of protein phosphatase-1 by microcystin-Sepharose affinity chromatography. Febs Letters. 362: 101-5. PMID 7720853 DOI: 10.1016/0014-5793(95)00197-H  0.745
1995 MacKintosh RW, Dalby KN, Campbell DG, Cohen PT, Cohen P, MacKintosh C. The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1. Febs Letters. 371: 236-40. PMID 7556599 DOI: 10.1016/0014-5793(95)00888-G  0.709
1995 Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo Journal of Biological Chemistry. 270: 27489-27494. PMID 7499206 DOI: 10.1074/Jbc.270.46.27489  0.478
1995 Doherty MJ, Moorhead G, Morrice N, Cohen P, Cohen PT. Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1. Febs Letters. 375: 294-8. PMID 7498521 DOI: 10.1016/0014-5793(95)01184-G  0.659
1995 Leighton IA, Dalby KN, Caudwell FB, Cohen PT, Cohen P. Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation. Febs Letters. 375: 289-93. PMID 7498520 DOI: 10.1016/0014-5793(95)01170-J  0.651
1995 Gould GW, Cuenda A, Thomson FJ, Cohen P. The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells. Biochemical Journal. 311: 735-738. PMID 7487926 DOI: 10.1042/Bj3110735  0.467
1995 Ben-Levy R, Leighton IA, Doza YN, Attwood P, Morrice N, Marshall CJ, Cohen P. Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2. The Embo Journal. 14: 5920-5930. DOI: 10.1002/J.1460-2075.1995.Tb00280.X  0.529
1994 Sutherland C, Cohen P. The alpha-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro. Febs Letters. 338: 37-42. PMID 8307153 DOI: 10.1016/0014-5793(94)80112-6  0.523
1994 Saito Y, Gomez N, Campbell DG, Ashworth A, Marshall CJ, Cohen P. The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor-stimulated rat phaeochromocytoma (PC12) cells. Febs Letters. 341: 119-124. PMID 8137910 DOI: 10.1016/0014-5793(94)80252-1  0.48
1994 Cohen P. The discovery of protein phosphatases: From chaos and confusion to an understanding of their role in cell regulation and human disease Bioessays. 16: 583-588. PMID 8086007 DOI: 10.1002/Bies.950160812  0.337
1994 Traverse S, Cohen P. Identification of a latent MAP kinase kinase kinase in PC12 cells as B-raf. Febs Letters. 350: 13-18. PMID 8062910 DOI: 10.1016/0014-5793(94)00723-3  0.467
1994 Traverse S, Seedorf K, Paterson H, Marshall CJ, Cohen P, Ullrich A. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Current Biology. 4: 694-701. PMID 7953555 DOI: 10.1016/S0960-9822(00)00154-8  0.391
1994 Saito Y, Vandenheede J, Cohen P. The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells. Biochemical Journal. 303: 27-31. PMID 7945252 DOI: 10.1042/Bj3030027  0.536
1994 Cross DAE, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P. The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf Biochemical Journal. 303: 21-26. PMID 7945242 DOI: 10.1042/Bj3030021  0.521
1994 Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell. 78: 1027-1037. PMID 7923353 DOI: 10.1016/0092-8674(94)90277-1  0.528
1993 Sutherland C, Campbell DG, Cohen P. Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2. Identification of two threonines phosphorylated during activation by mitogen-activated protein kinase. European Journal of Biochemistry. 212: 581-8. PMID 8444194 DOI: 10.1111/J.1432-1033.1993.Tb17696.X  0.568
1993 Ferrigno P, Langan TA, Cohen P. Protein phosphatase 2A1 is the major enzyme in vertebrate cell extracts that dephosphorylates several physiological substrates for cyclin-dependent protein kinases. Molecular Biology of the Cell. 4: 669-77. PMID 8400454 DOI: 10.1091/mbc.4.7.669  0.428
1993 Hubbard MJ, Cohen P. On target with a new mechanism for the regulation of protein phosphorylation. Trends in Biochemical Sciences. 18: 172-7. PMID 8392229 DOI: 10.1016/0968-0004(93)90109-Z  0.533
1993 Alessi DR, Street AJ, Cohen P, Cohen PT. Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme. European Journal of Biochemistry. 213: 1055-66. PMID 8389292 DOI: 10.1111/J.1432-1033.1993.Tb17853.X  0.447
1993 Donella-Deana A, Lavoinne A, Marin O, Pinna LA, Cohen P. An analysis of the substrate specificity of insulin-stimulated protein kinase-1, a mammalian homologue of S6 kinase-II. Biochimica Et Biophysica Acta. 1178: 189-93. PMID 8347677 DOI: 10.1016/0167-4889(93)90008-D  0.493
1993 Clarke PR, Siddhanti SR, Cohen P, Blackshear PJ. Okadaic acid-sensitive protein phosphatases dephosphorylate MARCKS, a major protein kinase C substrate Febs Letters. 336: 37-42. PMID 8262213 DOI: 10.1016/0014-5793(93)81604-X  0.554
1993 Sutherland C, Leighton IA, Cohen P. Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling. The Biochemical Journal. 15-9. PMID 8250835 DOI: 10.1042/Bj2960015  0.443
1993 Merrall NW, Plevin RJ, Stokoe D, Cohen P, Nebreda AR, Gould GW. Mitogen-activated protein kinase (MAP kinase), MAP kinase kinase and c-Mos stimulate glucose transport in Xenopus oocytes. Biochemical Journal. 295: 351-355. PMID 8240233 DOI: 10.1042/Bj2950351  0.473
1993 Cohen P. Dissection of the Protein Phosphorylation Cascades Involved in Insulin and Growth Factor Action Biochemical Society Transactions. 21: 555-567. PMID 8224471 DOI: 10.1042/Bst0210555  0.52
1993 Nebreda AR, Hill C, Gomez N, Cohen P, Hunt T. The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo. Febs Letters. 333: 183-7. PMID 8224161 DOI: 10.1016/0014-5793(93)80401-F  0.519
1993 Leighton IA, Curmi P, Campbell DG, Cohen P, Sobel A. The phosphorylation of stathmin by MAP kinase Molecular and Cellular Biochemistry. 127: 151-156. PMID 7935347 DOI: 10.1007/Bf01076766  0.487
1993 Sutherland C, Alterio J, Campbell DG, Le Bourdellès B, Mallet J, Haavik J, Cohen P. Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2. European Journal of Biochemistry. 217: 715-22. PMID 7901013 DOI: 10.1111/J.1432-1033.1993.Tb18297.X  0.546
1992 Nakielny S, Campbell DG, Cohen P. MAP kinase kinase from rabbit skeletal muscle. A novel dual specificity enzyme showing homology to yeast protein kinases involved in pheromone-dependent signal transduction. Febs Letters. 308: 183-9. PMID 1499729 DOI: 10.1016/0014-5793(92)81271-M  0.566
1992 Gomez N, Traverse S, Cohen P. Identification of a MAP kinase kinase kinase in phaeochromocytoma (PC12) cells Febs Letters. 314: 461-465. PMID 1468586 DOI: 10.1016/0014-5793(92)81527-S  0.523
1992 Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry. 31: 3896-901. PMID 1373650 DOI: 10.1021/Bi00131A002  0.593
1992 Dent P, MacDougall LK, Mackintosh C, Campbell DG, Cohen P. A myofibrillar protein phosphatase from rabbit skeletal muscle contains the β isoform of protein phosphatase-1 complexed to a regulatory subunit which greatly enhances the dephosphorylation of myosin European Journal of Biochemistry. 210: 1037-1044. PMID 1336456 DOI: 10.1111/J.1432-1033.1992.Tb17509.X  0.699
1992 Alessi D, Macdougall LK, Sola MM, Ikebe M, Cohen P. The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1. Febs Journal. 210: 1023-1035. PMID 1336455 DOI: 10.1111/J.1432-1033.1992.Tb17508.X  0.484
1992 Cohen P. Signal integration at the level of protein kinases, protein phosphatases and their substrates Trends in Biochemical Sciences. 17: 408-413. PMID 1333658 DOI: 10.1016/0968-0004(92)90010-7  0.548
1992 Stokoe D, Engel K, Campbell DG, Cohen P, Gaestel M. Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. Febs Letters. 313: 307-13. PMID 1332886 DOI: 10.1016/0014-5793(92)81216-9  0.505
