| Year |
Citation |
Score |
| 2022 |
Crosby D, Bhatia S, Brindle KM, Coussens LM, Dive C, Emberton M, Esener S, Fitzgerald RC, Gambhir SS, Kuhn P, Rebbeck TR, Balasubramanian S. Early detection of cancer. Science (New York, N.Y.). 375: eaay9040. PMID 35298272 DOI: 10.1126/science.aay9040 |
0.309 |
|
| 2019 |
DeBerardinis R, Brindle K. Decision letter: Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice Elife. DOI: 10.7554/Elife.46312.015 |
0.318 |
|
| 2018 |
Hesketh RL, Brindle KM. Magnetic resonance imaging of cancer metabolism with hyperpolarized C-labeled cell metabolites. Current Opinion in Chemical Biology. 45: 187-194. PMID 30007214 DOI: 10.1016/j.cbpa.2018.03.004 |
0.311 |
|
| 2018 |
Mayerhoefer ME, Raderer M, Jaeger U, Staber P, Kiesewetter B, Senn D, Gallagher FA, Brindle K, Porpaczy E, Weber M, Berzaczy D, Simonitsch-Klupp I, Sillaber C, Skrabs C, Haug A. Ultra-early response assessment in lymphoma treatment: [F]FDG PET/MR captures changes in glucose metabolism and cell density within the first 72 hours of treatment. European Journal of Nuclear Medicine and Molecular Imaging. 45: 931-940. PMID 29480328 DOI: 10.1007/S00259-018-3937-Z |
0.301 |
|
| 2018 |
Shishmarev D, Wright AJ, Rodrigues TB, Pileio G, Stevanato G, Brindle KM, Kuchel PW. Sub-minute kinetics of human red cell fumarase: 1 H spin-echo NMR spectroscopy and 13 C rapid-dissolution dynamic nuclear polarization. Nmr in Biomedicine. PMID 29315908 DOI: 10.1002/Nbm.3870 |
0.309 |
|
| 2018 |
Aboagye E, Aigbirhio F, Allott L, Anderson E, Artelsmair M, Audisio D, Audisio J, Bragg R, Brindle K, Bulat F, Bürli R, Carroll L, Chapdelaine M, Collins S, Cortezon-Tamarit F, et al. Abstracts of the 26th international isotope society (UK group) symposium: Synthesis & applications of labelled compounds 2017 Journal of Labelled Compounds and Radiopharmaceuticals. 61: 1115-1130. DOI: 10.1002/jlcr.3641 |
0.41 |
|
| 2017 |
Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM. Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models. Ejnmmi Research. 7: 99. PMID 29247446 DOI: 10.1186/S13550-017-0349-1 |
0.665 |
|
| 2017 |
Neves AA, Xie B, Fawcett S, Alam IS, Witney TH, de Backer MM, Summers J, Hughes W, McGuire S, Soloviev D, Miller J, Howat WJ, Hu DE, Rodrigues TB, Lewis DY, ... Brindle KM, et al. Rapid Imaging of Tumor Cell Death in vivo using the C2A domain of Synaptotagmin-I. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28209913 DOI: 10.2967/Jnumed.116.183004 |
0.665 |
|
| 2016 |
O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, ... ... Brindle KM, et al. Imaging biomarker roadmap for cancer studies. Nature Reviews. Clinical Oncology. PMID 27725679 DOI: 10.1038/Nrclinonc.2016.162 |
0.42 |
|
| 2016 |
Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM. The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models. Ejnmmi Research. 6: 63. PMID 27515446 DOI: 10.1186/S13550-016-0218-3 |
0.677 |
|
| 2016 |
Pietro MD, Neves A, O’Donovan M, Waterhouse D, Bohndiek S, Brindle K, Fitzgerald R. OC-053 Lectin-Based Near infra-red Molecular Imaging for Dysplasia Detection in Barrett’s Oesophagus: An ex-vivo Study on Human Tissue Gut. 65. DOI: 10.1136/Gutjnl-2016-312388.52 |
0.316 |
|
| 2016 |