1992 Mermoud JE, Cohen P, Lamond AI. Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing. Nucleic Acids Research. 20: 5263-9. PMID 1331983 DOI: 10.1093/Nar/20.20.5263  0.462
1992 Cohen P, Campbell DG, Dent P, Gomez N, Lavoinne A, Nakielny S, Stokoe D, Sutherland C, Traverse S. Dissection of the protein kinase cascades involved in insulin and nerve growth factor action. Biochemical Society Transactions. 20: 671-674. PMID 1330784 DOI: 10.1042/Bst0200671  0.383
1992 Goedert M, Cohen ES, Jakes R, Cohen P. p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]. Febs Letters. 312: 95-9. PMID 1330687 DOI: 10.1016/0014-5793(92)81418-L  0.48
1992 Howe LR, Leevers SJ, Gómez N, Nakielny S, Cohen P, Marshall CJ. Activation of the MAP kinase pathway by the protein kinase raf Cell. 71: 335-342. PMID 1330321 DOI: 10.1016/0092-8674(92)90361-F  0.504
1992 Daum G, Schmid B, MacKintosh C, Cohen P, Hofer HW. Characterization of the major phosphofructokinase-dephosphorylating protein phosphatases from Ascaris suum muscle. Biochimica Et Biophysica Acta. 1122: 23-32. PMID 1321672 DOI: 10.1016/0167-4838(92)90122-T  0.716
1992 Woodman PG, Mundy DI, Cohen P, Warren G. Cell-free fusion of endocytic vesicles is regulated by phosphorylation. The Journal of Cell Biology. 116: 331-8. PMID 1309811 DOI: 10.1083/Jcb.116.2.331  0.541
1992 Nakielny S, Cohen P, Wu J, Sturgill T. MAP kinase activator from insulin-stimulated skeletal muscle is a protein threonine/tyrosine kinase The Embo Journal. 11: 2123-2129. DOI: 10.1002/J.1460-2075.1992.Tb05271.X  0.537
1991 Gibson BW, Cohen P. Liquid secondary ion mass spectrometry of phosphorylated and sulfated peptides and proteins. Methods in Enzymology. 193: 480-501. PMID 2127451 DOI: 10.1016/0076-6879(90)93434-M  0.497
1991 Cohen P, Gibson BW, Holmes CFB. Analysis of the in vivo phosphorylation states of proteins by fast atom bombardment mass spectrometry and other techniques Methods in Enzymology. 201: 153-168. PMID 1943762 DOI: 10.1016/0076-6879(91)01015-T  0.445
1991 Smythe C, Cohen P. The discovery of glycogenin and the priming mechanism for glycogen biogenesis. European Journal of Biochemistry. 200: 625-31. PMID 1915338 DOI: 10.1111/J.1432-1033.1991.Tb16225.X  0.424
1991 MacDougall LK, Jones LR, Cohen P. Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban European Journal of Biochemistry. 196: 725-734. PMID 1849481 DOI: 10.1111/J.1432-1033.1991.Tb15871.X  0.492
1991 MacKintosh C, Coggins J, Cohen P. Plant protein phosphatases. Subcellular distribution, detection of protein phosphatase 2C and identification of protein phosphatase 2A as the major quinate dehydrogenase phosphatase. The Biochemical Journal. 273: 733-8. PMID 1847622 DOI: 10.1042/Bj2730733  0.664
1991 Gómez N, Cohen P. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases Nature. 353: 170-173. PMID 1716348 DOI: 10.1038/353170A0  0.554
1991 Hubbard MJ, Cohen P. Targeting subunits for protein phosphatases. Methods in Enzymology. 201: 414-27. PMID 1658559 DOI: 10.1016/0076-6879(91)01038-4  0.524
1991 Cohen P. Classification of protein-serine/threonine phosphatases: identification and quantitation in cell extracts. Methods in Enzymology. 201: 389-398. PMID 1658556 DOI: 10.1016/0076-6879(91)01035-Z  0.514
1991 Doonan JH, MacKintosh C, Osmani S, Cohen P, Bai G, Lee EY, Morris NR. A cDNA encoding rabbit muscle protein phosphatase 1 alpha complements the Aspergillus cell cycle mutation, bimG11. The Journal of Biological Chemistry. 266: 18889-94. PMID 1655766  0.317
1991 Cohen P, Hardie DG. The actions of cyclic AMP on biosynthetic processes are mediated indirectly by cyclic AMP-dependent protein kinase. Biochimica Et Biophysica Acta. 1094: 292-9. PMID 1655040 DOI: 10.1016/0167-4889(91)90089-G  0.558
1991 Sola MM, Langan T, Cohen P. p34cdc2 phosphorylation sites in histone H1 are dephosphorylated by protein phosphatase 2A1. Biochimica Et Biophysica Acta. 1094: 211-6. PMID 1654119 DOI: 10.1016/0167-4889(91)90011-L  0.424
1991 Lavoinne A, Erikson E, Maller JL, Price DJ, Avruch J, Cohen P. Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II. European Journal of Biochemistry / Febs. 199: 723-8. PMID 1651243 DOI: 10.1111/J.1432-1033.1991.Tb16176.X  0.528
1991 Nakielny S, Campbell DG, Cohen P. The molecular mechanism by which adrenalin inhibits glycogen synthesis. European Journal of Biochemistry. 199: 713-22. PMID 1651242 DOI: 10.1111/J.1432-1033.1991.Tb16175.X  0.503
1990 Hubbard MJ, Cohen P. Regulation of protein phosphatase-1G from rabbit skeletal muscle. 1. Phosphorylation by cAMP-dependent protein kinase at site 2 releases catalytic subunit from the glycogen-bound holoenzyme. European Journal of Biochemistry. 186: 701-9. PMID 2558013 DOI: 10.1111/J.1432-1033.1989.Tb15263.X  0.488
1990 Gómez N, Tonks NK, Morrison C, Harmar T, Cohen P. Evidence for communication between nerve growth factor and protein tyrosine phosphorylation. Febs Letters. 271: 119-22. PMID 2171996 DOI: 10.1016/0014-5793(90)80386-W  0.495
1990 MacKintosh C, Beattie KA, Klumpp S, Cohen P, Codd GA. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. Febs Letters. 264: 187-92. PMID 2162782 DOI: 10.1016/0014-5793(90)80245-E  0.694
1990 Hubbard MJ, Dent P, Smythe C, Cohen P. Targetting of protein phosphatase 1 to the sarcoplasmic reticulum of rabbit skeletal muscle by a protein that is very similar or identical to the G subunit that directs the enzyme to glycogen European Journal of Biochemistry. 189: 243-249. PMID 2159875 DOI: 10.1111/J.1432-1033.1990.Tb15483.X  0.523
1990 Cohen P, Holmes CF, Tsukitani Y. Okadaic acid: a new probe for the study of cellular regulation. Trends in Biochemical Sciences. 15: 98-102. PMID 2158158 DOI: 10.1016/0968-0004(90)90192-E  0.654
1990 Donella Deana A, Mac Gowan CH, Cohen P, Marchiori F, Meyer HE, Pinna LA. An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A. Biochimica Et Biophysica Acta. 1051: 199-202. PMID 2155667 DOI: 10.1016/0167-4889(90)90194-I  0.439
1990 Dent P, Campbell DG, Caudwell FB, Cohen P. Identification of three in vivo phosphorylation sites on the glycogen-binding subunit of protein phosphatase 1 from rabbit skeletal muscle, and their response to adrenaline Febs Letters. 259: 281-285. PMID 2152882 DOI: 10.1016/0014-5793(90)80027-G  0.411
1990 Smythe C, Watt P, Cohen P. Further studies on the role of glycogenin in glycogen biosynthesis. European Journal of Biochemistry. 189: 199-204. PMID 2110063 DOI: 10.1111/J.1432-1033.1990.Tb15477.X  0.367
1990 Klumpp S, Cohen P, Schultz JE. Chromatographic separation of four Ser/Thr-protein phosphatases from solubilized ciliary membranes of Paramecium tetraurelia by heparin-sepharose. Journal of Chromatography. 521: 179-86. PMID 1962786 DOI: 10.1016/0021-9673(90)85042-T  0.377
1990 Haystead TAJ, Moore F, Cohen P, Hardie DG. Roles of the AMP-activated and cyclic-AMP-dependent protein kinases in the adrenaline-induced inactivation of acetyl-CoA carboxylase in rat adipocytes European Journal of Biochemistry. 187: 199-205. PMID 1688796 DOI: 10.1111/J.1432-1033.1990.Tb15295.X  0.572
1989 MacDougall LK, Campbell DG, Hubbard MJ, Cohen P. Partial structure and hormonal regulation of rabbit liver inhibitor-1; distribution of inhibitor-1 and inhibitor-2 in rabbit and rat tissues. Biochimica Et Biophysica Acta. 1010: 218-26. PMID 2912504 DOI: 10.1016/0167-4889(89)90164-X  0.4
1989 Schelling D, Leader DP, Zammit VA, Cohen P. Distinct type-1 protein phosphatases are associated with hepatic glycogen and microsomes. Biochimica Et Biophysica Acta. 972: 221-31. PMID 2847806 DOI: 10.1016/0167-4889(88)90120-6  0.469
1989 Campbell DG, Cohen P. The amino acid sequence of rabbit skeletal muscle glycogenin. European Journal of Biochemistry. 185: 119-25. PMID 2806254 DOI: 10.1111/J.1432-1033.1989.Tb15090.X  0.372
1989 Haavik J, Schelling DL, Campbell DG, Andersson KK, Flatmark T, Cohen P. Identification of protein phosphatase 2A as the major tyrosine hydroxylase phosphatase in adrenal medulla and corpus striatum: evidence from the effects of okadaic acid. Febs Letters. 251: 36-42. PMID 2568951 DOI: 10.1016/0014-5793(89)81424-3  0.476
1989 Fowles C, Akhtar M, Cohen P. Interplay of phosphorylation and dephosphorylation in vision: protein phosphatases of bovine rod outer segments. Biochemistry. 28: 9385-9391. PMID 2558719 DOI: 10.1021/Bi00450A020  0.468
1989 Hubbard MJ, Cohen P. Regulation of protein phosphatase-1G from rabbit skeletal muscle. 2. Catalytic subunit translocation is a mechanism for reversible inhibition of activity toward glycogen-bound substrates. Febs Journal. 186: 711-716. PMID 2558014 DOI: 10.1111/J.1432-1033.1989.Tb15264.X  0.429
1989 MacKintosh C, Cohen P. Identification of high levels of type 1 and type 2A protein phosphatases in higher plants. The Biochemical Journal. 262: 335-9. PMID 2554892 DOI: 10.1042/Bj2620335  0.615
1989 Cohen P. The Structure And Regulation Of Protein Phosphatases Annual Review of Biochemistry. 58: 453-508. PMID 2549856 DOI: 10.1146/Annurev.Bi.58.070189.002321  0.529
1989 Cohen PTW, Cohen P. Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221. Biochemical Journal. 260: 931-934. PMID 2548489 DOI: 10.1042/Bj2600931  0.451
1989 Cohen P, Schelling DL, Stark MJR. Remarkable similarities between yeast and mammalian protein phosphatases. Febs Letters. 250: 601-606. PMID 2546813 DOI: 10.1016/0014-5793(89)80804-X  0.49
1989 Cohen P, Klumpp S, Schelling DL. An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues Febs Letters. 250: 596-600. PMID 2546812 DOI: 10.1016/0014-5793(89)80803-8  0.344
1989 Dent P, Campbell DG, Hubbard MJ, Cohen P. Multisite phosphorylation of the glycogen-binding subunit of protein phosphatase-1G by cyclic AMP-dependent protein kinase and glycogen synthase kinase-3 Febs Letters. 248: 67-72. PMID 2542090 DOI: 10.1016/0014-5793(89)80433-8  0.56
1989 Cohen PT, Schelling DL, da Cruz e Silva OB, Barker HM, Cohen P. The major type-1 protein phosphatase catalytic subunits are the same gene products in rabbit skeletal muscle and rabbit liver. Biochimica Et Biophysica Acta. 1008: 125-8. PMID 2541784 DOI: 10.1016/0167-4781(89)90181-4  0.405
1989 Hubbard MJ, Cohen P. The glycogen-binding subunit of protein phosphatase-1G from rabbit skeletal muscle. Further characterisation of its structure and glycogen-binding properties. European Journal of Biochemistry. 180: 457-65. PMID 2538333 DOI: 10.1111/J.1432-1033.1989.Tb14668.X  0.418
1989 Smythe C, Villar-Palasi C, Cohen P. Structural and functional studies on rabbit liver glycogenin. European Journal of Biochemistry. 183: 205-9. PMID 2526735 DOI: 10.1111/J.1432-1033.1989.Tb14914.X  0.356
1988 Garton AJ, Campbell DG, Cohen P, Yeaman SJ. Primary structure of the site on bovine hormone-sensitive lipase phosphorylated by cyclic AMP-dependent protein kinase Febs Letters. 229: 68-72. PMID 3345839 DOI: 10.1016/0014-5793(88)80799-3  0.546
1988 Pitcher J, Smythe C, Campbell DG, Cohen P. Identification of the 38-kDa subunit of rabbit skeletal muscle glycogen synthase as glycogenin. European Journal of Biochemistry. 169: 497-502. PMID 3121316 DOI: 10.1111/J.1432-1033.1987.Tb13637.X  0.4
1988 Pitcher J, Smythe C, Cohen P. Glycogenin is the priming glucosyltransferase required for the initiation of glycogen biogenesis in rabbit skeletal muscle. European Journal of Biochemistry. 176: 391-5. PMID 2970965 DOI: 10.1111/J.1432-1033.1988.Tb14294.X  0.438
1988 Cohen P. Protein phosphorylation and hormone action. Proceedings of the Royal Society B: Biological Sciences. 234: 115-144. PMID 2905457 DOI: 10.1098/Rspb.1988.0040  0.576
1988 Cohen P, Foulkes JG, Holmes CF, Nimmo GA, Tonks NK. Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle. Methods in Enzymology. 159: 427-37. PMID 2842607 DOI: 10.1016/0076-6879(88)59042-0  0.72
1988 McGowan CH, Cohen P. Protein phosphatase-2C from rabbit skeletal muscle and liver: an Mg2+-dependent enzyme. Methods in Enzymology. 159: 416-26. PMID 2842606 DOI: 10.1016/0076-6879(88)59041-9  0.461
1988 Stewart AA, Cohen P. Protein phosphatase-2B from rabbit skeletal muscle: a Ca2+-dependent, calmodulin-stimulated enzyme. Methods in Enzymology. 159: 409-16. PMID 2842605 DOI: 10.1016/0076-6879(88)59040-7  0.415
1988 Cohen P, Alemany S, Hemmings BA, Resink TJ, Strålfors P, Tung HY. Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle. Methods in Enzymology. 159: 390-408. PMID 2842604 DOI: 10.1016/0076-6879(88)59039-0  0.36
1988 Poulter L, Ang SG, Gibson BW, Williams DH, Holmes CF, Caudwell FB, Pitcher J, Cohen P. Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry. European Journal of Biochemistry. 175: 497-510. PMID 2842154 DOI: 10.1111/J.1432-1033.1988.Tb14222.X  0.673
1988 MacKintosh C, Campbell DG, Hiraga A, Cohen P. Phosphorylation of the glycogen-binding subunit of protein phosphatase-1G in response to adrenalin. Febs Letters. 234: 189-94. PMID 2839360 DOI: 10.1016/0014-5793(88)81331-0  0.713
1988 Chisholm AA, Cohen P. Identification of a third form of protein phosphatase 1 in rabbit skeletal muscle that is associated with myosin. Biochimica Et Biophysica Acta. 968: 392-400. PMID 2830909 DOI: 10.1016/0167-4889(88)90032-8  0.463
1988 Chisholm AA, Cohen P. The myosin-bound form of protein phosphatase 1 (PP-1M) is the enzyme that dephosphorylates native myosin in skeletal and cardiac muscles Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 971: 163-169. DOI: 10.1016/0167-4889(88)90188-7  0.409
1987 Nimmo HG, Cohen PT. Applications of recombinant DNA technology to studies of metabolic regulation. The Biochemical Journal. 247: 1-13. PMID 3318812 DOI: 10.1042/Bj2470001  0.482
1987 Pondaven P, Cohen P. Identification of protein phosphatases-1 and 2A and inhibitor-2 in oocytes of the starfish Asterias rubens and Marthasterias glacialis. European Journal of Biochemistry. 167: 135-40. PMID 3040398 DOI: 10.1111/J.1432-1033.1987.Tb13314.X  0.533
1987 McGowan CH, Campbell DG, Cohen P. Primary structure analysis proves that protein phosphatases 2C1 and 2C2 are isozymes. Biochimica Et Biophysica Acta. 930: 279-82. PMID 3040125 DOI: 10.1016/0167-4889(87)90041-3  0.329
1987 McGowan CH, Cohen P. Identification of two isoenzymes of protein phosphatase 2C in both rabbit skeletal muscle and liver. European Journal of Biochemistry / Febs. 166: 713-21. PMID 3038550 DOI: 10.1111/J.1432-1033.1987.Tb13570.X  0.388
1987 Holmes CF, Tonks NK, Major H, Cohen P. Analysis of the in vivo phosphorylation state of protein phosphatase inhibitor-2 from rabbit skeletal muscle by fast-atom bombardment mass spectrometry. Biochimica Et Biophysica Acta. 929: 208-19. PMID 3036252 DOI: 10.1016/0167-4889(87)90178-9  0.734