Henderson F, Lewis D, Soloviev D, Brindle K, McMahon A, Williams K. MALDI-MS and [11C] acetate PET imaging of lipid heterogeneity in non-small-cell lung cancer European Journal of Cancer. 61: S55. DOI: 10.1016/S0959-8049(16)61189-9 |
0.303 |
|
| 2012 |
Clatworthy MR, Kettunen MI, Hu DE, Mathews RJ, Witney TH, Kennedy BW, Bohndiek SE, Gallagher FA, Jarvis LB, Smith KG, Brindle KM. Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 13374-9. PMID 22837393 DOI: 10.1073/pnas.1205539109 |
0.649 |
|
| 2012 |
Brindle K. Watching tumours gasp and die with MRI: the promise of hyperpolarised 13C MR spectroscopic imaging British Journal of Radiology. 85: 697-708. PMID 22496072 DOI: 10.1259/Bjr/81120511 |
0.364 |
|
| 2012 |
Kennedy BW, Kettunen MI, Hu DE, Brindle KM. Probing lactate dehydrogenase activity in tumors by measuring hydrogen/deuterium exchange in hyperpolarized l-[1-(13)C,U-(2)H]lactate. Journal of the American Chemical Society. 134: 4969-77. PMID 22316419 DOI: 10.1021/ja300222e |
0.317 |
|
| 2011 |
Witney TH, Kettunen MI, Brindle KM. Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells. The Journal of Biological Chemistry. 286: 24572-80. PMID 21596745 DOI: 10.1074/jbc.M111.237727 |
0.69 |
|
| 2011 |
Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev EY, Comment A, Cunningham CH, Deberardinis RJ, Green GG, Leach MO, Rajan SS, Rizi RR, Ross BD, Warren WS, Malloy CR. Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia (New York, N.Y.). 13: 81-97. PMID 21403835 DOI: 10.1593/Neo.101102 |
0.365 |
|
| 2010 |
Bohndiek SE, Kettunen MI, Hu DE, Witney TH, Kennedy BW, Gallagher FA, Brindle KM. Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy. Molecular Cancer Therapeutics. 9: 3278-88. PMID 21159611 DOI: 10.1158/1535-7163.MCT-10-0706 |
0.685 |
|
| 2010 |
Witney TH, Kettunen MI, Hu DE, Gallagher FA, Bohndiek SE, Napolitano R, Brindle KM. Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate. British Journal of Cancer. 103: 1400-6. PMID 20924379 DOI: 10.1038/sj.bjc.6605945 |
0.686 |
|
| 2010 |
Witney TH, Brindle KM. Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy. Biochemical Society Transactions. 38: 1220-4. PMID 20863288 DOI: 10.1042/BST0381220 |
0.703 |
|
| 2010 |
Alam IS, Neves AA, Witney TH, Boren J, Brindle KM. Comparison of the C2A domain of synaptotagmin-I and annexin-V as probes for detecting cell death. Bioconjugate Chemistry. 21: 884-91. PMID 20402461 DOI: 10.1021/bc9004415 |
0.654 |
|
| 2010 |
Kettunen MI, Hu DE, Witney TH, McLaughlin R, Gallagher FA, Bohndiek SE, Day SE, Brindle KM. Magnetization transfer measurements of exchange between hyperpolarized [1-13C]pyruvate and [1-13C]lactate in a murine lymphoma. Magnetic Resonance in Medicine. 63: 872-80. PMID 20373388 DOI: 10.1002/mrm.22276 |
0.683 |
|
| 2009 |
Gallagher FA, Kettunen MI, Hu DE, Jensen PR, Zandt RIt, Karlsson M, Gisselsson A, Nelson SK, Witney TH, Bohndiek SE, Hansson G, Peitersen T, Lerche MH, Brindle KM. Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors Proceedings of the National Academy of Sciences of the United States of America. 106: 19801-19806. PMID 19903889 DOI: 10.1073/pnas.0911447106 |
0.685 |
|
| 2009 |
Witney TH, Kettunen MI, Day SE, Hu DE, Neves AA, Gallagher FA, Fulton SM, Brindle KM. A comparison between radiolabeled fluorodeoxyglucose uptake and hyperpolarized (13)C-labeled pyruvate utilization as methods for detecting tumor response to treatment. Neoplasia (New York, N.Y.). 11: 574-82, 1 p followin. PMID 19484146 DOI: 10.1593/NEO.09254 |