1987 Orgad S, Dudai Y, Cohen P. The protein phosphatases of Drosophila melanogaster and their inhibitors. European Journal of Biochemistry / Febs. 164: 31-8. PMID 3030753 DOI: 10.1111/J.1432-1033.1987.Tb10988.X  0.511
1987 Hiraga A, Kemp BE, Cohen P. Further studies on the structure of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle. European Journal of Biochemistry. 163: 253-8. PMID 3028798 DOI: 10.1111/J.1432-1033.1987.Tb10795.X  0.419
1987 Hiraga A, Cohen P. Phosphorylation of the glycogen-binding subunit of protein phosphatase-1G by cyclic-AMP-dependent protein kinase promotes translocation of the phosphatase from glycogen to cytosol in rabbit skeletal muscle. European Journal of Biochemistry. 161: 763-9. PMID 3024984 DOI: 10.1111/J.1432-1033.1986.Tb10505.X  0.523
1987 Berndt N, Campbell DG, Caudwell FB, Cohen P, da Cruz e Silva EF, da Cruz e Silva OB, Cohen PT. Isolation and sequence analysis of a cDNA clone encoding a type-1 protein phosphatase catalytic subunit: homology with protein phosphatase 2A. Febs Letters. 223: 340-6. PMID 2822491 DOI: 10.1016/0014-5793(87)80316-2  0.388
1986 Holmes CF, Campbell DG, Caudwell FB, Aitken A, Cohen P. The protein phosphatases involved in cellular regulation. Primary structure of inhibitor-2 from rabbit skeletal muscle. European Journal of Biochemistry. 155: 173-82. PMID 3512270  0.663
1986 Cohen P, Holmes CF, Poulter L, Gibson B, Williams DH. Identification of the C-terminus of rabbit skeletal muscle glycogen synthase. Biochemical and Biophysical Research Communications. 137: 542-5. PMID 3087361 DOI: 10.1016/0006-291X(86)91244-1  0.655
1986 Kuret J, Bell H, Cohen P. Identification of high levels of protein phosphatase-1 in rat liver nuclei. Febs Letters. 203: 197-202. PMID 3015674 DOI: 10.1016/0014-5793(86)80741-4  0.447
1986 Holmes CF, Kuret J, Chisholm AA, Cohen P. Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-II. Biochimica Et Biophysica Acta. 870: 408-16. PMID 3008843 DOI: 10.1016/0167-4838(86)90248-7  0.722
1986 Alemany S, Cohen P. Phosphorylase a is an allosteric inhibitor of the glycogen and microsomal forms of rat hepatic protein phosphatase-1. Febs Letters. 198: 194-202. PMID 3007211 DOI: 10.1016/0014-5793(86)80404-5  0.434
1986 Meijer L, Pondaven P, Tung HY, Cohen P, Wallace RW. Protein phosphorylation and oocyte maturation. II. Inhibition of starfish oocyte maturation by intracellular microinjection of protein phosphatases 1 and 2A and alkaline phosphatase. Experimental Cell Research. 163: 489-99. PMID 3007183 DOI: 10.1016/0014-4827(86)90079-0  0.455
1986 ALEMANY S, PELECH S, BRIERLEY CH, COHEN P. The protein phosphatases involved in cellular regulation: Evidence that dephosphorylation of glycogen phosphorylase and glycogen synthase in the glycogen and microsomal fractions of rat liver are catalysed by the same enzyme: protein phosphatase‐1 European Journal of Biochemistry. 156: 101-110. PMID 3007140 DOI: 10.1111/J.1432-1033.1986.Tb09554.X  0.47
1986 Caudwell FB, Hiraga A, Cohen P. Amino acid sequence of a region on the glycogen-binding subunit of protein phosphatase-1 phosphorylated by cyclic AMP-dependent protein kinase. Febs Letters. 194: 85-90. PMID 3000826 DOI: 10.1016/0014-5793(86)80056-4  0.503
1986 Cohen P. 11 Muscle Glycogen Synthase The Enzymes. 17: 461-497. DOI: 10.1016/S1874-6047(08)60436-9  0.542
1985 Pearson RB, Woodgett JR, Cohen P, Kemp BE. Substrate specificity of a multifunctional calmodulin-dependent protein kinase. The Journal of Biological Chemistry. 260: 14471-6. PMID 4055784  0.603
1985 Chisholm AA, Cohen P. Molecular mass of inhibitor-2 from rabbit liver. Biochimica Et Biophysica Acta. 847: 155-8. PMID 4052459 DOI: 10.1016/0167-4889(85)90168-5  0.398
1985 Kuret J, Woodgett JR, Cohen P. Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Identification of the sites phosphorylated by casein kinase-I. European Journal of Biochemistry / Febs. 151: 39-48. PMID 3928373 DOI: 10.1111/J.1432-1033.1985.Tb09066.X  0.685
1985 Cohen P. The coordinated control of metabolic pathways by broad-specificity protein kinases and phosphatases. Current Topics in Cellular Regulation. 27: 23-37. PMID 3004820 DOI: 10.1016/B978-0-12-152827-0.50010-4  0.539
1985 Van Hove L, Thoen C, Cohen P, Slegers H. Dephosphorylation of cytoplasmic non-polysomal messenger ribonucleoproteins from cryptobiotic gastrulae of Artemia salina Biochemical and Biophysical Research Communications. 131: 1241-1250. PMID 2996544 DOI: 10.1016/0006-291X(85)90224-4  0.508
1985 Thoen C, Van Hove L, Cohen P, Slegers H. Identification of protein phosphatases dephosphorylating mRNP proteins from cryptobiotic gastrulae of the brine shrimp A. salina Biochemical and Biophysical Research Communications. 131: 84-90. PMID 2994667 DOI: 10.1016/0006-291X(85)91773-5  0.413
1985 Cohen P. The role of protein phosphorylation in the hormonal control of enzyme activity. European Journal of Biochemistry. 151: 439-48. PMID 2992967 DOI: 10.1111/J.1432-1033.1985.Tb09121.X  0.466
1985 Newton D, Klee C, Woodgett J, Cohen P. Selective effects of CAPP1-calmodulin on its target proteins. Biochimica Et Biophysica Acta. 845: 533-9. PMID 2988645 DOI: 10.1016/0167-4889(85)90222-8  0.673
1985 TUNG HYL, PELECH S, FISHER MJ, POGSON CI, COHEN P. The protein phosphatases involved in cellular regulation: Influence of polyamines on the activities of protein phosphatase‐1 and protein phosphatase‐2A European Journal of Biochemistry. 149: 305-314. PMID 2986974 DOI: 10.1111/j.1432-1033.1985.tb08927.x  0.343
1985 Strålfors P, Hiraga A, Cohen P. The protein phosphatases involved in cellular regulation. Purification and characterisation of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle. European Journal of Biochemistry. 149: 295-303. PMID 2986973 DOI: 10.1111/J.1432-1033.1985.Tb08926.X  0.515
1985 PELECH S, COHEN P. The protein phosphatases involved in cellular regulation: 1. Modulation of protein phosphatases‐1 and 2 A by histone H 1, protamine, polylysine and heparin European Journal of Biochemistry. 148: 245-251. PMID 2985384 DOI: 10.1111/J.1432-1033.1985.Tb08832.X  0.52
1985 Cohen P. Hormones, second messengers and the reversible phosphorylation of proteins: An overview Bioessays. 2: 63-68. DOI: 10.1002/Bies.950020206  0.49
1984 Cohen P. Phosphorylase kinase from rabbit skeletal muscle. Methods in Enzymology. 99: 243-50. PMID 6417451 DOI: 10.1016/0076-6879(83)99059-6  0.522
1984 Woodgett JR, Cohen P, Yamauchi T, Fujisawa H. Comparison of calmodulin-dependent glycogen synthase kinase from skeletal muscle and calmodulin-dependent protein kinase-II from brain. Febs Letters. 170: 49-54. PMID 6327377 DOI: 10.1016/0014-5793(84)81366-6  0.68
1984 Aitken A, Klee CB, Cohen P. The structure of the B subunit of calcineurin. European Journal of Biochemistry / Febs. 139: 663-71. PMID 6321184 DOI: 10.1111/J.1432-1033.1984.Tb08055.X  0.406
1984 Tung HY, Resink TJ, Hemmings BA, Shenolikar S, Cohen P. The catalytic subunits of protein phosphatase-1 and protein phosphatase 2A are distinct gene products. European Journal of Biochemistry / Febs. 138: 635-41. PMID 6319140 DOI: 10.1111/J.1432-1033.1984.Tb07962.X  0.477
1984 Vulliet PR, Woodgett JR, Cohen P. Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase. The Journal of Biological Chemistry. 259: 13680-3. PMID 6150037  0.649
1984 Aitken A, Cohen P. [19] Identification of N-terminal myristyl blocking groups in proteins Methods in Enzymology. 106: 205-210. PMID 6092830 DOI: 10.1016/0076-6879(84)06021-3  0.475
1984 Tonks NK, Cohen P. The protein phosphatases involved in cellular regulation. Identification of the inhibitor-2 phosphatases in rabbit skeletal muscle. European Journal of Biochemistry. 145: 65-70. PMID 6092084 DOI: 10.1111/J.1432-1033.1984.Tb08522.X  0.506
1984 Tung HY, Cohen P. The protein phosphatases involved in cellular regulation. Comparison of native and reconstituted Mg-ATP-dependent protein phosphatases from rabbit skeletal muscle. European Journal of Biochemistry. 145: 57-64. PMID 6092083 DOI: 10.1111/J.1432-1033.1984.Tb08521.X  0.527
1984 Alemany S, Tung HY, Shenolikar S, Pilkis SJ, Cohen P. The protein phosphatases involved in cellular regulation. Antibody to protein phosphatase-2A as a probe of phosphatase structure and function. European Journal of Biochemistry / Febs. 145: 51-6. PMID 6092082 DOI: 10.1111/J.1432-1033.1984.Tb08520.X  0.433
1984 Pelech S, Cohen P, Fisher MJ, Pogson CI, El-Maghrabi MR, Pilkis SJ. The protein phosphatases involved in cellular regulation. Glycolysis, gluconeogenesis and aromatic amino acid breakdown in rat liver. European Journal of Biochemistry. 145: 39-49. PMID 6092081 DOI: 10.1111/J.1432-1033.1984.Tb08519.X  0.523
1984 Aitken A, Holmes CF, Campbell DG, Resink TJ, Cohen P, Leung CT, Williams DH. Amino acid sequence at the site on protein phosphatase inhibitor-2, phosphorylated by glycogen synthase kinase-3. Biochimica Et Biophysica Acta. 790: 288-91. PMID 6091765 DOI: 10.1016/0167-4838(84)90034-7  0.705
1984 Woodgett JR, Cohen P. Multisite phosphorylation of glycogen synthase. Molecular basis for the substrate specificity of glycogen synthase kinase-3 and casein kinase-II (glycogen synthase kinase-5). Biochimica Et Biophysica Acta. 788: 339-47. PMID 6087911 DOI: 10.1016/0167-4838(84)90047-5  0.685
1984 Hemmings HC, Greengard P, Tung HY, Cohen P. DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1. Nature. 310: 503-5. PMID 6087160 DOI: 10.1038/310503A0  0.383
1983 Aitken A, Cohen P. Isolation and characterisation of active fragments of protein phosphatase inhibitor-1 from rabbit skeletal muscle. Febs Letters. 147: 54-8. PMID 7140990 DOI: 10.1016/0014-5793(82)81010-7  0.421
1983 Picton C, Shenolikar S, Grand R, Cohen P. Calmodulin as an integral subunit of phosphorylase kinase from rabbit skeletal muscle. Methods in Enzymology. 102: 219-27. PMID 6645971 DOI: 10.1016/S0076-6879(83)02023-6  0.478
1983 Parker PJ, Caudwell FB, Cohen P. Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo European Journal of Biochemistry. 130: 227-234. PMID 6402364 DOI: 10.1111/J.1432-1033.1983.Tb07140.X  0.443
1983 McGuinness TL, Lai Y, Greengard P, Woodgett JR, Cohen P. A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase. Febs Letters. 163: 329-34. PMID 6315492 DOI: 10.1016/0014-5793(83)80846-1  0.685
1983 Woodgett JR, Davison MT, Cohen P. The calmodulin-dependent glycogen synthase kinase from rabbit skeletal muscle. Purification, subunit structure and substrate specificity. European Journal of Biochemistry / Febs. 136: 481-7. PMID 6315430 DOI: 10.1111/J.1432-1033.1983.Tb07766.X  0.7
1983 Tonks NK, Cohen P. Calcineurin is a calcium ion-dependent, calmodulin-stimulated protein phosphatase. Biochimica Et Biophysica Acta. 747: 191-3. PMID 6309241 DOI: 10.1016/0167-4838(83)90140-1  0.377
1983 Ingebritsen TS, Cohen P. Protein phosphatases: properties and role in cellular regulation. Science (New York, N.Y.). 221: 331-8. PMID 6306765 DOI: 10.1126/Science.6306765  0.433
1983 Resink TJ, Hemmings BA, Tung HY, Cohen P. Characterisation of a reconstituted Mg-ATP-dependent protein phosphatase. European Journal of Biochemistry. 133: 455-61. PMID 6303789 DOI: 10.1111/J.1432-1033.1983.Tb07485.X  0.505
1983 Donella-Deana A, Pinna LA, Hemmings B, Cohen P. Phosphorylation of K-casein by glycogen synthase kinase-3 from rabbit skeletal muscle. Biochimica Et Biophysica Acta. 745: 149-53. PMID 6303431 DOI: 10.1016/0167-4838(83)90043-2  0.545
1983 Foulkes JG, Strada SJ, Henderson PJ, Cohen P. A kinetic analysis of the effects of inhibitor-1 and inhibitor-2 on the activity of protein phosphatase-1. European Journal of Biochemistry. 132: 309-13. PMID 6301830 DOI: 10.1111/J.1432-1033.1983.Tb07363.X  0.43
1983 Ingebritsen TS, Stewart AA, Cohen P. The protein phosphatases involved in cellular regulation. 6. Measurement of type-1 and type-2 protein phosphatases in extracts of mammalian tissues; an assessment of their physiological roles. European Journal of Biochemistry. 132: 297-307. PMID 6301829 DOI: 10.1111/J.1432-1033.1983.Tb07362.X  0.521
1983 Stewart AA, Ingebritsen TS, Cohen P. The protein phosphatases involved in cellular regulation. 5. Purification and properties of a Ca2+/calmodulin-dependent protein phosphatase (2B) from rabbit skeletal muscle. European Journal of Biochemistry. 132: 289-95. PMID 6301828 DOI: 10.1111/J.1432-1033.1983.Tb07361.X  0.498
1983 Pato MD, Adelstein RS, Crouch D, Safer B, Ingebritsen TS, Cohen P. The protein phosphatases involved in cellular regulation. 4. Classification of two homogeneous myosin light chain phosphatases from smooth muscle as protein phosphatase-2A1 and 2C, and a homogeneous protein phosphatase from reticulocytes active on protein synthesis initiation factor eIF-2 as protein phosphatase-2A2. European Journal of Biochemistry. 132: 283-7. PMID 6301827 DOI: 10.1111/J.1432-1033.1983.Tb07360.X  0.671
1983 Ingebritsen TS, Foulkes JG, Cohen P. The protein phosphatases involved in cellular regulation. 2. Glycogen metabolism. European Journal of Biochemistry. 132: 263-74. PMID 6301825 DOI: 10.1111/J.1432-1033.1983.Tb07358.X  0.484
1983 Ingebritsen TS, Cohen P. The protein phosphatases involved in cellular regulation. 1. Classification and substrate specificities. European Journal of Biochemistry. 132: 255-61. PMID 6301824 DOI: 10.1111/J.1432-1033.1983.Tb07357.X  0.558
1983 Hemmings BA, Resink TJ, Cohen P. Reconstitution of a Mg-ATP-dependent protein phosphatase and its activation through a phosphorylation mechanism. Febs Letters. 150: 319-24. PMID 6297978 DOI: 10.1016/0014-5793(82)80760-6  0.514
1983 Damuni Z, Caudwell FB, Cohen P. Regulation of the aminoacyl-tRNA synthetase complex of rat liver by phosphorylation/dephosphorylation in vitro and in vivo. European Journal of Biochemistry. 129: 57-65. PMID 6297887 DOI: 10.1111/J.1432-1033.1982.Tb07020.X  0.419
1983 Hemmings BA, Aitken A, Cohen P, Rymond M, Hofmann F. Phosphorylation of the type-II regulatory subunit of cyclic-AMP-dependent protein kinase by glycogen synthase kinase 3 and glycogen synthase kinase 5. European Journal of Biochemistry. 127: 473-81. PMID 6293815 DOI: 10.1111/J.1432-1033.1982.Tb06896.X  0.564
1983 Cohen P. Protein phosphorylation and the control of glycogen metabolism in skeletal muscle. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 302: 13-25. PMID 6137000 DOI: 10.1098/Rstb.1983.0034  0.583
1983 Bennett J, Cohen P, Hanke DE, Pinna LA. Regulation of Photosynthesis by Chloroplast Protein Phosphorylation [and Discussion] Philosophical Transactions of the Royal Society B. 302: 113-125. DOI: 10.1098/Rstb.1983.0044  0.421