0.685 |
|
| 2000 |
Domingo Z, Bradley JK, Blamire AM, Brindle K, Styles P, Rajagopalan B. Diffusion weighted imaging and magnetic resonance spectroscopy in a low flow ischaemia model due to endothelin induced vasospasm. Nmr in Biomedicine. 13: 154-62. PMID 10861995 DOI: 10.1002/1099-1492(200005)13:3<154::Aid-Nbm620>3.0.Co;2-W |
0.312 |
|
| 1989 |
Brindle K, Williams S, Boulton M. 19F NMR detection of a fluorine-labelled enzyme in vivo Febs Letters. 255: 121-124. DOI: 10.1016/0014-5793(89)81073-7 |
0.387 |
|
| 1988 |
Mitsumori F, Rees D, Brindle KM, Radda GK, Campbell ID. 31P-NMR saturation transfer studies of aerobic Escherichia coli cells. Biochimica Et Biophysica Acta. 969: 185-93. PMID 2895671 DOI: 10.1016/0167-4889(88)90074-2 |
0.475 |
|
| 1987 |
Brindle KM, Campbell ID. NMR studies of kinetics in cells and tissues. Quarterly Reviews of Biophysics. 19: 159-82. PMID 3310078 DOI: 10.1017/S003358350000411X |
0.442 |
|
| 1986 |
Brindle KM, Campbell ID, Simpson RJ. A 1H-NMR study of the activity expressed by lactate dehydrogenase in the human erythrocyte. European Journal of Biochemistry. 158: 299-305. PMID 3732272 DOI: 10.1111/J.1432-1033.1986.Tb09751.X |
0.495 |
|
| 1985 |
Brindle K, Krikler S. 31P-NMR saturation transfer measurements of phosphate consumption in Saccharomyces cerevisiae Biochimica Et Biophysica Acta. 847: 285-292. DOI: 10.1016/0167-4889(85)90033-3 |
0.318 |
|
| 1984 |
Oxley ST, Porteous R, Brindle KM, Boyd J, Campbell ID. A multinuclear NMR study of 2,3-bisphosphoglycerate metabolism in the human erythrocyte. Biochimica Et Biophysica Acta. 805: 19-24. PMID 6477971 DOI: 10.1016/0167-4889(84)90031-4 |
0.496 |
|
| 1984 |
Foxall DL, Brindle KM, Campbell ID, Simpson RJ. The inhibition of erythrocyte glyceraldehyde-3-phosphate dehydrogenase. In situ PMR studies. Biochimica Et Biophysica Acta. 804: 209-15. PMID 6372868 DOI: 10.1016/0167-4889(84)90151-4 |
0.467 |
|
| 1984 |
Paul HH, Brindle KM, Campbell ID, Smith DJ. Proton NMR measurements of hydrogen exchange at the C-3 position of 3-hydroxybutyrate in suspensions of rat liver mitochondria. Febs Letters. 163: 185-8. PMID 6315486 DOI: 10.1016/0014-5793(83)80815-1 |
0.461 |
|
| 1984 |
Brindle KM, Porteous R, Campbell ID. 1H NMR measurements of enzyme-catalyzed 15N-label exchange Journal of Magnetic Resonance (1969). 56: 543-547. DOI: 10.1016/0022-2364(84)90320-2 |
0.464 |
|
| 1984 |
Boyd J, Brindle K, Campbell I, Radda G. A comparison of one-dimensional and two-dimensional NMR methods for measuring enzyme-catalyzed exchange Journal of Magnetic Resonance (1969). 60: 149-155. DOI: 10.1016/0022-2364(84)90041-6 |
0.431 |
|
| 1983 |
Brindle KM, Campbell ID, Simpson RJ. A 1H n.m.r. study of the kinetic properties expressed by glyceraldehyde phosphate dehydrogenase in the intact human erythrocyte. The Biochemical Journal. 208: 583-92. PMID 7165719 DOI: 10.1042/Bj2080583 |
0.491 |
|
| 1983 |
Simpson RJ, Brindle KM, Campbell ID. Spin ECHO proton NMR studies of the metabolism of malate and fumarate in human erythrocytes. Dependence on free NAD levels. Biochimica Et Biophysica Acta. 721: 191-200. PMID 7138916 DOI: 10.1016/0167-4889(82)90068-4 |