1983 Cohen P. Protein phosphorylation and hormone action — An overview Cell Biology International Reports. 7: 479-480. DOI: 10.1016/0309-1651(83)90138-8  0.457
1982 Aitken A, Cohen P, Santikarn S, Williams DH, Calder AG, Smith A, Klee CB. Identification of the NH2-terminal blocking group of calcineurin B as myristic acid. Febs Letters. 150: 314-8. PMID 7160476 DOI: 10.1016/0014-5793(82)80759-X  0.403
1982 Picton C, Woodgett J, Hemmings B, Cohen P. Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Phosphorylation of site 5 by glycogen synthase kinase-5 (casein kinase-II) is a prerequisite for phosphorylation of sites 3 by glycogen synthase kinase-3. Febs Letters. 150: 191-196. PMID 6819160 DOI: 10.1016/0014-5793(82)81332-X  0.659
1982 Picton C, Aitken A, Bilham T, Cohen P. Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Organisation of the seven sites in the polypeptide chain. European Journal of Biochemistry. 124: 37-45. PMID 6806097 DOI: 10.1111/J.1432-1033.1982.Tb05903.X  0.427
1982 Wettenhall REH, Cohen P, Caudwell B, Holland R. Differential phosphorylation of ribosomal protein S6 in isolated rat hepatocytes after incubation with insulin and glucagon. Febs Letters. 148: 207-213. PMID 6759164 DOI: 10.1016/0014-5793(82)80809-0  0.496
1982 Woodgett JR, Tonks NK, Cohen P. Identification of a calmodulin-dependent glycogen synthase kinase in rabbit skeletal muscle, distinct from phosphorylase kinase. Febs Letters. 148: 5-11. PMID 6293876 DOI: 10.1016/0014-5793(82)81231-3  0.674
1982 Aitken A, Bilham T, Cohen P. Complete primary structure of protein phosphatase inhibitor-1 from rabbit skeletal muscle. European Journal of Biochemistry. 126: 235-46. PMID 6290217 DOI: 10.1111/J.1432-1033.1982.Tb06771.X  0.503
1982 Wettenhall RE, Cohen P. Isolation and characterisation of cyclic AMP-dependent phosphorylation sites from rat liver ribosomal protein S6. Febs Letters. 140: 263-9. PMID 6282641 DOI: 10.1016/0014-5793(82)80910-1  0.402
1982 Cohen P, Yellowlees D, Aitken A, Donella-Deana A, Hemmings BA, Parker PJ. Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle. European Journal of Biochemistry. 124: 21-35. PMID 6282589 DOI: 10.1111/J.1432-1033.1982.Tb05902.X  0.566
1982 Cohen P. The role of protein phosphorylation in neural and hormonal control of cellular activity Nature. 296: 613-620. PMID 6280056 DOI: 10.1038/296613A0  0.476
1982 Stewart AA, Ingebritsen TS, Manalan A, Klee CB, Cohen P. Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80). Febs Letters. 137: 80-4. PMID 6279434 DOI: 10.1016/0014-5793(82)80319-0  0.326
1982 Hemmings BA, Yellowlees D, Kernohan JC, Cohen P. Purification of glycogen synthase kinase 3 from rabbit skeletal muscle. Copurification with the activating factor (FA) of the (Mg-ATP) dependent protein phosphatase. European Journal of Biochemistry. 119: 443-51. PMID 6273157 DOI: 10.1111/J.1432-1033.1981.Tb05628.X  0.587
1982 Cohen P. Protein phosphorylation: edited by Ora M. Rosen and Edwin G. Krebs, Cold Spring Harbor, 1981. Two-book set $140 (U.S.A.) $168 (elsewhere) (xxxvi + 142 pages) ISBN 0 87969 140 9 Trends in Biochemical Sciences. 7: 114-115. DOI: 10.1016/0968-0004(82)90161-X  0.379
1981 Grand RJ, Shenolikar S, Cohen P. The amino acid sequence of the delta subunit (calmodulin) of rabbit skeletal muscle phosphorylase kinase. European Journal of Biochemistry / Febs. 113: 359-67. PMID 7202416 DOI: 10.1111/J.1432-1033.1981.Tb05074.X  0.401
1981 Picton C, Klee CB, Cohen P. The regulation of muscle phosphorylase kinase by calcium ions, calmodulin and troponin-C. Cell Calcium. 2: 281-94. PMID 7200399 DOI: 10.1016/0143-4160(81)90021-X  0.467
1981 Cohen P. The role of calcium ions, calmodulin and troponin in the regulation of phosphorylase kinase from rabbit skeletal muscle. European Journal of Biochemistry. 111: 563-74. PMID 6780344 DOI: 10.1111/J.1432-1033.1980.Tb04972.X  0.438
1981 Kuznicki J, Grabarek Z, Brzeska H, Drabikowski W, Cohen P. Stimulation of enzyme activities by fragments of calmodulin. Febs Letters. 130: 141-5. PMID 6269885 DOI: 10.1016/0014-5793(81)80683-7  0.326
1981 Embi N, Parker PJ, Cohen P. A reinvestigation of the phosphorylation of rabbit skeletal-muscle glycogen synthase by cyclic-AMP-dependent protein kinase. Identification of the third site of phosphorylation as serine-7 European Journal of Biochemistry. 115: 405-413. PMID 6263629 DOI: 10.1111/J.1432-1033.1981.Tb05252.X  0.485
1981 Parker PJ, Aitken A, Bilham T, Embi N, Cohen P. Amino acid sequence of a region in rabbit skeletal muscle glycogen synthase phosphorylated by cyclic AMP-dependent protein kinase. Febs Letters. 123: 332-6. PMID 6262112 DOI: 10.1016/0014-5793(81)80321-3  0.51
1981 Stewart AA, Hemmings BA, Cohen P, Goris J, Merlevede W. The MgATP-dependent protein phosphatase and protein phosphatase 1 have identical substrate specificities. European Journal of Biochemistry. 115: 197-205. PMID 6262081 DOI: 10.1111/J.1432-1033.1981.Tb06217.X  0.573
1981 Guy PS, Cohen P, Hardie DG. Purification and physicochemical properties of ATP citrate (pro-3S) lyase from lactating rat mammary gland and studies of its reversible phosphorylation. European Journal of Biochemistry. 114: 399-405. PMID 6260494 DOI: 10.1111/J.1432-1033.1981.Tb05160.X  0.528
1981 Cohen P. Phosphorylation of rabbit skeletal muscle phosphorylase kinase by cyclic GMP-dependent protein kinase. Febs Letters. 119: 301-6. PMID 6253325 DOI: 10.1016/0014-5793(80)80277-8  0.546
1981 Stewart AA, Crouch D, Cohen P, Safer B. Classification of an eIF-2phosphatase as a type-2 protein phosphatase. Febs Letters. 119: 16-9. PMID 6253318 DOI: 10.1016/0014-5793(80)80988-4  0.388
1981 Ingebritsen TS, Foulkes JG, Cohen P. Identification Of Two Classes Of Broad Substrate Specificity Protein Phosphatase In Mammalian Tissues Biochemical Society Transactions. 9. DOI: 10.1042/Bst009241P  0.353
1981 Aitken A, Bilham T, Cohen P, Aswad D, Greengard P. THE SITES OF PHOSPHORYLATION ON C-SUBSTRATE FROM RABBIT CEREBELLUM AND THE MOLECULAR SPECIFICITIES OF CYCLIC CMP- AND CYCLIC AMP-DEPENDENT PROTEIN KINASES Biochemical Society Transactions. 9: 232P-232P. DOI: 10.1042/Bst009232Pc  0.53
1981 Cohen P. PROTEIN PHOSPHORYLATION AND THE REGULATION OF ENZYME ACTIVITY Biochemical Society Transactions. 9: 79P-79P. DOI: 10.1042/Bst009079P  0.51
1980 Picton C, Klee CB, Cohen P. Identification of a calmodulin-binding subunit on phosphorylase kinase [proceedings]. Biochemical Society Transactions. 8: 387. PMID 7399107 DOI: 10.1042/Bst0080387  0.469
1980 Cohen P, Klee CB, Picton C, Shenolikar S. Calcium control of muscle phosphorylase kinase through the combined action of calmodulin and troponin. Annals of the New York Academy of Sciences. 356: 151-61. PMID 6940494 DOI: 10.1111/J.1749-6632.1980.Tb29608.X  0.471
1980 Picton C, Klee CB, Cohen P. Phosphorylase kinase from rabbit skeletal muscle: identification of the calmodulin-binding subunits. European Journal of Biochemistry / Febs. 111: 553-61. PMID 6780343 DOI: 10.1111/J.1432-1033.1980.Tb04971.X  0.427
1980 Caudwell FB, Cohen P. Purification and subunit structure of glycogen-branching enzyme from rabbit skeletal muscle. European Journal of Biochemistry. 109: 391-4. PMID 6447599 DOI: 10.1111/J.1432-1033.1980.Tb04806.X  0.378