0.474 |
|
| 1983 |
Simpson RJ, Brindle KM, Campbell ID. Centrifugal analysis of undiluted packed human erythrocyte lysates. Studies of the association of glyceraldehyde-phosphate dehydrogenase with the membrane fraction. Biochimica Et Biophysica Acta. 758: 187-90. PMID 6871248 DOI: 10.1016/0304-4165(83)90301-X |
0.424 |
|
| 1983 |
Brindle KM, Boyd J, Campbell ID, Porteous R, Soffe N. Observation of carbon labelling in cell metabolites using proton spin echo NMR. Biochemical and Biophysical Research Communications. 109: 864-71. PMID 6297492 DOI: 10.1016/0006-291X(82)92020-4 |
0.51 |
|
| 1983 |
SIMPSON RJ, BRINDLE KM, CAMPBELL ID. Association of aldolase with the membranes in concentrated human erythrocyte lysates Biochemical Society Transactions. 11: 281-282. DOI: 10.1042/Bst0110281 |
0.386 |
|
| 1983 |
BRINDLE KM, CAMPBELL ID, SIMPSON RJ. 1H n.m.r. studies of the kinetic properties expressed by erythrocyte enzymes in situ and in vitro Biochemical Society Transactions. 11: 280-281. DOI: 10.1042/Bst0110280 |
0.412 |
|
| 1983 |
Foxall DL, Brindle KM, Campbell I, Simpson RJ. An NMR investigation of isotope exchange involving multiply labelled intermediates Tetrahedron. 39: 3443-3448. DOI: 10.1016/S0040-4020(01)88654-3 |
0.468 |
|
| 1982 |
Simpson RJ, Brindle KM, Brown FF, Campbell ID, Foxall DL. Studies of pyruvate-water isotope exchange catalysed by erythrocytes and proteins. The Biochemical Journal. 193: 401-6. PMID 7305939 DOI: 10.1042/Bj1930401 |
0.416 |
|
| 1982 |
Brindle KM, Brown FF, Campbell ID, Foxall DL, Simpson RJ. A 1H n.m.r. study of isotope exchange catalysed by glycolytic enzymes in the human erythrocyte. The Biochemical Journal. 202: 589-602. PMID 7092833 DOI: 10.1042/Bj2020589 |
0.489 |
|
| 1982 |
Simpson RJ, Brindle KM, Brown FF, Campbell ID, Foxall DL. Studies of lactate dehydrogenase in the purified state and in intact erythrocytes. The Biochemical Journal. 202: 581-7. PMID 7092832 DOI: 10.1042/Bj2020581 |
0.472 |
|
| 1982 |
Simpson RJ, Brindle KM, Brown FF, Campbell ID, Foxall DL. A p.m.r. isotope-exchange method for studying the kinetic properties of dehydrogenases in intact cells. The Biochemical Journal. 202: 573-9. PMID 7092831 DOI: 10.1042/Bj2020573 |
0.434 |
|
| 1981 |
Brindle KM, Brown FF, Campbell ID, Foxall DL, Simpson RJ. 1H/2H isotope exchange studies in intact erythrocytes. Biochemical Society Transactions. 8: 646-7. PMID 7450272 DOI: 10.1042/Bst0080646 |
0.447 |
|
| 1981 |
Brand S, Brindle K, Brown F, Campbell I, Eliot C, Foxall D, Jaroszkiewicz E, Simpson R, Styles P. STUDIES OF TRANSPORT IN SUSPENSIONS OF WHOLE CELLS USING NMR Biochemical Society Transactions. 9: 176P-176P. DOI: 10.1042/Bst009176Pa |
0.492 |
|
| 1980 |
BRAND SC, BRINDLE KM, BROWN FF, CAMPBELL ID, ELIOT CG, FOXALL DL, JAROSZKIEWICZ E, SIMPSON RJ, STYLES P. Studies of transport in suspensions of whole cells by using nuclear magnetic resonance Biochemical Society Transactions. 8: 647-647. DOI: 10.1042/Bst0080647 |
0.436 |
|
| 1979 |
Brindle KM, Brown FF, Campbell ID, Grathwohl C, Kuchel PW. Application of spin-echo nuclear magnetic resonance to whole-cell systems. Membrane transport. The Biochemical Journal. 180: 37-44. PMID 486105 DOI: 10.1042/Bj1800037 |
0.468 |
|
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