1980 Ingebritsen TS, Foulkes JG, Cohen P. The broad specificity protein phosphatase from mammalian liver. Separation of the Mr 35 000 catalytic subunit into two distinct enzymes. Febs Letters. 119: 9-15. PMID 6253321 DOI: 10.1016/0014-5793(80)80987-2  0.379
1980 Foulkes JG, Jefferson LS, Cohen P. The hormonal control of glycogen metabolism: dephosphorylation of protein phosphatase inhibitor-1 in vivo in response to insulin Febs Letters. 112: 21-24. PMID 6245928 DOI: 10.1016/0014-5793(80)80117-7  0.354
1980 Guy PS, Cohen P, Hardie DG. Rat mammary gland ATP-citrate lyase is phosphorylated by cyclic amp-dependent protein kinase. Febs Letters. 109: 205-8. PMID 6243582 DOI: 10.1016/0014-5793(80)81087-8  0.463
1980 Embi N, Rylatt DB, Cohen P. Glycogen synthase kinase-2 and phosphorylase kinase are the same enzyme. European Journal of Biochemistry. 100: 339-47. PMID 41708 DOI: 10.1111/J.1432-1033.1979.Tb04176.X  0.559
1980 Cohen P. Protein phosphorylation: edited by M. Weller, Pion Limited, London/Academic Press (London) Ltd., 1979. £29.00/$58.00 (557 pages) ISBN 0 85086 062 8; 0 12 0 0860628 Trends in Biochemical Sciences. 5. DOI: 10.1016/0968-0004(80)90266-2  0.417
1979 Foulkes JG, Cohen P. The Hormonal Control of Glycogen Metabolism Febs Journal. 97: 251-256. PMID 225171 DOI: 10.1111/J.1432-1033.1979.Tb13109.X  0.471
1979 Cohen P. The hormonal control of glycogen metabolism in mammalian muscle by multivalent phosphorylation. Biochemical Society Transactions. 7: 459-80. PMID 221283 DOI: 10.1042/Bst0070459  0.369
1979 Shenolikar S, Cohen PT, Cohen P, Nairn AC, Perry SV. The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle. European Journal of Biochemistry / Febs. 100: 329-37. PMID 159817 DOI: 10.1111/J.1432-1033.1979.Tb04175.X  0.506
1979 Marchand-Brustel YL, Cohen PTW, Cohen P. Insulin activates glycogen synthase in phosphorylase kinase deficient mice Febs Letters. 105: 235-238. PMID 114423 DOI: 10.1016/0014-5793(79)80619-5  0.417
1979 Cohen P, Picton C, Klee CB. Activation of phosphorylase kinase from rabbit skeletal muscle by calmodulin and troponin. Febs Letters. 104: 25-30. PMID 113254 DOI: 10.1016/0014-5793(79)81078-9  0.5
1979 Rylatt DB, Embi N, Cohen P. Glycogen synthase kinase-2 from rabbit skeletal muscle is activated by the calcium-dependent regulator protein. Febs Letters. 98: 76-80. PMID 107045 DOI: 10.1016/0014-5793(79)80155-6  0.478
1979 Rylatt DB, Cohen P. Amino acid sequence at the site on rabbit skeletal muscle glycogen synthase phosphorylated by the endogenous glycogen synthase kinase-2 activity. Febs Letters. 98: 71-5. PMID 107044 DOI: 10.1016/0014-5793(79)80154-4  0.585
1979 Hardie DG, Cohen P. Dephosphorylation and activation of acetyl-CoA carboxylase from lactating rabbit mammary gland. Febs Letters. 103: 333-8. PMID 38145 DOI: 10.1016/0014-5793(79)81356-3  0.313
1979 Hardie DG, Cohen P. Purification and physicochemical properties of fatty acid synthetase and acetyl-CoA carboxylase from lactating rabbit mammary gland. European Journal of Biochemistry. 92: 25-34. PMID 32036 DOI: 10.1111/J.1432-1033.1978.Tb12719.X  0.315
1978 Cohen P, Nimmo HG, Proud CG. How does insulin stimulate glycogen synthesis? Biochemical Society Symposium. 69-95. PMID 219866  0.668
1978 Shenolikar S, Foulkes JG, Cohen P. Isolation of an active fragment of protein phosphatase inhibitor-I from rabbit skeletal muscle. Biochemical Society Transactions. 6: 935-7. PMID 217761 DOI: 10.1042/Bst0060935  0.421
1978 Cohen P. The role of cyclic-AMP-dependent protein kinase in the regulation of glycogen metabolism in mammalian skeletal muscle. Current Topics in Cellular Regulation. 14: 117-196. PMID 215384 DOI: 10.1016/B978-0-12-152814-0.50008-3  0.531
1978 Cohen P, Nimmo GA, Burchell A, Antoniw JF. The substrate specificity and regulation of the protein phosphatases involved in the control of glycogen metabolism in mammalian skeletal muscle. Advances in Enzyme Regulation. 16: 97-119. PMID 211821 DOI: 10.1016/0065-2571(78)90069-9  0.59
1978 Nimmo GA, Cohen P. The Rigulation of Glycogen Metabolism Febs Journal. 87: 353-365. PMID 208845 DOI: 10.1111/J.1432-1033.1978.Tb12384.X  0.528
1978 Nimmo GA, Cohen P. The Regulation of Glycogen Metaabolism Febs Journal. 87: 341-351. PMID 208844 DOI: 10.1111/J.1432-1033.1978.Tb12383.X  0.497
1978 Burchell A, Cohen P. Is Phosphorylase Phosphatase a Manganese Metalloenzyme Biochemical Society Transactions. 6: 220-222. PMID 205463 DOI: 10.1042/Bst0060220A  0.42
1978 Cohen P, Nimmo GA. The purification and characterization of protein phosphatase inhibitor-1 from rabbit skeletal muscle. Biochemical Society Transactions. 6: 17-20. PMID 205460 DOI: 10.1042/Bst0060017  0.41
1978 Shenolikar S, Cohen P. The substrate specificity of cyclic AMP-dependent protein kinase: amino acid sequences at the phosphorylation sites of herring protamine (clupeine). Febs Letters. 86: 92-8. PMID 202510 DOI: 10.1016/0014-5793(78)80106-9  0.499
1978 Caudwell B, Antoniw JF, Cohen P. Calsequestrin, myosin, and the components of the protein-glycogen complex in rabbit skeletal muscle. European Journal of Biochemistry. 86: 511-8. PMID 95949 DOI: 10.1111/J.1432-1033.1978.Tb12334.X  0.447
1978 Hardie DG, Cohen P. The regulation of fatty acid biosynthesis: simple procedure for the purification of acetyl CoA carboxylase from lactating rabbit mammary gland, and its phosphorylation by endogenous cyclic AMP-dependent and -independent protein kinase activities. Febs Letters. 91: 1-7. PMID 27383 DOI: 10.1016/0014-5793(78)80005-2  0.511
1978 Cohen P, Burchell A, Foulkes JG, Cohen PTW, Vanaman TC, Nairin AC. Identification of the Ca2+-dependent modulator protein as the fourth subunit of rabbit skeletal muscle phosphorylase kinase Febs Letters. 92: 287-293. DOI: 10.1016/0014-5793(78)80772-8  0.381
1977 Nimmo HG, Cohen P. Hormonal control of protein phosphorylation. Advances in Cyclic Nucleotide Research. 8: 145-266. PMID 200126  0.624
1977 Proud CG, Rylatt DB, Yeaman SJ, Cohen P. Amino acid sequences at the two sites on glycogen synthetase phosphorylated by cyclic AMP-dependent protein kinase and their dephosphorylation by protein phosphatase-III Febs Letters. 80: 435-442. PMID 196939 DOI: 10.1016/0014-5793(77)80493-6  0.583
1977 Cohen P, Rylatt DB, Nimmo GA. The hormonal control of glycogen metabolism: the amino acid sequence at the phosphorylation site of protein phosphatase inhibitor-1. Febs Letters. 76: 182-6. PMID 193727 DOI: 10.1016/0014-5793(77)80147-6  0.586
1977 Cohen P, Nimmo GA, Antoniw JF. Specificity of a protein phosphatase inhibitor from rabbit skeletal muscle. The Biochemical Journal. 162: 435-44. PMID 192225 DOI: 10.1042/Bj1620435  0.521
1977 Antoniw JF, Nimmo HG, Yeaman SJ, Cohen P. Comparison of the substrate specificities of protein phosphatases involved in the regulation of glycogen metabolism in rabbit skeletal muscle Biochemical Journal. 162: 423-433. PMID 192224 DOI: 10.1042/Bj1620423  0.69
1977 Yeaman SJ, Cohen P, Watson DC, Dixon GH. The substrate specificity of adenosine 3':5' cyclic monophosphate dependent protein kinase of rabbit skeletal muscle Biochemical Journal. 162: 411-421. PMID 192223 DOI: 10.1042/Bj1620411  0.498
1977 Cohen P, Nimmo GA, Antoniw JF. A specific protein inhibitor of protein phosphatase-III from rabbit skeletal muscle. Biochemical Society Transactions. 4: 1033-5. PMID 191310 DOI: 10.1042/Bst0041033  0.423
1977 Antoniw JF, Cohen P. Specificities of the protein phosphatases involved in the regulation of glycogen metabolism in rabbit skeletal muscle. Biochemical Society Transactions. 4: 1030-2. PMID 191309 DOI: 10.1042/Bst0041030  0.373
1976 Burchell A, Cohen PTW, Cohen P. Distribution of isoenzymes of the glycogenolytic cascade in different types of muscle fibre. Febs Letters. 67: 17-22. PMID 1066284 DOI: 10.1016/0014-5793(76)80861-7  0.459
1976 Bates EJ, Heaton GM, Taylor C, Kernohan JC, Cohen P. Debranching enzyme from rabbit skeletal muscle; evidence for the location of two active centres on a single polypeptide chain. Febs Letters. 58: 181-5. PMID 1063726 DOI: 10.1016/0014-5793(75)80254-7  0.355
1976 Nimmo HG, Proud CG, Cohen P. The purification and properties of rabbit skeletal muscle glycogen synthase. European Journal of Biochemistry. 68: 21-30. PMID 823021 DOI: 10.1111/J.1432-1033.1976.Tb10761.X  0.64
1976 Cohen PTW, Burchell A, Cohen P. The Molecular Basis of Skeletal Muscle Phosphorylase Kinase Deficiency Febs Journal. 66: 347-356. PMID 820556 DOI: 10.1111/J.1432-1033.1976.Tb10524.X  0.397
1976 Yeaman SJ, Cohen P. The specificity of adenosine 3':5'-cyclic monophosphate-dependent protein kinase Biochemical Society Transactions. 4: 1027-1030. PMID 191308 DOI: 10.1042/bst0041027  0.455
1976 Antoniw JF, Cohen P. Separation of two phosphorylase kinase phosphatases from rabbit skeletal muscle. European Journal of Biochemistry. 68: 45-54. PMID 183956 DOI: 10.1111/J.1432-1033.1976.Tb10763.X  0.508
1976 Nimmo HG, Proud CG, Cohen P. The phosphorylation of rabbit skeletal muscle glycogen synthase by glycogen synthase kinase-2 and adenosine-3':5'-monophosphate-dependent protein kinase. European Journal of Biochemistry. 68: 31-44. PMID 183955 DOI: 10.1111/J.1432-1033.1976.Tb10762.X  0.738
1976 Cohen P, Antoniw JF, Nimmo HG, Yeaman SJ. Protein phosphorylation and hormone action | POLYPEPTIDE HORMONES: MOLECULAR AND CELLULAR ASPECTS Ciba Found.Symp.. 281-295. PMID 181225 DOI: 10.1002/9780470720233.ch15  0.701
1976 Cohen P. The regulation of protein function by multisite phosphorylation Trends in Biochemical Sciences. 1: 38-40. DOI: 10.1016/S0968-0004(76)80180-6  0.477
1975 Yeaman SJ, Cohen P. The hormonal control of activity of skeletal muscle phosphorylase kinase. Phosphorylation of the enzyme at two sites in vivo in response to adrenalin European Journal of Biochemistry. 51: 93-104. PMID 1122918 DOI: 10.1111/J.1432-1033.1975.Tb03910.X  0.497
1975 Taylor C, Cox AJ, Kernohan JC, Cohen P. Debranching enzyme from rabbit skeletal muscle. Purification, properties and physiological role. Febs Journal. 51: 105-115. PMID 1122910 DOI: 10.1111/J.1432-1033.1975.Tb03911.X  0.408
1975 Cohen P, Rosemeyer MA. Glucose-6-phosphate dehydrogenase from human erythrocytes. Methods in Enzymology. 41: 208-14. PMID 236440 DOI: 10.1016/S0076-6879(75)41049-7  0.66
1975 Nimmo HG, Cohen P. Glycogen synthetase kinase 2 and adenosine 3':5'-cyclic monophosphate-independent protein kinase activities in rabbit skeletal muscle. Biochemical Society Transactions. 3: 85-6. PMID 236205 DOI: 10.1042/Bst0030085  0.721
1975 Antoniw JF, Cohen P. Separation of two phosphorylase kinase phosphatase activities in rabbit skeletal muscle. Biochemical Society Transactions. 3: 83-4. PMID 165110 DOI: 10.1042/Bst0030083  0.567
1975 Cohen P, Watson DC, Dixon GH. The hormonal control of activity of skeletal muscle phosphorylase kinase. Amino acid sequences at the two sites of action of adenosine 3':5' monophosphate dependent protein kinase European Journal of Biochemistry. 51: 79-92. PMID 164350 DOI: 10.1111/J.1432-1033.1975.Tb03909.X  0.495
1975 Cohen P, Antoniw JF, Nimmo HG, Proud CG. Structure and Regulation of Enzymes for the Degradation and Resynthesis of Glycogen Biochemical Society Transactions. 3: 849-854. DOI: 10.1042/Bst0030849  0.597
1974 Nimmo HG, Cohen P. Glycogen synthetase kinase 2 (GSK 2); the identification of a new protein kinase in skeletal muscle. Febs Letters. 47: 162-6. PMID 4372086 DOI: 10.1016/0014-5793(74)80450-3  0.722
1974 Yeaman SJ, Cohen P. Demonstration of the control of rabbit skeletal muscle phosphorylase kinase activity in vivo by adenosine 3: 5 cyclic monophosphate dependent protein kinase Biochemical Society Transactions. 2: 931-932. DOI: 10.1042/Bst0020931  0.538
1974 Cohen P. Isolation of a Unique Phosphopeptide from Skeletal-Muscle Phosphorylase Kinase, Labelled During Activation by Adenosine 3′:5′-Cyclic Monophosphate-Dependent Protein Kinase Biochemical Society Transactions. 2: 82-83. DOI: 10.1042/Bst0020082  0.531
1973 Cohen P, Saari JC, Fischer EH. Comparative study of dogfish and rabbit muscle phosphorylases. Biochemistry. 12: 5233-41. PMID 4796798 DOI: 10.1021/Bi00750A002  0.54
1973 Cohen P, Antoniw JF. The control of phosphorylase kinase phosphatase by "second site phosphorylation"; a new form of enzyme regulation. Febs Letters. 34: 43-7. PMID 4354140 DOI: 10.1016/0014-5793(73)80699-4  0.487
1973 Cohen P. The subunit structure of rabbit-skeletal-muscle phosphorylase kinase, and the molecular basis of its activation reactions. European Journal of Biochemistry. 34: 1-14. PMID 4349654 DOI: 10.1111/J.1432-1033.1973.Tb02721.X  0.431
1973 Cohen P. Activation and phosphorylation of the subunits of phosphorylase kinase. The Biochemical Journal. 130: 5P-6P. PMID 4347797 DOI: 10.1042/Bj1300005Pb  0.525
1973 Cohen PTWW, Cohen P. Skeletal muscle phosphorylase kinase deficiency: detection of a protein lacking any activity in ICR-IAn mice. Febs Letters. 29: 113-116. PMID 4198146 DOI: 10.1016/0014-5793(73)80538-1  0.476
1972 Kendal AP, Eckert EA, Cohen P. The preparation and properties of 14C-carboxamido-methylated subunits from A2/1957 influenza neuraminidase Biochimica Et Biophysica Acta. 258: 484-495. PMID 5062247 DOI: 10.1016/0005-2744(72)90240-9  0.337
1972 Cohen P, Fischer EH. [134] Phosphorylase from dogfish skeletal muscle Methods in Enzymology. 28: 963-967. DOI: 10.1016/0076-6879(72)28140-X  0.54
1971 Cohen P, Duewer T, Fischer EH. Phosphorylase from dogfish skeletal muscle. Purification and a comparison of its physical properties to those of rabbit muscle phosphorylase. Biochemistry. 10: 2683-94. PMID 5558692 DOI: 10.1021/Bi00790A005  0.539
1970 Barnicot NA, Cohen P. Red cell enzymes of primates (Anthropoidea). Biochemical Genetics. 4: 41-57. PMID 4986300 DOI: 10.1007/Bf00484017  0.352
1969 Cohen P, Rosemeyer MA. Subunit interactions of glucose-6-phosphate dehydrogenase from human erythrocytes. European Journal of Biochemistry. 8: 8-15. PMID 5781270 DOI: 10.1111/J.1432-1033.1969.Tb00488.X  0.674
1969 Cohen P, Rosemeyer MA. Human glucose-6-phosphate dehydrogenase: purification of the erythrocyte enzyme and the influence of ions on its activity. European Journal of Biochemistry. 8: 1-7. PMID 5781268 DOI: 10.1111/J.1432-1033.1969.Tb00487.X  0.687
1968 Cohen P, Rosemeyer MA. The molecular weight and subunit structure of glucose-6-phosphate dehydrogenase from human erythrocytes. Febs Letters. 1: 147-149. PMID 11945277 DOI: 10.1016/0014-5793(68)80043-2  0.675
1968 Cohen P, Rosemeyer MA. The molecular weight and subunit structure of glucose-6-phosphate dehydrogenase from human erythrocytes Febs Letters. 1: 147-149.  0.655
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